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Conserved domains on  [gi|17943220|pdb|1JZ5|C]
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Chain C, Beta-Galactosidase

Protein Classification

beta-galactosidase( domain architecture ID 11484318)

beta-galactosidase catalyzes the hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
lacZ PRK09525
beta-galactosidase;
3-1023 0e+00

beta-galactosidase;


:

Pssm-ID: 236548 [Multi-domain]  Cd Length: 1027  Bit Score: 2185.48  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C          3 HMLEDPVVLQRRDWENPGVTQLNRLAAHPPFASWRNSEEARTDRPSQQLRSLNGEWRFAWFPAPEAVPESWLECDLPEAD 82
Cdd:PRK09525    4 IMDSLAQILARRDWENPGVTQLNRLPAHPPFASWRNSEAARDDRPSQQRQSLNGEWRFSYFPAPEAVPESWLECDLPDAD 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C         83 TVVVPSNWQMHGYDAPIYTNVTYPITVNPPFVPTENPTGCYSLTFNVDESWLQEGQTRIIFDGVNSAFHLWCNGRWVGYG 162
Cdd:PRK09525   84 TIPVPSNWQLHGYDAPIYTNVTYPIPVNPPFVPEENPTGCYSLTFTVDESWLQSGQTRIIFDGVNSAFHLWCNGRWVGYS 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C        163 QDSRLPSEFDLSAFLRAGENRLAVMVLRWSDGSYLEDQDMWRMSGIFRDVSLLHKPTTQISDFHVATRFNDDFSRAVLEA 242
Cdd:PRK09525  164 QDSRLPAEFDLSPFLRAGENRLAVMVLRWSDGSYLEDQDMWRMSGIFRDVSLLHKPTTQLSDFHITTELDDDFRRAVLEV 243
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C        243 EVQMCGELRDYLRVTVSLWQGETQVASGTAPFGGEIIDERGGYADRVTLRLNVENPKLWSAEIPNLYRAVVELHTADGTL 322
Cdd:PRK09525  244 EAQVNGELRDELRVTVQLWDGETLVASGTAPFGTEIIDERGAYADRVTLRLNVENPKLWSAETPNLYRAVVSLLDADGTL 323
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C        323 IEAEACDVGFREVRIENGLLLLNGKPLLIRGVNRHEHHPLHGQVMDEQTMVQDILLMKQNNFNAVRCSHYPNHPLWYTLC 402
Cdd:PRK09525  324 IEAEAYDVGFRKVEIENGLLKLNGKPLLIRGVNRHEHHPEHGQVMDEETMVQDILLMKQHNFNAVRCSHYPNHPLWYELC 403
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C        403 DRYGLYVVDEANIETHGMVPMNRLTDDPRWLPAMSERVTRMVQRDRNHPSVIIWSLGNESGHGANHDALYRWIKSVDPSR 482
Cdd:PRK09525  404 DRYGLYVVDEANIETHGMVPMNRLSDDPRWLPAMSERVTRMVQRDRNHPSIIIWSLGNESGHGANHDALYRWIKSNDPSR 483
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C        483 PVQYEGGGADTTATDIICPMYARVDEDQPFPAVPKWSIKKWLSLPGETRPLILCEYAHAMGNSLGGFAKYWQAFRQYPRL 562
Cdd:PRK09525  484 PVQYEGGGADTAATDIICPMYARVDEDQPFPAVPKWSIKKWISLPGETRPLILCEYAHAMGNSLGGFAKYWQAFRQYPRL 563
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C        563 QGGFVWDWVDQSLIKYDENGNPWSAYGGDFGDTPNDRQFCMNGLVFADRTPHPALTEAKHQQQFFQFRL---SGQTIEVT 639
Cdd:PRK09525  564 QGGFIWDWVDQGLTKYDENGNPWWAYGGDFGDTPNDRQFCMNGLVFPDRTPHPALYEAKHAQQFFQFSLlstTPLTIEVT 643
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C        640 SEYLFRHSDNELLHWMVALDGKPLASGEVPLDVAPQGKQLIELPELPQPESAGQLWLTVRVVQPNATAWSEAGHISAWQQ 719
Cdd:PRK09525  644 SEYLFRHSDNELLHWSVALDGKPLASGEVPLDLAPQGSQRITLPELPQPESAGQLWLNVEVVQPNATAWSEAGHRSAWQQ 723
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C        720 WRLAENLSVTLPAASHAIPHLTTSEMDFCIELGNKRWQFNRQSGFLSQMWIGDKKQLLTPLRDQFTRAPLDNDIGVSEAT 799
Cdd:PRK09525  724 WRLPEPLSLPLPTASHAAPQLTQDEQDFCIELGNQRWQFNRQSGLLSQWWVGGKEQLLTPLRDQFTRAPLDNDIGVSEAT 803
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C        800 RIDPNAWVERWKAAGHYQAEAALLQCTADTLADAVLITTAHAWQHQGKTLFISRKTYRIDGSGQMAITVDVEVASDTPHP 879
Cdd:PRK09525  804 RIDPNAWVERWKAAGLYQLEARLLQCDADTLADAVLITTEHAYQHQGKTLFISRKTYRIDGQGEMTIDVDVEVASDLPPP 883
                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C        880 ARIGLNCQLAQVAERVNWLGLGPQENYPDRLTAACFDRWDLPLSDMYTPYVFPSENGLRCGTRELNYGPHQWRGDFQFNI 959
Cdd:PRK09525  884 ARIGLTCQLAQVAERVSWLGLGPHENYPDRLLAACFGRWDLPLSDMHTPYIFPSENGLRCGTRELNYGRHQIRGDFHFNI 963
                         970       980       990      1000      1010      1020
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
1JZ5_C        960 SRYSQQQLMETSHRHLLHAEEGTWLNIDGFHMGIGGDDSWSPSVSAEFQLSAGRYHYQLVWCQK 1023
Cdd:PRK09525  964 SRYSQQQLMETSHRHLLQAEEGTWLNIDGFHMGVGGDDSWSPSVHPEFLLSAGRYHYQLTWCQK 1027
 
Name Accession Description Interval E-value
lacZ PRK09525
beta-galactosidase;
3-1023 0e+00

beta-galactosidase;


Pssm-ID: 236548 [Multi-domain]  Cd Length: 1027  Bit Score: 2185.48  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C          3 HMLEDPVVLQRRDWENPGVTQLNRLAAHPPFASWRNSEEARTDRPSQQLRSLNGEWRFAWFPAPEAVPESWLECDLPEAD 82
Cdd:PRK09525    4 IMDSLAQILARRDWENPGVTQLNRLPAHPPFASWRNSEAARDDRPSQQRQSLNGEWRFSYFPAPEAVPESWLECDLPDAD 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C         83 TVVVPSNWQMHGYDAPIYTNVTYPITVNPPFVPTENPTGCYSLTFNVDESWLQEGQTRIIFDGVNSAFHLWCNGRWVGYG 162
Cdd:PRK09525   84 TIPVPSNWQLHGYDAPIYTNVTYPIPVNPPFVPEENPTGCYSLTFTVDESWLQSGQTRIIFDGVNSAFHLWCNGRWVGYS 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C        163 QDSRLPSEFDLSAFLRAGENRLAVMVLRWSDGSYLEDQDMWRMSGIFRDVSLLHKPTTQISDFHVATRFNDDFSRAVLEA 242
Cdd:PRK09525  164 QDSRLPAEFDLSPFLRAGENRLAVMVLRWSDGSYLEDQDMWRMSGIFRDVSLLHKPTTQLSDFHITTELDDDFRRAVLEV 243
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C        243 EVQMCGELRDYLRVTVSLWQGETQVASGTAPFGGEIIDERGGYADRVTLRLNVENPKLWSAEIPNLYRAVVELHTADGTL 322
Cdd:PRK09525  244 EAQVNGELRDELRVTVQLWDGETLVASGTAPFGTEIIDERGAYADRVTLRLNVENPKLWSAETPNLYRAVVSLLDADGTL 323
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C        323 IEAEACDVGFREVRIENGLLLLNGKPLLIRGVNRHEHHPLHGQVMDEQTMVQDILLMKQNNFNAVRCSHYPNHPLWYTLC 402
Cdd:PRK09525  324 IEAEAYDVGFRKVEIENGLLKLNGKPLLIRGVNRHEHHPEHGQVMDEETMVQDILLMKQHNFNAVRCSHYPNHPLWYELC 403
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C        403 DRYGLYVVDEANIETHGMVPMNRLTDDPRWLPAMSERVTRMVQRDRNHPSVIIWSLGNESGHGANHDALYRWIKSVDPSR 482
Cdd:PRK09525  404 DRYGLYVVDEANIETHGMVPMNRLSDDPRWLPAMSERVTRMVQRDRNHPSIIIWSLGNESGHGANHDALYRWIKSNDPSR 483
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C        483 PVQYEGGGADTTATDIICPMYARVDEDQPFPAVPKWSIKKWLSLPGETRPLILCEYAHAMGNSLGGFAKYWQAFRQYPRL 562
Cdd:PRK09525  484 PVQYEGGGADTAATDIICPMYARVDEDQPFPAVPKWSIKKWISLPGETRPLILCEYAHAMGNSLGGFAKYWQAFRQYPRL 563
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C        563 QGGFVWDWVDQSLIKYDENGNPWSAYGGDFGDTPNDRQFCMNGLVFADRTPHPALTEAKHQQQFFQFRL---SGQTIEVT 639
Cdd:PRK09525  564 QGGFIWDWVDQGLTKYDENGNPWWAYGGDFGDTPNDRQFCMNGLVFPDRTPHPALYEAKHAQQFFQFSLlstTPLTIEVT 643
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C        640 SEYLFRHSDNELLHWMVALDGKPLASGEVPLDVAPQGKQLIELPELPQPESAGQLWLTVRVVQPNATAWSEAGHISAWQQ 719
Cdd:PRK09525  644 SEYLFRHSDNELLHWSVALDGKPLASGEVPLDLAPQGSQRITLPELPQPESAGQLWLNVEVVQPNATAWSEAGHRSAWQQ 723
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C        720 WRLAENLSVTLPAASHAIPHLTTSEMDFCIELGNKRWQFNRQSGFLSQMWIGDKKQLLTPLRDQFTRAPLDNDIGVSEAT 799
Cdd:PRK09525  724 WRLPEPLSLPLPTASHAAPQLTQDEQDFCIELGNQRWQFNRQSGLLSQWWVGGKEQLLTPLRDQFTRAPLDNDIGVSEAT 803
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C        800 RIDPNAWVERWKAAGHYQAEAALLQCTADTLADAVLITTAHAWQHQGKTLFISRKTYRIDGSGQMAITVDVEVASDTPHP 879
Cdd:PRK09525  804 RIDPNAWVERWKAAGLYQLEARLLQCDADTLADAVLITTEHAYQHQGKTLFISRKTYRIDGQGEMTIDVDVEVASDLPPP 883
                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C        880 ARIGLNCQLAQVAERVNWLGLGPQENYPDRLTAACFDRWDLPLSDMYTPYVFPSENGLRCGTRELNYGPHQWRGDFQFNI 959
Cdd:PRK09525  884 ARIGLTCQLAQVAERVSWLGLGPHENYPDRLLAACFGRWDLPLSDMHTPYIFPSENGLRCGTRELNYGRHQIRGDFHFNI 963
                         970       980       990      1000      1010      1020
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
1JZ5_C        960 SRYSQQQLMETSHRHLLHAEEGTWLNIDGFHMGIGGDDSWSPSVSAEFQLSAGRYHYQLVWCQK 1023
Cdd:PRK09525  964 SRYSQQQLMETSHRHLLQAEEGTWLNIDGFHMGVGGDDSWSPSVHPEFLLSAGRYHYQLTWCQK 1027
LacZ COG3250
Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism];
56-629 2.68e-180

Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism];


Pssm-ID: 442481 [Multi-domain]  Cd Length: 638  Bit Score: 538.96  E-value: 2.68e-180
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C        56 GEWRFAWFPAPEAVPESWlecDLPEADTVVVPSNWQMHGYDAPiytnvtypitvnPPFVPT---ENPTGCYSLTFNVDES 132
Cdd:COG3250    1 GGWKFRLGDAPEGAKPDF---DDSGWDPITVPGDWELDLYGLP------------DPFVGPwylYNGVGWYRRTFTVPAS 65
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C       133 WlQEGQTRIIFDGVNSAFHLWCNGRWVGYGQDSRLPSEFDLSAFLRAGENRLAVMVLRWSDGSYLEDQDMWRMSGIFRDV 212
Cdd:COG3250   66 W-KGKRVFLHFEGVDTAAEVWVNGKKVGYHEGGFTPFEFDITDYLKPGENVLAVRVDNPSDGSYLEGQDWWRTSGIYRDV 144
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C       213 SLLHKPTTQISDFHVATRFNDDfsRAVLEAEVQMCGELRDYLRVTVSLW-QGETQVASGTAPfggeiIDERGGYADRVTL 291
Cdd:COG3250  145 WLEATPKVHIEDVFVTPDLDDG--SATLTVEVELENESDAGVTVEVTLLdADGKVVATATAK-----VTLAAGEENTVTL 217
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C       292 RLNVENPKLWSAEIPNLYRAVVELhTADGTLIEAEACDVGFREVRIE-------NGllllngKPLLIRGVNRHEHHPLHG 364
Cdd:COG3250  218 TLTVPNPKLWSPEDPNLYTLVVTL-KDDGKVVDTVSTRFGFRTIEIDgdggfllNG------KPVFLKGVNRHEDWPDDG 290
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C       365 QVMDEQTMVQDILLMKQNNFNAVRCSHYPNHPLWYTLCDRYGLYVVDEANIETHGMvpmnrLTDDPRWLPAMSERVTRMV 444
Cdd:COG3250  291 RAVTDEAMRRDLELMKEAGFNAVRTSHYPEDPEFYDLCDELGLLVWDEAPFEWHGM-----LGDDPEFLEAVEAELREMV 365
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C       445 QRDRNHPSVIIWSLGNESGHGANHDALYRWIKSVDPSRPVqyegggadttatdiicpmyarvdedqpfpavpkwsikkwl 524
Cdd:COG3250  366 RRDRNHPSIILWSGGNESGGGPNFAALYEWVKELDPTRPV---------------------------------------- 405
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C       525 slpgetrpLILCEYAHAMGNSLGG----------------FAKYWQAFRQYPRLQGGFVWDWVDQSLIKydengnpwsay 588
Cdd:COG3250  406 --------RFLSEYGHAMPNSLGGgyhqpsdfeeyqalqaLEEYWEAFRRRPRLAGGFIWQLNDYWPEP----------- 466
                        570       580       590       600
                 ....*....|....*....|....*....|....*....|..
1JZ5_C       589 ggdfgdTPNDRQFCMNGLVFA-DRTPHPALTEAKHQQQFFQF 629
Cdd:COG3250  467 ------RDNDGNFCSWGLVDYyDRTPKPAYYEVKSAWQPVLV 502
Glyco_hydro_2_C pfam02836
Glycosyl hydrolases family 2, TIM barrel domain; This family contains beta-galactosidase, ...
335-629 6.17e-152

Glycosyl hydrolases family 2, TIM barrel domain; This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities.


Pssm-ID: 397119 [Multi-domain]  Cd Length: 302  Bit Score: 452.67  E-value: 6.17e-152
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C         335 VRIENGLLLLNGKPLLIRGVNRHEHHPLHGQVMDEQTMVQDILLMKQNNFNAVRCSHYPNHPLWYTLCDRYGLYVVDEAN 414
Cdd:pfam02836    1 VEVKDGLFLINGKPFYFRGVNRHEDHDRRGRGFDMDLMVKDIQLMKQNNINAVRTSHYPNHPEWYQLCDEYGIYVIDEAN 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C         415 IETHGMVPM--------NRLTDDPRWLPAMSERVTRMVQRDRNHPSVIIWSLGNESGHGANHDALYRWIKSVDPSRPVQY 486
Cdd:pfam02836   81 LETHGLWQKfgeiepsySELTDNPEWLPAHLERAEELVQRDKNHPSVIIWSLGNESGAGENIAAMYAATKSLDPTRPVHY 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C         487 EGGGADTTATDIICPMYARVDEDQPFPAVpkwsIKKWLSLP--GETRPLILCEYAHAMGNSLGGFAKYWQAFRQYPRLQG 564
Cdd:pfam02836  161 EGVGIDPEVDDIILDIYSRMYEDYGHPEV----IEKYLEDWykKPQKPIIICEYGHAMGNSPGGLQEYQDLFYKYPEYQG 236
                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
1JZ5_C         565 GFVWDWVDQSLIKYDEN-GNPWSAYGGDFGDTPNDRQFCMNGLVFADRTPHPALTEAKHQQQFFQF 629
Cdd:pfam02836  237 GFIWDWHDQGIQKRDPNvGGEWYWYGGDFGDRPSDYRFCGNGLFFADRTPKPALFELKKRYWPIKI 302
Bgal_small_N smart01038
Beta galactosidase small chain; This domain comprises the small chain of dimeric ...
752-1020 1.33e-99

Beta galactosidase small chain; This domain comprises the small chain of dimeric beta-galactosidases EC:3.2.1.23. This domain is also found in single chain beta-galactosidase.


Pssm-ID: 214988 [Multi-domain]  Cd Length: 272  Bit Score: 314.52  E-value: 1.33e-99
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C          752 GNKRWQFNRQSGFLSQMWIGDKKQLLTPLRDQFTRAPLDNDIGVSeatridPNAWVERWKAAGHYQAEAALLQCTADTLA 831
Cdd:smart01038    3 GGFSYTFDKATGALTSWTYNGKELLLRGPKPNFWRAPTDNDRGNG------PNAWAARWKAAGLDRLTTRVRSVEVEQDS 76
                            90       100       110       120       130       140       150       160
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C          832 DAVLITTAHAWQHQGKtLFISRKTYRIDGSGQMAITVDVEVASDTPHP-ARIGLNCQLAQVAERVNWLGLGPQENYPDRL 910
Cdd:smart01038   77 DVVVTVEYLLAAPSGW-GFTVTVTYTIDGDGEVKVDVTFTPGGGALPDlPRIGLRFRLPDELEQVEWYGRGPGENYPDRK 155
                           170       180       190       200       210       220       230       240
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C          911 TAACFDRWDLPLSDMYTPYVFPSENGLRCGTRELNYGPHQWRG-------DFQFNISRYSQQQLMETSHRHLLHAEEGTW 983
Cdd:smart01038  156 QSARLGRYSSTVDDLFTPYVRPQENGNRTDVRWLTLTDDAGNGlrvtadqPFSFSALPYSAEDLEEAKHPHELPPRDGTV 235
                           250       260       270
                    ....*....|....*....|....*....|....*..
1JZ5_C          984 LNIDGFHMGIGGDDSWSPSVSAEFQLSAGRYHYQLVW 1020
Cdd:smart01038  236 LNLDAKQMGVGGDDSWGPGVLPEYRLPADEYSFSFTL 272
 
Name Accession Description Interval E-value
lacZ PRK09525
beta-galactosidase;
3-1023 0e+00

beta-galactosidase;


Pssm-ID: 236548 [Multi-domain]  Cd Length: 1027  Bit Score: 2185.48  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C          3 HMLEDPVVLQRRDWENPGVTQLNRLAAHPPFASWRNSEEARTDRPSQQLRSLNGEWRFAWFPAPEAVPESWLECDLPEAD 82
Cdd:PRK09525    4 IMDSLAQILARRDWENPGVTQLNRLPAHPPFASWRNSEAARDDRPSQQRQSLNGEWRFSYFPAPEAVPESWLECDLPDAD 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C         83 TVVVPSNWQMHGYDAPIYTNVTYPITVNPPFVPTENPTGCYSLTFNVDESWLQEGQTRIIFDGVNSAFHLWCNGRWVGYG 162
Cdd:PRK09525   84 TIPVPSNWQLHGYDAPIYTNVTYPIPVNPPFVPEENPTGCYSLTFTVDESWLQSGQTRIIFDGVNSAFHLWCNGRWVGYS 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C        163 QDSRLPSEFDLSAFLRAGENRLAVMVLRWSDGSYLEDQDMWRMSGIFRDVSLLHKPTTQISDFHVATRFNDDFSRAVLEA 242
Cdd:PRK09525  164 QDSRLPAEFDLSPFLRAGENRLAVMVLRWSDGSYLEDQDMWRMSGIFRDVSLLHKPTTQLSDFHITTELDDDFRRAVLEV 243
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C        243 EVQMCGELRDYLRVTVSLWQGETQVASGTAPFGGEIIDERGGYADRVTLRLNVENPKLWSAEIPNLYRAVVELHTADGTL 322
Cdd:PRK09525  244 EAQVNGELRDELRVTVQLWDGETLVASGTAPFGTEIIDERGAYADRVTLRLNVENPKLWSAETPNLYRAVVSLLDADGTL 323
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C        323 IEAEACDVGFREVRIENGLLLLNGKPLLIRGVNRHEHHPLHGQVMDEQTMVQDILLMKQNNFNAVRCSHYPNHPLWYTLC 402
Cdd:PRK09525  324 IEAEAYDVGFRKVEIENGLLKLNGKPLLIRGVNRHEHHPEHGQVMDEETMVQDILLMKQHNFNAVRCSHYPNHPLWYELC 403
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C        403 DRYGLYVVDEANIETHGMVPMNRLTDDPRWLPAMSERVTRMVQRDRNHPSVIIWSLGNESGHGANHDALYRWIKSVDPSR 482
Cdd:PRK09525  404 DRYGLYVVDEANIETHGMVPMNRLSDDPRWLPAMSERVTRMVQRDRNHPSIIIWSLGNESGHGANHDALYRWIKSNDPSR 483
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C        483 PVQYEGGGADTTATDIICPMYARVDEDQPFPAVPKWSIKKWLSLPGETRPLILCEYAHAMGNSLGGFAKYWQAFRQYPRL 562
Cdd:PRK09525  484 PVQYEGGGADTAATDIICPMYARVDEDQPFPAVPKWSIKKWISLPGETRPLILCEYAHAMGNSLGGFAKYWQAFRQYPRL 563
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C        563 QGGFVWDWVDQSLIKYDENGNPWSAYGGDFGDTPNDRQFCMNGLVFADRTPHPALTEAKHQQQFFQFRL---SGQTIEVT 639
Cdd:PRK09525  564 QGGFIWDWVDQGLTKYDENGNPWWAYGGDFGDTPNDRQFCMNGLVFPDRTPHPALYEAKHAQQFFQFSLlstTPLTIEVT 643
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C        640 SEYLFRHSDNELLHWMVALDGKPLASGEVPLDVAPQGKQLIELPELPQPESAGQLWLTVRVVQPNATAWSEAGHISAWQQ 719
Cdd:PRK09525  644 SEYLFRHSDNELLHWSVALDGKPLASGEVPLDLAPQGSQRITLPELPQPESAGQLWLNVEVVQPNATAWSEAGHRSAWQQ 723
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C        720 WRLAENLSVTLPAASHAIPHLTTSEMDFCIELGNKRWQFNRQSGFLSQMWIGDKKQLLTPLRDQFTRAPLDNDIGVSEAT 799
Cdd:PRK09525  724 WRLPEPLSLPLPTASHAAPQLTQDEQDFCIELGNQRWQFNRQSGLLSQWWVGGKEQLLTPLRDQFTRAPLDNDIGVSEAT 803
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C        800 RIDPNAWVERWKAAGHYQAEAALLQCTADTLADAVLITTAHAWQHQGKTLFISRKTYRIDGSGQMAITVDVEVASDTPHP 879
Cdd:PRK09525  804 RIDPNAWVERWKAAGLYQLEARLLQCDADTLADAVLITTEHAYQHQGKTLFISRKTYRIDGQGEMTIDVDVEVASDLPPP 883
                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C        880 ARIGLNCQLAQVAERVNWLGLGPQENYPDRLTAACFDRWDLPLSDMYTPYVFPSENGLRCGTRELNYGPHQWRGDFQFNI 959
Cdd:PRK09525  884 ARIGLTCQLAQVAERVSWLGLGPHENYPDRLLAACFGRWDLPLSDMHTPYIFPSENGLRCGTRELNYGRHQIRGDFHFNI 963
                         970       980       990      1000      1010      1020
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
1JZ5_C        960 SRYSQQQLMETSHRHLLHAEEGTWLNIDGFHMGIGGDDSWSPSVSAEFQLSAGRYHYQLVWCQK 1023
Cdd:PRK09525  964 SRYSQQQLMETSHRHLLQAEEGTWLNIDGFHMGVGGDDSWSPSVHPEFLLSAGRYHYQLTWCQK 1027
ebgA PRK10340
cryptic beta-D-galactosidase subunit alpha; Reviewed
16-1003 0e+00

cryptic beta-D-galactosidase subunit alpha; Reviewed


Pssm-ID: 236673 [Multi-domain]  Cd Length: 1021  Bit Score: 762.29  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C         16 WENPGVTQLNRLAAHPPFASWRNSEEARTDRP--SQQLRSLNGEWRFAWFPAPEAVPESWLECDLPEADTVVVPSNWQMH 93
Cdd:PRK10340    4 WENIQLTHENRLAPRAYFFSYDSVAQARTFARetSSLFLLLSGQWNFHFFDHPLYVPEAFTSELMSDWGHITVPAMWQME 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C         94 GYDAPIYTNVTYPITVNPPFVPTENPTGCYSLTFNVDESWLQEgQTRIIFDGVNSAFHLWCNGRWVGYGQDSRLPSEFDL 173
Cdd:PRK10340   84 GHGKLQYTDEGFPFPIDVPFVPSDNPTGAYQRTFTLSDGWQGK-QTIIKFDGVETYFEVYVNGQYVGFSKGSRLTAEFDI 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C        174 SAFLRAGENRLAVMVLRWSDGSYLEDQDMWRMSGIFRDVSLLHKPTTQISDFHVATRFNDDFSRAVLEAEVQM--CGELR 251
Cdd:PRK10340  163 SAMVKTGDNLLCVRVMQWADSTYLEDQDMWWLAGIFRDVYLVGKPLTHINDFTVRTDFDEDYCDATLSCEVVLenLAASP 242
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C        252 DYLRVTVSLWQGETQVASGTApfGGEIIDERGGyadrVTLRLNVENPKLWSAEIPNLYRAVVELHTADGTLIEAEACDVG 331
Cdd:PRK10340  243 VVTTLEYTLFDGERVVHSSAI--DHLAIEKLTS----ASFAFTVEQPQQWSAESPYLYHLVMTLKDANGNVLEVVPQRVG 316
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C        332 FREVRIENGLLLLNGKPLLIRGVNRHEHHPLHGQVMDEQTMVQDILLMKQNNFNAVRCSHYPNHPLWYTLCDRYGLYVVD 411
Cdd:PRK10340  317 FRDIKVRDGLFWINNRYVKLHGVNRHDNDHRKGRAVGMDRVEKDIQLMKQHNINSVRTAHYPNDPRFYELCDIYGLFVMA 396
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C        412 EANIETHGMV---PMNRLTDDPRWLPAMSERVTRMVQRDRNHPSVIIWSLGNESGHGANHDALYRWIKSVDPSRPVQYEg 488
Cdd:PRK10340  397 ETDVESHGFAnvgDISRITDDPQWEKVYVDRIVRHIHAQKNHPSIIIWSLGNESGYGCNIRAMYHAAKALDDTRLVHYE- 475
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C        489 GGADTTATDIICPMYARVDEDQPFPAVPKwsikkwlslpgeTRPLILCEYAHAMGNSLGGFAKYWQAFRQYPRLQGGFVW 568
Cdd:PRK10340  476 EDRDAEVVDVISTMYTRVELMNEFGEYPH------------PKPRILCEYAHAMGNGPGGLTEYQNVFYKHDCIQGHYVW 543
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C        569 DWVDQSLIKYDENGNPWSAYGGDFGDTPNDRQFCMNGLVFADRTPHPALTEAKHQQQFFQFR---LSGQTIEVTSEYLFR 645
Cdd:PRK10340  544 EWCDHGIQAQDDNGNVWYKYGGDYGDYPNNYNFCIDGLIYPDQTPGPGLKEYKQVIAPVKIHaldLTRGELKVENKLWFT 623
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C        646 HSDNELLHWMVALDGKPLASGEVPL-DVAPQGKQLIELpELPQPESAgQLWLTVRVVQPNATAWSEAGHISAWQQWRLAE 724
Cdd:PRK10340  624 NLDDYTLHAEVRAEGETLASGQIKLrDVAPNSEAPLQI-TLPQLDAR-EAFLNITVTKDSRTRYSEAGHSIATYQFPLKE 701
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C        725 NLSVTLPAASHAIPHLTTSE--MDFCIELGNKRWQFNRQSGFLSQMWIGDKKQLLTPLRDQFTRAPLDNDIGVSEATrID 802
Cdd:PRK10340  702 NTAQPVPFAPNNARPLTLEEdrLSCTVRGYNFAITFSKVSGKLTSWQVNGESLLTREPKINFFKPMIDNHKQEYEGL-WQ 780
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C        803 P---NAWVERWKAAGHYQAEAALLQCTADTLAdavliTTAHAWQHQgktlfiSRKTYRIDGSGQMAITVDVEVASDTPH- 878
Cdd:PRK10340  781 PnhlQIMQEHLRDFAVEQSDGEVLIISRTVIA-----PPVFDFGMR------CTYIYRIAADGQVNVALSGERYGDYPHm 849
                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C        879 -PaRIGLNCQLAQVAERVNWLGLGPQENYPDRLTAACFDRWDLPLSDMYTPYVFPSENGLRCGTRELNYGPHQWRG---- 953
Cdd:PRK10340  850 iP-CIGFTMGINGEYDQVAYYGRGPGENYADSQQANLIDIYRSTVDAMFENYPFPQNNGNRQHVRWTALTNRHGNGllvv 928
                         970       980       990      1000      1010
                  ....*....|....*....|....*....|....*....|....*....|...
1JZ5_C        954 ---DFQFNISRYSQQQLMETSHRHLLHAEEGTWLNIDGFHMGIgGDDSWSPSV 1003
Cdd:PRK10340  929 pqrPINFSAWHYTQENIHAAQHTNELQKSDYITLNLDHQLLGL-GSNSWGSEV 980
LacZ COG3250
Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism];
56-629 2.68e-180

Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism];


Pssm-ID: 442481 [Multi-domain]  Cd Length: 638  Bit Score: 538.96  E-value: 2.68e-180
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C        56 GEWRFAWFPAPEAVPESWlecDLPEADTVVVPSNWQMHGYDAPiytnvtypitvnPPFVPT---ENPTGCYSLTFNVDES 132
Cdd:COG3250    1 GGWKFRLGDAPEGAKPDF---DDSGWDPITVPGDWELDLYGLP------------DPFVGPwylYNGVGWYRRTFTVPAS 65
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C       133 WlQEGQTRIIFDGVNSAFHLWCNGRWVGYGQDSRLPSEFDLSAFLRAGENRLAVMVLRWSDGSYLEDQDMWRMSGIFRDV 212
Cdd:COG3250   66 W-KGKRVFLHFEGVDTAAEVWVNGKKVGYHEGGFTPFEFDITDYLKPGENVLAVRVDNPSDGSYLEGQDWWRTSGIYRDV 144
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C       213 SLLHKPTTQISDFHVATRFNDDfsRAVLEAEVQMCGELRDYLRVTVSLW-QGETQVASGTAPfggeiIDERGGYADRVTL 291
Cdd:COG3250  145 WLEATPKVHIEDVFVTPDLDDG--SATLTVEVELENESDAGVTVEVTLLdADGKVVATATAK-----VTLAAGEENTVTL 217
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C       292 RLNVENPKLWSAEIPNLYRAVVELhTADGTLIEAEACDVGFREVRIE-------NGllllngKPLLIRGVNRHEHHPLHG 364
Cdd:COG3250  218 TLTVPNPKLWSPEDPNLYTLVVTL-KDDGKVVDTVSTRFGFRTIEIDgdggfllNG------KPVFLKGVNRHEDWPDDG 290
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C       365 QVMDEQTMVQDILLMKQNNFNAVRCSHYPNHPLWYTLCDRYGLYVVDEANIETHGMvpmnrLTDDPRWLPAMSERVTRMV 444
Cdd:COG3250  291 RAVTDEAMRRDLELMKEAGFNAVRTSHYPEDPEFYDLCDELGLLVWDEAPFEWHGM-----LGDDPEFLEAVEAELREMV 365
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C       445 QRDRNHPSVIIWSLGNESGHGANHDALYRWIKSVDPSRPVqyegggadttatdiicpmyarvdedqpfpavpkwsikkwl 524
Cdd:COG3250  366 RRDRNHPSIILWSGGNESGGGPNFAALYEWVKELDPTRPV---------------------------------------- 405
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C       525 slpgetrpLILCEYAHAMGNSLGG----------------FAKYWQAFRQYPRLQGGFVWDWVDQSLIKydengnpwsay 588
Cdd:COG3250  406 --------RFLSEYGHAMPNSLGGgyhqpsdfeeyqalqaLEEYWEAFRRRPRLAGGFIWQLNDYWPEP----------- 466
                        570       580       590       600
                 ....*....|....*....|....*....|....*....|..
1JZ5_C       589 ggdfgdTPNDRQFCMNGLVFA-DRTPHPALTEAKHQQQFFQF 629
Cdd:COG3250  467 ------RDNDGNFCSWGLVDYyDRTPKPAYYEVKSAWQPVLV 502
Glyco_hydro_2_C pfam02836
Glycosyl hydrolases family 2, TIM barrel domain; This family contains beta-galactosidase, ...
335-629 6.17e-152

Glycosyl hydrolases family 2, TIM barrel domain; This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities.


Pssm-ID: 397119 [Multi-domain]  Cd Length: 302  Bit Score: 452.67  E-value: 6.17e-152
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C         335 VRIENGLLLLNGKPLLIRGVNRHEHHPLHGQVMDEQTMVQDILLMKQNNFNAVRCSHYPNHPLWYTLCDRYGLYVVDEAN 414
Cdd:pfam02836    1 VEVKDGLFLINGKPFYFRGVNRHEDHDRRGRGFDMDLMVKDIQLMKQNNINAVRTSHYPNHPEWYQLCDEYGIYVIDEAN 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C         415 IETHGMVPM--------NRLTDDPRWLPAMSERVTRMVQRDRNHPSVIIWSLGNESGHGANHDALYRWIKSVDPSRPVQY 486
Cdd:pfam02836   81 LETHGLWQKfgeiepsySELTDNPEWLPAHLERAEELVQRDKNHPSVIIWSLGNESGAGENIAAMYAATKSLDPTRPVHY 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C         487 EGGGADTTATDIICPMYARVDEDQPFPAVpkwsIKKWLSLP--GETRPLILCEYAHAMGNSLGGFAKYWQAFRQYPRLQG 564
Cdd:pfam02836  161 EGVGIDPEVDDIILDIYSRMYEDYGHPEV----IEKYLEDWykKPQKPIIICEYGHAMGNSPGGLQEYQDLFYKYPEYQG 236
                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
1JZ5_C         565 GFVWDWVDQSLIKYDEN-GNPWSAYGGDFGDTPNDRQFCMNGLVFADRTPHPALTEAKHQQQFFQF 629
Cdd:pfam02836  237 GFIWDWHDQGIQKRDPNvGGEWYWYGGDFGDRPSDYRFCGNGLFFADRTPKPALFELKKRYWPIKI 302
Bgal_small_N smart01038
Beta galactosidase small chain; This domain comprises the small chain of dimeric ...
752-1020 1.33e-99

Beta galactosidase small chain; This domain comprises the small chain of dimeric beta-galactosidases EC:3.2.1.23. This domain is also found in single chain beta-galactosidase.


Pssm-ID: 214988 [Multi-domain]  Cd Length: 272  Bit Score: 314.52  E-value: 1.33e-99
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C          752 GNKRWQFNRQSGFLSQMWIGDKKQLLTPLRDQFTRAPLDNDIGVSeatridPNAWVERWKAAGHYQAEAALLQCTADTLA 831
Cdd:smart01038    3 GGFSYTFDKATGALTSWTYNGKELLLRGPKPNFWRAPTDNDRGNG------PNAWAARWKAAGLDRLTTRVRSVEVEQDS 76
                            90       100       110       120       130       140       150       160
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C          832 DAVLITTAHAWQHQGKtLFISRKTYRIDGSGQMAITVDVEVASDTPHP-ARIGLNCQLAQVAERVNWLGLGPQENYPDRL 910
Cdd:smart01038   77 DVVVTVEYLLAAPSGW-GFTVTVTYTIDGDGEVKVDVTFTPGGGALPDlPRIGLRFRLPDELEQVEWYGRGPGENYPDRK 155
                           170       180       190       200       210       220       230       240
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C          911 TAACFDRWDLPLSDMYTPYVFPSENGLRCGTRELNYGPHQWRG-------DFQFNISRYSQQQLMETSHRHLLHAEEGTW 983
Cdd:smart01038  156 QSARLGRYSSTVDDLFTPYVRPQENGNRTDVRWLTLTDDAGNGlrvtadqPFSFSALPYSAEDLEEAKHPHELPPRDGTV 235
                           250       260       270
                    ....*....|....*....|....*....|....*..
1JZ5_C          984 LNIDGFHMGIGGDDSWSPSVSAEFQLSAGRYHYQLVW 1020
Cdd:smart01038  236 LNLDAKQMGVGGDDSWGPGVLPEYRLPADEYSFSFTL 272
Glyco_hydro_2_N pfam02837
Glycosyl hydrolases family 2, sugar binding domain; This family contains beta-galactosidase, ...
51-218 4.01e-84

Glycosyl hydrolases family 2, sugar binding domain; This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities and has a jelly-roll fold. The domain binds the sugar moiety during the sugar-hydrolysis reaction.


Pssm-ID: 397120 [Multi-domain]  Cd Length: 169  Bit Score: 268.73  E-value: 4.01e-84
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C          51 LRSLNGEWRFAWFPAPEAVPESWLECDLPEADTVVVPSNWQMHgydaPIYTNVTYPITVNPPFVPTENPTGCYSLTFNVD 130
Cdd:pfam02837    1 IKSLNGEWAFALFDAPCGAPQSWWESALQESRTIAVPSSWNDQ----PIYTNVEYPIDFADPFIPTYNGTGWYQRTFFIP 76
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C         131 ESWLQEgQTRIIFDGVNSAFHLWCNGRWVGYGQDSRLPSEFDLSAFLRAGENRLAVMVLRWSDGSYLEDQ------DMWR 204
Cdd:pfam02837   77 SKWAGQ-RIRLRFDGVTHYGEVWVNGQWVGEHQGGYTPFEFDLTPYVIAGKNRIAVKVLNWSDG*YIEDQngkyfhDFWN 155
                          170
                   ....*....|....
1JZ5_C         205 MSGIFRDVSLLHKP 218
Cdd:pfam02837  156 YSGIYRDVSLLTTP 169
Bgal_small_N pfam02929
Beta galactosidase small chain; This domain comprises the small chain of dimeric ...
752-1020 1.92e-60

Beta galactosidase small chain; This domain comprises the small chain of dimeric beta-galactosidases EC:3.2.1.23. This domain is also found in single chain beta-galactosidase.


Pssm-ID: 460751  Cd Length: 223  Bit Score: 205.80  E-value: 1.92e-60
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C         752 GNKRWQFNRQSGFLSQMWIGDKKQLLTPL--RDQFTRAPLDNDIGVseatridpnawverwkaaghyqaeaallqctadt 829
Cdd:pfam02929    3 GDFSYTFDKATGTLTSYKYDGKELLTEPLtgRPNFWRAPTDNDVTV---------------------------------- 48
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C         830 ladavlittahawqhqgktlfisrkTYRIDGSGQMAITVDVEVAS--DTPHPARIGLNCQLAQVAERVNWLGLGPQENYP 907
Cdd:pfam02929   49 -------------------------TYTIYGDGTIKVDVTLKPDGlkGLPELPRFGLRLQLPKSFEQVEWYGRGPGENYP 103
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C         908 DRLTAACFDRWDLPLSDMYTPYVFPSENGLRCGTRELNYGPHQWRG--------DFQFNISRYSQQQLMETSHRHLLHAE 979
Cdd:pfam02929  104 DRKTGARLGIYESTVDDLFTPYIRPQENGNRTDVRWLTLTDGDGGGllvfvgdgPFSFSALPYTPEELEAAKHPYELPKS 183
                          250       260       270       280
                   ....*....|....*....|....*....|....*....|.
1JZ5_C         980 EGTWLNIDGFHMGIgGDDSWSPSVSAEFQLSAGRYHYQLVW 1020
Cdd:pfam02929  184 DETVLNLDYAQMGV-GDNSWGPGVLPEYRLPAKEYSFSFTL 223
PRK10150 PRK10150
beta-D-glucuronidase; Provisional
44-510 3.11e-45

beta-D-glucuronidase; Provisional


Pssm-ID: 236657 [Multi-domain]  Cd Length: 604  Bit Score: 173.27  E-value: 3.11e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C         44 TDRPSQQLRSLNGEWRFAWFPAPEAVPESWLECDLPEADTVVVPSNWQMHGYDAPIYTNVTYPItvnppfvptenptgcY 123
Cdd:PRK10150    5 VETKTREIKDLSGLWAFKLDRENCGIDQRWWESALPESRAMAVPGSFNDQFADADIRNYVGDVW---------------Y 69
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C        124 SLTFNVDESWLQEgqtRII--FDGVNSAFHLWCNGRWVGYGQDSRLPSEFDLSAFLRAGEN-RLAVMV---LRWSD---G 194
Cdd:PRK10150   70 QREVFIPKGWAGQ---RIVlrFGSVTHYAKVWVNGQEVMEHKGGYTPFEADITPYVYAGKSvRITVCVnneLNWQTlppG 146
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C        195 SYLEDQ----------DMWRMSGIFRDVSLLHKPTTQISDFHVATRFNDDFSRAVLEAEVQMCGElRDYLRVTvslwqge 264
Cdd:PRK10150  147 NVIEDGngkkkqkynfDFFNYAGIHRPVMLYTTPKTHIDDITVVTELAQDLNHASVDWSVETNGD-VDSVSVT------- 218
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C        265 tqvasgtapfggeIIDERG---GYADRVTLRLNVENPKLWSAEIPNLYRAVVELhTADGTLIEAEACDVGFREVRIENGL 341
Cdd:PRK10150  219 -------------LRDADGqvvATGQGTSGTLQVVNPHLWQPGEGYLYTLCVEL-AKSGTECDTYPLRFGIRSVAVKGGQ 284
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C        342 LLLNGKPLLIRGVNRHEHHPLHGQVMDEQTMVQDILLMKQNNFNAVRCSHYPNHPLWYTLCDRYGLYVVDEA-------- 413
Cdd:PRK10150  285 FLINGKPFYFKGFGKHEDADIRGKGLDEVLNVHDHNLMKWIGANSFRTSHYPYSEEMLDLADRHGIVVIDETpavglnls 364
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C        414 ----------NIETHGMVPMNRLTDDPRwLPAMSErvtrMVQRDRNHPSVIIWSLGNESghgANHDA--------LYRWI 475
Cdd:PRK10150  365 fgagleagnkPKETYSEEAVNGETQQAH-LQAIRE----LIARDKNHPSVVMWSIANEP---ASREQgareyfapLAELT 436
                         490       500       510
                  ....*....|....*....|....*....|....*
1JZ5_C        476 KSVDPSRPVqyegggadtTATDIicpMYARVDEDQ 510
Cdd:PRK10150  437 RKLDPTRPV---------TCVNV---MFATPDTDT 459
LacZ_4 pfam16353
Beta-galactosidase, domain 4; This entry represents domain 4 found in beta-galactosidase and ...
636-723 1.13e-24

Beta-galactosidase, domain 4; This entry represents domain 4 found in beta-galactosidase and it is organized in a jelly-roll type barrel (Rutkiewicz-Krotewicz M. et al. Crystals 2018, 8(1), 13, https://doi.org/10.3390/cryst8010013).


Pssm-ID: 465101 [Multi-domain]  Cd Length: 88  Bit Score: 98.80  E-value: 1.13e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C         636 IEVTSEYLFRHSDNELLHWMVALDGKPLASGEVP-LDVAPQGKQLIELPeLPQPESAGQLWLTVRVVQPNATAWSEAGHI 714
Cdd:pfam16353    1 VTITNRYDFTDLDDYDLSWELLADGKVVASGTLElPDVAPGESATVTLP-LPLPGLAGEYFLTVSFRLKEDTPWAPAGHE 79

                   ....*....
1JZ5_C         715 SAWQQWRLA 723
Cdd:pfam16353   80 VAWEQFPLP 88
Glyco_hydro_2 pfam00703
Glycosyl hydrolases family 2; This family contains beta-galactosidase, beta-mannosidase and ...
222-333 2.09e-13

Glycosyl hydrolases family 2; This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities.


Pssm-ID: 395572 [Multi-domain]  Cd Length: 106  Bit Score: 67.12  E-value: 2.09e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C         222 ISDFHVATRFNDDfSRAVLEAEVQMCGELRDYLRVTVSlwqgetqvASGTAPFGGEIIDERGGYADRV--TLRLNVENPK 299
Cdd:pfam00703    3 IEDVFITPDLDDD-KTAKVTVEVELENDGDASVEVTLE--------TEIKDADGKTVAAAAKVLVLGAgeTTELEVKNPK 73
                           90       100       110
                   ....*....|....*....|....*....|....
1JZ5_C         300 LWSAEIPNLYRAVVELhTADGTLIEAEACDVGFR 333
Cdd:pfam00703   74 LWSPETPNLYTLTVEL-DKDGKVIDEVSTRFGFR 106
LacZ COG3250
Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism];
918-1020 1.33e-06

Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism];


Pssm-ID: 442481 [Multi-domain]  Cd Length: 638  Bit Score: 52.45  E-value: 1.33e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JZ5_C       918 WDLPLSDMYTPYVFPSENGLRCGTRELNYGPHQWRGDFQFNISRYSQQQLMETSHRHLLHAEEGTWLNIDGFHMGIGGDD 997
Cdd:COG3250  524 YSSTVADLYTPYVRPQENGNRTDVRWLTLTNGKGKGLLVSGVPLLSGSALAYLTEDLLAAKEEGLLLAADLTTLLLDLAD 603
                         90       100
                 ....*....|....*....|...
1JZ5_C       998 SWSPSVSAEFQLSAGRYHYQLVW 1020
Cdd:COG3250  604 LGGGGNSGGGLLLLGGLLVEKDL 626
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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