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Conserved domains on  [gi|61679459|pdb|1Y63|A]
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Chain A, Lmaj004144AAA protein

Protein Classification

adenylate kinase family protein( domain architecture ID 1904751)

adenylate kinase family protein such as adenylate kinase isoenzyme 6 that has ATPase activity and is a broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates

CATH:  3.40.50.300
EC:  2.7.4.-
Gene Ontology:  GO:0005524|GO:0016887|GO:0050145
SCOP:  4004025

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Fap7 super family cl42788
Broad-specificity NMP kinase [Nucleotide transport and metabolism];
13-176 2.87e-35

Broad-specificity NMP kinase [Nucleotide transport and metabolism];


The actual alignment was detected with superfamily member COG1936:

Pssm-ID: 441539 [Multi-domain]  Cd Length: 173  Bit Score: 121.46  E-value: 2.87e-35
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1Y63_A       13 ILITGTPGTGKTSMAEMIAAELdGFQHLEVGKLVKENHFYTEYDTELDTHIIeekDEDRLLDFMEPImvSRGNHVVDYHS 92
Cdd:COG1936   3 IAITGTPGTGKTTVAKLLAERL-GLEVIHLNDLVKEEGLYTEVDEERDSLVV---DEDALAEELEEL--KEGDVIIEGHL 76

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1Y63_A       93 SELFPErwfHMVVVLHTSTEVLFERLTKRQYSEAKRAENMEAEIQCICEEEARDAYEDDIVLvrENDTLEQmaaTVEEIR 172
Cdd:COG1936  77 AHLVDV---DRVIVLRCNPEVLEERLEERGYSEEKIRENVEAEALDVILSEAVERFGEEKVY--EIDTTGR---TPEEVA 148


                ....
1Y63_A      173 ERVE 176
Cdd:COG1936 149 DEIL 152
 
Name Accession Description Interval E-value
Fap7 COG1936
Broad-specificity NMP kinase [Nucleotide transport and metabolism];
13-176 2.87e-35

Broad-specificity NMP kinase [Nucleotide transport and metabolism];


Pssm-ID: 441539 [Multi-domain]  Cd Length: 173  Bit Score: 121.46  E-value: 2.87e-35
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1Y63_A       13 ILITGTPGTGKTSMAEMIAAELdGFQHLEVGKLVKENHFYTEYDTELDTHIIeekDEDRLLDFMEPImvSRGNHVVDYHS 92
Cdd:COG1936   3 IAITGTPGTGKTTVAKLLAERL-GLEVIHLNDLVKEEGLYTEVDEERDSLVV---DEDALAEELEEL--KEGDVIIEGHL 76

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1Y63_A       93 SELFPErwfHMVVVLHTSTEVLFERLTKRQYSEAKRAENMEAEIQCICEEEARDAYEDDIVLvrENDTLEQmaaTVEEIR 172
Cdd:COG1936  77 AHLVDV---DRVIVLRCNPEVLEERLEERGYSEEKIRENVEAEALDVILSEAVERFGEEKVY--EIDTTGR---TPEEVA 148


                ....
1Y63_A      173 ERVE 176
Cdd:COG1936 149 DEIL 152
AAA_18 pfam13238
AAA domain;
13-136 2.91e-26

AAA domain;


Pssm-ID: 433052 [Multi-domain]  Cd Length: 128  Bit Score: 97.11  E-value: 2.91e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1Y63_A         13 ILITGTPGTGKTSMAEmIAAELDGFqHLEVGKLVKENHFYTEYDTELD-THIIEEKDEDRLLDFMEPI--MVSRGNHVVD 89
Cdd:pfam13238   1 ILITGTPGVGKTTLAK-ELSKRLGF-GDNVRDLALENGLVLGDDPETReSKRLDEDKLDRLLDLLEENaaLEEGGNLIID 78

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
1Y63_A         90 YHSSELFPERWF-HMVVVLHTSTEVLFERLTKRQYSEAKRAENMEAEI 136
Cdd:pfam13238  79 GHLAELEPERAKdLVGIVLRASPEELLERLEKRGYEEAKIKENEEAEI 126
PRK03839 PRK03839
putative kinase; Provisional
 13-176 2.87e-16

putative kinase; Provisional


Pssm-ID: 179660  Cd Length: 180  Bit Score: 72.45  E-value: 2.87e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1Y63_A        13 ILITGTPGTGKTSMAEMIAAELdGFQHLEVGKLVKENHFYTEYDTELDThiieekDEDRLLDFMEPIMVSRgNHVVDYHS 92
Cdd:PRK03839   3 IAITGTPGVGKTTVSKLLAEKL-GYEYVDLTEFALKKGIGEEKDDEMEI------DFDKLAYFIEEEFKEK-NVVLDGHL 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1Y63_A        93 SELFPErwfHMVVVLHTSTEVLFERLTKRQYSEAKRAENMEAEIQCICEEEARDAYEDDIVLVRENDTLEQMaatVEEIR 172
Cdd:PRK03839  75 SHLLPV---DYVIVLRAHPKIIKERLKERGYSKKKILENVEAELVDVCLCEALEEKEKVIEVDTTGKTPEEV---VEEIL 148


                 ....
1Y63_A       173 ERVE 176
Cdd:PRK03839 149 ELIK 152
AAA cd00009
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ...
 5-88 6.29e-05

The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.


Pssm-ID: 99707 [Multi-domain]  Cd Length: 151  Bit Score: 41.36  E-value: 6.29e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1Y63_A        5 MEQPKGINILITGTPGTGKTSMAEMIAAELdgfqhlevgKLVKENHFYTEYDTELDTHIIEEKDEDRLLDFMEPIMVSRG 84
Cdd:cd00009  14 LELPPPKNLLLYGPPGTGKTTLARAIANEL---------FRPGAPFLYLNASDLLEGLVVAELFGHFLVRLLFELAEKAK 84


                ....
1Y63_A       85 NHVV 88
Cdd:cd00009  85 PGVL 88
cyt_kin_arch TIGR02173
cytidylate kinase, putative; Proteins in this family are believed to be cytidylate kinase. ...
 13-122 9.44e-05

cytidylate kinase, putative; Proteins in this family are believed to be cytidylate kinase. Members of this family are found in the archaea and in spirochaetes, and differ considerably from the common bacterial form of cytidylate kinase described by TIGR00017.


Pssm-ID: 274012 [Multi-domain]  Cd Length: 171  Bit Score: 40.87  E-value: 9.44e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1Y63_A         13 ILITGTPGTGKTSMAEMIAAELdGFQHLEVGKL-----------VKENHFYTEYDTELDthiieeKDEDRLLdfmEPIMV 81
Cdd:TIGR02173   3 ITISGPPGSGKTTVAKILAEKL-SLKLISAGDIfrelaakmgldLIEFLNYAEENPEID------KKIDRRI---HEIAL 72

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
1Y63_A         82 SRGNHVVDYHSSELFPERWFHMVVVLHTSTEVLFERLTKRQ 122
Cdd:TIGR02173  73 KEKNVVLESRLAGWIVREYADVKIWLKAPLEVRARRIAKRE 113
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 9-35 8.21e-04

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 38.12  E-value: 8.21e-04
                           10        20
                   ....*....|....*....|....*..
1Y63_A           9 KGINILITGTPGTGKTSMAEMIAAELD 35
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELG 27
 
Name Accession Description Interval E-value
Fap7 COG1936
Broad-specificity NMP kinase [Nucleotide transport and metabolism];
13-176 2.87e-35

Broad-specificity NMP kinase [Nucleotide transport and metabolism];


Pssm-ID: 441539 [Multi-domain]  Cd Length: 173  Bit Score: 121.46  E-value: 2.87e-35
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1Y63_A       13 ILITGTPGTGKTSMAEMIAAELdGFQHLEVGKLVKENHFYTEYDTELDTHIIeekDEDRLLDFMEPImvSRGNHVVDYHS 92
Cdd:COG1936   3 IAITGTPGTGKTTVAKLLAERL-GLEVIHLNDLVKEEGLYTEVDEERDSLVV---DEDALAEELEEL--KEGDVIIEGHL 76

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1Y63_A       93 SELFPErwfHMVVVLHTSTEVLFERLTKRQYSEAKRAENMEAEIQCICEEEARDAYEDDIVLvrENDTLEQmaaTVEEIR 172
Cdd:COG1936  77 AHLVDV---DRVIVLRCNPEVLEERLEERGYSEEKIRENVEAEALDVILSEAVERFGEEKVY--EIDTTGR---TPEEVA 148


                ....
1Y63_A      173 ERVE 176
Cdd:COG1936 149 DEIL 152
AAA_18 pfam13238
AAA domain;
13-136 2.91e-26

AAA domain;


Pssm-ID: 433052 [Multi-domain]  Cd Length: 128  Bit Score: 97.11  E-value: 2.91e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1Y63_A         13 ILITGTPGTGKTSMAEmIAAELDGFqHLEVGKLVKENHFYTEYDTELD-THIIEEKDEDRLLDFMEPI--MVSRGNHVVD 89
Cdd:pfam13238   1 ILITGTPGVGKTTLAK-ELSKRLGF-GDNVRDLALENGLVLGDDPETReSKRLDEDKLDRLLDLLEENaaLEEGGNLIID 78

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
1Y63_A         90 YHSSELFPERWF-HMVVVLHTSTEVLFERLTKRQYSEAKRAENMEAEI 136
Cdd:pfam13238  79 GHLAELEPERAKdLVGIVLRASPEELLERLEKRGYEEAKIKENEEAEI 126
PRK03839 PRK03839
putative kinase; Provisional
 13-176 2.87e-16

putative kinase; Provisional


Pssm-ID: 179660  Cd Length: 180  Bit Score: 72.45  E-value: 2.87e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1Y63_A        13 ILITGTPGTGKTSMAEMIAAELdGFQHLEVGKLVKENHFYTEYDTELDThiieekDEDRLLDFMEPIMVSRgNHVVDYHS 92
Cdd:PRK03839   3 IAITGTPGVGKTTVSKLLAEKL-GYEYVDLTEFALKKGIGEEKDDEMEI------DFDKLAYFIEEEFKEK-NVVLDGHL 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1Y63_A        93 SELFPErwfHMVVVLHTSTEVLFERLTKRQYSEAKRAENMEAEIQCICEEEARDAYEDDIVLVRENDTLEQMaatVEEIR 172
Cdd:PRK03839  75 SHLLPV---DYVIVLRAHPKIIKERLKERGYSKKKILENVEAELVDVCLCEALEEKEKVIEVDTTGKTPEEV---VEEIL 148


                 ....
1Y63_A       173 ERVE 176
Cdd:PRK03839 149 ELIK 152
AAA cd00009
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ...
 5-88 6.29e-05

The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.


Pssm-ID: 99707 [Multi-domain]  Cd Length: 151  Bit Score: 41.36  E-value: 6.29e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1Y63_A        5 MEQPKGINILITGTPGTGKTSMAEMIAAELdgfqhlevgKLVKENHFYTEYDTELDTHIIEEKDEDRLLDFMEPIMVSRG 84
Cdd:cd00009  14 LELPPPKNLLLYGPPGTGKTTLARAIANEL---------FRPGAPFLYLNASDLLEGLVVAELFGHFLVRLLFELAEKAK 84


                ....
1Y63_A       85 NHVV 88
Cdd:cd00009  85 PGVL 88
cyt_kin_arch TIGR02173
cytidylate kinase, putative; Proteins in this family are believed to be cytidylate kinase. ...
 13-122 9.44e-05

cytidylate kinase, putative; Proteins in this family are believed to be cytidylate kinase. Members of this family are found in the archaea and in spirochaetes, and differ considerably from the common bacterial form of cytidylate kinase described by TIGR00017.


Pssm-ID: 274012 [Multi-domain]  Cd Length: 171  Bit Score: 40.87  E-value: 9.44e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1Y63_A         13 ILITGTPGTGKTSMAEMIAAELdGFQHLEVGKL-----------VKENHFYTEYDTELDthiieeKDEDRLLdfmEPIMV 81
Cdd:TIGR02173   3 ITISGPPGSGKTTVAKILAEKL-SLKLISAGDIfrelaakmgldLIEFLNYAEENPEID------KKIDRRI---HEIAL 72

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
1Y63_A         82 SRGNHVVDYHSSELFPERWFHMVVVLHTSTEVLFERLTKRQ 122
Cdd:TIGR02173  73 KEKNVVLESRLAGWIVREYADVKIWLKAPLEVRARRIAKRE 113
AAA pfam00004
ATPase family associated with various cellular activities (AAA); AAA family proteins often ...
 13-35 1.13e-04

ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.


Pssm-ID: 459627 [Multi-domain]  Cd Length: 130  Bit Score: 40.27  E-value: 1.13e-04
                          10        20
                  ....*....|....*....|...
1Y63_A         13 ILITGTPGTGKTSMAEMIAAELD 35
Cdd:pfam00004   1 LLLYGPPGTGKTTLAKAVAKELG 23
PRK06835 PRK06835
DNA replication protein DnaC; Validated
 12-68 1.99e-04

DNA replication protein DnaC; Validated


Pssm-ID: 235871 [Multi-domain]  Cd Length: 329  Bit Score: 40.65  E-value: 1.99e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
1Y63_A        12 NILITGTPGTGKTSMAEMIAAELdgfqhLEVGKLV------------KENHFYTEYDTELDTHIIEEKD 68
Cdd:PRK06835 185 NLLFYGNTGTGKTFLSNCIAKEL-----LDRGKSViyrtadelieilREIRFNNDKELEEVYDLLINCD 248
RecA-like_protease cd19481
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of ...
 5-35 2.09e-04

proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410889 [Multi-domain]  Cd Length: 158  Bit Score: 39.96  E-value: 2.09e-04
                        10        20        30
                ....*....|....*....|....*....|.
1Y63_A        5 MEQPKGINILITGTPGTGKTSMAEMIAAELD 35
Cdd:cd19481  21 YGLGLPKGILLYGPPGTGKTLLAKALAGELG 51
RecA-like_CDC48_NLV2_r1-like cd19503
first of two ATPase domains of CDC48 and NLV2, and similar ATPase domains; CDC48 in yeast and ...
 8-35 5.73e-04

first of two ATPase domains of CDC48 and NLV2, and similar ATPase domains; CDC48 in yeast and p97 or VCP metazoans is an ATP-dependent molecular chaperone which plays an essential role in many cellular processes, by segregating polyubiquitinated proteins from complexes or membranes. Cdc48/p97 consists of an N-terminal domain and two ATPase domains; this subfamily represents the first of the two ATPase domains. This subfamily also includes the first of the two ATPase domains of NVL (nuclear VCP-like protein) 2, an isoform of NVL mainly present in the nucleolus, which is involved in ribosome biogenesis, in telomerase assembly and the regulation of telomerase activity, and in pre-rRNA processing. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410911 [Multi-domain]  Cd Length: 165  Bit Score: 38.81  E-value: 5.73e-04
                        10        20
                ....*....|....*....|....*...
1Y63_A        8 PKGIniLITGTPGTGKTSMAEMIAAELD 35
Cdd:cd19503  34 PRGV--LLHGPPGTGKTLLARAVANEAG 59
AAA_17 pfam13207
AAA domain;
16-122 6.02e-04

AAA domain;


Pssm-ID: 463810 [Multi-domain]  Cd Length: 136  Bit Score: 38.37  E-value: 6.02e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1Y63_A         16 TGTPGTGKTSMAEMIAAELdGFQHLEVGKLVKENHFYTEYDTELDTHIIEEKDEDRLLD--FMEPIMVSRGNH--VVDYH 91
Cdd:pfam13207   1 TGVPGSGKTTQLKKLAEKL-GFPHISAGDLLREEAKERGLVEDRDEMRKLPLEPQKELQklAAERIAEEAGEGgvIVDGH 79

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
1Y63_A         92 SS--------ELFPERWFH-----MVVVLHTSTEVLFERLTKRQ 122
Cdd:pfam13207  80 PRiktpagylPGLPVEVLRelkpdAIILLEADPEEILERRLKDR 123
SpoVK COG0464
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle ...
 8-46 6.22e-04

AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];


Pssm-ID: 440232 [Multi-domain]  Cd Length: 397  Bit Score: 39.51  E-value: 6.22e-04
                        10        20        30        40
                ....*....|....*....|....*....|....*....|
1Y63_A        8 PKGINILITGTPGTGKTSMAEMIAAELDG-FQHLEVGKLV 46
Cdd:COG0464 189 PPPRGLLLYGPPGTGKTLLARALAGELGLpLIEVDLSDLV 228
PspF COG1221
Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain ...
 8-30 6.32e-04

Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain [Transcription, Signal transduction mechanisms];


Pssm-ID: 440834 [Multi-domain]  Cd Length: 835  Bit Score: 39.71  E-value: 6.32e-04
                        10        20
                ....*....|....*....|...
1Y63_A        8 PKGINILITGTPGTGKTSMAEMI 30
Cdd:COG1221 128 PKGLHTLILGPTGVGKSFFAELM 150
COG1223 COG1223
Predicted ATPase, AAA+ superfamily [General function prediction only];
12-35 7.88e-04

Predicted ATPase, AAA+ superfamily [General function prediction only];


Pssm-ID: 440836 [Multi-domain]  Cd Length: 246  Bit Score: 38.71  E-value: 7.88e-04
                        10        20
                ....*....|....*....|....
1Y63_A       12 NILITGTPGTGKTSMAEMIAAELD 35
Cdd:COG1223  37 KILFYGPPGTGKTMLAEALAGELK 60
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 9-35 8.21e-04

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 38.12  E-value: 8.21e-04
                           10        20
                   ....*....|....*....|....*..
1Y63_A           9 KGINILITGTPGTGKTSMAEMIAAELD 35
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELG 27
AAA_22 pfam13401
AAA domain;
5-88 9.04e-04

AAA domain;


Pssm-ID: 379165 [Multi-domain]  Cd Length: 129  Bit Score: 37.71  E-value: 9.04e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1Y63_A          5 MEQPKGInILITGTPGTGKTSMAEMIAAELDGFQ----HLEVGKLVKENHFYTEYDTELDTHIIEEKDEDRLLDFMEPIM 80
Cdd:pfam13401   1 IRFGAGI-LVLTGESGTGKTTLLRRLLEQLPEVRdsvvFVDLPSGTSPKDLLRALLRALGLPLSGRLSKEELLAALQQLL 79


                  ....*...
1Y63_A         81 VSRGNHVV 88
Cdd:pfam13401  80 LALAVAVV 87
AAA_33 pfam13671
AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the ...
 13-137 1.01e-03

AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the AAA superfamily. Many of the proteins in this family are just short fragments so there is no Walker B motif.


Pssm-ID: 463952 [Multi-domain]  Cd Length: 143  Bit Score: 37.67  E-value: 1.01e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1Y63_A         13 ILITGTPGTGKTSMAEMIAAELdGFQHLEVGKLVKeNHFYTEYDTELDTHIIEEKDEDRLLDFMEpIMVSRGNHVV-Dyh 91
Cdd:pfam13671   2 ILLVGLPGSGKSTLARRLLEEL-GAVRLSSDDERK-RLFGEGRPSISYYTDATDRTYERLHELAR-IALRAGRPVIlD-- 76

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
1Y63_A         92 SSELFPE---RWFHM---------VVVLHTSTEVLFERLTKRQYSEAKRAENMEAEIQ 137
Cdd:pfam13671  77 ATNLRRDeraRLLALareygvpvrIVVFEAPEEVLRERLAARARAGGDPSDVPEEVLD 134
RPT1 COG1222
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein ...
 6-35 1.79e-03

ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440835 [Multi-domain]  Cd Length: 326  Bit Score: 38.06  E-value: 1.79e-03
                        10        20        30
                ....*....|....*....|....*....|
1Y63_A        6 EQPKGIniLITGTPGTGKTSMAEMIAAELD 35
Cdd:COG1222 110 EPPKGV--LLYGPPGTGKTLLAKAVAGELG 137
GntK cd02021
Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting ...
 13-122 1.96e-03

Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits.


Pssm-ID: 238979 [Multi-domain]  Cd Length: 150  Bit Score: 36.85  E-value: 1.96e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1Y63_A       13 ILITGTPGTGKTSMAEMIAAEL-------DGFQHLEVGKLVKENHfyteydtELDthiieekDEDR------LLDFMEPI 79
Cdd:cd02021   2 IVVMGVSGSGKSTVGKALAERLgapfidgDDLHPPANIAKMAAGI-------PLN-------DEDRwpwlqaLTDALLAK 67

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|...
1Y63_A       80 MVSRGNHVVDYHSS----------ELFPERWFHmVVVLHTSTEVLFERLTKRQ 122
Cdd:cd02021  68 LASAGEGVVVACSAlkriyrdilrGGAANPRVR-FVHLDGPREVLAERLAARK 119
PRK01184 PRK01184
flagellar hook-basal body complex protein FliE;
13-176 2.71e-03

flagellar hook-basal body complex protein FliE;


Pssm-ID: 234914 [Multi-domain]  Cd Length: 184  Bit Score: 36.85  E-value: 2.71e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1Y63_A        13 ILITGTPGTGKtSMAEMIAAELdGFQHLEVGKLVKEnhfyteydtELDTHIIEEKDE----------------------- 69
Cdd:PRK01184   4 IGVVGMPGSGK-GEFSKIAREM-GIPVVVMGDVIRE---------EVKKRGLEPTDEnigkvaidlrkelgmdavakrtv 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1Y63_A        70 DRLLDFMEPIMV---SRGNHVVDYHSSElFPERwFHmVVVLHTSTEVLFERLTKRQYSEakraenmeaEIQCICEEEARD 146
Cdd:PRK01184  73 PKIREKGDEVVVidgVRGDAEVEYFRKE-FPED-FI-LIAIHAPPEVRFERLKKRGRSD---------DPKSWEELEERD 140

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
1Y63_A       147 AYE-----------DDIVLVrENDTLEQMAATVEEIRERVE 176
Cdd:PRK01184 141 ERElswgigevialADYMIV-NDSTLEEFRARVRKLLERIL 180
RAD55 COG0467
RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms];
8-33 3.35e-03

RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms];


Pssm-ID: 440235 [Multi-domain]  Cd Length: 221  Bit Score: 36.82  E-value: 3.35e-03
                        10        20
                ....*....|....*....|....*.
1Y63_A        8 PKGINILITGTPGTGKTSMAEMIAAE 33
Cdd:COG0467  18 PRGSSTLLSGPPGTGKTTLALQFLAE 43
ruvB PRK00080
Holliday junction branch migration DNA helicase RuvB;
13-34 6.70e-03

Holliday junction branch migration DNA helicase RuvB;


Pssm-ID: 234619 [Multi-domain]  Cd Length: 328  Bit Score: 36.26  E-value: 6.70e-03
                         10        20
                 ....*....|....*....|..
1Y63_A        13 ILITGTPGTGKTSMAEMIAAEL 34
Cdd:PRK00080  54 VLLYGPPGLGKTTLANIIANEM 75
ftsH CHL00176
cell division protein; Validated
 8-33 8.20e-03

cell division protein; Validated


Pssm-ID: 214386 [Multi-domain]  Cd Length: 638  Bit Score: 36.18  E-value: 8.20e-03
                         10        20
                 ....*....|....*....|....*.
1Y63_A         8 PKGIniLITGTPGTGKTSMAEMIAAE 33
Cdd:CHL00176 216 PKGV--LLVGPPGTGKTLLAKAIAGE 239
AAA_2 pfam07724
AAA domain (Cdc48 subfamily); This Pfam entry includes some of the AAA proteins not detected ...
 11-38 8.50e-03

AAA domain (Cdc48 subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.


Pssm-ID: 400187 [Multi-domain]  Cd Length: 168  Bit Score: 35.25  E-value: 8.50e-03
                          10        20
                  ....*....|....*....|....*...
1Y63_A         11 INILITGTPGTGKTSMAEMIAAELDGFQ 38
Cdd:pfam07724   4 GSFLFLGPTGVGKTELAKALAELLFGDE 31
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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