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Conserved domains on  [gi|159163699|pdb|1ZW8|A]
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Chain A, Zinc-responsive transcriptional regulator ZAP1

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Zap1_zf2 super family cl39573
Zap1 zinc finger 2; This domain can be found in Zap1 present in Saccharomyces cerevisiae. Zap1 ...
 41-64 9.85e-07

Zap1 zinc finger 2; This domain can be found in Zap1 present in Saccharomyces cerevisiae. Zap1 regulates S. cerevisiae which mediates the transcription of genes encoding uptake vacuolar transporters. This domain corresponds to zinc finger 2 (zf2) which has been shown to be a constitutive transcriptional activator. The two zinc fingers interactions stabilizes Zn(II)-binding.


The actual alignment was detected with superfamily member pfam18217:

Pssm-ID: 436352  Cd Length: 24  Bit Score: 40.31  E-value: 9.85e-07
                         10        20
                 ....*....|....*....|....
1ZW8_A        41 CNWEDCDFLGDDTASIVNHINAQH 64
Cdd:pfam18217  1 CNWKDCDFEGEDICSLINHINDKH 24
COG5048 super family cl34881
FOG: Zn-finger [General function prediction only];
1-61 7.02e-03

FOG: Zn-finger [General function prediction only];


The actual alignment was detected with superfamily member COG5048:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 32.75  E-value: 7.02e-03
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|.
1ZW8_A        1 DLKCKWKECPESASSLFDLQRHLLKDHVSQdfkHPMEPLACNWEDCDFLGDDTASIVNHIN 61
Cdd:COG5048 287 SLPIKSKQCNISFSRSSPLTRHLRSVNHSG---ESLKPFSCPYSLCGKLFSRNDALKRHIL 344
 
Name Accession Description Interval E-value
Zap1_zf2 pfam18217
Zap1 zinc finger 2; This domain can be found in Zap1 present in Saccharomyces cerevisiae. Zap1 ...
 41-64 9.85e-07

Zap1 zinc finger 2; This domain can be found in Zap1 present in Saccharomyces cerevisiae. Zap1 regulates S. cerevisiae which mediates the transcription of genes encoding uptake vacuolar transporters. This domain corresponds to zinc finger 2 (zf2) which has been shown to be a constitutive transcriptional activator. The two zinc fingers interactions stabilizes Zn(II)-binding.


Pssm-ID: 436352  Cd Length: 24  Bit Score: 40.31  E-value: 9.85e-07
                         10        20
                 ....*....|....*....|....
1ZW8_A        41 CNWEDCDFLGDDTASIVNHINAQH 64
Cdd:pfam18217  1 CNWKDCDFEGEDICSLINHINDKH 24
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
1-61 7.02e-03

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 32.75  E-value: 7.02e-03
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|.
1ZW8_A        1 DLKCKWKECPESASSLFDLQRHLLKDHVSQdfkHPMEPLACNWEDCDFLGDDTASIVNHIN 61
Cdd:COG5048 287 SLPIKSKQCNISFSRSSPLTRHLRSVNHSG---ESLKPFSCPYSLCGKLFSRNDALKRHIL 344
 
Name Accession Description Interval E-value
Zap1_zf2 pfam18217
Zap1 zinc finger 2; This domain can be found in Zap1 present in Saccharomyces cerevisiae. Zap1 ...
 41-64 9.85e-07

Zap1 zinc finger 2; This domain can be found in Zap1 present in Saccharomyces cerevisiae. Zap1 regulates S. cerevisiae which mediates the transcription of genes encoding uptake vacuolar transporters. This domain corresponds to zinc finger 2 (zf2) which has been shown to be a constitutive transcriptional activator. The two zinc fingers interactions stabilizes Zn(II)-binding.


Pssm-ID: 436352  Cd Length: 24  Bit Score: 40.31  E-value: 9.85e-07
                         10        20
                 ....*....|....*....|....
1ZW8_A        41 CNWEDCDFLGDDTASIVNHINAQH 64
Cdd:pfam18217  1 CNWKDCDFEGEDICSLINHINDKH 24
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
1-61 7.02e-03

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 32.75  E-value: 7.02e-03
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|.
1ZW8_A        1 DLKCKWKECPESASSLFDLQRHLLKDHVSQdfkHPMEPLACNWEDCDFLGDDTASIVNHIN 61
Cdd:COG5048 287 SLPIKSKQCNISFSRSSPLTRHLRSVNHSG---ESLKPFSCPYSLCGKLFSRNDALKRHIL 344
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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