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Conserved domains on  [gi|88192895|pdb|2F9H|A]
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Chain A, PTS system, IIA component

Protein Classification

PTS glucitol/sorbitol transporter subunit IIA( domain architecture ID 10510876)

PTS glucitol/sorbitol transporter subunit IIA is a component of the glucitol/sorbitol-specific phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active transport system that catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PTSIIA_gutA pfam03829
PTS system glucitol/sorbitol-specific IIA component;
9-122 9.94e-39

PTS system glucitol/sorbitol-specific IIA component;


:

Pssm-ID: 427533  Cd Length: 113  Bit Score: 126.05  E-value: 9.94e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2F9H_A          9 QATVTEIGKHAIDD-SEK*IILFGETATDTLKQHAVIQSFPEkDQVTLAEGDHLKIGDTNYTITKVGSFANSNLQSIAHS 87
Cdd:pfam03829   3 QTTVTEIGPEAEDFlEEKMLILFGENAPDELADYCVIHDVGE-LKGEIKPGDTLKIGGQEYKITAVGEVANQNLRELGHI 81

                          90       100       110
                  ....*....|....*....|....*....|....*
2F9H_A         88 TLIFADAPTDEddvIRNGVYLTPHQLPKITIGTTI 122
Cdd:pfam03829  82 TLKFDGAPEAE---LPGTIYLEGKELPEIKVGSTI 113
 
Name Accession Description Interval E-value
PTSIIA_gutA pfam03829
PTS system glucitol/sorbitol-specific IIA component;
9-122 9.94e-39

PTS system glucitol/sorbitol-specific IIA component;


Pssm-ID: 427533  Cd Length: 113  Bit Score: 126.05  E-value: 9.94e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2F9H_A          9 QATVTEIGKHAIDD-SEK*IILFGETATDTLKQHAVIQSFPEkDQVTLAEGDHLKIGDTNYTITKVGSFANSNLQSIAHS 87
Cdd:pfam03829   3 QTTVTEIGPEAEDFlEEKMLILFGENAPDELADYCVIHDVGE-LKGEIKPGDTLKIGGQEYKITAVGEVANQNLRELGHI 81

                          90       100       110
                  ....*....|....*....|....*....|....*
2F9H_A         88 TLIFADAPTDEddvIRNGVYLTPHQLPKITIGTTI 122
Cdd:pfam03829  82 TLKFDGAPEAE---LPGTIYLEGKELPEIKVGSTI 113
SrlB COG3731
Phosphotransferase system sorbitol-specific IIA component [Carbohydrate transport and ...
 6-125 1.08e-35

Phosphotransferase system sorbitol-specific IIA component [Carbohydrate transport and metabolism];


Pssm-ID: 442945  Cd Length: 117  Bit Score: 118.72  E-value: 1.08e-35
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2F9H_A        6 WK*QATVTEIGKHAID-DSEK*IILFGETATDTLKQHAVIQSFpEKDQVTLAEGDHLKIGDTNYTITKVGSFANSNLQSI 84
Cdd:COG3731   1 MIYQTTITEIGEEAADfLEEGMLILFGENAPDDLADYCVIHEV-GELKGEIKVGDVLKIGGQEYTITAVGDVANKNLREL 79

                        90       100       110       120
                ....*....|....*....|....*....|....*....|.
2F9H_A       85 AHSTLIFADAPTDEddvIRNGVYLTPHQLPKITIGTTIDYL 125
Cdd:COG3731  80 GHITLKFDGATEAE---LPGTIHLEGKELPAIKVGTTITIE 117
PRK10377 PRK10377
PTS glucitol/sorbitol transporter subunit IIA;
9-98 2.88e-08

PTS glucitol/sorbitol transporter subunit IIA;


Pssm-ID: 182419  Cd Length: 120  Bit Score: 48.57  E-value: 2.88e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2F9H_A         9 QATVTEIGKHAIDD-SEK*IILFGETATDTLKQHAVIQSFPEKDQvTLAEGDHLKIGDTNYTITKVGSFANSNLQSIAHS 87
Cdd:PRK10377   6 QTTITRIGASATDAlSDQMLITFREGAPADIEEYCFIHCHGELKG-ALQPGLQFELGQHRYPVTAVGSVAEDNLRELGHV 84

                         90
                 ....*....|.
2F9H_A        88 TLIFADAPTDE 98
Cdd:PRK10377  85 TLRFDGLNEAE 95
 
Name Accession Description Interval E-value
PTSIIA_gutA pfam03829
PTS system glucitol/sorbitol-specific IIA component;
9-122 9.94e-39

PTS system glucitol/sorbitol-specific IIA component;


Pssm-ID: 427533  Cd Length: 113  Bit Score: 126.05  E-value: 9.94e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2F9H_A          9 QATVTEIGKHAIDD-SEK*IILFGETATDTLKQHAVIQSFPEkDQVTLAEGDHLKIGDTNYTITKVGSFANSNLQSIAHS 87
Cdd:pfam03829   3 QTTVTEIGPEAEDFlEEKMLILFGENAPDELADYCVIHDVGE-LKGEIKPGDTLKIGGQEYKITAVGEVANQNLRELGHI 81

                          90       100       110
                  ....*....|....*....|....*....|....*
2F9H_A         88 TLIFADAPTDEddvIRNGVYLTPHQLPKITIGTTI 122
Cdd:pfam03829  82 TLKFDGAPEAE---LPGTIYLEGKELPEIKVGSTI 113
SrlB COG3731
Phosphotransferase system sorbitol-specific IIA component [Carbohydrate transport and ...
 6-125 1.08e-35

Phosphotransferase system sorbitol-specific IIA component [Carbohydrate transport and metabolism];


Pssm-ID: 442945  Cd Length: 117  Bit Score: 118.72  E-value: 1.08e-35
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2F9H_A        6 WK*QATVTEIGKHAID-DSEK*IILFGETATDTLKQHAVIQSFpEKDQVTLAEGDHLKIGDTNYTITKVGSFANSNLQSI 84
Cdd:COG3731   1 MIYQTTITEIGEEAADfLEEGMLILFGENAPDDLADYCVIHEV-GELKGEIKVGDVLKIGGQEYTITAVGDVANKNLREL 79

                        90       100       110       120
                ....*....|....*....|....*....|....*....|.
2F9H_A       85 AHSTLIFADAPTDEddvIRNGVYLTPHQLPKITIGTTIDYL 125
Cdd:COG3731  80 GHITLKFDGATEAE---LPGTIHLEGKELPAIKVGTTITIE 117
PRK10377 PRK10377
PTS glucitol/sorbitol transporter subunit IIA;
9-98 2.88e-08

PTS glucitol/sorbitol transporter subunit IIA;


Pssm-ID: 182419  Cd Length: 120  Bit Score: 48.57  E-value: 2.88e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2F9H_A         9 QATVTEIGKHAIDD-SEK*IILFGETATDTLKQHAVIQSFPEKDQvTLAEGDHLKIGDTNYTITKVGSFANSNLQSIAHS 87
Cdd:PRK10377   6 QTTITRIGASATDAlSDQMLITFREGAPADIEEYCFIHCHGELKG-ALQPGLQFELGQHRYPVTAVGSVAEDNLRELGHV 84

                         90
                 ....*....|.
2F9H_A        88 TLIFADAPTDE 98
Cdd:PRK10377  85 TLRFDGLNEAE 95
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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