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Conserved domains on  [gi|203282572|pdb|3EEY|A]
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Chain A, Putative rRNA methylase

Protein Classification

class I SAM-dependent methyltransferase( domain architecture ID 13392866)

class I SAM-dependent methyltransferase catalyzes the methylation of one or more specific substrates using S-adenosyl-L-methionine (SAM or AdoMet) as the methyl donor

CATH:  3.40.50.150
EC:  2.1.1.-
Gene Ontology:  GO:1904047|GO:0008168|GO:0032259|GO:0008757
PubMed:  12504684|12826405
SCOP:  3000118

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
rRNA_methylase pfam06962
Putative rRNA methylase; This family contains a number of putative rRNA methylases. Note that ...
 50-186 4.19e-83

Putative rRNA methylase; This family contains a number of putative rRNA methylases. Note that many family members are hypothetical proteins.


:

Pssm-ID: 429214  Cd Length: 137  Bit Score: 242.31  E-value: 4.19e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3EEY_A         50 VFGFDIQDKAIANTTKKLTDLNLIDRVTLIKDGHQNMDKYIDCPVKAVMFNLGYLPSGDHSISTRPETTIQALSKAMELL 129
Cdd:pfam06962   1 VYAFDIQEEALENTRERLEEEGLEERVELILDGHENLDEYVPGPVDAAMFNLGYLPGGDKSITTKPETTLKALEAALELL 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
3EEY_A        130 VTGGIITVVIYYGGDTGFEEKEKVLEFLKGVDQKKFIVQRTDFINQANCPPILVCIE 186
Cdd:pfam06962  81 KPGGIISLVVYPGHPGGKEEKEAVLEYLSSLDQKKYNVLKYEFLNQPNNPPFLVLIE 137
Gcd14 super family cl34476
tRNA A58 N-methylase Trm61 [Translation, ribosomal structure and biogenesis]; tRNA A58 ...
 15-80 3.95e-09

tRNA A58 N-methylase Trm61 [Translation, ribosomal structure and biogenesis]; tRNA A58 N-methylase Trm61 is part of the Pathway/BioSystem: tRNA modification


The actual alignment was detected with superfamily member COG2519:

Pssm-ID: 442009 [Multi-domain]  Cd Length: 249  Bit Score: 54.40  E-value: 3.95e-09
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*...
3EEY_A       15 YIKMF--VKEGDTVVDATCGNGNDTAFLASLVGENGRVFGFDIQDKAIANTTKKLTDLNLIDRVTLIK 80
Cdd:COG2519  82 YIIARldIFPGARVLEAGTGSGALTLALARAVGPEGKVYSYERREDFAEIARKNLERFGLPDNVELKL 149
 
Name Accession Description Interval E-value
rRNA_methylase pfam06962
Putative rRNA methylase; This family contains a number of putative rRNA methylases. Note that ...
 50-186 4.19e-83

Putative rRNA methylase; This family contains a number of putative rRNA methylases. Note that many family members are hypothetical proteins.


Pssm-ID: 429214  Cd Length: 137  Bit Score: 242.31  E-value: 4.19e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3EEY_A         50 VFGFDIQDKAIANTTKKLTDLNLIDRVTLIKDGHQNMDKYIDCPVKAVMFNLGYLPSGDHSISTRPETTIQALSKAMELL 129
Cdd:pfam06962   1 VYAFDIQEEALENTRERLEEEGLEERVELILDGHENLDEYVPGPVDAAMFNLGYLPGGDKSITTKPETTLKALEAALELL 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
3EEY_A        130 VTGGIITVVIYYGGDTGFEEKEKVLEFLKGVDQKKFIVQRTDFINQANCPPILVCIE 186
Cdd:pfam06962  81 KPGGIISLVVYPGHPGGKEEKEAVLEYLSSLDQKKYNVLKYEFLNQPNNPPFLVLIE 137
Gcd14 COG2519
tRNA A58 N-methylase Trm61 [Translation, ribosomal structure and biogenesis]; tRNA A58 ...
 15-80 3.95e-09

tRNA A58 N-methylase Trm61 [Translation, ribosomal structure and biogenesis]; tRNA A58 N-methylase Trm61 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 442009 [Multi-domain]  Cd Length: 249  Bit Score: 54.40  E-value: 3.95e-09
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*...
3EEY_A       15 YIKMF--VKEGDTVVDATCGNGNDTAFLASLVGENGRVFGFDIQDKAIANTTKKLTDLNLIDRVTLIK 80
Cdd:COG2519  82 YIIARldIFPGARVLEAGTGSGALTLALARAVGPEGKVYSYERREDFAEIARKNLERFGLPDNVELKL 149
RmsH COG0275
16S rRNA C1402 N4-methylase RsmH [Translation, ribosomal structure and biogenesis]; 16S rRNA ...
 20-102 1.05e-07

16S rRNA C1402 N4-methylase RsmH [Translation, ribosomal structure and biogenesis]; 16S rRNA C1402 N4-methylase RsmH is part of the Pathway/BioSystem: 16S rRNA modification


Pssm-ID: 440044  Cd Length: 312  Bit Score: 50.83  E-value: 1.05e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3EEY_A       20 VKEGDTVVDATCGNGNDT-AFLASLvGENGRVFGFDiQDK-AIANTTKKLTDLNliDRVTLIKDGHQNMDKYIDC----P 93
Cdd:COG0275  21 PKPGGVYVDGTLGGGGHSrAILERL-GPGGRLIGID-RDPdAIAAAKERLAEFG--DRFTLVHGNFSELDEVLAElgieK 96


                ....*....
3EEY_A       94 VKAVMFNLG 102
Cdd:COG0275  97 VDGILLDLG 105
PRK08317 PRK08317
hypothetical protein; Provisional
 11-61 2.75e-07

hypothetical protein; Provisional


Pssm-ID: 181382 [Multi-domain]  Cd Length: 241  Bit Score: 49.16  E-value: 2.75e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
3EEY_A        11 QSHDYIKMFVKEGDTVVDATCGNGNDTAFLASLVGENGRVFGFDIQDKAIA 61
Cdd:PRK08317   8 RARTFELLAVQPGDRVLDVGCGPGNDARELARRVGPEGRVVGIDRSEAMLA 58
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 25-142 2.26e-06

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 44.73  E-value: 2.26e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3EEY_A       25 TVVDATCGNGNDTAFLASLVGenGRVFGFDIqDKAIANTTKKLTDLNLIDRVTLIkdgHQNMDKYIDCPVK---AVMFnl 101
Cdd:cd02440   1 RVLDLGCGTGALALALASGPG--ARVTGVDI-SPVALELARKAAAALLADNVEVL---KGDAEELPPEADEsfdVIIS-- 72

                        90       100       110       120
                ....*....|....*....|....*....|....*....|.
3EEY_A      102 gylpsgDHSISTRPETTIQALSKAMELLVTGGIITVVIYYG 142
Cdd:cd02440  73 ------DPPLHHLVEDLARFLEEARRLLKPGGVLVLTLVLA 107
 
Name Accession Description Interval E-value
rRNA_methylase pfam06962
Putative rRNA methylase; This family contains a number of putative rRNA methylases. Note that ...
 50-186 4.19e-83

Putative rRNA methylase; This family contains a number of putative rRNA methylases. Note that many family members are hypothetical proteins.


Pssm-ID: 429214  Cd Length: 137  Bit Score: 242.31  E-value: 4.19e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3EEY_A         50 VFGFDIQDKAIANTTKKLTDLNLIDRVTLIKDGHQNMDKYIDCPVKAVMFNLGYLPSGDHSISTRPETTIQALSKAMELL 129
Cdd:pfam06962   1 VYAFDIQEEALENTRERLEEEGLEERVELILDGHENLDEYVPGPVDAAMFNLGYLPGGDKSITTKPETTLKALEAALELL 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
3EEY_A        130 VTGGIITVVIYYGGDTGFEEKEKVLEFLKGVDQKKFIVQRTDFINQANCPPILVCIE 186
Cdd:pfam06962  81 KPGGIISLVVYPGHPGGKEEKEAVLEYLSSLDQKKYNVLKYEFLNQPNNPPFLVLIE 137
Gcd14 COG2519
tRNA A58 N-methylase Trm61 [Translation, ribosomal structure and biogenesis]; tRNA A58 ...
 15-80 3.95e-09

tRNA A58 N-methylase Trm61 [Translation, ribosomal structure and biogenesis]; tRNA A58 N-methylase Trm61 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 442009 [Multi-domain]  Cd Length: 249  Bit Score: 54.40  E-value: 3.95e-09
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*...
3EEY_A       15 YIKMF--VKEGDTVVDATCGNGNDTAFLASLVGENGRVFGFDIQDKAIANTTKKLTDLNLIDRVTLIK 80
Cdd:COG2519  82 YIIARldIFPGARVLEAGTGSGALTLALARAVGPEGKVYSYERREDFAEIARKNLERFGLPDNVELKL 149
RmsH COG0275
16S rRNA C1402 N4-methylase RsmH [Translation, ribosomal structure and biogenesis]; 16S rRNA ...
 20-102 1.05e-07

16S rRNA C1402 N4-methylase RsmH [Translation, ribosomal structure and biogenesis]; 16S rRNA C1402 N4-methylase RsmH is part of the Pathway/BioSystem: 16S rRNA modification


Pssm-ID: 440044  Cd Length: 312  Bit Score: 50.83  E-value: 1.05e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3EEY_A       20 VKEGDTVVDATCGNGNDT-AFLASLvGENGRVFGFDiQDK-AIANTTKKLTDLNliDRVTLIKDGHQNMDKYIDC----P 93
Cdd:COG0275  21 PKPGGVYVDGTLGGGGHSrAILERL-GPGGRLIGID-RDPdAIAAAKERLAEFG--DRFTLVHGNFSELDEVLAElgieK 96


                ....*....
3EEY_A       94 VKAVMFNLG 102
Cdd:COG0275  97 VDGILLDLG 105
SmtA COG0500
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, ...
 21-140 1.78e-07

SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only];


Pssm-ID: 440266 [Multi-domain]  Cd Length: 199  Bit Score: 49.14  E-value: 1.78e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3EEY_A       21 KEGDTVVDATCGNGNDTAFLASLVGenGRVFGFDIQDKAIANTTKKLTDLNLiDRVTLIkdgHQNMDKYIDCPVKA--VM 98
Cdd:COG0500  25 PKGGRVLDLGCGTGRNLLALAARFG--GRVIGIDLSPEAIALARARAAKAGL-GNVEFL---VADLAELDPLPAESfdLV 98

                        90       100       110       120
                ....*....|....*....|....*....|....*....|..
3EEY_A       99 FNLGYLpsgdHSIStrPETTIQALSKAMELLVTGGIITVVIY 140
Cdd:COG0500  99 VAFGVL----HHLP--PEEREALLRELARALKPGGVLLLSAS 134
PRK08317 PRK08317
hypothetical protein; Provisional
 11-61 2.75e-07

hypothetical protein; Provisional


Pssm-ID: 181382 [Multi-domain]  Cd Length: 241  Bit Score: 49.16  E-value: 2.75e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
3EEY_A        11 QSHDYIKMFVKEGDTVVDATCGNGNDTAFLASLVGENGRVFGFDIQDKAIA 61
Cdd:PRK08317   8 RARTFELLAVQPGDRVLDVGCGPGNDARELARRVGPEGRVVGIDRSEAMLA 58
Methyltransf_31 pfam13847
Methyltransferase domain; This family appears to have methyltransferase activity.
 21-80 7.18e-07

Methyltransferase domain; This family appears to have methyltransferase activity.


Pssm-ID: 463998 [Multi-domain]  Cd Length: 150  Bit Score: 47.03  E-value: 7.18e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
3EEY_A         21 KEGDTVVDATCGNGNDTAFLASLVGENGRVFGFDIQDKAIANtTKKLTDLNLIDRVTLIK 80
Cdd:pfam13847   2 DKGMRVLDLGCGTGHLSFELAEELGPNAEVVGIDISEEAIEK-ARENAQKLGFDNVEFEQ 60
cbiT PRK00377
cobalt-precorrin-6Y C(15)-methyltransferase; Provisional
 17-80 9.27e-07

cobalt-precorrin-6Y C(15)-methyltransferase; Provisional


Pssm-ID: 234740  Cd Length: 198  Bit Score: 47.10  E-value: 9.27e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
3EEY_A        17 KMFVKEGDTVVDATCGNGNDTAFLASLVGENGRVFGFDIQDKAIANTTKKLTDLNLIDRVTLIK 80
Cdd:PRK00377  35 KLRLRKGDMILDIGCGTGSVTVEASLLVGETGKVYAVDKDEKAINLTRRNAEKFGVLNNIVLIK 98
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 25-142 2.26e-06

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 44.73  E-value: 2.26e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3EEY_A       25 TVVDATCGNGNDTAFLASLVGenGRVFGFDIqDKAIANTTKKLTDLNLIDRVTLIkdgHQNMDKYIDCPVK---AVMFnl 101
Cdd:cd02440   1 RVLDLGCGTGALALALASGPG--ARVTGVDI-SPVALELARKAAAALLADNVEVL---KGDAEELPPEADEsfdVIIS-- 72

                        90       100       110       120
                ....*....|....*....|....*....|....*....|.
3EEY_A      102 gylpsgDHSISTRPETTIQALSKAMELLVTGGIITVVIYYG 142
Cdd:cd02440  73 ------DPPLHHLVEDLARFLEEARRLLKPGGVLVLTLVLA 107
arsM PRK11873
arsenite methyltransferase;
21-65 9.86e-06

arsenite methyltransferase;


Pssm-ID: 237007 [Multi-domain]  Cd Length: 272  Bit Score: 44.94  E-value: 9.86e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
3EEY_A        21 KEGDTVVDATCGNGNDtAFLAS-LVGENGRVFGFDIQD----KAIANTTK 65
Cdd:PRK11873  76 KPGETVLDLGSGGGFD-CFLAArRVGPTGKVIGVDMTPemlaKARANARK 124
UbiE COG2226
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ...
 20-79 1.14e-05

Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis


Pssm-ID: 441828 [Multi-domain]  Cd Length: 143  Bit Score: 43.44  E-value: 1.14e-05
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|
3EEY_A       20 VKEGDTVVDATCGNGNDTAFLASLvgeNGRVFGFDIQDKAIANTTKKLTDLNLidRVTLI 79
Cdd:COG2226  20 LRPGARVLDLGCGTGRLALALAER---GARVTGVDISPEMLELARERAAEAGL--NVEFV 74
Methyltransf_25 pfam13649
Methyltransferase domain; This family appears to be a methyltransferase domain.
 26-133 2.53e-05

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 463945 [Multi-domain]  Cd Length: 96  Bit Score: 41.40  E-value: 2.53e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3EEY_A         26 VVDATCGNGNDTAFLASLVGenGRVFGFDIQDKAIANTTKKLTDLNLidRVTLIKDGHQNM---DKYIDCpvkAVMFN-L 101
Cdd:pfam13649   1 VLDLGCGTGRLTLALARRGG--ARVTGVDLSPEMLERARERAAEAGL--NVEFVQGDAEDLpfpDGSFDL---VVSSGvL 73

                          90       100       110
                  ....*....|....*....|....*....|..
3EEY_A        102 GYLPSGDHSistrpettiQALSKAMELLVTGG 133
Cdd:pfam13649  74 HHLPDPDLE---------AALREIARVLKPGG 96
ubiE PRK00216
bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol ...
 17-79 4.53e-05

bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE;


Pssm-ID: 234689 [Multi-domain]  Cd Length: 239  Bit Score: 42.83  E-value: 4.53e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
3EEY_A        17 KMFVKEGDTVVDATCGNGNDTAFLASLVGENGRVFGFDIQDKAIANTTKKLTDLNLIDRVTLI 79
Cdd:PRK00216  46 WLGVRPGDKVLDLACGTGDLAIALAKAVGKTGEVVGLDFSEGMLAVGREKLRDLGLSGNVEFV 108
Methyltransf_5 pfam01795
MraW methylase family; Members of this family are probably SAM dependent methyltransferases ...
 20-102 5.44e-05

MraW methylase family; Members of this family are probably SAM dependent methyltransferases based on Swiss:P18595. This family appears to be related to pfam01596.


Pssm-ID: 396387  Cd Length: 309  Bit Score: 42.71  E-value: 5.44e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3EEY_A         20 VKEGDTVVDATCGNGNDTAFLASLVGENgRVFGFDIQDKAIANTTKKLTDlnLIDRVTLIKDGHQNMDKYID----CPVK 95
Cdd:pfam01795  18 PKPDGVYIDCTLGGGGHSEAILEQLPEL-RLIGIDRDPQAIARAKERLKP--FEDRVTLVHGNFRFFKEALAelgvTKVD 94


                  ....*..
3EEY_A         96 AVMFNLG 102
Cdd:pfam01795  95 GILLDLG 101
PLN02233 PLN02233
ubiquinone biosynthesis methyltransferase
 8-66 6.84e-05

ubiquinone biosynthesis methyltransferase


Pssm-ID: 177877 [Multi-domain]  Cd Length: 261  Bit Score: 42.19  E-value: 6.84e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
3EEY_A         8 SLGQSHDYIKMFV-----KEGDTVVDATCGNGnDTAFLAS-LVGENGRVFGFDIQDKAIANTTKK 66
Cdd:PLN02233  54 SLGQHRIWKRMAVswsgaKMGDRVLDLCCGSG-DLAFLLSeKVGSDGKVMGLDFSSEQLAVAASR 117
Cfa COG2230
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport ...
 17-79 1.32e-04

Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport and metabolism];


Pssm-ID: 441831 [Multi-domain]  Cd Length: 158  Bit Score: 40.68  E-value: 1.32e-04
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|...
3EEY_A       17 KMFVKEGDTVVDATCGNGNDTAFLASLVGenGRVFGFDIQDKAIANTTKKLTDLNLIDRVTLI 79
Cdd:COG2230  46 KLGLKPGMRVLDIGCGWGGLALYLARRYG--VRVTGVTLSPEQLEYARERAAEAGLADRVEVR 106
UbiG COG2227
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ...
 13-135 3.26e-04

2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 441829 [Multi-domain]  Cd Length: 126  Bit Score: 38.85  E-value: 3.26e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3EEY_A       13 HDYIKMFVKEGDTVVDATCGNGNDTAFLASLvgeNGRVFGFDIQDKAIANTTKKLTDLNlidrVTLIKDGHQNMDkYIDC 92
Cdd:COG2227  15 AALLARLLPAGGRVLDVGCGTGRLALALARR---GADVTGVDISPEALEIARERAAELN----VDFVQGDLEDLP-LEDG 86

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*
3EEY_A       93 PVKAVMFN--LGYLPSgdhsistrPETTIQALSkamELLVTGGII 135
Cdd:COG2227  87 SFDLVICSevLEHLPD--------PAALLRELA---RLLKPGGLL 120
PCMT pfam01135
Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT);
18-84 1.14e-03

Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT);


Pssm-ID: 395902 [Multi-domain]  Cd Length: 205  Bit Score: 38.50  E-value: 1.14e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
3EEY_A         18 MFVKEGDTVVDATCGNGNDTAFLASLVGENGRVFGFD----IQDKAIANtTKKLTDLNLIDRVTlikDGHQ 84
Cdd:pfam01135  69 LELKPGMRVLEIGSGSGYLTACFARMVGEVGRVVSIEhipeLVEIARRN-LEKLGLENVIVVVG---DGRQ 135
Tam COG4106
Trans-aconitate methyltransferase [Energy production and conversion];
22-73 5.43e-03

Trans-aconitate methyltransferase [Energy production and conversion];


Pssm-ID: 443282 [Multi-domain]  Cd Length: 100  Bit Score: 35.18  E-value: 5.43e-03
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|..
3EEY_A       22 EGDTVVDATCGNGNDTAFLASLVGeNGRVFGFDIQDKAIANTTKKLTDLNLI 73
Cdd:COG4106   1 PPRRVLDLGCGTGRLTALLAERFP-GARVTGVDLSPEMLARARARLPNVRFV 51
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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