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Conserved domains on  [gi|317455363|pdb|3OUF|A]
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Chain A, Potassium channel protein

Protein Classification

potassium channel family protein( domain architecture ID 10545436)

potassium channel family protein spans the cell membrane to form a conduction pathway or pore, through which selective ions such as potassium, sodium, and calcium, translocate across cell membranes

Gene Ontology:  GO:0005267|GO:0034220|GO:0005216|GO:0071805|GO:0016020
PubMed:  15816170|9525859|11836519|11178249|1772658
SCOP:  4000034
TCDB:  1.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Ion_trans_2 pfam07885
Ion channel; This family includes the two membrane helix type ion channels found in bacteria.
 12-82 1.57e-14

Ion channel; This family includes the two membrane helix type ion channels found in bacteria.


:

Pssm-ID: 462301 [Multi-domain]  Cd Length: 78  Bit Score: 62.67  E-value: 1.57e-14
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
3OUF_A        12 VLTILTLISGTIFYSTVEGLR--PIDALYFSVVTLTTVGYGDFSPQTDFGKIFTILYIFIGIGLVFGFIHKLA 82
Cdd:pfam07885  1 IVLLLVLIFGTVYYLLEEGWEwsFLDALYFSFVTLTTVGYGDIVPLTDAGRLFTIFYILIGIPLFAIFLAVLG 73
 
Name Accession Description Interval E-value
Ion_trans_2 pfam07885
Ion channel; This family includes the two membrane helix type ion channels found in bacteria.
 12-82 1.57e-14

Ion channel; This family includes the two membrane helix type ion channels found in bacteria.


Pssm-ID: 462301 [Multi-domain]  Cd Length: 78  Bit Score: 62.67  E-value: 1.57e-14
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
3OUF_A        12 VLTILTLISGTIFYSTVEGLR--PIDALYFSVVTLTTVGYGDFSPQTDFGKIFTILYIFIGIGLVFGFIHKLA 82
Cdd:pfam07885  1 IVLLLVLIFGTVYYLLEEGWEwsFLDALYFSFVTLTTVGYGDIVPLTDAGRLFTIFYILIGIPLFAIFLAVLG 73
PRK10537 PRK10537
voltage-gated potassium channel protein;
12-71 1.17e-08

voltage-gated potassium channel protein;


Pssm-ID: 236711 [Multi-domain]  Cd Length: 393  Bit Score: 50.41  E-value: 1.17e-08
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
3OUF_A        12 VLTILTLISGTIFYSTV--EGLRP-----IDALYFSVVTLTTVGYGDFSPQTDFGKIFTILYIFIGI 71
Cdd:PRK10537 141 VISITSLLFYSTFGALYlgDGFSPpieslSTAFYFSIVTMSTVGYGDIVPVSESARLFTISVIILGI 207
TrkA COG0569
Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain [Inorganic ion ...
 13-78 2.34e-04

Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain [Inorganic ion transport and metabolism, Signal transduction mechanisms];


Pssm-ID: 440335 [Multi-domain]  Cd Length: 296  Bit Score: 38.12  E-value: 2.34e-04
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
3OUF_A       13 LTILTLISGTIFYSTVEGLRPIDALYFSVVTLTTVGYGDFSPQTDFGKIFTILYIFIGIGLVFGFI 78
Cdd:COG0569   1 LLILLLLLVLLFAMGIEGLVLLDALYGLLITLTTVTTLGGGLLDPVTLVAAIFLIGVVIIPLGYTL 66
 
Name Accession Description Interval E-value
Ion_trans_2 pfam07885
Ion channel; This family includes the two membrane helix type ion channels found in bacteria.
 12-82 1.57e-14

Ion channel; This family includes the two membrane helix type ion channels found in bacteria.


Pssm-ID: 462301 [Multi-domain]  Cd Length: 78  Bit Score: 62.67  E-value: 1.57e-14
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
3OUF_A        12 VLTILTLISGTIFYSTVEGLR--PIDALYFSVVTLTTVGYGDFSPQTDFGKIFTILYIFIGIGLVFGFIHKLA 82
Cdd:pfam07885  1 IVLLLVLIFGTVYYLLEEGWEwsFLDALYFSFVTLTTVGYGDIVPLTDAGRLFTIFYILIGIPLFAIFLAVLG 73
PRK10537 PRK10537
voltage-gated potassium channel protein;
12-71 1.17e-08

voltage-gated potassium channel protein;


Pssm-ID: 236711 [Multi-domain]  Cd Length: 393  Bit Score: 50.41  E-value: 1.17e-08
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
3OUF_A        12 VLTILTLISGTIFYSTV--EGLRP-----IDALYFSVVTLTTVGYGDFSPQTDFGKIFTILYIFIGI 71
Cdd:PRK10537 141 VISITSLLFYSTFGALYlgDGFSPpieslSTAFYFSIVTMSTVGYGDIVPVSESARLFTISVIILGI 207
PLN03192 PLN03192
Voltage-dependent potassium channel; Provisional
 24-73 5.58e-08

Voltage-dependent potassium channel; Provisional


Pssm-ID: 215625 [Multi-domain]  Cd Length: 823  Bit Score: 48.71  E-value: 5.58e-08
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
3OUF_A        24 FYSTVEGLRPIDALYFSVVTLTTVGYGDFSPQTDFGKIFTILYIFIGIGL 73
Cdd:PLN03192 242 FRETSLWIRYISAIYWSITTMTTVGYGDLHAVNTIEMIFIIFYMLFNLGL 291
TrkA COG0569
Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain [Inorganic ion ...
 13-78 2.34e-04

Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain [Inorganic ion transport and metabolism, Signal transduction mechanisms];


Pssm-ID: 440335 [Multi-domain]  Cd Length: 296  Bit Score: 38.12  E-value: 2.34e-04
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
3OUF_A       13 LTILTLISGTIFYSTVEGLRPIDALYFSVVTLTTVGYGDFSPQTDFGKIFTILYIFIGIGLVFGFI 78
Cdd:COG0569   1 LLILLLLLVLLFAMGIEGLVLLDALYGLLITLTTVTTLGGGLLDPVTLVAAIFLIGVVIIPLGYTL 66
DUF2254 pfam10011
Predicted membrane protein (DUF2254); Members of this family of bacterial proteins comprises ...
 39-94 9.08e-03

Predicted membrane protein (DUF2254); Members of this family of bacterial proteins comprises various hypothetical and putative membrane proteins. Their exact function, has not, as yet, been defined.


Pssm-ID: 430986  Cd Length: 370  Bit Score: 33.71  E-value: 9.08e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
3OUF_A         39 FSVVTLTTVGYGD-FSPQtdFGKIFTILYIFIGIGLVFGFIHKLAVNVQLPSILSNL 94
Cdd:pfam10011 101 YCLLVLRAVRTGDgFVPQ--LSVTVALLLALVSVGALIYFIHHLARSIQVSNIIARV 155
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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