NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|390981201|pdb|4ETV|A]
View 

Chain A, Ryanodine receptor 2

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
RyR pfam02026
RyR domain; This domain is called RyR for Ryanodine receptor. The domain is found in four ...
 5-94 3.43e-47

RyR domain; This domain is called RyR for Ryanodine receptor. The domain is found in four copies in the ryanodine receptor. The function of this domain is unknown.


:

Pssm-ID: 460419  Cd Length: 90  Bit Score: 149.96  E-value: 3.43e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4ETV_A          5 FNPQPVDTSNITIPEKLEYFINKYAEHSHDKWS*DKLANGWIYGEIYSDSSKIQPL*KPYKLLSEKEKEIYRWPIKESLK 84
Cdd:pfam02026   1 YKPKPVDTSNVTLPEDLEALVEKLAENTHEVWAKEKIEQGWTYGEVRDDAAKTHPCLVPYDLLTEKEKEYDREPARETLK 80

                          90
                  ....*....|
4ETV_A         85 T*LAWGWRIE 94
Cdd:pfam02026  81 TLLALGYTIE 90
RyR super family cl03409
RyR domain; This domain is called RyR for Ryanodine receptor. The domain is found in four ...
 125-208 1.00e-24

RyR domain; This domain is called RyR for Ryanodine receptor. The domain is found in four copies in the ryanodine receptor. The function of this domain is unknown.


The actual alignment was detected with superfamily member pfam02026:

Pssm-ID: 460419  Cd Length: 90  Bit Score: 92.57  E-value: 1.00e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4ETV_A        125 YSPRAID*SNVTLSRDLHA*AE**AENYHNIWAKKKKLELESKGGG------NHPLLVPYDTLTAAEKAKDREKAQDIFK 198
Cdd:pfam02026   1 YKPKPVDTSNVTLPEDLEALVEKLAENTHEVWAKEKIEQGWTYGEVrddaakTHPCLVPYDLLTEKEKEYDREPARETLK 80

                          90
                  ....*....|
4ETV_A        199 FLQISGYVVS 208
Cdd:pfam02026  81 TLLALGYTIE 90
 
Name Accession Description Interval E-value
RyR pfam02026
RyR domain; This domain is called RyR for Ryanodine receptor. The domain is found in four ...
 5-94 3.43e-47

RyR domain; This domain is called RyR for Ryanodine receptor. The domain is found in four copies in the ryanodine receptor. The function of this domain is unknown.


Pssm-ID: 460419  Cd Length: 90  Bit Score: 149.96  E-value: 3.43e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4ETV_A          5 FNPQPVDTSNITIPEKLEYFINKYAEHSHDKWS*DKLANGWIYGEIYSDSSKIQPL*KPYKLLSEKEKEIYRWPIKESLK 84
Cdd:pfam02026   1 YKPKPVDTSNVTLPEDLEALVEKLAENTHEVWAKEKIEQGWTYGEVRDDAAKTHPCLVPYDLLTEKEKEYDREPARETLK 80

                          90
                  ....*....|
4ETV_A         85 T*LAWGWRIE 94
Cdd:pfam02026  81 TLLALGYTIE 90
RyR pfam02026
RyR domain; This domain is called RyR for Ryanodine receptor. The domain is found in four ...
 125-208 1.00e-24

RyR domain; This domain is called RyR for Ryanodine receptor. The domain is found in four copies in the ryanodine receptor. The function of this domain is unknown.


Pssm-ID: 460419  Cd Length: 90  Bit Score: 92.57  E-value: 1.00e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4ETV_A        125 YSPRAID*SNVTLSRDLHA*AE**AENYHNIWAKKKKLELESKGGG------NHPLLVPYDTLTAAEKAKDREKAQDIFK 198
Cdd:pfam02026   1 YKPKPVDTSNVTLPEDLEALVEKLAENTHEVWAKEKIEQGWTYGEVrddaakTHPCLVPYDLLTEKEKEYDREPARETLK 80

                          90
                  ....*....|
4ETV_A        199 FLQISGYVVS 208
Cdd:pfam02026  81 TLLALGYTIE 90
 
Name Accession Description Interval E-value
RyR pfam02026
RyR domain; This domain is called RyR for Ryanodine receptor. The domain is found in four ...
 5-94 3.43e-47

RyR domain; This domain is called RyR for Ryanodine receptor. The domain is found in four copies in the ryanodine receptor. The function of this domain is unknown.


Pssm-ID: 460419  Cd Length: 90  Bit Score: 149.96  E-value: 3.43e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4ETV_A          5 FNPQPVDTSNITIPEKLEYFINKYAEHSHDKWS*DKLANGWIYGEIYSDSSKIQPL*KPYKLLSEKEKEIYRWPIKESLK 84
Cdd:pfam02026   1 YKPKPVDTSNVTLPEDLEALVEKLAENTHEVWAKEKIEQGWTYGEVRDDAAKTHPCLVPYDLLTEKEKEYDREPARETLK 80

                          90
                  ....*....|
4ETV_A         85 T*LAWGWRIE 94
Cdd:pfam02026  81 TLLALGYTIE 90
RyR pfam02026
RyR domain; This domain is called RyR for Ryanodine receptor. The domain is found in four ...
 125-208 1.00e-24

RyR domain; This domain is called RyR for Ryanodine receptor. The domain is found in four copies in the ryanodine receptor. The function of this domain is unknown.


Pssm-ID: 460419  Cd Length: 90  Bit Score: 92.57  E-value: 1.00e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4ETV_A        125 YSPRAID*SNVTLSRDLHA*AE**AENYHNIWAKKKKLELESKGGG------NHPLLVPYDTLTAAEKAKDREKAQDIFK 198
Cdd:pfam02026   1 YKPKPVDTSNVTLPEDLEALVEKLAENTHEVWAKEKIEQGWTYGEVrddaakTHPCLVPYDLLTEKEKEYDREPARETLK 80

                          90
                  ....*....|
4ETV_A        199 FLQISGYVVS 208
Cdd:pfam02026  81 TLLALGYTIE 90
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH