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Conserved domains on  [gi|1126132785|pdb|5G3Y|A]
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Chain A, ADENYLATE KINSE

Protein Classification

nucleoside monophosphate kinase( domain architecture ID 11478412)

nucleoside monophosphate kinase catalyzes the transfer of the terminal phosphoryl group from a nucleoside triphosphate, usually ATP, to a nucleoside monophosphate

CATH:  3.40.50.300
EC:  2.7.4.-
Gene Ontology:  GO:0050145|GO:0016310|GO:0046872
PubMed:  2841070
SCOP:  3002021

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
adk PRK00279
adenylate kinase; Reviewed
 1-214 8.60e-162

adenylate kinase; Reviewed


:

Pssm-ID: 234711 [Multi-domain]  Cd Length: 215  Bit Score: 445.36  E-value: 8.60e-162
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5G3Y_A         1 MNLILLGPPGAGKGTQAEKIVEEYGIPHISTGDMFRAAIKEGTELGLKAKEYMDKGELVPDEVTIGLVKERLSQPDCKKG 80
Cdd:PRK00279   1 MRLILLGPPGAGKGTQAKFIAEKYGIPHISTGDMLRAAVKAGTELGKEAKSYMDAGELVPDEIVIGLVKERLAQPDCKNG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5G3Y_A        81 FLLDGFPRTVAQAEALDKILKELGIKLDAVINIEVPREELLERLTGRRVCRQCGATYHVIFNPPKVEGVCDKCGGELYQR 160
Cdd:PRK00279  81 FLLDGFPRTIPQAEALDEMLKELGIKLDAVIEIDVPDEELVERLSGRRICPACGRTYHVKFNPPKVEGKCDVCGEELIQR 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
5G3Y_A       161 SDDNEETVSNRLDVYEDQTAPLIDYYEKKGLLKNIDGDQDIDAVFADIKAALGR 214
Cdd:PRK00279 161 ADDNEETVRKRLEVYHKQTAPLIDYYKKKGKLKKIDGTGSIDEVFADILKALGK 214
 
Name Accession Description Interval E-value
adk PRK00279
adenylate kinase; Reviewed
 1-214 8.60e-162

adenylate kinase; Reviewed


Pssm-ID: 234711 [Multi-domain]  Cd Length: 215  Bit Score: 445.36  E-value: 8.60e-162
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5G3Y_A         1 MNLILLGPPGAGKGTQAEKIVEEYGIPHISTGDMFRAAIKEGTELGLKAKEYMDKGELVPDEVTIGLVKERLSQPDCKKG 80
Cdd:PRK00279   1 MRLILLGPPGAGKGTQAKFIAEKYGIPHISTGDMLRAAVKAGTELGKEAKSYMDAGELVPDEIVIGLVKERLAQPDCKNG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5G3Y_A        81 FLLDGFPRTVAQAEALDKILKELGIKLDAVINIEVPREELLERLTGRRVCRQCGATYHVIFNPPKVEGVCDKCGGELYQR 160
Cdd:PRK00279  81 FLLDGFPRTIPQAEALDEMLKELGIKLDAVIEIDVPDEELVERLSGRRICPACGRTYHVKFNPPKVEGKCDVCGEELIQR 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
5G3Y_A       161 SDDNEETVSNRLDVYEDQTAPLIDYYEKKGLLKNIDGDQDIDAVFADIKAALGR 214
Cdd:PRK00279 161 ADDNEETVRKRLEVYHKQTAPLIDYYKKKGKLKKIDGTGSIDEVFADILKALGK 214
Adk COG0563
Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or ...
 1-212 4.81e-159

Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or related kinase is part of the Pathway/BioSystem: Pyrimidine biosynthesis


Pssm-ID: 440329 [Multi-domain]  Cd Length: 212  Bit Score: 438.41  E-value: 4.81e-159
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5G3Y_A        1 MNLILLGPPGAGKGTQAEKIVEEYGIPHISTGDMFRAAIKEGTELGLKAKEYMDKGELVPDEVTIGLVKERLSQPDCKKG 80
Cdd:COG0563   1 MRIILLGPPGAGKGTQAKRLAEKYGIPHISTGDMLRAAVKAGTELGKKAKEYMDAGELVPDEIVIGLVKERLAQPDCANG 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5G3Y_A       81 FLLDGFPRTVAQAEALDKILKELGIKLDAVINIEVPREELLERLTGRRVCRQCGATYHVIFNPPKVEGVCDKCGGELYQR 160
Cdd:COG0563  81 FILDGFPRTVAQAEALDELLAELGIKLDAVIELDVDDEELVERLSGRRVCPNCGATYHVKFNPPKVEGVCDKCGGELVQR 160

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|..
5G3Y_A      161 SDDNEETVSNRLDVYEDQTAPLIDYYEKKGLLKNIDGDQDIDAVFADIKAAL 212
Cdd:COG0563 161 ADDNEETVRKRLEVYHEQTAPLIDYYRKKGKLVEIDGEGSIEEVTADILAIL 212
adk TIGR01351
adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ...
 2-213 2.78e-119

adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ATP as a phosphate donor for AMP. Most members of this family are known or believed to be adenylate kinase. However, some members accept other nucleotide triphosphates as donors, may be unable to use ATP, and may fail to complement adenylate kinase mutants. An example of a nucleoside-triphosphate--adenylate kinase (EC 2.7.4.10) is SP|Q9UIJ7, a GTP:AMP phosphotransferase. This family is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Nucleotide and nucleoside interconversions]


Pssm-ID: 273569 [Multi-domain]  Cd Length: 210  Bit Score: 337.67  E-value: 2.78e-119
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5G3Y_A          2 NLILLGPPGAGKGTQAEKIVEEYGIPHISTGDMFRAAIKEGTELGLKAKEYMDKGELVPDEVTIGLVKERLSQ-PDCKKG 80
Cdd:TIGR01351   1 RLVLLGPPGSGKGTQAKRIAEKYGLPHISTGDLLRAEIKAGTPLGKKAKEYMEKGELVPDEIVNQLVKERLTQnDDNENG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5G3Y_A         81 FLLDGFPRTVAQAEALDKILKElgiKLDAVINIEVPREELLERLTGRRVCRQCGATYHVIFNPPKVEGVCDKCGGELYQR 160
Cdd:TIGR01351  81 FILDGFPRTLSQAEALDALLEE---PIDAVIELDVPDEELVERLSGRRICPSCGRVYHLKFNPPKVPGCDDCTGELLVQR 157

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
5G3Y_A        161 SDDNEETVSNRLDVYEDQTAPLIDYYEKKGLLKNIDGDQDIDAVFADIKAALG 213
Cdd:TIGR01351 158 EDDTEEVVKKRLEVYKEQTEPLIDYYKKRGILVQIDGNGPIDEVWKRILEALK 210
ADK pfam00406
Adenylate kinase;
5-189 1.42e-117

Adenylate kinase;


Pssm-ID: 395329 [Multi-domain]  Cd Length: 184  Bit Score: 332.35  E-value: 1.42e-117
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5G3Y_A          5 LLGPPGAGKGTQAEKIVEEYGIPHISTGDMFRAAIKEGTELGLKAKEYMDKGELVPDEVTIGLVKERLSQPDCKKGFLLD 84
Cdd:pfam00406   1 LLGPPGAGKGTQAEKIVQKYGLPHLSTGDLLRAEIKSGTELGKEAKEYMDKGELVPDEVVVGLVKERLEQNDCKNGFLLD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5G3Y_A         85 GFPRTVAQAEALDKILkELGIKLDAVINIEVPREELLERLTGRRVCRQCGATYHVIFNPPKVEGVCDKCGGELYQRSDDN 164
Cdd:pfam00406  81 GFPRTVPQAEALEELL-ERGIKLDYVIEFDVPDEVLVERLTGRRIHPNSGRSYHLEFNPPKVPGKDDVTGEPLVQRSDDN 159

                         170       180
                  ....*....|....*....|....*
5G3Y_A        165 EETVSNRLDVYEDQTAPLIDYYEKK 189
Cdd:pfam00406 160 EETVKKRLETYHKQTKPLIDYYKKK 184
ADK cd01428
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine ...
 2-204 2.32e-110

Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for homeostasis of adenosine phosphates.


Pssm-ID: 238713 [Multi-domain]  Cd Length: 194  Bit Score: 314.56  E-value: 2.32e-110
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5G3Y_A        2 NLILLGPPGAGKGTQAEKIVEEYGIPHISTGDMFRAAIKEGTELGLKAKEYMDKGELVPDEVTIGLVKERLSQPDCKKGF 81
Cdd:cd01428   1 RILLLGPPGSGKGTQAERLAKKYGLPHISTGDLLREEIASGTELGKKAKEYIDSGKLVPDEIVIKLLKERLKKPDCKKGF 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5G3Y_A       82 LLDGFPRTVAQAEALDKILKElGIKLDAVINIEVPREELLERLTGRRVCRQCGATYHVifnppkveGVCDKCGGELYQRS 161
Cdd:cd01428  81 ILDGFPRTVDQAEALDELLDE-GIKPDKVIELDVPDEVLIERILGRRICPVSGRVYHL--------GKDDVTGEPLSQRS 151

                       170       180       190       200
                ....*....|....*....|....*....|....*....|...
5G3Y_A      162 DDNEETVSNRLDVYEDQTAPLIDYYEKKGLLKNIDGDQDIDAV 204
Cdd:cd01428 152 DDNEETIKKRLEVYKEQTAPLIDYYKKKGKLVEIDGSGDIDEV 194
 
Name Accession Description Interval E-value
adk PRK00279
adenylate kinase; Reviewed
 1-214 8.60e-162

adenylate kinase; Reviewed


Pssm-ID: 234711 [Multi-domain]  Cd Length: 215  Bit Score: 445.36  E-value: 8.60e-162
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5G3Y_A         1 MNLILLGPPGAGKGTQAEKIVEEYGIPHISTGDMFRAAIKEGTELGLKAKEYMDKGELVPDEVTIGLVKERLSQPDCKKG 80
Cdd:PRK00279   1 MRLILLGPPGAGKGTQAKFIAEKYGIPHISTGDMLRAAVKAGTELGKEAKSYMDAGELVPDEIVIGLVKERLAQPDCKNG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5G3Y_A        81 FLLDGFPRTVAQAEALDKILKELGIKLDAVINIEVPREELLERLTGRRVCRQCGATYHVIFNPPKVEGVCDKCGGELYQR 160
Cdd:PRK00279  81 FLLDGFPRTIPQAEALDEMLKELGIKLDAVIEIDVPDEELVERLSGRRICPACGRTYHVKFNPPKVEGKCDVCGEELIQR 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
5G3Y_A       161 SDDNEETVSNRLDVYEDQTAPLIDYYEKKGLLKNIDGDQDIDAVFADIKAALGR 214
Cdd:PRK00279 161 ADDNEETVRKRLEVYHKQTAPLIDYYKKKGKLKKIDGTGSIDEVFADILKALGK 214
Adk COG0563
Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or ...
 1-212 4.81e-159

Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or related kinase is part of the Pathway/BioSystem: Pyrimidine biosynthesis


Pssm-ID: 440329 [Multi-domain]  Cd Length: 212  Bit Score: 438.41  E-value: 4.81e-159
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5G3Y_A        1 MNLILLGPPGAGKGTQAEKIVEEYGIPHISTGDMFRAAIKEGTELGLKAKEYMDKGELVPDEVTIGLVKERLSQPDCKKG 80
Cdd:COG0563   1 MRIILLGPPGAGKGTQAKRLAEKYGIPHISTGDMLRAAVKAGTELGKKAKEYMDAGELVPDEIVIGLVKERLAQPDCANG 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5G3Y_A       81 FLLDGFPRTVAQAEALDKILKELGIKLDAVINIEVPREELLERLTGRRVCRQCGATYHVIFNPPKVEGVCDKCGGELYQR 160
Cdd:COG0563  81 FILDGFPRTVAQAEALDELLAELGIKLDAVIELDVDDEELVERLSGRRVCPNCGATYHVKFNPPKVEGVCDKCGGELVQR 160

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|..
5G3Y_A      161 SDDNEETVSNRLDVYEDQTAPLIDYYEKKGLLKNIDGDQDIDAVFADIKAAL 212
Cdd:COG0563 161 ADDNEETVRKRLEVYHEQTAPLIDYYRKKGKLVEIDGEGSIEEVTADILAIL 212
adk TIGR01351
adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ...
 2-213 2.78e-119

adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ATP as a phosphate donor for AMP. Most members of this family are known or believed to be adenylate kinase. However, some members accept other nucleotide triphosphates as donors, may be unable to use ATP, and may fail to complement adenylate kinase mutants. An example of a nucleoside-triphosphate--adenylate kinase (EC 2.7.4.10) is SP|Q9UIJ7, a GTP:AMP phosphotransferase. This family is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Nucleotide and nucleoside interconversions]


Pssm-ID: 273569 [Multi-domain]  Cd Length: 210  Bit Score: 337.67  E-value: 2.78e-119
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5G3Y_A          2 NLILLGPPGAGKGTQAEKIVEEYGIPHISTGDMFRAAIKEGTELGLKAKEYMDKGELVPDEVTIGLVKERLSQ-PDCKKG 80
Cdd:TIGR01351   1 RLVLLGPPGSGKGTQAKRIAEKYGLPHISTGDLLRAEIKAGTPLGKKAKEYMEKGELVPDEIVNQLVKERLTQnDDNENG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5G3Y_A         81 FLLDGFPRTVAQAEALDKILKElgiKLDAVINIEVPREELLERLTGRRVCRQCGATYHVIFNPPKVEGVCDKCGGELYQR 160
Cdd:TIGR01351  81 FILDGFPRTLSQAEALDALLEE---PIDAVIELDVPDEELVERLSGRRICPSCGRVYHLKFNPPKVPGCDDCTGELLVQR 157

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
5G3Y_A        161 SDDNEETVSNRLDVYEDQTAPLIDYYEKKGLLKNIDGDQDIDAVFADIKAALG 213
Cdd:TIGR01351 158 EDDTEEVVKKRLEVYKEQTEPLIDYYKKRGILVQIDGNGPIDEVWKRILEALK 210
ADK pfam00406
Adenylate kinase;
5-189 1.42e-117

Adenylate kinase;


Pssm-ID: 395329 [Multi-domain]  Cd Length: 184  Bit Score: 332.35  E-value: 1.42e-117
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5G3Y_A          5 LLGPPGAGKGTQAEKIVEEYGIPHISTGDMFRAAIKEGTELGLKAKEYMDKGELVPDEVTIGLVKERLSQPDCKKGFLLD 84
Cdd:pfam00406   1 LLGPPGAGKGTQAEKIVQKYGLPHLSTGDLLRAEIKSGTELGKEAKEYMDKGELVPDEVVVGLVKERLEQNDCKNGFLLD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5G3Y_A         85 GFPRTVAQAEALDKILkELGIKLDAVINIEVPREELLERLTGRRVCRQCGATYHVIFNPPKVEGVCDKCGGELYQRSDDN 164
Cdd:pfam00406  81 GFPRTVPQAEALEELL-ERGIKLDYVIEFDVPDEVLVERLTGRRIHPNSGRSYHLEFNPPKVPGKDDVTGEPLVQRSDDN 159

                         170       180
                  ....*....|....*....|....*
5G3Y_A        165 EETVSNRLDVYEDQTAPLIDYYEKK 189
Cdd:pfam00406 160 EETVKKRLETYHKQTKPLIDYYKKK 184
ADK cd01428
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine ...
 2-204 2.32e-110

Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for homeostasis of adenosine phosphates.


Pssm-ID: 238713 [Multi-domain]  Cd Length: 194  Bit Score: 314.56  E-value: 2.32e-110
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5G3Y_A        2 NLILLGPPGAGKGTQAEKIVEEYGIPHISTGDMFRAAIKEGTELGLKAKEYMDKGELVPDEVTIGLVKERLSQPDCKKGF 81
Cdd:cd01428   1 RILLLGPPGSGKGTQAERLAKKYGLPHISTGDLLREEIASGTELGKKAKEYIDSGKLVPDEIVIKLLKERLKKPDCKKGF 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5G3Y_A       82 LLDGFPRTVAQAEALDKILKElGIKLDAVINIEVPREELLERLTGRRVCRQCGATYHVifnppkveGVCDKCGGELYQRS 161
Cdd:cd01428  81 ILDGFPRTVDQAEALDELLDE-GIKPDKVIELDVPDEVLIERILGRRICPVSGRVYHL--------GKDDVTGEPLSQRS 151

                       170       180       190       200
                ....*....|....*....|....*....|....*....|...
5G3Y_A      162 DDNEETVSNRLDVYEDQTAPLIDYYEKKGLLKNIDGDQDIDAV 204
Cdd:cd01428 152 DDNEETIKKRLEVYKEQTAPLIDYYKKKGKLVEIDGSGDIDEV 194
PRK14530 PRK14530
adenylate kinase; Provisional
 2-212 1.72e-85

adenylate kinase; Provisional


Pssm-ID: 237747 [Multi-domain]  Cd Length: 215  Bit Score: 252.40  E-value: 1.72e-85
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5G3Y_A         2 NLILLGPPGAGKGTQAEKIVEEYGIPHISTGDMFRA----AIKE-GTELGlKAKEYMDKGELVPDEVTIGLVKERLSQPD 76
Cdd:PRK14530   5 RILLLGAPGAGKGTQSSNLAEEFGVEHVTTGDALRAnkqmDISDmDTEYD-TPGEYMDAGELVPDAVVNEIVEEALSDAD 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5G3Y_A        77 ckkGFLLDGFPRTVAQAEALDKIlkelgIKLDAVINIEVPREELLERLTGRRVCRQCGATYHVIFNPPKVEGVCDKCGGE 156
Cdd:PRK14530  84 ---GFVLDGYPRNLEQAEYLESI-----TDLDVVLYLDVSEEELVDRLTGRRVCPDCGANYHVEFNQPEEEGVCDECGGE 155

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
5G3Y_A       157 LYQRSDDNEETVSNRLDVYEDQTAPLIDYYEKKGLLKNIDGDQDIDAVFADIKAAL 212
Cdd:PRK14530 156 LIQRDDDTEETVRERLDVFEENTEPVIEHYRDQGVLVEVDGEQTPDEVWADIQDAI 211
adk PRK02496
adenylate kinase; Provisional
 3-213 1.32e-83

adenylate kinase; Provisional


Pssm-ID: 179433 [Multi-domain]  Cd Length: 184  Bit Score: 246.59  E-value: 1.32e-83
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5G3Y_A         3 LILLGPPGAGKGTQAEKIVEEYGIPHISTGDMFRAAIKEGTELGLKAKEYMDKGELVPDEVTIGLVKERLSQPDCKKGFL 82
Cdd:PRK02496   4 LIFLGPPGAGKGTQAVVLAEHLHIPHISTGDILRQAIKEQTPLGIKAQGYMDKGELVPDQLVLDLVQERLQQPDAANGWI 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5G3Y_A        83 LDGFPRTVAQAEALDKILKELGIKLDAVINIEVPREELLERLTGRrvcrqcgatyhvifnppkvegvcdkcggelyQRSD 162
Cdd:PRK02496  84 LDGFPRKVTQAAFLDELLQEIGQSGERVVNLDVPDDVVVERLLAR-------------------------------GRKD 132

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
5G3Y_A       163 DNEETVSNRLDVYEDQTAPLIDYYEKKGLLKNIDGDQDIDAVFADIKAALG 213
Cdd:PRK02496 133 DTEEVIRRRLEVYREQTAPLIDYYRDRQKLLTIDGNQSVEAVTTELKAALA 183
PLN02674 PLN02674
adenylate kinase
 3-212 5.60e-77

adenylate kinase


Pssm-ID: 178279 [Multi-domain]  Cd Length: 244  Bit Score: 232.08  E-value: 5.60e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5G3Y_A         3 LILLGPPGAGKGTQAEKIVEEYGIPHISTGDMFRAAIKEGTELGLKAKEYMDKGELVPDEVTIGLVKERLSQPDCKKGFL 82
Cdd:PLN02674  34 LILIGPPGSGKGTQSPIIKDEYCLCHLATGDMLRAAVAAKTPLGIKAKEAMDKGELVSDDLVVGIIDEAMKKPSCQKGFI 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5G3Y_A        83 LDGFPRTVAQAEALDKILKELGIKLDAVINIEVPREELLERLTGRRVCRQCGATYHVIFNPPKVEGVCDKCGGELYQRSD 162
Cdd:PLN02674 114 LDGFPRTVVQAQKLDEMLAKQGAKIDKVLNFAIDDAILEERITGRWIHPSSGRTYHTKFAPPKVPGVDDVTGEPLIQRKD 193

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
5G3Y_A       163 DNEETVSNRLDVYEDQTAPLIDYYEKKGLLKNIDGDQDIDAVFADIKAAL 212
Cdd:PLN02674 194 DTAAVLKSRLEAFHKQTEPVIDYYAKKGVVANLHAEKPPKEVTAEVQKAL 243
PRK14532 PRK14532
adenylate kinase; Provisional
 1-214 1.02e-73

adenylate kinase; Provisional


Pssm-ID: 184729 [Multi-domain]  Cd Length: 188  Bit Score: 221.62  E-value: 1.02e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5G3Y_A         1 MNLILLGPPGAGKGTQAEKIVEEYGIPHISTGDMFRAAIKEGTELGLKAKEYMDKGELVPDEVTIGLVKERLSQPDCKKG 80
Cdd:PRK14532   1 MNLILFGPPAAGKGTQAKRLVEERGMVQLSTGDMLRAAIASGSELGQRVKGIMDRGELVSDEIVIALIEERLPEAEAAGG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5G3Y_A        81 FLLDGFPRTVAQAEALDKILKELGIKLDAVINIEVPREELLERLTGRrvcrqcgatyhvifnppkvegvcdkcgGELYQR 160
Cdd:PRK14532  81 AIFDGFPRTVAQAEALDKMLASRGQKIDVVIRLKVDDEALIERIVKR---------------------------FEEQGR 133

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
5G3Y_A       161 SDDNEETVSNRLDVYEDQTAPLIDYYEKKGLLKNIDGDQDIDAVFADIKAALGR 214
Cdd:PRK14532 134 PDDNPEVFVTRLDAYNAQTAPLLPYYAGQGKLTEVDGMGSIEAVAASIDAALEG 187
PRK14528 PRK14528
adenylate kinase; Provisional
 2-212 4.77e-73

adenylate kinase; Provisional


Pssm-ID: 172994 [Multi-domain]  Cd Length: 186  Bit Score: 219.88  E-value: 4.77e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5G3Y_A         2 NLILLGPPGAGKGTQAEKIVEEYGIPHISTGDMFRAAIKEGTELGLKAKEYMDKGELVPDEVTIGLVKERLSQPDCKKGF 81
Cdd:PRK14528   3 NIIFMGPPGAGKGTQAKILCERLSIPQISTGDILREAVKNQTAMGIEAKRYMDAGDLVPDSVVIGIIKDRIREADCKNGF 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5G3Y_A        82 LLDGFPRTVAQAEALDKILKELGIKLDAVINIEVPREELLERLTGRRVcrqcgatyhvifnppkVEGvcdkcggelyqRS 161
Cdd:PRK14528  83 LLDGFPRTVEQADALDALLKNEGKSIDKAINLEVPDGELLKRLLGRAE----------------IEG-----------RA 135

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
5G3Y_A       162 DDNEETVSNRLDVYEDQTAPLIDYYEKKGLLKNIDGDQDIDAVFADIKAAL 212
Cdd:PRK14528 136 DDNEATIKNRLDNYNKKTLPLLDFYAAQKKLSQVNGVGSLEEVTSLIQKEL 186
PRK13808 PRK13808
adenylate kinase; Provisional
 1-213 2.18e-71

adenylate kinase; Provisional


Pssm-ID: 172341 [Multi-domain]  Cd Length: 333  Bit Score: 220.53  E-value: 2.18e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5G3Y_A         1 MNLILLGPPGAGKGTQAEKIVEEYGIPHISTGDMFRAAIKEGTELGLKAKEYMDKGELVPDEVTIGLVKERLSQPDCKKG 80
Cdd:PRK13808   1 MRLILLGPPGAGKGTQAQRLVQQYGIVQLSTGDMLRAAVAAGTPVGLKAKDIMASGGLVPDEVVVGIISDRIEQPDAANG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5G3Y_A        81 FLLDGFPRTVAQAEALDKILKELGIKLDAVINIEVPREELLERLTgRRVC--RQCGatyhvifnppkvEGVcdkcggely 158
Cdd:PRK13808  81 FILDGFPRTVPQAEALDALLKDKQLKLDAVVELRVNEGALLARVE-TRVAemRARG------------EEV--------- 138

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
5G3Y_A       159 qRSDDNEETVSNRLDVYEDQTAPLIDYYEKKGLLKNIDGDQDIDAVFADIKAALG 213
Cdd:PRK13808 139 -RADDTPEVLAKRLASYRAQTEPLVHYYSEKRKLLTVDGMMTIDEVTREIGRVLA 192
PRK14527 PRK14527
adenylate kinase; Provisional
 3-213 1.50e-67

adenylate kinase; Provisional


Pssm-ID: 237745 [Multi-domain]  Cd Length: 191  Bit Score: 206.18  E-value: 1.50e-67
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5G3Y_A         3 LILLGPPGAGKGTQAEKIVEEYGIPHISTGDMFRAAIKEGTELGLKAKEYMDKGELVPDEVTIGLVKERLSQPDCKKgFL 82
Cdd:PRK14527   9 VIFLGPPGAGKGTQAERLAQELGLKKLSTGDILRDHVARGTELGQRAKPIMEAGDLVPDELILALIRDELAGMEPVR-VI 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5G3Y_A        83 LDGFPRTVAQAEALDKILKELGIKLDAVINIEVPREELLERLTGRrvcrqcgatyhvifnppkvegvcdkcgGELYQRSD 162
Cdd:PRK14527  88 FDGFPRTLAQAEALDRLLEELGARLLAVVLLEVPDEELIRRIVER---------------------------ARQEGRSD 140

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
5G3Y_A       163 DNEETVSNRLDVYEDQTAPLIDYYEKKGLLKNIDGDQDIDAVFADIKAALG 213
Cdd:PRK14527 141 DNEETVRRRQQVYREQTQPLVDYYEARGHLKRVDGLGTPDEVYARILKALG 191
PRK14526 PRK14526
adenylate kinase; Provisional
 1-204 8.16e-64

adenylate kinase; Provisional


Pssm-ID: 172992 [Multi-domain]  Cd Length: 211  Bit Score: 197.38  E-value: 8.16e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5G3Y_A         1 MNLILLGPPGAGKGTQAEKIVEEYGIPHISTGDMFRAAIKEGTELGLKAKEYMDKGELVPDEVTIGLVKERLSQPDCKKG 80
Cdd:PRK14526   1 MKLVFLGPPGSGKGTIAKILSNELNYYHISTGDLFRENILNSTPLGKEIKQIVENGQLVPDSITIKIVEDKINTIKNNDN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5G3Y_A        81 FLLDGFPRTVAQAEALDKILKELGIkldavINIEVPREELLERLTGRRVCRQCGATYHVIFNPPKVEGVCDKCGGELYQR 160
Cdd:PRK14526  81 FILDGFPRNINQAKALDKFLPNIKI-----INFLIDEELLIKRLSGRRICKSCNNIFNIYTLPTKEKGICDVCKGDLYQR 155

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
5G3Y_A       161 SDDNEETVSNRLDVYEDQTAPLIDYYEKKGLLKNIDGDQDIDAV 204
Cdd:PRK14526 156 KDDKEESLKTRLQEYKLQTKPLIEFYSKCNRLNNIDASKDIDEV 199
PRK14531 PRK14531
adenylate kinase; Provisional
 3-213 9.85e-59

adenylate kinase; Provisional


Pssm-ID: 172997 [Multi-domain]  Cd Length: 183  Bit Score: 183.47  E-value: 9.85e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5G3Y_A         3 LILLGPPGAGKGTQAEKIVEEYGIPHISTGDMFRAAIKEGTELGLKAKEYMDKGELVPDEVTIGLVKERLsQPDCKKGFL 82
Cdd:PRK14531   5 LLFLGPPGAGKGTQAARLCAAHGLRHLSTGDLLRSEVAAGSALGQEAEAVMNRGELVSDALVLAIVESQL-KALNSGGWL 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5G3Y_A        83 LDGFPRTVAQAEALDKILKELGIKLDAVINIEVPREELLERLTGRrvcrqcgatyhvifnppkvegvcdkcggelyQRSD 162
Cdd:PRK14531  84 LDGFPRTVAQAEALEPLLEELKQPIEAVVLLELDDAVLIERLLAR-------------------------------GRAD 132

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
5G3Y_A       163 DNEETVSNRLDVYEDQTAPLIDYYEKKGLLKNIDGDQDIDAVFADIKAALG 213
Cdd:PRK14531 133 DNEAVIRNRLEVYREKTAPLIDHYRQRGLLQSVEAQGSIEAITERIEKVLA 183
PLN02842 PLN02842
nucleotide kinase
 7-212 1.03e-58

nucleotide kinase


Pssm-ID: 178435 [Multi-domain]  Cd Length: 505  Bit Score: 192.77  E-value: 1.03e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5G3Y_A         7 GPPGAGKGTQAEKIVEEYGIPHISTGDMFRAAIKEGTELGLKAKEYMDKGELVPDEVTIGLVKERLSQPD-CKKGFLLDG 85
Cdd:PLN02842   4 GAPASGKGTQCELIVHKFGLVHISTGDLLRAEVSAGTDIGKRAKEFMNSGRLVPDEIVIAMVTGRLSREDaKEKGWLLDG 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5G3Y_A        86 FPRTVAQAEALDKilkeLGIKLDAVINIEVPREELLERLTGRRVCRQCGATYHVIFNPPKVEGVcdkcGGELYQRSDDNE 165
Cdd:PLN02842  84 YPRSFAQAQSLEK----LKIRPDIFILLDVPDEILIDRCVGRRLDPVTGKIYHIKNFPPESEEI----KARLITRPDDTE 155

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
5G3Y_A       166 ETVSNRLDVYEDQTAPLIDYYEKkgLLKNIDGDQDIDAVFADIKAAL 212
Cdd:PLN02842 156 EKVKARLQIYKKNAEAILSTYSD--IMVKIDGNRPKEVVFEEISSLL 200
PRK14529 PRK14529
adenylate kinase; Provisional
 1-213 3.00e-58

adenylate kinase; Provisional


Pssm-ID: 237746 [Multi-domain]  Cd Length: 223  Bit Score: 183.38  E-value: 3.00e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5G3Y_A         1 MNLILLGPPGAGKGTQAEKIVEEYGIPHISTGDMFRAAIKEGTELGLKAKEYMDKGELVPDEVTIGLVKERLSQPDcKKG 80
Cdd:PRK14529   1 MNILIFGPNGSGKGTQGALVKKKYDLAHIESGAIFREHIGGGTELGKKAKEYIDRGDLVPDDITIPMILETLKQDG-KNG 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5G3Y_A        81 FLLDGFPRTVAQAEALDKILKELGIKLDAVINIEVPREELLERLTGRRVCRQ-CGATYHVIFNPPKVEG-VCDKCGGELY 158
Cdd:PRK14529  80 WLLDGFPRNKVQAEKLWEALQKEGMKLDYVIEILLPREVAKNRIMGRRLCKNdNNHPNNIFIDAIKPDGdVCRVCGGELS 159

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
5G3Y_A       159 QRSDD-NEETVSNRLDVY---EDQTAPLIDYYE---KKGLLKNI--DGDQDIDAVFADIKAALG 213
Cdd:PRK14529 160 TRADDqDEEAINKRHDIYydtETGTLAAAYFFKdlaAKGSTKYIelDGEGSIDEIKETLLKQLS 223
PLN02459 PLN02459
probable adenylate kinase
 2-196 5.17e-55

probable adenylate kinase


Pssm-ID: 215253 [Multi-domain]  Cd Length: 261  Bit Score: 176.58  E-value: 5.17e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5G3Y_A         2 NLILLGPPGAGKGTQAEKIVEEYGIPHISTGDMFRAAIKEGTELGLKAKEYMDKGELVPDEVTIGLVKERLSQPDCK--K 79
Cdd:PLN02459  31 NWVFLGCPGVGKGTYASRLSKLLGVPHIATGDLVREEIKSSGPLGAQLKEIVNQGKLVPDEIIFSLLSKRLEAGEEEgeS 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5G3Y_A        80 GFLLDGFPRTVAQAEALDKIlkelgIKLDAVINIEVPREELLERLTGRRVCRQCGATYHV-------------IFNPPKV 146
Cdd:PLN02459 111 GFILDGFPRTVRQAEILEGV-----TDIDLVVNLKLREEVLVEKCLGRRICSECGKNFNVadidlkgedgrpgIVMPPLL 185

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
5G3Y_A       147 EGvcDKCGGELYQRSDDNEETVSNRLDVYEDQTAPLIDYYEKKGLLKNID 196
Cdd:PLN02459 186 PP--PECASKLITRADDTEEVVKARLRVYKEESQPVEDFYRKRGKLLEFE 233
UMP_CMP_kin_fam TIGR01359
UMP-CMP kinase family; This subfamily of the adenylate kinase superfamily contains examples of ...
 3-212 1.14e-51

UMP-CMP kinase family; This subfamily of the adenylate kinase superfamily contains examples of UMP-CMP kinase, as well as others proteins with unknown specificity, some currently designated adenylate kinase. All known members are eukaryotic.


Pssm-ID: 273576 [Multi-domain]  Cd Length: 185  Bit Score: 165.24  E-value: 1.14e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5G3Y_A          3 LILLGPPGAGKGTQAEKIVEEYGIPHISTGDMFRAAIK-EGTELGLKAKEYMDKGELVPDEVTIGLVKERLSQPDCKKGF 81
Cdd:TIGR01359   2 VFVLGGPGSGKGTQCAKIVENFGFTHLSAGDLLRAEIKrEGSENGSLIESYIKEGKIVPSEVTVELLKKAIQEDGSSKKF 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5G3Y_A         82 LLDGFPRTVAQAEALDKILKElGIKLDAVINIEVPREELLERLTGRrvcrqcgatyhvifnppkvegvcdkcgGELYQRS 161
Cdd:TIGR01359  82 LIDGFPRNEENLEAWEKLMDN-KVNFKFVLFFDCPEETMIKRLLKR---------------------------GQTSGRV 133

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
5G3Y_A        162 DDNEETVSNRLDVYEDQTAPLIDYYEKKGLLKNIDGDQDIDAVFADIKAAL 212
Cdd:TIGR01359 134 DDNIETLKKRFRTYNEETLPIIEHFENKGKVKEINAEGSVEEVFEDVEKIF 184
PTZ00088 PTZ00088
adenylate kinase 1; Provisional
 1-190 8.14e-51

adenylate kinase 1; Provisional


Pssm-ID: 240262 [Multi-domain]  Cd Length: 229  Bit Score: 164.59  E-value: 8.14e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5G3Y_A         1 MNLILLGPPGAGKGTQAEKIVEEYGIPHISTGDMFRAAIKEGTELGLKAKEYMDKGELVPDEVTIGLVKERLSQP--DCK 78
Cdd:PTZ00088   7 LKIVLFGAPGVGKGTFAEILSKKENLKHINMGNILREEIKAKTTIGKEIQKVVTSGNLVPDNLVIAIVKDEIAKVtdDCF 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5G3Y_A        79 KGFLLDGFPRTVAQAEALDKIlkelgIKLDAVINIEVPREELLERLTGRRVCRQCGATYHVI------FNPPKV--EGVC 150
Cdd:PTZ00088  87 KGFILDGFPRNLKQCKELGKI-----TNIDLFVNIYLPRNILIKKLLGRRICNTCNRNFNIAhirsdpYDMPPIlpPADC 161

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
5G3Y_A       151 DKCGG--ELYQRSDDNEETVSNRLDVYEDQTAPLIDYYEKKG 190
Cdd:PTZ00088 162 EGCKGnpKLQKRSDDTEEIVAHRLNTYESTNSPIIQFFKNEN 203
aden_kin_iso1 TIGR01360
adenylate kinase, isozyme 1 subfamily; Members of this family are adenylate kinase, EC 2.7.4.3. ...
 5-212 4.60e-45

adenylate kinase, isozyme 1 subfamily; Members of this family are adenylate kinase, EC 2.7.4.3. This clade is found only in eukaryotes and includes human adenylate kinase isozyme 1 (myokinase). Within the adenylate kinase superfamily, this set appears specifically closely related to a subfamily of eukaryotic UMP-CMP kinases (TIGR01359), rather than to the large clade of bacterial, archaeal, and eukaryotic adenylate kinase family members in TIGR01351.


Pssm-ID: 130427 [Multi-domain]  Cd Length: 188  Bit Score: 148.81  E-value: 4.60e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5G3Y_A          5 LLGPPGAGKGTQAEKIVEEYGIPHISTGDMFRAAIKEGTELGLKAKEYMDKGELVPDEVTIGLVKER-LSQPDCKKGFLL 83
Cdd:TIGR01360   8 IVGGPGSGKGTQCEKIVEKYGFTHLSTGDLLRAEVASGSERGKQLQAIMESGDLVPLDTVLDLLKDAmVAALGTSKGFLI 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5G3Y_A         84 DGFPRTVAQAEALDKILKElgikLDAVINIEVPREELLERLTGRrvcrqcgatyhvifnppkvegvcdkcgGELYQRSDD 163
Cdd:TIGR01360  88 DGYPREVKQGEEFERRIGP----PTLVLYFDCSEDTMVKRLLKR---------------------------AETSGRVDD 136

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
5G3Y_A        164 NEETVSNRLDVYEDQTAPLIDYYEKKGLLKNIDGDQDIDAVFADIKAAL 212
Cdd:TIGR01360 137 NEKTIKKRLETYYKATEPVIAYYETKGKLRKINAEGTVDDVFLQVCTAI 185
AAA_17 pfam13207
AAA domain;
6-128 1.98e-41

AAA domain;


Pssm-ID: 463810 [Multi-domain]  Cd Length: 136  Bit Score: 137.76  E-value: 1.98e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5G3Y_A          6 LGPPGAGKGTQAEKIVEEYGIPHISTGDMFRAAIKEGTelGLKAKEYMDKGELVPDEVTIGLVKERLSQPDCKKGFLLDG 85
Cdd:pfam13207   1 TGVPGSGKTTQLKKLAEKLGFPHISAGDLLREEAKERG--LVEDRDEMRKLPLEPQKELQKLAAERIAEEAGEGGVIVDG 78

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
5G3Y_A         86 FPRTVAQAEALDKILKELG--IKLDAVINIEVPREELLERLTGRR 128
Cdd:pfam13207  79 HPRIKTPAGYLPGLPVEVLreLKPDAIILLEADPEEILERRLKDR 123
PLN02200 PLN02200
adenylate kinase family protein
 5-209 1.37e-33

adenylate kinase family protein


Pssm-ID: 215125 [Multi-domain]  Cd Length: 234  Bit Score: 120.38  E-value: 1.37e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5G3Y_A         5 LLGPPGAGKGTQAEKIVEEYGIPHISTGDMFRAAIKEGTELGLKAKEYMDKGELVPDEVTIGLVKERLSQPDCKKgFLLD 84
Cdd:PLN02200  48 VLGGPGSGKGTQCEKIVETFGFKHLSAGDLLRREIASNSEHGAMILNTIKEGKIVPSEVTVKLIQKEMESSDNNK-FLID 126

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5G3Y_A        85 GFPRTVAQAEALDKILkelGIKLDAVINIEVPREELLERLTGRRvcrqcgatyhvifnppkvEGvcdkcggelyqRSDDN 164
Cdd:PLN02200 127 GFPRTEENRIAFERII---GAEPNVVLFFDCPEEEMVKRVLNRN------------------QG-----------RVDDN 174

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
5G3Y_A       165 EETVSNRLDVYEDQTAPLIDYYEKKGLLKNIDGDQDIDAVFADIK 209
Cdd:PLN02200 175 IDTIKKRLKVFNALNLPVIDYYSKKGKLYTINAVGTVDEIFEQVR 219
ADK_lid pfam05191
Adenylate kinase, active site lid; Comparisons of adenylate kinases have revealed a particular ...
 127-162 3.02e-22

Adenylate kinase, active site lid; Comparisons of adenylate kinases have revealed a particular divergence in the active site lid. In some organizms, particularly the Gram-positive bacteria, residues in the lid domain have been mutated to cysteines and these cysteine residues are responsible for the binding of a zinc ion. The bound zinc ion in the lid domain, is clearly structurally homologous to Zinc-finger domains. However, it is unclear whether the adenylate kinase lid is a novel zinc-finger DNA/RNA binding domain, or that the lid bound zinc serves a purely structural function.


Pssm-ID: 461578 [Multi-domain]  Cd Length: 36  Bit Score: 85.21  E-value: 3.02e-22
                          10        20        30
                  ....*....|....*....|....*....|....*.
5G3Y_A        127 RRVCRQCGATYHVIFNPPKVEGVCDKCGGELYQRSD 162
Cdd:pfam05191   1 RRVCPKCGRIYHVYFNPPKVEGVCDVCGGELVQRDD 36
AAA_33 pfam13671
AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the ...
 3-127 6.26e-08

AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the AAA superfamily. Many of the proteins in this family are just short fragments so there is no Walker B motif.


Pssm-ID: 463952 [Multi-domain]  Cd Length: 143  Bit Score: 50.00  E-value: 6.26e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5G3Y_A          3 LILL-GPPGAGKGTQAEKIVEEYGIPHISTgDMFRAAIKEgtELGLKAKEYMDKGELVPdEVTIGLVKERLSQpdcKKGF 81
Cdd:pfam13671   1 LILLvGLPGSGKSTLARRLLEELGAVRLSS-DDERKRLFG--EGRPSISYYTDATDRTY-ERLHELARIALRA---GRPV 73

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
5G3Y_A         82 LLDGFPRTVAQAEALDKILKELGIKLDAVInIEVPREELLERLTGR 127
Cdd:pfam13671  74 ILDATNLRRDERARLLALAREYGVPVRIVV-FEAPEEVLRERLAAR 118
cyt_kin_arch TIGR02173
cytidylate kinase, putative; Proteins in this family are believed to be cytidylate kinase. ...
 1-61 1.44e-07

cytidylate kinase, putative; Proteins in this family are believed to be cytidylate kinase. Members of this family are found in the archaea and in spirochaetes, and differ considerably from the common bacterial form of cytidylate kinase described by TIGR00017.


Pssm-ID: 274012 [Multi-domain]  Cd Length: 171  Bit Score: 49.73  E-value: 1.44e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
5G3Y_A          1 MNLILLGPPGAGKGTQAEKIVEEYGIPHISTGDMFRAAIKegtELGLKAKEYMDKGELVPD 61
Cdd:TIGR02173   1 MIITISGPPGSGKTTVAKILAEKLSLKLISAGDIFRELAA---KMGLDLIEFLNYAEENPE 58
COG0645 COG0645
Predicted kinase, contains AAA domain [General function prediction only];
3-128 5.92e-07

Predicted kinase, contains AAA domain [General function prediction only];


Pssm-ID: 440410 [Multi-domain]  Cd Length: 164  Bit Score: 47.60  E-value: 5.92e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5G3Y_A        3 LILL-GPPGAGKGTQAEKIVEEYGIPHISTgDMFRAAI-KEGTELGLKAKEYMDKGElvpdEVTIGLVKERLSQpdckkG 80
Cdd:COG0645   1 LILVcGLPGSGKSTLARALAERLGAVRLRS-DVVRKRLfGAGLAPLERSPEATARTY----ARLLALARELLAA-----G 70

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|
5G3Y_A       81 F--LLDGFPRTVAQAEALDKILKELGIKLdAVINIEVPREELLERLTGRR 128
Cdd:COG0645  71 RsvILDATFLRRAQREAFRALAEEAGAPF-VLIWLDAPEEVLRERLEARN 119
PRK04182 PRK04182
cytidylate kinase; Provisional
 7-36 1.74e-06

cytidylate kinase; Provisional


Pssm-ID: 235244 [Multi-domain]  Cd Length: 180  Bit Score: 46.72  E-value: 1.74e-06
                         10        20        30
                 ....*....|....*....|....*....|
5G3Y_A         7 GPPGAGKGTQAEKIVEEYGIPHISTGDMFR 36
Cdd:PRK04182   7 GPPGSGKTTVARLLAEKLGLKHVSAGEIFR 36
PRK01184 PRK01184
flagellar hook-basal body complex protein FliE;
1-127 9.08e-06

flagellar hook-basal body complex protein FliE;


Pssm-ID: 234914 [Multi-domain]  Cd Length: 184  Bit Score: 44.55  E-value: 9.08e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5G3Y_A         1 MNLILL-GPPGAGKGtQAEKIVEEYGIPHISTGDMFRAAIKE-GTEL---GLKAKEYMDKGELVPDEV---TIGLVKERL 72
Cdd:PRK01184   1 MKIIGVvGMPGSGKG-EFSKIAREMGIPVVVMGDVIREEVKKrGLEPtdeNIGKVAIDLRKELGMDAVakrTVPKIREKG 79

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
5G3Y_A        73 SqpdckKGFLLDGFpRTVAQAEALDKILKElGIKLdavINIEVPREELLERLTGR 127
Cdd:PRK01184  80 D-----EVVVIDGV-RGDAEVEYFRKEFPE-DFIL---IAIHAPPEVRFERLKKR 124
CMPK cd02020
Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine ...
 7-34 4.84e-05

Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor.


Pssm-ID: 238978 [Multi-domain]  Cd Length: 147  Bit Score: 42.09  E-value: 4.84e-05
                        10        20
                ....*....|....*....|....*...
5G3Y_A        7 GPPGAGKGTQAEKIVEEYGIPHISTGDM 34
Cdd:cd02020   6 GPAGSGKSTVAKLLAKKLGLPYLDTGGI 33
COG4639 COG4639
Predicted kinase [General function prediction only];
3-140 3.58e-04

Predicted kinase [General function prediction only];


Pssm-ID: 443677 [Multi-domain]  Cd Length: 145  Bit Score: 39.43  E-value: 3.58e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5G3Y_A        3 LILL-GPPGAGKGTQAEKIVEEYGIphISTgDMFRAaikegtELGLKAKEYMDKGELVpdEVTIGLVKERLSQpdcKKGF 81
Cdd:COG4639   4 LVVLiGLPGSGKSTFARRLFAPTEV--VSS-DDIRA------LLGGDENDQSAWGDVF--QLAHEIARARLRA---GRLT 69

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|..
5G3Y_A       82 LLDGfprTVAQAEA---LDKILKELGIKLDAVInIEVPREELLERLTGRRvcRQCGAtyHVI 140
Cdd:COG4639  70 VVDA---TNLQREArrrLLALARAYGALVVAVV-LDVPLEVCLARNAARD--RQVPE--EVI 123
Cmk COG0283
Cytidylate kinase [Nucleotide transport and metabolism];
7-45 1.85e-03

Cytidylate kinase [Nucleotide transport and metabolism];


Pssm-ID: 440052 [Multi-domain]  Cd Length: 220  Bit Score: 38.08  E-value: 1.85e-03
                        10        20        30        40
                ....*....|....*....|....*....|....*....|...
5G3Y_A        7 GPPGAGKGTQAEKIVEEYGIPHISTGDMFRA----AIKEGTEL 45
Cdd:COG0283   7 GPAGSGKSTVAKALAKRLGYHYLDTGAMYRAvalaALRNGIDL 49
PRK11032 PRK11032
zinc ribbon-containing protein;
126-160 2.94e-03

zinc ribbon-containing protein;


Pssm-ID: 182915  Cd Length: 160  Bit Score: 36.90  E-value: 2.94e-03
                         10        20        30
                 ....*....|....*....|....*....|....*
5G3Y_A       126 GRRVCRQCGatYHVIFNPPKVEGVCDKCGGELYQR 160
Cdd:PRK11032 123 GNLVCEKCH--HHLAFYTPEVLPLCPKCGHDQFQR 155
cmk TIGR00017
cytidylate kinase; This family consists of cytidylate kinase, which catalyzes the ...
 1-37 3.69e-03

cytidylate kinase; This family consists of cytidylate kinase, which catalyzes the phosphorylation of cytidine 5-monophosphate (dCMP) to cytidine 5 -diphosphate (dCDP) in the presence of ATP or GTP. UMP and dCMP can also act as acceptors. [Purines, pyrimidines, nucleosides, and nucleotides, Nucleotide and nucleoside interconversions]


Pssm-ID: 129128 [Multi-domain]  Cd Length: 217  Bit Score: 37.41  E-value: 3.69e-03
                          10        20        30
                  ....*....|....*....|....*....|....*....
5G3Y_A          1 MNLILL--GPPGAGKGTQAEKIVEEYGIPHISTGDMFRA 37
Cdd:TIGR00017   1 MAMIIAidGPSGAGKSTVAKAVAEKLGYAYLDSGAMYRA 39
Cytidylate_kin pfam02224
Cytidylate kinase; Cytidylate kinase EC:2.7.4.14 catalyzes the phosphorylation of cytidine 5 ...
 7-37 7.54e-03

Cytidylate kinase; Cytidylate kinase EC:2.7.4.14 catalyzes the phosphorylation of cytidine 5'-monophosphate (dCMP) to cytidine 5'-diphosphate (dCDP) in the presence of ATP or GTP.


Pssm-ID: 280401 [Multi-domain]  Cd Length: 211  Bit Score: 36.51  E-value: 7.54e-03
                          10        20        30
                  ....*....|....*....|....*....|.
5G3Y_A          7 GPPGAGKGTQAEKIVEEYGIPHISTGDMFRA 37
Cdd:pfam02224   5 GPSGSGKSTVARILARKLGYKYLDTGAMYRA 35
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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