|
Name |
Accession |
Description |
Interval |
E-value |
| MCM |
smart00350 |
minichromosome maintenance proteins; |
272-836 |
0e+00 |
|
minichromosome maintenance proteins;
Pssm-ID: 214631 [Multi-domain] Cd Length: 509 Bit Score: 809.57 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 272 TVHRIRDIRSEKIGSLLSISGTVTRTSEVRPELYKASFTCDMCRAIVDNVEQSFKYTEPTFCPNPSCENRAFWTLNVTRS 351
Cdd:smart00350 1 KPSSIRELRADHLGKLVRISGIVTRTSGVRPKLKRASFTCEKCGATLGPEIQSGRETEPTVCPPRECQSPTPFSLNHERS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 352 RFLDWQKVRIQENANEIPTGSMPRTLDVILRGDSVERAKPGDRCKFTGVEIVVPdvTQLGLPGVKpsstldtrgisktte 431
Cdd:smart00350 81 TFIDFQKIKLQESPEEVPVGQLPRSVDVILDGDLVDKAKPGDRVEVTGIYRNVP--YGFKLNTVK--------------- 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 432 GLNSGVTGLRSLGVRDLTYKISFLACHVIsigsnigasspdansnnretelqmaanlqannvyqdnerdqevfLNSLSSD 511
Cdd:smart00350 144 GLPVFATYIEANHVRKLDYKRSFEDSSFS--------------------------------------------VQSLSDE 179
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 512 EINELKEMVKDEHIYDKLVRSIAPAVFGHEAVKKGILLQMLGGVHKSTVEGIKLRGDINICVVGDPSTSKSQFLKYVVGF 591
Cdd:smart00350 180 EEEEIRKLSKDPDIYERLARSLAPSIYGHEDIKKAILLLLFGGVHKNLPDGMKIRGDINILLCGDPGTAKSQLLKYVEKT 259
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 592 APRSVYTSGKASSAAGLTAAVVRDEEGGDYTIEAGALMLADNGICCIDEFDKMDISDQVAIHEAMEQQTISIAKAGIHAT 671
Cdd:smart00350 260 APRAVYTTGKGSSAVGLTAAVTRDPETREFTLEAGALVLADNGVCCIDEFDKMDDSDRTAIHEAMEQQTISIAKAGITTT 339
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 672 LNARTSILAAANPVGGRYNRKLSLRGNLNMTAPIMSRFDLFFVILDDCNEKIDTELASHIVDLHMKR----DEAIEPPFS 747
Cdd:smart00350 340 LNARCSVLAAANPIGGRYDPKLTPEENIDLPAPILSRFDLLFVVLDEVDEERDRELAKHVVDLHRYShpeeDEAFEPPLS 419
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 748 AEQLRRYIKYART-FKPILTKEARSYLVEKYKELRKDDAQGFSRSSYRITVRQLESMIRLSEAIARANCVDEITPSFIAE 826
Cdd:smart00350 420 QEKLRKYIAYAREkIKPKLSEEAADKLVKAYVDLRKEDSQTESRSSIPITVRQLESIIRLSEAHAKMRLSDVVEEADVEE 499
|
570
....*....|
6PTN_m 827 AYDLLRQSII 836
Cdd:smart00350 500 AIRLLRESII 509
|
|
| MCM6 |
cd17757 |
DNA replication licensing factor Mcm6; Mcm6 is a helicase that play an important role in ... |
528-834 |
0e+00 |
|
DNA replication licensing factor Mcm6; Mcm6 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350663 [Multi-domain] Cd Length: 307 Bit Score: 627.47 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 528 KLVRSIAPAVFGHEAVKKGILLQMLGGVHKSTVEGIKLRGDINICVVGDPSTSKSQFLKYVVGFAPRSVYTSGKASSAAG 607
Cdd:cd17757 1 NLVRSIAPSIYGHEEVKKGILLMLLGGVHKITREGISLRGDINVCIVGDPSTAKSQFLKYVEEFSPRAVYTSGKASSAAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 608 LTAAVVRDEEGGDYTIEAGALMLADNGICCIDEFDKMDISDQVAIHEAMEQQTISIAKAGIHATLNARTSILAAANPVGG 687
Cdd:cd17757 81 LTAAVVRDEETGDFVIEAGALMLADNGICCIDEFDKMDIKDQVAIHEAMEQQTISITKAGIQATLNARTSILAAANPVGG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 688 RYNRKLSLRGNLNMTAPIMSRFDLFFVILDDCNEKIDTELASHIVDLHMKRDEAIEPPFSAEQLRRYIKYARTFKPILTK 767
Cdd:cd17757 161 RYDRSKSLKQNINISAPIMSRFDLFFVLLDECNEVTDYAIASHIVDLHSKREEAIEPPFTAEQLKRYIAYARTFKPKLTK 240
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
6PTN_m 768 EARSYLVEKYKELRKDDAQGFSRSSYRITVRQLESMIRLSEAIARANCVDEITPSFIAEAYDLLRQS 834
Cdd:cd17757 241 EAKDELVEQYKELRQDDASGSTRSSYRITVRQLESLIRLSEAIARLHCSDEVTPEHVEEAARLLKKS 307
|
|
| Mcm2 |
COG1241 |
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and ... |
267-820 |
0e+00 |
|
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair];
Pssm-ID: 440854 [Multi-domain] Cd Length: 682 Bit Score: 555.95 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 267 FFNLPTVHRIRDIRSEKIGSLLSISGTVTRTSEVRPELYKASFTCDMCRAIVDNVEQSFKYTEPTFCPNpsCENRAFWTL 346
Cdd:COG1241 87 ITNLPETVPIRDIRSDHIGKLISVEGIVRKATEVKPKITEAAFECPRCGTETYVPQTGEKLQEPHECPG--CGRQGPFKL 164
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 347 NVTRSRFLDWQKVRIQENANEIPTGSMPRTLDVILRGDSVERAKPGDRCKFTGVeivvpdvtqlglpgvkpsstldtrgi 426
Cdd:COG1241 165 LPEKSEFIDAQKIRIQEPPEDLPGGQQPQSIDVILEDDLVGEVRPGDRVTVTGI-------------------------- 218
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 427 sktteglnsgvtgLRSLgvrdltykisflachvisigsnigassPDANSNNRETELQMAanLQANNVYQDNERDQEVfln 506
Cdd:COG1241 219 -------------LRIE---------------------------QRTSGRGKSTIFDLY--LEANSIEVEEKEFEEI--- 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 507 SLSSDEINELKEMVKDEHIYDKLVRSIAPAVFGHEAVKKGILLQMLGGVHKSTVEGIKLRGDINICVVGDPSTSKSQFLK 586
Cdd:COG1241 254 EITEEDEEKIKELSKDPDIYEKIIASIAPSIYGYEEIKEAIALQLFGGVPKVLPDGSRIRGDIHILLVGDPGTAKSQLLR 333
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 587 YVVGFAPRSVYTSGKASSAAGLTAAVVRDEEG-GDYTIEAGALMLADNGICCIDEFDKMDISDQVAIHEAMEQQTISIAK 665
Cdd:COG1241 334 YAARLAPRGVYTSGKGSTAAGLTAAAVRDDFGtGRWTLEAGALVLADGGLACIDELDKMREEDRSALHEAMEQQTISIAK 413
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 666 AGIHATLNARTSILAAANPVGGRYNRKLSLRGNLNMTAPIMSRFDLFFVILDDCNEKIDTELASHIVDLHMKRD------ 739
Cdd:COG1241 414 AGIVATLNARCSVLAAANPKYGRFDPYEPIAEQIDLPPTLLSRFDLIFVLRDKPDEERDRELARHILKVHRAGElleqei 493
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 740 ----EAIEPPFSAEQLRRYIKYAR-TFKPILTKEARSYLVEKYKELRKDDAQGfsRSSYRITVRQLESMIRLSEAIARAN 814
Cdd:COG1241 494 eeetEEVKPEIDPDLLRKYIAYARrNVFPVLTEEAKDLIEDFYVDMRKKGEDE--DSPVPITARQLEALIRLAEASARMR 571
|
....*.
6PTN_m 815 CVDEIT 820
Cdd:COG1241 572 LSDTVT 577
|
|
| minchrom_main_MCM |
NF040949 |
minichromosome maintenance protein MCM; |
111-820 |
3.92e-174 |
|
minichromosome maintenance protein MCM;
Pssm-ID: 468880 [Multi-domain] Cd Length: 681 Bit Score: 524.10 E-value: 3.92e-174
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 111 VREAFEQFLEDFsvqsTDTGEVEKvYRAQIEFMKIYDLNTIYIDYQHLSMReNGALAMAISEQYYRFLPFLQKGLRRVVR 190
Cdd:NF040949 1 LGEKFKEFIRTF----RDSFGNEK-YKERIFEMIAMRKRSLVVDFNDLYMF-DPELADLLIEKPDEVLPAASKALKEIVE 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 191 KYAPELlntsdslkrsegdegqadedeqqdddmngsslprdsgssaapgngtsamatrsittstspEQTERVFQISFFNL 270
Cdd:NF040949 75 EEDPEY------------------------------------------------------------AEEVAKFHVRFRNL 94
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 271 PTVHRIRDIRSEKIGSLLSISGTVTRTSEVRPELYKASFTCDMCRAIVDNVEQSFKYTE----PTFCPNpsC-ENRAFwT 345
Cdd:NF040949 95 PRTVPLRDLRSEYIGKLIAVEGIVTRTTPVKPRIVKAVFRCRDCGCEFEWPEEEEESYEivepPTVCPV--CgKPGSF-R 171
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 346 LNVTRSRFLDWQKVRIQENANEIPTGSMPRTLDVILRGDSVERAKPGDRCKFTGVEIVVPDvtqlglpgvkpsstldtrg 425
Cdd:NF040949 172 LLQEKSKFIDWQKIVVQERPEELPPGQLPRSIEVVLEDDLVDTARPGDRVTVTGILRIKPD------------------- 232
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 426 iskttEGLNSGVTGLRSLgvrdltYkisflachvisigsnigasspdansnnretelqmaanLQANNVyqdnERDQEVFL 505
Cdd:NF040949 233 -----SSLKKGSRPIFKN------Y-------------------------------------IEANHI----EVSQKELE 260
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 506 N-SLSSDEINELKEMVKDEHIYDKLVRSIAPAVFGHEAVKKGILLQMLGGVHKSTVEGIKLRGDINICVVGDPSTSKSQF 584
Cdd:NF040949 261 EvEITEEDEEKILELAKDPWIREKIIASIAPSIYGHWEIKEAIALLLFGGVPKVLPDGTRIRGDIHVLIVGDPGTAKSQL 340
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 585 LKYVVGFAPRSVYTSGKASSAAGLTAAVVRDEEGGDYTIEAGALMLADNGICCIDEFDKMDISDQVAIHEAMEQQTISIA 664
Cdd:NF040949 341 LQYVARLAPRAVYTSGKGSTAAGLTAAVVRDKLTGEYYLEAGALVLADGGVAVIDEIDKMREEDRSAIHEAMEQQTVSIA 420
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 665 KAGIHATLNARTSILAAANPVGGRYNRKLSLRGNLNMTAPIMSRFDLFFVILDDCNEKIDTELASHIVDLHmKRDEAIEP 744
Cdd:NF040949 421 KAGIVATLNARASVLAAGNPKFGRYDPNRSVAENIDLPPTILSRFDLIFVIRDKPNEERDRRLARHILDVH-SGKEKVKP 499
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
6PTN_m 745 PFSAEQLRRYIKYARTF-KPILTKEARSYLVEKYKELRKDD-AQGFSRSSYRITVRQLESMIRLSEAIARANCVDEIT 820
Cdd:NF040949 500 EIDPDLLKKYIAYARKYvRPKLTEEAKKLIEDFYVEMRKSSkSSEDPDSPIPITARQLEALIRLSEAHAKMRLKDEVT 577
|
|
| MCM |
pfam00493 |
MCM P-loop domain; |
512-735 |
1.32e-143 |
|
MCM P-loop domain;
Pssm-ID: 459830 [Multi-domain] Cd Length: 224 Bit Score: 427.72 E-value: 1.32e-143
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 512 EINELKEMVKDEHIYDKLVRSIAPAVFGHEAVKKGILLQMLGGVHKSTVEGIKLRGDINICVVGDPSTSKSQFLKYVVGF 591
Cdd:pfam00493 1 DEEEIKELAKRPDIYDKLADSIAPSIYGHEDVKKAILLQLFGGVKKILPDGTRLRGDINVLLVGDPGTAKSQLLKYVEKI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 592 APRSVYTSGKASSAAGLTAAVVRDEEGGDYTIEAGALMLADNGICCIDEFDKMDISDQVAIHEAMEQQTISIAKAGIHAT 671
Cdd:pfam00493 81 APRAVYTSGKGSSAAGLTAAVVRDPVTGEFVLEAGALVLADGGVCCIDEFDKMNDEDRVALHEAMEQQTISIAKAGIVAT 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
6PTN_m 672 LNARTSILAAANPVGGRYNRKLSLRGNLNMTAPIMSRFDLFFVILDDCNEKIDTELASHIVDLH 735
Cdd:pfam00493 161 LNARCSILAAANPIFGRYDPKKSIAENINLPPPLLSRFDLIFVLLDKPDEEKDERLAKHIVDLH 224
|
|
| PTZ00111 |
PTZ00111 |
DNA replication licensing factor MCM4; Provisional |
254-852 |
2.16e-81 |
|
DNA replication licensing factor MCM4; Provisional
Pssm-ID: 173403 [Multi-domain] Cd Length: 915 Bit Score: 284.19 E-value: 2.16e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 254 TSPEQTERVFQISFFNLPTVHRIRDIRSEKIGSLLSISGTVTRTSEVRPELYKASFTCDMCRAI-VDNVE----QSFKYT 328
Cdd:PTZ00111 196 LSLENNSFFPRARLMNKPVSDCVGNLEPSMADSLVQFSGTVVRQTWIVPEITMACFRCRGQKKIgLNDYQpctcEHYEYV 275
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 329 ------EPTFCPNpsCENRAFWTLNVTRSRFLDWQKVRIQENANEIPTGSMPRTldvilrGDSVERAKPGDRCKFTGVEI 402
Cdd:PTZ00111 276 iqgevnEPLLCNE--CNSKYTFELNHNMCVYSTKKIVKLLQSNSSLNNPDKDGL------DNSVDNSGLNGEIYMKDNEV 347
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 403 VVPDVTQLGLPGVKPSSTLDTRGISKTTE-GLNSGVTGLRSLgvrdLTYKISFLACHVIsigsnigasspdaNSNNrete 481
Cdd:PTZ00111 348 INLNLYDDLIDSVKTGDRVTVVGILKVTPiRTSTTRRTLKSL----YTYFVNVIHVKVI-------------NSTN---- 406
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 482 lqmAANLQANNVYQDNErdqevflNSLSSDEINELKEMVKDEHIYDKLVRSIAPAVFGHEAVKKGILLQMLGG------- 554
Cdd:PTZ00111 407 ---ANQPEKGLKYLGNE-------NDFSDLQVYKILELSRNPMIYRILLDSFAPSIKARNNVKIGLLCQLFSGnknssdf 476
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 555 --VHKSTVEGIKLRGDINICVVGDPSTSKSQFLKYVVGFAPRSVYTSGKASSAAGLTAAV-VRDEEGGDYTIEAGALMLA 631
Cdd:PTZ00111 477 nkSPDACYKVDNFRGIINVLLCGDPGTAKSQLLHYTHLLSPRSIYTSGKSSSSVGLTASIkFNESDNGRAMIQPGAVVLA 556
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 632 DNGICCIDEFDKMDISDQVAIHEAMEQQTISIAKAGIHATLNARTSILAAANPVGGRYNRKLSLRGNLNMTAPIMSRFDL 711
Cdd:PTZ00111 557 NGGVCCIDELDKCHNESRLSLYEVMEQQTVTIAKAGIVATLKAETAILASCNPINSRYNKNKAVIENINISPSLFTRFDL 636
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 712 FFVILDDCNEKIDTELASHIV---------------DLHMKR------DEAIEPPFS-----AEQLRRYIKYAR-TFKPI 764
Cdd:PTZ00111 637 IYLVLDHIDQDTDQLISLSIAkdfllphmtgsgndeDTYDRSntmhveDESLRSEKDynkndLDMLRMYIKFSKlHCFPK 716
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 765 LTKEARSYLVEKYKELRK-------------------DDAQGFSRSSYRITV--RQLESMIRLSEAIARANCVDEITPSF 823
Cdd:PTZ00111 717 LSDEAKKVITREYVKMRQgnfqtsnldelehaqedddDDLYYQSSGTRMIYVssRMISSIIRISVSLARMRLSTVVTPAD 796
|
650 660
....*....|....*....|....*....
6PTN_m 824 IAEAYDLLRQSIIRVDVDDVEMDEEFDNI 852
Cdd:PTZ00111 797 ALQAVQIVKSSTFQSLVDPTTGKIDFDQL 825
|
|
| MCM6_C |
pfam18263 |
MCM6 C-terminal winged-helix domain; The minichromosome maintenance (Mcm) complex is the ... |
900-1007 |
3.29e-37 |
|
MCM6 C-terminal winged-helix domain; The minichromosome maintenance (Mcm) complex is the replicative helicase in eukaryotic species, that plays essential roles in the initiation and elongation phases of DNA replication. During late M and early G(1), the Mcm complex is loaded onto chromatin to form prereplicative complex in a Cdt1-dependent manner. This entry represents the C-terminal domain of human Mcm6 which is the Cdt1 binding domain (CBD). The structure of CBD exhibits a typical winged helix fold that is generally involved in protein-nucleic acid interaction. The CBD failed to interact with DNA in experiments. The CBD-Cdt1 interaction involves the helix-turn-helix motif of CBD.
Pssm-ID: 465688 Cd Length: 107 Bit Score: 135.02 E-value: 3.29e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 900 KKTTVTYDKYVSMMNMIVRKIAEVDREGAEELTAVDIVDWYLLQKENDLGSLAEYWEERRLAFKVIKRLVKDRILMEIHG 979
Cdd:pfam18263 1 KKLRITYDKYVKIMNLLVLHLREVEEEEGEGVDRSELIQWYLEQIEDEIESEEELEEEKELVEKVIKRLIKDNILLEIRG 80
|
90 100
....*....|....*....|....*...
6PTN_m 980 TRhNLRDLENEENENNKTVYVIHPNCEV 1007
Cdd:pfam18263 81 EG-LEDEGEEDAEEEEDPVLVVHPNYDI 107
|
|
| MCM_N |
pfam14551 |
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins. |
112-195 |
4.36e-19 |
|
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins.
Pssm-ID: 464206 [Multi-domain] Cd Length: 95 Bit Score: 83.11 E-value: 4.36e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 112 REAFEQFLEDFSVQSTDtgevEKVYRAQIEFMKIYDLNTIYIDYQHLSMRENGaLAMAISEQYYRFLPFLQKGLRRVVRK 191
Cdd:pfam14551 1 KRKFKDFLEEFREDGDG----EFKYRDQLREMIEREQRSLEVDLDDLREFDPD-LAEALLENPYEYLPLFEEALKEVVKE 75
|
....
6PTN_m 192 YAPE 195
Cdd:pfam14551 76 LSED 79
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MCM |
smart00350 |
minichromosome maintenance proteins; |
272-836 |
0e+00 |
|
minichromosome maintenance proteins;
Pssm-ID: 214631 [Multi-domain] Cd Length: 509 Bit Score: 809.57 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 272 TVHRIRDIRSEKIGSLLSISGTVTRTSEVRPELYKASFTCDMCRAIVDNVEQSFKYTEPTFCPNPSCENRAFWTLNVTRS 351
Cdd:smart00350 1 KPSSIRELRADHLGKLVRISGIVTRTSGVRPKLKRASFTCEKCGATLGPEIQSGRETEPTVCPPRECQSPTPFSLNHERS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 352 RFLDWQKVRIQENANEIPTGSMPRTLDVILRGDSVERAKPGDRCKFTGVEIVVPdvTQLGLPGVKpsstldtrgisktte 431
Cdd:smart00350 81 TFIDFQKIKLQESPEEVPVGQLPRSVDVILDGDLVDKAKPGDRVEVTGIYRNVP--YGFKLNTVK--------------- 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 432 GLNSGVTGLRSLGVRDLTYKISFLACHVIsigsnigasspdansnnretelqmaanlqannvyqdnerdqevfLNSLSSD 511
Cdd:smart00350 144 GLPVFATYIEANHVRKLDYKRSFEDSSFS--------------------------------------------VQSLSDE 179
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 512 EINELKEMVKDEHIYDKLVRSIAPAVFGHEAVKKGILLQMLGGVHKSTVEGIKLRGDINICVVGDPSTSKSQFLKYVVGF 591
Cdd:smart00350 180 EEEEIRKLSKDPDIYERLARSLAPSIYGHEDIKKAILLLLFGGVHKNLPDGMKIRGDINILLCGDPGTAKSQLLKYVEKT 259
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 592 APRSVYTSGKASSAAGLTAAVVRDEEGGDYTIEAGALMLADNGICCIDEFDKMDISDQVAIHEAMEQQTISIAKAGIHAT 671
Cdd:smart00350 260 APRAVYTTGKGSSAVGLTAAVTRDPETREFTLEAGALVLADNGVCCIDEFDKMDDSDRTAIHEAMEQQTISIAKAGITTT 339
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 672 LNARTSILAAANPVGGRYNRKLSLRGNLNMTAPIMSRFDLFFVILDDCNEKIDTELASHIVDLHMKR----DEAIEPPFS 747
Cdd:smart00350 340 LNARCSVLAAANPIGGRYDPKLTPEENIDLPAPILSRFDLLFVVLDEVDEERDRELAKHVVDLHRYShpeeDEAFEPPLS 419
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 748 AEQLRRYIKYART-FKPILTKEARSYLVEKYKELRKDDAQGFSRSSYRITVRQLESMIRLSEAIARANCVDEITPSFIAE 826
Cdd:smart00350 420 QEKLRKYIAYAREkIKPKLSEEAADKLVKAYVDLRKEDSQTESRSSIPITVRQLESIIRLSEAHAKMRLSDVVEEADVEE 499
|
570
....*....|
6PTN_m 827 AYDLLRQSII 836
Cdd:smart00350 500 AIRLLRESII 509
|
|
| MCM6 |
cd17757 |
DNA replication licensing factor Mcm6; Mcm6 is a helicase that play an important role in ... |
528-834 |
0e+00 |
|
DNA replication licensing factor Mcm6; Mcm6 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350663 [Multi-domain] Cd Length: 307 Bit Score: 627.47 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 528 KLVRSIAPAVFGHEAVKKGILLQMLGGVHKSTVEGIKLRGDINICVVGDPSTSKSQFLKYVVGFAPRSVYTSGKASSAAG 607
Cdd:cd17757 1 NLVRSIAPSIYGHEEVKKGILLMLLGGVHKITREGISLRGDINVCIVGDPSTAKSQFLKYVEEFSPRAVYTSGKASSAAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 608 LTAAVVRDEEGGDYTIEAGALMLADNGICCIDEFDKMDISDQVAIHEAMEQQTISIAKAGIHATLNARTSILAAANPVGG 687
Cdd:cd17757 81 LTAAVVRDEETGDFVIEAGALMLADNGICCIDEFDKMDIKDQVAIHEAMEQQTISITKAGIQATLNARTSILAAANPVGG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 688 RYNRKLSLRGNLNMTAPIMSRFDLFFVILDDCNEKIDTELASHIVDLHMKRDEAIEPPFSAEQLRRYIKYARTFKPILTK 767
Cdd:cd17757 161 RYDRSKSLKQNINISAPIMSRFDLFFVLLDECNEVTDYAIASHIVDLHSKREEAIEPPFTAEQLKRYIAYARTFKPKLTK 240
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
6PTN_m 768 EARSYLVEKYKELRKDDAQGFSRSSYRITVRQLESMIRLSEAIARANCVDEITPSFIAEAYDLLRQS 834
Cdd:cd17757 241 EAKDELVEQYKELRQDDASGSTRSSYRITVRQLESLIRLSEAIARLHCSDEVTPEHVEEAARLLKKS 307
|
|
| Mcm2 |
COG1241 |
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and ... |
267-820 |
0e+00 |
|
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair];
Pssm-ID: 440854 [Multi-domain] Cd Length: 682 Bit Score: 555.95 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 267 FFNLPTVHRIRDIRSEKIGSLLSISGTVTRTSEVRPELYKASFTCDMCRAIVDNVEQSFKYTEPTFCPNpsCENRAFWTL 346
Cdd:COG1241 87 ITNLPETVPIRDIRSDHIGKLISVEGIVRKATEVKPKITEAAFECPRCGTETYVPQTGEKLQEPHECPG--CGRQGPFKL 164
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 347 NVTRSRFLDWQKVRIQENANEIPTGSMPRTLDVILRGDSVERAKPGDRCKFTGVeivvpdvtqlglpgvkpsstldtrgi 426
Cdd:COG1241 165 LPEKSEFIDAQKIRIQEPPEDLPGGQQPQSIDVILEDDLVGEVRPGDRVTVTGI-------------------------- 218
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 427 sktteglnsgvtgLRSLgvrdltykisflachvisigsnigassPDANSNNRETELQMAanLQANNVYQDNERDQEVfln 506
Cdd:COG1241 219 -------------LRIE---------------------------QRTSGRGKSTIFDLY--LEANSIEVEEKEFEEI--- 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 507 SLSSDEINELKEMVKDEHIYDKLVRSIAPAVFGHEAVKKGILLQMLGGVHKSTVEGIKLRGDINICVVGDPSTSKSQFLK 586
Cdd:COG1241 254 EITEEDEEKIKELSKDPDIYEKIIASIAPSIYGYEEIKEAIALQLFGGVPKVLPDGSRIRGDIHILLVGDPGTAKSQLLR 333
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 587 YVVGFAPRSVYTSGKASSAAGLTAAVVRDEEG-GDYTIEAGALMLADNGICCIDEFDKMDISDQVAIHEAMEQQTISIAK 665
Cdd:COG1241 334 YAARLAPRGVYTSGKGSTAAGLTAAAVRDDFGtGRWTLEAGALVLADGGLACIDELDKMREEDRSALHEAMEQQTISIAK 413
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 666 AGIHATLNARTSILAAANPVGGRYNRKLSLRGNLNMTAPIMSRFDLFFVILDDCNEKIDTELASHIVDLHMKRD------ 739
Cdd:COG1241 414 AGIVATLNARCSVLAAANPKYGRFDPYEPIAEQIDLPPTLLSRFDLIFVLRDKPDEERDRELARHILKVHRAGElleqei 493
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 740 ----EAIEPPFSAEQLRRYIKYAR-TFKPILTKEARSYLVEKYKELRKDDAQGfsRSSYRITVRQLESMIRLSEAIARAN 814
Cdd:COG1241 494 eeetEEVKPEIDPDLLRKYIAYARrNVFPVLTEEAKDLIEDFYVDMRKKGEDE--DSPVPITARQLEALIRLAEASARMR 571
|
....*.
6PTN_m 815 CVDEIT 820
Cdd:COG1241 572 LSDTVT 577
|
|
| minchrom_main_MCM |
NF040949 |
minichromosome maintenance protein MCM; |
111-820 |
3.92e-174 |
|
minichromosome maintenance protein MCM;
Pssm-ID: 468880 [Multi-domain] Cd Length: 681 Bit Score: 524.10 E-value: 3.92e-174
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 111 VREAFEQFLEDFsvqsTDTGEVEKvYRAQIEFMKIYDLNTIYIDYQHLSMReNGALAMAISEQYYRFLPFLQKGLRRVVR 190
Cdd:NF040949 1 LGEKFKEFIRTF----RDSFGNEK-YKERIFEMIAMRKRSLVVDFNDLYMF-DPELADLLIEKPDEVLPAASKALKEIVE 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 191 KYAPELlntsdslkrsegdegqadedeqqdddmngsslprdsgssaapgngtsamatrsittstspEQTERVFQISFFNL 270
Cdd:NF040949 75 EEDPEY------------------------------------------------------------AEEVAKFHVRFRNL 94
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 271 PTVHRIRDIRSEKIGSLLSISGTVTRTSEVRPELYKASFTCDMCRAIVDNVEQSFKYTE----PTFCPNpsC-ENRAFwT 345
Cdd:NF040949 95 PRTVPLRDLRSEYIGKLIAVEGIVTRTTPVKPRIVKAVFRCRDCGCEFEWPEEEEESYEivepPTVCPV--CgKPGSF-R 171
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 346 LNVTRSRFLDWQKVRIQENANEIPTGSMPRTLDVILRGDSVERAKPGDRCKFTGVEIVVPDvtqlglpgvkpsstldtrg 425
Cdd:NF040949 172 LLQEKSKFIDWQKIVVQERPEELPPGQLPRSIEVVLEDDLVDTARPGDRVTVTGILRIKPD------------------- 232
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 426 iskttEGLNSGVTGLRSLgvrdltYkisflachvisigsnigasspdansnnretelqmaanLQANNVyqdnERDQEVFL 505
Cdd:NF040949 233 -----SSLKKGSRPIFKN------Y-------------------------------------IEANHI----EVSQKELE 260
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 506 N-SLSSDEINELKEMVKDEHIYDKLVRSIAPAVFGHEAVKKGILLQMLGGVHKSTVEGIKLRGDINICVVGDPSTSKSQF 584
Cdd:NF040949 261 EvEITEEDEEKILELAKDPWIREKIIASIAPSIYGHWEIKEAIALLLFGGVPKVLPDGTRIRGDIHVLIVGDPGTAKSQL 340
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 585 LKYVVGFAPRSVYTSGKASSAAGLTAAVVRDEEGGDYTIEAGALMLADNGICCIDEFDKMDISDQVAIHEAMEQQTISIA 664
Cdd:NF040949 341 LQYVARLAPRAVYTSGKGSTAAGLTAAVVRDKLTGEYYLEAGALVLADGGVAVIDEIDKMREEDRSAIHEAMEQQTVSIA 420
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 665 KAGIHATLNARTSILAAANPVGGRYNRKLSLRGNLNMTAPIMSRFDLFFVILDDCNEKIDTELASHIVDLHmKRDEAIEP 744
Cdd:NF040949 421 KAGIVATLNARASVLAAGNPKFGRYDPNRSVAENIDLPPTILSRFDLIFVIRDKPNEERDRRLARHILDVH-SGKEKVKP 499
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
6PTN_m 745 PFSAEQLRRYIKYARTF-KPILTKEARSYLVEKYKELRKDD-AQGFSRSSYRITVRQLESMIRLSEAIARANCVDEIT 820
Cdd:NF040949 500 EIDPDLLKKYIAYARKYvRPKLTEEAKKLIEDFYVEMRKSSkSSEDPDSPIPITARQLEALIRLSEAHAKMRLKDEVT 577
|
|
| MCM |
cd17706 |
MCM helicase family; MCM helicases are a family of helicases that play an important role in ... |
528-834 |
3.38e-167 |
|
MCM helicase family; MCM helicases are a family of helicases that play an important role in replication and homologous recombination repair. The heterohexameric ring-shaped Mcm2-7 complex is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases. Mcm8 and Mcm9, form a complex required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350658 [Multi-domain] Cd Length: 311 Bit Score: 492.24 E-value: 3.38e-167
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 528 KLVRSIAPAVFGHEAVKKGILLQMLGGVHKSTVEGIKLRGDINICVVGDPSTSKSQFLKYVVGFAPRSVYTSGKASSAAG 607
Cdd:cd17706 1 ILADSIAPSIYGHEDVKKAVLLQLFGGVQKILEDGTRIRGDIHILLVGDPGTAKSQILKYVLKIAPRGVYTSGKGSSGAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 608 LTAAVVRDEEGGDYTIEAGALMLADNGICCIDEFDKMDISDQVAIHEAMEQQTISIAKAGIHATLNARTSILAAANPVGG 687
Cdd:cd17706 81 LTAAVVRDSETGEWYLEAGALVLADGGVCCIDEFDKMKELDRTALHEAMEQQTISIAKAGIVTTLNARCSILAAANPKGG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 688 RYNRKLSLRGNLNMTAPIMSRFDLFFVILDDCNEKIDTELASHIVDLHMKRD-------EAIEPPFSAEQLRRYIKYART 760
Cdd:cd17706 161 RYNPKLSPIENINLPSPLLSRFDLIFVIRDDPDEERDEELAEHIIDLHRGSDpeeqvkpEEDGIPIDIELLRKYILYARQ 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
6PTN_m 761 FKPILTKEARSYLVEKYKELRKDDAQgfsRSSYRITVRQLESMIRLSEAIARANCVDEITPSFIAEAYDLLRQS 834
Cdd:cd17706 241 IHPKISEEAREKLVRWYVELRKESER---RSTIPITARQLESVIRLAEAHAKMRLSEVVTEEDVEEAIRLVRHS 311
|
|
| MCM |
pfam00493 |
MCM P-loop domain; |
512-735 |
1.32e-143 |
|
MCM P-loop domain;
Pssm-ID: 459830 [Multi-domain] Cd Length: 224 Bit Score: 427.72 E-value: 1.32e-143
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 512 EINELKEMVKDEHIYDKLVRSIAPAVFGHEAVKKGILLQMLGGVHKSTVEGIKLRGDINICVVGDPSTSKSQFLKYVVGF 591
Cdd:pfam00493 1 DEEEIKELAKRPDIYDKLADSIAPSIYGHEDVKKAILLQLFGGVKKILPDGTRLRGDINVLLVGDPGTAKSQLLKYVEKI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 592 APRSVYTSGKASSAAGLTAAVVRDEEGGDYTIEAGALMLADNGICCIDEFDKMDISDQVAIHEAMEQQTISIAKAGIHAT 671
Cdd:pfam00493 81 APRAVYTSGKGSSAAGLTAAVVRDPVTGEFVLEAGALVLADGGVCCIDEFDKMNDEDRVALHEAMEQQTISIAKAGIVAT 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
6PTN_m 672 LNARTSILAAANPVGGRYNRKLSLRGNLNMTAPIMSRFDLFFVILDDCNEKIDTELASHIVDLH 735
Cdd:pfam00493 161 LNARCSILAAANPIFGRYDPKKSIAENINLPPPLLSRFDLIFVLLDKPDEEKDERLAKHIVDLH 224
|
|
| MCM7 |
cd17758 |
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in ... |
528-834 |
2.48e-122 |
|
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350664 [Multi-domain] Cd Length: 306 Bit Score: 375.59 E-value: 2.48e-122
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 528 KLVRSIAPAVFGHEAVKKGILLQMLGGVHKStVEGIKLRGDINICVVGDPSTSKSQFLKYVVGFAPRSVYTSGKASSAAG 607
Cdd:cd17758 1 KLAASIAPEIYGHEDVKKALLLLLVGGVDKR-GDGMKIRGDINICLMGDPGVAKSQLLKYICRIAPRSVYTTGRGSSGVG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 608 LTAAVVRDEEGGDYTIEAGALMLADNGICCIDEFDKMDISDQVAIHEAMEQQTISIAKAGIHATLNARTSILAAANPVGG 687
Cdd:cd17758 80 LTAAVMKDPVTGEMTLEGGALVLADQGICCIDEFDKMDESDRTAIHEVMEQQTISIAKAGITTTLNARTSILAAANPAYG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 688 RYNRKLSLRGNLNMTAPIMSRFDLFFVILDDCNEKIDTELASHIVDLHM---KRDEAIEpPFSAEQLRRYIKYARTFKPI 764
Cdd:cd17758 160 RYNPRRSPEQNINLPAALLSRFDLLFLILDKPDRDNDLRLAEHVTYVHQhnkQPDSDFE-PLDPKLLRAYIALAKRKRPT 238
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 765 LTKEARSYLVEKYKELRKDDAQgfSRSSYRITVRQLESMIRLSEAIARANCVDEITPSFIAEAYDLLRQS 834
Cdd:cd17758 239 VPPALADYIVQAYVEMRQEAKR--SKDFTFTTPRTLLAILRLSQALARLRLSDSVEIDDVEEALRLMEMS 306
|
|
| MCM4 |
cd17755 |
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in ... |
528-834 |
1.24e-119 |
|
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350661 [Multi-domain] Cd Length: 309 Bit Score: 368.69 E-value: 1.24e-119
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 528 KLVRSIAPAVFGHEAVKKGILLQMLGGVHKS-TVEGIKLRGDINICVVGDPSTSKSQFLKYVVGFAPRSVYTSGKASSAA 606
Cdd:cd17755 1 RLARSIAPSIYELEDVKKGILLQLFGGTRKDfTKTGGKYRGDINILLCGDPGTSKSQLLQYVHKISPRGVYTSGKGSSAV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 607 GLTAAVVRDEEGGDYTIEAGALMLADNGICCIDEFDKMDISDQVAIHEAMEQQTISIAKAGIHATLNARTSILAAANPVG 686
Cdd:cd17755 81 GLTAYVTRDPDTKQLVLESGALVLSDGGICCIDEFDKMSDSTRSVLHEVMEQQTLSIAKAGIITTLNARTSILASANPIG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 687 GRYNRKLSLRGNLNMTAPIMSRFDLFFVILDDCNEKIDTELASHIVDLHMKRDEAIEPP--FSAEQLRRYIKYAR-TFKP 763
Cdd:cd17755 161 SRYNPKLTVVENIDLPPTLLSRFDLIYLVLDKVDEKYDRRLAKHLVSLYLEDTPEHIQDevLDVEVLTDYISYAReHIHP 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
6PTN_m 764 ILTKEARSYLVEKYKELRKDDAQGFSRSSyrITVRQLESMIRLSEAIARANCVDEITPSFIAEAYDLLRQS 834
Cdd:cd17755 241 KLSEEAAQELVQAYVDMRKMGSDARKRIT--ATPRQLESLIRLAEAHAKMRLSNVVEAEDVEEAVRLIREA 309
|
|
| MCM5 |
cd17756 |
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in ... |
528-834 |
1.43e-119 |
|
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350662 [Multi-domain] Cd Length: 317 Bit Score: 368.63 E-value: 1.43e-119
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 528 KLVRSIAPAVFGHEAVKKGILLQMLGGVHKSTVEGIKLRGDINICVVGDPSTSKSQFLKYVVGFAPRSVYTSGKASSAAG 607
Cdd:cd17756 1 IISKSIAPSIYGNEDIKKAIACLLFGGSRKRLPDGMRLRGDINVLLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 608 LTAAVVRDEEGGDYTIEAGALMLADNGICCIDEFDKMDISDQVAIHEAMEQQTISIAKAGIHATLNARTSILAAANPVGG 687
Cdd:cd17756 81 LTASVMRDPSTREFYLEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRTSVLAAANPVFG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 688 RYNRKLSLRGNLNMTAPIMSRFDLFFVILDDCNEKIDTELASHIVDLHMKRDEA-----IEPPFSAEQLRRYIKYAR-TF 761
Cdd:cd17756 161 RYDDLKTPGDNIDFQTTILSRFDMIFIVKDKHDEERDITIAKHVINIHASARKAsqsqeNEGEIPISKLKRYIAYCRaKC 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
6PTN_m 762 KPILTKEARSYLVEKY----KELRKDDAQGFSRSSYRITVRQLESMIRLSEAIARANCVDEITPSFIAEAYDLLRQS 834
Cdd:cd17756 241 APRLSEEAAEKLSNHYvtirKDVRQNELESDNRSSIPITVRQLEAIIRISESLAKMELSPIATEKHVEEAIRLFQVS 317
|
|
| MCM_arch |
cd17761 |
archaeal MCM protein; archaeal MCM proteins form a homohexameric ring homologous to the ... |
527-821 |
1.40e-118 |
|
archaeal MCM protein; archaeal MCM proteins form a homohexameric ring homologous to the eukaryotic Mcm2-7 helicase and also function as the replicative helicase at the replication fork
Pssm-ID: 350667 [Multi-domain] Cd Length: 308 Bit Score: 366.01 E-value: 1.40e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 527 DKLVRSIAPAVFGHEAVKKGILLQMLGGVHKSTVEGIKLRGDINICVVGDPSTSKSQFLKYVVGFAPRSVYTSGKASSAA 606
Cdd:cd17761 1 EKIISSIAPSIYGHEDVKEAIALQLFGGVPKVLPDGTRIRGDIHILLVGDPGTAKSQLLKYVSKVAPRAVYTTGKGSTAA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 607 GLTAAVVRDEEGGDYTIEAGALMLADNGICCIDEFDKMDISDQVAIHEAMEQQTISIAKAGIHATLNARTSILAAANPVG 686
Cdd:cd17761 81 GLTAAVVRDEGTGEWYLEAGALVLADKGIAVVDEIDKMRKEDRSALHEAMEQQTISIAKAGIVATLNARAAVLAAANPKF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 687 GRYNRKLSLRGNLNMTAPIMSRFDLFFVILDDCNEKIDTELASHIVDLH-MKRDEAIEPPFSAEQLRRYIKYAR-TFKPI 764
Cdd:cd17761 161 GRFDSYRPVAEQIDLPPTLLSRFDLIFVLKDTPNEEKDRRLANHILDTHsGGEMREIKPEIDPDLLRKYIAYARkNVRPV 240
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
6PTN_m 765 LTKEARSYLVEKYKELRKdDAQGfSRSSYRITVRQLESMIRLSEAIARANCVDEITP 821
Cdd:cd17761 241 LTEEAKQLIKDFYVEMRK-SGQE-TPSPVPITARQLEALVRLSEASARMRLSQEVTL 295
|
|
| MCM3 |
cd17754 |
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in ... |
529-832 |
3.66e-108 |
|
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350660 [Multi-domain] Cd Length: 299 Bit Score: 337.90 E-value: 3.66e-108
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 529 LVRSIAPAVFGHEAVKKGILLQMLGGVHKSTVEGIKLRGDINICVVGDPSTSKSQFLKYVVGFAPRSVYTSGKASSAAGL 608
Cdd:cd17754 2 LSKSLAPSIYGHEYIKKAILLMLLGGVEKNLENGSHLRGDINILLVGDPSVAKSQLLRYVLNTAPLAIATTGRGSSGVGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 609 TAAVVRDEEGGDYTIEAGALMLADNGICCIDEFDKMDISDQVAIHEAMEQQTISIAKAGIHATLNARTSILAAANPVGGR 688
Cdd:cd17754 82 TAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRVAIHEVMEQQTVTIAKAGIHASLNARCSVLAAANPVYGR 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 689 YNRKLSLRGNLNMTAPIMSRFDLFFVILDDCNEKIDTELASHIVDLHMkrdeaieppfSAEQLRRYIKYART-FKPILTK 767
Cdd:cd17754 162 YDVYKTPMENIGLPDSLLSRFDLLFIVLDDIDEERDRSISEHVLRMHR----------YIKFLRKYIHYAKErIKPKLTQ 231
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
6PTN_m 768 EARSYLVEKYKELRKDDAQG-FSRSSYRITVRQLESMIRLSEAIARANCVDEITPSFIAEAYDLLR 832
Cdd:cd17754 232 EAAEYIAEEYADLRNDDNTKtDKARTSPITARTLETLIRLATAHAKARLSKTVDKVDAEVALNLLR 297
|
|
| MCM2 |
cd17753 |
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in ... |
528-841 |
9.47e-106 |
|
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350659 [Multi-domain] Cd Length: 325 Bit Score: 332.88 E-value: 9.47e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 528 KLVRSIAPAVFGHEAVKKGILLQMLGGVHKSTVEGIKLRGDINICVVGDPSTSKSQFLKYVVGFAPRSVYTSGKASSAAG 607
Cdd:cd17753 1 RIINSIAPSIYGHDDIKTAIALALFGGVAKNPGGKHRIRGDINVLLLGDPGTAKSQFLKYVEKTAHRAVFTTGQGASAVG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 608 LTAAVVRDEEGGDYTIEAGALMLADNGICCIDEFDKMDISDQVAIHEAMEQQTISIAKAGIHATLNARTSILAAANPVGG 687
Cdd:cd17753 81 LTASVRKDPVTKEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCSVIAAANPIGG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 688 RYNRKLSLRGNLNMTAPIMSRFDLFFVILDDCNEKIDTELASHIVDLHMKRDEAIEP--------------------PFS 747
Cdd:cd17753 161 RYNPTLTFAQNVNLTEPILSRFDILCVVRDTVDPEEDERLAKFVVGSHVRSHPENDEdregeeeknqrqrpketkvePIP 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 748 AEQLRRYIKYART-FKPILTKEARSYLVEKYKELRKddaQGFSRSSYRITVRQLESMIRLSEAIARANCVDEITPSFIAE 826
Cdd:cd17753 241 QELLRKYIHYAREkVRPKLNQMDMDKVSRVYADLRK---ESMATGSLPITVRHLESIIRISEAHAKMHLREYVSEEDVDM 317
|
330
....*....|....*
6PTN_m 827 AydllrqsiIRVDVD 841
Cdd:cd17753 318 A--------IRVMLD 324
|
|
| MCM8 |
cd17759 |
DNA helicase Mcm8; Mcm8 plays an important role homologous recombination repair. It forms a ... |
529-834 |
6.15e-91 |
|
DNA helicase Mcm8; Mcm8 plays an important role homologous recombination repair. It forms a complex with Mcm9 that is required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350665 [Multi-domain] Cd Length: 289 Bit Score: 291.74 E-value: 6.15e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 529 LVRSIAPAVFGHEAVKKGILLQMLGGVHKSTVEG--IKLRGDINICVVGDPSTSKSQFLKYVVGFAPRSVYTSGKASSAA 606
Cdd:cd17759 2 IVNSLCPAIYGHELVKAGLLLSLFGGKQKYADDKnrIPIRGDPHVLIVGDPGLGKSQMLQAACNIAPRGVYVCGNTTTTS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 607 GLTAAVVRDEEGGDYTIEAGALMLADNGICCIDEFDKMDiSDQVAIHEAMEQQTISIAKAGIHATLNARTSILAAANPVG 686
Cdd:cd17759 82 GLTVTLTKDGRSGDFALEAGALVLGDQGICGIDEFDKMG-SQHQALLEAMEQQSVSLAKAGVVCSLPARTSVIAAANPVG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 687 GRYNRKLSLRGNLNMTAPIMSRFDLFFVILDDCNEKIDtelasHIVDLHMkrdeaieppfsaEQLRRYIKYARTF-KPIL 765
Cdd:cd17759 161 GHYNKGKTVSENLKMGPALLSRFDLVFILLDTPSEEHD-----HLLSEHH------------QLLRKYISYARQYvNPVL 223
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
6PTN_m 766 TKEARSYLVEKYKELRKddaQGFSRSSYRITVRQLESMIRLSEAIARANCVDEITPSFIAEAYDLLRQS 834
Cdd:cd17759 224 SKDASEALQEFYLELRK---QNQLADSSPITTRQLESLIRLTEARARLELREEATKEDAEDVIEIMKES 289
|
|
| MCM9 |
cd17760 |
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a ... |
529-820 |
3.62e-84 |
|
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a complex with Mcm8 that is required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350666 [Multi-domain] Cd Length: 299 Bit Score: 274.04 E-value: 3.62e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 529 LVRSIAPAVFGHEAVKKGILLQMLGGVHKSTVEGIKLRGDINICVVGDPSTSKSQFLKYVVGFAPRSVYTSGKASSAAGL 608
Cdd:cd17760 2 ILASLCPQVFGLYNVKLAVAMVLAGGVQRIDASGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTAGIGSTSAGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 609 TAAVVRDeeGGDYTIEAGALMLADNGICCIDEFDKMDISDQVAIHEAMEQQTISIAKAGIHATLNARTSILAAANPvGGR 688
Cdd:cd17760 82 TVTAVKD--GGEWNLEAGALVLADGGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNP-KGQ 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 689 YNRKLSLRGNLNMTAPIMSRFDLFFVILDDCNEKIDTELASHIVDLHMKRDEAiEPPFSAEQLRRYIKYARTFKPILTKE 768
Cdd:cd17760 159 YDPNESISVNIALASPLLSRFDLVLVLLDTKNEDWDRIISSFILENKGEPSKS-SKLWSMEKMRTYFCLIKNLRPVLSDE 237
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
6PTN_m 769 ARSYLVEKYKELRKDDaqgfSRSSYRITVRQLESMIRLSEAIARANCVDEIT 820
Cdd:cd17760 238 ANAILLRYYQLQRQSD----CRNAARTTIRMLESLIRLAEAHARLMFRETVT 285
|
|
| PTZ00111 |
PTZ00111 |
DNA replication licensing factor MCM4; Provisional |
254-852 |
2.16e-81 |
|
DNA replication licensing factor MCM4; Provisional
Pssm-ID: 173403 [Multi-domain] Cd Length: 915 Bit Score: 284.19 E-value: 2.16e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 254 TSPEQTERVFQISFFNLPTVHRIRDIRSEKIGSLLSISGTVTRTSEVRPELYKASFTCDMCRAI-VDNVE----QSFKYT 328
Cdd:PTZ00111 196 LSLENNSFFPRARLMNKPVSDCVGNLEPSMADSLVQFSGTVVRQTWIVPEITMACFRCRGQKKIgLNDYQpctcEHYEYV 275
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 329 ------EPTFCPNpsCENRAFWTLNVTRSRFLDWQKVRIQENANEIPTGSMPRTldvilrGDSVERAKPGDRCKFTGVEI 402
Cdd:PTZ00111 276 iqgevnEPLLCNE--CNSKYTFELNHNMCVYSTKKIVKLLQSNSSLNNPDKDGL------DNSVDNSGLNGEIYMKDNEV 347
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 403 VVPDVTQLGLPGVKPSSTLDTRGISKTTE-GLNSGVTGLRSLgvrdLTYKISFLACHVIsigsnigasspdaNSNNrete 481
Cdd:PTZ00111 348 INLNLYDDLIDSVKTGDRVTVVGILKVTPiRTSTTRRTLKSL----YTYFVNVIHVKVI-------------NSTN---- 406
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 482 lqmAANLQANNVYQDNErdqevflNSLSSDEINELKEMVKDEHIYDKLVRSIAPAVFGHEAVKKGILLQMLGG------- 554
Cdd:PTZ00111 407 ---ANQPEKGLKYLGNE-------NDFSDLQVYKILELSRNPMIYRILLDSFAPSIKARNNVKIGLLCQLFSGnknssdf 476
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 555 --VHKSTVEGIKLRGDINICVVGDPSTSKSQFLKYVVGFAPRSVYTSGKASSAAGLTAAV-VRDEEGGDYTIEAGALMLA 631
Cdd:PTZ00111 477 nkSPDACYKVDNFRGIINVLLCGDPGTAKSQLLHYTHLLSPRSIYTSGKSSSSVGLTASIkFNESDNGRAMIQPGAVVLA 556
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 632 DNGICCIDEFDKMDISDQVAIHEAMEQQTISIAKAGIHATLNARTSILAAANPVGGRYNRKLSLRGNLNMTAPIMSRFDL 711
Cdd:PTZ00111 557 NGGVCCIDELDKCHNESRLSLYEVMEQQTVTIAKAGIVATLKAETAILASCNPINSRYNKNKAVIENINISPSLFTRFDL 636
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 712 FFVILDDCNEKIDTELASHIV---------------DLHMKR------DEAIEPPFS-----AEQLRRYIKYAR-TFKPI 764
Cdd:PTZ00111 637 IYLVLDHIDQDTDQLISLSIAkdfllphmtgsgndeDTYDRSntmhveDESLRSEKDynkndLDMLRMYIKFSKlHCFPK 716
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 765 LTKEARSYLVEKYKELRK-------------------DDAQGFSRSSYRITV--RQLESMIRLSEAIARANCVDEITPSF 823
Cdd:PTZ00111 717 LSDEAKKVITREYVKMRQgnfqtsnldelehaqedddDDLYYQSSGTRMIYVssRMISSIIRISVSLARMRLSTVVTPAD 796
|
650 660
....*....|....*....|....*....
6PTN_m 824 IAEAYDLLRQSIIRVDVDDVEMDEEFDNI 852
Cdd:PTZ00111 797 ALQAVQIVKSSTFQSLVDPTTGKIDFDQL 825
|
|
| MCM_OB |
pfam17207 |
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains ... |
275-405 |
1.02e-61 |
|
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains an insertion at the zinc binding motif.
Pssm-ID: 465381 [Multi-domain] Cd Length: 126 Bit Score: 205.41 E-value: 1.02e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 275 RIRDIRSEKIGSLLSISGTVTRTSEVRPELYKASFTCDMCRAIVdnveqSFKYTEPTFCPNPSCENRAFWTLNVTRSRFL 354
Cdd:pfam17207 1 SIRDLRSEHIGKLVSVSGIVTRTSEVRPKLKKATFTCRKCGHTV-----GVKITEPTKCPNPECGNKDPFKLVHEKSKFV 75
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
6PTN_m 355 DWQKVRIQENANEIPTGSMPRTLDVILRGDSVERAKPGDRCKFTGVEIVVP 405
Cdd:pfam17207 76 DFQKIKIQESPEEVPAGELPRSLDVILDDDLVDRVKPGDRVTVTGIYRVVP 126
|
|
| MCM6_C |
pfam18263 |
MCM6 C-terminal winged-helix domain; The minichromosome maintenance (Mcm) complex is the ... |
900-1007 |
3.29e-37 |
|
MCM6 C-terminal winged-helix domain; The minichromosome maintenance (Mcm) complex is the replicative helicase in eukaryotic species, that plays essential roles in the initiation and elongation phases of DNA replication. During late M and early G(1), the Mcm complex is loaded onto chromatin to form prereplicative complex in a Cdt1-dependent manner. This entry represents the C-terminal domain of human Mcm6 which is the Cdt1 binding domain (CBD). The structure of CBD exhibits a typical winged helix fold that is generally involved in protein-nucleic acid interaction. The CBD failed to interact with DNA in experiments. The CBD-Cdt1 interaction involves the helix-turn-helix motif of CBD.
Pssm-ID: 465688 Cd Length: 107 Bit Score: 135.02 E-value: 3.29e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 900 KKTTVTYDKYVSMMNMIVRKIAEVDREGAEELTAVDIVDWYLLQKENDLGSLAEYWEERRLAFKVIKRLVKDRILMEIHG 979
Cdd:pfam18263 1 KKLRITYDKYVKIMNLLVLHLREVEEEEGEGVDRSELIQWYLEQIEDEIESEEELEEEKELVEKVIKRLIKDNILLEIRG 80
|
90 100
....*....|....*....|....*...
6PTN_m 980 TRhNLRDLENEENENNKTVYVIHPNCEV 1007
Cdd:pfam18263 81 EG-LEDEGEEDAEEEEDPVLVVHPNYDI 107
|
|
| MCM_lid |
pfam17855 |
MCM AAA-lid domain; This entry represents the AAA-lid domain found in MCM proteins. |
749-835 |
1.57e-31 |
|
MCM AAA-lid domain; This entry represents the AAA-lid domain found in MCM proteins.
Pssm-ID: 465534 [Multi-domain] Cd Length: 86 Bit Score: 118.03 E-value: 1.57e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 749 EQLRRYIKYAR-TFKPILTKEARSYLVEKYKELRKDDAQgfSRSSYRITVRQLESMIRLSEAIARANCVDEITPSFIAEA 827
Cdd:pfam17855 1 ELLRKYIAYAReKIKPKLSEEAREKLVDAYVELRKESTG--SGSSIPITVRQLESLIRLSEAHAKMRLSEIVTEEDVEEA 78
|
....*...
6PTN_m 828 YDLLRQSI 835
Cdd:pfam17855 79 IRLLKESL 86
|
|
| MCM_N |
pfam14551 |
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins. |
112-195 |
4.36e-19 |
|
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins.
Pssm-ID: 464206 [Multi-domain] Cd Length: 95 Bit Score: 83.11 E-value: 4.36e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 112 REAFEQFLEDFSVQSTDtgevEKVYRAQIEFMKIYDLNTIYIDYQHLSMRENGaLAMAISEQYYRFLPFLQKGLRRVVRK 191
Cdd:pfam14551 1 KRKFKDFLEEFREDGDG----EFKYRDQLREMIEREQRSLEVDLDDLREFDPD-LAEALLENPYEYLPLFEEALKEVVKE 75
|
....
6PTN_m 192 YAPE 195
Cdd:pfam14551 76 LSED 79
|
|
| PRK09862 |
PRK09862 |
ATP-dependent protease; |
537-827 |
2.82e-07 |
|
ATP-dependent protease;
Pssm-ID: 182120 [Multi-domain] Cd Length: 506 Bit Score: 54.22 E-value: 2.82e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 537 VFGHEAVKKGILLQMLGGvHkstvegiklrgdiNICVVGDPSTSKSQFLKYVVGFAP----------RSVYTSGKASS-- 604
Cdd:PRK09862 193 VIGQEQGKRGLEITAAGG-H-------------NLLLIGPPGTGKTMLASRINGLLPdlsneealesAAILSLVNAESvq 258
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 605 -------------AAGLTAAVvrdeeGGDYTIEAGALMLADNGICCIDEFDKMDISDQVAIHEAMEQQTISIAKAGIHAT 671
Cdd:PRK09862 259 kqwrqrpfrsphhSASLTAMV-----GGGAIPGPGEISLAHNGVLFLDELPEFERRTLDALREPIESGQIHLSRTRAKIT 333
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 672 LNARTSILAAANP-----VGGRYNR---KLSLRGNLNMTAPIMSRFDLffvilddcneKIDTEL-ASHIVDLHMKRDEAi 742
Cdd:PRK09862 334 YPARFQLVAAMNPsptghYQGNHNRctpEQTLRYLNRLSGPFLDRFDL----------SLEIPLpPPGILSKTVVPGES- 402
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6PTN_m 743 eppfSAEQLRRYI-----KYARTFKpiLTKEARSYLVEKYKELRKDDAQGFSRSSYR--ITVRQLESMIRLSEAIARANC 815
Cdd:PRK09862 403 ----SATVKQRVMaarerQFKRQNK--LNAWLDSPEIRQFCKLESEDARWLEETLIHlgLSIRAWQRLLKVARTIADIDQ 476
|
330
....*....|..
6PTN_m 816 VDEITPSFIAEA 827
Cdd:PRK09862 477 SDIITRQHLQEA 488
|
|
| |
