|
Name |
Accession |
Description |
Interval |
E-value |
| Eno |
COG0148 |
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: ... |
2-434 |
0e+00 |
|
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439918 [Multi-domain] Cd Length: 426 Bit Score: 888.21 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 2 MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTGEHEAVELRDGDKSRYLGLGTQKAVDNVNNIIAEAII 81
Cdd:COG0148 1 MSRIEDVHAREILDSRGNPTVEVEVTLEDGAVGRAAVPSGASTGSHEAVELRDGDKSRYLGKGVLKAVENVNEEIAPALI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 82 GYDVRDQQAIDRAMIALDGTPNKGKLGANAILGVSIAVARAAADYLEVPLYTYLGGFNTKVLPTPMMNIINGGSHSDAPI 161
Cdd:COG0148 81 GMDATDQRAIDRAMIELDGTPNKSRLGANAILGVSLAVAKAAAAALGLPLYRYLGGVNAKTLPVPMMNIINGGAHADNNV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 162 AFQEFMIMPVGAPTFKEGLRWGAEVFHALKKILKERGLVTAVGDEGGFAPKFEGTEDGVETILKAIEAAGYEAGENgIMI 241
Cdd:COG0148 161 DIQEFMIMPVGAPSFSEALRMGAEVFHALKKVLKEKGLSTAVGDEGGFAPNLKSNEEALELILEAIEKAGYKPGED-IAL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 242 GFDCASSEFYDAERavYDytkFEGEGaAVRTSAEQVDYLEELVNKYPIITIEDGMDENDWDGWKVLTERLGKRVQLVGDD 321
Cdd:COG0148 240 ALDVAASEFYKDGK--YH---LKGEG-KELTSEEMIDYYADLVDKYPIVSIEDGLAEDDWDGWKLLTEKLGDKVQLVGDD 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 322 FFVTNTEYLARGIKENAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQIKTGSLS 401
Cdd:COG0148 314 LFVTNPKRLKKGIEEGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSPS 393
|
410 420 430
....*....|....*....|....*....|...
8DG4_E 402 RTDRIAKYNQLLRIEDQLGEVAQYKGIKSFYNL 434
Cdd:COG0148 394 RSERVAKYNQLLRIEEELGDAARYAGRSAFKRL 426
|
|
| eno |
PRK00077 |
enolase; Provisional |
2-435 |
0e+00 |
|
enolase; Provisional
Pssm-ID: 234617 [Multi-domain] Cd Length: 425 Bit Score: 860.16 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 2 MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTGEHEAVELRDGDKSRYLGLGTQKAVDNVNNIIAEAII 81
Cdd:PRK00077 1 MSKIEDIIAREILDSRGNPTVEVEVTLEDGAFGRAAVPSGASTGEREAVELRDGDKSRYLGKGVLKAVENVNEEIAPALI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 82 GYDVRDQQAIDRAMIALDGTPNKGKLGANAILGVSIAVARAAADYLEVPLYTYLGGFNTKVLPTPMMNIINGGSHSDAPI 161
Cdd:PRK00077 81 GLDALDQRAIDKAMIELDGTPNKSKLGANAILGVSLAVAKAAADSLGLPLYRYLGGPNAKVLPVPMMNIINGGAHADNNV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 162 AFQEFMIMPVGAPTFKEGLRWGAEVFHALKKILKERGLVTAVGDEGGFAPKFEGTEDGVETILKAIEAAGYEAGENgIMI 241
Cdd:PRK00077 161 DIQEFMIMPVGAPSFKEALRMGAEVFHTLKKVLKEKGLSTAVGDEGGFAPNLKSNEEALDLILEAIEKAGYKPGED-IAL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 242 GFDCASSEFYDAERavYDytkFEGEGaavRTSAEQVDYLEELVNKYPIITIEDGMDENDWDGWKVLTERLGKRVQLVGDD 321
Cdd:PRK00077 240 ALDCAASEFYKDGK--YV---LEGEG---LTSEEMIDYLAELVDKYPIVSIEDGLDENDWEGWKLLTEKLGDKVQLVGDD 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 322 FFVTNTEYLARGIKENAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQIKTGSLS 401
Cdd:PRK00077 312 LFVTNTKRLKKGIEKGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVVSHRSGETEDTTIADLAVATNAGQIKTGSLS 391
|
410 420 430
....*....|....*....|....*....|....
8DG4_E 402 RTDRIAKYNQLLRIEDQLGEVAQYKGIKSFYNLA 435
Cdd:PRK00077 392 RSERIAKYNQLLRIEEELGDAARYAGKKAFKNLK 425
|
|
| enolase |
cd03313 |
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of ... |
7-418 |
0e+00 |
|
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions.
Pssm-ID: 239429 [Multi-domain] Cd Length: 408 Bit Score: 745.84 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 7 DVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTGEHEAVELRDGDKSRYLGLGTQKAVDNVNNIIAEAIIGYDVR 86
Cdd:cd03313 1 KIKAREILDSRGNPTVEVEVTTEDGGVGRAAVPSGASTGEHEAVELRDGDKSRYLGKGVLKAVKNVNEIIAPALIGMDVT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 87 DQQAIDRAMIALDGTPNKGKLGANAILGVSIAVARAAADYLEVPLYTYLGGFNTKVLPTPMMNIINGGSHSDAPIAFQEF 166
Cdd:cd03313 81 DQRAIDKLLIELDGTPNKSKLGANAILGVSLAVAKAAAAALGLPLYRYLGGLAAYVLPVPMFNVINGGAHAGNKLDFQEF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 167 MIMPVGAPTFKEGLRWGAEVFHALKKILKERG--LVTAVGDEGGFAPKFEGTEDGVETILKAIEAAGYEAGENgIMIGFD 244
Cdd:cd03313 161 MIVPVGAPSFSEALRMGAEVYHTLKKVLKKKGglLATNVGDEGGFAPNLSSNEEALDLLVEAIEKAGYEPGKK-IAIALD 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 245 CASSEFYDAERavYDYTKFEGEgaaVRTSAEQVDYLEELVNKYPIITIEDGMDENDWDGWKVLTERLGKRVQLVGDDFFV 324
Cdd:cd03313 240 VAASEFYDEGK--YVYDSDEGK---KLTSEELIDYYKELVKKYPIVSIEDPFDEDDWEGWAKLTAKLGDKIQIVGDDLFV 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 325 TNTEYLARGIKENAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQIKTGSLSRTD 404
Cdd:cd03313 315 TNPERLKKGIEKKAANALLIKVNQIGTLTETIEAIKLAKKNGYGVVVSHRSGETEDTFIADLAVALGAGQIKTGAPCRSE 394
|
410
....*....|....
8DG4_E 405 RIAKYNQLLRIEDQ 418
Cdd:cd03313 395 RTAKYNQLLRIEEE 408
|
|
| eno |
TIGR01060 |
phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis ... |
5-434 |
0e+00 |
|
phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 213580 [Multi-domain] Cd Length: 425 Bit Score: 731.08 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 5 ITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTGEHEAVELRDGDKSRYLGLGTQKAVDNVNNIIAEAIIGYD 84
Cdd:TIGR01060 1 IVDIRAREILDSRGNPTVEVEVILEDGTFGRAAVPSGASTGEREALELRDGDKKRYLGKGVLKAVENVNEIIAPELIGMD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 85 VRDQQAIDRAMIALDGTPNKGKLGANAILGVSIAVARAAADYLEVPLYTYLGGFNTKVLPTPMMNIINGGSHSDAPIAFQ 164
Cdd:TIGR01060 81 ATDQREIDQILIELDGTPNKSKLGANAILGVSMAVAKAAADSLGLPLYRYLGGFNAYVLPVPMMNIINGGAHADNNLDFQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 165 EFMIMPVGAPTFKEGLRWGAEVFHALKKILKERGLVTAVGDEGGFAPKFEGTEDGVETILKAIEAAGYEAGENgIMIGFD 244
Cdd:TIGR01060 161 EFMIMPVGAPSFREALRMGAEVFHALKKLLKEKGLATGVGDEGGFAPNLASNEEALEIIVEAIEKAGYKPGED-VALALD 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 245 CASSEFYDAERAVYdytKFEGEGAAvRTSAEQVDYLEELVNKYPIITIEDGMDENDWDGWKVLTERLGKRVQLVGDDFFV 324
Cdd:TIGR01060 240 CAASEFYDEEDGKY---VYKGENKQ-LTSEEMIEYYEELVEKYPIISIEDGLSEEDWEGWAELTKRLGDKVQIVGDDLFV 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 325 TNTEYLARGIKENAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQIKTGSLSRTD 404
Cdd:TIGR01060 316 TNTEILREGIEMGVANSILIKPNQIGTLTETLDAIELAKKAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSLSRSE 395
|
410 420 430
....*....|....*....|....*....|
8DG4_E 405 RIAKYNQLLRIEDQLGEVAQYKGIKSFYNL 434
Cdd:TIGR01060 396 RIAKYNQLLRIEEELGDSARYAGKNSFYRF 425
|
|
| Enolase_C |
pfam00113 |
Enolase, C-terminal TIM barrel domain; |
140-434 |
6.20e-152 |
|
Enolase, C-terminal TIM barrel domain;
Pssm-ID: 395063 Cd Length: 296 Bit Score: 432.67 E-value: 6.20e-152
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 140 TKVLPTPMMNIINGGSHSDAPIAFQEFMIMPVGAPTFKEGLRWGAEVFHALKKILKERG--LVTAVGDEGGFAPKFEGTE 217
Cdd:pfam00113 1 SYVLPVPMMNVINGGSHAGNNLAFQEFMILPTGAPSFSEAMRMGAEVYHHLKSVLKAKYgqSATNVGDEGGFAPNLQSNK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 218 DGVETILKAIEAAGYEAGengIMIGFDCASSEFYDAERAVYDYtKFEGE---GAAVRTSAEQVDYLEELVNKYPIITIED 294
Cdd:pfam00113 81 EALDLIVEAIEKAGYKGK---IKIAMDVASSEFYNKKDGKYDL-DFKGEksdKSKKLTSAQLADLYEELVKKYPIVSIED 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 295 GMDENDWDGWKVLTERLGKRVQLVGDDFFVTNTEYLARGIKENAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHR 374
Cdd:pfam00113 157 PFDEDDWEAWKYLTERLGDKVQIVGDDLTVTNPKRLKTAIEKKIANALLLKVNQIGSLTESIAAVKMAKDAGWGVMVSHR 236
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 375 SGETEDSTIADIAVATNAGQIKTGSLSRTDRIAKYNQLLRIEDQLGEVAQYKGIKSFYNL 434
Cdd:pfam00113 237 SGETEDTTIADLAVGLNAGQIKTGAPCRSERLAKYNQLLRIEEELGSEAKYAGRSFRKPL 296
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| Eno |
COG0148 |
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: ... |
2-434 |
0e+00 |
|
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439918 [Multi-domain] Cd Length: 426 Bit Score: 888.21 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 2 MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTGEHEAVELRDGDKSRYLGLGTQKAVDNVNNIIAEAII 81
Cdd:COG0148 1 MSRIEDVHAREILDSRGNPTVEVEVTLEDGAVGRAAVPSGASTGSHEAVELRDGDKSRYLGKGVLKAVENVNEEIAPALI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 82 GYDVRDQQAIDRAMIALDGTPNKGKLGANAILGVSIAVARAAADYLEVPLYTYLGGFNTKVLPTPMMNIINGGSHSDAPI 161
Cdd:COG0148 81 GMDATDQRAIDRAMIELDGTPNKSRLGANAILGVSLAVAKAAAAALGLPLYRYLGGVNAKTLPVPMMNIINGGAHADNNV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 162 AFQEFMIMPVGAPTFKEGLRWGAEVFHALKKILKERGLVTAVGDEGGFAPKFEGTEDGVETILKAIEAAGYEAGENgIMI 241
Cdd:COG0148 161 DIQEFMIMPVGAPSFSEALRMGAEVFHALKKVLKEKGLSTAVGDEGGFAPNLKSNEEALELILEAIEKAGYKPGED-IAL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 242 GFDCASSEFYDAERavYDytkFEGEGaAVRTSAEQVDYLEELVNKYPIITIEDGMDENDWDGWKVLTERLGKRVQLVGDD 321
Cdd:COG0148 240 ALDVAASEFYKDGK--YH---LKGEG-KELTSEEMIDYYADLVDKYPIVSIEDGLAEDDWDGWKLLTEKLGDKVQLVGDD 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 322 FFVTNTEYLARGIKENAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQIKTGSLS 401
Cdd:COG0148 314 LFVTNPKRLKKGIEEGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSPS 393
|
410 420 430
....*....|....*....|....*....|...
8DG4_E 402 RTDRIAKYNQLLRIEDQLGEVAQYKGIKSFYNL 434
Cdd:COG0148 394 RSERVAKYNQLLRIEEELGDAARYAGRSAFKRL 426
|
|
| eno |
PRK00077 |
enolase; Provisional |
2-435 |
0e+00 |
|
enolase; Provisional
Pssm-ID: 234617 [Multi-domain] Cd Length: 425 Bit Score: 860.16 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 2 MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTGEHEAVELRDGDKSRYLGLGTQKAVDNVNNIIAEAII 81
Cdd:PRK00077 1 MSKIEDIIAREILDSRGNPTVEVEVTLEDGAFGRAAVPSGASTGEREAVELRDGDKSRYLGKGVLKAVENVNEEIAPALI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 82 GYDVRDQQAIDRAMIALDGTPNKGKLGANAILGVSIAVARAAADYLEVPLYTYLGGFNTKVLPTPMMNIINGGSHSDAPI 161
Cdd:PRK00077 81 GLDALDQRAIDKAMIELDGTPNKSKLGANAILGVSLAVAKAAADSLGLPLYRYLGGPNAKVLPVPMMNIINGGAHADNNV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 162 AFQEFMIMPVGAPTFKEGLRWGAEVFHALKKILKERGLVTAVGDEGGFAPKFEGTEDGVETILKAIEAAGYEAGENgIMI 241
Cdd:PRK00077 161 DIQEFMIMPVGAPSFKEALRMGAEVFHTLKKVLKEKGLSTAVGDEGGFAPNLKSNEEALDLILEAIEKAGYKPGED-IAL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 242 GFDCASSEFYDAERavYDytkFEGEGaavRTSAEQVDYLEELVNKYPIITIEDGMDENDWDGWKVLTERLGKRVQLVGDD 321
Cdd:PRK00077 240 ALDCAASEFYKDGK--YV---LEGEG---LTSEEMIDYLAELVDKYPIVSIEDGLDENDWEGWKLLTEKLGDKVQLVGDD 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 322 FFVTNTEYLARGIKENAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQIKTGSLS 401
Cdd:PRK00077 312 LFVTNTKRLKKGIEKGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVVSHRSGETEDTTIADLAVATNAGQIKTGSLS 391
|
410 420 430
....*....|....*....|....*....|....
8DG4_E 402 RTDRIAKYNQLLRIEDQLGEVAQYKGIKSFYNLA 435
Cdd:PRK00077 392 RSERIAKYNQLLRIEEELGDAARYAGKKAFKNLK 425
|
|
| enolase |
cd03313 |
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of ... |
7-418 |
0e+00 |
|
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions.
Pssm-ID: 239429 [Multi-domain] Cd Length: 408 Bit Score: 745.84 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 7 DVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTGEHEAVELRDGDKSRYLGLGTQKAVDNVNNIIAEAIIGYDVR 86
Cdd:cd03313 1 KIKAREILDSRGNPTVEVEVTTEDGGVGRAAVPSGASTGEHEAVELRDGDKSRYLGKGVLKAVKNVNEIIAPALIGMDVT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 87 DQQAIDRAMIALDGTPNKGKLGANAILGVSIAVARAAADYLEVPLYTYLGGFNTKVLPTPMMNIINGGSHSDAPIAFQEF 166
Cdd:cd03313 81 DQRAIDKLLIELDGTPNKSKLGANAILGVSLAVAKAAAAALGLPLYRYLGGLAAYVLPVPMFNVINGGAHAGNKLDFQEF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 167 MIMPVGAPTFKEGLRWGAEVFHALKKILKERG--LVTAVGDEGGFAPKFEGTEDGVETILKAIEAAGYEAGENgIMIGFD 244
Cdd:cd03313 161 MIVPVGAPSFSEALRMGAEVYHTLKKVLKKKGglLATNVGDEGGFAPNLSSNEEALDLLVEAIEKAGYEPGKK-IAIALD 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 245 CASSEFYDAERavYDYTKFEGEgaaVRTSAEQVDYLEELVNKYPIITIEDGMDENDWDGWKVLTERLGKRVQLVGDDFFV 324
Cdd:cd03313 240 VAASEFYDEGK--YVYDSDEGK---KLTSEELIDYYKELVKKYPIVSIEDPFDEDDWEGWAKLTAKLGDKIQIVGDDLFV 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 325 TNTEYLARGIKENAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQIKTGSLSRTD 404
Cdd:cd03313 315 TNPERLKKGIEKKAANALLIKVNQIGTLTETIEAIKLAKKNGYGVVVSHRSGETEDTFIADLAVALGAGQIKTGAPCRSE 394
|
410
....*....|....
8DG4_E 405 RIAKYNQLLRIEDQ 418
Cdd:cd03313 395 RTAKYNQLLRIEEE 408
|
|
| eno |
TIGR01060 |
phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis ... |
5-434 |
0e+00 |
|
phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 213580 [Multi-domain] Cd Length: 425 Bit Score: 731.08 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 5 ITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTGEHEAVELRDGDKSRYLGLGTQKAVDNVNNIIAEAIIGYD 84
Cdd:TIGR01060 1 IVDIRAREILDSRGNPTVEVEVILEDGTFGRAAVPSGASTGEREALELRDGDKKRYLGKGVLKAVENVNEIIAPELIGMD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 85 VRDQQAIDRAMIALDGTPNKGKLGANAILGVSIAVARAAADYLEVPLYTYLGGFNTKVLPTPMMNIINGGSHSDAPIAFQ 164
Cdd:TIGR01060 81 ATDQREIDQILIELDGTPNKSKLGANAILGVSMAVAKAAADSLGLPLYRYLGGFNAYVLPVPMMNIINGGAHADNNLDFQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 165 EFMIMPVGAPTFKEGLRWGAEVFHALKKILKERGLVTAVGDEGGFAPKFEGTEDGVETILKAIEAAGYEAGENgIMIGFD 244
Cdd:TIGR01060 161 EFMIMPVGAPSFREALRMGAEVFHALKKLLKEKGLATGVGDEGGFAPNLASNEEALEIIVEAIEKAGYKPGED-VALALD 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 245 CASSEFYDAERAVYdytKFEGEGAAvRTSAEQVDYLEELVNKYPIITIEDGMDENDWDGWKVLTERLGKRVQLVGDDFFV 324
Cdd:TIGR01060 240 CAASEFYDEEDGKY---VYKGENKQ-LTSEEMIEYYEELVEKYPIISIEDGLSEEDWEGWAELTKRLGDKVQIVGDDLFV 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 325 TNTEYLARGIKENAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQIKTGSLSRTD 404
Cdd:TIGR01060 316 TNTEILREGIEMGVANSILIKPNQIGTLTETLDAIELAKKAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSLSRSE 395
|
410 420 430
....*....|....*....|....*....|
8DG4_E 405 RIAKYNQLLRIEDQLGEVAQYKGIKSFYNL 434
Cdd:TIGR01060 396 RIAKYNQLLRIEEELGDSARYAGKNSFYRF 425
|
|
| PTZ00081 |
PTZ00081 |
enolase; Provisional |
2-427 |
0e+00 |
|
enolase; Provisional
Pssm-ID: 240259 [Multi-domain] Cd Length: 439 Bit Score: 578.93 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 2 MSIITDVYAREVLDSRGNPTLEVEVYTESGAFgRGMVPSGASTGEHEAVELRDGDKSRYLGLGTQKAVDNVNNIIAEAII 81
Cdd:PTZ00081 1 MSTIKSIKAREILDSRGNPTVEVDLTTEKGVF-RAAVPSGASTGIYEALELRDGDKSRYLGKGVLKAVENVNEIIAPALI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 82 GYDVRDQQAIDRAMI-ALDGTPN-----KGKLGANAILGVSIAVARAAADYLEVPLYTYLGGFNTK-----VLPTPMMNI 150
Cdd:PTZ00081 80 GKDVTDQKKLDKLMVeQLDGTKNewgwcKSKLGANAILAVSMAVARAAAAAKGVPLYKYLAQLAGKptdkfVLPVPCFNV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 151 INGGSHSDAPIAFQEFMIMPVGAPTFKEGLRWGAEVFHALKKILKER-GL-VTAVGDEGGFAPKFEGTEDGVETILKAIE 228
Cdd:PTZ00081 160 INGGKHAGNKLAFQEFMIAPVGAPSFKEALRMGAEVYHSLKSVIKKKyGLdATNVGDEGGFAPNIKDPEEALDLLVEAIK 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 229 AAGYEAGengIMIGFDCASSEFYDAERAVYD--YTKFEGEGAAVRTSAEQVDYLEELVNKYPIITIEDGMDENDWDGWKV 306
Cdd:PTZ00081 240 KAGYEGK---VKICMDVAASEFYDKEKKVYDldFKNPNNDKSNKLTGEELVELYLDLVKKYPIVSIEDPFDQDDWEAYAK 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 307 LTERLGKRVQLVGDDFFVTNTEYLARGIKENAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADI 386
Cdd:PTZ00081 317 LTAAIGQKVQIVGDDLLVTNPTRIKKAIEKKACNALLLKVNQIGTVTEAIEAAKLAQKNGWGVMVSHRSGETEDTFIADL 396
|
410 420 430 440
....*....|....*....|....*....|....*....|.
8DG4_E 387 AVATNAGQIKTGSLSRTDRIAKYNQLLRIEDQLGEVAQYKG 427
Cdd:PTZ00081 397 VVGLGTGQIKTGAPCRSERLAKYNQLLRIEEELGSNAVYAG 437
|
|
| PLN00191 |
PLN00191 |
enolase |
2-427 |
0e+00 |
|
enolase
Pssm-ID: 215095 [Multi-domain] Cd Length: 457 Bit Score: 538.14 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 2 MSIITDVYAREVLDSRGNPTLEVEVYTESGAFgRGMVPSGASTGEHEAVELRDGDKsRYLGLGTQKAVDNVNNIIAEAII 81
Cdd:PLN00191 25 MATITKVKARQIIDSRGNPTVEVDLHTSKGMF-RAAVPSGASTGIYEALELRDGDK-DYLGKGVLKAVKNVNEIIAPALI 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 82 GYDVRDQQAIDRAMIALDGTPNKGKLGANAILGVSIAVARAAADYLEVPLYTY---LGGFNTKVLPTPMMNIINGGSHSD 158
Cdd:PLN00191 103 GMDPTDQTQIDNFMLELDGTPNKGKLGANAILAVSLAVCKAGAAEKGVPLYKHiadLAGNKKLVLPVPAFNVINGGSHAG 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 159 APIAFQEFMIMPVGAPTFKEGLRWGAEVFHALKKILKER--GLVTAVGDEGGFAPKFEGTEDGVETILKAIEAAGYeage 236
Cdd:PLN00191 183 NKLAMQEFMILPVGASSFKEAMQMGSEVYHHLKAVIKKKygQDACNVGDEGGFAPNIQDNKEGLELLKEAIEKAGY---- 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 237 NG-IMIGFDCASSEFYDAERAvYD--YTKFEGEGAAVRTSAEQVDYLEELVNKYPIITIEDGMDENDWDGWKVLTERlgK 313
Cdd:PLN00191 259 TGkIKIGMDVAASEFYTKDKK-YDldFKEENNDGSNKKSGDELIDLYKEFVSDYPIVSIEDPFDQDDWEHWAKLTSL--E 335
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 314 RVQLVGDDFFVTNTEYLARGIKENAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAG 393
Cdd:PLN00191 336 DVQIVGDDLLVTNPKRVAKAIQEKACNALLLKVNQIGTVTESIEAVKMSKAAGWGVMTSHRSGETEDSFIADLAVGLATG 415
|
410 420 430
....*....|....*....|....*....|....
8DG4_E 394 QIKTGSLSRTDRIAKYNQLLRIEDQLGEVAQYKG 427
Cdd:PLN00191 416 QIKTGAPCRSERLAKYNQLLRIEEELGDEAVYAG 449
|
|
| Enolase_C |
pfam00113 |
Enolase, C-terminal TIM barrel domain; |
140-434 |
6.20e-152 |
|
Enolase, C-terminal TIM barrel domain;
Pssm-ID: 395063 Cd Length: 296 Bit Score: 432.67 E-value: 6.20e-152
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 140 TKVLPTPMMNIINGGSHSDAPIAFQEFMIMPVGAPTFKEGLRWGAEVFHALKKILKERG--LVTAVGDEGGFAPKFEGTE 217
Cdd:pfam00113 1 SYVLPVPMMNVINGGSHAGNNLAFQEFMILPTGAPSFSEAMRMGAEVYHHLKSVLKAKYgqSATNVGDEGGFAPNLQSNK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 218 DGVETILKAIEAAGYEAGengIMIGFDCASSEFYDAERAVYDYtKFEGE---GAAVRTSAEQVDYLEELVNKYPIITIED 294
Cdd:pfam00113 81 EALDLIVEAIEKAGYKGK---IKIAMDVASSEFYNKKDGKYDL-DFKGEksdKSKKLTSAQLADLYEELVKKYPIVSIED 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 295 GMDENDWDGWKVLTERLGKRVQLVGDDFFVTNTEYLARGIKENAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHR 374
Cdd:pfam00113 157 PFDEDDWEAWKYLTERLGDKVQIVGDDLTVTNPKRLKTAIEKKIANALLLKVNQIGSLTESIAAVKMAKDAGWGVMVSHR 236
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 375 SGETEDSTIADIAVATNAGQIKTGSLSRTDRIAKYNQLLRIEDQLGEVAQYKGIKSFYNL 434
Cdd:pfam00113 237 SGETEDTTIADLAVGLNAGQIKTGAPCRSERLAKYNQLLRIEEELGSEAKYAGRSFRKPL 296
|
|
| Enolase_N |
pfam03952 |
Enolase, N-terminal domain; |
5-135 |
2.15e-90 |
|
Enolase, N-terminal domain;
Pssm-ID: 461105 [Multi-domain] Cd Length: 131 Bit Score: 269.63 E-value: 2.15e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 5 ITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTGEHEAVELRDGDKSRYLGLGTQKAVDNVNNIIAEAIIGYD 84
Cdd:pfam03952 1 ITKVKAREILDSRGNPTVEVEVTLEDGTFGRAAVPSGASTGEHEAVELRDGDKSRYGGKGVLKAVENVNEIIAPALIGMD 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
8DG4_E 85 VRDQQAIDRAMIALDGTPNKGKLGANAILGVSIAVARAAADYLEVPLYTYL 135
Cdd:pfam03952 81 ATDQRAIDRALIELDGTENKSKLGANAILGVSLAVAKAAAAALGLPLYRYL 131
|
|
| PRK08350 |
PRK08350 |
hypothetical protein; Provisional |
2-421 |
2.28e-21 |
|
hypothetical protein; Provisional
Pssm-ID: 169397 [Multi-domain] Cd Length: 341 Bit Score: 94.49 E-value: 2.28e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 2 MSIITDVYAREVLDSRGNPTLEVEVYTESGaFGRGMVPSgastgeheavelrDGDKSRYLGlGTQKAVDNVNNIIAEAII 81
Cdd:PRK08350 1 MTVIENIIGRVAVLRGGKYSVEVDVITDSG-FGRFAAPI-------------DENPSLYIA-EAHRAVSEVDEIIGPELI 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 82 GYDVRDQQAIDRAMIALDGTPNKGKLGANAILGVSIAVARAAADYLEVPLYTYLGGFNTKVLPTPMMNIINgGSHSDAPI 161
Cdd:PRK08350 66 GFDASEQELIDSYLWEIDGTEDFSHIGANTALAVSVAVAKAAANSKNMPLYSYIGGTFTTELPVPILEFAE-DENFEYYV 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 162 AFQEFMIMpvgaptfkeglrwgAEVFHALKKILKERGLVTavgdeggfapkfegtedgVETILKAIEAAGYEagengimI 241
Cdd:PRK08350 145 LVRDLMEI--------------TDVVDAVNKILENSKEVS------------------LEGLSKASEKAGDE-------L 185
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 242 GFDCASsefydaeravydytkfegeGAAVRTSAEQVDYLeELVNKYPIITIEDGMDEndwdgwKVLTERLGkrvqlvGDD 321
Cdd:PRK08350 186 GLEVAL-------------------GIAQKREMETEKVL-NLVEDNNIAYIKPIGDE------ELFLELIA------GTH 233
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 322 FFVTNTEYLARG---IKENAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQIktg 398
Cdd:PRK08350 234 GVFIDGEYLFRTrniLDRRYYNALSIKPINLGTLTDLYNLVNDVKSERITPILAEAKYESADEALPHLAVGLRCPAM--- 310
|
410 420
....*....|....*....|...
8DG4_E 399 sLSRTDRIAKYNQLLRIEDQLGE 421
Cdd:PRK08350 311 -LIHKDSVEKINELNRIAEDLGE 332
|
|
| enolase_like |
cd00308 |
Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is ... |
284-397 |
5.77e-12 |
|
Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion. Enolase superfamily contains different enzymes, like enolases, glutarate-, fucanate- and galactonate dehydratases, o-succinylbenzoate synthase, N-acylamino acid racemase, L-alanine-DL-glutamate epimerase, mandelate racemase, muconate lactonizing enzyme and 3-methylaspartase.
Pssm-ID: 238188 [Multi-domain] Cd Length: 229 Bit Score: 65.04 E-value: 5.77e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 284 VNKYPIITIEDGMDENDWDGWKVLTERLGkrVQLVGDDFFVTNtEYLARGIKENAANSILIKVNQIGTLTETFEAIEMAK 363
Cdd:cd00308 117 LEKYGLAWIEEPCAPDDLEGYAALRRRTG--IPIAADESVTTV-DDALEALELGAVDILQIKPTRVGGLTESRRAADLAE 193
|
90 100 110
....*....|....*....|....*....|....*.
8DG4_E 364 EAGYTAVVSHRSG-ETEDSTIADIAVAT-NAGQIKT 397
Cdd:cd00308 194 AFGIRVMVHGTLEsSIGTAAALHLAAALpNDRAIET 229
|
|
| PTZ00378 |
PTZ00378 |
hypothetical protein; Provisional |
86-419 |
2.45e-09 |
|
hypothetical protein; Provisional
Pssm-ID: 173571 [Multi-domain] Cd Length: 518 Bit Score: 59.12 E-value: 2.45e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 86 RDQQAIDRAMIALDGTPNKGKLGANAILGVSIAVARAAADYLEVPLYTYL-------GGFNTKVLPTPMMNIINGGSHSD 158
Cdd:PTZ00378 125 RDQREFDSTLRAALSTSPLANVGSAVQWALSIVASLAAARCRSVPLFQYLralfgslTSVETFSMPQLCITFFGPGNPST 204
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 159 APIAFQEFMIMPV---GApTFKEGLRwgaEVFHALKKILKERGlvTAVGDEGGFA-PKFEGTEDGVETILKAIEAAGYEA 234
Cdd:PTZ00378 205 ARLALKSVLFSPVmpsGT-VLRERMQ---KIFAAFHHFCQSHN--SSVRSDGSLHwDGFANLTDAVKLATEALRAVQLTP 278
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 235 GENgIMIGFDCASSEFYDAERAVYD--------------YTKFEGEgaAVRTSAEQVDYLEELVNKYP--IITIEDGMDE 298
Cdd:PTZ00378 279 GTD-VCLGLRMAASTTRVPATAVADggawkeakddcevlYSLFPGE--PDVTGDQLSEYVREQLQAVPdiVVYVEDTHCD 355
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 299 NDWDGWKVLTERLGKRVQLVGDDFFvTNTEY--LARGIKENAANSILIKVNQIGTLTETFEAIEMAKE-AGYTAVVSHRS 375
Cdd:PTZ00378 356 EDTFGLQRLQAALGDSIVLSGVDVY-ARSEYkkVESGLRGLWTSNIVLNPCAIGTLSDVVEIVRAVGEdEGRAVTVLVQT 434
|
330 340 350 360
....*....|....*....|....*....|....*....|....
8DG4_E 376 GETEDSTIADIAVATNAGQIKTGSLSRTDRIAKYNQLLRIEDQL 419
Cdd:PTZ00378 435 LAGNAATAAHLAVAMGARFLCSGGLFSAHQCEVVSQLASRQDEL 478
|
|
| RspA |
COG4948 |
L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily [Cell wall/membrane ... |
24-392 |
1.06e-06 |
|
L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily [Cell wall/membrane/envelope biogenesis, General function prediction only]; L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway
Pssm-ID: 443975 [Multi-domain] Cd Length: 359 Bit Score: 50.59 E-value: 1.06e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 24 VEVYTESGAFGRGMVPSGastgeheavelrdgdksrylGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN 103
Cdd:COG4948 34 VRVETDDGITGWGEAVPG--------------------GTGAEAVAAALEEALAPLLIGRDPLDIEALWQRLYRALPGNP 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 104 kgklgaNAILGVSIAVARAAADYLEVPLYTYLGGFNTKVLPTpmmniinGGSHSDAPIafqEFMImpvgaptfKEGLRWG 183
Cdd:COG4948 94 ------AAKAAVDMALWDLLGKALGVPVYQLLGGKVRDRVPV-------YATLGIDTP---EEMA--------EEAREAV 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 184 AEVFHALKkiLKerglvtaVGDEGGfapkfegtEDGVEtILKAI-EAAGYEAgenGIMIGFDCAssefYDAERAvydytk 262
Cdd:COG4948 150 ARGFRALK--LK-------VGGPDP--------EEDVE-RVRAVrEAVGPDA---RLRVDANGA----WTLEEA------ 198
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 263 fegegaavrtsaeqVDYLEELVnKYPIITIEDGMDENDWDGWKVLTERLgkRVQLVGDDFFVTNTEyLARGIKENAANSI 342
Cdd:COG4948 199 --------------IRLLRALE-DLGLEWIEQPLPAEDLEGLAELRRAT--PVPIAADESLTSRAD-FRRLIEAGAVDIV 260
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|
8DG4_E 343 LIKVNQIGTLTETFEAIEMAKEAGyTAVVSHRSGETedstiaDIAVATNA 392
Cdd:COG4948 261 NIKLSKVGGLTEALRIAALAEAHG-VPVMPHCMLES------GIGLAAAL 303
|
|
| NAAAR |
cd03317 |
N-acylamino acid racemase (NAAAR), an octameric enzyme that catalyzes the racemization of ... |
275-405 |
6.36e-03 |
|
N-acylamino acid racemase (NAAAR), an octameric enzyme that catalyzes the racemization of N-acylamino acids. NAAARs act on a broad range of N-acylamino acids rather than amino acids. Enantiopure amino acids are of industrial interest as chiral building blocks for antibiotics, herbicides, and drugs. NAAAR is a member of the enolase superfamily, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion.
Pssm-ID: 239433 [Multi-domain] Cd Length: 354 Bit Score: 38.37 E-value: 6.36e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8DG4_E 275 EQVDYLEELvNKYPIITIEDGMDENDWDGWKVLTERLGKRVQLvgdDFFVTNTEYLARGIKENAANSILIKVNQIGTLTE 354
Cdd:cd03317 192 ADIPLLKRL-DEYGLLMIEQPLAADDLIDHAELQKLLKTPICL---DESIQSAEDARKAIELGACKIINIKPGRVGGLTE 267
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
8DG4_E 355 TFEAIEMAKEAGYTAVVshrsG---ETEDSTIADIAVATNAGQIKTGSLSRTDR 405
Cdd:cd03317 268 ALKIHDLCQEHGIPVWC----GgmlESGIGRAHNVALASLPNFTYPGDISASSR 317
|
|
| |
