|
Name |
Accession |
Description |
Interval |
E-value |
| LolD |
COG1136 |
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis]; |
11-228 |
6.62e-117 |
|
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440751 [Multi-domain] Cd Length: 227 Bit Score: 333.93 E-value: 6.62e-117
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 11 ILEANKIRKSYGNKLNKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLAEF 90
Cdd:COG1136 4 LLELRNLTKSYGTGEGEVTALRGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVLIDGQDISSLSERELARL 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 91 RKQHLGFIFQDYNLLDTLTVKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDP 170
Cdd:COG1136 84 RRRHIGFVFQFFNLLPELTALENVALPLLLAGVSRKERRERARELLERVGLGDRLDHRPSQLSGGQQQRVAIARALVNRP 163
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
8G4D_C 171 SIIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHDPVAASYCGRVIFIKDGQ 228
Cdd:COG1136 164 KLILADEPTGNLDSKTGEEVLELLRELNRELGTTIVMVTHDPELAARADRVIRLRDGR 221
|
|
| ABC_MJ0796_LolCDE_FtsE |
cd03255 |
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ... |
12-228 |
8.00e-108 |
|
ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.
Pssm-ID: 213222 [Multi-domain] Cd Length: 218 Bit Score: 310.58 E-value: 8.00e-108
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 12 LEANKIRKSYGNKLNKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLAEFR 91
Cdd:cd03255 1 IELKNLSKTYGGGGEKVQALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDGTDISKLSEKELAAFR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 92 KQHLGFIFQDYNLLDTLTVKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPS 171
Cdd:cd03255 81 RRHIGFVFQSFNLLPDLTALENVELPLLLAGVPKKERRERAEELLERVGLGDRLNHYPSELSGGQQQRVAIARALANDPK 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
8G4D_C 172 IIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHDPVAASYCGRVIFIKDGQ 228
Cdd:cd03255 161 IILADEPTGNLDSETGKEVMELLRELNKEAGTTIVVVTHDPELAEYADRIIELRDGK 217
|
|
| FtsE |
COG2884 |
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning]; |
19-229 |
5.34e-74 |
|
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442130 [Multi-domain] Cd Length: 223 Bit Score: 224.93 E-value: 5.34e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 19 KSYGNKlnkQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLAEFRkQHLGFI 98
Cdd:COG2884 9 KRYPGG---REALSDVSLEIEKGEFVFLTGPSGAGKSTLLKLLYGEERPTSGQVLVNGQDLSRLKRREIPYLR-RRIGVV 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 99 FQDYNLLDTLTVKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPSIIFADEP 178
Cdd:COG2884 85 FQDFRLLPDRTVYENVALPLRVTGKSRKEIRRRVREVLDLVGLSDKAKALPHELSGGEQQRVAIARALVNRPELLLADEP 164
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
8G4D_C 179 TGALDSKSASDLLNKLSQLNQkRNATIIMVTHDP-VAASYCGRVIFIKDGQM 229
Cdd:COG2884 165 TGNLDPETSWEIMELLEEINR-RGTTVLIATHDLeLVDRMPKRVLELEDGRL 215
|
|
| YbbA |
COG4181 |
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ... |
11-229 |
5.28e-72 |
|
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443338 [Multi-domain] Cd Length: 233 Bit Score: 220.00 E-value: 5.28e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 11 ILEANKIRKSYGNKLNKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLAEF 90
Cdd:COG4181 8 IIELRGLTKTVGTGAGELTILKGISLEVEAGESVAIVGASGSGKSTLLGLLAGLDRPTSGTVRLAGQDLFALDEDARARL 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 91 RKQHLGFIFQDYNLLDTLTVKENILLPLSITklSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDP 170
Cdd:COG4181 88 RARHVGFVFQSFQLLPTLTALENVMLPLELA--GRRDARARARALLERVGLGHRLDHYPAQLSGGEQQRVALARAFATEP 165
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
8G4D_C 171 SIIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHDPVAASYCGRVIFIKDGQM 229
Cdd:COG4181 166 AILFADEPTGNLDAATGEQIIDLLFELNRERGTTLVLVTHDPALAARCDRVLRLRAGRL 224
|
|
| L_ocin_972_ABC |
TIGR03608 |
putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly ... |
17-224 |
1.18e-69 |
|
putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly wide distribution consists of a polypeptide related to the lactococcin 972 (see TIGR01653) and multiple-membrane-spanning putative immunity protein (see TIGR01654). This model represents a small clade within the ABC transporters that regularly are found adjacent to these bacteriocin system gene pairs and are likely serve as export proteins. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 188353 [Multi-domain] Cd Length: 206 Bit Score: 213.25 E-value: 1.18e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 17 IRKSYGNKlnkqEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLAEFRKQHLG 96
Cdd:TIGR03608 4 ISKKFGDK----VILDDLNLTIEKGKMYAIIGESGSGKSTLLNIIGLLEKFDSGQVYLNGQETPPLNSKKASKFRREKLG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 97 FIFQDYNLLDTLTVKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPSIIFAD 176
Cdd:TIGR03608 80 YLFQNFALIENETVEENLDLGLKYKKLSKKEKREKKKEALEKVGLNLKLKQKIYELSGGEQQRVALARAILKPPPLILAD 159
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
8G4D_C 177 EPTGALDSKSASDLLNKLSQLNqKRNATIIMVTHDPVAASYCGRVIFI 224
Cdd:TIGR03608 160 EPTGSLDPKNRDEVLDLLLELN-DEGKTIIIVTHDPEVAKQADRVIEL 206
|
|
| LolD_lipo_ex |
TIGR02211 |
lipoprotein releasing system, ATP-binding protein; This model represents LolD, a member of the ... |
11-230 |
3.83e-67 |
|
lipoprotein releasing system, ATP-binding protein; This model represents LolD, a member of the ABC transporter family (pfam00005). LolD is involved in localization of lipoproteins in some bacteria. It works with a transmembrane protein LolC, which in some species is a paralogous pair LolC and LolE. Depending on whether the residue immediately following the new, modified N-terminal Cys residue, the nascent lipoprotein may be carried further by LolA and LolB to the outer membrane, or remain at the inner membrane. The top scoring proteins excluded by this model include homologs from the archaeal genus Methanosarcina. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 131266 [Multi-domain] Cd Length: 221 Bit Score: 207.59 E-value: 3.83e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 11 ILEANKIRKSYGNKLNKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLAEF 90
Cdd:TIGR02211 1 LLKCENLGKRYQEGKLDTRVLKGVSLSIGKGEIVAIVGSSGSGKSTLLHLLGGLDNPTSGEVLFNGQSLSKLSSNERAKL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 91 RKQHLGFIFQDYNLLDTLTVKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDP 170
Cdd:TIGR02211 81 RNKKLGFIYQFHHLLPDFTALENVAMPLLIGKKSVKEAKERAYEMLEKVGLEHRINHRPSELSGGERQRVAIARALVNQP 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 171 SIIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHDPVAASYCGRVIFIKDGQMY 230
Cdd:TIGR02211 161 SLVLADEPTGNLDNNNAKIIFDLMLELNRELNTSFLVVTHDLELAKKLDRVLEMKDGQLF 220
|
|
| ABC_MetN_methionine_transporter |
cd03258 |
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ... |
11-228 |
2.08e-66 |
|
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213225 [Multi-domain] Cd Length: 233 Bit Score: 205.89 E-value: 2.08e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 11 ILEANKIRKSYGNKLNKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLAEF 90
Cdd:cd03258 1 MIELKNVSKVFGDTGGKVTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLVDGTDLTLLSGKELRKA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 91 RkQHLGFIFQDYNLLDTLTVKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDP 170
Cdd:cd03258 81 R-RRIGMIFQHFNLLSSRTVFENVALPLEIAGVPKAEIEERVLELLELVGLEDKADAYPAQLSGGQKQRVGIARALANNP 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
8G4D_C 171 SIIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHD-PVAASYCGRVIFIKDGQ 228
Cdd:cd03258 160 KVLLCDEATSALDPETTQSILALLRDINRELGLTIVLITHEmEVVKRICDRVAVMEKGE 218
|
|
| ABC_NrtD_SsuB_transporters |
cd03293 |
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ... |
12-211 |
1.45e-65 |
|
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213260 [Multi-domain] Cd Length: 220 Bit Score: 203.47 E-value: 1.45e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 12 LEANKIRKSYGNKLNKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGndmtamkeKQLAEFR 91
Cdd:cd03293 1 LEVRNVSKTYGGGGGAVTALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLVDG--------EPVTGPG 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 92 KqHLGFIFQDYNLLDTLTVKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPS 171
Cdd:cd03293 73 P-DRGYVFQQDALLPWLTVLDNVALGLELQGVPKAEARERAEELLELVGLSGFENAYPHQLSGGMRQRVALARALAVDPD 151
|
170 180 190 200
....*....|....*....|....*....|....*....|
8G4D_C 172 IIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHD 211
Cdd:cd03293 152 VLLLDEPFSALDALTREQLQEELLDIWRETGKTVLLVTHD 191
|
|
| MalK |
COG3839 |
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ... |
12-229 |
1.75e-64 |
|
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];
Pssm-ID: 443050 [Multi-domain] Cd Length: 352 Bit Score: 204.92 E-value: 1.75e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 12 LEANKIRKSYGNKlnkqEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQlaefR 91
Cdd:COG3839 4 LELENVSKSYGGV----EALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPTSGEILIGGRDVTDLPPKD----R 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 92 kqHLGFIFQDYNLLDTLTVKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPS 171
Cdd:COG3839 76 --NIAMVFQSYALYPHMTVYENIAFPLKLRKVPKAEIDRRVREAAELLGLEDLLDRKPKQLSGGQRQRVALGRALVREPK 153
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
8G4D_C 172 IIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHDPV-AASYCGRVIFIKDGQM 229
Cdd:COG3839 154 VFLLDEPLSNLDAKLRVEMRAEIKRLHRRLGTTTIYVTHDQVeAMTLADRIAVMNDGRI 212
|
|
| TauB |
COG1116 |
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ... |
10-211 |
2.12e-64 |
|
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440733 [Multi-domain] Cd Length: 260 Bit Score: 201.86 E-value: 2.12e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 10 VILEANKIRKSYGNKLNKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAmkekqlae 89
Cdd:COG1116 6 PALELRGVSKRFPTGGGGVTALDDVSLTVAAGEFVALVGPSGCGKSTLLRLIAGLEKPTSGEVLVDGKPVTG-------- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 90 fRKQHLGFIFQDYNLLDTLTVKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHD 169
Cdd:COG1116 78 -PGPDRGVVFQEPALLPWLTVLDNVALGLELRGVPKAERRERARELLELVGLAGFEDAYPHQLSGGMRQRVAIARALAND 156
|
170 180 190 200
....*....|....*....|....*....|....*....|..
8G4D_C 170 PSIIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHD 211
Cdd:COG1116 157 PEVLLMDEPFGALDALTRERLQDELLRLWQETGKTVLFVTHD 198
|
|
| ABC_Carb_Solutes_like |
cd03259 |
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ... |
12-228 |
4.25e-63 |
|
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213226 [Multi-domain] Cd Length: 213 Bit Score: 196.97 E-value: 4.25e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 12 LEANKIRKSYGnklnKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEkqlaefR 91
Cdd:cd03259 1 LELKGLSKTYG----SVRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILIDGRDVTGVPP------E 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 92 KQHLGFIFQDYNLLDTLTVKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPS 171
Cdd:cd03259 71 RRNIGMVFQDYALFPHLTVAENIAFGLKLRGVPKAEIRARVRELLELVGLEGLLNRYPHELSGGQQQRVALARALAREPS 150
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
8G4D_C 172 IIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHDPV-AASYCGRVIFIKDGQ 228
Cdd:cd03259 151 LLLLDEPLSALDAKLREELREELKELQRELGITTIYVTHDQEeALALADRIAVMNEGR 208
|
|
| AbcC |
COG1135 |
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism]; |
17-228 |
2.78e-62 |
|
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440750 [Multi-domain] Cd Length: 339 Bit Score: 198.76 E-value: 2.78e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 17 IRKSYGNKLNKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLAEFRKQhLG 96
Cdd:COG1135 7 LSKTFPTKGGPVTALDDVSLTIEKGEIFGIIGYSGAGKSTLIRCINLLERPTSGSVLVDGVDLTALSERELRAARRK-IG 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 97 FIFQDYNLLDTLTVKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPSIIFAD 176
Cdd:COG1135 86 MIFQHFNLLSSRTVAENVALPLEIAGVPKAEIRKRVAELLELVGLSDKADAYPSQLSGGQKQRVGIARALANNPKVLLCD 165
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
8G4D_C 177 EPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHD-PVAASYCGRVIFIKDGQ 228
Cdd:COG1135 166 EATSALDPETTRSILDLLKDINRELGLTIVLITHEmDVVRRICDRVAVLENGR 218
|
|
| MlaF |
COG1127 |
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ... |
10-229 |
7.39e-62 |
|
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440744 [Multi-domain] Cd Length: 241 Bit Score: 194.43 E-value: 7.39e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 10 VILEANKIRKSYGNKlnkqEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLAE 89
Cdd:COG1127 4 PMIEVRNLTKSFGDR----VVLDGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSGEILVDGQDITGLSEKELYE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 90 FRKQhLGFIFQDYNLLDTLTVKENILLPLSI-TKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIH 168
Cdd:COG1127 80 LRRR-IGMLFQGGALFDSLTVFENVAFPLREhTDLSEAEIRELVLEKLELVGLPGAADKMPSELSGGMRKRVALARALAL 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
8G4D_C 169 DPSIIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHD-PVAASYCGRVIFIKDGQM 229
Cdd:COG1127 159 DPEILLYDEPTAGLDPITSAVIDELIRELRDELGLTSVVVTHDlDSAFAIADRVAVLADGKI 220
|
|
| PRK10535 |
PRK10535 |
macrolide ABC transporter ATP-binding protein/permease MacB; |
11-229 |
2.66e-61 |
|
macrolide ABC transporter ATP-binding protein/permease MacB;
Pssm-ID: 182528 [Multi-domain] Cd Length: 648 Bit Score: 203.80 E-value: 2.66e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 11 ILEANKIRKSYGNKLNKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLAEF 90
Cdd:PRK10535 4 LLELKDIRRSYPSGEEQVEVLKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSGTYRVAGQDVATLDADALAQL 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 91 RKQHLGFIFQDYNLLDTLTVKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDP 170
Cdd:PRK10535 84 RREHFGFIFQRYHLLSHLTAAQNVEVPAVYAGLERKQRLLRAQELLQRLGLEDRVEYQPSQLSGGQQQRVSIARALMNGG 163
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
8G4D_C 171 SIIFADEPTGALDSKSASDLLNKLSQLNQkRNATIIMVTHDPVAASYCGRVIFIKDGQM 229
Cdd:PRK10535 164 QVILADEPTGALDSHSGEEVMAILHQLRD-RGHTVIIVTHDPQVAAQAERVIEIRDGEI 221
|
|
| ABC_NikE_OppD_transporters |
cd03257 |
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ... |
11-229 |
2.52e-60 |
|
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.
Pssm-ID: 213224 [Multi-domain] Cd Length: 228 Bit Score: 190.41 E-value: 2.52e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 11 ILEANKIRKSYGNKLNKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLAEF 90
Cdd:cd03257 1 LLEVKNLSVSFPTGGGSVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFDGKDLLKLSRRLRKIR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 91 RKqHLGFIFQD-YNLLD-TLTVKENILLPLSI-TKLSKKEANRKFE-EVAKELGIYELR-DKYPNEISGGQKQRTSAGRA 165
Cdd:cd03257 81 RK-EIQMVFQDpMSSLNpRMTIGEQIAEPLRIhGKLSKKEARKEAVlLLLVGVGLPEEVlNRYPHELSGGQRQRVAIARA 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
8G4D_C 166 FIHDPSIIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHD-PVAASYCGRVIFIKDGQM 229
Cdd:cd03257 160 LALNPKLLIADEPTSALDVSVQAQILDLLKKLQEELGLTLLFITHDlGVVAKIADRVAVMYAGKI 224
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
10-228 |
1.63e-59 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 196.28 E-value: 1.63e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 10 VILEANKIRKSYG-NKLNKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLA 88
Cdd:COG1123 259 PLLEVRNLSKRYPvRGKGGVRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRPTSGSILFDGKDLTKLSRRSLR 338
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 89 EFRKqHLGFIFQD-YNLLD-TLTVKENILLPLSI-TKLSKKEANRKFEEVAKELGI-YELRDKYPNEISGGQKQRTSAGR 164
Cdd:COG1123 339 ELRR-RVQMVFQDpYSSLNpRMTVGDIIAEPLRLhGLLSRAERRERVAELLERVGLpPDLADRYPHELSGGQRQRVAIAR 417
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
8G4D_C 165 AFIHDPSIIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHD-PVAASYCGRVIFIKDGQ 228
Cdd:COG1123 418 ALALEPKLLILDEPTSALDVSVQAQILNLLRDLQRELGLTYLFISHDlAVVRYIADRVAVMYDGR 482
|
|
| PhnC |
COG3638 |
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and ... |
11-229 |
4.22e-59 |
|
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 442855 [Multi-domain] Cd Length: 249 Bit Score: 187.96 E-value: 4.22e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 11 ILEANKIRKSYGNKlnkQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLAEF 90
Cdd:COG3638 2 MLELRNLSKRYPGG---TPALDDVSLEIERGEFVALIGPSGAGKSTLLRCLNGLVEPTSGEILVDGQDVTALRGRALRRL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 91 RKQhLGFIFQDYNLLDTLTVKENIL--------LPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSA 162
Cdd:COG3638 79 RRR-IGMIFQQFNLVPRLSVLTNVLagrlgrtsTWRSLLGLFPPEDRERALEALERVGLADKAYQRADQLSGGQQQRVAI 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
8G4D_C 163 GRAFIHDPSIIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHDP-VAASYCGRVIFIKDGQM 229
Cdd:COG3638 158 ARALVQEPKLILADEPVASLDPKTARQVMDLLRRIAREDGITVVVNLHQVdLARRYADRIIGLRDGRV 225
|
|
| FepC |
COG1120 |
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ... |
11-232 |
3.33e-58 |
|
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];
Pssm-ID: 440737 [Multi-domain] Cd Length: 254 Bit Score: 185.63 E-value: 3.33e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 11 ILEANKIRKSYGNKlnkqEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLAef 90
Cdd:COG1120 1 MLEAENLSVGYGGR----PVLDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLLDGRDLASLSRRELA-- 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 91 rkQHLGFIFQDYNLLDTLTVKENILL---P-LSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAF 166
Cdd:COG1120 75 --RRIAYVPQEPPAPFGLTVRELVALgryPhLGLFGRPSAEDREAVEEALERTGLEHLADRPVDELSGGERQRVLIARAL 152
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
8G4D_C 167 IHDPSIIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHDP-VAASYCGRVIFIKDGQMYTQ 232
Cdd:COG1120 153 AQEPPLLLLDEPTSHLDLAHQLEVLELLRRLARERGRTVVMVLHDLnLAARYADRLVLLKDGRIVAQ 219
|
|
| CcmA |
COG1131 |
ABC-type multidrug transport system, ATPase component [Defense mechanisms]; |
12-229 |
5.97e-58 |
|
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
Pssm-ID: 440746 [Multi-domain] Cd Length: 236 Bit Score: 184.50 E-value: 5.97e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 12 LEANKIRKSYGNKlnkqEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTamkeKQLAEFR 91
Cdd:COG1131 1 IEVRGLTKRYGDK----TALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVLGEDVA----RDPAEVR 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 92 kQHLGFIFQDYNLLDTLTVKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPS 171
Cdd:COG1131 73 -RRIGYVPQEPALYPDLTVRENLRFFARLYGLPRKEARERIDELLELFGLTDAADRKVGTLSGGMKQRLGLALALLHDPE 151
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
8G4D_C 172 IIFADEPTGALDSKSASDLLNKLSQLNqKRNATIIMVTHD-PVAASYCGRVIFIKDGQM 229
Cdd:COG1131 152 LLILDEPTSGLDPEARRELWELLRELA-AEGKTVLLSTHYlEEAERLCDRVAIIDKGRI 209
|
|
| DppF |
COG1124 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
12-229 |
1.44e-57 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440741 [Multi-domain] Cd Length: 248 Bit Score: 183.85 E-value: 1.44e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 12 LEANKIRKSYGNKLNKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGndmTAMKEKQLAEFR 91
Cdd:COG1124 2 LEVRNLSVSYGQGGRRVPVLKDVSLEVAPGESFGLVGESGSGKSTLLRALAGLERPWSGEVTFDG---RPVTRRRRKAFR 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 92 KQhLGFIFQD-YNLLD-TLTVKENILLPLSITKLskKEANRKFEEVAKELGIY-ELRDKYPNEISGGQKQRTSAGRAFIH 168
Cdd:COG1124 79 RR-VQMVFQDpYASLHpRHTVDRILAEPLRIHGL--PDREERIAELLEQVGLPpSFLDRYPHQLSGGQRQRVAIARALIL 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
8G4D_C 169 DPSIIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHDPVAASY-CGRVIFIKDGQM 229
Cdd:COG1124 156 EPELLLLDEPTSALDVSVQAEILNLLKDLREERGLTYLFVSHDLAVVAHlCDRVAVMQNGRI 217
|
|
| PotA |
COG3842 |
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ... |
11-228 |
2.34e-57 |
|
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443052 [Multi-domain] Cd Length: 353 Bit Score: 186.46 E-value: 2.34e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 11 ILEANKIRKSYGNklnkQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKekqlAEF 90
Cdd:COG3842 5 ALELENVSKRYGD----VTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDVTGLP----PEK 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 91 RkqHLGFIFQDYNLLDTLTVKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDP 170
Cdd:COG3842 77 R--NVGMVFQDYALFPHLTVAENVAFGLRMRGVPKAEIRARVAELLELVGLEGLADRYPHQLSGGQQQRVALARALAPEP 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
8G4D_C 171 SIIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHDPV-AASYCGRVIFIKDGQ 228
Cdd:COG3842 155 RVLLLDEPLSALDAKLREEMREELRRLQRELGITFIYVTHDQEeALALADRIAVMNDGR 213
|
|
| heterocyst_DevA |
TIGR02982 |
ABC exporter ATP-binding subunit, DevA family; Members of this protein family are found mostly ... |
21-229 |
6.07e-56 |
|
ABC exporter ATP-binding subunit, DevA family; Members of this protein family are found mostly in the Cyanobacteria, but also in the Planctomycetes. Cyanobacterial examples are involved in heterocyst formation, by which some fraction of members of the colony undergo a developmental change and become capable of nitrogen fixation. The DevBCA proteins are thought export of either heterocyst-specific glycolipids or an enzyme essential for formation of the laminated layer found in heterocysts.
Pssm-ID: 274374 [Multi-domain] Cd Length: 220 Bit Score: 178.67 E-value: 6.07e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 21 YGNKLNKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLAEFRKQhLGFIFQ 100
Cdd:TIGR02982 11 YGHGSLRKQVLFDINLEINPGEIVILTGPSGSGKTTLLTLIGGLRSVQEGSLKVLGQELHGASKKQLVQLRRR-IGYIFQ 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 101 DYNLLDTLTVKENILLPLSI-TKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPSIIFADEPT 179
Cdd:TIGR02982 90 AHNLLGFLTARQNVQMALELqPNLSYQEARERARAMLEAVGLGDHLNYYPHNLSGGQKQRVAIARALVHHPKLVLADEPT 169
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
8G4D_C 180 GALDSKSASDLLNKLSQLNQKRNATIIMVTHDPVAASYCGRVIFIKDGQM 229
Cdd:TIGR02982 170 AALDSKSGRDVVELMQKLAKEQGCTILMVTHDNRILDVADRILQMEDGKL 219
|
|
| ABC_cobalt_CbiO_domain1 |
cd03225 |
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ... |
13-228 |
3.20e-55 |
|
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213192 [Multi-domain] Cd Length: 211 Bit Score: 176.50 E-value: 3.20e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 13 EANKIRKSYGNKlnKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLAefrk 92
Cdd:cd03225 1 ELKNLSFSYPDG--ARPALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDGKDLTKLSLKELR---- 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 93 QHLGFIFQDYNL-LDTLTVKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPS 171
Cdd:cd03225 75 RKVGLVFQNPDDqFFGPTVEEEVAFGLENLGLPEEEIEERVEEALELVGLEGLRDRSPFTLSGGQKQRVAIAGVLAMDPD 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
8G4D_C 172 IIFADEPTGALDSKSASDLLNKLSQLNQKrNATIIMVTHDP-VAASYCGRVIFIKDGQ 228
Cdd:cd03225 155 ILLLDEPTAGLDPAGRRELLELLKKLKAE-GKTIIIVTHDLdLLLELADRVIVLEDGK 211
|
|
| ABC_MalK_N |
cd03301 |
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ... |
10-228 |
6.51e-55 |
|
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.
Pssm-ID: 213268 [Multi-domain] Cd Length: 213 Bit Score: 175.91 E-value: 6.51e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 10 VILEanKIRKSYGNKlnkqEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKqlae 89
Cdd:cd03301 1 VELE--NVTKRFGNV----TALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYIGGRDVTDLPPK---- 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 90 frKQHLGFIFQDYNLLDTLTVKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHD 169
Cdd:cd03301 71 --DRDIAMVFQNYALYPHMTVYDNIAFGLKLRKVPKDEIDERVREVAELLQIEHLLDRKPKQLSGGQRQRVALGRAIVRE 148
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 170 PSIIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHDPVAASYCG-RVIFIKDGQ 228
Cdd:cd03301 149 PKVFLMDEPLSNLDAKLRVQMRAELKRLQQRLGTTTIYVTHDQVEAMTMAdRIAVMNDGQ 208
|
|
| ABC_PhnC_transporter |
cd03256 |
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ... |
12-228 |
7.27e-55 |
|
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213223 [Multi-domain] Cd Length: 241 Bit Score: 176.60 E-value: 7.27e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 12 LEANKIRKSYGNKlnkQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLAEFR 91
Cdd:cd03256 1 IEVENLSKTYPNG---KKALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIDGTDINKLKGKALRQLR 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 92 KqHLGFIFQDYNLLDTLTVKENILLPL--------SITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAG 163
Cdd:cd03256 78 R-QIGMIFQQFNLIERLSVLENVLSGRlgrrstwrSLFGLFPKEEKQRALAALERVGLLDKAYQRADQLSGGQQQRVAIA 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
8G4D_C 164 RAFIHDPSIIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHDP-VAASYCGRVIFIKDGQ 228
Cdd:cd03256 157 RALMQQPKLILADEPVASLDPASSRQVMDLLKRINREEGITVIVSLHQVdLAREYADRIVGLKDGR 222
|
|
| PRK10584 |
PRK10584 |
putative ABC transporter ATP-binding protein YbbA; Provisional |
11-229 |
1.78e-54 |
|
putative ABC transporter ATP-binding protein YbbA; Provisional
Pssm-ID: 182569 [Multi-domain] Cd Length: 228 Bit Score: 175.35 E-value: 1.78e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 11 ILEANKIRKSYGNKLNKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLAEF 90
Cdd:PRK10584 6 IVEVHHLKKSVGQGEHELSILTGVELVVKRGETIALIGESGSGKSTLLAILAGLDDGSSGEVSLVGQPLHQMDEEARAKL 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 91 RKQHLGFIFQDYNLLDTLTVKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDP 170
Cdd:PRK10584 86 RAKHVGFVFQSFMLIPTLNALENVELPALLRGESSRQSRNGAKALLEQLGLGKRLDHLPAQLSGGEQQRVALARAFNGRP 165
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
8G4D_C 171 SIIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHDPVAASYCGRVIFIKDGQM 229
Cdd:PRK10584 166 DVLFADEPTGNLDRQTGDKIADLLFSLNREHGTTLILVTHDLQLAARCDRRLRLVNGQL 224
|
|
| ABC_HisP_GlnQ |
cd03262 |
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ... |
12-228 |
2.36e-54 |
|
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.
Pssm-ID: 213229 [Multi-domain] Cd Length: 213 Bit Score: 174.64 E-value: 2.36e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 12 LEANKIRKSYGNKlnkqEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAmKEKQLAEFR 91
Cdd:cd03262 1 IEIKNLHKSFGDF----HVLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIIDGLKLTD-DKKNINELR 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 92 kQHLGFIFQDYNLLDTLTVKENILL-PLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDP 170
Cdd:cd03262 76 -QKVGMVFQQFNLFPHLTVLENITLaPIKVKGMSKAEAEERALELLEKVGLADKADAYPAQLSGGQQQRVAIARALAMNP 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
8G4D_C 171 SIIFADEPTGALDSKSASDLLNKLSQLNQKrNATIIMVTHD-PVAASYCGRVIFIKDGQ 228
Cdd:cd03262 155 KVMLFDEPTSALDPELVGEVLDVMKDLAEE-GMTMVVVTHEmGFAREVADRVIFMDDGR 212
|
|
| EcfA2 |
COG1122 |
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ... |
12-229 |
6.26e-54 |
|
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];
Pssm-ID: 440739 [Multi-domain] Cd Length: 230 Bit Score: 174.06 E-value: 6.26e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 12 LEANKIRKSYGNKlnkQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTamkEKQLAEFR 91
Cdd:COG1122 1 IELENLSFSYPGG---TPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVDGKDIT---KKNLRELR 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 92 kQHLGFIFQDYN--LLDTlTVKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTS-AGrAFIH 168
Cdd:COG1122 75 -RKVGLVFQNPDdqLFAP-TVEEDVAFGPENLGLPREEIRERVEEALELVGLEHLADRPPHELSGGQKQRVAiAG-VLAM 151
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
8G4D_C 169 DPSIIFADEPTGALDSKSASDLLNKLSQLNQkRNATIIMVTHDP-VAASYCGRVIFIKDGQM 229
Cdd:COG1122 152 EPEVLVLDEPTAGLDPRGRRELLELLKRLNK-EGKTVIIVTHDLdLVAELADRVIVLDDGRI 212
|
|
| ABC_FtsE |
cd03292 |
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ... |
12-229 |
8.76e-54 |
|
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages
Pssm-ID: 213259 [Multi-domain] Cd Length: 214 Bit Score: 172.98 E-value: 8.76e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 12 LEANKIRKSYGNKLnkqEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLAEFR 91
Cdd:cd03292 1 IEFINVTKTYPNGT---AALDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVNGQDVSDLRGRAIPYLR 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 92 kQHLGFIFQDYNLLDTLTVKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPS 171
Cdd:cd03292 78 -RKIGVVFQDFRLLPDRNVYENVAFALEVTGVPPREIRKRVPAALELVGLSHKHRALPAELSGGEQQRVAIARAIVNSPT 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
8G4D_C 172 IIFADEPTGALDSKSASDLLNKLSQLNqKRNATIIMVTHDP-VAASYCGRVIFIKDGQM 229
Cdd:cd03292 157 ILIADEPTGNLDPDTTWEIMNLLKKIN-KAGTTVVVATHAKeLVDTTRHRVIALERGKL 214
|
|
| ABC_Org_Solvent_Resistant |
cd03261 |
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ... |
12-228 |
2.90e-53 |
|
ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213228 [Multi-domain] Cd Length: 235 Bit Score: 172.30 E-value: 2.90e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 12 LEANKIRKSYGNKlnkqEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLAEFR 91
Cdd:cd03261 1 IELRGLTKSFGGR----TVLKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDGEDISGLSEAELYRLR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 92 KQhLGFIFQDYNLLDTLTVKENILLPLSI-TKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDP 170
Cdd:cd03261 77 RR-MGMLFQSGALFDSLTVFENVAFPLREhTRLSEEEIREIVLEKLEAVGLRGAEDLYPAELSGGMKKRVALARALALDP 155
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
8G4D_C 171 SIIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHD-PVAASYCGRVIFIKDGQ 228
Cdd:cd03261 156 ELLLYDEPTAGLDPIASGVIDDLIRSLKKELGLTSIMVTHDlDTAFAIADRIAVLYDGK 214
|
|
| metN |
PRK11153 |
DL-methionine transporter ATP-binding subunit; Provisional |
13-229 |
8.94e-53 |
|
DL-methionine transporter ATP-binding subunit; Provisional
Pssm-ID: 236863 [Multi-domain] Cd Length: 343 Bit Score: 174.60 E-value: 8.94e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 13 EANKIRKSYGNKLNKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLAEFRk 92
Cdd:PRK11153 3 ELKNISKVFPQGGRTIHALNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGRVLVDGQDLTALSEKELRKAR- 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 93 QHLGFIFQDYNLLDTLTVKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPSI 172
Cdd:PRK11153 82 RQIGMIFQHFNLLSSRTVFDNVALPLELAGTPKAEIKARVTELLELVGLSDKADRYPAQLSGGQKQRVAIARALASNPKV 161
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
8G4D_C 173 IFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHD-PVAASYCGRVIFIKDGQM 229
Cdd:PRK11153 162 LLCDEATSALDPATTRSILELLKDINRELGLTIVLITHEmDVVKRICDRVAVIDAGRL 219
|
|
| ABC_PotA_N |
cd03300 |
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ... |
17-211 |
5.75e-52 |
|
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213267 [Multi-domain] Cd Length: 232 Bit Score: 168.95 E-value: 5.75e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 17 IRKSYGNKLnkqeVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEkqlaefRKQHLG 96
Cdd:cd03300 6 VSKFYGGFV----ALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDGKDITNLPP------HKRPVN 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 97 FIFQDYNLLDTLTVKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPSIIFAD 176
Cdd:cd03300 76 TVFQNYALFPHLTVFENIAFGLRLKKLPKAEIKERVAEALDLVQLEGYANRKPSQLSGGQQQRVAIARALVNEPKVLLLD 155
|
170 180 190
....*....|....*....|....*....|....*
8G4D_C 177 EPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHD 211
Cdd:cd03300 156 EPLGALDLKLRKDMQLELKRLQKELGITFVFVTHD 190
|
|
| ABC_Class3 |
cd03229 |
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ... |
12-228 |
4.82e-51 |
|
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213196 [Multi-domain] Cd Length: 178 Bit Score: 164.67 E-value: 4.82e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 12 LEANKIRKSYGNKLnkqeVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMkEKQLAEFR 91
Cdd:cd03229 1 LELKNVSKRYGQKT----VLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIDGEDLTDL-EDELPPLR 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 92 kQHLGFIFQDYNLLDTLTVKENILLPLsitklskkeanrkfeevakelgiyelrdkypneiSGGQKQRTSAGRAFIHDPS 171
Cdd:cd03229 76 -RRIGMVFQDFALFPHLTVLENIALGL----------------------------------SGGQQQRVALARALAMDPD 120
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
8G4D_C 172 IIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHDP-VAASYCGRVIFIKDGQ 228
Cdd:cd03229 121 VLLLDEPTSALDPITRREVRALLKSLQAQLGITVVLVTHDLdEAARLADRVVVLRDGK 178
|
|
| ABC_Iron-Siderophores_B12_Hemin |
cd03214 |
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ... |
13-232 |
1.56e-50 |
|
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.
Pssm-ID: 213181 [Multi-domain] Cd Length: 180 Bit Score: 163.38 E-value: 1.56e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 13 EANKIRKSYGNKlnkqEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLAefrk 92
Cdd:cd03214 1 EVENLSVGYGGR----TVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLDGKDLASLSPKELA---- 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 93 QHLGFIFQdynlldtltvkenillplsitklskkeanrkfeeVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPSI 172
Cdd:cd03214 73 RKIAYVPQ----------------------------------ALELLGLAHLADRPFNELSGGERQRVLLARALAQEPPI 118
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
8G4D_C 173 IFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHDP-VAASYCGRVIFIKDGQMYTQ 232
Cdd:cd03214 119 LLLDEPTSHLDIAHQIELLELLRRLARERGKTVVMVLHDLnLAARYADRVILLKDGRIVAQ 179
|
|
| DppD |
COG0444 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
11-222 |
2.00e-49 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440213 [Multi-domain] Cd Length: 320 Bit Score: 165.23 E-value: 2.00e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 11 ILEANKIRKSYGNKLNKQEVLKGIDIHIEKGEFVSIMGASGSGKTTL----LNVLSSIDQVShGTIHINGNDMTAMKEKQ 86
Cdd:COG0444 1 LLEVRNLKVYFPTRRGVVKAVDGVSFDVRRGETLGLVGESGSGKSTLaraiLGLLPPPGITS-GEILFDGEDLLKLSEKE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 87 LAEFRKQHLGFIFQD-YNLLD-TLTVKENILLPLSI-TKLSKKEANRKFEEVAKELGI---YELRDKYPNEISGGQKQRT 160
Cdd:COG0444 80 LRKIRGREIQMIFQDpMTSLNpVMTVGDQIAEPLRIhGGLSKAEARERAIELLERVGLpdpERRLDRYPHELSGGMRQRV 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
8G4D_C 161 SAGRAFIHDPSIIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHD-PVAASYCGRVI 222
Cdd:COG0444 160 MIARALALEPKLLIADEPTTALDVTIQAQILNLLKDLQRELGLAILFITHDlGVVAEIADRVA 222
|
|
| ABC_phnC |
TIGR02315 |
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of ... |
11-228 |
2.17e-49 |
|
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of phosphorus-containing organic compound with a stable direct C-P bond rather than a C-O-P linkage. A number of bacterial species have operons, typically about 14 genes in size, with genes for ATP-dependent transport of phosphonates, degradation, and regulation of the expression of the system. Members of this protein family are the ATP-binding cassette component of tripartite ABC transporters of phosphonates. [Transport and binding proteins, Anions]
Pssm-ID: 131368 [Multi-domain] Cd Length: 243 Bit Score: 162.85 E-value: 2.17e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 11 ILEANKIRKSYGNklNKQeVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLAEF 90
Cdd:TIGR02315 1 MLEVENLSKVYPN--GKQ-ALKNINLNINPGEFVAIIGPSGAGKSTLLRCINRLVEPSSGSILLEGTDITKLRGKKLRKL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 91 RkQHLGFIFQDYNLLDTLTVKENIL---------LPLSITKLSKKEANRKFEEVAKeLGIYELRDKYPNEISGGQKQRTS 161
Cdd:TIGR02315 78 R-RRIGMIFQHYNLIERLTVLENVLhgrlgykptWRSLLGRFSEEDKERALSALER-VGLADKAYQRADQLSGGQQQRVA 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
8G4D_C 162 AGRAFIHDPSIIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHD-PVAASYCGRVIFIKDGQ 228
Cdd:TIGR02315 156 IARALAQQPDLILADEPIASLDPKTSKQVMDYLKRINKEDGITVIINLHQvDLAKKYADRIVGLKAGE 223
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
11-229 |
3.99e-49 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 168.93 E-value: 3.99e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 11 ILEANKIRKSYGNklNKQEVLKGIDIHIEKGEFVSIMGASGSGKTTL---LNVLSSIDQVSHGTIHINGNDMTAMKEKQl 87
Cdd:COG1123 4 LLEVRDLSVRYPG--GDVPAVDGVSLTIAPGETVALVGESGSGKSTLalaLMGLLPHGGRISGEVLLDGRDLLELSEAL- 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 88 aefRKQHLGFIFQDY-NLLDTLTVKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAF 166
Cdd:COG1123 81 ---RGRRIGMVFQDPmTQLNPVTVGDQIAEALENLGLSRAEARARVLELLEAVGLERRLDRYPHQLSGGQRQRVAIAMAL 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
8G4D_C 167 IHDPSIIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHDP-VAASYCGRVIFIKDGQM 229
Cdd:COG1123 158 ALDPDLLIADEPTTALDVTTQAEILDLLRELQRERGTTVLLITHDLgVVAEIADRVVVMDDGRI 221
|
|
| lolD |
PRK11629 |
lipoprotein-releasing ABC transporter ATP-binding protein LolD; |
11-233 |
2.11e-48 |
|
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
Pssm-ID: 183244 [Multi-domain] Cd Length: 233 Bit Score: 159.98 E-value: 2.11e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 11 ILEANKIRKSYGNKLNKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLAEF 90
Cdd:PRK11629 5 LLQCDNLCKRYQEGSVQTDVLHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNGQPMSKLSSAAKAEL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 91 RKQHLGFIFQDYNLLDTLTVKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDP 170
Cdd:PRK11629 85 RNQKLGFIYQFHHLLPDFTALENVAMPLLIGKKKPAEINSRALEMLAAVGLEHRANHRPSELSGGERQRVAIARALVNNP 164
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
8G4D_C 171 SIIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHDPVAASYCGRVIFIKDGQMYTQL 233
Cdd:PRK11629 165 RLVLADEPTGNLDARNADSIFQLLGELNRLQGTAFLVVTHDLQLAKRMSRQLEMRDGRLTAEL 227
|
|
| PhnT2 |
TIGR03265 |
putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ... |
12-211 |
5.10e-48 |
|
putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ATP-binding protein is found in a number of genomes in operon-like contexts strongly suggesting a substrate specificity for 2-aminoethylphosphonate (2-AEP). The characterized PhnSTUV system is absent in the genomes in which this system is found. These genomes encode systems for the catabolism of 2-AEP, making the need for a 2-AEP-specific transporter likely. [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 274496 [Multi-domain] Cd Length: 353 Bit Score: 162.51 E-value: 5.10e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 12 LEANKIRKSYGNklnkQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKqlaefr 91
Cdd:TIGR03265 5 LSIDNIRKRFGA----FTALKDISLSVKKGEFVCLLGPSGCGKTTLLRIIAGLERQTAGTIYQGGRDITRLPPQ------ 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 92 KQHLGFIFQDYNLLDTLTVKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPS 171
Cdd:TIGR03265 75 KRDYGIVFQSYALFPNLTVADNIAYGLKNRGMGRAEVAERVAELLDLVGLPGSERKYPGQLSGGQQQRVALARALATSPG 154
|
170 180 190 200
....*....|....*....|....*....|....*....|
8G4D_C 172 IIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHD 211
Cdd:TIGR03265 155 LLLLDEPLSALDARVREHLRTEIRQLQRRLGVTTIMVTHD 194
|
|
| ThiQ |
COG3840 |
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism]; |
12-228 |
9.57e-48 |
|
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
Pssm-ID: 443051 [Multi-domain] Cd Length: 232 Bit Score: 157.99 E-value: 9.57e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 12 LEANKIRKSYGNKLnkqevlKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQlaefR 91
Cdd:COG3840 2 LRLDDLTYRYGDFP------LRFDLTIAAGERVAILGPSGAGKSTLLNLIAGFLPPDSGRILWNGQDLTALPPAE----R 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 92 KqhLGFIFQDYNLLDTLTVKENILLPLSIT-KLSKKEAnRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDP 170
Cdd:COG3840 72 P--VSMLFQENNLFPHLTVAQNIGLGLRPGlKLTAEQR-AQVEQALERVGLAGLLDRLPGQLSGGQRQRVALARCLVRKR 148
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
8G4D_C 171 SIIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHDPV-AASYCGRVIFIKDGQ 228
Cdd:COG3840 149 PILLLDEPFSALDPALRQEMLDLVDELCRERGLTVLMVTHDPEdAARIADRVLLVADGR 207
|
|
| 3a0106s01 |
TIGR00968 |
sulfate ABC transporter, ATP-binding protein; [Transport and binding proteins, Anions] |
12-211 |
1.08e-47 |
|
sulfate ABC transporter, ATP-binding protein; [Transport and binding proteins, Anions]
Pssm-ID: 130041 [Multi-domain] Cd Length: 237 Bit Score: 158.42 E-value: 1.08e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 12 LEANKIRKSYGNKlnkqEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKekqlaeFR 91
Cdd:TIGR00968 1 IEIANISKRFGSF----QALDDVNLEVPTGSLVALLGPSGSGKSTLLRIIAGLEQPDSGRIRLNGQDATRVH------AR 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 92 KQHLGFIFQDYNLLDTLTVKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPS 171
Cdd:TIGR00968 71 DRKIGFVFQHYALFKHLTVRDNIAFGLEIRKHPKAKIKARVEELLELVQLEGLGDRYPNQLSGGQRQRVALARALAVEPQ 150
|
170 180 190 200
....*....|....*....|....*....|....*....|
8G4D_C 172 IIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHD 211
Cdd:TIGR00968 151 VLLLDEPFGALDAKVRKELRSWLRKLHDEVHVTTVFVTHD 190
|
|
| ABC_DR_subfamily_A |
cd03230 |
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ... |
12-229 |
4.41e-47 |
|
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213197 [Multi-domain] Cd Length: 173 Bit Score: 154.48 E-value: 4.41e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 12 LEANKIRKSYGNKlnkqEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQlaefr 91
Cdd:cd03230 1 IEVRNLSKRYGKK----TALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKVLGKDIKKEPEEV----- 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 92 KQHLGFIFQDYNLLDTLTVKENILLplsitklskkeanrkfeevakelgiyelrdkypneiSGGQKQRTSAGRAFIHDPS 171
Cdd:cd03230 72 KRRIGYLPEEPSLYENLTVRENLKL------------------------------------SGGMKQRLALAQALLHDPE 115
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
8G4D_C 172 IIFADEPTGALDSKSASDLLNKLSQLNqKRNATIIMVTHD-PVAASYCGRVIFIKDGQM 229
Cdd:cd03230 116 LLILDEPTSGLDPESRREFWELLRELK-KEGKTILLSSHIlEEAERLCDRVAILNNGRI 173
|
|
| CysA |
COG1118 |
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ... |
12-228 |
1.18e-46 |
|
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440735 [Multi-domain] Cd Length: 348 Bit Score: 158.77 E-value: 1.18e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 12 LEANKIRKSYGNKlnkqEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAmkekQLAEfR 91
Cdd:COG1118 3 IEVRNISKRFGSF----TLLDDVSLEIASGELVALLGPSGSGKTTLLRIIAGLETPDSGRIVLNGRDLFT----NLPP-R 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 92 KQHLGFIFQDYNLLDTLTVKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPS 171
Cdd:COG1118 74 ERRVGFVFQHYALFPHMTVAENIAFGLRVRPPSKAEIRARVEELLELVQLEGLADRYPSQLSGGQRQRVALARALAVEPE 153
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
8G4D_C 172 IIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHDPV-AASYCGRVIFIKDGQ 228
Cdd:COG1118 154 VLLLDEPFGALDAKVRKELRRWLRRLHDELGGTTVFVTHDQEeALELADRVVVMNQGR 211
|
|
| NatA |
COG4555 |
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ... |
12-229 |
1.27e-46 |
|
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];
Pssm-ID: 443618 [Multi-domain] Cd Length: 243 Bit Score: 155.79 E-value: 1.27e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 12 LEANKIRKSYGNKlnkqEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDmtamKEKQLAEFR 91
Cdd:COG4555 2 IEVENLSKKYGKV----PALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILIDGED----VRKEPREAR 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 92 KQhLGFIFQDYNLLDTLTVKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPS 171
Cdd:COG4555 74 RQ-IGVLPDERGLYDRLTVRENIRYFAELYGLFDEELKKRIEELIELLGLEEFLDRRVGELSTGMKKKVALARALVHDPK 152
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
8G4D_C 172 IIFADEPTGALDSKSASDLLNKLSQLNqKRNATIIMVTHDP-VAASYCGRVIFIKDGQM 229
Cdd:COG4555 153 VLLLDEPTNGLDVMARRLLREILRALK-KEGKTVLFSSHIMqEVEALCDRVVILHKGKV 210
|
|
| ABC_subfamily_A |
cd03263 |
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ... |
12-230 |
2.72e-46 |
|
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.
Pssm-ID: 213230 [Multi-domain] Cd Length: 220 Bit Score: 154.20 E-value: 2.72e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 12 LEANKIRKSYGNKLNKqeVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQlaefr 91
Cdd:cd03263 1 LQIRNLTKTYKKGTKP--AVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYINGYSIRTDRKAA----- 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 92 KQHLGFIFQDYNLLDTLTVKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPS 171
Cdd:cd03263 74 RQSLGYCPQFDALFDELTVREHLRFYARLKGLPKSEIKEEVELLLRVLGLTDKANKRARTLSGGMKRKLSLAIALIGGPS 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 172 IIFADEPTGALDSKSASDLLNKLSQLnqKRNATIIMVTHDP-VAASYCGRVIFIKDGQMY 230
Cdd:cd03263 154 VLLLDEPTSGLDPASRRAIWDLILEV--RKGRSIILTTHSMdEAEALCDRIAIMSDGKLR 211
|
|
| ABC_Pro_Gly_Betaine |
cd03294 |
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ... |
23-228 |
5.37e-45 |
|
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213261 [Multi-domain] Cd Length: 269 Bit Score: 152.41 E-value: 5.37e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 23 NKLNKQEVLKG---------IDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLAEFRKQ 93
Cdd:cd03294 23 KGKSKEEILKKtgqtvgvndVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIEPTSGKVLIDGQDIAAMSRKELRELRRK 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 94 HLGFIFQDYNLLDTLTVKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPSII 173
Cdd:cd03294 103 KISMVFQSFALLPHRTVLENVAFGLEVQGVPRAEREERAAEALELVGLEGWEHKYPDELSGGMQQRVGLARALAVDPDIL 182
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
8G4D_C 174 FADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHDPVAASYCG-RVIFIKDGQ 228
Cdd:cd03294 183 LMDEAFSALDPLIRREMQDELLRLQAELQKTIVFITHDLDEALRLGdRIAIMKDGR 238
|
|
| FetA |
COG4619 |
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism]; |
12-229 |
7.38e-45 |
|
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443661 [Multi-domain] Cd Length: 209 Bit Score: 149.97 E-value: 7.38e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 12 LEANKIRKSYGNKlnkqEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKekqLAEFR 91
Cdd:COG4619 1 LELEGLSFRVGGK----PILSPVSLTLEAGECVAITGPSGSGKSTLLRALADLDPPTSGEIYLDGKPLSAMP---PPEWR 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 92 KQhLGFIFQDYNLLDTlTVKENILLPLSITKLSKKEAnrKFEEVAKELGI-YELRDKYPNEISGGQKQRTSAGRAFIHDP 170
Cdd:COG4619 74 RQ-VAYVPQEPALWGG-TVRDNLPFPFQLRERKFDRE--RALELLERLGLpPDILDKPVERLSGGERQRLALIRALLLQP 149
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 171 SIIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHDP-VAASYCGRVIFIKDGQM 229
Cdd:COG4619 150 DVLLLDEPTSALDPENTRRVEELLREYLAEEGRAVLWVSHDPeQIERVADRVLTLEAGRL 209
|
|
| ABCC_MRP_Like |
cd03228 |
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ... |
12-228 |
1.36e-44 |
|
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213195 [Multi-domain] Cd Length: 171 Bit Score: 147.91 E-value: 1.36e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 12 LEANKIRKSYGNKlnKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDmtaMKEKQLAEFR 91
Cdd:cd03228 1 IEFKNVSFSYPGR--PKPVLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILIDGVD---LRDLDLESLR 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 92 KqHLGFIFQDYNLLDTlTVKENILlplsitklskkeanrkfeevakelgiyelrdkypneiSGGQKQRTSAGRAFIHDPS 171
Cdd:cd03228 76 K-NIAYVPQDPFLFSG-TIRENIL-------------------------------------SGGQRQRIAIARALLRDPP 116
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
8G4D_C 172 IIFADEPTGALDSKSASDLLNKLSQLNQKRnaTIIMVTHDPVAASYCGRVIFIKDGQ 228
Cdd:cd03228 117 ILILDEATSALDPETEALILEALRALAKGK--TVIVIAHRLSTIRDADRIIVLDDGR 171
|
|
| HisP |
COG4598 |
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism]; |
12-228 |
1.58e-44 |
|
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443652 [Multi-domain] Cd Length: 259 Bit Score: 150.72 E-value: 1.58e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 12 LEANKIRKSYGNklnkQEVLKGIDIHIEKGEFVSIMGASGSGKTTLL---NVLSSIDQvshGTIHING----------ND 78
Cdd:COG4598 9 LEVRDLHKSFGD----LEVLKGVSLTARKGDVISIIGSSGSGKSTFLrciNLLETPDS---GEIRVGGeeirlkpdrdGE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 79 MTAMKEKQLAEFRKQhLGFIFQDYNLLDTLTVKENILL-PLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQK 157
Cdd:COG4598 82 LVPADRRQLQRIRTR-LGMVFQSFNLWSHMTVLENVIEaPVHVLGRPKAEAIERAEALLAKVGLADKRDAYPAHLSGGQQ 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
8G4D_C 158 QRTSAGRAFIHDPSIIFADEPTGALDSKSASDLLNKLSQLNQK-RnaTIIMVTHD-PVAASYCGRVIFIKDGQ 228
Cdd:COG4598 161 QRAAIARALAMEPEVMLFDEPTSALDPELVGEVLKVMRDLAEEgR--TMLVVTHEmGFARDVSSHVVFLHQGR 231
|
|
| ABC_ModC_like |
cd03299 |
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ... |
12-230 |
3.16e-44 |
|
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213266 [Multi-domain] Cd Length: 235 Bit Score: 149.41 E-value: 3.16e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 12 LEANKIRKSYGNKlnkqeVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKqlaefr 91
Cdd:cd03299 1 LKVENLSKDWKEF-----KLKNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKILLNGKDITNLPPE------ 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 92 KQHLGFIFQDYNLLDTLTVKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPS 171
Cdd:cd03299 70 KRDISYVPQNYALFPHMTVYKNIAYGLKKRKVDKKEIERKVLEIAEMLGIDHLLNRKPETLSGGEQQRVAIARALVVNPK 149
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 172 IIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHDPV-AASYCGRVIFIKDGQMY 230
Cdd:cd03299 150 ILLLDEPFSALDVRTKEKLREELKKIRKEFGVTVLHVTHDFEeAWALADKVAIMLNGKLI 209
|
|
| PRK11264 |
PRK11264 |
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional |
24-232 |
4.38e-44 |
|
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
Pssm-ID: 183063 [Multi-domain] Cd Length: 250 Bit Score: 149.52 E-value: 4.38e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 24 KLNKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTI-----HINGNDMTAMKEKQLAEFRkQHLGFI 98
Cdd:PRK11264 12 KFHGQTVLHGIDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGTIrvgdiTIDTARSLSQQKGLIRQLR-QHVGFV 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 99 FQDYNLLDTLTVKENILL-PLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPSIIFADE 177
Cdd:PRK11264 91 FQNFNLFPHRTVLENIIEgPVIVKGEPKEEATARARELLAKVGLAGKETSYPRRLSGGQQQRVAIARALAMRPEVILFDE 170
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
8G4D_C 178 PTGALDSKSASDLLNKLSQLNQKRNaTIIMVTHD-PVAASYCGRVIFIKDGQMYTQ 232
Cdd:PRK11264 171 PTSALDPELVGEVLNTIRQLAQEKR-TMVIVTHEmSFARDVADRAIFMDQGRIVEQ 225
|
|
| tungstate_WtpC |
NF040840 |
tungstate ABC transporter ATP-binding protein WtpC; |
11-229 |
2.40e-42 |
|
tungstate ABC transporter ATP-binding protein WtpC;
Pssm-ID: 468779 [Multi-domain] Cd Length: 347 Bit Score: 147.53 E-value: 2.40e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 11 ILEANKIRKSYgnklnKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKqlaef 90
Cdd:NF040840 1 MIRIENLSKDW-----KEFKLRDISLEVKEGEYFIILGPSGAGKTVLLELIAGIWPPDSGKIYLDGKDITNLPPE----- 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 91 rKQHLGFIFQDYNLLDTLTVKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDP 170
Cdd:NF040840 71 -KRGIAYVYQNYMLFPHKTVFENIAFGLKLRKVPKEEIERKVKEIMELLGISHLLHRKPRTLSGGEQQRVALARALIIEP 149
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 171 SIIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHD-PVAASYCGRVIFIKDGQM 229
Cdd:NF040840 150 KLLLLDEPLSALDVQTRDELIREMKRWHREFGFTAIHVTHNfEEALSLADRVGIMLNGRL 209
|
|
| ABC_tran |
pfam00005 |
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ... |
31-179 |
2.58e-42 |
|
ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.
Pssm-ID: 394964 [Multi-domain] Cd Length: 150 Bit Score: 141.63 E-value: 2.58e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 31 LKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLaefrKQHLGFIFQDYNLLDTLTV 110
Cdd:pfam00005 1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDDERKSL----RKEIGYVFQDPQLFPRLTV 76
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
8G4D_C 111 KENILLPLSITKLSKKEANRKFEEVAKELGIYELRD----KYPNEISGGQKQRTSAGRAFIHDPSIIFADEPT 179
Cdd:pfam00005 77 RENLRLGLLLKGLSKREKDARAEEALEKLGLGDLADrpvgERPGTLSGGQRQRVAIARALLTKPKLLLLDEPT 149
|
|
| CydD |
COG4988 |
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ... |
28-228 |
1.00e-41 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444012 [Multi-domain] Cd Length: 563 Bit Score: 149.91 E-value: 1.00e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 28 QEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLAefrkQHLGFIFQDYNLLDT 107
Cdd:COG4988 350 RPALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPYSGSILINGVDLSDLDPASWR----RQIAWVPQNPYLFAG 425
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 108 lTVKENILLplsitklSKKEANRK-FEEVAKELGIYELRDKYPN-------E----ISGGQKQRTSAGRAFIHDPSIIFA 175
Cdd:COG4988 426 -TIRENLRL-------GRPDASDEeLEAALEAAGLDEFVAALPDgldtplgEggrgLSGGQAQRLALARALLRDAPLLLL 497
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
8G4D_C 176 DEPTGALDSKSASDLLNKLSQLnqKRNATIIMVTHDPVAASYCGRVIFIKDGQ 228
Cdd:COG4988 498 DEPTAHLDAETEAEILQALRRL--AKGRTVILITHRLALLAQADRILVLDDGR 548
|
|
| ABC_CysA_sulfate_importer |
cd03296 |
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ... |
17-211 |
2.83e-41 |
|
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213263 [Multi-domain] Cd Length: 239 Bit Score: 141.71 E-value: 2.83e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 17 IRKSYGNKlnkqEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKekqlaeFRKQHLG 96
Cdd:cd03296 8 VSKRFGDF----VALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFGGEDATDVP------VQERNVG 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 97 FIFQDYNLLDTLTVKENILLPLSITK----LSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPSI 172
Cdd:cd03296 78 FVFQHYALFRHMTVFDNVAFGLRVKPrserPPEAEIRAKVHELLKLVQLDWLADRYPAQLSGGQRQRVALARALAVEPKV 157
|
170 180 190
....*....|....*....|....*....|....*....
8G4D_C 173 IFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHD 211
Cdd:cd03296 158 LLLDEPFGALDAKVRKELRRWLRRLHDELHVTTVFVTHD 196
|
|
| SunT |
COG2274 |
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ... |
26-229 |
8.50e-41 |
|
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];
Pssm-ID: 441875 [Multi-domain] Cd Length: 711 Bit Score: 148.83 E-value: 8.50e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 26 NKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKekqLAEFRKQhLGFIFQDYNLL 105
Cdd:COG2274 486 DSPPVLDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEPTSGRILIDGIDLRQID---PASLRRQ-IGVVLQDVFLF 561
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 106 DTlTVKENILlplsitkLSKKEANR-KFEEVAKELGIYELRDKYPN-----------EISGGQKQRTSAGRAFIHDPSII 173
Cdd:COG2274 562 SG-TIRENIT-------LGDPDATDeEIIEAARLAGLHDFIEALPMgydtvvgeggsNLSGGQRQRLAIARALLRNPRIL 633
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
8G4D_C 174 FADEPTGALDSKSASDLLNKLSQLNQKRnaTIIMVTHDPVAASYCGRVIFIKDGQM 229
Cdd:COG2274 634 ILDEATSALDAETEAIILENLRRLLKGR--TVIIIAHRLSTIRLADRIIVLDKGRI 687
|
|
| ntrCD |
TIGR01184 |
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ... |
31-211 |
1.02e-40 |
|
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]
Pssm-ID: 130252 [Multi-domain] Cd Length: 230 Bit Score: 139.91 E-value: 1.02e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 31 LKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLAefrkqhlgfIFQDYNLLDTLTV 110
Cdd:TIGR01184 1 LKGVNLTIQQGEFISLIGHSGCGKSTLLNLISGLAQPTSGGVILEGKQITEPGPDRMV---------VFQNYSLLPWLTV 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 111 KENILLPLS--ITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPSIIFADEPTGALDSKSAS 188
Cdd:TIGR01184 72 RENIALAVDrvLPDLSKSERRAIVEEHIALVGLTEAADKRPGQLSGGMKQRVAIARALSIRPKVLLLDEPFGALDALTRG 151
|
170 180
....*....|....*....|...
8G4D_C 189 DLLNKLSQLNQKRNATIIMVTHD 211
Cdd:TIGR01184 152 NLQEELMQIWEEHRVTVLMVTHD 174
|
|
| ABC_OpuCA_Osmoprotection |
cd03295 |
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ... |
12-211 |
1.32e-40 |
|
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213262 [Multi-domain] Cd Length: 242 Bit Score: 140.13 E-value: 1.32e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 12 LEANKIRKSYGNKlnkQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLaefr 91
Cdd:cd03295 1 IEFENVTKRYGGG---KKAVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIFIDGEDIREQDPVEL---- 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 92 KQHLGFIFQDYNLLDTLTVKENILLPLSITKLSKKEANRKFEEVAK--ELGIYELRDKYPNEISGGQKQRTSAGRAFIHD 169
Cdd:cd03295 74 RRKIGYVIQQIGLFPHMTVEENIALVPKLLKWPKEKIRERADELLAlvGLDPAEFADRYPHELSGGQQQRVGVARALAAD 153
|
170 180 190 200
....*....|....*....|....*....|....*....|..
8G4D_C 170 PSIIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHD 211
Cdd:cd03295 154 PPLLLMDEPFGALDPITRDQLQEEFKRLQQELGKTIVFVTHD 195
|
|
| PRK10851 |
PRK10851 |
sulfate/thiosulfate ABC transporter ATP-binding protein CysA; |
12-211 |
2.29e-40 |
|
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
Pssm-ID: 182778 [Multi-domain] Cd Length: 353 Bit Score: 142.53 E-value: 2.29e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 12 LEANKIRKSYGNKlnkqEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEkqlaefR 91
Cdd:PRK10851 3 IEIANIKKSFGRT----QVLNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIRFHGTDVSRLHA------R 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 92 KQHLGFIFQDYNLLDTLTVKENILLPLSI----TKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFI 167
Cdd:PRK10851 73 DRKVGFVFQHYALFRHMTVFDNIAFGLTVlprrERPNAAAIKAKVTQLLEMVQLAHLADRYPAQLSGGQKQRVALARALA 152
|
170 180 190 200
....*....|....*....|....*....|....*....|....
8G4D_C 168 HDPSIIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHD 211
Cdd:PRK10851 153 VEPQILLLDEPFGALDAQVRKELRRWLRQLHEELKFTSVFVTHD 196
|
|
| ABC_ThiQ_thiamine_transporter |
cd03298 |
ATP-binding cassette domain of the thiamine transport system; Part of the ... |
12-232 |
4.43e-40 |
|
ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213265 [Multi-domain] Cd Length: 211 Bit Score: 137.62 E-value: 4.43e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 12 LEANKIRKSYGnklnkqEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMkekqlaEFR 91
Cdd:cd03298 1 VRLDKIRFSYG------EQPMHFDLTFAQGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLINGVDVTAA------PPA 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 92 KQHLGFIFQDYNLLDTLTVKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPS 171
Cdd:cd03298 69 DRPVSMLFQENNLFAHLTVEQNVGLGLSPGLKLTAEDRQAIEVALARVGLAGLEKRLPGELSGGERQRVALARVLVRDKP 148
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
8G4D_C 172 IIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHDPVAASYCG-RVIFIKDGQMYTQ 232
Cdd:cd03298 149 VLLLDEPFAALDPALRAEMLDLVLDLHAETKMTVLMVTHQPEDAKRLAqRVVFLDNGRIAAQ 210
|
|
| ABC_ModC_molybdenum_transporter |
cd03297 |
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ... |
40-228 |
6.15e-40 |
|
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213264 [Multi-domain] Cd Length: 214 Bit Score: 137.43 E-value: 6.15e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 40 KGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLAEFRKQHLGFIFQDYNLLDTLTVKENILLPLS 119
Cdd:cd03297 22 NEEVTGIFGASGAGKSTLLRCIAGLEKPDGGTIVLNGTVLFDSRKKINLPPQQRKIGLVFQQYALFPHLNVRENLAFGLK 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 120 itKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPSIIFADEPTGALDSKSASDLLNKLSQLNQ 199
Cdd:cd03297 102 --RKRNREDRISVDELLDLLGLDHLLNRYPAQLSGGEKQRVALARALAAQPELLLLDEPFSALDRALRLQLLPELKQIKK 179
|
170 180 190
....*....|....*....|....*....|
8G4D_C 200 KRNATIIMVTHDPVAASY-CGRVIFIKDGQ 228
Cdd:cd03297 180 NLNIPVIFVTHDLSEAEYlADRIVVMEDGR 209
|
|
| ArtP |
COG4161 |
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism]; |
12-227 |
6.30e-40 |
|
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443326 [Multi-domain] Cd Length: 242 Bit Score: 138.22 E-value: 6.30e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 12 LEANKIRKSYGNklnkQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDM---TAMKEKQLA 88
Cdd:COG4161 3 IQLKNINCFYGS----HQALFDINLECPSGETLVLLGPSGAGKSSLLRVLNLLETPDSGQLNIAGHQFdfsQKPSEKAIR 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 89 EFRkQHLGFIFQDYNLLDTLTVKENIL-LPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFI 167
Cdd:COG4161 79 LLR-QKVGMVFQQYNLWPHLTVMENLIeAPCKVLGLSKEQAREKAMKLLARLRLTDKADRFPLHLSGGQQQRVAIARALM 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
8G4D_C 168 HDPSIIFADEPTGALDSKSASDLLNKLSQLNQKrNATIIMVTHD-PVAASYCGRVIFIKDG 227
Cdd:COG4161 158 MEPQVLLFDEPTAALDPEITAQVVEIIRELSQT-GITQVIVTHEvEFARKVASQVVYMEKG 217
|
|
| ECF_ATPase_2 |
TIGR04521 |
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ... |
31-228 |
6.75e-40 |
|
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the downstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 275314 [Multi-domain] Cd Length: 277 Bit Score: 139.12 E-value: 6.75e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 31 LKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLAEFRKQhLGFIFQ--DYNLLDTl 108
Cdd:TIGR04521 21 LDDVSLTIEDGEFVAIIGHTGSGKSTLIQHLNGLLKPTSGTVTIDGRDITAKKKKKLKDLRKK-VGLVFQfpEHQLFEE- 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 109 TVKENILLPLSITKLSKKEANRKFEEVAKELGI-YELRDKYPNEISGGQKQRTS-AGrAFIHDPSIIFADEPTGALDSKS 186
Cdd:TIGR04521 99 TVYKDIAFGPKNLGLSEEEAEERVKEALELVGLdEEYLERSPFELSGGQMRRVAiAG-VLAMEPEVLILDEPTAGLDPKG 177
|
170 180 190 200
....*....|....*....|....*....|....*....|...
8G4D_C 187 ASDLLNKLSQLNQKRNATIIMVTHD-PVAASYCGRVIFIKDGQ 228
Cdd:TIGR04521 178 RKEILDLFKRLHKEKGLTVILVTHSmEDVAEYADRVIVMHKGK 220
|
|
| ABC_ATPase |
cd00267 |
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ... |
13-228 |
1.82e-39 |
|
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 134.29 E-value: 1.82e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 13 EANKIRKSYGNKlnkqEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLaefrK 92
Cdd:cd00267 1 EIENLSFRYGGR----TALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDGKDIAKLPLEEL----R 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 93 QHLGFIFQdynlldtltvkenillplsitklskkeanrkfeevakelgiyelrdkypneISGGQKQRTSAGRAFIHDPSI 172
Cdd:cd00267 73 RRIGYVPQ---------------------------------------------------LSGGQRQRVALARALLLNPDL 101
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
8G4D_C 173 IFADEPTGALDSKSASDLLNKLSQLNQKrNATIIMVTHDP-VAASYCGRVIFIKDGQ 228
Cdd:cd00267 102 LLLDEPTSGLDPASRERLLELLRELAEE-GRTVIIVTHDPeLAELAADRVIVLKDGK 157
|
|
| PRK10619 |
PRK10619 |
histidine ABC transporter ATP-binding protein HisP; |
12-229 |
2.38e-39 |
|
histidine ABC transporter ATP-binding protein HisP;
Pssm-ID: 182592 [Multi-domain] Cd Length: 257 Bit Score: 137.41 E-value: 2.38e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 12 LEANKIRKSYGnklnKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEK--QLAE 89
Cdd:PRK10619 6 LNVIDLHKRYG----EHEVLKGVSLQANAGDVISIIGSSGSGKSTFLRCINFLEKPSEGSIVVNGQTINLVRDKdgQLKV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 90 FRKQHL-------GFIFQDYNLLDTLTVKENIL-LPLSITKLSKKEANRKFEEVAKELGIYE-LRDKYPNEISGGQKQRT 160
Cdd:PRK10619 82 ADKNQLrllrtrlTMVFQHFNLWSHMTVLENVMeAPIQVLGLSKQEARERAVKYLAKVGIDErAQGKYPVHLSGGQQQRV 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 161 SAGRAFIHDPSIIFADEPTGALDSKSASDLLNKLSQLNQKrNATIIMVTHD-PVAASYCGRVIFIKDGQM 229
Cdd:PRK10619 162 SIARALAMEPEVLLFDEPTSALDPELVGEVLRIMQQLAEE-GKTMVVVTHEmGFARHVSSHVIFLHQGKI 230
|
|
| ZnuC |
COG1121 |
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
11-228 |
2.44e-39 |
|
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440738 [Multi-domain] Cd Length: 245 Bit Score: 136.76 E-value: 2.44e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 11 ILEANKIRKSYGNKLnkqeVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEK----- 85
Cdd:COG1121 6 AIELENLTVSYGGRP----VLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRLFGKPPRRARRRigyvp 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 86 QLAEFrkqhlgfifqDYNLldTLTVKENILL----PLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTS 161
Cdd:COG1121 82 QRAEV----------DWDF--PITVRDVVLMgrygRRGLFRRPSRADREAVDEALERVGLEDLADRPIGELSGGQQQRVL 149
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
8G4D_C 162 AGRAFIHDPSIIFADEPTGALDSKSASDLLNKLSQLNQkRNATIIMVTHDP-VAASYCGRVIFIKDGQ 228
Cdd:COG1121 150 LARALAQDPDLLLLDEPFAGVDAATEEALYELLRELRR-EGKTILVVTHDLgAVREYFDRVLLLNRGL 216
|
|
| glnQ |
PRK09493 |
glutamine ABC transporter ATP-binding protein GlnQ; |
11-227 |
2.64e-39 |
|
glutamine ABC transporter ATP-binding protein GlnQ;
Pssm-ID: 181906 [Multi-domain] Cd Length: 240 Bit Score: 136.76 E-value: 2.64e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 11 ILEANKIRKSYGnklnKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMT--AMKEKQLa 88
Cdd:PRK09493 1 MIEFKNVSKHFG----PTQVLHNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITSGDLIVDGLKVNdpKVDERLI- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 89 efrKQHLGFIFQDYNLLDTLTVKENILL-PLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFI 167
Cdd:PRK09493 76 ---RQEAGMVFQQFYLFPHLTALENVMFgPLRVRGASKEEAEKQARELLAKVGLAERAHHYPSELSGGQQQRVAIARALA 152
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
8G4D_C 168 HDPSIIFADEPTGALDSKSASDLLNKLSQLNQKrNATIIMVTHDPVAASYCG-RVIFIKDG 227
Cdd:PRK09493 153 VKPKLMLFDEPTSALDPELRHEVLKVMQDLAEE-GMTMVIVTHEIGFAEKVAsRLIFIDKG 212
|
|
| PRK10908 |
PRK10908 |
cell division ATP-binding protein FtsE; |
16-241 |
2.79e-39 |
|
cell division ATP-binding protein FtsE;
Pssm-ID: 182829 [Multi-domain] Cd Length: 222 Bit Score: 136.16 E-value: 2.79e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 16 KIRKSYgnkLNKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLAEFRKQhL 95
Cdd:PRK10908 6 HVSKAY---LGGRQALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKIWFSGHDITRLKNREVPFLRRQ-I 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 96 GFIFQDYNLLDTLTVKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPSIIFA 175
Cdd:PRK10908 82 GMIFQDHHLLMDRTVYDNVAIPLIIAGASGDDIRRRVSAALDKVGLLDKAKNFPIQLSGGEQQRVGIARAVVNKPAVLLA 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
8G4D_C 176 DEPTGALDSKSASDLLNKLSQLNqKRNATIIMVTHD-PVAASYCGRVIFIKDGQMYtqlnkGGQDRQ 241
Cdd:PRK10908 162 DEPTGNLDDALSEGILRLFEEFN-RVGVTVLMATHDiGLISRRSYRMLTLSDGHLH-----GGVGGE 222
|
|
| potA |
PRK09452 |
spermidine/putrescine ABC transporter ATP-binding protein PotA; |
11-228 |
3.70e-39 |
|
spermidine/putrescine ABC transporter ATP-binding protein PotA;
Pssm-ID: 236523 [Multi-domain] Cd Length: 375 Bit Score: 139.70 E-value: 3.70e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 11 ILEANKIRKSYGNKlnkqEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTamkeKQLAEf 90
Cdd:PRK09452 14 LVELRGISKSFDGK----EVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIMLDGQDIT----HVPAE- 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 91 rKQHLGFIFQDYNLLDTLTVKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDP 170
Cdd:PRK09452 85 -NRHVNTVFQSYALFPHMTVFENVAFGLRMQKTPAAEITPRVMEALRMVQLEEFAQRKPHQLSGGQQQRVAIARAVVNKP 163
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
8G4D_C 171 SIIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHDPVAA-SYCGRVIFIKDGQ 228
Cdd:PRK09452 164 KVLLLDESLSALDYKLRKQMQNELKALQRKLGITFVFVTHDQEEAlTMSDRIVVMRDGR 222
|
|
| TauB |
COG4525 |
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism]; |
12-211 |
9.12e-39 |
|
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443596 [Multi-domain] Cd Length: 262 Bit Score: 135.76 E-value: 9.12e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 12 LEANKIRKSYGNKLNKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKekqlAEfR 91
Cdd:COG4525 4 LTVRHVSVRYPGGGQPQPALQDVSLTIESGEFVVALGASGCGKTTLLNLIAGFLAPSSGEITLDGVPVTGPG----AD-R 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 92 kqhlGFIFQDYNLLDTLTVKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPS 171
Cdd:COG4525 79 ----GVVFQKDALLPWLNVLDNVAFGLRLRGVPKAERRARAEELLALVGLADFARRRIWQLSGGMRQRVGIARALAADPR 154
|
170 180 190 200
....*....|....*....|....*....|....*....|...
8G4D_C 172 IIFADEPTGALDS---KSASDLLNKLSQLNQKrnaTIIMVTHD 211
Cdd:COG4525 155 FLLMDEPFGALDAltrEQMQELLLDVWQRTGK---GVFLITHS 194
|
|
| ABC_PstB_phosphate_transporter |
cd03260 |
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ... |
12-229 |
1.99e-38 |
|
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).
Pssm-ID: 213227 [Multi-domain] Cd Length: 227 Bit Score: 133.85 E-value: 1.99e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 12 LEANKIRKSYGNKlnkqEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLS-SIDQVSH----GTIHINGNDMTAMKEKQ 86
Cdd:cd03260 1 IELRDLNVYYGDK----HALKDISLDIPKGEITALIGPSGCGKSTLLRLLNrLNDLIPGapdeGEVLLDGKDIYDLDVDV 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 87 LaEFRKQhLGFIFQDYNLLDtLTVKENILLPLSITKLSKKEANRkfEEVAKELGIYELRDK-----YPNEISGGQKQRTS 161
Cdd:cd03260 77 L-ELRRR-VGMVFQKPNPFP-GSIYDNVAYGLRLHGIKLKEELD--ERVEEALRKAALWDEvkdrlHALGLSGGQQQRLC 151
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
8G4D_C 162 AGRAFIHDPSIIFADEPTGALDSKSAS---DLLNKLsqlnqKRNATIIMVTHDPVAASYCG-RVIFIKDGQM 229
Cdd:cd03260 152 LARALANEPEVLLLDEPTSALDPISTAkieELIAEL-----KKEYTIVIVTHNMQQAARVAdRTAFLLNGRL 218
|
|
| thiQ |
TIGR01277 |
thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ... |
35-229 |
3.69e-38 |
|
thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ATPase subunit ThiQ of the ThiBPQ thiamine (and thiamine pyrophosphate) ABC transporter in several Proteobacteria. This protein is found so far only in Proteobacteria, and is found in complete genomes only if the ThiB and ThiP subunits are also found. [Transport and binding proteins, Other]
Pssm-ID: 130344 [Multi-domain] Cd Length: 213 Bit Score: 133.06 E-value: 3.69e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 35 DIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTamkekQLAEFRKQhLGFIFQDYNLLDTLTVKENI 114
Cdd:TIGR01277 18 DLNVADGEIVAIMGPSGAGKSTLLNLIAGFIEPASGSIKVNDQSHT-----GLAPYQRP-VSMLFQENNLFAHLTVRQNI 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 115 LLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPSIIFADEPTGALDSKSASDLLNKL 194
Cdd:TIGR01277 92 GLGLHPGLKLNAEQQEKVVDAAQQVGIADYLDRLPEQLSGGQRQRVALARCLVRPNPILLLDEPFSALDPLLREEMLALV 171
|
170 180 190
....*....|....*....|....*....|....*.
8G4D_C 195 SQLNQKRNATIIMVTHDPV-AASYCGRVIFIKDGQM 229
Cdd:TIGR01277 172 KQLCSERQRTLLMVTHHLSdARAIASQIAVVSQGKI 207
|
|
| ugpC |
PRK11650 |
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC; |
17-215 |
8.96e-38 |
|
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
Pssm-ID: 236947 [Multi-domain] Cd Length: 356 Bit Score: 135.74 E-value: 8.96e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 17 IRKSYGNKlnkQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAM--KEKQLAefrkqh 94
Cdd:PRK11650 9 VRKSYDGK---TQVIKGIDLDVADGEFIVLVGPSGCGKSTLLRMVAGLERITSGEIWIGGRVVNELepADRDIA------ 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 95 lgFIFQDYNLLDTLTVKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPSIIF 174
Cdd:PRK11650 80 --MVFQNYALYPHMSVRENMAYGLKIRGMPKAEIEERVAEAARILELEPLLDRKPRELSGGQRQRVAMGRAIVREPAVFL 157
|
170 180 190 200
....*....|....*....|....*....|....*....|.
8G4D_C 175 ADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHDPVAA 215
Cdd:PRK11650 158 FDEPLSNLDAKLRVQMRLEIQRLHRRLKTTSLYVTHDQVEA 198
|
|
| ssuB |
PRK11247 |
aliphatic sulfonates transport ATP-binding subunit; Provisional |
12-228 |
1.39e-37 |
|
aliphatic sulfonates transport ATP-binding subunit; Provisional
Pssm-ID: 183055 [Multi-domain] Cd Length: 257 Bit Score: 132.88 E-value: 1.39e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 12 LEANKIRKSYGNKlnkqEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIhINGNdmtamkeKQLAEFR 91
Cdd:PRK11247 13 LLLNAVSKRYGER----TVLNQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLETPSAGEL-LAGT-------APLAEAR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 92 KQhLGFIFQDYNLLDTLTVKENILLPLSITklSKKEANRKFEEVakelGIYELRDKYPNEISGGQKQRTSAGRAFIHDPS 171
Cdd:PRK11247 81 ED-TRLMFQDARLLPWKKVIDNVGLGLKGQ--WRDAALQALAAV----GLADRANEWPAALSGGQKQRVALARALIHRPG 153
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
8G4D_C 172 IIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHD-PVAASYCGRVIFIKDGQ 228
Cdd:PRK11247 154 LLLLDEPLGALDALTRIEMQDLIESLWQQHGFTVLLVTHDvSEAVAMADRVLLIEEGK 211
|
|
| OpuBA |
COG1125 |
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and ... |
17-211 |
2.12e-37 |
|
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440742 [Multi-domain] Cd Length: 306 Bit Score: 133.29 E-value: 2.12e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 17 IRKSYGNKlnkQEVLKGIDIHIEKGEFVSIMGASGSGKTTLL---NVLssIDQVShGTIHINGNDMTAMKEKQLaefrKQ 93
Cdd:COG1125 7 VTKRYPDG---TVAVDDLSLTIPAGEFTVLVGPSGCGKTTTLrmiNRL--IEPTS-GRILIDGEDIRDLDPVEL----RR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 94 HLGFIFQDYNLLDTLTVKENILLPLSITKLSKKEANRKFEEVAKELGIY--ELRDKYPNEISGGQKQRTSAGRAFIHDPS 171
Cdd:COG1125 77 RIGYVIQQIGLFPHMTVAENIATVPRLLGWDKERIRARVDELLELVGLDpeEYRDRYPHELSGGQQQRVGVARALAADPP 156
|
170 180 190 200
....*....|....*....|....*....|....*....|
8G4D_C 172 IIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHD 211
Cdd:COG1125 157 ILLMDEPFGALDPITREQLQDELLRLQRELGKTIVFVTHD 196
|
|
| ABCC_Protease_Secretion |
cd03246 |
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ... |
12-229 |
2.13e-37 |
|
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.
Pssm-ID: 213213 [Multi-domain] Cd Length: 173 Bit Score: 129.64 E-value: 2.13e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 12 LEANKIRKSYGNklNKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLaefr 91
Cdd:cd03246 1 LEVENVSFRYPG--AEPPVLRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRLDGADISQWDPNEL---- 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 92 KQHLGFIFQDYNLLDTlTVKENILlplsitklskkeanrkfeevakelgiyelrdkypneiSGGQKQRTSAGRAFIHDPS 171
Cdd:cd03246 75 GDHVGYLPQDDELFSG-SIAENIL-------------------------------------SGGQRQRLGLARALYGNPR 116
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
8G4D_C 172 IIFADEPTGALDSKSASDLLNKLSQLnQKRNATIIMVTHDPVAASYCGRVIFIKDGQM 229
Cdd:cd03246 117 ILVLDEPNSHLDVEGERALNQAIAAL-KAAGATRIVIAHRPETLASADRILVLEDGRV 173
|
|
| MdlB |
COG1132 |
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms]; |
20-228 |
3.06e-37 |
|
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
Pssm-ID: 440747 [Multi-domain] Cd Length: 579 Bit Score: 137.99 E-value: 3.06e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 20 SYGNKlnkQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKekqLAEFRKqHLGFIF 99
Cdd:COG1132 348 SYPGD---RPVLKDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDPTSGRILIDGVDIRDLT---LESLRR-QIGVVP 420
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 100 QDYNLLDTlTVKENILlplsitkLSKKEANR-KFEEVAKELGIYELRDKYPN-----------EISGGQKQRTSAGRAFI 167
Cdd:COG1132 421 QDTFLFSG-TIRENIR-------YGRPDATDeEVEEAAKAAQAHEFIEALPDgydtvvgergvNLSGGQRQRIAIARALL 492
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
8G4D_C 168 HDPSIIFADEPTGALDSKSASDLLNKLSQLNQKRnaTIIMVTHDPVAASYCGRVIFIKDGQ 228
Cdd:COG1132 493 KDPPILILDEATSALDTETEALIQEALERLMKGR--TTIVIAHRLSTIRNADRILVLDDGR 551
|
|
| ABC_Mj1267_LivG_branched |
cd03219 |
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ... |
12-222 |
1.04e-36 |
|
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).
Pssm-ID: 213186 [Multi-domain] Cd Length: 236 Bit Score: 129.86 E-value: 1.04e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 12 LEANKIRKSYGNKLnkqeVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLAefr 91
Cdd:cd03219 1 LEVRGLTKRFGGLV----ALDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSVLFDGEDITGLPPHEIA--- 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 92 kqHLGFI--FQDYNLLDTLTVKENILLP----------LSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQR 159
Cdd:cd03219 74 --RLGIGrtFQIPRLFPELTVLENVMVAaqartgsgllLARARREEREARERAEELLERVGLADLADRPAGELSYGQQRR 151
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
8G4D_C 160 TSAGRAFIHDPSIIFADEPTGALDSKSASDLLNKLSQLNQkRNATIIMVTHD-PVAASYCGRVI 222
Cdd:cd03219 152 LEIARALATDPKLLLLDEPAAGLNPEETEELAELIRELRE-RGITVLLVEHDmDVVMSLADRVT 214
|
|
| ECF_ATPase_1 |
TIGR04520 |
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ... |
12-232 |
1.39e-36 |
|
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 275313 [Multi-domain] Cd Length: 268 Bit Score: 130.24 E-value: 1.39e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 12 LEANKIRKSYGNklNKQEVLKGIDIHIEKGEFVSIMGASGSGKTTL---LNVLSSIDQvshGTIHINGndMTAMKEKQLA 88
Cdd:TIGR04520 1 IEVENVSFSYPE--SEKPALKNVSLSIEKGEFVAIIGHNGSGKSTLaklLNGLLLPTS---GKVTVDG--LDTLDEENLW 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 89 EFRkQHLGFIFQ--DyNLLDTLTVKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTS-AGrA 165
Cdd:TIGR04520 74 EIR-KKVGMVFQnpD-NQFVGATVEDDVAFGLENLGVPREEMRKRVDEALKLVGMEDFRDREPHLLSGGQKQRVAiAG-V 150
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
8G4D_C 166 FIHDPSIIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHDPVAASYCGRVIFIKDGQMYTQ 232
Cdd:TIGR04520 151 LAMRPDIIILDEATSMLDPKGRKEVLETIRKLNKEEGITVISITHDMEEAVLADRVIVMNKGKIVAE 217
|
|
| artP |
PRK11124 |
arginine transporter ATP-binding subunit; Provisional |
12-232 |
1.40e-36 |
|
arginine transporter ATP-binding subunit; Provisional
Pssm-ID: 182980 [Multi-domain] Cd Length: 242 Bit Score: 129.75 E-value: 1.40e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 12 LEANKIRKSYGNklnkQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDM---TAMKEKQLA 88
Cdd:PRK11124 3 IQLNGINCFYGA----HQALFDITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLNIAGNHFdfsKTPSDKAIR 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 89 EFRkQHLGFIFQDYNLLDTLTVKEN-ILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFI 167
Cdd:PRK11124 79 ELR-RNVGMVFQQYNLWPHLTVQQNlIEAPCRVLGLSKDQALARAEKLLERLRLKPYADRFPLHLSGGQQQRVAIARALM 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
8G4D_C 168 HDPSIIFADEPTGALDSKSASDLLNKLSQLNQKrNATIIMVTHD-PVAASYCGRVIFIKDGQMYTQ 232
Cdd:PRK11124 158 MEPQVLLFDEPTAALDPEITAQIVSIIRELAET-GITQVIVTHEvEVARKTASRVVYMENGHIVEQ 222
|
|
| CydC |
COG4987 |
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ... |
12-228 |
1.77e-36 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444011 [Multi-domain] Cd Length: 569 Bit Score: 135.66 E-value: 1.77e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 12 LEANKIRKSYGNklNKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLAefr 91
Cdd:COG4987 334 LELEDVSFRYPG--AGRPVLDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDPQSGSITLGGVDLRDLDEDDLR--- 408
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 92 kQHLGFIFQDYNLLDTlTVKENILLplsitklSKKEAN-RKFEEVAKELGIYELRDKYPN-------E----ISGGQKQR 159
Cdd:COG4987 409 -RRIAVVPQRPHLFDT-TLRENLRL-------ARPDATdEELWAALERVGLGDWLAALPDgldtwlgEggrrLSGGERRR 479
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
8G4D_C 160 TSAGRAFIHDPSIIFADEPTGALDSKSASDLLNKLsqLNQKRNATIIMVTHDPVAASYCGRVIFIKDGQ 228
Cdd:COG4987 480 LALARALLRDAPILLLDEPTEGLDAATEQALLADL--LEALAGRTVLLITHRLAGLERMDRILVLEDGR 546
|
|
| ABC_DrrA |
cd03265 |
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ... |
12-229 |
2.34e-36 |
|
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213232 [Multi-domain] Cd Length: 220 Bit Score: 128.26 E-value: 2.34e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 12 LEANKIRKSYGNklnkQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTamkeKQLAEFR 91
Cdd:cd03265 1 IEVENLVKKYGD----FEAVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRATVAGHDVV----REPREVR 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 92 KQhLGFIFQDYNLLDTLTVKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPS 171
Cdd:cd03265 73 RR-IGIVFQDLSVDDELTGWENLYIHARLYGVPGAERRERIDELLDFVGLLEAADRLVKTYSGGMRRRLEIARSLVHRPE 151
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
8G4D_C 172 IIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHD-PVAASYCGRVIFIKDGQM 229
Cdd:cd03265 152 VLFLDEPTIGLDPQTRAHVWEYIEKLKEEFGMTILLTTHYmEEAEQLCDRVAIIDHGRI 210
|
|
| ABC_cobalt_CbiO_domain2 |
cd03226 |
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ... |
13-228 |
2.43e-36 |
|
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213193 [Multi-domain] Cd Length: 205 Bit Score: 127.76 E-value: 2.43e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 13 EANKIRKSYGNKlnkQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMtamKEKQlaefRK 92
Cdd:cd03226 1 RIENISFSYKKG---TEILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSGSILLNGKPI---KAKE----RR 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 93 QHLGFIFQD--YNLLdTLTVKENILLPLSITKLSKKEAnrkfEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDP 170
Cdd:cd03226 71 KSIGYVMQDvdYQLF-TDSVREELLLGLKELDAGNEQA----ETVLKDLDLYALKERHPLSLSGGQKQRLAIAAALLSGK 145
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
8G4D_C 171 SIIFADEPTGALDS---KSASDLLNKLsqlnQKRNATIIMVTHDP-VAASYCGRVIFIKDGQ 228
Cdd:cd03226 146 DLLIFDEPTSGLDYknmERVGELIREL----AAQGKAVIVITHDYeFLAKVCDRVLLLANGA 203
|
|
| cbiO |
PRK13632 |
cobalt transporter ATP-binding subunit; Provisional |
10-232 |
1.71e-35 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237452 [Multi-domain] Cd Length: 271 Bit Score: 127.80 E-value: 1.71e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 10 VILEANKIRKSYGNklNKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAmkeKQLAE 89
Cdd:PRK13632 6 VMIKVENVSFSYPN--SENNALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIKIDGITISK---ENLKE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 90 FRKqHLGFIFQDY-NLLDTLTVKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIH 168
Cdd:PRK13632 81 IRK-KIGIIFQNPdNQFIGATVEDDIAFGLENKKVPPKKMKDIIDDLAKKVGMEDYLDKEPQNLSGGQKQRVAIASVLAL 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
8G4D_C 169 DPSIIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHDPVAASYCGRVIFIKDGQMYTQ 232
Cdd:PRK13632 160 NPEIIIFDESTSMLDPKGKREIKKIMVDLRKTRKKTLISITHDMDEAILADKVIVFSEGKLIAQ 223
|
|
| thiQ |
PRK10771 |
thiamine ABC transporter ATP-binding protein ThiQ; |
35-230 |
3.25e-35 |
|
thiamine ABC transporter ATP-binding protein ThiQ;
Pssm-ID: 182716 [Multi-domain] Cd Length: 232 Bit Score: 125.85 E-value: 3.25e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 35 DIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQlaefrkQHLGFIFQDYNLLDTLTVKENI 114
Cdd:PRK10771 19 DLTVERGERVAILGPSGAGKSTLLNLIAGFLTPASGSLTLNGQDHTTTPPSR------RPVSMLFQENNLFSHLTVAQNI 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 115 LLPLSIT-KLSKkEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPSIIFADEPTGALDSKSASDLLNK 193
Cdd:PRK10771 93 GLGLNPGlKLNA-AQREKLHAIARQMGIEDLLARLPGQLSGGQRQRVALARCLVREQPILLLDEPFSALDPALRQEMLTL 171
|
170 180 190 200
....*....|....*....|....*....|....*....|
8G4D_C 194 LSQLNQKRNATIIMVTH---DpvAASYCGRVIFIKDGQMY 230
Cdd:PRK10771 172 VSQVCQERQLTLLMVSHsleD--AARIAPRSLVVADGRIA 209
|
|
| ABC_NatA_sodium_exporter |
cd03266 |
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ... |
11-227 |
5.71e-35 |
|
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.
Pssm-ID: 213233 [Multi-domain] Cd Length: 218 Bit Score: 124.79 E-value: 5.71e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 11 ILEANKIRKSYGNKLNKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDmtAMKEKQLAef 90
Cdd:cd03266 1 MITADALTKRFRDVKKTVQAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATVDGFD--VVKEPAEA-- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 91 rKQHLGFIFQDYNLLDTLTVKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDP 170
Cdd:cd03266 77 -RRRLGFVSDSTGLYDRLTARENLEYFAGLYGLKGDELTARLEELADRLGMEELLDRRVGGFSTGMRQKVAIARALVHDP 155
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
8G4D_C 171 SIIFADEPTGALDSKSASDLLNKLSQLnQKRNATIIMVTHD-PVAASYCGRVIFIKDG 227
Cdd:cd03266 156 PVLLLDEPTTGLDVMATRALREFIRQL-RALGKCILFSTHImQEVERLCDRVVVLHRG 212
|
|
| ABCG_White |
cd03234 |
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ... |
23-212 |
5.94e-35 |
|
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.
Pssm-ID: 213201 [Multi-domain] Cd Length: 226 Bit Score: 125.08 E-value: 5.94e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 23 NKLNKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQ---VSHGTIHINGNDMTAmkekqlAEFRKqHLGFIF 99
Cdd:cd03234 15 NWNKYARILNDVSLHVESGQVMAILGSSGSGKTTLLDAISGRVEgggTTSGQILFNGQPRKP------DQFQK-CVAYVR 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 100 QDYNLLDTLTVKENIL--LPLSITKLSKKEANRKFEEVA--KELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPSIIFA 175
Cdd:cd03234 88 QDDILLPGLTVRETLTytAILRLPRKSSDAIRKKRVEDVllRDLALTRIGGNLVKGISGGERRRVSIAVQLLWDPKVLIL 167
|
170 180 190
....*....|....*....|....*....|....*..
8G4D_C 176 DEPTGALDSKSASDLLNKLSQLnQKRNATIIMVTHDP 212
Cdd:cd03234 168 DEPTSGLDSFTALNLVSTLSQL-ARRNRIVILTIHQP 203
|
|
| CcmA |
COG4133 |
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ... |
12-221 |
1.45e-34 |
|
ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443308 [Multi-domain] Cd Length: 206 Bit Score: 123.36 E-value: 1.45e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 12 LEANKIRKSYGNKLnkqeVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDmtamKEKQLAEFR 91
Cdd:COG4133 3 LEAENLSCRRGERL----LFSGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLWNGEP----IRDAREDYR 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 92 kQHLGFIFQDYNLLDTLTVKENILLplsITKLSKKEANR-KFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDP 170
Cdd:COG4133 75 -RRLAYLGHADGLKPELTVRENLRF---WAALYGLRADReAIDEALEAVGLAGLADLPVRQLSAGQKRRVALARLLLSPA 150
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
8G4D_C 171 SIIFADEPTGALDSKSASDLLNKLSQLNQKRnATIIMVTHDPVAASYCGRV 221
Cdd:COG4133 151 PLWLLDEPFTALDAAGVALLAELIAAHLARG-GAVLLTTHQPLELAAARVL 200
|
|
| PRK09984 |
PRK09984 |
phosphonate ABC transporter ATP-binding protein; |
11-230 |
1.59e-34 |
|
phosphonate ABC transporter ATP-binding protein;
Pssm-ID: 182182 [Multi-domain] Cd Length: 262 Bit Score: 124.74 E-value: 1.59e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 11 ILEANKIRKSYgnklNKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSI---DQVSHGTIHINGNdmTAMKEKQL 87
Cdd:PRK09984 4 IIRVEKLAKTF----NQHQALHAVDLNIHHGEMVALLGPSGSGKSTLLRHLSGLitgDKSAGSHIELLGR--TVQREGRL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 88 A-EFRKQ--HLGFIFQDYNLLDTLTVKENILL------PL------SITKLSKKEANRKFEEVakelGIYELRDKYPNEI 152
Cdd:PRK09984 78 ArDIRKSraNTGYIFQQFNLVNRLSVLENVLIgalgstPFwrtcfsWFTREQKQRALQALTRV----GMVHFAHQRVSTL 153
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
8G4D_C 153 SGGQKQRTSAGRAFIHDPSIIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHD-PVAASYCGRVIFIKDGQMY 230
Cdd:PRK09984 154 SGGQQQRVAIARALMQQAKVILADEPIASLDPESARIVMDTLRDINQNDGITVVVTLHQvDYALRYCERIVALRQGHVF 232
|
|
| ABC_YhbG |
cd03218 |
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ... |
12-200 |
3.87e-34 |
|
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.
Pssm-ID: 213185 [Multi-domain] Cd Length: 232 Bit Score: 123.04 E-value: 3.87e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 12 LEANKIRKSYGNKlnkqEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTamkekQLAEFR 91
Cdd:cd03218 1 LRAENLSKRYGKR----KVVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILLDGQDIT-----KLPMHK 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 92 KQHLGFIF--QDYNLLDTLTVKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHD 169
Cdd:cd03218 72 RARLGIGYlpQEASIFRKLTVEENILAVLEIRGLSKKEREEKLEELLEEFHITHLRKSKASSLSGGERRRVEIARALATN 151
|
170 180 190
....*....|....*....|....*....|.
8G4D_C 170 PSIIFADEPTGALDSKSASDLLNKLSQLNQK 200
Cdd:cd03218 152 PKFLLLDEPFAGVDPIAVQDIQKIIKILKDR 182
|
|
| ABC_Metallic_Cations |
cd03235 |
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ... |
20-225 |
9.34e-34 |
|
ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.
Pssm-ID: 213202 [Multi-domain] Cd Length: 213 Bit Score: 121.49 E-value: 9.34e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 20 SYGNKlnkqEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGndmtamkeKQLAEFRKQhLGFIF 99
Cdd:cd03235 8 SYGGH----PVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRVFG--------KPLEKERKR-IGYVP 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 100 QDYNLLDT--LTVKENILLPL-----SITKLSKKEAnRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPSI 172
Cdd:cd03235 75 QRRSIDRDfpISVRDVVLMGLyghkgLFRRLSKADK-AKVDEALERVGLSELADRQIGELSGGQQQRVLLARALVQDPDL 153
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
8G4D_C 173 IFADEPTGALDSKSASDLLNKLSQLNQKrNATIIMVTHDPVAAS-YCGRVIFIK 225
Cdd:cd03235 154 LLLDEPFAGVDPKTQEDIYELLRELRRE-GMTILVVTHDLGLVLeYFDRVLLLN 206
|
|
| PRK11000 |
PRK11000 |
maltose/maltodextrin ABC transporter ATP-binding protein MalK; |
19-235 |
9.67e-34 |
|
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
Pssm-ID: 182893 [Multi-domain] Cd Length: 369 Bit Score: 125.14 E-value: 9.67e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 19 KSYGNKLnkqeVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKqlaefrKQHLGFI 98
Cdd:PRK11000 11 KAYGDVV----ISKDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDITSGDLFIGEKRMNDVPPA------ERGVGMV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 99 FQDYNLLDTLTVKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPSIIFADEP 178
Cdd:PRK11000 81 FQSYALYPHLSVAENMSFGLKLAGAKKEEINQRVNQVAEVLQLAHLLDRKPKALSGGQRQRVAIGRTLVAEPSVFLLDEP 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
8G4D_C 179 TGALDSKSASDLLNKLSQLNQKRNATIIMVTHDPVAASYCGRVIFIKDGQMYTQLNK 235
Cdd:PRK11000 161 LSNLDAALRVQMRIEISRLHKRLGRTMIYVTHDQVEAMTLADKIVVLDAGRVAQVGK 217
|
|
| cbiO |
PRK13639 |
cobalt transporter ATP-binding subunit; Provisional |
11-243 |
1.36e-33 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184199 [Multi-domain] Cd Length: 275 Bit Score: 122.88 E-value: 1.36e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 11 ILEANKIRKSYGNKlnkQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKeKQLAEF 90
Cdd:PRK13639 1 ILETRDLKYSYPDG---TEALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEVLIKGEPIKYDK-KSLLEV 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 91 RKQhLGFIFQdyNLLDTL---TVKENILL-PLSItKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAF 166
Cdd:PRK13639 77 RKT-VGIVFQ--NPDDQLfapTVEEDVAFgPLNL-GLSKEEVEKRVKEALKAVGMEGFENKPPHHLSGGQKKRVAIAGIL 152
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
8G4D_C 167 IHDPSIIFADEPTGALDSKSASDLLNKLSQLNqKRNATIIMVTHD-PVAASYCGRVIFIKDGQMYtqlnKGGQDRQTF 243
Cdd:PRK13639 153 AMKPEIIVLDEPTSGLDPMGASQIMKLLYDLN-KEGITIIISTHDvDLVPVYADKVYVMSDGKII----KEGTPKEVF 225
|
|
| potA |
TIGR01187 |
spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine ... |
46-229 |
1.71e-33 |
|
spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine/putrescine ABC transporter, ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Polyamines like spermidine and putrescine play vital role in cell proliferation, differentiation, and ion homeostasis. The concentration of polyamines within the cell are regulated by biosynthesis, degradation and transport (uptake and efflux included). [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 162242 [Multi-domain] Cd Length: 325 Bit Score: 123.76 E-value: 1.71e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 46 IMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKekqlAEFRkqHLGFIFQDYNLLDTLTVKENILLPLSITKLSK 125
Cdd:TIGR01187 1 LLGPSGCGKTTLLRLLAGFEQPDSGSIMLDGEDVTNVP----PHLR--HINMVFQSYALFPHMTVEENVAFGLKMRKVPR 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 126 KEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPSIIFADEPTGALDSKSASDLLNKLSQLNQKRNATI 205
Cdd:TIGR01187 75 AEIKPRVLEALRLVQLEEFADRKPHQLSGGQQQRVALARALVFKPKILLLDEPLSALDKKLRDQMQLELKTIQEQLGITF 154
|
170 180
....*....|....*....|....*
8G4D_C 206 IMVTHDPVAA-SYCGRVIFIKDGQM 229
Cdd:TIGR01187 155 VFVTHDQEEAmTMSDRIAIMRKGKI 179
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
10-228 |
3.23e-33 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 126.34 E-value: 3.23e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 10 VILEANKIRKSYGNK---LNKQ----EVLKGIDIHIEKGEFVSIMGASGSGKTTL-LNVLSSIDqvSHGTIHINGNDMTA 81
Cdd:COG4172 274 PLLEARDLKVWFPIKrglFRRTvghvKAVDGVSLTLRRGETLGLVGESGSGKSTLgLALLRLIP--SEGEIRFDGQDLDG 351
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 82 MKEKQLAEFRKqHLGFIFQD-YNLLDT-LTVKENILLPLSI--TKLSKKEANRKFEEVAKELGI-YELRDKYPNEISGGQ 156
Cdd:COG4172 352 LSRRALRPLRR-RMQVVFQDpFGSLSPrMTVGQIIAEGLRVhgPGLSAAERRARVAEALEEVGLdPAARHRYPHEFSGGQ 430
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
8G4D_C 157 KQRTSAGRAFIHDPSIIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHD-PVAASYCGRVIFIKDGQ 228
Cdd:COG4172 431 RQRIAIARALILEPKLLVLDEPTSALDVSVQAQILDLLRDLQREHGLAYLFISHDlAVVRALAHRVMVMKDGK 503
|
|
| ABC_drug_resistance_like |
cd03264 |
ABC-type multidrug transport system, ATPase component; The biological function of this family ... |
12-228 |
3.86e-33 |
|
ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213231 [Multi-domain] Cd Length: 211 Bit Score: 119.61 E-value: 3.86e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 12 LEANKIRKSYGNKLnkqeVLKGIDIHIEKGEFVsIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKqlaeFR 91
Cdd:cd03264 1 LQLENLTKRYGKKR----ALDGVSLTLGPGMYG-LLGPNGAGKTTLMRILATLTPPSSGTIRIDGQDVLKQPQK----LR 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 92 kQHLGFIFQDYNLLDTLTVKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPS 171
Cdd:cd03264 72 -RRIGYLPQEFGVYPNFTVREFLDYIAWLKGIPSKEVKARVDEVLELVNLGDRAKKKIGSLSGGMRRRVGIAQALVGDPS 150
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
8G4D_C 172 IIFADEPTGALDSKSASDLLNKLSQLNQkrNATIIMVTH--DPVAASyCGRVIFIKDGQ 228
Cdd:cd03264 151 ILIVDEPTAGLDPEERIRFRNLLSELGE--DRIVILSTHivEDVESL-CNQVAVLNKGK 206
|
|
| hmuV |
PRK13548 |
hemin importer ATP-binding subunit; Provisional |
10-230 |
4.12e-33 |
|
hemin importer ATP-binding subunit; Provisional
Pssm-ID: 237422 [Multi-domain] Cd Length: 258 Bit Score: 121.03 E-value: 4.12e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 10 VILEANKIRKSYGNKlnkqEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLAE 89
Cdd:PRK13548 1 AMLEARNLSVRLGGR----TLLDDVSLTLRPGEVVAILGPNGAGKSTLLRALSGELSPDSGEVRLNGRPLADWSPAELAR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 90 FR---KQH--LGFIFqdynlldtlTVKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDK-YPnEISGGQKQRTSAG 163
Cdd:PRK13548 77 RRavlPQHssLSFPF---------TVEEVVAMGRAPHGLSRAEDDALVAAALAQVDLAHLAGRdYP-QLSGGEQQRVQLA 146
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
8G4D_C 164 RAFI------HDPSIIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHD-PVAASYCGRVIFIKDGQMY 230
Cdd:PRK13548 147 RVLAqlwepdGPPRWLLLDEPTSALDLAHQHHVLRLARQLAHERGLAVIVVLHDlNLAARYADRIVLLHQGRLV 220
|
|
| PhnK |
COG1101 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
11-228 |
4.30e-33 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 440718 [Multi-domain] Cd Length: 264 Bit Score: 120.96 E-value: 4.30e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 11 ILEANKIRKSYG-NKLNKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQlae 89
Cdd:COG1101 1 MLELKNLSKTFNpGTVNEKRALDGLNLTIEEGDFVTVIGSNGAGKSTLLNAIAGSLPPDSGSILIDGKDVTKLPEYK--- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 90 fRKQHLGFIFQDyNLLDT---LTVKENILL--------PLSITKLSKKEAnrKFEEVAKELGIyELRDKYPNEI---SGG 155
Cdd:COG1101 78 -RAKYIGRVFQD-PMMGTapsMTIEENLALayrrgkrrGLRRGLTKKRRE--LFRELLATLGL-GLENRLDTKVgllSGG 152
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
8G4D_C 156 QKQRTSAGRAFIHDPSIIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTH---DpvAASYCGRVIFIKDGQ 228
Cdd:COG1101 153 QRQALSLLMATLTKPKLLLLDEHTAALDPKTAALVLELTEKIVEENNLTTLMVTHnmeQ--ALDYGNRLIMMHEGR 226
|
|
| cbiO |
PRK13637 |
energy-coupling factor transporter ATPase; |
31-228 |
5.10e-33 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237455 [Multi-domain] Cd Length: 287 Bit Score: 121.69 E-value: 5.10e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 31 LKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKqLAEFRKQhLGFIFQ--DYNLLDTl 108
Cdd:PRK13637 23 LDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIIIDGVDITDKKVK-LSDIRKK-VGLVFQypEYQLFEE- 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 109 TVKENILLPLSITKLSKKEANRKFEEVAKELGI-YE-LRDKYPNEISGGQKQRTSAGRAFIHDPSIIFADEPTGALDSKS 186
Cdd:PRK13637 100 TIEKDIAFGPINLGLSEEEIENRVKRAMNIVGLdYEdYKDKSPFELSGGQKRRVAIAGVVAMEPKILILDEPTAGLDPKG 179
|
170 180 190 200
....*....|....*....|....*....|....*....|....
8G4D_C 187 ASDLLNKLSQLNQKRNATIIMVTH--DPVaASYCGRVIFIKDGQ 228
Cdd:PRK13637 180 RDEILNKIKELHKEYNMTIILVSHsmEDV-AKLADRIIVMNKGK 222
|
|
| potG |
PRK11607 |
putrescine ABC transporter ATP-binding subunit PotG; |
11-228 |
8.76e-33 |
|
putrescine ABC transporter ATP-binding subunit PotG;
Pssm-ID: 183226 [Multi-domain] Cd Length: 377 Bit Score: 123.02 E-value: 8.76e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 11 ILEANKIRKSYgnklNKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQlaef 90
Cdd:PRK11607 19 LLEIRNLTKSF----DGQHAVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIMLDGVDLSHVPPYQ---- 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 91 rkQHLGFIFQDYNLLDTLTVKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDP 170
Cdd:PRK11607 91 --RPINMMFQSYALFPHMTVEQNIAFGLKQDKLPKAEIASRVNEMLGLVHMQEFAKRKPHQLSGGQRQRVALARSLAKRP 168
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
8G4D_C 171 SIIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHD-PVAASYCGRVIFIKDGQ 228
Cdd:PRK11607 169 KLLLLDEPMGALDKKLRDRMQLEVVDILERVGVTCVMVTHDqEEAMTMAGRIAIMNRGK 227
|
|
| ABCG_EPDR |
cd03213 |
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ... |
10-229 |
9.84e-33 |
|
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.
Pssm-ID: 213180 [Multi-domain] Cd Length: 194 Bit Score: 118.04 E-value: 9.84e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 10 VILEANKIRKSYGNKLNKQ--EVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLS---SIDQVShGTIHINGNDMTamke 84
Cdd:cd03213 2 VTLSFRNLTVTVKSSPSKSgkQLLKNVSGKAKPGELTAIMGPSGAGKSTLLNALAgrrTGLGVS-GEVLINGRPLD---- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 85 kqLAEFRKQhLGFIFQDYNLLDTLTVKENILLPLsitklskkeanrkfeevakelgiyELRDkypneISGGQKQRTSAGR 164
Cdd:cd03213 77 --KRSFRKI-IGYVPQDDILHPTLTVRETLMFAA------------------------KLRG-----LSGGERKRVSIAL 124
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
8G4D_C 165 AFIHDPSIIFADEPTGALDSKSASDLLNKLSQLNQkRNATIIMVTHDPVAASY--CGRVIFIKDGQM 229
Cdd:cd03213 125 ELVSNPSLLFLDEPTSGLDSSSALQVMSLLRRLAD-TGRTIICSIHQPSSEIFelFDKLLLLSQGRV 190
|
|
| AppF |
COG4608 |
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ... |
10-211 |
1.39e-32 |
|
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443658 [Multi-domain] Cd Length: 329 Bit Score: 121.38 E-value: 1.39e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 10 VILEANKIRKSY---GNKLNKQ-EVLK---GIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAM 82
Cdd:COG4608 6 PLLEVRDLKKHFpvrGGLFGRTvGVVKavdGVSFDIRRGETLGLVGESGCGKSTLGRLLLRLEEPTSGEILFDGQDITGL 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 83 KEKQLAEFRKqHLGFIFQD-YNLLDT-LTVKENILLPLSI-TKLSKKEANRKFEEVAKELGiyeLR----DKYPNEISGG 155
Cdd:COG4608 86 SGRELRPLRR-RMQMVFQDpYASLNPrMTVGDIIAEPLRIhGLASKAERRERVAELLELVG---LRpehaDRYPHEFSGG 161
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
8G4D_C 156 QKQRTSAGRAFIHDPSIIFADEPTGALD-SKSASdLLNKLSQLNQKRNATIIMVTHD 211
Cdd:COG4608 162 QRQRIGIARALALNPKLIVCDEPVSALDvSIQAQ-VLNLLEDLQDELGLTYLFISHD 217
|
|
| ABCC_bacteriocin_exporters |
cd03245 |
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ... |
27-229 |
3.85e-32 |
|
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.
Pssm-ID: 213212 [Multi-domain] Cd Length: 220 Bit Score: 117.31 E-value: 3.85e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 27 KQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMtamkeKQL--AEFRkQHLGFIFQDYNL 104
Cdd:cd03245 16 EIPALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLDGTDI-----RQLdpADLR-RNIGYVPQDVTL 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 105 LDTlTVKENILLPLSITKlskkeaNRKFEEVAKELGIYELRDKYPN-----------EISGGQKQRTSAGRAFIHDPSII 173
Cdd:cd03245 90 FYG-TLRDNITLGAPLAD------DERILRAAELAGVTDFVNKHPNgldlqigergrGLSGGQRQAVALARALLNDPPIL 162
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
8G4D_C 174 FADEPTGALDSKSASDLLNKLSQLnqKRNATIIMVTHDPVAASYCGRVIFIKDGQM 229
Cdd:cd03245 163 LLDEPTSAMDMNSEERLKERLRQL--LGDKTLIIITHRPSLLDLVDRIIVMDSGRI 216
|
|
| YnjD |
COG4136 |
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ... |
25-222 |
7.24e-32 |
|
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];
Pssm-ID: 443311 [Multi-domain] Cd Length: 211 Bit Score: 116.43 E-value: 7.24e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 25 LNKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNV----LSSIDQVShGTIHINGNDMTAMKekqlAEFRkqHLGFIFQ 100
Cdd:COG4136 11 LGGRPLLAPLSLTVAPGEILTLMGPSGSGKSTLLAAiagtLSPAFSAS-GEVLLNGRRLTALP----AEQR--RIGILFQ 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 101 DYNLLDTLTVKENIL--LPLSITKLSKKEAnrkFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPSIIFADEP 178
Cdd:COG4136 84 DDLLFPHLSVGENLAfaLPPTIGRAQRRAR---VEQALEEAGLAGFADRDPATLSGGQRARVALLRALLAEPRALLLDEP 160
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
8G4D_C 179 TGALDsksaSDLLNKLSQL--NQKRNATI--IMVTHDPVAASYCGRVI 222
Cdd:COG4136 161 FSKLD----AALRAQFREFvfEQIRQRGIpaLLVTHDEEDAPAAGRVL 204
|
|
| ABCC_Glucan_exporter_like |
cd03254 |
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ... |
26-227 |
1.12e-31 |
|
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213221 [Multi-domain] Cd Length: 229 Bit Score: 116.56 E-value: 1.12e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 26 NKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLaefrKQHLGFIFQDYNLL 105
Cdd:cd03254 14 EKKPVLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQILIDGIDIRDISRKSL----RSMIGVVLQDTFLF 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 106 DTlTVKENIllplsitKLSKKEANRK-FEEVAKELGIYELRDKYPN-----------EISGGQKQRTSAGRAFIHDPSII 173
Cdd:cd03254 90 SG-TIMENI-------RLGRPNATDEeVIEAAKEAGAHDFIMKLPNgydtvlgenggNLSQGERQLLAIARAMLRDPKIL 161
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
8G4D_C 174 FADEPTGALDSKSASDLLNKLSQLNQKRnaTIIMVTHDPVAASYCGRVIFIKDG 227
Cdd:cd03254 162 ILDEATSNIDTETEKLIQEALEKLMKGR--TSIIIAHRLSTIKNADKILVLDDG 213
|
|
| 3a01204 |
TIGR00955 |
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ... |
15-228 |
1.29e-31 |
|
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273361 [Multi-domain] Cd Length: 617 Bit Score: 122.46 E-value: 1.29e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 15 NKIRKSYGNKLNKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSID----QVShGTIHINGNDMTAMKEKQLAef 90
Cdd:TIGR00955 25 SRLRGCFCRERPRKHLLKNVSGVAKPGELLAVMGSSGAGKTTLMNALAFRSpkgvKGS-GSVLLNGMPIDAKEMRAIS-- 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 91 rkqhlGFIFQDYNLLDTLTVKENIL------LPLSITKLSKKEAnrkFEEVAKELGIYELRDK---YPNE---ISGGQKQ 158
Cdd:TIGR00955 102 -----AYVQQDDLFIPTLTVREHLMfqahlrMPRRVTKKEKRER---VDEVLQALGLRKCANTrigVPGRvkgLSGGERK 173
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
8G4D_C 159 RTSAGRAFIHDPSIIFADEPTGALDSKSASDLLNKLSQLNQKRNaTIIMVTHDPVAASYC--GRVIFIKDGQ 228
Cdd:TIGR00955 174 RLAFASELLTDPPLLFCDEPTSGLDSFMAYSVVQVLKGLAQKGK-TIICTIHQPSSELFElfDKIILMAEGR 244
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
11-229 |
2.43e-31 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 120.94 E-value: 2.43e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 11 ILEANKIRKSYGNKLNKQEVLKGIDIHIEKGEFVSIMGASGSGKT----TLLNVLSSIDQVSHGTIHINGNDMTAMKEKQ 86
Cdd:COG4172 6 LLSVEDLSVAFGQGGGTVEAVKGVSFDIAAGETLALVGESGSGKSvtalSILRLLPDPAAHPSGSILFDGQDLLGLSERE 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 87 LAEFRKQHLGFIFQD----YNLLdtLTVKENILLPLSI-TKLSKKEANRKFEEVAKELGIYELR---DKYPNEISGGQKQ 158
Cdd:COG4172 86 LRRIRGNRIAMIFQEpmtsLNPL--HTIGKQIAEVLRLhRGLSGAAARARALELLERVGIPDPErrlDAYPHQLSGGQRQ 163
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
8G4D_C 159 RTSAGRAFIHDPSIIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHD-PVAASYCGRVIFIKDGQM 229
Cdd:COG4172 164 RVMIAMALANEPDLLIADEPTTALDVTVQAQILDLLKDLQRELGMALLLITHDlGVVRRFADRVAVMRQGEI 235
|
|
| LptB |
COG1137 |
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ... |
11-190 |
2.49e-31 |
|
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440752 [Multi-domain] Cd Length: 240 Bit Score: 115.90 E-value: 2.49e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 11 ILEANKIRKSYGnklnKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAmkekqLAEF 90
Cdd:COG1137 3 TLEAENLVKSYG----KRTVVKDVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGRIFLDGEDITH-----LPMH 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 91 RKQHLGF--------IFQDynlldtLTVKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSA 162
Cdd:COG1137 74 KRARLGIgylpqeasIFRK------LTVEDNILAVLELRKLSKKEREERLEELLEEFGITHLRKSKAYSLSGGERRRVEI 147
|
170 180
....*....|....*....|....*...
8G4D_C 163 GRAFIHDPSIIFADEPTGALDSKSASDL 190
Cdd:COG1137 148 ARALATNPKFILLDEPFAGVDPIAVADI 175
|
|
| ABC_putative_ATPase |
cd03269 |
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ... |
12-229 |
4.63e-31 |
|
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213236 [Multi-domain] Cd Length: 210 Bit Score: 114.30 E-value: 4.63e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 12 LEANKIRKSYGNKlnkqEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKekqlaefr 91
Cdd:cd03269 1 LEVENVTKRFGRV----TALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFDGKPLDIAA-------- 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 92 KQHLGFIFQDYNLLDTLTVKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPS 171
Cdd:cd03269 69 RNRIGYLPEERGLYPKMKVIDQLVYLAQLKGLKKEEARRRIDEWLERLELSEYANKRVEELSKGNQQKVQFIAAVIHDPE 148
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 172 IIFADEPTGALDSKSASDLLNKLSQLnQKRNATIIMVTH--DPVAAsYCGRVIFIKDGQM 229
Cdd:cd03269 149 LLILDEPFSGLDPVNVELLKDVIREL-ARAGKTVILSTHqmELVEE-LCDRVLLLNKGRA 206
|
|
| modC_ABC |
TIGR02142 |
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ... |
34-229 |
6.09e-31 |
|
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]
Pssm-ID: 131197 [Multi-domain] Cd Length: 354 Bit Score: 117.52 E-value: 6.09e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 34 IDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLAEFRKQHLGFIFQDYNLLDTLTVKEN 113
Cdd:TIGR02142 16 ADFTLPGQGVTAIFGRSGSGKTTLIRLIAGLTRPDEGEIVLNGRTLFDSRKGIFLPPEKRRIGYVFQEARLFPHLSVRGN 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 114 ilLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPSIIFADEPTGALDSKSASDLLNK 193
Cdd:TIGR02142 96 --LRYGMKRARPSERRISFERVIELLGIGHLLGRLPGRLSGGEKQRVAIGRALLSSPRLLLMDEPLAALDDPRKYEILPY 173
|
170 180 190
....*....|....*....|....*....|....*..
8G4D_C 194 LSQLNQKRNATIIMVTHDPV-AASYCGRVIFIKDGQM 229
Cdd:TIGR02142 174 LERLHAEFGIPILYVSHSLQeVLRLADRVVVLEDGRV 210
|
|
| cbiO |
PRK13647 |
cobalt transporter ATP-binding subunit; Provisional |
29-232 |
7.14e-31 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237457 [Multi-domain] Cd Length: 274 Bit Score: 115.60 E-value: 7.14e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 29 EVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKqlaEFRKQhLGFIFQDYNllDTL 108
Cdd:PRK13647 19 KALKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGRVKVMGREVNAENEK---WVRSK-VGLVFQDPD--DQV 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 109 ---TVKENILL-PLSItKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPSIIFADEPTGALDS 184
Cdd:PRK13647 93 fssTVWDDVAFgPVNM-GLDKDEVERRVEEALKAVRMWDFRDKPPYHLSYGQKKRVAIAGVLAMDPDVIVLDEPMAYLDP 171
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
8G4D_C 185 KSASDLLNKLSQLNQkRNATIIMVTHD-PVAASYCGRVIFIKDGQMYTQ 232
Cdd:PRK13647 172 RGQETLMEILDRLHN-QGKTVIVATHDvDLAAEWADQVIVLKEGRVLAE 219
|
|
| ModF |
COG1119 |
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ... |
11-232 |
7.67e-31 |
|
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];
Pssm-ID: 440736 [Multi-domain] Cd Length: 250 Bit Score: 114.80 E-value: 7.67e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 11 ILEANKIRKSYGNKlnkqEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSS-IDQVSHGTIHINGNDMTAMkekQLAE 89
Cdd:COG1119 3 LLELRNVTVRRGGK----TILDDISWTVKPGEHWAILGPNGAGKSTLLSLITGdLPPTYGNDVRLFGERRGGE---DVWE 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 90 FRKqHLGFI---FQDYnLLDTLTVKENIL--------LPLSITKLSKKEAnrkfEEVAKELGIYELRDKYPNEISGGQKQ 158
Cdd:COG1119 76 LRK-RIGLVspaLQLR-FPRDETVLDVVLsgffdsigLYREPTDEQRERA----RELLELLGLAHLADRPFGTLSQGEQR 149
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
8G4D_C 159 RTSAGRAFIHDPSIIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTH--DPVAASYcGRVIFIKDGQMYTQ 232
Cdd:COG1119 150 RVLIARALVKDPELLILDEPTAGLDLGARELLLALLDKLAAEGAPTLVLVTHhvEEIPPGI-THVLLLKDGRVVAA 224
|
|
| ABC_TM1139_LivF_branched |
cd03224 |
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ... |
12-208 |
7.75e-31 |
|
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.
Pssm-ID: 213191 [Multi-domain] Cd Length: 222 Bit Score: 114.07 E-value: 7.75e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 12 LEANKIRKSYGnklnKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLAefr 91
Cdd:cd03224 1 LEVENLNAGYG----KSQILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFDGRDITGLPPHERA--- 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 92 KQHLGFIFQDYNLLDTLTVKENILLPLSItkLSKKEANRKFEEVakelgiYEL-------RDKYPNEISGGQKQRTSAGR 164
Cdd:cd03224 74 RAGIGYVPEGRRIFPELTVEENLLLGAYA--RRRAKRKARLERV------YELfprlkerRKQLAGTLSGGEQQMLAIAR 145
|
170 180 190 200
....*....|....*....|....*....|....*....|....
8G4D_C 165 AFIHDPSIIFADEPTGALDSKSASDLLNKLSQLNqKRNATIIMV 208
Cdd:cd03224 146 ALMSRPKLLLLDEPSEGLAPKIVEEIFEAIRELR-DEGVTILLV 188
|
|
| ModC |
COG4148 |
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ... |
12-229 |
7.97e-31 |
|
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis
Pssm-ID: 443319 [Multi-domain] Cd Length: 358 Bit Score: 117.12 E-value: 7.97e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 12 LEANkIRKSYGN-KLNkqevlkgIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQlaeF 90
Cdd:COG4148 3 LEVD-FRLRRGGfTLD-------VDFTLPGRGVTALFGPSGSGKTTLLRAIAGLERPDSGRIRLGGEVLQDSARGI---F 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 91 RKQH---LGFIFQDYNLLDTLTVKENILLPLSITKlsKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFI 167
Cdd:COG4148 72 LPPHrrrIGYVFQEARLFPHLSVRGNLLYGRKRAP--RAERRISFDEVVELLGIGHLLDRRPATLSGGERQRVAIGRALL 149
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
8G4D_C 168 HDPSIIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHDP--VA--ASycgRVIFIKDGQM 229
Cdd:COG4148 150 SSPRLLLMDEPLAALDLARKAEILPYLERLRDELDIPILYVSHSLdeVArlAD---HVVLLEQGRV 212
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
10-229 |
8.13e-31 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 119.35 E-value: 8.13e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 10 VILEANKIRKSY-GNKlnkqeVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGndmtamKEKQL- 87
Cdd:COG1129 3 PLLEMRGISKSFgGVK-----ALDGVSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDSGEILLDG------EPVRFr 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 88 --AEFRKQHLGFIFQDYNLLDTLTVKENILLPLSITK---LSKKEANRKFEEVAKELGIyELRdkyPN----EISGGQKQ 158
Cdd:COG1129 72 spRDAQAAGIAIIHQELNLVPNLSVAENIFLGREPRRgglIDWRAMRRRARELLARLGL-DID---PDtpvgDLSVAQQQ 147
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
8G4D_C 159 RTSAGRAFIHDPSIIFADEPTGALDSKSASDLLNKLSQLnQKRNATIIMVTH--DPVAAsYCGRVIFIKDGQM 229
Cdd:COG1129 148 LVEIARALSRDARVLILDEPTASLTEREVERLFRIIRRL-KAQGVAIIYISHrlDEVFE-IADRVTVLRDGRL 218
|
|
| ABC_NatA_like |
cd03267 |
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ... |
29-227 |
8.22e-31 |
|
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.
Pssm-ID: 213234 [Multi-domain] Cd Length: 236 Bit Score: 114.35 E-value: 8.22e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 29 EVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDmtamKEKQLAEFRKQhLGFIF-QDYNLLDT 107
Cdd:cd03267 35 EALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVRVAGLV----PWKRRKKFLRR-IGVVFgQKTQLWWD 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 108 LTVKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPSIIFADEPTGALDSKSA 187
Cdd:cd03267 110 LPVIDSFYLLAAIYDLPPARFKKRLDELSELLDLEELLDTPVRQLSLGQRMRAEIAAALLHEPEILFLDEPTIGLDVVAQ 189
|
170 180 190 200
....*....|....*....|....*....|....*....|..
8G4D_C 188 SDLLNKLSQLNQKRNATIIMVTHD--PVAAsYCGRVIFIKDG 227
Cdd:cd03267 190 ENIRNFLKEYNRERGTTVLLTSHYmkDIEA-LARRVLVIDKG 230
|
|
| type_I_sec_PrtD |
TIGR01842 |
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in ... |
27-229 |
1.11e-30 |
|
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 200134 [Multi-domain] Cd Length: 544 Bit Score: 119.37 E-value: 1.11e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 27 KQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLAEfrkqHLGFIFQDYNLLD 106
Cdd:TIGR01842 330 KKPTLRGISFSLQAGEALAIIGPSGSGKSTLARLIVGIWPPTSGSVRLDGADLKQWDRETFGK----HIGYLPQDVELFP 405
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 107 TlTVKENIllplsiTKLSKKEANRKFEEVAKELGIYELRDKYPN-----------EISGGQKQRTSAGRAFIHDPSIIFA 175
Cdd:TIGR01842 406 G-TVAENI------ARFGENADPEKIIEAAKLAGVHELILRLPDgydtvigpggaTLSGGQRQRIALARALYGDPKLVVL 478
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
8G4D_C 176 DEPTGALDSKSASDLLNKLSQLnQKRNATIIMVTHDPVAASYCGRVIFIKDGQM 229
Cdd:TIGR01842 479 DEPNSNLDEEGEQALANAIKAL-KARGITVVVITHRPSLLGCVDKILVLQDGRI 531
|
|
| ABCC_ATM1_transporter |
cd03253 |
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ... |
28-237 |
4.36e-30 |
|
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213220 [Multi-domain] Cd Length: 236 Bit Score: 112.32 E-value: 4.36e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 28 QEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMtamKEKQLAEFRKqHLGFIFQDYNLLDT 107
Cdd:cd03253 14 RPVLKDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSILIDGQDI---REVTLDSLRR-AIGVVPQDTVLFND 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 108 lTVKENIllplsitKLSKKEA-NRKFEEVAKELGIYE----LRDKYPNE-------ISGGQKQRTSAGRAFIHDPSIIFA 175
Cdd:cd03253 90 -TIGYNI-------RYGRPDAtDEEVIEAAKAAQIHDkimrFPDGYDTIvgerglkLSGGEKQRVAIARAILKNPPILLL 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
8G4D_C 176 DEPTGALDSKSASDLLNKLSQLNQKRnaTIIMVTHDPVAASYCGRVIFIKDGQMYTQ------LNKGG 237
Cdd:cd03253 162 DEATSALDTHTEREIQAALRDVSKGR--TTIVIAHRLSTIVNADKIIVLKDGRIVERgtheelLAKGG 227
|
|
| ArpD |
COG4618 |
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ... |
27-229 |
4.65e-30 |
|
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 443660 [Multi-domain] Cd Length: 563 Bit Score: 117.54 E-value: 4.65e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 27 KQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLAefrkQHLGFIFQDYNLLD 106
Cdd:COG4618 344 KRPILRGVSFSLEPGEVLGVIGPSGSGKSTLARLLVGVWPPTAGSVRLDGADLSQWDREELG----RHIGYLPQDVELFD 419
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 107 TlTVKENI-LLPlsitklskkEAN-RKFEEVAKELGIYE----LRDKYPNEI-------SGGQKQRTSAGRAFIHDPSII 173
Cdd:COG4618 420 G-TIAENIaRFG---------DADpEKVVAAAKLAGVHEmilrLPDGYDTRIgeggarlSGGQRQRIGLARALYGDPRLV 489
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
8G4D_C 174 FADEPTGALDSKSASDLLNKLSQLnQKRNATIIMVTHDPVAASYCGRVIFIKDGQM 229
Cdd:COG4618 490 VLDEPNSNLDDEGEAALAAAIRAL-KARGATVVVITHRPSLLAAVDKLLVLRDGRV 544
|
|
| PRK13651 |
PRK13651 |
cobalt transporter ATP-binding subunit; Provisional |
12-229 |
5.34e-30 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184210 [Multi-domain] Cd Length: 305 Bit Score: 114.03 E-value: 5.34e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 12 LEANKIRKSYGNKLNKQ-EVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTI-----HINGNDMTAMKE- 84
Cdd:PRK13651 3 IKVKNIVKIFNKKLPTElKALDNVSVEINQGEFIAIIGQTGSGKTTFIEHLNALLLPDTGTIewifkDEKNKKKTKEKEk 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 85 ---------------KQLAEFRKQhLGFIFQ--DYNLLDTLTVKENILLPLSItKLSKKEANRKFEEVAKELGIYE-LRD 146
Cdd:PRK13651 83 vleklviqktrfkkiKKIKEIRRR-VGVVFQfaEYQLFEQTIEKDIIFGPVSM-GVSKEEAKKRAAKYIELVGLDEsYLQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 147 KYPNEISGGQKQRTSAGRAFIHDPSIIFADEPTGALDSKSASDLLNKLSQLNQKrNATIIMVTHD-PVAASYCGRVIFIK 225
Cdd:PRK13651 161 RSPFELSGGQKRRVALAGILAMEPDFLVFDEPTAGLDPQGVKEILEIFDNLNKQ-GKTIILVTHDlDNVLEWTKRTIFFK 239
|
....
8G4D_C 226 DGQM 229
Cdd:PRK13651 240 DGKI 243
|
|
| PRK14247 |
PRK14247 |
phosphate ABC transporter ATP-binding protein; Provisional |
12-229 |
6.51e-30 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172735 [Multi-domain] Cd Length: 250 Bit Score: 112.31 E-value: 6.51e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 12 LEANKIRKSYGNKlnkqEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVS-----HGTIHINGNDMTAMkekQ 86
Cdd:PRK14247 4 IEIRDLKVSFGQV----EVLDGVNLEIPDNTITALMGPSGSGKSTLLRVFNRLIELYpearvSGEVYLDGQDIFKM---D 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 87 LAEFRKQhLGFIFQDYNLLDTLTVKENILLPLSITKL--SKKEANRKFEEVAKELGIY-ELRDKY---PNEISGGQKQRT 160
Cdd:PRK14247 77 VIELRRR-VQMVFQIPNPIPNLSIFENVALGLKLNRLvkSKKELQERVRWALEKAQLWdEVKDRLdapAGKLSGGQQQRL 155
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 161 SAGRAFIHDPSIIFADEPTGALDSKSASDLLNKLSQLnqKRNATIIMVTHDPVAASYCGR-VIFIKDGQM 229
Cdd:PRK14247 156 CIARALAFQPEVLLADEPTANLDPENTAKIESLFLEL--KKDMTIVLVTHFPQQAARISDyVAFLYKGQI 223
|
|
| cbiO |
PRK13648 |
cobalt transporter ATP-binding subunit; Provisional |
31-232 |
1.42e-29 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184207 [Multi-domain] Cd Length: 269 Bit Score: 112.15 E-value: 1.42e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 31 LKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAmkeKQLAEFRKqHLGFIFQD-YNLLDTLT 109
Cdd:PRK13648 25 LKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIFYNNQAITD---DNFEKLRK-HIGIVFQNpDNQFVGSI 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 110 VKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPSIIFADEPTGALDSKSASD 189
Cdd:PRK13648 101 VKYDVAFGLENHAVPYDEMHRRVSEALKQVDMLERADYEPNALSGGQKQRVAIAGVLALNPSVIILDEATSMLDPDARQN 180
|
170 180 190 200
....*....|....*....|....*....|....*....|...
8G4D_C 190 LLNKLSQLNQKRNATIIMVTHDPVAASYCGRVIFIKDGQMYTQ 232
Cdd:PRK13648 181 LLDLVRKVKSEHNITIISITHDLSEAMEADHVIVMNKGTVYKE 223
|
|
| cbiO |
PRK13634 |
cobalt transporter ATP-binding subunit; Provisional |
31-243 |
1.87e-29 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237454 [Multi-domain] Cd Length: 290 Bit Score: 112.04 E-value: 1.87e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 31 LKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTA-MKEKQLAEFRKqHLGFIFQ--DYNLLDT 107
Cdd:PRK13634 23 LYDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVTIGERVITAgKKNKKLKPLRK-KVGIVFQfpEHQLFEE 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 108 lTVKENILL-PLSItKLSKKEANRKFEEVAKELGIYE-LRDKYPNEISGGQKQRTSAGRAFIHDPSIIFADEPTGALDSK 185
Cdd:PRK13634 102 -TVEKDICFgPMNF-GVSEEDAKQKAREMIELVGLPEeLLARSPFELSGGQMRRVAIAGVLAMEPEVLVLDEPTAGLDPK 179
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
8G4D_C 186 SASDLLNKLSQLNQKRNATIIMVTH---DpvAASYCGRVIFIKDGQMYTQlnkgGQDRQTF 243
Cdd:PRK13634 180 GRKEMMEMFYKLHKEKGLTTVLVTHsmeD--AARYADQIVVMHKGTVFLQ----GTPREIF 234
|
|
| ABC_MTABC3_MDL1_MDL2 |
cd03249 |
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ... |
28-228 |
4.37e-29 |
|
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.
Pssm-ID: 213216 [Multi-domain] Cd Length: 238 Bit Score: 109.94 E-value: 4.37e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 28 QEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMtamKEKQLAEFRKQhLGFIFQDYNLLDT 107
Cdd:cd03249 16 VPILKGLSLTIPPGKTVALVGSSGCGKSTVVSLLERFYDPTSGEILLDGVDI---RDLNLRWLRSQ-IGLVSQEPVLFDG 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 108 lTVKENILLplSITKLSKKEAnrkfEEVAKELGIYELRDKYPN-----------EISGGQKQRTSAGRAFIHDPSIIFAD 176
Cdd:cd03249 92 -TIAENIRY--GKPDATDEEV----EEAAKKANIHDFIMSLPDgydtlvgergsQLSGGQKQRIAIARALLRNPKILLLD 164
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
8G4D_C 177 EPTGALDSKSASDLLNKLSQLnqKRNATIIMVTHDPVAASYCGRVIFIKDGQ 228
Cdd:cd03249 165 EATSALDAESEKLVQEALDRA--MKGRTTIVIAHRLSTIRNADLIAVLQNGQ 214
|
|
| cbiO |
PRK13636 |
cobalt transporter ATP-binding subunit; Provisional |
29-232 |
5.41e-29 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184196 [Multi-domain] Cd Length: 283 Bit Score: 110.71 E-value: 5.41e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 29 EVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTaMKEKQLAEFRkQHLGFIFQDY-NLLDT 107
Cdd:PRK13636 20 HALKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRILFDGKPID-YSRKGLMKLR-ESVGMVFQDPdNQLFS 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 108 LTVKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPSIIFADEPTGALDSKSA 187
Cdd:PRK13636 98 ASVYQDVSFGAVNLKLPEDEVRKRVDNALKRTGIEHLKDKPTHCLSFGQKKRVAIAGVLVMEPKVLVLDEPTAGLDPMGV 177
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
8G4D_C 188 SDLLNKLSQLNQKRNATIIMVTHD-PVAASYCGRVIFIKDGQMYTQ 232
Cdd:PRK13636 178 SEIMKLLVEMQKELGLTIIIATHDiDIVPLYCDNVFVMKEGRVILQ 223
|
|
| CydD |
TIGR02857 |
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ... |
26-222 |
1.37e-28 |
|
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD
Pssm-ID: 274323 [Multi-domain] Cd Length: 529 Bit Score: 113.54 E-value: 1.37e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 26 NKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLaefrKQHLGFIFQDYNLL 105
Cdd:TIGR02857 333 GRRPALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEGSIAVNGVPLADADADSW----RDQIAWVPQHPFLF 408
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 106 DTlTVKENILLPLS-ITKLSKKEANRK--FEEVAKEL--GIYELRDKYPNEISGGQKQRTSAGRAFIHDPSIIFADEPTG 180
Cdd:TIGR02857 409 AG-TIAENIRLARPdASDAEIREALERagLDEFVAALpqGLDTPIGEGGAGLSGGQAQRLALARAFLRDAPLLLLDEPTA 487
|
170 180 190 200
....*....|....*....|....*....|....*....|..
8G4D_C 181 ALDSKSASDLLNKLSQLNQkrNATIIMVTHDPVAASYCGRVI 222
Cdd:TIGR02857 488 HLDAETEAEVLEALRALAQ--GRTVLLVTHRLALAALADRIV 527
|
|
| PRK10070 |
PRK10070 |
proline/glycine betaine ABC transporter ATP-binding protein ProV; |
31-251 |
1.45e-28 |
|
proline/glycine betaine ABC transporter ATP-binding protein ProV;
Pssm-ID: 182221 [Multi-domain] Cd Length: 400 Bit Score: 112.05 E-value: 1.45e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 31 LKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLAEFRKQHLGFIFQDYNLLDTLTV 110
Cdd:PRK10070 44 VKDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGVDIAKISDAELREVRRKKIAMVFQSFALMPHMTV 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 111 KENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPSIIFADEPTGALDSKSASDL 190
Cdd:PRK10070 124 LDNTAFGMELAGINAEERREKALDALRQVGLENYAHSYPDELSGGMRQRVGLARALAINPDILLMDEAFSALDPLIRTEM 203
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
8G4D_C 191 LNKLSQLNQKRNATIIMVTHDPVAASYCG-RVIFIKDGQMYTQ------LNKGGQDR-QTFFQDIMKTQ 251
Cdd:PRK10070 204 QDELVKLQAKHQRTIVFISHDLDEAMRIGdRIAIMQNGEVVQVgtpdeiLNNPANDYvRTFFRGVDISQ 272
|
|
| fbpC |
PRK11432 |
ferric ABC transporter ATP-binding protein; |
12-211 |
2.38e-28 |
|
ferric ABC transporter ATP-binding protein;
Pssm-ID: 183133 [Multi-domain] Cd Length: 351 Bit Score: 110.58 E-value: 2.38e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 12 LEANKIRKSYGnklnKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQlaefr 91
Cdd:PRK11432 7 VVLKNITKRFG----SNTVIDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQIFIDGEDVTHRSIQQ----- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 92 kQHLGFIFQDYNLLDTLTVKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPS 171
Cdd:PRK11432 78 -RDICMVFQSYALFPHMSLGENVGYGLKMLGVPKEERKQRVKEALELVDLAGFEDRYVDQISGGQQQRVALARALILKPK 156
|
170 180 190 200
....*....|....*....|....*....|....*....|
8G4D_C 172 IIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHD 211
Cdd:PRK11432 157 VLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHD 196
|
|
| nikE |
PRK10419 |
nickel ABC transporter ATP-binding protein NikE; |
11-229 |
4.05e-28 |
|
nickel ABC transporter ATP-binding protein NikE;
Pssm-ID: 236689 [Multi-domain] Cd Length: 268 Bit Score: 108.24 E-value: 4.05e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 11 ILEANKIRKSYGN-----KLNKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEK 85
Cdd:PRK10419 3 LLNVSGLSHHYAHgglsgKHQHQTVLNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVSWRGEPLAKLNRA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 86 QLAEFRKQhLGFIFQD----YNllDTLTVKENILLPLS-ITKLSKKEANRKFEEVAKELGI-YELRDKYPNEISGGQKQR 159
Cdd:PRK10419 83 QRKAFRRD-IQMVFQDsisaVN--PRKTVREIIREPLRhLLSLDKAERLARASEMLRAVDLdDSVLDKRPPQLSGGQLQR 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
8G4D_C 160 TSAGRAFIHDPSIIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHD-PVAASYCGRVIFIKDGQM 229
Cdd:PRK10419 160 VCLARALAVEPKLLILDEAVSNLDLVLQAGVIRLLKKLQQQFGTACLFITHDlRLVERFCQRVMVMDNGQI 230
|
|
| PRK15079 |
PRK15079 |
oligopeptide ABC transporter ATP-binding protein OppF; Provisional |
10-211 |
5.29e-28 |
|
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
Pssm-ID: 185037 [Multi-domain] Cd Length: 331 Bit Score: 109.41 E-value: 5.29e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 10 VILEANKIRKSYGNKLNKQ---------EVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMT 80
Cdd:PRK15079 7 VLLEVADLKVHFDIKDGKQwfwqppktlKAVDGVTLRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGEVAWLGKDLL 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 81 AMKEKQLAEFRKQhLGFIFQD--YNLLDTLTVKENILLPLSI--TKLSKKEANRKFEEVAKELGIYE-LRDKYPNEISGG 155
Cdd:PRK15079 87 GMKDDEWRAVRSD-IQMIFQDplASLNPRMTIGEIIAEPLRTyhPKLSRQEVKDRVKAMMLKVGLLPnLINRYPHEFSGG 165
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
8G4D_C 156 QKQRTSAGRAFIHDPSIIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHD 211
Cdd:PRK15079 166 QCQRIGIARALILEPKLIICDEPVSALDVSIQAQVVNLLQQLQREMGLSLIFIAHD 221
|
|
| oppD |
PRK09473 |
oligopeptide transporter ATP-binding component; Provisional |
41-245 |
7.77e-28 |
|
oligopeptide transporter ATP-binding component; Provisional
Pssm-ID: 181888 [Multi-domain] Cd Length: 330 Bit Score: 108.66 E-value: 7.77e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 41 GEFVSIMGASGSGKT----TLLNVLSSIDQVShGTIHINGNDMTAMKEKQLAEFRKQHLGFIFQD--YNLLDTLTVKENI 114
Cdd:PRK09473 42 GETLGIVGESGSGKSqtafALMGLLAANGRIG-GSATFNGREILNLPEKELNKLRAEQISMIFQDpmTSLNPYMRVGEQL 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 115 LLPLSITK-LSKKEAnrkFEEVAKELG---IYELRDK---YPNEISGGQKQRTSAGRAFIHDPSIIFADEPTGALDSKSA 187
Cdd:PRK09473 121 MEVLMLHKgMSKAEA---FEESVRMLDavkMPEARKRmkmYPHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQ 197
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 188 SDLLNKLSQLNQKRNATIIMVTHD-PVAASYCGRVIFikdgqMYT-QLNKGGQDRQTFFQ 245
Cdd:PRK09473 198 AQIMTLLNELKREFNTAIIMITHDlGVVAGICDKVLV-----MYAgRTMEYGNARDVFYQ 252
|
|
| cbiO |
PRK13635 |
energy-coupling factor ABC transporter ATP-binding protein; |
11-232 |
8.87e-28 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184195 [Multi-domain] Cd Length: 279 Bit Score: 107.41 E-value: 8.87e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 11 ILEANKIRKSYGNklNKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGndmTAMKEKQLAEF 90
Cdd:PRK13635 5 IIRVEHISFRYPD--AATYALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTITVGG---MVLSEETVWDV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 91 RKQhLGFIFQ--DYNLLDTlTVKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIH 168
Cdd:PRK13635 80 RRQ-VGMVFQnpDNQFVGA-TVQDDVAFGLENIGVPREEMVERVDQALRQVGMEDFLNREPHRLSGGQKQRVAIAGVLAL 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
8G4D_C 169 DPSIIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHDPVAASYCGRVIFIKDGQMYTQ 232
Cdd:PRK13635 158 QPDIIILDEATSMLDPRGRREVLETVRQLKEQKGITVLSITHDLDEAAQADRVIVMNKGEILEE 221
|
|
| PstB |
COG1117 |
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
1-210 |
9.04e-28 |
|
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440734 [Multi-domain] Cd Length: 258 Bit Score: 107.04 E-value: 9.04e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 1 MSGHHHHHHVILEANKIRKSYGNKlnkqEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVL----SSIDQVSH-GTIHIN 75
Cdd:COG1117 1 MTAPASTLEPKIEVRNLNVYYGDK----QALKDINLDIPENKVTALIGPSGCGKSTLLRCLnrmnDLIPGARVeGEILLD 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 76 GNDMTAmKEKQLAEFRKQhLGFIFQDYNLLdTLTVKENILLPLSIT-KLSKKEANRKFEEVAKELGIY-ELRDK---YPN 150
Cdd:COG1117 77 GEDIYD-PDVDVVELRRR-VGMVFQKPNPF-PKSIYDNVAYGLRLHgIKSKSELDEIVEESLRKAALWdEVKDRlkkSAL 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
8G4D_C 151 EISGGQKQRTSAGRAFIHDPSIIFADEPTGALDSKSAS---DLLNKLsqlnqKRNATIIMVTH 210
Cdd:COG1117 154 GLSGGQQQRLCIARALAVEPEVLLMDEPTSALDPISTAkieELILEL-----KKDYTIVIVTH 211
|
|
| ABCC_MsbA |
cd03251 |
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ... |
30-210 |
1.26e-27 |
|
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213218 [Multi-domain] Cd Length: 234 Bit Score: 106.16 E-value: 1.26e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 30 VLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDmtaMKEKQLAEFRKQhLGFIFQDYNLLDTlT 109
Cdd:cd03251 17 VLRDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDVDSGRILIDGHD---VRDYTLASLRRQ-IGLVSQDVFLFND-T 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 110 VKENILlplsitkLSKKEANRK-FEEVAKELGIYELRDKYPN-----------EISGGQKQRTSAGRAFIHDPSIIFADE 177
Cdd:cd03251 92 VAENIA-------YGRPGATREeVEEAARAANAHEFIMELPEgydtvigergvKLSGGQRQRIAIARALLKDPPILILDE 164
|
170 180 190
....*....|....*....|....*....|...
8G4D_C 178 PTGALDSKSASDLLNKLSQLNQKRnaTIIMVTH 210
Cdd:cd03251 165 ATSALDTESERLVQAALERLMKNR--TTFVIAH 195
|
|
| tauB |
PRK11248 |
taurine ABC transporter ATP-binding subunit; |
11-211 |
1.97e-27 |
|
taurine ABC transporter ATP-binding subunit;
Pssm-ID: 183056 [Multi-domain] Cd Length: 255 Bit Score: 105.94 E-value: 1.97e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 11 ILEANKIRKSYGNKlnkqEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQlaef 90
Cdd:PRK11248 1 MLQISHLYADYGGK----PALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSITLDGKPVEGPGAER---- 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 91 rkqhlGFIFQDYNLLDTLTVKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDP 170
Cdd:PRK11248 73 -----GVVFQNEGLLPWRNVQDNVAFGLQLAGVEKMQRLEIAHQMLKKVGLEGAEKRYIWQLSGGQRQRVGIARALAANP 147
|
170 180 190 200
....*....|....*....|....*....|....*....|.
8G4D_C 171 SIIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHD 211
Cdd:PRK11248 148 QLLLLDEPFGALDAFTREQMQTLLLKLWQETGKQVLLITHD 188
|
|
| PRK14267 |
PRK14267 |
phosphate ABC transporter ATP-binding protein; Provisional |
12-216 |
2.95e-27 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184596 [Multi-domain] Cd Length: 253 Bit Score: 105.69 E-value: 2.95e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 12 LEANKIRKSYGNklnkQEVLKGIDIHIEKGEFVSIMGASGSGKTTLL---NVLSSIDQVS--HGTIHINGNDMTAMKEKQ 86
Cdd:PRK14267 5 IETVNLRVYYGS----NHVIKGVDLKIPQNGVFALMGPSGCGKSTLLrtfNRLLELNEEArvEGEVRLFGRNIYSPDVDP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 87 LaEFRKQhLGFIFQDYNLLDTLTVKENILLPLSITKL--SKKEANRKFEEVAKELGIY-ELRDK---YPNEISGGQKQRT 160
Cdd:PRK14267 81 I-EVRRE-VGMVFQYPNPFPHLTIYDNVAIGVKLNGLvkSKKELDERVEWALKKAALWdEVKDRlndYPSNLSGGQRQRL 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
8G4D_C 161 SAGRAFIHDPSIIFADEPTGALDSKSASDLLNKLSQLnqKRNATIIMVTHDPVAAS 216
Cdd:PRK14267 159 VIARALAMKPKILLMDEPTANIDPVGTAKIEELLFEL--KKEYTIVLVTHSPAQAA 212
|
|
| fecE |
PRK11231 |
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE; |
11-232 |
1.53e-26 |
|
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
Pssm-ID: 183044 [Multi-domain] Cd Length: 255 Bit Score: 103.56 E-value: 1.53e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 11 ILEANKIRKSYGNKlnkqEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLAef 90
Cdd:PRK11231 2 TLRTENLTVGYGTK----RILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDKPISMLSSRQLA-- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 91 rkQHLGFIFQDYNLLDTLTVKENI------LLPLsITKLSKKEaNRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGR 164
Cdd:PRK11231 76 --RRLALLPQHHLTPEGITVRELVaygrspWLSL-WGRLSAED-NARVNQAMEQTRINHLADRRLTDLSGGQRQRAFLAM 151
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
8G4D_C 165 AFIHDPSIIFADEPTGALDSKSASDLLNKLSQLNQKrNATIIMVTHDPVAAS-YCGRVIFIKDGQMYTQ 232
Cdd:PRK11231 152 VLAQDTPVVLLDEPTTYLDINHQVELMRLMRELNTQ-GKTVVTVLHDLNQASrYCDHLVVLANGHVMAQ 219
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
30-243 |
1.55e-26 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 107.48 E-value: 1.55e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 30 VLKGIDIHIEKGEFVSIMGASGSGKTT----LLNVLSSidqvsHGTIHINGNDMTAMKEKQLAEFRKQhLGFIFQDYN-- 103
Cdd:PRK15134 301 VVKNISFTLRPGETLGLVGESGSGKSTtglaLLRLINS-----QGEIWFDGQPLHNLNRRQLLPVRHR-IQVVFQDPNss 374
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 104 LLDTLTVKENILLPLSI--TKLSKKEANRKFEEVAKELGI-YELRDKYPNEISGGQKQRTSAGRAFIHDPSIIFADEPTG 180
Cdd:PRK15134 375 LNPRLNVLQIIEEGLRVhqPTLSAAQREQQVIAVMEEVGLdPETRHRYPAEFSGGQRQRIAIARALILKPSLIILDEPTS 454
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
8G4D_C 181 ALDSKSASDLLNKLSQLNQKRNATIIMVTHD-PVAASYCGRVIFIKDGQMYTQlnkgGQDRQTF 243
Cdd:PRK15134 455 SLDKTVQAQILALLKSLQQKHQLAYLFISHDlHVVRALCHQVIVLRQGEVVEQ----GDCERVF 514
|
|
| LivF |
COG0410 |
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ... |
11-208 |
1.58e-26 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];
Pssm-ID: 440179 [Multi-domain] Cd Length: 236 Bit Score: 103.14 E-value: 1.58e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 11 ILEANKIRKSYGnklnKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLAef 90
Cdd:COG0410 3 MLEVENLHAGYG----GIHVLHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPRSGSIRFDGEDITGLPPHRIA-- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 91 rKQHLGFIFQDYNLLDTLTVKENILLPLSITKlSKKEANRKFEEVakelgiYEL-------RDKYPNEISGGQKQRTSAG 163
Cdd:COG0410 77 -RLGIGYVPEGRRIFPSLTVEENLLLGAYARR-DRAEVRADLERV------YELfprlkerRRQRAGTLSGGEQQMLAIG 148
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
8G4D_C 164 RAFIHDPSIIFADEPTGALDSKSASDLLNKLSQLNQkRNATIIMV 208
Cdd:COG0410 149 RALMSRPKLLLLDEPSLGLAPLIVEEIFEIIRRLNR-EGVTILLV 192
|
|
| type_I_sec_LssB |
TIGR03375 |
type I secretion system ATPase, LssB family; Type I protein secretion is a system in some ... |
26-228 |
4.73e-26 |
|
type I secretion system ATPase, LssB family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. This model is related to models TIGR01842 and TIGR01846, and to bacteriocin ABC transporters that cleave their substrates during export. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]
Pssm-ID: 274550 [Multi-domain] Cd Length: 694 Bit Score: 106.49 E-value: 4.73e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 26 NKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTamkekQL--AEFRkQHLGFIFQDYN 103
Cdd:TIGR03375 476 QETPALDNVSLTIRPGEKVAIIGRIGSGKSTLLKLLLGLYQPTEGSVLLDGVDIR-----QIdpADLR-RNIGYVPQDPR 549
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 104 LLdTLTVKENILLplsitklskkeANRKFE-----EVAKELGIYELRDKYPN-----------EISGGQKQRTSAGRAFI 167
Cdd:TIGR03375 550 LF-YGTLRDNIAL-----------GAPYADdeeilRAAELAGVTEFVRRHPDgldmqigergrSLSGGQRQAVALARALL 617
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
8G4D_C 168 HDPSIIFADEPTGALDSKSASDLLNKLSQLNQKRnaTIIMVTHDPVAASYCGRVIFIKDGQ 228
Cdd:TIGR03375 618 RDPPILLLDEPTSAMDNRSEERFKDRLKRWLAGK--TLVLVTHRTSLLDLVDRIIVMDNGR 676
|
|
| PRK13633 |
PRK13633 |
energy-coupling factor transporter ATPase; |
30-252 |
5.83e-26 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237453 [Multi-domain] Cd Length: 280 Bit Score: 102.86 E-value: 5.83e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 30 VLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTamKEKQLAEFRkQHLGFIFQ--DYNLLDT 107
Cdd:PRK13633 25 ALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKVYVDGLDTS--DEENLWDIR-NKAGMVFQnpDNQIVAT 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 108 LtVKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTS-AGRAFIHDPSIIFaDEPTGALDSKS 186
Cdd:PRK13633 102 I-VEEDVAFGPENLGIPPEEIRERVDESLKKVGMYEYRRHAPHLLSGGQKQRVAiAGILAMRPECIIF-DEPTAMLDPSG 179
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
8G4D_C 187 ASDLLNKLSQLNQKRNATIIMVTHDPVAASYCGRVIFIKDGQMYtqlnKGGQDRQTFFQ-DIMKTQG 252
Cdd:PRK13633 180 RREVVNTIKELNKKYGITIILITHYMEEAVEADRIIVMDSGKVV----MEGTPKEIFKEvEMMKKIG 242
|
|
| CydC |
TIGR02868 |
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ... |
28-212 |
6.78e-26 |
|
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.
Pssm-ID: 274331 [Multi-domain] Cd Length: 530 Bit Score: 105.91 E-value: 6.78e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 28 QEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLAefrkQHLGFIFQDYNLLDT 107
Cdd:TIGR02868 348 PPVLDGVSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPLQGEVTLDGVPVSSLDQDEVR----RRVSVCAQDAHLFDT 423
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 108 lTVKENILlpLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEI-------SGGQKQRTSAGRAFIHDPSIIFADEPTG 180
Cdd:TIGR02868 424 -TVRENLR--LARPDATDEELWAALERVGLADWLRALPDGLDTVLgeggarlSGGERQRLALARALLADAPILLLDEPTE 500
|
170 180 190
....*....|....*....|....*....|..
8G4D_C 181 ALDSKSASDLLNKLSQLNQKRnaTIIMVTHDP 212
Cdd:TIGR02868 501 HLDAETADELLEDLLAALSGR--TVVLITHHL 530
|
|
| ABCC_cytochrome_bd |
cd03247 |
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ... |
12-228 |
7.45e-26 |
|
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.
Pssm-ID: 213214 [Multi-domain] Cd Length: 178 Bit Score: 99.69 E-value: 7.45e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 12 LEANKIRKSYGNklNKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKqlaefR 91
Cdd:cd03247 1 LSINNVSFSYPE--QEQQVLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGEITLDGVPVSDLEKA-----L 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 92 KQHLGFIFQDYNLLDTlTVKENILLPLSitklskkeanrkfeevakelgiyelrdkypneisGGQKQRTSAGRAFIHDPS 171
Cdd:cd03247 74 SSLISVLNQRPYLFDT-TLRNNLGRRFS----------------------------------GGERQRLALARILLQDAP 118
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
8G4D_C 172 IIFADEPTGALDSKSASDLLNKLsqLNQKRNATIIMVTHDPVAASYCGRVIFIKDGQ 228
Cdd:cd03247 119 IVLLDEPTVGLDPITERQLLSLI--FEVLKDKTLIWITHHLTGIEHMDKILFLENGK 173
|
|
| PhnL |
COG4778 |
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ... |
30-228 |
1.23e-25 |
|
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];
Pssm-ID: 443809 [Multi-domain] Cd Length: 229 Bit Score: 100.59 E-value: 1.23e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 30 VLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGN----DMTAMKEKQLAEFRKQHLGFIFQdynLL 105
Cdd:COG4778 26 VLDGVSFSVAAGECVALTGPSGAGKSTLLKCIYGNYLPDSGSILVRHDggwvDLAQASPREILALRRRTIGYVSQ---FL 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 106 DTL-------TVKEnillPLSITKLSKKEANRKFEEVAKELGIYE-LRDKYPNEISGGQKQRTSAGRAFIHDPSIIFADE 177
Cdd:COG4778 103 RVIprvsaldVVAE----PLLERGVDREEARARARELLARLNLPErLWDLPPATFSGGEQQRVNIARGFIADPPLLLLDE 178
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
8G4D_C 178 PTGALDSKSAS---DLLNKLsqlnQKRNATIIMVTHDP-VAASYCGRVIFIKDGQ 228
Cdd:COG4778 179 PTASLDAANRAvvvELIEEA----KARGTAIIGIFHDEeVREAVADRVVDVTPFS 229
|
|
| cbiO |
PRK13650 |
energy-coupling factor transporter ATPase; |
11-228 |
1.91e-25 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184209 [Multi-domain] Cd Length: 279 Bit Score: 101.35 E-value: 1.91e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 11 ILEANKIRKSYgNKLNKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTamkEKQLAEF 90
Cdd:PRK13650 4 IIEVKNLTFKY-KEDQEKYTLNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIIDGDLLT---EENVWDI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 91 RkQHLGFIFQDY-NLLDTLTVKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHD 169
Cdd:PRK13650 80 R-HKIGMVFQNPdNQFVGATVEDDVAFGLENKGIPHEEMKERVNEALELVGMQDFKEREPARLSGGQKQRVAIAGAVAMR 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
8G4D_C 170 PSIIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHDPVAASYCGRVIFIKDGQ 228
Cdd:PRK13650 159 PKIIILDEATSMLDPEGRLELIKTIKGIRDDYQMTVISITHDLDEVALSDRVLVMKNGQ 217
|
|
| COG4586 |
COG4586 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
29-229 |
3.79e-25 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443643 [Multi-domain] Cd Length: 323 Bit Score: 101.32 E-value: 3.79e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 29 EVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGndMTAMKEKQlaEFRKQhLGFIF-QDYNLLDT 107
Cdd:COG4586 36 EAVDDISFTIEPGEIVGFIGPNGAGKSTTIKMLTGILVPTSGEVRVLG--YVPFKRRK--EFARR-IGVVFgQRSQLWWD 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 108 LTVKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPSIIFADEPTGALD--SK 185
Cdd:COG4586 111 LPAIDSFRLLKAIYRIPDAEYKKRLDELVELLDLGELLDTPVRQLSLGQRMRCELAAALLHRPKILFLDEPTIGLDvvSK 190
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
8G4D_C 186 SAsdLLNKLSQLNQKRNATIIMVTHDP--VAAsYCGRVIFIKDGQM 229
Cdd:COG4586 191 EA--IREFLKEYNRERGTTILLTSHDMddIEA-LCDRVIVIDHGRI 233
|
|
| TagH |
COG1134 |
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ... |
30-229 |
4.06e-25 |
|
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440749 [Multi-domain] Cd Length: 245 Bit Score: 99.77 E-value: 4.06e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 30 VLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNdMTAMKEkqlaefrkqhLGFIFQdynllDTLT 109
Cdd:COG1134 41 ALKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTSGRVEVNGR-VSALLE----------LGAGFH-----PELT 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 110 VKENILLPLSITKLSKKEANRKFEEVAK--ELGIYelRDkypneisggQKQRT-SAG---R-AF---IH-DPSIIFADEP 178
Cdd:COG1134 105 GRENIYLNGRLLGLSRKEIDEKFDEIVEfaELGDF--ID---------QPVKTySSGmraRlAFavaTAvDPDILLVDEV 173
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
8G4D_C 179 TGALDS----KSasdlLNKLSQLnQKRNATIIMVTHDP-VAASYCGRVIFIKDGQM 229
Cdd:COG1134 174 LAVGDAafqkKC----LARIREL-RESGRTVIFVSHSMgAVRRLCDRAIWLEKGRL 224
|
|
| ABC_BcrA_bacitracin_resist |
cd03268 |
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ... |
12-229 |
5.38e-25 |
|
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.
Pssm-ID: 213235 [Multi-domain] Cd Length: 208 Bit Score: 98.44 E-value: 5.38e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 12 LEANKIRKSYGnklnKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKqlaefr 91
Cdd:cd03268 1 LKTNDLTKTYG----KKRVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEITFDGKSYQKNIEA------ 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 92 KQHLGFIFQDYNLLDTLTVKENILLPLSITKLSKKEANRKFEEVakelGIYELRDKYPNEISGGQKQRTSAGRAFIHDPS 171
Cdd:cd03268 71 LRRIGALIEAPGFYPNLTARENLRLLARLLGIRKKRIDEVLDVV----GLKDSAKKKVKGFSLGMKQRLGIALALLGNPD 146
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
8G4D_C 172 IIFADEPTGALDSKSASDLLNKLSQLNqKRNATIIMVTH-----DPVAAsycgRVIFIKDGQM 229
Cdd:cd03268 147 LLILDEPTNGLDPDGIKELRELILSLR-DQGITVLISSHllseiQKVAD----RIGIINKGKL 204
|
|
| ABC_Carb_Monos_I |
cd03216 |
First domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
12-229 |
9.54e-25 |
|
First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213183 [Multi-domain] Cd Length: 163 Bit Score: 96.34 E-value: 9.54e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 12 LEANKIRKSYGNklnkQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDmtamkekqlaefr 91
Cdd:cd03216 1 LELRGITKRFGG----VKALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEILVDGKE------------- 63
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 92 kqhlgfifqdynlldtltvkenillplsITKLSKKEANRkfeevakeLGI---YELrdkypneiSGGQKQRTSAGRAFIH 168
Cdd:cd03216 64 ----------------------------VSFASPRDARR--------AGIamvYQL--------SVGERQMVEIARALAR 99
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
8G4D_C 169 DPSIIFADEPTGALDSKSASDLLNKLSQLnQKRNATIIMVTH--DPVAAsYCGRVIFIKDGQM 229
Cdd:cd03216 100 NARLLILDEPTAALTPAEVERLFKVIRRL-RAQGVAVIFISHrlDEVFE-IADRVTVLRDGRV 160
|
|
| dppF |
PRK11308 |
dipeptide transporter ATP-binding subunit; Provisional |
10-232 |
1.80e-24 |
|
dipeptide transporter ATP-binding subunit; Provisional
Pssm-ID: 236898 [Multi-domain] Cd Length: 327 Bit Score: 99.65 E-value: 1.80e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 10 VILEANKIRKSYGNK--LNKQE----VLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDmTAMK 83
Cdd:PRK11308 4 PLLQAIDLKKHYPVKrgLFKPErlvkALDGVSFTLERGKTLAVVGESGCGKSTLARLLTMIETPTGGELYYQGQD-LLKA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 84 EKQLAEFRKQHLGFIFQD-YNLLDTLTVKENILL-PLSI-TKLSKKEANRKFEEVAKELGIY-ELRDKYPNEISGGQKQR 159
Cdd:PRK11308 83 DPEAQKLLRQKIQIVFQNpYGSLNPRKKVGQILEePLLInTSLSAAERREKALAMMAKVGLRpEHYDRYPHMFSGGQRQR 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 160 TSAGRAFIHDPSIIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTH---------DPVAASYCGRV--------I 222
Cdd:PRK11308 163 IAIARALMLDPDVVVADEPVSALDVSVQAQVLNLMMDLQQELGLSYVFISHdlsvvehiaDEVMVMYLGRCvekgtkeqI 242
|
250
....*....|
8G4D_C 223 FIKDGQMYTQ 232
Cdd:PRK11308 243 FNNPRHPYTQ 252
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
11-229 |
2.02e-24 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 101.26 E-value: 2.02e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 11 ILEANKIRKSYGNKLnkqeVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGndmtamKEKQL--- 87
Cdd:COG3845 5 ALELRGITKRFGGVV----ANDDVSLTVRPGEIHALLGENGAGKSTLMKILYGLYQPDSGEILIDG------KPVRIrsp 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 88 AEFRKQHLGFIFQDYNLLDTLTVKENILL---PLSITKLSKKEANRKFEEVAKELGiyeLR---DKYPNEISGGQKQRTS 161
Cdd:COG3845 75 RDAIALGIGMVHQHFMLVPNLTVAENIVLglePTKGGRLDRKAARARIRELSERYG---LDvdpDAKVEDLSVGEQQRVE 151
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 162 AGRAFIHDPSIIFADEPTGALDSKSASDLLNKLSQLnQKRNATIIMVTH--DPVAAsYCGRVIFIKDGQM 229
Cdd:COG3845 152 ILKALYRGARILILDEPTAVLTPQEADELFEILRRL-AAEGKSIIFITHklREVMA-IADRVTVLRRGKV 219
|
|
| ABCC_MRP_domain1 |
cd03250 |
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ... |
30-228 |
2.27e-24 |
|
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213217 [Multi-domain] Cd Length: 204 Bit Score: 96.77 E-value: 2.27e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 30 VLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGndmtamkekqlaefrkqHLGFIFQDYNLLDTlT 109
Cdd:cd03250 20 TLKDINLEVPKGELVAIVGPVGSGKSSLLSALLGELEKLSGSVSVPG-----------------SIAYVSQEPWIQNG-T 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 110 VKENILLplsitklSKKEANRKFEEVAK------ELGIYELRDKYpnEI-------SGGQKQRTSAGRAFIHDPSIIFAD 176
Cdd:cd03250 82 IRENILF-------GKPFDEERYEKVIKacalepDLEILPDGDLT--EIgekginlSGGQKQRISLARAVYSDADIYLLD 152
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
8G4D_C 177 EPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHDPVAASYCGRVIFIKDGQ 228
Cdd:cd03250 153 DPLSAVDAHVGRHIFENCILGLLLNNKTRILVTHQLQLLPHADQIVVLDNGR 204
|
|
| AztA |
NF040873 |
zinc ABC transporter ATP-binding protein AztA; |
30-216 |
2.41e-24 |
|
zinc ABC transporter ATP-binding protein AztA;
Pssm-ID: 468810 [Multi-domain] Cd Length: 191 Bit Score: 96.15 E-value: 2.41e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 30 VLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDmtamkekqlaefrkqHLGFIFQDYNLLDTL- 108
Cdd:NF040873 7 VLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTVRRAGGA---------------RVAYVPQRSEVPDSLp 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 109 -TVKENILL----PLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPSIIFADEPTGALD 183
Cdd:NF040873 72 lTVRDLVAMgrwaRRGLWRRLTRDDRAAVDDALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLLLDEPTTGLD 151
|
170 180 190
....*....|....*....|....*....|...
8G4D_C 184 SKSASDLLNKLSQLnQKRNATIIMVTHDPVAAS 216
Cdd:NF040873 152 AESRERIIALLAEE-HARGATVVVVTHDLELVR 183
|
|
| nickel_nikD |
TIGR02770 |
nickel import ATP-binding protein NikD; This family represents the NikD subunit of a ... |
33-229 |
2.67e-24 |
|
nickel import ATP-binding protein NikD; This family represents the NikD subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. NikD and NikE are homologous. [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 131817 [Multi-domain] Cd Length: 230 Bit Score: 97.05 E-value: 2.67e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 33 GIDIHIEKGEFVSIMGASGSGKTT----LLNVLSSIDQVSHGTIHINGNDMTAMKekqlaeFRKQHLGFIFQD----YNL 104
Cdd:TIGR02770 4 DLNLSLKRGEVLALVGESGSGKSLtclaILGLLPPGLTQTSGEILLDGRPLLPLS------IRGRHIATIMQNprtaFNP 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 105 LDTLT--VKENILLPLSITKLSKKEANRKFEEVAKELGiYELRDKYPNEISGGQKQRTSAGRAFIHDPSIIFADEPTGAL 182
Cdd:TIGR02770 78 LFTMGnhAIETLRSLGKLSKQARALILEALEAVGLPDP-EEVLKKYPFQLSGGMLQRVMIALALLLEPPFLIADEPTTDL 156
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
8G4D_C 183 DSKSASDLLNKLSQLNQKRNATIIMVTHD-PVAASYCGRVIFIKDGQM 229
Cdd:TIGR02770 157 DVVNQARVLKLLRELRQLFGTGILLITHDlGVVARIADEVAVMDDGRI 204
|
|
| ABCC_Hemolysin |
cd03252 |
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ... |
29-232 |
3.94e-24 |
|
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.
Pssm-ID: 213219 [Multi-domain] Cd Length: 237 Bit Score: 96.79 E-value: 3.94e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 29 EVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMkekQLAEFRKQhLGFIFQDyNLLDTL 108
Cdd:cd03252 16 VILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLVDGHDLALA---DPAWLRRQ-VGVVLQE-NVLFNR 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 109 TVKENILLPLSITKLskkeanRKFEEVAKELG----IYELRDKYPN-------EISGGQKQRTSAGRAFIHDPSIIFADE 177
Cdd:cd03252 91 SIRDNIALADPGMSM------ERVIEAAKLAGahdfISELPEGYDTivgeqgaGLSGGQRQRIAIARALIHNPRILIFDE 164
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
8G4D_C 178 PTGALDSKSASDLLNKLSQLNQKRnaTIIMVTHDPVAASYCGRVIFIKDGQMYTQ 232
Cdd:cd03252 165 ATSALDYESEHAIMRNMHDICAGR--TVIIIAHRLSTVKNADRIIVMEKGRIVEQ 217
|
|
| urea_trans_UrtE |
TIGR03410 |
urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC ... |
12-208 |
4.36e-24 |
|
urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC transporter ATP-binding subunits associated with urea transport and metabolism. This protein is found in a conserved five-gene transport operon typically found adjacent to urease genes. It was shown in Cyanobacteria that disruption leads to the loss of high-affinity urea transport activity. [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 274567 [Multi-domain] Cd Length: 230 Bit Score: 96.44 E-value: 4.36e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 12 LEANKIRKSYGnklnKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLAefr 91
Cdd:TIGR03410 1 LEVSNLNVYYG----QSHILRGVSLEVPKGEVTCVLGRNGVGKTTLLKTLMGLLPVKSGSIRLDGEDITKLPPHERA--- 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 92 KQHLGFIFQDYNLLDTLTVKENILLPLSITKLSKKEanrkfeeVAKElgIYEL-------RDKYPNEISGGQKQRTSAGR 164
Cdd:TIGR03410 74 RAGIAYVPQGREIFPRLTVEENLLTGLAALPRRSRK-------IPDE--IYELfpvlkemLGRRGGDLSGGQQQQLAIAR 144
|
170 180 190 200
....*....|....*....|....*....|....*....|....
8G4D_C 165 AFIHDPSIIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMV 208
Cdd:TIGR03410 145 ALVTRPKLLLLDEPTEGIQPSIIKDIGRVIRRLRAEGGMAILLV 188
|
|
| PRK10253 |
PRK10253 |
iron-enterobactin ABC transporter ATP-binding protein; |
12-232 |
6.64e-24 |
|
iron-enterobactin ABC transporter ATP-binding protein;
Pssm-ID: 182336 [Multi-domain] Cd Length: 265 Bit Score: 96.98 E-value: 6.64e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 12 LEANKIRKSYGNKLnkqeVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLAefr 91
Cdd:PRK10253 8 LRGEQLTLGYGKYT----VAENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLDGEHIQHYASKEVA--- 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 92 kQHLGFIFQDYNLLDTLTVKENIL------LPLsITKLSKKEAnrkfEEVAKEL---GIYELRDKYPNEISGGQKQRTSA 162
Cdd:PRK10253 81 -RRIGLLAQNATTPGDITVQELVArgryphQPL-FTRWRKEDE----EAVTKAMqatGITHLADQSVDTLSGGQRQRAWI 154
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
8G4D_C 163 GRAFIHDPSIIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHD-PVAASYCGRVIFIKDGQMYTQ 232
Cdd:PRK10253 155 AMVLAQETAIMLLDEPTTWLDISHQIDLLELLSELNREKGYTLAAVLHDlNQACRYASHLIALREGKIVAQ 225
|
|
| PRK14246 |
PRK14246 |
phosphate ABC transporter ATP-binding protein; Provisional |
25-229 |
7.70e-24 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172734 [Multi-domain] Cd Length: 257 Bit Score: 96.65 E-value: 7.70e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 25 LNKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEK---QLAEFRKQhLGFIFQD 101
Cdd:PRK14246 20 INDKAILKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLIEIYDSKIKVDGKVLYFGKDIfqiDAIKLRKE-VGMVFQQ 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 102 YNLLDTLTVKENILLPLSITKLS-KKEANRKFEEVAKELGIY-ELRDKY---PNEISGGQKQRTSAGRAFIHDPSIIFAD 176
Cdd:PRK14246 99 PNPFPHLSIYDNIAYPLKSHGIKeKREIKKIVEECLRKVGLWkEVYDRLnspASQLSGGQQQRLTIARALALKPKVLLMD 178
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
8G4D_C 177 EPTGALDSKSASDLLNKLSQLnqKRNATIIMVTHDP-VAASYCGRVIFIKDGQM 229
Cdd:PRK14246 179 EPTSMIDIVNSQAIEKLITEL--KNEIAIVIVSHNPqQVARVADYVAFLYNGEL 230
|
|
| modC |
PRK11144 |
molybdenum ABC transporter ATP-binding protein ModC; |
46-210 |
7.76e-24 |
|
molybdenum ABC transporter ATP-binding protein ModC;
Pssm-ID: 182993 [Multi-domain] Cd Length: 352 Bit Score: 98.41 E-value: 7.76e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 46 IMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLAEFRKQHLGFIFQDYNLLDTLTVKENILLPLsitklsK 125
Cdd:PRK11144 29 IFGRSGAGKTSLINAISGLTRPQKGRIVLNGRVLFDAEKGICLPPEKRRIGYVFQDARLFPHYKVRGNLRYGM------A 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 126 KEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPSIIFADEPTGALDSKSASDLLNKLSQLNQKRNATI 205
Cdd:PRK11144 103 KSMVAQFDKIVALLGIEPLLDRYPGSLSGGEKQRVAIGRALLTAPELLLMDEPLASLDLPRKRELLPYLERLAREINIPI 182
|
....*
8G4D_C 206 IMVTH 210
Cdd:PRK11144 183 LYVSH 187
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
33-229 |
1.67e-23 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 98.72 E-value: 1.67e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 33 GIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHIN-GNDMTAMKEKQLAE--FRKQHLGFIFQDYNLLDTLT 109
Cdd:TIGR03269 302 NVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGEVNVRvGDEWVDMTKPGPDGrgRAKRYIGILHQEYDLYPHRT 381
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 110 VKENILLPLSItKLSKKEANRKFEEVAKELGIYE-----LRDKYPNEISGGQKQRTSAGRAFIHDPSIIFADEPTGALDS 184
Cdd:TIGR03269 382 VLDNLTEAIGL-ELPDELARMKAVITLKMVGFDEekaeeILDKYPDELSEGERHRVALAQVLIKEPRIVILDEPTGTMDP 460
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
8G4D_C 185 KSASDLLNKLSQLNQKRNATIIMVTHD-PVAASYCGRVIFIKDGQM 229
Cdd:TIGR03269 461 ITKVDVTHSILKAREEMEQTFIIVSHDmDFVLDVCDRAALMRDGKI 506
|
|
| CP_lyasePhnK |
TIGR02323 |
phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P ... |
11-229 |
1.98e-23 |
|
phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P lyase systems for utilization of phosphonates. These systems resemble phosphonatase-based systems in having a three component ABC transporter, where TIGR01097 is the permease, TIGR01098 is the phosphonates binding protein, and TIGR02315 is the ATP-binding cassette (ABC) protein. They differ, however, in having, typically, ten or more additional genes, many of which are believed to form a membrane-associated complex. This protein (PhnK) and the adjacent-encoded PhnL resemble transporter ATP-binding proteins but are suggested, based on mutatgenesis studies, to be part of this complex rather than part of a transporter per se. [Central intermediary metabolism, Phosphorus compounds]
Pssm-ID: 188208 [Multi-domain] Cd Length: 253 Bit Score: 95.28 E-value: 1.98e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 11 ILEANKIRKSYGNklnkQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLAEF 90
Cdd:TIGR02323 3 LLQVSGLSKSYGG----GKGCRDVSFDLYPGEVLGIVGESGSGKSTLLGCLAGRLAPDHGTATYIMRSGAELELYQLSEA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 91 RKQHL-----GFIFQdyNLLDTL----TVKENI---LLPLSITKLSK--KEANRKFEEVAKELGIYelrDKYPNEISGGQ 156
Cdd:TIGR02323 79 ERRRLmrtewGFVHQ--NPRDGLrmrvSAGANIgerLMAIGARHYGNirATAQDWLEEVEIDPTRI---DDLPRAFSGGM 153
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
8G4D_C 157 KQRTSAGRAFIHDPSIIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHD-PVAASYCGRVIFIKDGQM 229
Cdd:TIGR02323 154 QQRLQIARNLVTRPRLVFMDEPTGGLDVSVQARLLDLLRGLVRDLGLAVIIVTHDlGVARLLAQRLLVMQQGRV 227
|
|
| cbiO |
PRK13642 |
energy-coupling factor transporter ATPase; |
31-229 |
5.00e-23 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184202 [Multi-domain] Cd Length: 277 Bit Score: 94.77 E-value: 5.00e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 31 LKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLaefrKQHLGFIFQDY-NLLDTLT 109
Cdd:PRK13642 23 LNGVSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGKVKIDGELLTAENVWNL----RRKIGMVFQNPdNQFVGAT 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 110 VKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPSIIFADEPTGALDSKSASD 189
Cdd:PRK13642 99 VEDDVAFGMENQGIPREEMIKRVDEALLAVNMLDFKTREPARLSGGQKQRVAVAGIIALRPEIIILDESTSMLDPTGRQE 178
|
170 180 190 200
....*....|....*....|....*....|....*....|
8G4D_C 190 LLNKLSQLNQKRNATIIMVTHDPVAASYCGRVIFIKDGQM 229
Cdd:PRK13642 179 IMRVIHEIKEKYQLTVLSITHDLDEAASSDRILVMKAGEI 218
|
|
| ABC_KpsT_Wzt |
cd03220 |
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ... |
18-230 |
6.31e-23 |
|
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.
Pssm-ID: 213187 [Multi-domain] Cd Length: 224 Bit Score: 93.37 E-value: 6.31e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 18 RKSYGNKLNKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNdMTAMKEkqlaefrkqhLGF 97
Cdd:cd03220 25 ILGRKGEVGEFWALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTVTVRGR-VSSLLG----------LGG 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 98 IFQdynllDTLTVKENILLPLSITKLSKKEANRKFEEVAK--ELGiyELRDKYPNEISGGQKQRTSAGRAFIHDPSIIFA 175
Cdd:cd03220 94 GFN-----PELTGRENIYLNGRLLGLSRKEIDEKIDEIIEfsELG--DFIDLPVKTYSSGMKARLAFAIATALEPDILLI 166
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
8G4D_C 176 DEPTGALDSKSASDLLNKLSQLnQKRNATIIMVTHDPVA-ASYCGRVIFIKDGQMY 230
Cdd:cd03220 167 DEVLAVGDAAFQEKCQRRLREL-LKQGKTVILVSHDPSSiKRLCDRALVLEKGKIR 221
|
|
| PLN03211 |
PLN03211 |
ABC transporter G-25; Provisional |
30-217 |
8.23e-23 |
|
ABC transporter G-25; Provisional
Pssm-ID: 215634 [Multi-domain] Cd Length: 659 Bit Score: 97.26 E-value: 8.23e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 30 VLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSH--GTIHINGNDMTamkeKQLAefrkQHLGFIFQDYNLLDT 107
Cdd:PLN03211 83 ILNGVTGMASPGEILAVLGPSGSGKSTLLNALAGRIQGNNftGTILANNRKPT----KQIL----KRTGFVTQDDILYPH 154
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 108 LTVKENIL------LPLSitkLSKKEANRKFEEVAKELGIYE-----LRDKYPNEISGGQKQRTSAGRAFIHDPSIIFAD 176
Cdd:PLN03211 155 LTVRETLVfcsllrLPKS---LTKQEKILVAESVISELGLTKcentiIGNSFIRGISGGERKRVSIAHEMLINPSLLILD 231
|
170 180 190 200
....*....|....*....|....*....|....*....|.
8G4D_C 177 EPTGALDSKSASDLLNKLSQLNQKrNATIIMVTHDPVAASY 217
Cdd:PLN03211 232 EPTSGLDATAAYRLVLTLGSLAQK-GKTIVTSMHQPSSRVY 271
|
|
| PRK13537 |
PRK13537 |
nodulation factor ABC transporter ATP-binding protein NodI; |
11-228 |
1.54e-22 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237420 [Multi-domain] Cd Length: 306 Bit Score: 94.10 E-value: 1.54e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 11 ILEANKIRKSYGNKLnkqeVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMtamkeKQLAEF 90
Cdd:PRK13537 7 PIDFRNVEKRYGDKL----VVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLCGEPV-----PSRARH 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 91 RKQHLGFIFQDYNLLDTLTVKENILLPLSITKLSKKEANRKfeeVAKELGIYELRDKYP---NEISGGQKQRTSAGRAFI 167
Cdd:PRK13537 78 ARQRVGVVPQFDNLDPDFTVRENLLVFGRYFGLSAAAARAL---VPPLLEFAKLENKADakvGELSGGMKRRLTLARALV 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
8G4D_C 168 HDPSIIFADEPTGALDSKSASDLLNKLSQLnQKRNATIIMVTH-DPVAASYCGRVIFIKDGQ 228
Cdd:PRK13537 155 NDPDVLVLDEPTTGLDPQARHLMWERLRSL-LARGKTILLTTHfMEEAERLCDRLCVIEEGR 215
|
|
| dppD |
PRK11022 |
dipeptide transporter ATP-binding subunit; Provisional |
11-229 |
3.17e-22 |
|
dipeptide transporter ATP-binding subunit; Provisional
Pssm-ID: 182906 [Multi-domain] Cd Length: 326 Bit Score: 93.65 E-value: 3.17e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 11 ILEANKIRKSYGNKLNKQEVLKGIDIHIEKGEFVSIMGASGSGKT-TLLNVLSSID---QVSHGTIHINGNDMTAMKEKQ 86
Cdd:PRK11022 3 LLNVDKLSVHFGDESAPFRAVDRISYSVKQGEVVGIVGESGSGKSvSSLAIMGLIDypgRVMAEKLEFNGQDLQRISEKE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 87 LAEFRKQHLGFIFQD--YNLLDTLTVKENILLPLSITKL-SKKEANRKFEEVAKELGIYELR---DKYPNEISGGQKQRT 160
Cdd:PRK11022 83 RRNLVGAEVAMIFQDpmTSLNPCYTVGFQIMEAIKVHQGgNKKTRRQRAIDLLNQVGIPDPAsrlDVYPHQLSGGMSQRV 162
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 161 SAGRAFIHDPSIIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHD-PVAASYCGRVIFIKDGQM 229
Cdd:PRK11022 163 MIAMAIACRPKLLIADEPTTALDVTIQAQIIELLLELQQKENMALVLITHDlALVAEAAHKIIVMYAGQV 232
|
|
| cbiO |
PRK13649 |
energy-coupling factor transporter ATPase; |
31-247 |
4.20e-22 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184208 [Multi-domain] Cd Length: 280 Bit Score: 92.50 E-value: 4.20e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 31 LKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAM-KEKQLAEFRKqHLGFIFQ--DYNLLDT 107
Cdd:PRK13649 23 LFDVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVRVDDTLITSTsKNKDIKQIRK-KVGLVFQfpESQLFEE 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 108 LTVKENILLPLSItKLSKKEANRKFEEVAKELGIYE-LRDKYPNEISGGQKQRTSAGRAFIHDPSIIFADEPTGALDSKS 186
Cdd:PRK13649 102 TVLKDVAFGPQNF-GVSQEEAEALAREKLALVGISEsLFEKNPFELSGGQMRRVAIAGILAMEPKILVLDEPTAGLDPKG 180
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
8G4D_C 187 ASDLLNKLSQLNQKrNATIIMVTH--DPVaASYCGRVIFIKDGqmytQLNKGGQDRQTfFQDI 247
Cdd:PRK13649 181 RKELMTLFKKLHQS-GMTIVLVTHlmDDV-ANYADFVYVLEKG----KLVLSGKPKDI-FQDV 236
|
|
| cbiO |
PRK13643 |
energy-coupling factor transporter ATPase; |
34-253 |
4.81e-22 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184203 [Multi-domain] Cd Length: 288 Bit Score: 92.49 E-value: 4.81e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 34 IDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAM-KEKQLAEFRKQhLGFIFQ--DYNLLDTLTV 110
Cdd:PRK13643 25 IDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKVTVGDIVVSSTsKQKEIKPVRKK-VGVVFQfpESQLFEETVL 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 111 KENILLPLSItKLSKKEANRKFEEVAKELGIY-ELRDKYPNEISGGQKQRTSAGRAFIHDPSIIFADEPTGALDSKSASD 189
Cdd:PRK13643 104 KDVAFGPQNF-GIPKEKAEKIAAEKLEMVGLAdEFWEKSPFELSGGQMRRVAIAGILAMEPEVLVLDEPTAGLDPKARIE 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 190 LLNKLSQLNQKrNATIIMVTH--DPVaASYCGRVIFIKDGQM--------------YTQLNKGGQDRQTFFQDIMKTQGV 253
Cdd:PRK13643 183 MMQLFESIHQS-GQTVVLVTHlmDDV-ADYADYVYLLEKGHIiscgtpsdvfqevdFLKAHELGVPKATHFADQLQKTGA 260
|
|
| cbiO |
PRK13640 |
energy-coupling factor transporter ATPase; |
20-232 |
7.34e-22 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184200 [Multi-domain] Cd Length: 282 Bit Score: 91.79 E-value: 7.34e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 20 SYGNKLNKQEVLKGIDIHIEKGEFVSIMGASGSGKTT---LLNVLSSIDQVSHGTIHINGNDMTamkEKQLAEFRKQhLG 96
Cdd:PRK13640 12 SFTYPDSKKPALNDISFSIPRGSWTALIGHNGSGKSTiskLINGLLLPDDNPNSKITVDGITLT---AKTVWDIREK-VG 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 97 FIFQDY-NLLDTLTVKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPSIIFA 175
Cdd:PRK13640 88 IVFQNPdNQFVGATVGDDVAFGLENRAVPRPEMIKIVRDVLADVGMLDYIDSEPANLSGGQKQRVAIAGILAVEPKIIIL 167
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
8G4D_C 176 DEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHDPVAASYCGRVIFIKDGQMYTQ 232
Cdd:PRK13640 168 DESTSMLDPAGKEQILKLIRKLKKKNNLTVISITHDIDEANMADQVLVLDDGKLLAQ 224
|
|
| PRK11160 |
PRK11160 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
12-232 |
9.66e-22 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236865 [Multi-domain] Cd Length: 574 Bit Score: 93.74 E-value: 9.66e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 12 LEANKIRKSYGNklNKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLaefr 91
Cdd:PRK11160 339 LTLNNVSFTYPD--QPQPVLKGLSLQIKAGEKVALLGRTGCGKSTLLQLLTRAWDPQQGEILLNGQPIADYSEAAL---- 412
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 92 KQHLGFIFQDYNLLDTlTVKENILlplsitkLSKKEAN-RKFEEVAKELGIYELRDKYP----------NEISGGQKQRT 160
Cdd:PRK11160 413 RQAISVVSQRVHLFSA-TLRDNLL-------LAAPNASdEALIEVLQQVGLEKLLEDDKglnawlgeggRQLSGGEQRRL 484
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
8G4D_C 161 SAGRAFIHDPSIIFADEPTGALDSKSASDLLNKLSQLNQkrNATIIMVTHDPVAASYCGRVIFIKDGQMYTQ 232
Cdd:PRK11160 485 GIARALLHDAPLLLLDEPTEGLDAETERQILELLAEHAQ--NKTVLMITHRLTGLEQFDRICVMDNGQIIEQ 554
|
|
| cbiO |
PRK13646 |
energy-coupling factor transporter ATPase; |
29-234 |
1.01e-21 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184205 [Multi-domain] Cd Length: 286 Bit Score: 91.38 E-value: 1.01e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 29 EVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTA-MKEKQLAEFRKQhLGFIFQ--DYNLL 105
Cdd:PRK13646 21 QAIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDITITHkTKDKYIRPVRKR-IGMVFQfpESQLF 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 106 DTLTVKENILLPLSItKLSKKEANRKFEEVAKELGI-YELRDKYPNEISGGQKQRTSAGRAFIHDPSIIFADEPTGALDS 184
Cdd:PRK13646 100 EDTVEREIIFGPKNF-KMNLDEVKNYAHRLLMDLGFsRDVMSQSPFQMSGGQMRKIAIVSILAMNPDIIVLDEPTAGLDP 178
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
8G4D_C 185 KSASDLLNKLSQLNQKRNATIIMVTHD-PVAASYCGRVIFIKDGQMYTQLN 234
Cdd:PRK13646 179 QSKRQVMRLLKSLQTDENKTIILVSHDmNEVARYADEVIVMKEGSIVSQTS 229
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
34-230 |
3.03e-21 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 92.77 E-value: 3.03e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 34 IDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMtamkEKQLAEFRkQHLGFIFQDYNLLDTLTVKEN 113
Cdd:TIGR01257 949 LNITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGKDI----ETNLDAVR-QSLGMCPQHNILFHHLTVAEH 1023
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 114 ILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPSIIFADEPTGALDSKSASDLLNK 193
Cdd:TIGR01257 1024 ILFYAQLKGRSWEEAQLEMEAMLEDTGLHHKRNEEAQDLSGGMQRKLSVAIAFVGDAKVVVLDEPTSGVDPYSRRSIWDL 1103
|
170 180 190
....*....|....*....|....*....|....*...
8G4D_C 194 LsqLNQKRNATIIMVTHDPVAASYCG-RVIFIKDGQMY 230
Cdd:TIGR01257 1104 L--LKYRSGRTIIMSTHHMDEADLLGdRIAIISQGRLY 1139
|
|
| PRK14239 |
PRK14239 |
phosphate transporter ATP-binding protein; Provisional |
26-229 |
5.03e-21 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184585 [Multi-domain] Cd Length: 252 Bit Score: 89.06 E-value: 5.03e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 26 NKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVS-----HGTIHINGNDMTAMKEKQLaEFRKQhLGFIFQ 100
Cdd:PRK14239 16 NKKKALNSVSLDFYPNEITALIGPSGSGKSTLLRSINRMNDLNpevtiTGSIVYNGHNIYSPRTDTV-DLRKE-IGMVFQ 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 101 DYNLLdTLTVKENILLPLSITKLSKKEA-NRKFEEVAKELGIY-ELRDKYPNE---ISGGQKQRTSAGRAFIHDPSIIFA 175
Cdd:PRK14239 94 QPNPF-PMSIYENVVYGLRLKGIKDKQVlDEAVEKSLKGASIWdEVKDRLHDSalgLSGGQQQRVCIARVLATSPKIILL 172
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
8G4D_C 176 DEPTGALDSKSASDLLNKLsqLNQKRNATIIMVTHDPVAASYCG-RVIFIKDGQM 229
Cdd:PRK14239 173 DEPTSALDPISAGKIEETL--LGLKDDYTMLLVTRSMQQASRISdRTGFFLDGDL 225
|
|
| cbiO |
PRK13641 |
energy-coupling factor transporter ATPase; |
31-229 |
5.51e-21 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237456 [Multi-domain] Cd Length: 287 Bit Score: 89.50 E-value: 5.51e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 31 LKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTA-MKEKQLAEFRKQ-HLGFIFQDYNLLDTL 108
Cdd:PRK13641 23 LDNISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIAGYHITPeTGNKNLKKLRKKvSLVFQFPEAQLFENT 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 109 TVKENILLPLSItKLSKKEANRKFEEVAKELGIYE-LRDKYPNEISGGQKQRTSAGRAFIHDPSIIFADEPTGALDSKSA 187
Cdd:PRK13641 103 VLKDVEFGPKNF-GFSEDEAKEKALKWLKKVGLSEdLISKSPFELSGGQMRRVAIAGVMAYEPEILCLDEPAAGLDPEGR 181
|
170 180 190 200
....*....|....*....|....*....|....*....|....
8G4D_C 188 SDLLnKLSQLNQKRNATIIMVTH--DPVaASYCGRVIFIKDGQM 229
Cdd:PRK13641 182 KEMM-QLFKDYQKAGHTVILVTHnmDDV-AEYADDVLVLEHGKL 223
|
|
| GldA_ABC_ATP |
TIGR03522 |
gliding motility-associated ABC transporter ATP-binding subunit GldA; Members of this protein ... |
12-229 |
5.51e-21 |
|
gliding motility-associated ABC transporter ATP-binding subunit GldA; Members of this protein family are exclusive to the Bacteroidetes phylum (previously Cytophaga-Flavobacteria-Bacteroides). GldA is an ABC transporter ATP-binding protein (pfam00005) linked to a type of rapid surface gliding motility found in certain Bacteroidetes, such as Flavobacterium johnsoniae and Cytophaga hutchinsonii. Knockouts of GldA abolish the gliding phenotype. Gliding motility appears closely linked to chitin utilization in the model species Flavobacterium johnsoniae. Bacteroidetes with members of this protein family appear to have all of the genes associated with gliding motility.
Pssm-ID: 132561 [Multi-domain] Cd Length: 301 Bit Score: 89.83 E-value: 5.51e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 12 LEANKIRKSYGnklnKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGND-MTAMKEKQlaef 90
Cdd:TIGR03522 3 IRVSSLTKLYG----TQNALDEVSFEAQKGRIVGFLGPNGAGKSTTMKIITGYLPPDSGSVQVCGEDvLQNPKEVQ---- 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 91 rkQHLGFIFQDYNLLDTLTVKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDP 170
Cdd:TIGR03522 75 --RNIGYLPEHNPLYLDMYVREYLQFIAGIYGMKGQLLKQRVEEMIELVGLRPEQHKKIGQLSKGYRQRVGLAQALIHDP 152
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
8G4D_C 171 SIIFADEPTGALDSKSASDLLNKLSQLNQKRnaTIIMVTH--DPVAAsYCGRVIFIKDGQM 229
Cdd:TIGR03522 153 KVLILDEPTTGLDPNQLVEIRNVIKNIGKDK--TIILSTHimQEVEA-ICDRVIIINKGKI 210
|
|
| PRK11831 |
PRK11831 |
phospholipid ABC transporter ATP-binding protein MlaF; |
34-211 |
9.13e-21 |
|
phospholipid ABC transporter ATP-binding protein MlaF;
Pssm-ID: 236997 [Multi-domain] Cd Length: 269 Bit Score: 88.67 E-value: 9.13e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 34 IDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLAEFRKQhLGFIFQDYNLLDTLTVKEN 113
Cdd:PRK11831 26 ISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHGEILFDGENIPAMSRSRLYTVRKR-MSMLFQSGALFTDMNVFDN 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 114 ILLPL-SITKLS----KKEANRKFEEVakelGIYELRDKYPNEISGGQKQRTSAGRAFIHDPSIIFADEPTGALDSKSAS 188
Cdd:PRK11831 105 VAYPLrEHTQLPapllHSTVMMKLEAV----GLRGAAKLMPSELSGGMARRAALARAIALEPDLIMFDEPFVGQDPITMG 180
|
170 180
....*....|....*....|...
8G4D_C 189 DLLNKLSQLNQKRNATIIMVTHD 211
Cdd:PRK11831 181 VLVKLISELNSALGVTCVVVSHD 203
|
|
| PRK10247 |
PRK10247 |
putative ABC transporter ATP-binding protein YbbL; Provisional |
11-222 |
1.07e-20 |
|
putative ABC transporter ATP-binding protein YbbL; Provisional
Pssm-ID: 182331 [Multi-domain] Cd Length: 225 Bit Score: 87.46 E-value: 1.07e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 11 ILEANKIrksyGNKLNKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQlaeF 90
Cdd:PRK10247 7 LLQLQNV----GYLAGDAKILNNISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTLLFEGEDISTLKPEI---Y 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 91 RKQhLGFIFQDYNLLDTlTVKENILLPLSITKlsKKEANRKFeevAKELGIYELRD----KYPNEISGGQKQRTSAGRAF 166
Cdd:PRK10247 80 RQQ-VSYCAQTPTLFGD-TVYDNLIFPWQIRN--QQPDPAIF---LDDLERFALPDtiltKNIAELSGGEKQRISLIRNL 152
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
8G4D_C 167 IHDPSIIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHDPVAASYCGRVI 222
Cdd:PRK10247 153 QFMPKVLLLDEITSALDESNKHNVNEIIHRYVREQNIAVLWVTHDKDEINHADKVI 208
|
|
| phnK |
PRK11701 |
phosphonate C-P lyase system protein PhnK; Provisional |
11-233 |
1.11e-20 |
|
phosphonate C-P lyase system protein PhnK; Provisional
Pssm-ID: 183280 [Multi-domain] Cd Length: 258 Bit Score: 88.06 E-value: 1.11e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 11 ILEANKIRKSYGNKLNKQEVlkGIDIHieKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLAEF 90
Cdd:PRK11701 6 LLSVRGLTKLYGPRKGCRDV--SFDLY--PGEVLGIVGESGSGKTTLLNALSARLAPDAGEVHYRMRDGQLRDLYALSEA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 91 RKQHL-----GFIFQdyNLLDTL----TVKENILLPL---------SItklsKKEANRKFEEVakELGIYELRDKyPNEI 152
Cdd:PRK11701 82 ERRRLlrtewGFVHQ--HPRDGLrmqvSAGGNIGERLmavgarhygDI----RATAGDWLERV--EIDAARIDDL-PTTF 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 153 SGGQKQRTSAGRAFIHDPSIIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHD-PVAASYCGRVIFIKDGQM-- 229
Cdd:PRK11701 153 SGGMQQRLQIARNLVTHPRLVFMDEPTGGLDVSVQARLLDLLRGLVRELGLAVVIVTHDlAVARLLAHRLLVMKQGRVve 232
|
250
....*....|....*...
8G4D_C 230 --------------YTQL 233
Cdd:PRK11701 233 sgltdqvlddpqhpYTQL 250
|
|
| PRK10261 |
PRK10261 |
glutathione transporter ATP-binding protein; Provisional |
41-224 |
1.46e-20 |
|
glutathione transporter ATP-binding protein; Provisional
Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 90.68 E-value: 1.46e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 41 GEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLAEFRKQhLGFIFQD-YNLLDT-LTVKENILLPL 118
Cdd:PRK10261 350 GETLSLVGESGSGKSTTGRALLRLVESQGGEIIFNGQRIDTLSPGKLQALRRD-IQFIFQDpYASLDPrQTVGDSIMEPL 428
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 119 SITKL-SKKEANRKFEEVAKELGIY-ELRDKYPNEISGGQKQRTSAGRAFIHDPSIIFADEPTGALDSKSASDLLNKLSQ 196
Cdd:PRK10261 429 RVHGLlPGKAAAARVAWLLERVGLLpEHAWRYPHEFSGGQRQRICIARALALNPKVIIADEAVSALDVSIRGQIINLLLD 508
|
170 180 190
....*....|....*....|....*....|....*..
8G4D_C 197 LNQKRNATIIMVTHD---------PVAASYCGRVIFI 224
Cdd:PRK10261 509 LQRDFGIAYLFISHDmavverishRVAVMYLGQIVEI 545
|
|
| bacteriocin_ABC |
TIGR01193 |
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The ... |
12-232 |
1.61e-20 |
|
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The amino terminal domain (pfam03412) processes the N-terminal leader peptide from the bacteriocin while C-terminal domains resemble ABC transporter membrane protein and ATP-binding cassette domain. In general, bacteriocins are agents which are responsible for killing or inhibiting the closely related species or even different strains of the same species. Bacteriocins are usually encoded by bacterial plasmids. Bacteriocins are named after the species and hence in literature one encounters various names e.g., leucocin from Leuconostic geldium; pedicocin from Pedicoccus acidilactici; sakacin from Lactobacillus sake etc. [Protein fate, Protein and peptide secretion and trafficking, Protein fate, Protein modification and repair, Transport and binding proteins, Other]
Pssm-ID: 130261 [Multi-domain] Cd Length: 708 Bit Score: 90.57 E-value: 1.61e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 12 LEANKIRKSYGNKlnkQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLaefr 91
Cdd:TIGR01193 474 IVINDVSYSYGYG---SNILSDISLTIKMNSKTTIVGMSGSGKSTLAKLLVGFFQARSGEILLNGFSLKDIDRHTL---- 546
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 92 KQHLGFIFQDYNLLDTlTVKENILLplsitklsKKEANRKFEEVAKELGIYELRDKYPN--------------EISGGQK 157
Cdd:TIGR01193 547 RQFINYLPQEPYIFSG-SILENLLL--------GAKENVSQDEIWAACEIAEIKDDIENmplgyqtelseegsSISGGQK 617
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
8G4D_C 158 QRTSAGRAFIHDPSIIFADEPTGALDSKSASDLLNKLSQLNQKrnaTIIMVTHDPVAASYCGRVIFIKDGQMYTQ 232
Cdd:TIGR01193 618 QRIALARALLTDSKVLILDESTSNLDTITEKKIVNNLLNLQDK---TIIFVAHRLSVAKQSDKIIVLDHGKIIEQ 689
|
|
| YhaQ |
COG4152 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
11-229 |
1.76e-20 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443322 [Multi-domain] Cd Length: 298 Bit Score: 88.24 E-value: 1.76e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 11 ILEANKIRKSYGNKLnkqeVLKGIDIHIEKGEFVSIMGASGSGKTTL----LNVLSSidqvSHGTIHINGNDMTAMKekq 86
Cdd:COG4152 1 MLELKGLTKRFGDKT----AVDDVSFTVPKGEIFGLLGPNGAGKTTTiriiLGILAP----DSGEVLWDGEPLDPED--- 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 87 laefrKQHLGFIFQDYNLLDTLTVKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAF 166
Cdd:COG4152 70 -----RRRIGYLPEERGLYPKMKVGEQLVYLARLKGLSKAEAKRRADEWLERLGLGDRANKKVEELSKGNQQKVQLIAAL 144
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
8G4D_C 167 IHDPSIIFADEPTGALDSKSASDLLNKLSQLNQKrNATIIMVTHD-PVAASYCGRVIFIKDGQM 229
Cdd:COG4152 145 LHDPELLILDEPFSGLDPVNVELLKDVIRELAAK-GTTVIFSSHQmELVEELCDRIVIINKGRK 207
|
|
| YddA |
COG4178 |
ABC-type uncharacterized transport system, permease and ATPase components [General function ... |
26-228 |
7.87e-20 |
|
ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];
Pssm-ID: 443337 [Multi-domain] Cd Length: 571 Bit Score: 88.33 E-value: 7.87e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 26 NKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINgndmtamkekqlaefRKQHLGFIFQD-YNL 104
Cdd:COG4178 374 DGRPLLEDLSLSLKPGERLLITGPSGSGKSTLLRAIAGLWPYGSGRIARP---------------AGARVLFLPQRpYLP 438
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 105 LDTLtvKENILLPLSITKLSKKEAnrkfEEVAKELGIYELRDKY------PNEISGGQKQRTSAGRAFIHDPSIIFADEP 178
Cdd:COG4178 439 LGTL--REALLYPATAEAFSDAEL----REALEAVGLGHLAERLdeeadwDQVLSLGEQQRLAFARLLLHKPDWLFLDEA 512
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
8G4D_C 179 TGALDSKSASDLLNKLSQlnQKRNATIIMVTHDPVAASYCGRVIFIKDGQ 228
Cdd:COG4178 513 TSALDEENEAALYQLLRE--ELPGTTVISVGHRSTLAAFHDRVLELTGDG 560
|
|
| cbiO |
PRK13645 |
energy-coupling factor transporter ATPase; |
31-222 |
8.08e-20 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184204 [Multi-domain] Cd Length: 289 Bit Score: 86.22 E-value: 8.08e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 31 LKGIDIHIEKGEFVSIMGASGSGKTTLLN-----VLSSIDQVSHGTIHINGNdmtAMKEKQLAEFRKQhLGFIFQ--DYN 103
Cdd:PRK13645 27 LNNTSLTFKKNKVTCVIGTTGSGKSTMIQltnglIISETGQTIVGDYAIPAN---LKKIKEVKRLRKE-IGLVFQfpEYQ 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 104 LLDTLTVKENILLPLSITKlSKKEANRKFEEVAKELGI-YELRDKYPNEISGGQKQRTSAGRAFIHDPSIIFADEPTGAL 182
Cdd:PRK13645 103 LFQETIEKDIAFGPVNLGE-NKQEAYKKVPELLKLVQLpEDYVKRSPFELSGGQKRRVALAGIIAMDGNTLVLDEPTGGL 181
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
8G4D_C 183 DSKSASDLLNKLSQLNQKRNATIIMVTH---------DPVAASYCGRVI 222
Cdd:PRK13645 182 DPKGEEDFINLFERLNKEYKKRIIMVTHnmdqvlriaDEVIVMHEGKVI 230
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
14-231 |
8.27e-20 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 88.20 E-value: 8.27e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 14 ANKIRKSYGNKlnkqEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNdmtamkekqlaefrkQ 93
Cdd:COG0488 1 LENLSKSFGGR----PLLDDVSLSINPGDRIGLVGRNGAGKSTLLKILAGELEPDSGEVSIPKG---------------L 61
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 94 HLGFIFQDYNLLDTLTVKENIL--------LPLSITKLSKK------------------------EANRKFEEVAKELGI 141
Cdd:COG0488 62 RIGYLPQEPPLDDDLTVLDTVLdgdaelraLEAELEELEAKlaepdedlerlaelqeefealggwEAEARAEEILSGLGF 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 142 Y-ELRDKYPNEISGGQKQRTSAGRAFIHDPSIIFADEPTGALDSKSasdlLNKLSQLNQKRNATIIMVTHD-----PVaa 215
Cdd:COG0488 142 PeEDLDRPVSELSGGWRRRVALARALLSEPDLLLLDEPTNHLDLES----IEWLEEFLKNYPGTVLVVSHDryfldRV-- 215
|
250
....*....|....*.
8G4D_C 216 syCGRVIFIKDGQMYT 231
Cdd:COG0488 216 --ATRILELDRGKLTL 229
|
|
| ABCC_MRP_domain2 |
cd03244 |
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ... |
26-228 |
2.11e-19 |
|
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213211 [Multi-domain] Cd Length: 221 Bit Score: 83.70 E-value: 2.11e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 26 NKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLaefrKQHLGFIFQDYNLL 105
Cdd:cd03244 15 NLPPVLKNISFSIKPGEKVGIVGRTGSGKSSLLLALFRLVELSSGSILIDGVDISKIGLHDL----RSRISIIPQDPVLF 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 106 DTlTVKENiLLPLSitKLSKKEANRKFEEVA-KELgIYELRDKYPNEI-------SGGQKQRTSAGRAFIHDPSIIFADE 177
Cdd:cd03244 91 SG-TIRSN-LDPFG--EYSDEELWQALERVGlKEF-VESLPGGLDTVVeeggenlSVGQRQLLCLARALLRKSKILVLDE 165
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
8G4D_C 178 PTGALDSKSASdLLNKLSQLNQKrNATIIMVTH--DPVAAsyCGRVIFIKDGQ 228
Cdd:cd03244 166 ATASVDPETDA-LIQKTIREAFK-DCTVLTIAHrlDTIID--SDRILVLDKGR 214
|
|
| ABC_Carb_Monos_II |
cd03215 |
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
30-229 |
2.42e-19 |
|
Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213182 [Multi-domain] Cd Length: 182 Bit Score: 82.48 E-value: 2.42e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 30 VLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAmkeKQLAEFRKQHLGFIFQD---YNLLD 106
Cdd:cd03215 15 AVRDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGEITLDGKPVTR---RSPRDAIRAGIAYVPEDrkrEGLVL 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 107 TLTVKENILLPLSitklskkeanrkfeevakelgiyelrdkypneISGGQKQRTSAGRAFIHDPSIIFADEPTGALDSKS 186
Cdd:cd03215 92 DLSVAENIALSSL--------------------------------LSGGNQQKVVLARWLARDPRVLILDEPTRGVDVGA 139
|
170 180 190 200
....*....|....*....|....*....|....*....|....
8G4D_C 187 ASDLLNKLSQLNQkRNATIIMVTHD-PVAASYCGRVIFIKDGQM 229
Cdd:cd03215 140 KAEIYRLIRELAD-AGKAVLLISSElDELLGLCDRILVMYEGRI 182
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
12-227 |
3.59e-19 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 86.38 E-value: 3.59e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 12 LEANKIRKSYGnklnKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLAEFr 91
Cdd:PRK09700 6 ISMAGIGKSFG----PVHALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNINYNKLDHKLAAQL- 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 92 kqHLGFIFQDYNLLDTLTVKENILLPLSITK-------LSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGR 164
Cdd:PRK09700 81 --GIGIIYQELSVIDELTVLENLYIGRHLTKkvcgvniIDWREMRVRAAMMLLRVGLKVDLDEKVANLSISHKQMLEIAK 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
8G4D_C 165 AFIHDPSIIFADEPTGALDSKSASDLLNKLSQLnQKRNATIIMVTHD-PVAASYCGRVIFIKDG 227
Cdd:PRK09700 159 TLMLDAKVIIMDEPTSSLTNKEVDYLFLIMNQL-RKEGTAIVYISHKlAEIRRICDRYTVMKDG 221
|
|
| livF |
PRK11614 |
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF; |
10-208 |
3.61e-19 |
|
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
Pssm-ID: 183231 [Multi-domain] Cd Length: 237 Bit Score: 83.39 E-value: 3.61e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 10 VILEANKIRKSYGnklnKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTamkEKQLAE 89
Cdd:PRK11614 4 VMLSFDKVSAHYG----KIQALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVFDGKDIT---DWQTAK 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 90 FRKQHLGFIFQDYNLLDTLTVKENilLPLSITKLSKKEANRKFEEVAKELG-IYELRDKYPNEISGGQKQRTSAGRAFIH 168
Cdd:PRK11614 77 IMREAVAIVPEGRRVFSRMTVEEN--LAMGGFFAERDQFQERIKWVYELFPrLHERRIQRAGTMSGGEQQMLAIGRALMS 154
|
170 180 190 200
....*....|....*....|....*....|....*....|
8G4D_C 169 DPSIIFADEPTGALDSKSASDLLNKLSQLNQKrNATIIMV 208
Cdd:PRK11614 155 QPRLLLLDEPSLGLAPIIIQQIFDTIEQLREQ-GMTIFLV 193
|
|
| PRK10895 |
PRK10895 |
lipopolysaccharide ABC transporter ATP-binding protein; Provisional |
11-190 |
4.00e-19 |
|
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
Pssm-ID: 182817 [Multi-domain] Cd Length: 241 Bit Score: 83.40 E-value: 4.00e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 11 ILEANKIRKSYGNKlnkqEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKekqLAEF 90
Cdd:PRK10895 3 TLTAKNLAKAYKGR----RVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDEDISLLP---LHAR 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 91 RKQHLGFIFQDYNLLDTLTVKENILLPLSITK-LSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHD 169
Cdd:PRK10895 76 ARRGIGYLPQEASIFRRLSVYDNLMAVLQIRDdLSAEQREDRANELMEEFHIEHLRDSMGQSLSGGERRRVEIARALAAN 155
|
170 180
....*....|....*....|.
8G4D_C 170 PSIIFADEPTGALDSKSASDL 190
Cdd:PRK10895 156 PKFILLDEPFAGVDPISVIDI 176
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
11-228 |
4.39e-19 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 86.03 E-value: 4.39e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 11 ILEANKIRKSYGNklnkQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIdqVSHGT----IHINGNDMTAmkeKQ 86
Cdd:TIGR02633 1 LLEMKGIVKTFGG----VKALDGIDLEVRPGECVGLCGENGAGKSTLMKILSGV--YPHGTwdgeIYWSGSPLKA---SN 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 87 LAEFRKQHLGFIFQDYNLLDTLTVKENILLPLSIT----KLSKKEANRKFEEVAKELGIYELRDKYP-NEISGGQKQRTS 161
Cdd:TIGR02633 72 IRDTERAGIVIIHQELTLVPELSVAENIFLGNEITlpggRMAYNAMYLRAKNLLRELQLDADNVTRPvGDYGGGQQQLVE 151
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
8G4D_C 162 AGRAFIHDPSIIFADEPTGALDSKSASDLLNKLSQLnQKRNATIIMVTH--DPVAAsYCGRVIFIKDGQ 228
Cdd:TIGR02633 152 IAKALNKQARLLILDEPSSSLTEKETEILLDIIRDL-KAHGVACVYISHklNEVKA-VCDTICVIRDGQ 218
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
24-229 |
5.14e-19 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 86.01 E-value: 5.14e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 24 KLNKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQ--------------------------------VSHGT 71
Cdd:TIGR03269 9 KFDGKEVLKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGMDQyeptsgriiyhvalcekcgyverpskvgepcpVCGGT 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 72 IHINGNDMTAMKEKQLAEFRKQhLGFIFQ-DYNLLDTLTVKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPN 150
Cdd:TIGR03269 89 LEPEEVDFWNLSDKLRRRIRKR-IAIMLQrTFALYGDDTVLDNVLEALEEIGYEGKEAVGRAVDLIEMVQLSHRITHIAR 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 151 EISGGQKQRTSAGRAFIHDPSIIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHDP-VAASYCGRVIFIKDGQM 229
Cdd:TIGR03269 168 DLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEAVKASGISMVLTSHWPeVIEDLSDKAIWLENGEI 247
|
|
| PRK13657 |
PRK13657 |
glucan ABC transporter ATP-binding protein/ permease; |
20-222 |
8.60e-19 |
|
glucan ABC transporter ATP-binding protein/ permease;
Pssm-ID: 184214 [Multi-domain] Cd Length: 588 Bit Score: 85.40 E-value: 8.60e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 20 SYGNKlnKQEVlKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLaefrKQHLGFIF 99
Cdd:PRK13657 343 SYDNS--RQGV-EDVSFEAKPGQTVAIVGPTGAGKSTLINLLQRVFDPQSGRILIDGTDIRTVTRASL----RRNIAVVF 415
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 100 QDYNLLDTlTVKENIllplSITKLSKKEAN-RKFEEVAKELGIYELR-DKYP-------NEISGGQKQRTSAGRAFIHDP 170
Cdd:PRK13657 416 QDAGLFNR-SIEDNI----RVGRPDATDEEmRAAAERAQAHDFIERKpDGYDtvvgergRQLSGGERQRLAIARALLKDP 490
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
8G4D_C 171 SIIFADEPTGALDS------KSASDLLNK-------LSQLNQKRNATIIMVTHDpvaasycGRVI 222
Cdd:PRK13657 491 PILILDEATSALDVeteakvKAALDELMKgrttfiiAHRLSTVRNADRILVFDN-------GRVV 548
|
|
| SapD |
COG4170 |
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms]; |
30-219 |
1.18e-18 |
|
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];
Pssm-ID: 443330 [Multi-domain] Cd Length: 331 Bit Score: 83.80 E-value: 1.18e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 30 VLKGIDIHIEKGEFVSIMGASGSGKT----TLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLAEFRKQHLGFIFQDYN-L 104
Cdd:COG4170 22 AVDRVSLTLNEGEIRGLVGESGSGKSliakAICGITKDNWHVTADRFRWNGIDLLKLSPRERRKIIGREIAMIFQEPSsC 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 105 LD-TLTVKENILLPLSITKLSKKEANRKFE--EVAKEL----GIYELRD---KYPNEISGGQKQRTSAGRAFIHDPSIIF 174
Cdd:COG4170 102 LDpSAKIGDQLIEAIPSWTFKGKWWQRFKWrkKRAIELlhrvGIKDHKDimnSYPHELTEGECQKVMIAMAIANQPRLLI 181
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
8G4D_C 175 ADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHDPVAAS---------YCG 219
Cdd:COG4170 182 ADEPTNAMESTTQAQIFRLLARLNQLQGTSILLISHDLESISqwadtitvlYCG 235
|
|
| cbiO |
PRK13652 |
cobalt transporter ATP-binding subunit; Provisional |
29-211 |
1.32e-18 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 172200 [Multi-domain] Cd Length: 277 Bit Score: 82.93 E-value: 1.32e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 29 EVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTamkEKQLAEFRKqHLGFIFQ--DYNLLD 106
Cdd:PRK13652 18 EALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSVLIRGEPIT---KENIREVRK-FVGLVFQnpDDQIFS 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 107 TlTVKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPSIIFADEPTGALDSKS 186
Cdd:PRK13652 94 P-TVEQDIAFGPINLGLDEETVAHRVSSALHMLGLEELRDRVPHHLSGGEKKRVAIAGVIAMEPQVLVLDEPTAGLDPQG 172
|
170 180
....*....|....*....|....*
8G4D_C 187 ASDLLNKLSQLNQKRNATIIMVTHD 211
Cdd:PRK13652 173 VKELIDFLNDLPETYGMTVIFSTHQ 197
|
|
| 3a01208 |
TIGR00958 |
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other] |
20-254 |
1.51e-18 |
|
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273363 [Multi-domain] Cd Length: 711 Bit Score: 84.77 E-value: 1.51e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 20 SYGNKLNKQeVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLaefrKQHLGFIF 99
Cdd:TIGR00958 487 SYPNRPDVP-VLKGLTFTLHPGEVVALVGPSGSGKSTVAALLQNLYQPTGGQVLLDGVPLVQYDHHYL----HRQVALVG 561
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 100 QDyNLLDTLTVKENILLPLSITKLSKKEAnrkfeeVAKELG----IYELRDKYPNEI-------SGGQKQRTSAGRAFIH 168
Cdd:TIGR00958 562 QE-PVLFSGSVRENIAYGLTDTPDEEIMA------AAKAANahdfIMEFPNGYDTEVgekgsqlSGGQKQRIAIARALVR 634
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 169 DPSIIFADEPTGALDSKSASdllnKLSQLNQKRNATIIMVTHDPVAASYCGRVIFIKDGQMYTQLNkggqdrqtfFQDIM 248
Cdd:TIGR00958 635 KPRVLILDEATSALDAECEQ----LLQESRSRASRTVLLIAHRLSTVERADQILVLKKGSVVEMGT---------HKQLM 701
|
....*.
8G4D_C 249 KTQGVL 254
Cdd:TIGR00958 702 EDQGCY 707
|
|
| PRK11174 |
PRK11174 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
34-210 |
2.51e-18 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236870 [Multi-domain] Cd Length: 588 Bit Score: 84.13 E-value: 2.51e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 34 IDIHIEKGEFVSIMGASGSGKTTLLNVLSSIdqVSH-GTIHINGndmTAMKEKQLAEFRkQHLGFIFQDYNLLDTlTVKE 112
Cdd:PRK11174 369 LNFTLPAGQRIALVGPSGAGKTSLLNALLGF--LPYqGSLKING---IELRELDPESWR-KHLSWVGQNPQLPHG-TLRD 441
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 113 NILLplsitklSKKEAN-RKFEEVAKELGIYELRDKYPN-----------EISGGQKQRTSAGRAFIHDPSIIFADEPTG 180
Cdd:PRK11174 442 NVLL-------GNPDASdEQLQQALENAWVSEFLPLLPQgldtpigdqaaGLSVGQAQRLALARALLQPCQLLLLDEPTA 514
|
170 180 190
....*....|....*....|....*....|
8G4D_C 181 ALDSKSASDLLNKLSQLNQKRnaTIIMVTH 210
Cdd:PRK11174 515 SLDAHSEQLVMQALNAASRRQ--TTLMVTH 542
|
|
| SufC |
COG0396 |
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ... |
26-210 |
3.31e-18 |
|
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440165 [Multi-domain] Cd Length: 245 Bit Score: 80.88 E-value: 3.31e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 26 NKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSID--QVSHGTIHINGNDMTAMKekqlAEFR-KQHLGFIFQD- 101
Cdd:COG0396 11 EGKEILKGVNLTIKPGEVHAIMGPNGSGKSTLAKVLMGHPkyEVTSGSILLDGEDILELS----PDERaRAGIFLAFQYp 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 102 --------YNLLdtLTVKENILLPlsitKLSKKEANRKFEEVAKELGI-YELRDKYPNE-ISGGQKQRTSAGRAFIHDPS 171
Cdd:COG0396 87 veipgvsvSNFL--RTALNARRGE----ELSAREFLKLLKEKMKELGLdEDFLDRYVNEgFSGGEKKRNEILQMLLLEPK 160
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
8G4D_C 172 IIFADEPtgalDS-------KSASDLLNKLsqlnQKRNATIIMVTH 210
Cdd:COG0396 161 LAILDET----DSgldidalRIVAEGVNKL----RSPDRGILIITH 198
|
|
| cbiO |
PRK13631 |
cobalt transporter ATP-binding subunit; Provisional |
10-210 |
3.33e-18 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237451 [Multi-domain] Cd Length: 320 Bit Score: 82.21 E-value: 3.33e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 10 VILEANKIRKSYGNKLNKQ-EVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHI----NGNDMTAMKE 84
Cdd:PRK13631 20 IILRVKNLYCVFDEKQENElVALNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLIKSKYGTIQVgdiyIGDKKNNHEL 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 85 ------KQLAEFRK--QHLGFIFQ--DYNLLDTlTVKENILLPLSITKLSKKEANRKFEEVAKELGI-YELRDKYPNEIS 153
Cdd:PRK13631 100 itnpysKKIKNFKElrRRVSMVFQfpEYQLFKD-TIEKDIMFGPVALGVKKSEAKKLAKFYLNKMGLdDSYLERSPFGLS 178
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
8G4D_C 154 GGQKQRTSAGRAFIHDPSIIFADEPTGALDSKSASDLLnKLSQLNQKRNATIIMVTH 210
Cdd:PRK13631 179 GGQKRRVAIAGILAIQPEILIFDEPTAGLDPKGEHEMM-QLILDAKANNKTVFVITH 234
|
|
| PRK15112 |
PRK15112 |
peptide ABC transporter ATP-binding protein SapF; |
29-209 |
4.91e-18 |
|
peptide ABC transporter ATP-binding protein SapF;
Pssm-ID: 185067 [Multi-domain] Cd Length: 267 Bit Score: 80.99 E-value: 4.91e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 29 EVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKqlaeFRKQHLGFIFQD-YNLLDT 107
Cdd:PRK15112 27 EAVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELLIDDHPLHFGDYS----YRSQRIRMIFQDpSTSLNP 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 108 LTVKENIL-LPLSI-TKLSKKEANRKFEEVAKELGIyeLRDK---YPNEISGGQKQRTSAGRAFIHDPSIIFADEPTGAL 182
Cdd:PRK15112 103 RQRISQILdFPLRLnTDLEPEQREKQIIETLRQVGL--LPDHasyYPHMLAPGQKQRLGLARALILRPKVIIADEALASL 180
|
170 180
....*....|....*....|....*..
8G4D_C 183 DSKSASDLLNKLSQLNQKRNATIIMVT 209
Cdd:PRK15112 181 DMSMRSQLINLMLELQEKQGISYIYVT 207
|
|
| ABCG_PDR_domain2 |
cd03232 |
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ... |
24-238 |
6.07e-18 |
|
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213199 [Multi-domain] Cd Length: 192 Bit Score: 79.21 E-value: 6.07e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 24 KLNKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSS--IDQVSHGTIHINGndmtamkEKQLAEFRKQhLGFIFQD 101
Cdd:cd03232 16 KGGKRQLLNNISGYVKPGTLTALMGESGAGKTTLLDVLAGrkTAGVITGEILING-------RPLDKNFQRS-TGYVEQQ 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 102 YNLLDTLTVKENILLplsitklskkEANrkfeevakelgiyeLRDkypneISGGQKQRTSAGRAFIHDPSIIFADEPTGA 181
Cdd:cd03232 88 DVHSPNLTVREALRF----------SAL--------------LRG-----LSVEQRKRLTIGVELAAKPSILFLDEPTSG 138
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 182 LDSKSAS---DLLNKLSQLNQkrnaTIIMVTHDPVAasycgrVIFIKDGQMYTqLNKGGQ 238
Cdd:cd03232 139 LDSQAAYnivRFLKKLADSGQ----AILCTIHQPSA------SIFEKFDRLLL-LKRGGK 187
|
|
| cbiO |
PRK13644 |
energy-coupling factor transporter ATPase; |
31-229 |
6.40e-18 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 106587 [Multi-domain] Cd Length: 274 Bit Score: 80.80 E-value: 6.40e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 31 LKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDmtAMKEKQLAEFRKQhLGFIFQD-YNLLDTLT 109
Cdd:PRK13644 18 LENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLVSGID--TGDFSKLQGIRKL-VGIVFQNpETQFVGRT 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 110 VKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPSIIFADEPTGALDSKSASD 189
Cdd:PRK13644 95 VEEDLAFGPENLCLPPIEIRKRVDRALAEIGLEKYRHRSPKTLSGGQGQCVALAGILTMEPECLIFDEVTSMLDPDSGIA 174
|
170 180 190 200
....*....|....*....|....*....|....*....|
8G4D_C 190 LLNKLSQLNQKrNATIIMVTHDPVAASYCGRVIFIKDGQM 229
Cdd:PRK13644 175 VLERIKKLHEK-GKTIVYITHNLEELHDADRIIVMDRGKI 213
|
|
| PRK13536 |
PRK13536 |
nodulation factor ABC transporter ATP-binding protein NodI; |
10-210 |
1.10e-17 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237419 [Multi-domain] Cd Length: 340 Bit Score: 81.03 E-value: 1.10e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 10 VILEANKIRKSYGNKLnkqeVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAmkEKQLAE 89
Cdd:PRK13536 40 VAIDLAGVSKSYGDKA----VVNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKITVLGVPVPA--RARLAR 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 90 FRkqhLGFIFQDYNLLDTLTVKENILLPLSITKLSkkeaNRKFEEVAKELGIYELRDKYPN----EISGGQKQRTSAGRA 165
Cdd:PRK13536 114 AR---IGVVPQFDNLDLEFTVRENLLVFGRYFGMS----TREIEAVIPSLLEFARLESKADarvsDLSGGMKRRLTLARA 186
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
8G4D_C 166 FIHDPSIIFADEPTGALDSKSASDLLNKLSQLnQKRNATIIMVTH 210
Cdd:PRK13536 187 LINDPQLLILDEPTTGLDPHARHLIWERLRSL-LARGKTILLTTH 230
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
12-228 |
1.57e-17 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 81.50 E-value: 1.57e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 12 LEANKIRKSY-GNKlnkqeVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNdmtAMKEKQLAEF 90
Cdd:PRK11288 5 LSFDGIGKTFpGVK-----ALDDISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGSILIDGQ---EMRFASTTAA 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 91 RKQHLGFIFQDYNLLDTLTVKENILL---PLSITKLSKKEANRKFEEVAKELGIyelrDKYPN----EISGGQKQRTSAG 163
Cdd:PRK11288 77 LAAGVAIIYQELHLVPEMTVAENLYLgqlPHKGGIVNRRLLNYEAREQLEHLGV----DIDPDtplkYLSIGQRQMVEIA 152
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
8G4D_C 164 RAFIHDPSIIFADEPTGALDSKSASDLLNKLSQLnQKRNATIIMVTH--DPVAAsYCGRVIFIKDGQ 228
Cdd:PRK11288 153 KALARNARVIAFDEPTSSLSAREIEQLFRVIREL-RAEGRVILYVSHrmEEIFA-LCDAITVFKDGR 217
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
28-211 |
3.29e-17 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 80.52 E-value: 3.29e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 28 QEVLKGIDIHIEKGEFVSIMGASGSGKT-TLLNVL----SSIDQVSHGTIHINGNDMTAMKEKQLAEFRKQHLGFIFQD- 101
Cdd:PRK15134 22 RTVVNDVSLQIEAGETLALVGESGSGKSvTALSILrllpSPPVVYPSGDIRFHGESLLHASEQTLRGVRGNKIAMIFQEp 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 102 ---YNLLDTLtvKENILLPLSITKLSKKEANRK-----FEEVAKELGIYELRDkYPNEISGGQKQRTSAGRAFIHDPSII 173
Cdd:PRK15134 102 mvsLNPLHTL--EKQLYEVLSLHRGMRREAARGeilncLDRVGIRQAAKRLTD-YPHQLSGGERQRVMIAMALLTRPELL 178
|
170 180 190
....*....|....*....|....*....|....*...
8G4D_C 174 FADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHD 211
Cdd:PRK15134 179 IADEPTTALDVSVQAQILQLLRELQQELNMGLLFITHN 216
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
11-227 |
3.56e-17 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 80.48 E-value: 3.56e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 11 ILEANKIRKSYGNklnkQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTamkekQLAEF 90
Cdd:PRK15439 11 LLCARSISKQYSG----VEVLKGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGTLEIGGNPCA-----RLTPA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 91 RKQHLG--FIFQDYNLLDTLTVKENILLPLSitklSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIH 168
Cdd:PRK15439 82 KAHQLGiyLVPQEPLLFPNLSVKENILFGLP----KRQASMQKMKQLLAALGCQLDLDSSAGSLEVADRQIVEILRGLMR 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 169 DPSIIFADEPTGALDSKSASDLLNKLSQLnQKRNATIIMVTHD-PVAASYCGRVIFIKDG 227
Cdd:PRK15439 158 DSRILILDEPTASLTPAETERLFSRIREL-LAQGVGIVFISHKlPEIRQLADRISVMRDG 216
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
11-228 |
6.59e-17 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 79.59 E-value: 6.59e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 11 ILEANKIRKSYGNklnkQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIdqVSHGT----IHINGNDMTAmkeKQ 86
Cdd:PRK13549 5 LLEMKNITKTFGG----VKALDNVSLKVRAGEIVSLCGENGAGKSTLMKVLSGV--YPHGTyegeIIFEGEELQA---SN 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 87 LAEFRKQHLGFIFQDYNLLDTLTVKENILLPLSITK---LSKKEANRKFEEVAKELGIyelrDKYPN----EISGGQKQR 159
Cdd:PRK13549 76 IRDTERAGIAIIHQELALVKELSVLENIFLGNEITPggiMDYDAMYLRAQKLLAQLKL----DINPAtpvgNLGLGQQQL 151
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
8G4D_C 160 TSAGRAFIHDPSIIFADEPTGALDSKSASDLLNKLSQLnQKRNATIIMVTH--DPVAAsYCGRVIFIKDGQ 228
Cdd:PRK13549 152 VEIAKALNKQARLLILDEPTASLTESETAVLLDIIRDL-KAHGIACIYISHklNEVKA-ISDTICVIRDGR 220
|
|
| 3a01205 |
TIGR00956 |
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other] |
24-214 |
7.38e-17 |
|
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 80.15 E-value: 7.38e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 24 KLNKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSsiDQVSHGTihINGNDMTAMKEKQLAEFRKQhLGFIFQDYN 103
Cdd:TIGR00956 772 KKEKRVILNNVDGWVKPGTLTALMGASGAGKTTLLNVLA--ERVTTGV--ITGGDRLVNGRPLDSSFQRS-IGYVQQQDL 846
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 104 LLDTLTVKENIL------LPLSItklSKKEANRKFEEVAKELGIYELRDKYPNEISGG----QKQRTSAGRAFIHDP-SI 172
Cdd:TIGR00956 847 HLPTSTVRESLRfsaylrQPKSV---SKSEKMEYVEEVIKLLEMESYADAVVGVPGEGlnveQRKRLTIGVELVAKPkLL 923
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
8G4D_C 173 IFADEPTGALDSKSA---SDLLNKLSQLNQkrnaTIIMVTHDPVA 214
Cdd:TIGR00956 924 LFLDEPTSGLDSQTAwsiCKLMRKLADHGQ----AILCTIHQPSA 964
|
|
| galliderm_ABC |
TIGR03740 |
gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Model TIGR03731 ... |
12-249 |
1.07e-16 |
|
gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Model TIGR03731 represents the family of all lantibiotics related to gallidermin, including epidermin, mutatin, and nisin. This protein family describes the ATP-binding subunit of a gallidermin/epidermin class lantibiotic protection transporter. It is largely restricted to gallidermin-family lantibiotic biosynthesis and export cassettes, but also occurs in orphan transporter cassettes in species that lack candidate lantibiotic precursor and synthetase genes.
Pssm-ID: 163452 [Multi-domain] Cd Length: 223 Bit Score: 76.67 E-value: 1.07e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 12 LEANKIRKSYGnklnKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTamkEKQLaefr 91
Cdd:TIGR03740 1 LETKNLSKRFG----KQTAVNNISLTVPKNSVYGLLGPNGAGKSTLLKMITGILRPTSGEIIFDGHPWT---RKDL---- 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 92 kQHLGFIFQDYNLLDTLTVKENILLPLSITKLSKKEanrkFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPS 171
Cdd:TIGR03740 70 -HKIGSLIESPPLYENLTARENLKVHTTLLGLPDSR----IDEVLNIVDLTNTGKKKAKQFSLGMKQRLGIAIALLNHPK 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 172 IIFADEPTGALDSKSASDlLNKLSQLNQKRNATIIMVTHD----PVAASYCGrviFIKDGQM-YTQLNKGGQDRQTFFQD 246
Cdd:TIGR03740 145 LLILDEPTNGLDPIGIQE-LRELIRSFPEQGITVILSSHIlsevQQLADHIG---IISEGVLgYQGKINKSENLEKLFVE 220
|
...
8G4D_C 247 IMK 249
Cdd:TIGR03740 221 VVK 223
|
|
| ABCG_PDR_domain1 |
cd03233 |
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ... |
10-223 |
1.22e-16 |
|
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213200 [Multi-domain] Cd Length: 202 Bit Score: 75.76 E-value: 1.22e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 10 VILEANKIRKSYGNKLNKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSI----DQVShGTIHINGNDMtamkeK 85
Cdd:cd03233 2 STLSWRNISFTTGKGRSKIPILKDFSGVVKPGEMVLVLGRPGSGCSTLLKALANRtegnVSVE-GDIHYNGIPY-----K 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 86 QLAEFRKQHLGFIFQDYNLLDTLTVKENIllplsitklskkeanrkfEEVAKELGiyelrDKYPNEISGGQKQRTSAGRA 165
Cdd:cd03233 76 EFAEKYPGEIIYVSEEDVHFPTLTVRETL------------------DFALRCKG-----NEFVRGISGGERKRVSIAEA 132
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
8G4D_C 166 FIHDPSIIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTH----------DPVAASYCGRVIF 223
Cdd:cd03233 133 LVSRASVLCWDNSTRGLDSSTALEILKCIRTMADVLKTTTFVSLYqasdeiydlfDKVLVLYEGRQIY 200
|
|
| PRK10261 |
PRK10261 |
glutathione transporter ATP-binding protein; Provisional |
31-228 |
1.27e-16 |
|
glutathione transporter ATP-binding protein; Provisional
Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 79.13 E-value: 1.27e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 31 LKGIDIHIEKGEFVSIMGASGSGKT-TLLNVLSSIDQvSHGTIHINGN----------DMTAMKEKQLAEFRKQHLGFIF 99
Cdd:PRK10261 32 VRNLSFSLQRGETLAIVGESGSGKSvTALALMRLLEQ-AGGLVQCDKMllrrrsrqviELSEQSAAQMRHVRGADMAMIF 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 100 QD--YNLLDTLTVKENILLPLSITK-LSKKEANRKFEEVAKELGIYE---LRDKYPNEISGGQKQRTSAGRAFIHDPSII 173
Cdd:PRK10261 111 QEpmTSLNPVFTVGEQIAESIRLHQgASREEAMVEAKRMLDQVRIPEaqtILSRYPHQLSGGMRQRVMIAMALSCRPAVL 190
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
8G4D_C 174 FADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHD-PVAASYCGRVIFIKDGQ 228
Cdd:PRK10261 191 IADEPTTALDVTIQAQILQLIKVLQKEMSMGVIFITHDmGVVAEIADRVLVMYQGE 246
|
|
| PRK10575 |
PRK10575 |
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC; |
41-232 |
1.55e-16 |
|
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
Pssm-ID: 182561 [Multi-domain] Cd Length: 265 Bit Score: 76.75 E-value: 1.55e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 41 GEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLAefRKqhLGFIFQDYNLLDTLTVKENILL---P 117
Cdd:PRK10575 37 GKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFA--RK--VAYLPQQLPAAEGMTVRELVAIgryP 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 118 L--SITKLSKkEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPSIIFADEPTGALDSKSASDLLNKLS 195
Cdd:PRK10575 113 WhgALGRFGA-ADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLALVH 191
|
170 180 190
....*....|....*....|....*....|....*...
8G4D_C 196 QLNQKRNATIIMVTHD-PVAASYCGRVIFIKDGQMYTQ 232
Cdd:PRK10575 192 RLSQERGLTVIAVLHDiNMAARYCDYLVALRGGEMIAQ 229
|
|
| ccmA |
TIGR01189 |
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ... |
29-213 |
2.85e-16 |
|
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]
Pssm-ID: 273491 [Multi-domain] Cd Length: 198 Bit Score: 74.70 E-value: 2.85e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 29 EVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTamkekQLAEFRKQHLGFIFQDYNLLDTL 108
Cdd:TIGR01189 14 MLFEGLSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRPDSGEVRWNGTPLA-----EQRDEPHENILYLGHLPGLKPEL 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 109 TVKENillpLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPSIIFADEPTGALDsKSAS 188
Cdd:TIGR01189 89 SALEN----LHFWAAIHGGAQRTIEDALAAVGLTGFEDLPAAQLSAGQQRRLALARLWLSRRPLWILDEPTTALD-KAGV 163
|
170 180
....*....|....*....|....*
8G4D_C 189 DLLNKLSQLNQKRNATIIMVTHDPV 213
Cdd:TIGR01189 164 ALLAGLLRAHLARGGIVLLTTHQDL 188
|
|
| PRK11176 |
PRK11176 |
lipid A ABC transporter ATP-binding protein/permease MsbA; |
31-210 |
3.62e-16 |
|
lipid A ABC transporter ATP-binding protein/permease MsbA;
Pssm-ID: 183016 [Multi-domain] Cd Length: 582 Bit Score: 77.75 E-value: 3.62e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 31 LKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDmtaMKEKQLAEFRKQ--------HLgfiFQDy 102
Cdd:PRK11176 359 LRNINFKIPAGKTVALVGRSGSGKSTIANLLTRFYDIDEGEILLDGHD---LRDYTLASLRNQvalvsqnvHL---FND- 431
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 103 nlldtlTVKENILLPlSITKLSKKEanrkFEEVAKELGIYELRDKYPN-----------EISGGQKQRTSAGRAFIHDPS 171
Cdd:PRK11176 432 ------TIANNIAYA-RTEQYSREQ----IEEAARMAYAMDFINKMDNgldtvigengvLLSGGQRQRIAIARALLRDSP 500
|
170 180 190
....*....|....*....|....*....|....*....
8G4D_C 172 IIFADEPTGALDSKSASDLLNKLSQLnqKRNATIIMVTH 210
Cdd:PRK11176 501 ILILDEATSALDTESERAIQAALDEL--QKNRTSLVIAH 537
|
|
| livG |
PRK11300 |
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional |
33-211 |
4.70e-16 |
|
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
Pssm-ID: 183080 [Multi-domain] Cd Length: 255 Bit Score: 75.41 E-value: 4.70e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 33 GIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLAefRKqhlGFI--FQDYNLLDTLTV 110
Cdd:PRK11300 23 NVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTILLRGQHIEGLPGHQIA--RM---GVVrtFQHVRLFREMTV 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 111 KENILLPLS-------ITKLSKKEANRKFEEVAKE--------LGIYELRDKYPNEISGGQKQRTSAGRAFIHDPSIIFA 175
Cdd:PRK11300 98 IENLLVAQHqqlktglFSGLLKTPAFRRAESEALDraatwlerVGLLEHANRQAGNLAYGQQRRLEIARCMVTQPEILML 177
|
170 180 190
....*....|....*....|....*....|....*.
8G4D_C 176 DEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHD 211
Cdd:PRK11300 178 DEPAAGLNPKETKELDELIAELRNEHNVTVLLIEHD 213
|
|
| ABCD_peroxisomal_ALDP |
cd03223 |
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ... |
30-212 |
5.73e-16 |
|
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).
Pssm-ID: 213190 [Multi-domain] Cd Length: 166 Bit Score: 73.34 E-value: 5.73e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 30 VLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINgndmtamkekqlaefRKQHLGFIFQD-YnlLDTL 108
Cdd:cd03223 16 LLKDLSFEIKPGDRLLITGPSGTGKSSLFRALAGLWPWGSGRIGMP---------------EGEDLLFLPQRpY--LPLG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 109 TVKENILLPLSitklskkeanrkfeevaKELgiyelrdkypneiSGGQKQRTSAGRAFIHDPSIIFADEPTGALDSKSAS 188
Cdd:cd03223 79 TLREQLIYPWD-----------------DVL-------------SGGEQQRLAFARLLLHKPKFVFLDEATSALDEESED 128
|
170 180
....*....|....*....|....
8G4D_C 189 DLLNKLsqlnQKRNATIIMVTHDP 212
Cdd:cd03223 129 RLYQLL----KELGITVISVGHRP 148
|
|
| ABCC_TAP |
cd03248 |
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ... |
20-229 |
9.26e-16 |
|
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.
Pssm-ID: 213215 [Multi-domain] Cd Length: 226 Bit Score: 74.04 E-value: 9.26e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 20 SYGNKLNKQeVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLAEfrkqHLGFIF 99
Cdd:cd03248 20 AYPTRPDTL-VLQDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQVLLDGKPISQYEHKYLHS----KVSLVG 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 100 QDYNLLdTLTVKENILLPL------SITKLSKKEANRKF-EEVAKelGIYELRDKYPNEISGGQKQRTSAGRAFIHDPSI 172
Cdd:cd03248 95 QEPVLF-ARSLQDNIAYGLqscsfeCVKEAAQKAHAHSFiSELAS--GYDTEVGEKGSQLSGGQKQRVAIARALIRNPQV 171
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
8G4D_C 173 IFADEPTGALDSKSASDLLNKLSQLNQKRnaTIIMVTHDPVAASYCGRVIFIKDGQM 229
Cdd:cd03248 172 LILDEATSALDAESEQQVQQALYDWPERR--TVLVIAHRLSTVERADQILVLDGGRI 226
|
|
| btuD |
PRK09536 |
corrinoid ABC transporter ATPase; Reviewed |
28-227 |
1.75e-15 |
|
corrinoid ABC transporter ATPase; Reviewed
Pssm-ID: 236554 [Multi-domain] Cd Length: 402 Bit Score: 75.26 E-value: 1.75e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 28 QEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLAefrkQHLGFIFQDYNLLDT 107
Cdd:PRK09536 16 TTVLDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLVAGDDVEALSARAAS----RRVASVPQDTSLSFE 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 108 LTVKENILLPLS--ITKLSKK-EANRKFEEVAKE-LGIYELRDKYPNEISGGQKQRTSAGRAFIHDPSIIFADEPTGALD 183
Cdd:PRK09536 92 FDVRQVVEMGRTphRSRFDTWtETDRAAVERAMErTGVAQFADRPVTSLSGGERQRVLLARALAQATPVLLLDEPTASLD 171
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
8G4D_C 184 SKSASDLLNKLSQLNQKrNATIIMVTHD-PVAASYCGRVIFIKDG 227
Cdd:PRK09536 172 INHQVRTLELVRRLVDD-GKTAVAAIHDlDLAARYCDELVLLADG 215
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
25-229 |
3.30e-15 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 74.67 E-value: 3.30e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 25 LNKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMT------AMKEKqLA---EFRKQHl 95
Cdd:COG1129 262 LSVGGVVRDVSFSVRAGEILGIAGLVGAGRTELARALFGADPADSGEIRLDGKPVRirsprdAIRAG-IAyvpEDRKGE- 339
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 96 GfIFQDynlldtLTVKENILLPL--SITK---LSKKEANRKFEEVAKELGIyelrdKYPN------EISGGQKQRTSAGR 164
Cdd:COG1129 340 G-LVLD------LSIRENITLASldRLSRgglLDRRRERALAEEYIKRLRI-----KTPSpeqpvgNLSGGNQQKVVLAK 407
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
8G4D_C 165 AFIHDPSIIFADEPT-----GAldsKSA-SDLLNKLSqlnqKRNATIIMVTHD-PVAASYCGRVIFIKDGQM 229
Cdd:COG1129 408 WLATDPKVLILDEPTrgidvGA---KAEiYRLIRELA----AEGKAVIVISSElPELLGLSDRILVMREGRI 472
|
|
| nikD |
PRK10418 |
nickel transporter ATP-binding protein NikD; Provisional |
28-245 |
8.40e-15 |
|
nickel transporter ATP-binding protein NikD; Provisional
Pssm-ID: 236688 [Multi-domain] Cd Length: 254 Bit Score: 72.04 E-value: 8.40e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 28 QEVLKGIDIHIEKGEFVSIMGASGSGKT----TLLNVLSSIDQVSHGTIHINGndmtamKEKQLAEFRKQHLGFIFQD-- 101
Cdd:PRK10418 16 QPLVHGVSLTLQRGRVLALVGGSGSGKSltcaAALGILPAGVRQTAGRVLLDG------KPVAPCALRGRKIATIMQNpr 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 102 --YNLLDTLT--VKENILlplsitKLSKKEANRKFEEVAKELGIYELR---DKYPNEISGGQKQRTSAGRAFIHDPSIIF 174
Cdd:PRK10418 90 saFNPLHTMHthARETCL------ALGKPADDATLTAALEAVGLENAArvlKLYPFEMSGGMLQRMMIALALLCEAPFII 163
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
8G4D_C 175 ADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHD-PVAASYCGRVIFIKDGQMYTQlnkggQDRQTFFQ 245
Cdd:PRK10418 164 ADEPTTDLDVVAQARILDLLESIVQKRALGMLLVTHDmGVVARLADDVAVMSHGRIVEQ-----GDVETLFN 230
|
|
| ATM1 |
COG5265 |
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ... |
29-210 |
1.06e-14 |
|
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444078 [Multi-domain] Cd Length: 605 Bit Score: 73.32 E-value: 1.06e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 29 EVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLaefrKQHLGFIFQD---YNll 105
Cdd:COG5265 372 PILKGVSFEVPAGKTVAIVGPSGAGKSTLARLLFRFYDVTSGRILIDGQDIRDVTQASL----RAAIGIVPQDtvlFN-- 445
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 106 DTLtvKENILLplsitklSKKEANR-KFEEVAK--ELG--IYELRDKYPNEI-------SGGQKQRTSAGRAFIHDPSII 173
Cdd:COG5265 446 DTI--AYNIAY-------GRPDASEeEVEAAARaaQIHdfIESLPDGYDTRVgerglklSGGEKQRVAIARTLLKNPPIL 516
|
170 180 190
....*....|....*....|....*....|....*..
8G4D_C 174 FADEPTGALDSKSASDLLNKLSQLNQKRnaTIIMVTH 210
Cdd:COG5265 517 IFDEATSALDSRTERAIQAALREVARGR--TTLVIAH 551
|
|
| PRK14271 |
PRK14271 |
phosphate ABC transporter ATP-binding protein; Provisional |
28-229 |
1.08e-14 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172759 [Multi-domain] Cd Length: 276 Bit Score: 72.05 E-value: 1.08e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 28 QEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSI-DQVS----HGTIHINGNDMtaMKEKQLAEFRKQhLGFIFQDY 102
Cdd:PRK14271 34 KTVLDQVSMGFPARAVTSLMGPTGSGKTTFLRTLNRMnDKVSgyrySGDVLLGGRSI--FNYRDVLEFRRR-VGMLFQRP 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 103 NLLdTLTVKENILLPLSITKLSKKeanRKFEEVAK----ELGIYE-LRDKY---PNEISGGQKQRTSAGRAFIHDPSIIF 174
Cdd:PRK14271 111 NPF-PMSIMDNVLAGVRAHKLVPR---KEFRGVAQarltEVGLWDaVKDRLsdsPFRLSGGQQQLLCLARTLAVNPEVLL 186
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
8G4D_C 175 ADEPTGALDSKSASDLLNKLSQLNQKrnATIIMVTHD-PVAASYCGRVIFIKDGQM 229
Cdd:PRK14271 187 LDEPTSALDPTTTEKIEEFIRSLADR--LTVIIVTHNlAQAARISDRAALFFDGRL 240
|
|
| PRK10789 |
PRK10789 |
SmdA family multidrug ABC transporter permease/ATP-binding protein; |
26-210 |
1.09e-14 |
|
SmdA family multidrug ABC transporter permease/ATP-binding protein;
Pssm-ID: 182732 [Multi-domain] Cd Length: 569 Bit Score: 73.21 E-value: 1.09e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 26 NKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMkekQLAEFRKQ-----HLGFIFQ 100
Cdd:PRK10789 326 TDHPALENVNFTLKPGQMLGICGPTGSGKSTLLSLIQRHFDVSEGDIRFHDIPLTKL---QLDSWRSRlavvsQTPFLFS 402
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 101 DynlldtlTVKENIllplsitKLSKKEANR-KFEEVAKELGIYE----LRDKYPNEI-------SGGQKQRTSAGRAFIH 168
Cdd:PRK10789 403 D-------TVANNI-------ALGRPDATQqEIEHVARLASVHDdilrLPQGYDTEVgergvmlSGGQKQRISIARALLL 468
|
170 180 190 200
....*....|....*....|....*....|....*....|..
8G4D_C 169 DPSIIFADEPTGALDSKSASDLLNKLSQLNQKRnaTIIMVTH 210
Cdd:PRK10789 469 NAEILILDDALSAVDGRTEHQILHNLRQWGEGR--TVIISAH 508
|
|
| MK0520 |
COG2401 |
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ... |
13-212 |
1.87e-14 |
|
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];
Pssm-ID: 441957 [Multi-domain] Cd Length: 222 Bit Score: 70.37 E-value: 1.87e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 13 EANKIRKSYGNKLNKQE--VLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLssidqvshgtihingndMTAMKEKQLAEF 90
Cdd:COG2401 26 RVAIVLEAFGVELRVVEryVLRDLNLEIEPGEIVLIVGASGSGKSTLLRLL-----------------AGALKGTPVAGC 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 91 RKQHLGFIFQDYNLLDTLTVKENILLP---LSITKLSkkEAnrkfeevakelgiYELRDKYPnEISGGQKQRTSAGRAFI 167
Cdd:COG2401 89 VDVPDNQFGREASLIDAIGRKGDFKDAvelLNAVGLS--DA-------------VLWLRRFK-ELSTGQKFRFRLALLLA 152
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
8G4D_C 168 HDPSIIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHDP 212
Cdd:COG2401 153 ERPKLLVIDEFCSHLDRQTAKRVARNLQKLARRAGITLVVATHHY 197
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
29-211 |
3.52e-14 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 71.60 E-value: 3.52e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 29 EVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKekqLAEFRKQHLGFIFQD---YNLL 105
Cdd:COG3845 272 PALKDVSLEVRAGEILGIAGVAGNGQSELAEALAGLRPPASGSIRLDGEDITGLS---PRERRRLGVAYIPEDrlgRGLV 348
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 106 DTLTVKENILLPLSITK-------LSKKEANRKFEEVAKELGIyelrdKYPNE------ISGGQKQRTSAGRAFIHDPSI 172
Cdd:COG3845 349 PDMSVAENLILGRYRRPpfsrggfLDRKAIRAFAEELIEEFDV-----RTPGPdtparsLSGGNQQKVILARELSRDPKL 423
|
170 180 190
....*....|....*....|....*....|....*....
8G4D_C 173 IFADEPTGALDSKSASDLLNKLSQLnQKRNATIIMVTHD 211
Cdd:COG3845 424 LIAAQPTRGLDVGAIEFIHQRLLEL-RDAGAAVLLISED 461
|
|
| PRK14258 |
PRK14258 |
phosphate ABC transporter ATP-binding protein; Provisional |
26-211 |
4.57e-14 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184593 [Multi-domain] Cd Length: 261 Bit Score: 70.07 E-value: 4.57e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 26 NKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVsHGTIHING-----NDMTAMKEKQLAEFRKQhLGFIFQ 100
Cdd:PRK14258 18 DTQKILEGVSMEIYQSKVTAIIGPSGCGKSTFLKCLNRMNEL-ESEVRVEGrveffNQNIYERRVNLNRLRRQ-VSMVHP 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 101 DYNLLdTLTVKENILLPLSITKLSKK-EANRKFEEVAKELGIY-ELRDKYPN---EISGGQKQRTSAGRAFIHDPSIIFA 175
Cdd:PRK14258 96 KPNLF-PMSVYDNVAYGVKIVGWRPKlEIDDIVESALKDADLWdEIKHKIHKsalDLSGGQQQRLCIARALAVKPKVLLM 174
|
170 180 190
....*....|....*....|....*....|....*.
8G4D_C 176 DEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHD 211
Cdd:PRK14258 175 DEPCFGLDPIASMKVESLIQSLRLRSELTMVIVSHN 210
|
|
| PRK13539 |
PRK13539 |
cytochrome c biogenesis protein CcmA; Provisional |
29-222 |
7.67e-14 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 237421 [Multi-domain] Cd Length: 207 Bit Score: 68.36 E-value: 7.67e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 29 EVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTamkEKQLAEfRKQHLGFifQDYnLLDTL 108
Cdd:PRK13539 16 VLFSGLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLDGGDID---DPDVAE-ACHYLGH--RNA-MKPAL 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 109 TVKENILL--------PLSItklskkeanrkfEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPSIIFADEPTG 180
Cdd:PRK13539 89 TVAENLEFwaaflggeELDI------------AAALEAVGLAPLAHLPFGYLSAGQKRRVALARLLVSNRPIWILDEPTA 156
|
170 180 190 200
....*....|....*....|....*....|....*....|..
8G4D_C 181 ALDSkSASDLLNKLSQLNQKRNATIIMVTHDPVAAsYCGRVI 222
Cdd:PRK13539 157 ALDA-AAVALFAELIRAHLAQGGIVIAATHIPLGL-PGAREL 196
|
|
| ABCC_NFT1 |
cd03369 |
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ... |
29-229 |
1.39e-13 |
|
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213269 [Multi-domain] Cd Length: 207 Bit Score: 67.82 E-value: 1.39e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 29 EVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLaefrKQHLGFIFQDYNLLDTl 108
Cdd:cd03369 22 PVLKNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAEEGKIEIDGIDISTIPLEDL----RSSLTIIPQDPTLFSG- 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 109 TVKENIllplsitklsKKEANRKFEEVAKELGIYElrdkYPNEISGGQKQRTSAGRAFIHDPSIIFADEPTGALDskSAS 188
Cdd:cd03369 97 TIRSNL----------DPFDEYSDEEIYGALRVSE----GGLNLSQGQRQLLCLARALLKRPRVLVLDEATASID--YAT 160
|
170 180 190 200
....*....|....*....|....*....|....*....|.
8G4D_C 189 DLLNKLSQLNQKRNATIIMVTHDPVAASYCGRVIFIKDGQM 229
Cdd:cd03369 161 DALIQKTIREEFTNSTILTIAHRLRTIIDYDKILVMDAGEV 201
|
|
| PRK14243 |
PRK14243 |
phosphate transporter ATP-binding protein; Provisional |
10-216 |
2.39e-13 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184588 [Multi-domain] Cd Length: 264 Bit Score: 67.88 E-value: 2.39e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 10 VILEANKIRKSYGNKLnkqeVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQV-----SHGTIHINGNDMTAmKE 84
Cdd:PRK14243 9 TVLRTENLNVYYGSFL----AVKNVWLDIPKNQITAFIGPSGCGKSTILRCFNRLNDLipgfrVEGKVTFHGKNLYA-PD 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 85 KQLAEFRKQhLGFIFQDYNLLDTlTVKENILLPLSITKLsKKEANRKFEEVAKELGIY-ELRDKYPNE---ISGGQKQRT 160
Cdd:PRK14243 84 VDPVEVRRR-IGMVFQKPNPFPK-SIYDNIAYGARINGY-KGDMDELVERSLRQAALWdEVKDKLKQSglsLSGGQQQRL 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
8G4D_C 161 SAGRAFIHDPSIIFADEPTGALDSKSASDLLNKLSQLnqKRNATIIMVTHDPVAAS 216
Cdd:PRK14243 161 CIARAIAVQPEVILMDEPCSALDPISTLRIEELMHEL--KEQYTIIIVTHNMQQAA 214
|
|
| ABC_FeS_Assembly |
cd03217 |
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ... |
24-237 |
3.04e-13 |
|
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.
Pssm-ID: 213184 [Multi-domain] Cd Length: 200 Bit Score: 66.40 E-value: 3.04e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 24 KLNKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLS--SIDQVSHGTIHINGNDMTAMKEKQLAefrKQHLGFIFQD 101
Cdd:cd03217 9 SVGGKEILKGVNLTIKKGEVHALMGPNGSGKSTLAKTIMghPKYEVTEGEILFKGEDITDLPPEERA---RLGIFLAFQY 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 102 ynlldtltvkenillPLSITKLSkkeaNRKFeevakelgiyeLRdkYPNE-ISGGQKQRTSAGRAFIHDPSIIFADEPTG 180
Cdd:cd03217 86 ---------------PPEIPGVK----NADF-----------LR--YVNEgFSGGEKKRNEILQLLLLEPDLAILDEPDS 133
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
8G4D_C 181 ALDSKSASDLLNKLSQLNQKRNATIImVTH----------DPVAASYCGRVIFIKDGQMYTQLNKGG 237
Cdd:cd03217 134 GLDIDALRLVAEVINKLREEGKSVLI-ITHyqrlldyikpDRVHVLYDGRIVKSGDKELALEIEKKG 199
|
|
| ABCC_SUR1_N |
cd03290 |
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ... |
31-227 |
5.06e-13 |
|
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.
Pssm-ID: 213257 [Multi-domain] Cd Length: 218 Bit Score: 66.20 E-value: 5.06e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 31 LKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLAEFRKQHLGFIFQDYNLLDTlTV 110
Cdd:cd03290 17 LSNINIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVHWSNKNESEPSFEATRSRNRYSVAYAAQKPWLLNA-TV 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 111 KENILLPLSITKlskkeanRKFEEVAKELGIYELRDKYPN-----------EISGGQKQRTSAGRAFIHDPSIIFADEPT 179
Cdd:cd03290 96 EENITFGSPFNK-------QRYKAVTDACSLQPDIDLLPFgdqteigergiNLSGGQRQRICVARALYQNTNIVFLDDPF 168
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
8G4D_C 180 GALDSKSASDLLNK-LSQLNQKRNATIIMVTHDPVAASYCGRVIFIKDG 227
Cdd:cd03290 169 SALDIHLSDHLMQEgILKFLQDDKRTLVLVTHKLQYLPHADWIIAMKDG 217
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
11-211 |
9.01e-13 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 67.65 E-value: 9.01e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 11 ILEANKIRKSYGNKlnkQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGtihingndmtamkEKQLAEF 90
Cdd:TIGR03719 4 IYTMNRVSKVVPPK---KEILKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVDKDFNG-------------EARPQPG 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 91 RKqhLGFIFQDYNLLDTLTVKENILLPLSitklSKKEANRKFEEV--------------AKELGIYE------------- 143
Cdd:TIGR03719 68 IK--VGYLPQEPQLDPTKTVRENVEEGVA----EIKDALDRFNEIsakyaepdadfdklAAEQAELQeiidaadawdlds 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 144 --------LR----DKYPNEISGGQKQRTSAGRAFIHDPSIIFADEPTGALDSKSASDLLNKLsqlnQKRNATIIMVTHD 211
Cdd:TIGR03719 142 qleiamdaLRcppwDADVTKLSGGERRRVALCRLLLSKPDMLLLDEPTNHLDAESVAWLERHL----QEYPGTVVAVTHD 217
|
|
| PRK13540 |
PRK13540 |
cytochrome c biogenesis protein CcmA; Provisional |
28-210 |
9.23e-13 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184127 [Multi-domain] Cd Length: 200 Bit Score: 65.36 E-value: 9.23e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 28 QEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMtamkEKQLAEFRKQhLGFIFQDYNLLDT 107
Cdd:PRK13540 14 QPLLQQISFHLPAGGLLHLKGSNGAGKTTLLKLIAGLLNPEKGEILFERQSI----KKDLCTYQKQ-LCFVGHRSGINPY 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 108 LTVKENILLPLSITklskkEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPSIIFADEPTGALDSKSA 187
Cdd:PRK13540 89 LTLRENCLYDIHFS-----PGAVGITELCRLFSLEHLIDYPCGLLSSGQKRQVALLRLWMSKAKLWLLDEPLVALDELSL 163
|
170 180
....*....|....*....|...
8G4D_C 188 SDLLNKLsQLNQKRNATIIMVTH 210
Cdd:PRK13540 164 LTIITKI-QEHRAKGGAVLLTSH 185
|
|
| PRK13538 |
PRK13538 |
cytochrome c biogenesis heme-transporting ATPase CcmA; |
33-215 |
9.73e-13 |
|
cytochrome c biogenesis heme-transporting ATPase CcmA;
Pssm-ID: 184125 [Multi-domain] Cd Length: 204 Bit Score: 65.21 E-value: 9.73e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 33 GIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEkqlaEFRKQ-----HLGFIfqdynlLDT 107
Cdd:PRK13538 19 GLSFTLNAGELVQIEGPNGAGKTSLLRILAGLARPDAGEVLWQGEPIRRQRD----EYHQDllylgHQPGI------KTE 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 108 LTVKENILLPLSITKLSKKEAN---------RKFEEV-AKELgiyelrdkypneiSGGQKQRTSAGRAFIHDPSIIFADE 177
Cdd:PRK13538 89 LTALENLRFYQRLHGPGDDEALwealaqvglAGFEDVpVRQL-------------SAGQQRRVALARLWLTRAPLWILDE 155
|
170 180 190
....*....|....*....|....*....|....*...
8G4D_C 178 PTGALDSKSASDLLNKLSQlNQKRNATIIMVTHDPVAA 215
Cdd:PRK13538 156 PFTAIDKQGVARLEALLAQ-HAEQGGMVILTTHQDLPV 192
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
10-228 |
1.32e-12 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 67.01 E-value: 1.32e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 10 VILEANKIRKSYGNKlnkqEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNdmtamkekqlae 89
Cdd:COG0488 314 KVLELEGLSKSYGDK----TLLDDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAGELEPDSGTVKLGET------------ 377
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 90 frkQHLGFIFQDYNLLD-TLTVKENIllplsitklskkeanrkfEEVAKELGIYELR-------------DKYPNEISGG 155
Cdd:COG0488 378 ---VKIGYFDQHQEELDpDKTVLDEL------------------RDGAPGGTEQEVRgylgrflfsgddaFKPVGVLSGG 436
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 156 QKQRTSAGRAFIHDPSIIFADEPTGALD--SKSAsdLLNKLsqlnQKRNATIIMVTHDPvaasY-----CGRVIFIKDGQ 228
Cdd:COG0488 437 EKARLALAKLLLSPPNVLLLDEPTNHLDieTLEA--LEEAL----DDFPGTVLLVSHDR----YfldrvATRILEFEDGG 506
|
|
| PLN03232 |
PLN03232 |
ABC transporter C family member; Provisional |
20-260 |
1.60e-12 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 67.31 E-value: 1.60e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 20 SYGNKLNKqEVLKGIDIHIEKGEFVSIMGASGSGKTTLLN-VLSSIDQVSHGTIHINGNDMTAmkekqlaefrkQHLGFI 98
Cdd:PLN03232 623 SWDSKTSK-PTLSDINLEIPVGSLVAIVGGTGEGKTSLISaMLGELSHAETSSVVIRGSVAYV-----------PQVSWI 690
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 99 FQdynlldtLTVKENILLPlsitklSKKEANRKFEEV-----AKELGIYELRDKYP-----NEISGGQKQRTSAGRAFIH 168
Cdd:PLN03232 691 FN-------ATVRENILFG------SDFESERYWRAIdvtalQHDLDLLPGRDLTEigergVNISGGQKQRVSMARAVYS 757
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 169 DPSIIFADEPTGALDSKSASDLLNKLSQlNQKRNATIIMVTHDPVAASYCGRVIFIKDGQM-----YTQLNKGGqdrqTF 243
Cdd:PLN03232 758 NSDIYIFDDPLSALDAHVAHQVFDSCMK-DELKGKTRVLVTNQLHFLPLMDRIILVSEGMIkeegtFAELSKSG----SL 832
|
250
....*....|....*..
8G4D_C 244 FQDIMKTQGVLGGVQHE 260
Cdd:PLN03232 833 FKKLMENAGKMDATQEV 849
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
11-228 |
1.95e-12 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 66.57 E-value: 1.95e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 11 ILEANKIRKSY-GNKlnkqeVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMT--AMKEKQL 87
Cdd:PRK10762 4 LLQLKGIDKAFpGVK-----ALSGAALNVYPGRVMALVGENGAGKSTMMKVLTGIYTRDAGSILYLGKEVTfnGPKSSQE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 88 AefrkqHLGFIFQDYNLLDTLTVKENILLPLSIT----KLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAG 163
Cdd:PRK10762 79 A-----GIGIIHQELNLIPQLTIAENIFLGREFVnrfgRIDWKKMYAEADKLLARLNLRFSSDKLVGELSIGEQQMVEIA 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
8G4D_C 164 RAFIHDPSIIFADEPTGAL-DSKSASdLLNKLSQLnQKRNATIIMVTHD-PVAASYCGRVIFIKDGQ 228
Cdd:PRK10762 154 KVLSFESKVIIMDEPTDALtDTETES-LFRVIREL-KSQGRGIVYISHRlKEIFEICDDVTVFRDGQ 218
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
30-210 |
2.57e-12 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 66.59 E-value: 2.57e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 30 VLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVS--HGTIHING--NDMTAMKEKQ-----------LAEFRKQH 94
Cdd:PTZ00265 1183 IYKDLTFSCDSKKTTAIVGETGSGKSTVMSLLMRFYDLKndHHIVFKNEhtNDMTNEQDYQgdeeqnvgmknVNEFSLTK 1262
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 95 LG------FIFQ-------------DYNLLD-----TLTVKENILLPLSI---TKLSKKEANRK-FEEVAKELGIYELRD 146
Cdd:PTZ00265 1263 EGgsgedsTVFKnsgkilldgvdicDYNLKDlrnlfSIVSQEPMLFNMSIyenIKFGKEDATREdVKRACKFAAIDEFIE 1342
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
8G4D_C 147 KYPNE-----------ISGGQKQRTSAGRAFIHDPSIIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTH 210
Cdd:PTZ00265 1343 SLPNKydtnvgpygksLSGGQKQRIAIARALLREPKILLLDEATSSLDSNSEKLIEKTIVDIKDKADKTIITIAH 1417
|
|
| PRK13543 |
PRK13543 |
heme ABC exporter ATP-binding protein CcmA; |
26-215 |
2.91e-12 |
|
heme ABC exporter ATP-binding protein CcmA;
Pssm-ID: 184129 [Multi-domain] Cd Length: 214 Bit Score: 64.10 E-value: 2.91e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 26 NKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGN-DMTAMKEKQLAEFrkQHLGFIFQDynl 104
Cdd:PRK13543 22 NEEPVFGPLDFHVDAGEALLVQGDNGAGKTTLLRVLAGLLHVESGQIQIDGKtATRGDRSRFMAYL--GHLPGLKAD--- 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 105 LDTLtvkENILLplsITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPSIIFADEPTGALDS 184
Cdd:PRK13543 97 LSTL---ENLHF---LCGLHGRRAKQMPGSALAIVGLAGYEDTLVRQLSAGQKKRLALARLWLSPAPLWLLDEPYANLDL 170
|
170 180 190
....*....|....*....|....*....|.
8G4D_C 185 KSASdLLNKLSQLNQKRNATIIMVTHDPVAA 215
Cdd:PRK13543 171 EGIT-LVNRMISAHLRGGGAALVTTHGAYAA 200
|
|
| ABC_CcmA_heme_exporter |
cd03231 |
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ... |
30-212 |
1.02e-11 |
|
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.
Pssm-ID: 213198 [Multi-domain] Cd Length: 201 Bit Score: 62.51 E-value: 1.02e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 30 VLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMtamkeKQLAEFRKQHLGFIFQDYNLLDTLT 109
Cdd:cd03231 15 LFSGLSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVLLNGGPL-----DFQRDSIARGLLYLGHAPGIKTTLS 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 110 VKENillplsITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPSIIFADEPTGALDSKSASD 189
Cdd:cd03231 90 VLEN------LRFWHADHSDEQVEEALARVGLNGFEDRPVAQLSAGQQRRVALARLLLSGRPLWILDEPTTALDKAGVAR 163
|
170 180
....*....|....*....|...
8G4D_C 190 LLNKLSQLNQkRNATIIMVTHDP 212
Cdd:cd03231 164 FAEAMAGHCA-RGGMVVLTTHQD 185
|
|
| 3a01205 |
TIGR00956 |
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other] |
15-246 |
1.14e-11 |
|
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 64.74 E-value: 1.14e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 15 NKIRKSygNKLNKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSH----GTIHINGNDmtamkekqLAEF 90
Cdd:TIGR00956 63 RKLKKF--RDTKTFDILKPMDGLIKPGELTVVLGRPGSGCSTLLKTIASNTDGFHigveGVITYDGIT--------PEEI 132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 91 RKQHLG---FIFQDYNLLDTLTVKENI----------LLPLSITKLSKkeANRKFEEVAKELGIYELRD-KYPNE----I 152
Cdd:TIGR00956 133 KKHYRGdvvYNAETDVHFPHLTVGETLdfaarcktpqNRPDGVSREEY--AKHIADVYMATYGLSHTRNtKVGNDfvrgV 210
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 153 SGGQKQRTSAGRAFIHDPSIIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHDPVAASY--CGRVIFIKDGQmy 230
Cdd:TIGR00956 211 SGGERKRVSIAEASLGGAKIQCWDNATRGLDSATALEFIRALKTSANILDTTPLVAIYQCSQDAYelFDKVIVLYEGY-- 288
|
250
....*....|....*..
8G4D_C 231 tQLNKGGQDR-QTFFQD 246
Cdd:TIGR00956 289 -QIYFGPADKaKQYFEK 304
|
|
| PLN03130 |
PLN03130 |
ABC transporter C family member; Provisional |
26-252 |
1.90e-11 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 63.99 E-value: 1.90e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 26 NKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLN-VLSSIDQVSHGTIHINGndmTAMKEKQLAefrkqhlgFIFQdynl 104
Cdd:PLN03130 628 AERPTLSNINLDVPVGSLVAIVGSTGEGKTSLISaMLGELPPRSDASVVIRG---TVAYVPQVS--------WIFN---- 692
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 105 ldtLTVKENILLPLSITKlSKKEANRKFEEVAKELGIY------ELRDKYPNeISGGQKQRTSAGRAFIHDPSIIFADEP 178
Cdd:PLN03130 693 ---ATVRDNILFGSPFDP-ERYERAIDVTALQHDLDLLpggdltEIGERGVN-ISGGQKQRVSMARAVYSNSDVYIFDDP 767
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
8G4D_C 179 TGALDSKSASDLLNKLSQlNQKRNATIIMVTHDPVAASYCGRVIFIKDGQM-----YTQLNKGGQdrqtFFQDIMKTQG 252
Cdd:PLN03130 768 LSALDAHVGRQVFDKCIK-DELRGKTRVLVTNQLHFLSQVDRIILVHEGMIkeegtYEELSNNGP----LFQKLMENAG 841
|
|
| znuC |
PRK09544 |
high-affinity zinc transporter ATPase; Reviewed |
15-211 |
2.49e-11 |
|
high-affinity zinc transporter ATPase; Reviewed
Pssm-ID: 181939 [Multi-domain] Cd Length: 251 Bit Score: 62.05 E-value: 2.49e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 15 NKIRKSYGNKlnkqEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHingndmtamKEKQLaefrkqH 94
Cdd:PRK09544 8 ENVSVSFGQR----RVLSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGVIK---------RNGKL------R 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 95 LGFIFQDYNLLDTLtvkenillPLSITKLSKKEANRKFEEVA---KELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPS 171
Cdd:PRK09544 69 IGYVPQKLYLDTTL--------PLTVNRFLRLRPGTKKEDILpalKRVQAGHLIDAPMQKLSGGETQRVLLARALLNRPQ 140
|
170 180 190 200
....*....|....*....|....*....|....*....|
8G4D_C 172 IIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHD 211
Cdd:PRK09544 141 LLVLDEPTQGVDVNGQVALYDLIDQLRRELDCAVLMVSHD 180
|
|
| PRK15064 |
PRK15064 |
ABC transporter ATP-binding protein; Provisional |
12-253 |
2.66e-11 |
|
ABC transporter ATP-binding protein; Provisional
Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 62.99 E-value: 2.66e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 12 LEANKIRKSYGNKlnkqEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIhingndmtamkekQLAEfr 91
Cdd:PRK15064 320 LEVENLTKGFDNG----PLFKNLNLLLEAGERLAIIGENGVGKTTLLRTLVGELEPDSGTV-------------KWSE-- 380
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 92 KQHLGFIFQDY--------NLLDTL----TVKENILLPLSIT-KL--SKKEANRKfeevakelgiyelrdkyPNEISGGQ 156
Cdd:PRK15064 381 NANIGYYAQDHaydfendlTLFDWMsqwrQEGDDEQAVRGTLgRLlfSQDDIKKS-----------------VKVLSGGE 443
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 157 KQRTSAGRAFIHDPSIIFADEPTGALDSKSASDLLNKLsqlnQKRNATIIMVTHD-PVAASYCGRVIFIKDGQMytqlnk 235
Cdd:PRK15064 444 KGRMLFGKLMMQKPNVLVMDEPTNHMDMESIESLNMAL----EKYEGTLIFVSHDrEFVSSLATRIIEITPDGV------ 513
|
250
....*....|....*...
8G4D_C 236 ggQDRQTFFQDIMKTQGV 253
Cdd:PRK15064 514 --VDFSGTYEEYLRSQGI 529
|
|
| ABCF_EF-3 |
cd03221 |
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ... |
12-211 |
2.69e-11 |
|
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.
Pssm-ID: 213188 [Multi-domain] Cd Length: 144 Bit Score: 59.77 E-value: 2.69e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 12 LEANKIRKSYGNKLnkqeVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEkQLaefr 91
Cdd:cd03221 1 IELENLSKTYGGKL----LLKDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEGIVTWGSTVKIGYFE-QL---- 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 92 kqhlgfifqdynlldtltvkenillplsitklskkeanrkfeevakelgiyelrdkypneiSGGQKQRTSAGRAFIHDPS 171
Cdd:cd03221 72 -------------------------------------------------------------SGGEKMRLALAKLLLENPN 90
|
170 180 190 200
....*....|....*....|....*....|....*....|
8G4D_C 172 IIFADEPTGALDSKSASDLLNKLSQLNQkrnaTIIMVTHD 211
Cdd:cd03221 91 LLLLDEPTNHLDLESIEALEEALKEYPG----TVILVSHD 126
|
|
| PRK10790 |
PRK10790 |
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein; |
30-239 |
3.01e-11 |
|
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
Pssm-ID: 182733 [Multi-domain] Cd Length: 592 Bit Score: 63.20 E-value: 3.01e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 30 VLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLaefrKQHLGFIFQDYNLL-DTL 108
Cdd:PRK10790 356 VLQNINLSVPSRGFVALVGHTGSGKSTLASLLMGYYPLTEGEIRLDGRPLSSLSHSVL----RQGVAMVQQDPVVLaDTF 431
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 109 TVkeNILL--PLSITKLSKKEANRKFEEVAKEL--GIYELRDKYPNEISGGQKQRTSAGRAFIHDPSIIFADEPTGALDS 184
Cdd:PRK10790 432 LA--NVTLgrDISEEQVWQALETVQLAELARSLpdGLYTPLGEQGNNLSVGQKQLLALARVLVQTPQILILDEATANIDS 509
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
8G4D_C 185 KSASDLLNKLSQLNQK--------RNATI-----IMVTHDPVAASY-CGRVIFIKDG---QMYtQLNKGGQD 239
Cdd:PRK10790 510 GTEQAIQQALAAVREHttlvviahRLSTIveadtILVLHRGQAVEQgTHQQLLAAQGrywQMY-QLQLAGEE 580
|
|
| hmuV |
PRK13547 |
heme ABC transporter ATP-binding protein; |
30-229 |
3.95e-11 |
|
heme ABC transporter ATP-binding protein;
Pssm-ID: 184132 [Multi-domain] Cd Length: 272 Bit Score: 61.77 E-value: 3.95e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 30 VLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLS---SIDQVSHGT-----IHINGNDMTAMKEKQLAEFR-----KQHLG 96
Cdd:PRK13547 16 ILRDLSLRIEPGRVTALLGRNGAGKSTLLKALAgdlTGGGAPRGArvtgdVTLNGEPLAAIDAPRLARLRavlpqAAQPA 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 97 FIFqdynlldtlTVKENILL---PLSITKLSKKEANRKFEEVAKEL-GIYELRDKYPNEISGGQKQRTSAGRAF------ 166
Cdd:PRK13547 96 FAF---------SAREIVLLgryPHARRAGALTHRDGEIAWQALALaGATALVGRDVTTLSGGELARVQFARVLaqlwpp 166
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
8G4D_C 167 ---IHDPSIIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHDP-VAASYCGRVIFIKDGQM 229
Cdd:PRK13547 167 hdaAQPPRYLLLDEPTAALDLAHQHRLLDTVRRLARDWNLGVLAIVHDPnLAARHADRIAMLADGAI 233
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
31-229 |
4.48e-11 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 62.66 E-value: 4.48e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 31 LKGIDIHIEKGEFVSIMGASGSGKTTLLN-VLSSIDQVsHGTIHINGNdmtamkekqLAEFRKQhlGFIFQDynlldtlT 109
Cdd:TIGR00957 654 LNGITFSIPEGALVAVVGQVGCGKSSLLSaLLAEMDKV-EGHVHMKGS---------VAYVPQQ--AWIQND-------S 714
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 110 VKENILLPlsiTKLSKKEANRKFEEVA--KELGIY------ELRDKYPNeISGGQKQRTSAGRAFIHDPSIIFADEPTGA 181
Cdd:TIGR00957 715 LRENILFG---KALNEKYYQQVLEACAllPDLEILpsgdrtEIGEKGVN-LSGGQKQRVSLARAVYSNADIYLFDDPLSA 790
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
8G4D_C 182 LDSKSASDLLNK-LSQLNQKRNATIIMVTHdpvAASYCGRVIFI---KDGQM 229
Cdd:TIGR00957 791 VDAHVGKHIFEHvIGPEGVLKNKTRILVTH---GISYLPQVDVIivmSGGKI 839
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
11-227 |
5.06e-11 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 62.72 E-value: 5.06e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 11 ILEANKIRKSYGNklNKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGND-MTAMKEKQlae 89
Cdd:TIGR01257 1937 ILRLNELTKVYSG--TSSPAVDRLCVGVRPGECFGLLGVNGAGKTTTFKMLTGDTTVTSGDATVAGKSiLTNISDVH--- 2011
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 90 frkQHLGFIFQDYNLLDTLTVKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHD 169
Cdd:TIGR01257 2012 ---QNMGYCPQFDAIDDLLTGREHLYLYARLRGVPAEEIEKVANWSIQSLGLSLYADRLAGTYSGGNKRKLSTAIALIGC 2088
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
8G4D_C 170 PSIIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHDPVAASYCGRVIFIKDG 227
Cdd:TIGR01257 2089 PPLVLLDEPTTGMDPQARRMLWNTIVSIIREGRAVVLTSHSMEECEALCTRLAIMVKG 2146
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
21-179 |
5.09e-11 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 62.45 E-value: 5.09e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 21 YGnklnKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLAEFR----KQHLG 96
Cdd:NF033858 11 YG----KTVALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRVEVLGGDMADARHRRAVCPRiaymPQGLG 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 97 fifqdYNLLDTLTVKENI-----LLplsitKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPS 171
Cdd:NF033858 87 -----KNLYPTLSVFENLdffgrLF-----GQDAAERRRRIDELLRATGLAPFADRPAGKLSGGMKQKLGLCCALIHDPD 156
|
....*...
8G4D_C 172 IIFADEPT 179
Cdd:NF033858 157 LLILDEPT 164
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
32-229 |
6.02e-11 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 62.11 E-value: 6.02e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 32 KGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEkqlAEFRKQHLGFIFQ---DYNLLDTL 108
Cdd:PRK09700 280 RDISFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRAGGEIRLNGKDISPRSP---LDAVKKGMAYITEsrrDNGFFPNF 356
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 109 TVKENILLPLSITK---------LSKKEANRKFEEVAKELGIY-ELRDKYPNEISGGQKQRTSAGRAFIHDPSIIFADEP 178
Cdd:PRK09700 357 SIAQNMAISRSLKDggykgamglFHEVDEQRTAENQRELLALKcHSVNQNITELSGGNQQKVLISKWLCCCPEVIIFDEP 436
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
8G4D_C 179 TGALDSKSASDLLNKLSQLNQKrNATIIMVTHD-PVAASYCGRVIFIKDGQM 229
Cdd:PRK09700 437 TRGIDVGAKAEIYKVMRQLADD-GKVILMVSSElPEIITVCDRIAVFCEGRL 487
|
|
| cbiO |
PRK13638 |
energy-coupling factor ABC transporter ATP-binding protein; |
28-211 |
7.65e-11 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184198 [Multi-domain] Cd Length: 271 Bit Score: 60.79 E-value: 7.65e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 28 QEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLAefRKQHLGFIFQD------ 101
Cdd:PRK13638 14 EPVLKGLNLDFSLSPVTGLVGANGCGKSTLFMNLSGLLRPQKGAVLWQGKPLDYSKRGLLA--LRQQVATVFQDpeqqif 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 102 YNLLDTltvkeNILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPSIIFADEPTGA 181
Cdd:PRK13638 92 YTDIDS-----DIAFSLRNLGVPEAEITRRVDEALTLVDAQHFRHQPIQCLSHGQKKRVAIAGALVLQARYLLLDEPTAG 166
|
170 180 190
....*....|....*....|....*....|
8G4D_C 182 LDSKSASDLLNKLSQLNQKRNATIIMvTHD 211
Cdd:PRK13638 167 LDPAGRTQMIAIIRRIVAQGNHVIIS-SHD 195
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
29-210 |
1.03e-10 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 61.58 E-value: 1.03e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 29 EVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINgnDMTAMKEKQLAEFRKQhLGFIFQDyNLLDTL 108
Cdd:PTZ00265 399 EIYKDLNFTLTEGKTYAFVGESGCGKSTILKLIERLYDPTEGDIIIN--DSHNLKDINLKWWRSK-IGVVSQD-PLLFSN 474
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 109 TVKENILLPL-------------------------------------------SITKLSKKEANRKFE--------EVAK 137
Cdd:PTZ00265 475 SIKNNIKYSLyslkdlealsnyynedgndsqenknkrnscrakcagdlndmsnTTDSNELIEMRKNYQtikdsevvDVSK 554
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 138 ELGIYE----LRDKY-------PNEISGGQKQRTSAGRAFIHDPSIIFADEPTGALDSKSASDLLNKLSQLNQKRNATII 206
Cdd:PTZ00265 555 KVLIHDfvsaLPDKYetlvgsnASKLSGGQKQRISIARAIIRNPKILILDEATSSLDNKSEYLVQKTINNLKGNENRITI 634
|
....
8G4D_C 207 MVTH 210
Cdd:PTZ00265 635 IIAH 638
|
|
| PRK15093 |
PRK15093 |
peptide ABC transporter ATP-binding protein SapD; |
34-222 |
1.13e-10 |
|
peptide ABC transporter ATP-binding protein SapD;
Pssm-ID: 185049 [Multi-domain] Cd Length: 330 Bit Score: 60.97 E-value: 1.13e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 34 IDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQ----VSHGTIHINGNDMTAMKEKQLAEFRKQHLGFIFQDYNllDTLT 109
Cdd:PRK15093 26 VSMTLTEGEIRGLVGESGSGKSLIAKAICGVTKdnwrVTADRMRFDDIDLLRLSPRERRKLVGHNVSMIFQEPQ--SCLD 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 110 VKENILLPL--SITKLSKKEA--------NRKFEEVAKELGIYELRD---KYPNEISGGQKQRTSAGRAFIHDPSIIFAD 176
Cdd:PRK15093 104 PSERVGRQLmqNIPGWTYKGRwwqrfgwrKRRAIELLHRVGIKDHKDamrSFPYELTEGECQKVMIAIALANQPRLLIAD 183
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
8G4D_C 177 EPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHDPVAAS---------YCGRVI 222
Cdd:PRK15093 184 EPTNAMEPTTQAQIFRLLTRLNQNNNTTILLISHDLQMLSqwadkinvlYCGQTV 238
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
38-210 |
4.03e-10 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 59.75 E-value: 4.03e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 38 IEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIH-----INGNDMtamkekqlaEFRKQhLGFIFQDYNLLDTLTVKE 112
Cdd:NF033858 289 IRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAWlfgqpVDAGDI---------ATRRR-VGYMSQAFSLYGELTVRQ 358
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 113 NILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPSIIFADEPTGALDSkSASD--- 189
Cdd:NF033858 359 NLELHARLFHLPAAEIAARVAEMLERFDLADVADALPDSLPLGIRQRLSLAVAVIHKPELLILDEPTSGVDP-VARDmfw 437
|
170 180
....*....|....*....|..
8G4D_C 190 -LLNKLSqlnQKRNATIIMVTH 210
Cdd:NF033858 438 rLLIELS---REDGVTIFISTH 456
|
|
| PRK15056 |
PRK15056 |
manganese/iron ABC transporter ATP-binding protein; |
26-225 |
4.55e-10 |
|
manganese/iron ABC transporter ATP-binding protein;
Pssm-ID: 185016 [Multi-domain] Cd Length: 272 Bit Score: 58.74 E-value: 4.55e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 26 NKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLAEFRKQHlgfifQDYNLL 105
Cdd:PRK15056 18 NGHTALRDASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLASGKISILGQPTRQALQKNLVAYVPQS-----EEVDWS 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 106 DTLTVKENILLP----LSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPSIIFADEPTGA 181
Cdd:PRK15056 93 FPVLVEDVVMMGryghMGWLRRAKKRDRQIVTAALARVDMVEFRHRQIGELSGGQKKRVFLARAIAQQGQVILLDEPFTG 172
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
8G4D_C 182 LDSKSASDLLNKLSQLnQKRNATIIMVTHDPVAAS-YCGRVIFIK 225
Cdd:PRK15056 173 VDVKTEARIISLLREL-RDEGKTMLVSTHNLGSVTeFCDYTVMVK 216
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
30-209 |
4.98e-10 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 59.54 E-value: 4.98e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 30 VLKGIDIHIEKGEFVSIMGASGSGKTTLLnvlssidqvshgtihingndMTAMKEKQLAEFRKQHLGFIF--QDYNLLDT 107
Cdd:TIGR01271 441 VLKNISFKLEKGQLLAVAGSTGSGKSSLL--------------------MMIMGELEPSEGKIKHSGRISfsPQTSWIMP 500
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 108 LTVKENILLPLSITKLskkeanrKFEEVAKELGIYELRDKYPNE-----------ISGGQKQRTSAGRAFIHDPSIIFAD 176
Cdd:TIGR01271 501 GTIKDNIIFGLSYDEY-------RYTSVIKACQLEEDIALFPEKdktvlgeggitLSGGQRARISLARAVYKDADLYLLD 573
|
170 180 190
....*....|....*....|....*....|....
8G4D_C 177 EPTGALDSKSASDLLNK-LSQLnqKRNATIIMVT 209
Cdd:TIGR01271 574 SPFTHLDVVTEKEIFEScLCKL--MSNKTRILVT 605
|
|
| ABC_RNaseL_inhibitor_domain2 |
cd03237 |
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
38-228 |
9.88e-10 |
|
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213204 [Multi-domain] Cd Length: 246 Bit Score: 57.42 E-value: 9.88e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 38 IEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTamkekqlaeFRKQhlgFIFQDYnlldTLTVKEnilLP 117
Cdd:cd03237 22 ISESEVIGILGPNGIGKTTFIKMLAGVLKPDEGDIEIELDTVS---------YKPQ---YIKADY----EGTVRD---LL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 118 LSITKlSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPSIIFADEPTGALDSKS---ASDLLNKL 194
Cdd:cd03237 83 SSITK-DFYTHPYFKTEIAKPLQIEQILDREVPELSGGELQRVAIAACLSKDADIYLLDEPSAYLDVEQrlmASKVIRRF 161
|
170 180 190
....*....|....*....|....*....|....
8G4D_C 195 SQLNQKrnaTIIMVTHDPVAASYCGRVIFIKDGQ 228
Cdd:cd03237 162 AENNEK---TAFVVEHDIIMIDYLADRLIVFEGE 192
|
|
| PLN03140 |
PLN03140 |
ABC transporter G family member; Provisional |
19-188 |
1.12e-09 |
|
ABC transporter G family member; Provisional
Pssm-ID: 215599 [Multi-domain] Cd Length: 1470 Bit Score: 58.70 E-value: 1.12e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 19 KSYGNKLNKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSH--GTIHINGndmTAMKEKQLAEFRkqhlG 96
Cdd:PLN03140 884 KEQGVTEDRLQLLREVTGAFRPGVLTALMGVSGAGKTTLMDVLAGRKTGGYieGDIRISG---FPKKQETFARIS----G 956
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 97 FIFQDYNLLDTLTVKENIL------LPlsiTKLSKKEANRKFEEVAKELGIYELRDK---YP--NEISGGQKQRTSAGRA 165
Cdd:PLN03140 957 YCEQNDIHSPQVTVRESLIysaflrLP---KEVSKEEKMMFVDEVMELVELDNLKDAivgLPgvTGLSTEQRKRLTIAVE 1033
|
170 180
....*....|....*....|...
8G4D_C 166 FIHDPSIIFADEPTGALDSKSAS 188
Cdd:PLN03140 1034 LVANPSIIFMDEPTSGLDARAAA 1056
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
10-211 |
1.17e-09 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 58.28 E-value: 1.17e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 10 VILEANKIRKSYGN-KLnkqEVLKGidiHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIhingndmtaMKEKQLA 88
Cdd:PRK13409 339 TLVEYPDLTKKLGDfSL---EVEGG---EIYEGEVIGIVGPNGIGKTTFAKLLAGVLKPDEGEV---------DPELKIS 403
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 89 eFRKQhlgFIFQDYNLldtlTVKENILlplSITklSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIH 168
Cdd:PRK13409 404 -YKPQ---YIKPDYDG----TVEDLLR---SIT--DDLGSSYYKSEIIKPLQLERLLDKNVKDLSGGELQRVAIAACLSR 470
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
8G4D_C 169 DPSIIFADEPTGALDSK---SASDLLNKLSqlnQKRNATIIMVTHD 211
Cdd:PRK13409 471 DADLYLLDEPSAHLDVEqrlAVAKAIRRIA---EEREATALVVDHD 513
|
|
| ycf16 |
CHL00131 |
sulfate ABC transporter protein; Validated |
25-210 |
1.71e-09 |
|
sulfate ABC transporter protein; Validated
Pssm-ID: 214372 [Multi-domain] Cd Length: 252 Bit Score: 56.57 E-value: 1.71e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 25 LNKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSID--QVSHGTIHING---NDMTAMKEKQLAEFrkqhLGF-- 97
Cdd:CHL00131 17 VNENEILKGLNLSINKGEIHAIMGPNGSGKSTLSKVIAGHPayKILEGDILFKGesiLDLEPEERAHLGIF----LAFqy 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 98 ---------------------IFQDYNLLDTLTVKENILLPLSITKLSKKEANRkfeevakelgiyelrdkYPNE-ISGG 155
Cdd:CHL00131 93 pieipgvsnadflrlaynskrKFQGLPELDPLEFLEIINEKLKLVGMDPSFLSR-----------------NVNEgFSGG 155
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
8G4D_C 156 QKQRTSAGRAFIHDPSIIFADEPTGALDS---KSASDLLNKLSQLNQkrnaTIIMVTH 210
Cdd:CHL00131 156 EKKRNEILQMALLDSELAILDETDSGLDIdalKIIAEGINKLMTSEN----SIILITH 209
|
|
| ABCC_CFTR1 |
cd03291 |
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ... |
30-183 |
2.12e-09 |
|
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213258 [Multi-domain] Cd Length: 282 Bit Score: 56.79 E-value: 2.12e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 30 VLKGIDIHIEKGEFVSIMGASGSGKTTLLnvlssidqvshgtihingndMTAMKEKQLAEFRKQHLGFI--FQDYNLLDT 107
Cdd:cd03291 52 VLKNINLKIEKGEMLAITGSTGSGKTSLL--------------------MLILGELEPSEGKIKHSGRIsfSSQFSWIMP 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 108 LTVKENILLPLSITKLskkeanrKFEEVAKELGIYELRDKYPNE-----------ISGGQKQRTSAGRAFIHDPSIIFAD 176
Cdd:cd03291 112 GTIKENIIFGVSYDEY-------RYKSVVKACQLEEDITKFPEKdntvlgeggitLSGGQRARISLARAVYKDADLYLLD 184
|
....*..
8G4D_C 177 EPTGALD 183
Cdd:cd03291 185 SPFGYLD 191
|
|
| ABCC_CFTR2 |
cd03289 |
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ... |
30-247 |
2.97e-09 |
|
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213256 [Multi-domain] Cd Length: 275 Bit Score: 56.40 E-value: 2.97e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 30 VLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQvSHGTIHINGNDMTAMKekqLAEFRKQhLGFIFQDYNLLdTLT 109
Cdd:cd03289 19 VLENISFSISPGQRVGLLGRTGSGKSTLLSAFLRLLN-TEGDIQIDGVSWNSVP---LQKWRKA-FGVIPQKVFIF-SGT 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 110 VKENiLLPLSitklskKEANRKFEEVAKELGIYELRDKYPNE-----------ISGGQKQRTSAGRAFIHDPSIIFADEP 178
Cdd:cd03289 93 FRKN-LDPYG------KWSDEEIWKVAEEVGLKSVIEQFPGQldfvlvdggcvLSHGHKQLMCLARSVLSKAKILLLDEP 165
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
8G4D_C 179 TGALDSKSASDLLNKLSQlnQKRNATIIMVTHDPVAASYCGRVIFIKDGQM--YTQLNKGGQDRQTFFQDI 247
Cdd:cd03289 166 SAHLDPITYQVIRKTLKQ--AFADCTVILSEHRIEAMLECQRFLVIEENKVrqYDSIQKLLNEKSHFKQAI 234
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
39-211 |
4.07e-09 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 56.72 E-value: 4.07e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 39 EKGEFVSIMGASGSGKTTLLNVLSsidqvshGTIHIN-GN-DMTAMKEKQLAEFRkqhlGFIFQDY--NLLD-TLTVKEN 113
Cdd:COG1245 97 KKGKVTGILGPNGIGKSTALKILS-------GELKPNlGDyDEEPSWDEVLKRFR----GTELQDYfkKLANgEIKVAHK 165
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 114 I----LLPLSIT----KLSKKEANR-KFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPSIIFADEPTGALDS 184
Cdd:COG1245 166 PqyvdLIPKVFKgtvrELLEKVDERgKLDELAEKLGLENILDRDISELSGGELQRVAIAAALLRDADFYFFDEPSSYLDI 245
|
170 180 190
....*....|....*....|....*....|
8G4D_C 185 K---SASDLLNKLSqlnqKRNATIIMVTHD 211
Cdd:COG1245 246 YqrlNVARLIRELA----EEGKYVLVVEHD 271
|
|
| ABC_RNaseL_inhibitor_domain1 |
cd03236 |
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
41-211 |
5.58e-09 |
|
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213203 [Multi-domain] Cd Length: 255 Bit Score: 55.07 E-value: 5.58e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 41 GEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEkqlaeFRKQHLgfifQDY--NLLDTlTVKENI---- 114
Cdd:cd03236 26 GQVLGLVGPNGIGKSTALKILAGKLKPNLGKFDDPPDWDEILDE-----FRGSEL----QNYftKLLEG-DVKVIVkpqy 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 115 --LLPLSITK-----LSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPSIIFADEPTGALDSKSA 187
Cdd:cd03236 96 vdLIPKAVKGkvgelLKKKDERGKLDELVDQLELRHVLDRNIDQLSGGELQRVAIAAALARDADFYFFDEPSSYLDIKQR 175
|
170 180
....*....|....*....|....
8G4D_C 188 SDLLNKLSQLNQKRNAtIIMVTHD 211
Cdd:cd03236 176 LNAARLIRELAEDDNY-VLVVEHD 198
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
15-211 |
6.23e-09 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 55.90 E-value: 6.23e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 15 NKIRKSYGNKlnkQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGtihingndmtamkEKQLAEFRKqh 94
Cdd:PRK11819 10 NRVSKVVPPK---KQILKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVDKEFEG-------------EARPAPGIK-- 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 95 LGFIFQDYNLLDTLTVKENILLPLSITKLSKKEANR----------KFEEVAKELGIYE--------------------- 143
Cdd:PRK11819 72 VGYLPQEPQLDPEKTVRENVEEGVAEVKAALDRFNEiyaayaepdaDFDALAAEQGELQeiidaadawdldsqleiamda 151
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
8G4D_C 144 LR----DKYPNEISGGQKQRTSAGRAFIHDPSIIFADEPTGALDSKSASDLLNKLsqlnQKRNATIIMVTHD 211
Cdd:PRK11819 152 LRcppwDAKVTKLSGGERRRVALCRLLLEKPDMLLLDEPTNHLDAESVAWLEQFL----HDYPGTVVAVTHD 219
|
|
| PLN03232 |
PLN03232 |
ABC transporter C family member; Provisional |
30-229 |
1.10e-08 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 55.75 E-value: 1.10e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 30 VLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKekqLAEFRKQhLGFIFQDyNLLDTLT 109
Cdd:PLN03232 1251 VLHGLSFFVSPSEKVGVVGRTGAGKSSMLNALFRIVELEKGRIMIDDCDVAKFG---LTDLRRV-LSIIPQS-PVLFSGT 1325
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 110 VKENIlLPLSitklskKEANRKFEEVAKELGIYELRDKYP-----------NEISGGQKQRTSAGRAFIHDPSIIFADEP 178
Cdd:PLN03232 1326 VRFNI-DPFS------EHNDADLWEALERAHIKDVIDRNPfgldaevseggENFSVGQRQLLSLARALLRRSKILVLDEA 1398
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
8G4D_C 179 TGALDSKsaSDLLNKLSQLNQKRNATIIMVTHDPVAASYCGRVIFIKDGQM 229
Cdd:PLN03232 1399 TASVDVR--TDSLIQRTIREEFKSCTMLVIAHRLNTIIDCDKILVLSSGQV 1447
|
|
| PTZ00243 |
PTZ00243 |
ABC transporter; Provisional |
30-210 |
1.17e-08 |
|
ABC transporter; Provisional
Pssm-ID: 240327 [Multi-domain] Cd Length: 1560 Bit Score: 55.56 E-value: 1.17e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 30 VLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKekqLAEFRKQhLGFIFQDYNLLDTlT 109
Cdd:PTZ00243 1325 VLRGVSFRIAPREKVGIVGRTGSGKSTLLLTFMRMVEVCGGEIRVNGREIGAYG---LRELRRQ-FSMIPQDPVLFDG-T 1399
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 110 VKENiLLPLSitklskkEANRkfEEVAKELGIYELRDKYPNEISG--------------GQKQRTSAGRAFIHDPS-IIF 174
Cdd:PTZ00243 1400 VRQN-VDPFL-------EASS--AEVWAALELVGLRERVASESEGidsrvleggsnysvGQRQLMCMARALLKKGSgFIL 1469
|
170 180 190 200
....*....|....*....|....*....|....*....|
8G4D_C 175 ADEPTG----ALDSKSASDLLNKLSqlnqkrNATIIMVTH 210
Cdd:PTZ00243 1470 MDEATAnidpALDRQIQATVMSAFS------AYTVITIAH 1503
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
31-228 |
1.72e-08 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 54.74 E-value: 1.72e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 31 LKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLAEfrkQHLGFIFQDYNLLDTLTV 110
Cdd:PRK10982 14 LDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGSILFQGKEIDFKSSKEALE---NGISMVHQELNLVLQRSV 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 111 KENILL---PLSITKLSKKEANRKFEEVAKELGI-YELRDKYPNeISGGQKQRTSAGRAFIHDPSIIFADEPTGALDSKS 186
Cdd:PRK10982 91 MDNMWLgryPTKGMFVDQDKMYRDTKAIFDELDIdIDPRAKVAT-LSVSQMQMIEIAKAFSYNAKIVIMDEPTSSLTEKE 169
|
170 180 190 200
....*....|....*....|....*....|....*....|...
8G4D_C 187 ASDLLNKLSQLnQKRNATIIMVTHD-PVAASYCGRVIFIKDGQ 228
Cdd:PRK10982 170 VNHLFTIIRKL-KERGCGIVYISHKmEEIFQLCDEITILRDGQ 211
|
|
| PvdE |
COG4615 |
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion ... |
34-108 |
2.06e-08 |
|
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion transport and metabolism];
Pssm-ID: 443659 [Multi-domain] Cd Length: 547 Bit Score: 54.42 E-value: 2.06e-08
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
8G4D_C 34 IDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAmkeKQLAEFRkQHLGFIFQDYNLLDTL 108
Cdd:COG4615 351 IDLTIRRGELVFIVGGNGSGKSTLAKLLTGLYRPESGEILLDGQPVTA---DNREAYR-QLFSAVFSDFHLFDRL 421
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
30-247 |
3.52e-08 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 54.15 E-value: 3.52e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 30 VLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQvSHGTIHING---NDMTamkekqLAEFRKQhLGFIFQDYNLLd 106
Cdd:TIGR01271 1234 VLQDLSFSVEGGQRVGLLGRTGSGKSTLLSALLRLLS-TEGEIQIDGvswNSVT------LQTWRKA-FGVIPQKVFIF- 1304
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 107 TLTVKENiLLPLSitKLSKKEANRkfeeVAKELGIYELRDKYPNE-----------ISGGQKQRTSAGRAFIHDPSIIFA 175
Cdd:TIGR01271 1305 SGTFRKN-LDPYE--QWSDEEIWK----VAEEVGLKSVIEQFPDKldfvlvdggyvLSNGHKQLMCLARSILSKAKILLL 1377
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
8G4D_C 176 DEPTGALDSKSASDLLNKLSQlnQKRNATIIMVTHDPVAASYCGRVIFIKDGQM--YTQLNKGGQDRQTFFQDI 247
Cdd:TIGR01271 1378 DEPSAHLDPVTLQIIRKTLKQ--SFSNCTVILSEHRVEALLECQQFLVIEGSSVkqYDSIQKLLNETSLFKQAM 1449
|
|
| GguA |
NF040905 |
sugar ABC transporter ATP-binding protein; |
11-210 |
4.68e-08 |
|
sugar ABC transporter ATP-binding protein;
Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 53.25 E-value: 4.68e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 11 ILEANKIRKSY-GNKlnkqeVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIdqVSHGT----IHINGndmtamkek 85
Cdd:NF040905 1 ILEMRGITKTFpGVK-----ALDDVNLSVREGEIHALCGENGAGKSTLMKVLSGV--YPHGSyegeILFDG--------- 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 86 QLAEFRK----QHLGF--IFQDYNLLDTLTVKENILLPLSITK---LSKKEANRKFEEVAKELGIYELRDKYPNEISGGQ 156
Cdd:NF040905 65 EVCRFKDirdsEALGIviIHQELALIPYLSIAENIFLGNERAKrgvIDWNETNRRARELLAKVGLDESPDTLVTDIGVGK 144
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
8G4D_C 157 KQRTSAGRAFIHDPSIIFADEPTGALDSKSASDLLNKLSQLnQKRNATIIMVTH 210
Cdd:NF040905 145 QQLVEIAKALSKDVKLLILDEPTAALNEEDSAALLDLLLEL-KAQGITSIIISH 197
|
|
| PTZ00243 |
PTZ00243 |
ABC transporter; Provisional |
24-242 |
5.49e-08 |
|
ABC transporter; Provisional
Pssm-ID: 240327 [Multi-domain] Cd Length: 1560 Bit Score: 53.63 E-value: 5.49e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 24 KLNKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIhingndmtaMKEKQLAEFRKQhlGFIFQdyn 103
Cdd:PTZ00243 669 ELEPKVLLRDVSVSVPRGKLTVVLGATGSGKSTLLQSLLSQFEISEGRV---------WAERSIAYVPQQ--AWIMN--- 734
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 104 lldtLTVKENILL--PLSITKLSKKEANRKFEEVAKELGI---YELRDKYPNeISGGQKQRTSAGRAFIHDPSIIFADEP 178
Cdd:PTZ00243 735 ----ATVRGNILFfdEEDAARLADAVRVSQLEADLAQLGGgleTEIGEKGVN-LSGGQKARVSLARAVYANRDVYLLDDP 809
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
8G4D_C 179 TGALDSKSASDLLNKLSqLNQKRNATIIMVTH--------DPVAASYCGRVIFIKDGQ------MYTQLNKGGQDRQT 242
Cdd:PTZ00243 810 LSALDAHVGERVVEECF-LGALAGKTRVLATHqvhvvpraDYVVALGDGRVEFSGSSAdfmrtsLYATLAAELKENKD 886
|
|
| ABC_UvrA |
cd03238 |
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in ... |
31-228 |
6.38e-08 |
|
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.
Pssm-ID: 213205 [Multi-domain] Cd Length: 176 Bit Score: 51.17 E-value: 6.38e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 31 LKGIDIHIEKGEFVSIMGASGSGKTTLLNvlssidqvshGTIHINGndmTAMKEKQLAEFRKQHLGFIFQDYNLLDTltv 110
Cdd:cd03238 11 LQNLDVSIPLNVLVVVTGVSGSGKSTLVN----------EGLYASG---KARLISFLPKFSRNKLIFIDQLQFLIDV--- 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 111 keNI-LLPLsitklskkeaNRKFeevakelgiyelrdkypNEISGGQKQRTS-AGRAFIHDPSIIFA-DEPTGALDSKSA 187
Cdd:cd03238 75 --GLgYLTL----------GQKL-----------------STLSGGELQRVKlASELFSEPPGTLFIlDEPSTGLHQQDI 125
|
170 180 190 200
....*....|....*....|....*....|....*....|.
8G4D_C 188 SDLLNKLSQLNQKRNaTIIMVTHDPVAASYCGRVIFIKDGQ 228
Cdd:cd03238 126 NQLLEVIKGLIDLGN-TVILIEHNLDVLSSADWIIDFGPGS 165
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
38-211 |
6.67e-08 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 52.89 E-value: 6.67e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 38 IEKGEFVSIMGASGSGKTTLLNVLSsidqvshGTIHIN-GN-DMTAMKEKQLAEFRkqhlGFIFQDY--NLLD-TLTVKE 112
Cdd:PRK13409 96 PKEGKVTGILGPNGIGKTTAVKILS-------GELIPNlGDyEEEPSWDEVLKRFR----GTELQNYfkKLYNgEIKVVH 164
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 113 NI----LLPLSITK-----LSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPSIIFADEPTGALD 183
Cdd:PRK13409 165 KPqyvdLIPKVFKGkvrelLKKVDERGKLDEVVERLGLENILDRDISELSGGELQRVAIAAALLRDADFYFFDEPTSYLD 244
|
170 180 190
....*....|....*....|....*....|.
8G4D_C 184 SK---SASDLLNKLSQlnqkrNATIIMVTHD 211
Cdd:PRK13409 245 IRqrlNVARLIRELAE-----GKYVLVVEHD 270
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
35-211 |
7.17e-08 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 53.03 E-value: 7.17e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 35 DIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTI-----------------HINGN--DMTAMKEKQLAEFRKQH- 94
Cdd:PRK11147 23 ELHIEDNERVCLVGRNGAGKSTLMKILNGEVLLDDGRIiyeqdlivarlqqdpprNVEGTvyDFVAEGIEEQAEYLKRYh 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 95 --LGFIFQDYN--LLDTLTVKENILLPLSITKLSKkeanrKFEEVAKELGIYElrDKYPNEISGGQKQRTSAGRAFIHDP 170
Cdd:PRK11147 103 diSHLVETDPSekNLNELAKLQEQLDHHNLWQLEN-----RINEVLAQLGLDP--DAALSSLSGGWLRKAALGRALVSNP 175
|
170 180 190 200
....*....|....*....|....*....|....*....|.
8G4D_C 171 SIIFADEPTGALDsksaSDLLNKLSQLNQKRNATIIMVTHD 211
Cdd:PRK11147 176 DVLLLDEPTNHLD----IETIEWLEGFLKTFQGSIIFISHD 212
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
30-210 |
7.41e-08 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 53.03 E-value: 7.41e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 30 VLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKekqLAEFRKQhLGFIFQDyNLLDTLT 109
Cdd:TIGR00957 1301 VLRHINVTIHGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGLNIAKIG---LHDLRFK-ITIIPQD-PVLFSGS 1375
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 110 VKENiLLPLSitKLSKKEANRKFEEVAKELGIYELRDKYPNE-------ISGGQKQRTSAGRAFIHDPSIIFADEPTGAL 182
Cdd:TIGR00957 1376 LRMN-LDPFS--QYSDEEVWWALELAHLKTFVSALPDKLDHEcaeggenLSVGQRQLVCLARALLRKTKILVLDEATAAV 1452
|
170 180
....*....|....*....|....*...
8G4D_C 183 DSKsaSDLLNKLSQLNQKRNATIIMVTH 210
Cdd:TIGR00957 1453 DLE--TDNLIQSTIRTQFEDCTVLTIAH 1478
|
|
| PRK10522 |
PRK10522 |
multidrug transporter membrane component/ATP-binding component; Provisional |
31-230 |
1.55e-07 |
|
multidrug transporter membrane component/ATP-binding component; Provisional
Pssm-ID: 236707 [Multi-domain] Cd Length: 547 Bit Score: 51.90 E-value: 1.55e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 31 LKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAmkeKQLAEFRkQHLGFIFQDYNLLDTLTV 110
Cdd:PRK10522 339 VGPINLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEILLDGKPVTA---EQPEDYR-KLFSAVFTDFHLFDQLLG 414
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 111 KENillplsitklskKEANRkfEEVAKELGIYELRDKYPNE--------ISGGQKQRTSAGRAFIHDPSIIFADEPTGAL 182
Cdd:PRK10522 415 PEG------------KPANP--ALVEKWLERLKMAHKLELEdgrisnlkLSKGQKKRLALLLALAEERDILLLDEWAADQ 480
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
8G4D_C 183 DSKSASDLLNKLSQLNQKRNATIIMVTHDPVAASYCGRVIFIKDGQMY 230
Cdd:PRK10522 481 DPHFRREFYQVLLPLLQEMGKTIFAISHDDHYFIHADRLLEMRNGQLS 528
|
|
| PRK03695 |
PRK03695 |
vitamin B12-transporter ATPase; Provisional |
38-232 |
2.98e-07 |
|
vitamin B12-transporter ATPase; Provisional
Pssm-ID: 235150 [Multi-domain] Cd Length: 248 Bit Score: 49.93 E-value: 2.98e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 38 IEKGEFVSIMGASGSGKTTLLNVLSSIdQVSHGTIHINGNDMTAMKEKQLAEFRkqhlGFIFQDYNLLDTLTVKEniLLP 117
Cdd:PRK03695 19 VRAGEILHLVGPNGAGKSTLLARMAGL-LPGSGSIQFAGQPLEAWSAAELARHR----AYLSQQQTPPFAMPVFQ--YLT 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 118 LSITKLSKKEANRK-FEEVAKELGiyeLRDKYP---NEISGGQKQRTSAGRAFIH-DPSI------IFADEPTGALD--S 184
Cdd:PRK03695 92 LHQPDKTRTEAVASaLNEVAEALG---LDDKLGrsvNQLSGGEWQRVRLAAVVLQvWPDInpagqlLLLDEPMNSLDvaQ 168
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
8G4D_C 185 KSASD-LLNKLSQLnqkrNATIIMVTHD-PVAASYCGRVIFIKDGQMYTQ 232
Cdd:PRK03695 169 QAALDrLLSELCQQ----GIAVVMSSHDlNHTLRHADRVWLLKQGKLLAS 214
|
|
| 3a01203 |
TIGR00954 |
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, ... |
26-212 |
3.12e-07 |
|
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 273360 [Multi-domain] Cd Length: 659 Bit Score: 50.90 E-value: 3.12e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 26 NKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINgndmtamkekqlaefRKQHLGFIFQD-YNL 104
Cdd:TIGR00954 463 NGDVLIESLSFEVPSGNNLLICGPNGCGKSSLFRILGELWPVYGGRLTKP---------------AKGKLFYVPQRpYMT 527
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 105 LDTLtvKENILLPLSITK-----LSKKEANRKFEEV------AKELGIYELRDkYPNEISGGQKQRTSAGRAFIHDPSII 173
Cdd:TIGR00954 528 LGTL--RDQIIYPDSSEDmkrrgLSDKDLEQILDNVqlthilEREGGWSAVQD-WMDVLSGGEKQRIAMARLFYHKPQFA 604
|
170 180 190
....*....|....*....|....*....|....*....
8G4D_C 174 FADEPTGALdsksASDLLNKLSQLNQKRNATIIMVTHDP 212
Cdd:TIGR00954 605 ILDECTSAV----SVDVEGYMYRLCREFGITLFSVSHRK 639
|
|
| PRK10938 |
PRK10938 |
putative molybdenum transport ATP-binding protein ModF; Provisional |
35-200 |
3.34e-07 |
|
putative molybdenum transport ATP-binding protein ModF; Provisional
Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 50.78 E-value: 3.34e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 35 DIHIEKGEFVSIMGASGSGKTTLLNVLSsidqvshgtihingNDMTAMKEKQLAEFRK-QHLGF---------IFQDYN- 103
Cdd:PRK10938 23 SLTLNAGDSWAFVGANGSGKSALARALA--------------GELPLLSGERQSQFSHiTRLSFeqlqklvsdEWQRNNt 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 104 -LL-----DT-LTVKENILLplsitklSKKEANRkFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPSIIFAD 176
Cdd:PRK10938 89 dMLspgedDTgRTTAEIIQD-------EVKDPAR-CEQLAQQFGITALLDRRFKYLSTGETRKTLLCQALMSEPDLLILD 160
|
170 180
....*....|....*....|....
8G4D_C 177 EPTGALDSKSASDLLNKLSQLNQK 200
Cdd:PRK10938 161 EPFDGLDVASRQQLAELLASLHQS 184
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
10-183 |
3.63e-07 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 50.70 E-value: 3.63e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 10 VILEANKIRKSYGNKLnkqeVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHInGNDMtamkekqlae 89
Cdd:TIGR03719 321 KVIEAENLTKAFGDKL----LIDDLSFKLPPGGIVGVIGPNGAGKSTLFRMITGQEQPDSGTIEI-GETV---------- 385
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 90 frkqHLGFIFQDYNLLD-TLTVKENILLPLSITKLSKKEAN-RKFeevakeLGIYELR----DKYPNEISGGQKQRTSAG 163
Cdd:TIGR03719 386 ----KLAYVDQSRDALDpNKTVWEEISGGLDIIKLGKREIPsRAY------VGRFNFKgsdqQKKVGQLSGGERNRVHLA 455
|
170 180
....*....|....*....|
8G4D_C 164 RAFIHDPSIIFADEPTGALD 183
Cdd:TIGR03719 456 KTLKSGGNVLLLDEPTNDLD 475
|
|
| 40850658_otr |
NF000106 |
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit; |
106-210 |
7.26e-07 |
|
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
Pssm-ID: 411078 [Multi-domain] Cd Length: 351 Bit Score: 49.35 E-value: 7.26e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 106 DTLTVKENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPSIIFADEPTGALDSK 185
Cdd:NF000106 99 ESFSGRENLYMIGR*LDLSRKDARARADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPTTGLDPR 178
|
90 100
....*....|....*....|....*
8G4D_C 186 SASDLLNKLSQLnQKRNATIIMVTH 210
Cdd:NF000106 179 TRNEVWDEVRSM-VRDGATVLLTTQ 202
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
40-212 |
9.53e-07 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 47.37 E-value: 9.53e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 40 KGEFVSIMGASGSGKTTLLN-VLSSIDQVSHGTIHINGNDmtamkekqlaefrkqhlgfifqdynlldtltvkenillpl 118
Cdd:smart00382 1 PGEVILIVGPPGSGKTTLARaLARELGPPGGGVIYIDGED---------------------------------------- 40
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 119 sitklskkeanrkFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPSIIFADEPTGALDSKSASDLL-----NK 193
Cdd:smart00382 41 -------------ILEEVLDQLLLIIVGGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLLlleelRL 107
|
170
....*....|....*....
8G4D_C 194 LSQLNQKRNATIIMVTHDP 212
Cdd:smart00382 108 LLLLKSEKNLTVILTTNDE 126
|
|
| ABCC_SUR2 |
cd03288 |
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The ... |
26-227 |
1.03e-06 |
|
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The sulfonylurea receptor SUR is an ATP binding cassette (ABC) protein of the ABCC/MRP family. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.
Pssm-ID: 213255 [Multi-domain] Cd Length: 257 Bit Score: 48.75 E-value: 1.03e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 26 NKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQLaefrKQHLGFIFQD---- 101
Cdd:cd03288 32 NLKPVLKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMVDIFDGKIVIDGIDISKLPLHTL----RSRLSIILQDpilf 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 102 -----YNLLDTLTVKENIL---LPLSITKLSKKEANRKFEEVAKELGiyelrdkypNEISGGQKQRTSAGRAFIHDPSII 173
Cdd:cd03288 108 sgsirFNLDPECKCTDDRLweaLEIAQLKNMVKSLPGGLDAVVTEGG---------ENFSVGQRQLFCLARAFVRKSSIL 178
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
8G4D_C 174 FADEPTGALDsKSASDLLNKLSqLNQKRNATIIMVTHDPVAASYCGRVIFIKDG 227
Cdd:cd03288 179 IMDEATASID-MATENILQKVV-MTAFADRTVVTIAHRVSTILDADLVLVLSRG 230
|
|
| PLN03130 |
PLN03130 |
ABC transporter C family member; Provisional |
30-183 |
1.52e-06 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 48.97 E-value: 1.52e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 30 VLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKekqLAEFRKQhLGFIFQDYNL----- 104
Cdd:PLN03130 1254 VLHGLSFEISPSEKVGIVGRTGAGKSSMLNALFRIVELERGRILIDGCDISKFG---LMDLRKV-LGIIPQAPVLfsgtv 1329
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 105 ---LDTLTVKENILLPLSITKLSKKEANRKfeevaKELGI-YELRDKYPNeISGGQKQRTSAGRAFIHDPSIIFADEPTG 180
Cdd:PLN03130 1330 rfnLDPFNEHNDADLWESLERAHLKDVIRR-----NSLGLdAEVSEAGEN-FSVGQRQLLSLARALLRRSKILVLDEATA 1403
|
...
8G4D_C 181 ALD 183
Cdd:PLN03130 1404 AVD 1406
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
38-229 |
1.57e-06 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 48.67 E-value: 1.57e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 38 IEKGEFVSIMGASGSGKTTLLNVLSSIDQVSH-GTIHING------NDMTAMKEK--QLAEFRKQHlgfifqdyNLLDTL 108
Cdd:TIGR02633 283 LRRGEILGVAGLVGAGRTELVQALFGAYPGKFeGNVFINGkpvdirNPAQAIRAGiaMVPEDRKRH--------GIVPIL 354
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 109 TVKENILLPL--SITKLSKKEANRKFEEVAKELGIYELRDKYPN----EISGGQKQRTSAGRAFIHDPSIIFADEPTGAL 182
Cdd:TIGR02633 355 GVGKNITLSVlkSFCFKMRIDAAAELQIIGSAIQRLKVKTASPFlpigRLSGGNQQKAVLAKMLLTNPRVLILDEPTRGV 434
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
8G4D_C 183 DSKSASDLLNKLSQLNQKRNATIIMVTHDPVAASYCGRVIFIKDGQM 229
Cdd:TIGR02633 435 DVGAKYEIYKLINQLAQEGVAIIVVSSELAEVLGLSDRVLVIGEGKL 481
|
|
| sufC |
PRK09580 |
cysteine desulfurase ATPase component; Reviewed |
28-237 |
1.63e-06 |
|
cysteine desulfurase ATPase component; Reviewed
Pssm-ID: 181965 [Multi-domain] Cd Length: 248 Bit Score: 47.86 E-value: 1.63e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 28 QEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSID--QVSHGTIHINGNDMTAMKEKQLAefrKQHLGFIFQdYNlL 105
Cdd:PRK09580 14 KAILRGLNLEVRPGEVHAIMGPNGSGKSTLSATLAGREdyEVTGGTVEFKGKDLLELSPEDRA---GEGIFMAFQ-YP-V 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 106 DTLTVKENILLPLSITKLSK---KEANRKF------EEVAKELGIYE-LRDKYPNE-ISGGQKQRTSAGRAFIHDPSIIF 174
Cdd:PRK09580 89 EIPGVSNQFFLQTALNAVRSyrgQEPLDRFdfqdlmEEKIALLKMPEdLLTRSVNVgFSGGEKKRNDILQMAVLEPELCI 168
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
8G4D_C 175 ADEPTGALDSKSASDLLNKLSQLNQKRNATIImVTH----------DPVAASYCGRVIFIKDGQMYTQLNKGG 237
Cdd:PRK09580 169 LDESDSGLDIDALKIVADGVNSLRDGKRSFII-VTHyqrildyikpDYVHVLYQGRIVKSGDFTLVKQLEEQG 240
|
|
| tagH |
PRK13545 |
teichoic acids export protein ATP-binding subunit; Provisional |
31-229 |
3.39e-06 |
|
teichoic acids export protein ATP-binding subunit; Provisional
Pssm-ID: 184130 [Multi-domain] Cd Length: 549 Bit Score: 47.58 E-value: 3.39e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 31 LKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNdmtamkekqlaefrkqhLGFIFQDYNLLDTLTV 110
Cdd:PRK13545 40 LNNISFEVPEGEIVGIIGLNGSGKSTLSNLIAGVTMPNKGTVDIKGS-----------------AALIAISSGLNGQLTG 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 111 KENILLPLSITKLSKKEANRKFEEVAKELGIYELRDKYPNEISGGQKQRTSAGRAFIHDPSIIFADEPTGALDSKSASDL 190
Cdd:PRK13545 103 IENIELKGLMMGLTKEKIKEIIPEIIEFADIGKFIYQPVKTYSSGMKSRLGFAISVHINPDILVIDEALSVGDQTFTKKC 182
|
170 180 190 200
....*....|....*....|....*....|....*....|
8G4D_C 191 LNKLSQLNQKrNATIIMVTHD-PVAASYCGRVIFIKDGQM 229
Cdd:PRK13545 183 LDKMNEFKEQ-GKTIFFISHSlSQVKSFCTKALWLHYGQV 221
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
29-211 |
9.54e-06 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 46.20 E-value: 9.54e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 29 EVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQ--------LAEFRKQHlGfIFQ 100
Cdd:PRK15439 277 EGFRNISLEVRAGEILGLAGVVGAGRTELAETLYGLRPARGGRIMLNGKEINALSTAQrlarglvyLPEDRQSS-G-LYL 354
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 101 DYNL---LDTLTVKENILLplsitkLSKKEANRKFEEVAKELGI-YELRDKYPNEISGGQKQRTSAGRAFIHDPSIIFAD 176
Cdd:PRK15439 355 DAPLawnVCALTHNRRGFW------IKPARENAVLERYRRALNIkFNHAEQAARTLSGGNQQKVLIAKCLEASPQLLIVD 428
|
170 180 190
....*....|....*....|....*....|....*
8G4D_C 177 EPTGALDSKSASDLLNKLSQLnQKRNATIIMVTHD 211
Cdd:PRK15439 429 EPTRGVDVSARNDIYQLIRSI-AAQNVAVLFISSD 462
|
|
| ABC_RNaseL_inhibitor |
cd03222 |
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ... |
151-228 |
1.06e-05 |
|
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213189 [Multi-domain] Cd Length: 177 Bit Score: 44.87 E-value: 1.06e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 151 EISGGQKQRTSAGRAFIHDPSIIFADEPTGALDSK---SASDLLNKLSQLNQKrnaTIIMVTHDPVAASYCGRVIFIKDG 227
Cdd:cd03222 71 DLSGGELQRVAIAAALLRNATFYLFDEPSAYLDIEqrlNAARAIRRLSEEGKK---TALVVEHDLAVLDYLSDRIHVFEG 147
|
.
8G4D_C 228 Q 228
Cdd:cd03222 148 E 148
|
|
| PLN03140 |
PLN03140 |
ABC transporter G family member; Provisional |
24-232 |
1.07e-05 |
|
ABC transporter G family member; Provisional
Pssm-ID: 215599 [Multi-domain] Cd Length: 1470 Bit Score: 46.38 E-value: 1.07e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 24 KLNKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLS-SID---QVShGTIHINGNdmtamkekQLAEF--RKQHlGF 97
Cdd:PLN03140 174 KKTKLTILKDASGIIKPSRMTLLLGPPSSGKTTLLLALAgKLDpslKVS-GEITYNGY--------RLNEFvpRKTS-AY 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 98 IFQDYNLLDTLTVKENilLPLS------------ITKLSKKEANRK-FEEVAKEL--------GI-------YELR---- 145
Cdd:PLN03140 244 ISQNDVHVGVMTVKET--LDFSarcqgvgtrydlLSELARREKDAGiFPEAEVDLfmkatameGVksslitdYTLKilgl 321
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 146 ---------DKYPNEISGGQKQRTSAGRAFIHDPSIIFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHDPVAAS 216
Cdd:PLN03140 322 dickdtivgDEMIRGISGGQKKRVTTGEMIVGPTKTLFMDEISTGLDSSTTYQIVKCLQQIVHLTEATVLMSLLQPAPET 401
|
250
....*....|....*...
8G4D_C 217 Y--CGRVIFIKDGQMYTQ 232
Cdd:PLN03140 402 FdlFDDIILLSEGQIVYQ 419
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
10-74 |
3.11e-05 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 44.72 E-value: 3.11e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
8G4D_C 10 VILEANKIRKSYGNKLnkqeVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHI 74
Cdd:PRK11819 323 KVIEAENLSKSFGDRL----LIDDLSFSLPPGGIVGIIGPNGAGKSTLFKMITGQEQPDSGTIKI 383
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
40-211 |
7.89e-05 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 43.45 E-value: 7.89e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 40 KGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDMTAMKEKQ--------LAEFRKQHlgfifqdyNLLDTLTVK 111
Cdd:PRK10762 277 KGEILGVSGLMGAGRTELMKVLYGALPRTSGYVTLDGHEVVTRSPQDglangivyISEDRKRD--------GLVLGMSVK 348
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 112 ENILLPlSITKLSKK--EANRKFEEVAKELGIYELRDKYPN------EISGGQKQRTSAGRAFIHDPSIIFADEPTGALD 183
Cdd:PRK10762 349 ENMSLT-ALRYFSRAggSLKHADEQQAVSDFIRLFNIKTPSmeqaigLLSGGNQQKVAIARGLMTRPKVLILDEPTRGVD 427
|
170 180 190
....*....|....*....|....*....|.
8G4D_C 184 ---SKSASDLLNKLsqlnQKRNATIIMVTHD 211
Cdd:PRK10762 428 vgaKKEIYQLINQF----KAEGLSIILVSSE 454
|
|
| GguA |
NF040905 |
sugar ABC transporter ATP-binding protein; |
30-183 |
9.47e-05 |
|
sugar ABC transporter ATP-binding protein;
Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 43.24 E-value: 9.47e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 30 VLKGIDIHIEKGEFVSIMGASGSGKTTLlnVLS----SIDQVSHGTIHING-----NDMTAMKEKQLA---EFRKqHLGF 97
Cdd:NF040905 275 VVDDVSLNVRRGEIVGIAGLMGAGRTEL--AMSvfgrSYGRNISGTVFKDGkevdvSTVSDAIDAGLAyvtEDRK-GYGL 351
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 98 ifqdyNLLDtlTVKENILLPlSITKLSKKEANRKFEE--VAKElgiY--ELRDKYPN------EISGGQKQRTSAGRAFI 167
Cdd:NF040905 352 -----NLID--DIKRNITLA-NLGKVSRRGVIDENEEikVAEE---YrkKMNIKTPSvfqkvgNLSGGNQQKVVLSKWLF 420
|
170
....*....|....*.
8G4D_C 168 HDPSIIFADEPTGALD 183
Cdd:NF040905 421 TDPDVLILDEPTRGID 436
|
|
| uvrA |
PRK00349 |
excinuclease ABC subunit UvrA; |
31-59 |
1.28e-04 |
|
excinuclease ABC subunit UvrA;
Pssm-ID: 234734 [Multi-domain] Cd Length: 943 Bit Score: 43.14 E-value: 1.28e-04
10 20
....*....|....*....|....*....
8G4D_C 31 LKGIDIHIEKGEFVSIMGASGSGKTTLLN 59
Cdd:PRK00349 625 LKNVDVEIPLGKFTCVTGVSGSGKSTLIN 653
|
|
| PLN03073 |
PLN03073 |
ABC transporter F family; Provisional |
41-210 |
1.53e-04 |
|
ABC transporter F family; Provisional
Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 42.92 E-value: 1.53e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 41 GEFVSIMGASGSGKTTLLN--VLSSID------QVSHGTIHINGNDMTAMK--------EKQLAEFRKQhlgfIFQDYNL 104
Cdd:PLN03073 203 GRHYGLVGRNGTGKTTFLRymAMHAIDgipkncQILHVEQEVVGDDTTALQcvlntdieRTQLLEEEAQ----LVAQQRE 278
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 105 LDTLTVKENILLPlSITKLSKKEANRKFEEVAKELgiyELRDKYPNE-----------------------ISGGQKQRTS 161
Cdd:PLN03073 279 LEFETETGKGKGA-NKDGVDKDAVSQRLEEIYKRL---ELIDAYTAEaraasilaglsftpemqvkatktFSGGWRMRIA 354
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
8G4D_C 162 AGRAFIHDPSIIFADEPTGALDSKSASDLLNKLSqlnqKRNATIIMVTH 210
Cdd:PLN03073 355 LARALFIEPDLLLLDEPTNHLDLHAVLWLETYLL----KWPKTFIVVSH 399
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
40-229 |
1.76e-04 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 42.22 E-value: 1.76e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 40 KGEFVSIMGASGSGKTTLLNVL-SSIDQVSHGTIHINGNDMT------AMKEK--QLAEFRKQHlgfifqdyNLLDTLTV 110
Cdd:PRK13549 287 RGEILGIAGLVGAGRTELVQCLfGAYPGRWEGEIFIDGKPVKirnpqqAIAQGiaMVPEDRKRD--------GIVPVMGV 358
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 111 KENILLPlSITKLSKKEA-NRKFEEVAKELGIYELRDKYPN------EISGGQKQRTSAGRAFIHDPSIIFADEPTGALD 183
Cdd:PRK13549 359 GKNITLA-ALDRFTGGSRiDDAAELKTILESIQRLKVKTASpelaiaRLSGGNQQKAVLAKCLLLNPKILILDEPTRGID 437
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
8G4D_C 184 SKSASDLLNKLSQLNQkRNATIIMVTHD-PVAASYCGRVIFIKDGQM 229
Cdd:PRK13549 438 VGAKYEIYKLINQLVQ-QGVAIIVISSElPEVLGLSDRVLVMHEGKL 483
|
|
| UvrA |
COG0178 |
Excinuclease UvrABC ATPase subunit [Replication, recombination and repair]; |
31-59 |
2.34e-04 |
|
Excinuclease UvrABC ATPase subunit [Replication, recombination and repair];
Pssm-ID: 439948 [Multi-domain] Cd Length: 941 Bit Score: 42.32 E-value: 2.34e-04
10 20
....*....|....*....|....*....
8G4D_C 31 LKGIDIHIEKGEFVSIMGASGSGKTTLLN 59
Cdd:COG0178 621 LKNVDVEIPLGVLTCVTGVSGSGKSTLVN 649
|
|
| ABC_UvrA_I |
cd03270 |
ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair ... |
31-212 |
3.92e-04 |
|
ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.
Pssm-ID: 213237 [Multi-domain] Cd Length: 226 Bit Score: 40.70 E-value: 3.92e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 31 LKGIDIHIEKGEFVSIMGASGSGKTTL-------------LNVLSS-----IDQVSHGTI-HINGNDMT-AMKEKQLAEF 90
Cdd:cd03270 11 LKNVDVDIPRNKLVVITGVSGSGKSSLafdtiyaegqrryVESLSAyarqfLGQMDKPDVdSIEGLSPAiAIDQKTTSRN 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 91 RKQHLGFIFQDYNLLDTLTVKENIllplsITKLskkeanrkfeEVAKELGIYELR-DKYPNEISGGQKQR----TSAGRA 165
Cdd:cd03270 91 PRSTVGTVTEIYDYLRLLFARVGI-----RERL----------GFLVDVGLGYLTlSRSAPTLSGGEAQRirlaTQIGSG 155
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
8G4D_C 166 FIhdpSIIFA-DEPTGALDSKSASDLLNKLSQLNQKRNaTIIMVTHDP 212
Cdd:cd03270 156 LT---GVLYVlDEPSIGLHPRDNDRLIETLKRLRDLGN-TVLVVEHDE 199
|
|
| uvra |
TIGR00630 |
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ... |
31-59 |
5.77e-04 |
|
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273184 [Multi-domain] Cd Length: 925 Bit Score: 41.15 E-value: 5.77e-04
10 20
....*....|....*....|....*....
8G4D_C 31 LKGIDIHIEKGEFVSIMGASGSGKTTLLN 59
Cdd:TIGR00630 624 LKNITVSIPLGLFTCITGVSGSGKSTLIN 652
|
|
| PRK10636 |
PRK10636 |
putative ABC transporter ATP-binding protein; Provisional |
11-211 |
6.01e-04 |
|
putative ABC transporter ATP-binding protein; Provisional
Pssm-ID: 236729 [Multi-domain] Cd Length: 638 Bit Score: 40.92 E-value: 6.01e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 11 ILEANKIRKSYGNKLnkqeVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSsidqvshGTIHINGNDMTAMKEKQLAEF 90
Cdd:PRK10636 312 LLKMEKVSAGYGDRI----ILDSIKLNLVPGSRIGLLGRNGAGKSTLIKLLA-------GELAPVSGEIGLAKGIKLGYF 380
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 91 RKQHLGFIFQDYNLLDTLtvkenillplsiTKLSKKEANRKFEEVakeLGIYELR-DKYPNE---ISGGQKQRTSAGRAF 166
Cdd:PRK10636 381 AQHQLEFLRADESPLQHL------------ARLAPQELEQKLRDY---LGGFGFQgDKVTEEtrrFSGGEKARLVLALIV 445
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
8G4D_C 167 IHDPSIIFADEPTGALDsksaSDLLNKLSQLNQKRNATIIMVTHD 211
Cdd:PRK10636 446 WQRPNLLLLDEPTNHLD----LDMRQALTEALIDFEGALVVVSHD 486
|
|
| PRK13546 |
PRK13546 |
teichoic acids export ABC transporter ATP-binding subunit TagH; |
22-249 |
6.38e-04 |
|
teichoic acids export ABC transporter ATP-binding subunit TagH;
Pssm-ID: 184131 [Multi-domain] Cd Length: 264 Bit Score: 40.18 E-value: 6.38e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 22 GNKLNKQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNdmtamkekqlaefrkqhLGFIFQD 101
Cdd:PRK13546 31 KHKNKTFFALDDISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTVGKVDRNGE-----------------VSVIAIS 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 102 YNLLDTLTVKENILLPLSITKLSKKEANRKFEEVAK--ELG--IYELRDKYpneiSGGQKQRTSAGRAFIHDPSIIFADE 177
Cdd:PRK13546 94 AGLSGQLTGIENIEFKMLCMGFKRKEIKAMTPKIIEfsELGefIYQPVKKY----SSGMRAKLGFSINITVNPDILVIDE 169
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
8G4D_C 178 PTGALDSKSASDLLNKLSQLnQKRNATIIMVTHD-PVAASYCGRVIFIKDGQM--YTQLNKGGQDRQTFFQDIMK 249
Cdd:PRK13546 170 ALSVGDQTFAQKCLDKIYEF-KEQNKTIFFVSHNlGQVRQFCTKIAWIEGGKLkdYGELDDVLPKYEAFLNDFKK 243
|
|
| PRK15064 |
PRK15064 |
ABC transporter ATP-binding protein; Provisional |
48-211 |
6.74e-04 |
|
ABC transporter ATP-binding protein; Provisional
Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 40.65 E-value: 6.74e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 48 GASGSGKTTLLNVLSSIDQVSHGTIHINGNDmtamkekQLAEFRKQHlgFIFQDYNLLDTLTVKEnillplsiTKL--SK 125
Cdd:PRK15064 34 GANGCGKSTFMKILGGDLEPSAGNVSLDPNE-------RLGKLRQDQ--FAFEEFTVLDTVIMGH--------TELweVK 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 126 KEANR--------------------KFEEV--------AKEL----GI-YELRDKYPNEISGGQKQRTSAGRAFIHDPSI 172
Cdd:PRK15064 97 QERDRiyalpemseedgmkvadlevKFAEMdgytaearAGELllgvGIpEEQHYGLMSEVAPGWKLRVLLAQALFSNPDI 176
|
170 180 190
....*....|....*....|....*....|....*....
8G4D_C 173 IFADEPTGALDSKSASDLLNKLSQlnqkRNATIIMVTHD 211
Cdd:PRK15064 177 LLLDEPTNNLDINTIRWLEDVLNE----RNSTMIIISHD 211
|
|
| PLN03073 |
PLN03073 |
ABC transporter F family; Provisional |
30-211 |
9.00e-04 |
|
ABC transporter F family; Provisional
Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 40.23 E-value: 9.00e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 30 VLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGndmtamkEKQLAEFRKQHLgfifqdynllDTLT 109
Cdd:PLN03073 524 LFKNLNFGIDLDSRIAMVGPNGIGKSTILKLISGELQPSSGTVFRSA-------KVRMAVFSQHHV----------DGLD 586
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 110 VKENILLPLSitKLSKKEANRKFEEVAKELGI---YELRDKYpnEISGGQKQRTSAGRAFIHDPSIIFADEPTGALDSKS 186
Cdd:PLN03073 587 LSSNPLLYMM--RCFPGVPEQKLRAHLGSFGVtgnLALQPMY--TLSGGQKSRVAFAKITFKKPHILLLDEPSNHLDLDA 662
|
170 180
....*....|....*....|....*
8G4D_C 187 ASDLLNKLSQLnqkrNATIIMVTHD 211
Cdd:PLN03073 663 VEALIQGLVLF----QGGVLMVSHD 683
|
|
| ABC_Class2 |
cd03227 |
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ... |
31-212 |
1.03e-03 |
|
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.
Pssm-ID: 213194 [Multi-domain] Cd Length: 162 Bit Score: 38.88 E-value: 1.03e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 31 LKGIDIHIEKGEFVSIMGASGSGKTTLlnvlssIDQVShgtihingndmtamkekqLAEFRKQHLGfifqdynlldtltv 110
Cdd:cd03227 11 FVPNDVTFGEGSLTIITGPNGSGKSTI------LDAIG------------------LALGGAQSAT-------------- 52
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 111 kenillplsitkLSKKEANRKFEEVAKELGIYELRDKypneISGGQKQRTS-----AGRAFIHDPSIIFaDEPTGALDSK 185
Cdd:cd03227 53 ------------RRRSGVKAGCIVAAVSAELIFTRLQ----LSGGEKELSAlalilALASLKPRPLYIL-DEIDRGLDPR 115
|
170 180
....*....|....*....|....*..
8G4D_C 186 SASDLLNKLSQLNQKrNATIIMVTHDP 212
Cdd:cd03227 116 DGQALAEAILEHLVK-GAQVIVITHLP 141
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
27-229 |
1.38e-03 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 39.71 E-value: 1.38e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 27 KQEVLKGIDIHIEKGEFVSIMGASGSGKTTLLNVLSSIDQVSHGTIHINGNDM---TAMKEKQ-----LAEFRKQHLGFI 98
Cdd:PRK10982 260 RQPSIRDVSFDLHKGEILGIAGLVGAKRTDIVETLFGIREKSAGTITLHGKKInnhNANEAINhgfalVTEERRSTGIYA 339
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 99 FQDYNLLDTLTVKENILLPLSITKLSKKEANRKFEevakelgIYELRDKYPNE------ISGGQKQRTSAGRAFIHDPSI 172
Cdd:PRK10982 340 YLDIGFNSLISNIRNYKNKVGLLDNSRMKSDTQWV-------IDSMRVKTPGHrtqigsLSGGNQQKVIIGRWLLTQPEI 412
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
8G4D_C 173 IFADEPTGALDSKSASDLLNKLSQLNQKRNATIIMVTHDPVAASYCGRVIFIKDGQM 229
Cdd:PRK10982 413 LMLDEPTRGIDVGAKFEIYQLIAELAKKDKGIIIISSEMPELLGITDRILVMSNGLV 469
|
|
| UvrA |
COG0178 |
Excinuclease UvrABC ATPase subunit [Replication, recombination and repair]; |
31-57 |
1.63e-03 |
|
Excinuclease UvrABC ATPase subunit [Replication, recombination and repair];
Pssm-ID: 439948 [Multi-domain] Cd Length: 941 Bit Score: 39.62 E-value: 1.63e-03
10 20
....*....|....*....|....*..
8G4D_C 31 LKGIDIHIEKGEFVSIMGASGSGKTTL 57
Cdd:COG0178 16 LKNIDVDIPRNKLVVITGLSGSGKSSL 42
|
|
| AAA_28 |
pfam13521 |
AAA domain; |
43-108 |
2.04e-03 |
|
AAA domain;
Pssm-ID: 433278 [Multi-domain] Cd Length: 164 Bit Score: 38.01 E-value: 2.04e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 43 FVSIMGASGSGKTTLLNVLSSI---------------DQVSHGTIHIN-GNDMTAMKEKQLAEFRKQHL-----GFIFQD 101
Cdd:pfam13521 1 RIVITGGPSTGKTTLAEALAARfgypvvpeaareileELGADGGDALPwVEDLLAFARGVLEAQLEDEAaaaanDLLFFD 80
|
....*..
8G4D_C 102 YNLLDTL 108
Cdd:pfam13521 81 RGPLDTL 87
|
|
| ABC_Rad50 |
cd03240 |
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ... |
153-225 |
3.44e-03 |
|
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.
Pssm-ID: 213207 [Multi-domain] Cd Length: 204 Bit Score: 37.59 E-value: 3.44e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8G4D_C 153 SGGQKQ------RTSAGRAFIHDPSIIFADEPTGALDSKSASD-LLNKLSQLNQKRNATIIMVTHDPVAASYCGRVIFIK 225
Cdd:cd03240 117 SGGEKVlasliiRLALAETFGSNCGILALDEPTTNLDEENIEEsLAEIIEERKSQKNFQLIVITHDEELVDAADHIYRVE 196
|
|
| uvra |
TIGR00630 |
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ... |
31-57 |
4.63e-03 |
|
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273184 [Multi-domain] Cd Length: 925 Bit Score: 38.07 E-value: 4.63e-03
10 20
....*....|....*....|....*..
8G4D_C 31 LKGIDIHIEKGEFVSIMGASGSGKTTL 57
Cdd:TIGR00630 12 LKNIDVEIPRDKLVVITGLSGSGKSSL 38
|
|
| CpaF |
COG4962 |
Pilus assembly protein, ATPase of CpaF family [Intracellular trafficking, secretion, and ... |
48-63 |
5.42e-03 |
|
Pilus assembly protein, ATPase of CpaF family [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];
Pssm-ID: 443988 [Multi-domain] Cd Length: 386 Bit Score: 37.84 E-value: 5.42e-03
10
....*....|....*.
8G4D_C 48 GASGSGKTTLLNVLSS 63
Cdd:COG4962 189 GGTGSGKTTLLNALSG 204
|
|
| |
