NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|160395523|sp|A3KGW5|]
View 

RecName: Full=Inactive glycosyltransferase 25 family member 3; AltName: Full=Cerebral endothelial cell adhesion molecule; Flags: Precursor

Protein Classification

glycosyltransferase family 2 protein; glycosyltransferase family 25 protein( domain architecture ID 10091613)

glycosyltransferase family 2 protein catalyzes the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds| glycosyltransferase family 25 protein may be involved in lipopolysaccharide (LPS) biosynthesis, facilitating the transfer of one of a variety of sugars onto a growing LPS chain, such as lacto-N-neotetraose biosynthesis glycosyltransferase LgtB, which adds the second galactose to the lacto-N-tetraose chain in lipooligosaccharide (LOS)

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
COG3306 COG3306
Glycosyltransferase involved in LPS biosynthesis, GR25 family [Cell wall/membrane/envelope ...
319-531 2.83e-43

Glycosyltransferase involved in LPS biosynthesis, GR25 family [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442535 [Multi-domain]  Cd Length: 238  Bit Score: 154.77  E-value: 2.83e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160395523 319 VFVISLARRPQRRARMLSSLWEMEISAQVVDAVDGRTLNSSILKHLGvdllPGYQDPYSGHTLTKGEVGCFLSHYSIWEE 398
Cdd:COG3306    3 IFVINLDRSTERREHIEAQLARLGLDFEFFDAVDGRDLSEEELARYD----RAKALRRYGRPLTPGEIGCFLSHRKAWQK 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160395523 399 VVARGLARVVVFEDDVRFKDNFRRRLERLMEdvliQKLSWDLIYLGRKQvnpeEEVAVEGLPGLVVAGYS--------YW 470
Cdd:COG3306   79 IVESGLPYALILEDDVILSPDFAEVLEALAW----LPADWDIVKLETSK----RKVFLGRRKIKKLGGYRlvrpysppLG 150
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 160395523 471 TLAYTLSLAGARKLLA-SQPLHRmlPVDEFlpvMFDrhpndqykayFWPRDLQAFSARPLLA 531
Cdd:COG3306  151 TAGYLISRKAAKKLLAlLEPIDR--PVDDF---LFR----------FWLHGLRVYQVRPALV 197
BcsA super family cl43359
Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1, ...
18-156 1.54e-04

Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase [Cell motility];


The actual alignment was detected with superfamily member COG1215:

Pssm-ID: 440828 [Multi-domain]  Cd Length: 303  Bit Score: 43.96  E-value: 1.54e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160395523  18 RAASVTEPTLPTVVLAILARNAEHSLPHYLGALERLDYPRARLALWCATDHNMDNTTGMLREWLAAVGRdyATVVWKPEE 97
Cdd:COG1215   19 ARRRRAPADLPRVSVIIPAYNEEAVIEETLRSLLAQDYPKEKLEVIVVDDGSTDETAEIARELAAEYPR--VRVIERPEN 96
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 160395523  98 earsypdeqGPKHWTkerhqflmelRQEALAFARdwgADYILFADTDNILTNNQTLKLL 156
Cdd:COG1215   97 ---------GGKAAA----------LNAGLKAAR---GDIVVFLDADTVLDPDWLRRLV 133
 
Name Accession Description Interval E-value
COG3306 COG3306
Glycosyltransferase involved in LPS biosynthesis, GR25 family [Cell wall/membrane/envelope ...
319-531 2.83e-43

Glycosyltransferase involved in LPS biosynthesis, GR25 family [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442535 [Multi-domain]  Cd Length: 238  Bit Score: 154.77  E-value: 2.83e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160395523 319 VFVISLARRPQRRARMLSSLWEMEISAQVVDAVDGRTLNSSILKHLGvdllPGYQDPYSGHTLTKGEVGCFLSHYSIWEE 398
Cdd:COG3306    3 IFVINLDRSTERREHIEAQLARLGLDFEFFDAVDGRDLSEEELARYD----RAKALRRYGRPLTPGEIGCFLSHRKAWQK 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160395523 399 VVARGLARVVVFEDDVRFKDNFRRRLERLMEdvliQKLSWDLIYLGRKQvnpeEEVAVEGLPGLVVAGYS--------YW 470
Cdd:COG3306   79 IVESGLPYALILEDDVILSPDFAEVLEALAW----LPADWDIVKLETSK----RKVFLGRRKIKKLGGYRlvrpysppLG 150
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 160395523 471 TLAYTLSLAGARKLLA-SQPLHRmlPVDEFlpvMFDrhpndqykayFWPRDLQAFSARPLLA 531
Cdd:COG3306  151 TAGYLISRKAAKKLLAlLEPIDR--PVDDF---LFR----------FWLHGLRVYQVRPALV 197
Glyco_transf_25 cd06532
Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of ...
318-500 7.59e-38

Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of Neisseria gonorrhoeae and Lic2A of Haemophilus influenzae. M. catarrhalis Lgt2 catalyzes the addition of galactose (Gal) to the growing chain of LOS on the cell surface. N. gonorrhoeae LgtB and LgtE link Gal-beta(1,4) to GlcNAc (N-acetylglucosamine) and Glc (glucose), respectively. The genes encoding LgtB and LgtE are two genes of a five gene locus involved in the synthesis of gonococcal LOS. LgtE is believed to perform the first step in LOS biosynthesis.


Pssm-ID: 133474  Cd Length: 128  Bit Score: 136.19  E-value: 7.59e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160395523 318 EVFVISLARRPQRRARMLSSLWEMEISAQVVDAVDGRTLNSSILKHLGVDllpgYQDPYSGHTLTKGEVGCFLSHYSIWE 397
Cdd:cd06532    1 KIFVINLDRSTDRRERMEAQLAALGLDFEFFDAVDGKDLSEEELAALYDA----LFLPRYGRPLTPGEIGCFLSHYKLWQ 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160395523 398 EVVARGLARVVVFEDDVRFKDNfrrrlerlmedvliqklswdliylgrkqvnpeeevaveglpglvvagysyWTLAYTLS 477
Cdd:cd06532   77 KIVESNLEYALILEDDAILDPD--------------------------------------------------GTAGYLVS 106
                        170       180
                 ....*....|....*....|...
gi 160395523 478 LAGARKLLASQPLHRMlPVDEFL 500
Cdd:cd06532  107 RKGAKKLLAALEPIDL-PVDVFL 128
Glyco_transf_25 pfam01755
Glycosyltransferase family 25 (LPS biosynthesis protein); Members of this family belong to ...
316-500 8.53e-35

Glycosyltransferase family 25 (LPS biosynthesis protein); Members of this family belong to Glycosyltransferase family 25 This is a family of glycosyltransferases involved in lipopolysaccharide (LPS) biosynthesis. These enzymes catalyze the transfer of various sugars onto the growing LPS chain during its biosynthesis.


Pssm-ID: 366794  Cd Length: 200  Bit Score: 130.25  E-value: 8.53e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160395523  316 FDEVFVISLARRPQRRARMLSSLWEMEISAQVVDAVDGRTLNSSILKHlgvDLLPGYQDPYSGHTLTKGEVGCFLSHYSI 395
Cdd:pfam01755   1 MIKIYVISLKRATERREHIQKEFGKLNIPFQFFDAIDGKELPNHLLFK---LYNFLLRSKYAGRPLTLGEIGCFLSHYSL 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160395523  396 WEEVVARGLARVVVFEDDVRFKDNFRRRLERLMEDvliqKLSWDLIYLGRKQVNP--EEEVAVEGLPGLVVAGYSY---- 469
Cdd:pfam01755  78 WQKCVELNLEYIIILEDDVILSENFKAILQFLLKE----INELEFLRLGEWLKTRfdPNDKFIVRLETFLMDSKKFkrtp 153
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 160395523  470 -----------------WTLAYTLSLAGARKLL-ASQPLhrMLPVDEFL 500
Cdd:pfam01755 154 iadygnrafyllksghaGTAGYLITPKAAKKLLkYSKNW--PLPVDDLM 200
BcsA COG1215
Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1, ...
18-156 1.54e-04

Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase [Cell motility];


Pssm-ID: 440828 [Multi-domain]  Cd Length: 303  Bit Score: 43.96  E-value: 1.54e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160395523  18 RAASVTEPTLPTVVLAILARNAEHSLPHYLGALERLDYPRARLALWCATDHNMDNTTGMLREWLAAVGRdyATVVWKPEE 97
Cdd:COG1215   19 ARRRRAPADLPRVSVIIPAYNEEAVIEETLRSLLAQDYPKEKLEVIVVDDGSTDETAEIARELAAEYPR--VRVIERPEN 96
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 160395523  98 earsypdeqGPKHWTkerhqflmelRQEALAFARdwgADYILFADTDNILTNNQTLKLL 156
Cdd:COG1215   97 ---------GGKAAA----------LNAGLKAAR---GDIVVFLDADTVLDPDWLRRLV 133
Glyco_tranf_GTA_type cd00761
Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a ...
34-157 2.33e-04

Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities.


Pssm-ID: 132997 [Multi-domain]  Cd Length: 156  Bit Score: 41.72  E-value: 2.33e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160395523  34 ILARNAEHSLPHYLGALERLDYPRARlaLWCATDHNMDNTTGMLREWLAAVGRdyatvvwkpeeearsypdeqgPKHWTK 113
Cdd:cd00761    3 IPAYNEEPYLERCLESLLAQTYPNFE--VIVVDDGSTDGTLEILEEYAKKDPR---------------------VIRVIN 59
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 160395523 114 ERHQFLMELRQEALAFARdwgADYILFADTDNILTNNQTLKLLI 157
Cdd:cd00761   60 EENQGLAAARNAGLKAAR---GEYILFLDADDLLLPDWLERLVA 100
 
Name Accession Description Interval E-value
COG3306 COG3306
Glycosyltransferase involved in LPS biosynthesis, GR25 family [Cell wall/membrane/envelope ...
319-531 2.83e-43

Glycosyltransferase involved in LPS biosynthesis, GR25 family [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442535 [Multi-domain]  Cd Length: 238  Bit Score: 154.77  E-value: 2.83e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160395523 319 VFVISLARRPQRRARMLSSLWEMEISAQVVDAVDGRTLNSSILKHLGvdllPGYQDPYSGHTLTKGEVGCFLSHYSIWEE 398
Cdd:COG3306    3 IFVINLDRSTERREHIEAQLARLGLDFEFFDAVDGRDLSEEELARYD----RAKALRRYGRPLTPGEIGCFLSHRKAWQK 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160395523 399 VVARGLARVVVFEDDVRFKDNFRRRLERLMEdvliQKLSWDLIYLGRKQvnpeEEVAVEGLPGLVVAGYS--------YW 470
Cdd:COG3306   79 IVESGLPYALILEDDVILSPDFAEVLEALAW----LPADWDIVKLETSK----RKVFLGRRKIKKLGGYRlvrpysppLG 150
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 160395523 471 TLAYTLSLAGARKLLA-SQPLHRmlPVDEFlpvMFDrhpndqykayFWPRDLQAFSARPLLA 531
Cdd:COG3306  151 TAGYLISRKAAKKLLAlLEPIDR--PVDDF---LFR----------FWLHGLRVYQVRPALV 197
Glyco_transf_25 cd06532
Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of ...
318-500 7.59e-38

Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of Neisseria gonorrhoeae and Lic2A of Haemophilus influenzae. M. catarrhalis Lgt2 catalyzes the addition of galactose (Gal) to the growing chain of LOS on the cell surface. N. gonorrhoeae LgtB and LgtE link Gal-beta(1,4) to GlcNAc (N-acetylglucosamine) and Glc (glucose), respectively. The genes encoding LgtB and LgtE are two genes of a five gene locus involved in the synthesis of gonococcal LOS. LgtE is believed to perform the first step in LOS biosynthesis.


Pssm-ID: 133474  Cd Length: 128  Bit Score: 136.19  E-value: 7.59e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160395523 318 EVFVISLARRPQRRARMLSSLWEMEISAQVVDAVDGRTLNSSILKHLGVDllpgYQDPYSGHTLTKGEVGCFLSHYSIWE 397
Cdd:cd06532    1 KIFVINLDRSTDRRERMEAQLAALGLDFEFFDAVDGKDLSEEELAALYDA----LFLPRYGRPLTPGEIGCFLSHYKLWQ 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160395523 398 EVVARGLARVVVFEDDVRFKDNfrrrlerlmedvliqklswdliylgrkqvnpeeevaveglpglvvagysyWTLAYTLS 477
Cdd:cd06532   77 KIVESNLEYALILEDDAILDPD--------------------------------------------------GTAGYLVS 106
                        170       180
                 ....*....|....*....|...
gi 160395523 478 LAGARKLLASQPLHRMlPVDEFL 500
Cdd:cd06532  107 RKGAKKLLAALEPIDL-PVDVFL 128
Glyco_transf_25 pfam01755
Glycosyltransferase family 25 (LPS biosynthesis protein); Members of this family belong to ...
316-500 8.53e-35

Glycosyltransferase family 25 (LPS biosynthesis protein); Members of this family belong to Glycosyltransferase family 25 This is a family of glycosyltransferases involved in lipopolysaccharide (LPS) biosynthesis. These enzymes catalyze the transfer of various sugars onto the growing LPS chain during its biosynthesis.


Pssm-ID: 366794  Cd Length: 200  Bit Score: 130.25  E-value: 8.53e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160395523  316 FDEVFVISLARRPQRRARMLSSLWEMEISAQVVDAVDGRTLNSSILKHlgvDLLPGYQDPYSGHTLTKGEVGCFLSHYSI 395
Cdd:pfam01755   1 MIKIYVISLKRATERREHIQKEFGKLNIPFQFFDAIDGKELPNHLLFK---LYNFLLRSKYAGRPLTLGEIGCFLSHYSL 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160395523  396 WEEVVARGLARVVVFEDDVRFKDNFRRRLERLMEDvliqKLSWDLIYLGRKQVNP--EEEVAVEGLPGLVVAGYSY---- 469
Cdd:pfam01755  78 WQKCVELNLEYIIILEDDVILSENFKAILQFLLKE----INELEFLRLGEWLKTRfdPNDKFIVRLETFLMDSKKFkrtp 153
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 160395523  470 -----------------WTLAYTLSLAGARKLL-ASQPLhrMLPVDEFL 500
Cdd:pfam01755 154 iadygnrafyllksghaGTAGYLITPKAAKKLLkYSKNW--PLPVDDLM 200
BcsA COG1215
Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1, ...
18-156 1.54e-04

Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase [Cell motility];


Pssm-ID: 440828 [Multi-domain]  Cd Length: 303  Bit Score: 43.96  E-value: 1.54e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160395523  18 RAASVTEPTLPTVVLAILARNAEHSLPHYLGALERLDYPRARLALWCATDHNMDNTTGMLREWLAAVGRdyATVVWKPEE 97
Cdd:COG1215   19 ARRRRAPADLPRVSVIIPAYNEEAVIEETLRSLLAQDYPKEKLEVIVVDDGSTDETAEIARELAAEYPR--VRVIERPEN 96
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 160395523  98 earsypdeqGPKHWTkerhqflmelRQEALAFARdwgADYILFADTDNILTNNQTLKLL 156
Cdd:COG1215   97 ---------GGKAAA----------LNAGLKAAR---GDIVVFLDADTVLDPDWLRRLV 133
Glyco_tranf_GTA_type cd00761
Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a ...
34-157 2.33e-04

Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities.


Pssm-ID: 132997 [Multi-domain]  Cd Length: 156  Bit Score: 41.72  E-value: 2.33e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160395523  34 ILARNAEHSLPHYLGALERLDYPRARlaLWCATDHNMDNTTGMLREWLAAVGRdyatvvwkpeeearsypdeqgPKHWTK 113
Cdd:cd00761    3 IPAYNEEPYLERCLESLLAQTYPNFE--VIVVDDGSTDGTLEILEEYAKKDPR---------------------VIRVIN 59
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 160395523 114 ERHQFLMELRQEALAFARdwgADYILFADTDNILTNNQTLKLLI 157
Cdd:cd00761   60 EENQGLAAARNAGLKAAR---GEYILFLDADDLLLPDWLERLVA 100
GT_2_like_e cd04192
Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse ...
34-83 8.50e-04

Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.


Pssm-ID: 133035 [Multi-domain]  Cd Length: 229  Bit Score: 41.12  E-value: 8.50e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 160395523  34 ILARNAEHSLPHYLGALERLDYPRARLALWCATDHNMDNTTgMLREWLAA 83
Cdd:cd04192    3 IAARNEAENLPRLLQSLSALDYPKEKFEVILVDDHSTDGTV-QILEFAAA 51
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH