|
Name |
Accession |
Description |
Interval |
E-value |
| pgi |
PRK00179 |
glucose-6-phosphate isomerase; Reviewed |
7-556 |
0e+00 |
|
glucose-6-phosphate isomerase; Reviewed
Pssm-ID: 234679 Cd Length: 548 Bit Score: 1047.07 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 7 PLNQEAAFQKLQEYYDsKGKDLNIKDLFVKDSKRFSKYSLRLhtqndGEILLDYSKNRINDEVWDLLLTLAKVRRVNAAR 86
Cdd:PRK00179 4 NLTQTPAWQALQAHAD-EIKDVHLRDLFAADPDRFERFSLTA-----GGLLLDYSKNRITDETLALLLDLAREAGLEGAR 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 87 DAMFSGQHINITENRAVLHTALRNRGTDPVLVDDKDVMPDVRAELAHMKEFTNMVISGVWRGCTGKQITDVVNIGIGGSD 166
Cdd:PRK00179 78 DAMFAGEKINTTEDRAVLHTALRNPSNTPILVDGQDVMPEVHAVLARMKAFAEAVRSGEWKGYTGKAITDVVNIGIGGSD 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 167 LGPLMVTEALKPYGK-GLHSHFVSNIDGTHLAEVLKKVNYETTLFIVASKTFTTQETITNATSAKTWLLEHSKEPESVAK 245
Cdd:PRK00179 158 LGPVMVTEALRPYADpGLRVHFVSNVDGAHLAETLKKLDPETTLFIVASKTFTTQETLTNAHSARDWFLAAGGDEAAVAK 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 246 HFVALSTNKEKVTEFGIDSTNMFGFWDWVGGRYSLWSAIGLSICLSIGFENFEQLLDGAHFMDNHFKTTPFEKNAPVILA 325
Cdd:PRK00179 238 HFVAVSTNAEAVAEFGIDPDNMFGFWDWVGGRYSLWSAIGLSIALAIGPDNFEELLAGAHAMDEHFRTAPLEKNLPVLLA 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 326 LLGVWYSNFFKAETHALLPYDQYLHRFAAYFQQGDMESNGKFVSKSGKPVKYSTGPIVWGEPGTNGQHAFYQLIHQGTRL 405
Cdd:PRK00179 318 LIGVWYRNFFGAQSHAVLPYDQYLHRFPAYLQQLEMESNGKSVDRDGTPVDYQTGPIIWGEPGTNGQHAFFQLLHQGTKL 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 406 IPCDFIAPAQTHNPIAGgkHHKILLSNFLAQTEALMAGKTVDEARTELSKAGLCGNELDNLLPHKVFVGNRPTNSIVVKK 485
Cdd:PRK00179 398 VPADFIAPAQPHNPLGD--HHDLLLANCFAQTEALMFGKTAEEVRAELRAKGLDEAEAEELAPHKVFPGNRPSTTILLDR 475
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 706912 486 VSPFTLGALIALYEHKIFVQGIIWDINSFDQWGVELGKQLAKAIEPELDHCNEVSTHDSSTNGLINFIKAN 556
Cdd:PRK00179 476 LTPFTLGALIALYEHKVFVQGVIWGINSFDQWGVELGKQLAKRILPELEGDSEASAHDSSTNGLINRYRAW 546
|
|
| PGI |
pfam00342 |
Phosphoglucose isomerase; Phosphoglucose isomerase catalyzes the interconversion of ... |
59-550 |
0e+00 |
|
Phosphoglucose isomerase; Phosphoglucose isomerase catalyzes the interconversion of glucose-6-phosphate and fructose-6-phosphate.
Pssm-ID: 395271 Cd Length: 487 Bit Score: 866.40 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 59 DYSKNRINDEVWDLLLTLAKVRRVNAARDAMFSGQHINITENRAVLHTALRNRGTDPVLVDDKDVMPDVRAELAHMKEFT 138
Cdd:pfam00342 1 DYSKNHINDEILTALVKLAEERGVDAAREAMFNGEKINSTENRAVLHVALRNRSNTPIYVDGKDVMPEVNAVLAKMKSFS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 139 NMVISGVWRGCTGKQITDVVNIGIGGSDLGPLMVTEALKPY-GKGLHSHFVSNIDGTHLAEVLKKVNYETTLFIVASKTF 217
Cdd:pfam00342 81 ERVRSGEWKGYTGKAITDVVNIGIGGSDLGPVMVTEALKPYsGRDLDVHFVSNVDGTHIAEVLKKLNPETTLFIVASKTF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 218 TTQETITNATSAKTWLLEHSKEPESVAKHFVALSTNKEKVTEFGIDSTNMFGFWDWVGGRYSLWSAIGLSICLSIGFENF 297
Cdd:pfam00342 161 TTAETMTNAESAKEWLLKALKDDSAVAKHFIALSTNAEKVEEFGIDTKNMFEFWDWVGGRYSLWSAIGLPIALSIGFENF 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 298 EQLLDGAHFMDNHFKTTPFEKNAPVILALLGVWYSNFFKAETHALLPYDQYLHRFAAYFQQGDMESNGKFVSKSGKPVKY 377
Cdd:pfam00342 241 QQLLEGAHAMDKHFLSAPPEKNIPVLLALLGVWYNNFFGAQTHAILPYDQYLHRFPAYLQQLDMESNGKYVTRDGVLVDH 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 378 STGPIVWGEPGTNGQHAFYQLIHQGTRLIPCDFIAPAQTHNPIAgGKHHKILLSNFLAQTEALMAGKTVDEARTELSKAg 457
Cdd:pfam00342 321 QTGPIIFGEPGTNGQHAFYQLIHQGTRLIPCDFIGAVQSQNPEN-GDHHKILLSNFFAQTEALMVGKSPEEVRKELAAA- 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 458 lcgnELDNLLPHKVFVGNRPTNSIVVKKVSPFTLGALIALYEHKIFVQGIIWDINSFDQWGVELGKQLAKAIEPELDHCN 537
Cdd:pfam00342 399 ----DVEHLIPHKTFTGNRPSNSILVQKLTPATLGALIAMYEHKIFVQGAIWGINSFDQWGVELGKVLAKSILPELENSN 474
|
490
....*....|...
gi 706912 538 EVSTHDSSTNGLI 550
Cdd:pfam00342 475 KVSSHDSSTNGLI 487
|
|
| Pgi |
COG0166 |
Glucose-6-phosphate isomerase [Carbohydrate transport and metabolism]; Glucose-6-phosphate ... |
36-555 |
0e+00 |
|
Glucose-6-phosphate isomerase [Carbohydrate transport and metabolism]; Glucose-6-phosphate isomerase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439936 Cd Length: 484 Bit Score: 765.45 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 36 KDSKRFSKYSLRLhtqndGEILLDYSKNRINDEVWDLLLTLAKVRrvnAARDAMFSGQHINITENRAVLHTALRNRGTDp 115
Cdd:COG0166 8 QHLRRFERFSLEA-----AGLLLDYSKNRITDETLELLLELAEEE---EAREALFAGEKINPTEGRAVLHGALRLPEAG- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 116 vlvddKDVMPDVRAELAHMKEFTNMVIsgvwrgcTGKQITDVVNIGIGGSDLGPLMVTEALKPYGK-GLHSHFVSNIDGT 194
Cdd:COG0166 79 -----EDVMPEVREELARIKAFAEKVR-------TGKRITDVVNIGIGGSDLGPRAVIEALKPYFRdGPRVHFVSNVDPD 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 195 HLAEVLKKVNYETTLFIVASKTFTTQETITNATSAKTWLLEHSKEpeSVAKHFVALSTNKEKVTEFGIDS-TNMFGFWDW 273
Cdd:COG0166 147 YLAELLAGLDPETTLFIVISKSGTTQETLTNARVAREWLEKAGGE--DAAKHFVAVTDNAGALRAFGIDEgYNTFPFPDW 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 274 VGGRYSLWSAIGLSICLSIGFEnFEQLLDGAHFMDNHFKTTPFEKNAPVILALLGVWYSNFFKAETHALLPYDQYLHRFA 353
Cdd:COG0166 225 VGGRYSVLSAVGLLPAAAIGID-FEELLAGAHAMDEHFRTAPLEENPPVLLALLGIWYRNFKGAETEAVLPYDQRLERFP 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 354 AYFQQGDMESNGKFVSKSGKPVKYSTGPIvwGEPGTNGQHAFYQLIHQGTRLIPCDFIAPAQTHNPIAGgkhhkILLSNF 433
Cdd:COG0166 304 AWLQQLWMESNGKSVDRDGNPVGYGTGPV--GEPGTTDQHSFGQLLHQGTRDIPVTFIAVAEPHHDIPD-----LLLANL 376
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 434 laQTEALMAGKTVDEARTELSKAglcgneldnlLPHKVFVGNRPTNSIVVKKVSPFTLGALIALYEHKIFVQGIIWDINS 513
Cdd:COG0166 377 --QGLALLAGKTLDEVLALAAEA----------TPHALFPGNRPSNTILLPKLTPYTLGALIALYEHAVFVQGVLWGINP 444
|
490 500 510 520
....*....|....*....|....*....|....*....|..
gi 706912 514 FDQWGVELGKQLAKAIEPELDhcNEVSTHDSSTNGLINFIKA 555
Cdd:COG0166 445 FDQPGVELGKKLAFALLGKLG--GEEAAAGDSTEALLKRLRA 484
|
|
| SIS_PGI_2 |
cd05016 |
Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification ... |
338-529 |
1.06e-90 |
|
Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of glucose 6-phosphate to fructose 6-phosphate. As an extracellular protein, PGI also has functions equivalent to neuroleukin (NLK), autocrine motility factor (AMF), and maturation factor (MF). Evidence suggests that PGI, NLK, AMF, and MF are closely related or identical. NLK is a neurotrophic growth factor that promotes regeneration and survival of neurons. The dimeric form of NLK has isomerase function, whereas its monomeric form carries out neurotrophic activity. AMF is a cytokine that stimulates cell migration and metastasis. MF mediates the differentiation of human myeloid leukemic HL-60 cells to terminal monocytic cells.
Pssm-ID: 240147 Cd Length: 164 Bit Score: 275.63 E-value: 1.06e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 338 ETHALLPYDQYLHRFAAYFQQGDMESNGKFVSKSGKPvkYSTGPIVWGEPGTNGQHAFYQLIHQGTRLIPCDFIAPAQTH 417
Cdd:cd05016 1 KTHALLPYSQRLERFPAWLQQLDMESNGKSVTRDGED--YPTGPIPWGAPGTNDQHSFFQLIHQGTKDKPVDFIAVKKPQ 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 418 ----NPIAGGKHHKILLSNFLAQTEALMagktvdeartelskaglcgneldnllphkvFVGNRPTNSIVVKKVSPFTLGA 493
Cdd:cd05016 79 ndvlDYLAGKTLHDLLLANCLATREALM------------------------------FPGGRPSNTIVLPELTPYTLGA 128
|
170 180 190
....*....|....*....|....*....|....*.
gi 706912 494 LIALYEHKIFVQGIIWDINSFDQWGVELGKQLAKAI 529
Cdd:cd05016 129 LLALYEHKTAVQGALLGINPFDQPGVELGKKLAKKI 164
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| pgi |
PRK00179 |
glucose-6-phosphate isomerase; Reviewed |
7-556 |
0e+00 |
|
glucose-6-phosphate isomerase; Reviewed
Pssm-ID: 234679 Cd Length: 548 Bit Score: 1047.07 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 7 PLNQEAAFQKLQEYYDsKGKDLNIKDLFVKDSKRFSKYSLRLhtqndGEILLDYSKNRINDEVWDLLLTLAKVRRVNAAR 86
Cdd:PRK00179 4 NLTQTPAWQALQAHAD-EIKDVHLRDLFAADPDRFERFSLTA-----GGLLLDYSKNRITDETLALLLDLAREAGLEGAR 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 87 DAMFSGQHINITENRAVLHTALRNRGTDPVLVDDKDVMPDVRAELAHMKEFTNMVISGVWRGCTGKQITDVVNIGIGGSD 166
Cdd:PRK00179 78 DAMFAGEKINTTEDRAVLHTALRNPSNTPILVDGQDVMPEVHAVLARMKAFAEAVRSGEWKGYTGKAITDVVNIGIGGSD 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 167 LGPLMVTEALKPYGK-GLHSHFVSNIDGTHLAEVLKKVNYETTLFIVASKTFTTQETITNATSAKTWLLEHSKEPESVAK 245
Cdd:PRK00179 158 LGPVMVTEALRPYADpGLRVHFVSNVDGAHLAETLKKLDPETTLFIVASKTFTTQETLTNAHSARDWFLAAGGDEAAVAK 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 246 HFVALSTNKEKVTEFGIDSTNMFGFWDWVGGRYSLWSAIGLSICLSIGFENFEQLLDGAHFMDNHFKTTPFEKNAPVILA 325
Cdd:PRK00179 238 HFVAVSTNAEAVAEFGIDPDNMFGFWDWVGGRYSLWSAIGLSIALAIGPDNFEELLAGAHAMDEHFRTAPLEKNLPVLLA 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 326 LLGVWYSNFFKAETHALLPYDQYLHRFAAYFQQGDMESNGKFVSKSGKPVKYSTGPIVWGEPGTNGQHAFYQLIHQGTRL 405
Cdd:PRK00179 318 LIGVWYRNFFGAQSHAVLPYDQYLHRFPAYLQQLEMESNGKSVDRDGTPVDYQTGPIIWGEPGTNGQHAFFQLLHQGTKL 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 406 IPCDFIAPAQTHNPIAGgkHHKILLSNFLAQTEALMAGKTVDEARTELSKAGLCGNELDNLLPHKVFVGNRPTNSIVVKK 485
Cdd:PRK00179 398 VPADFIAPAQPHNPLGD--HHDLLLANCFAQTEALMFGKTAEEVRAELRAKGLDEAEAEELAPHKVFPGNRPSTTILLDR 475
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 706912 486 VSPFTLGALIALYEHKIFVQGIIWDINSFDQWGVELGKQLAKAIEPELDHCNEVSTHDSSTNGLINFIKAN 556
Cdd:PRK00179 476 LTPFTLGALIALYEHKVFVQGVIWGINSFDQWGVELGKQLAKRILPELEGDSEASAHDSSTNGLINRYRAW 546
|
|
| PGI |
pfam00342 |
Phosphoglucose isomerase; Phosphoglucose isomerase catalyzes the interconversion of ... |
59-550 |
0e+00 |
|
Phosphoglucose isomerase; Phosphoglucose isomerase catalyzes the interconversion of glucose-6-phosphate and fructose-6-phosphate.
Pssm-ID: 395271 Cd Length: 487 Bit Score: 866.40 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 59 DYSKNRINDEVWDLLLTLAKVRRVNAARDAMFSGQHINITENRAVLHTALRNRGTDPVLVDDKDVMPDVRAELAHMKEFT 138
Cdd:pfam00342 1 DYSKNHINDEILTALVKLAEERGVDAAREAMFNGEKINSTENRAVLHVALRNRSNTPIYVDGKDVMPEVNAVLAKMKSFS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 139 NMVISGVWRGCTGKQITDVVNIGIGGSDLGPLMVTEALKPY-GKGLHSHFVSNIDGTHLAEVLKKVNYETTLFIVASKTF 217
Cdd:pfam00342 81 ERVRSGEWKGYTGKAITDVVNIGIGGSDLGPVMVTEALKPYsGRDLDVHFVSNVDGTHIAEVLKKLNPETTLFIVASKTF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 218 TTQETITNATSAKTWLLEHSKEPESVAKHFVALSTNKEKVTEFGIDSTNMFGFWDWVGGRYSLWSAIGLSICLSIGFENF 297
Cdd:pfam00342 161 TTAETMTNAESAKEWLLKALKDDSAVAKHFIALSTNAEKVEEFGIDTKNMFEFWDWVGGRYSLWSAIGLPIALSIGFENF 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 298 EQLLDGAHFMDNHFKTTPFEKNAPVILALLGVWYSNFFKAETHALLPYDQYLHRFAAYFQQGDMESNGKFVSKSGKPVKY 377
Cdd:pfam00342 241 QQLLEGAHAMDKHFLSAPPEKNIPVLLALLGVWYNNFFGAQTHAILPYDQYLHRFPAYLQQLDMESNGKYVTRDGVLVDH 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 378 STGPIVWGEPGTNGQHAFYQLIHQGTRLIPCDFIAPAQTHNPIAgGKHHKILLSNFLAQTEALMAGKTVDEARTELSKAg 457
Cdd:pfam00342 321 QTGPIIFGEPGTNGQHAFYQLIHQGTRLIPCDFIGAVQSQNPEN-GDHHKILLSNFFAQTEALMVGKSPEEVRKELAAA- 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 458 lcgnELDNLLPHKVFVGNRPTNSIVVKKVSPFTLGALIALYEHKIFVQGIIWDINSFDQWGVELGKQLAKAIEPELDHCN 537
Cdd:pfam00342 399 ----DVEHLIPHKTFTGNRPSNSILVQKLTPATLGALIAMYEHKIFVQGAIWGINSFDQWGVELGKVLAKSILPELENSN 474
|
490
....*....|...
gi 706912 538 EVSTHDSSTNGLI 550
Cdd:pfam00342 475 KVSSHDSSTNGLI 487
|
|
| Pgi |
COG0166 |
Glucose-6-phosphate isomerase [Carbohydrate transport and metabolism]; Glucose-6-phosphate ... |
36-555 |
0e+00 |
|
Glucose-6-phosphate isomerase [Carbohydrate transport and metabolism]; Glucose-6-phosphate isomerase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439936 Cd Length: 484 Bit Score: 765.45 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 36 KDSKRFSKYSLRLhtqndGEILLDYSKNRINDEVWDLLLTLAKVRrvnAARDAMFSGQHINITENRAVLHTALRNRGTDp 115
Cdd:COG0166 8 QHLRRFERFSLEA-----AGLLLDYSKNRITDETLELLLELAEEE---EAREALFAGEKINPTEGRAVLHGALRLPEAG- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 116 vlvddKDVMPDVRAELAHMKEFTNMVIsgvwrgcTGKQITDVVNIGIGGSDLGPLMVTEALKPYGK-GLHSHFVSNIDGT 194
Cdd:COG0166 79 -----EDVMPEVREELARIKAFAEKVR-------TGKRITDVVNIGIGGSDLGPRAVIEALKPYFRdGPRVHFVSNVDPD 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 195 HLAEVLKKVNYETTLFIVASKTFTTQETITNATSAKTWLLEHSKEpeSVAKHFVALSTNKEKVTEFGIDS-TNMFGFWDW 273
Cdd:COG0166 147 YLAELLAGLDPETTLFIVISKSGTTQETLTNARVAREWLEKAGGE--DAAKHFVAVTDNAGALRAFGIDEgYNTFPFPDW 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 274 VGGRYSLWSAIGLSICLSIGFEnFEQLLDGAHFMDNHFKTTPFEKNAPVILALLGVWYSNFFKAETHALLPYDQYLHRFA 353
Cdd:COG0166 225 VGGRYSVLSAVGLLPAAAIGID-FEELLAGAHAMDEHFRTAPLEENPPVLLALLGIWYRNFKGAETEAVLPYDQRLERFP 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 354 AYFQQGDMESNGKFVSKSGKPVKYSTGPIvwGEPGTNGQHAFYQLIHQGTRLIPCDFIAPAQTHNPIAGgkhhkILLSNF 433
Cdd:COG0166 304 AWLQQLWMESNGKSVDRDGNPVGYGTGPV--GEPGTTDQHSFGQLLHQGTRDIPVTFIAVAEPHHDIPD-----LLLANL 376
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 434 laQTEALMAGKTVDEARTELSKAglcgneldnlLPHKVFVGNRPTNSIVVKKVSPFTLGALIALYEHKIFVQGIIWDINS 513
Cdd:COG0166 377 --QGLALLAGKTLDEVLALAAEA----------TPHALFPGNRPSNTILLPKLTPYTLGALIALYEHAVFVQGVLWGINP 444
|
490 500 510 520
....*....|....*....|....*....|....*....|..
gi 706912 514 FDQWGVELGKQLAKAIEPELDhcNEVSTHDSSTNGLINFIKA 555
Cdd:COG0166 445 FDQPGVELGKKLAFALLGKLG--GEEAAAGDSTEALLKRLRA 484
|
|
| PLN02649 |
PLN02649 |
glucose-6-phosphate isomerase |
12-556 |
0e+00 |
|
glucose-6-phosphate isomerase
Pssm-ID: 215351 [Multi-domain] Cd Length: 560 Bit Score: 692.55 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 12 AAFQKLQEYYDSKGKdLNIKDLFvKDSKRFSKYSLrlhtQNDGeILLDYSKNRINDEVWDLLLTLAKVRRVNAARDAMFS 91
Cdd:PLN02649 12 PAWKRLVAHVYQIKK-THLRELL-NDAERCQSMIA----EFDG-IYLDYSRQRVTDETMELLFPLAEAANLFEKIEAMFS 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 92 GQHINITENRAVLHTALRNRGTDPVLVDDKDVMPDVRAELAHMKEFTNMVISGVWRGCTGKQITDVVNIGIGGSDLGPLM 171
Cdd:PLN02649 85 GEIINSTEDRAVLHVALRAPRLAPILVDGKNVVPEVWEVLDKIKAFSEDVRSGKWKGATGKRFTNVVSIGIGGSFLGPLF 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 172 VTEALKPYGKGLHS------HFVSNIDGTHLAEVLKKVNYETTLFIVASKTFTTQETITNATSAKTWLLEhSKEPESVAK 245
Cdd:PLN02649 165 VHEALATDPEALKSakgrklRFLANVDPVDIARQIAQLDPETTLVVVVSKTFTTAETMLNARTVRKWLRD-ALGGLAVAK 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 246 HFVALSTNKEKVTEFGIDSTNMFGFWDWVGGRYSLWSAIG-LSICLSIGFENFEQLLDGAHFMDNHFKTTPFEKNAPVIL 324
Cdd:PLN02649 244 HMVAVSTNLLLVNKFGIDPWNAFPFWDWVGGRYSVCSAVGlLPLSLQYGFDVVEEFLEGAASMDEHFRTAPLKENIPVLL 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 325 ALLGVWYSNFFKAETHALLPYDQYLHRFAAYFQQGDMESNGKFVSKSGKPVKYSTGPIVWGEPGTNGQHAFYQLIHQGtR 404
Cdd:PLN02649 324 GLLSVWNSSFLGYPARAILPYSQALLKFAPHIQQLDMESNGKGVDLDGNPLPVNTGEIDFGEPGTNGQHSFYQLIHQG-R 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 405 LIPCDFIAPAQTHNPI-----AGGKHHKILLSNFLAQTEALMAGKTVDEARTElskaglcgNELDNLLPHKVFVGNRPTN 479
Cdd:PLN02649 403 NIPCDFIGVVRSQQPVhlwlgEGVSNHDELMSNFFAQPDALAYGKTPEQLRAE--------GVPEELIPHKVFAGNRPSL 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 480 SIVVKKVSPFTLGALIALYEHKIFVQGIIWDINSFDQWGVELGKQLAKAIEPELD----HCNEVSTHDSSTNGLINFIKA 555
Cdd:PLN02649 475 SILLPELTAYTVGQLLALYEHRVAVQGFIWNINSFDQWGVELGKALAKRVRAVLNeartKGEPVEGFNSSTTALLNHYLA 554
|
.
gi 706912 556 N 556
Cdd:PLN02649 555 N 555
|
|
| PTZ00430 |
PTZ00430 |
glucose-6-phosphate isomerase; Provisional |
6-529 |
0e+00 |
|
glucose-6-phosphate isomerase; Provisional
Pssm-ID: 185612 Cd Length: 552 Bit Score: 592.76 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 6 PPLNQEAAFQKLQeYYDSKGKDLNIKDLfVKDSKRFSKYslrlhTQNDGEILLDYSKNRINDEVWDLLLTLAKVRRVNAA 85
Cdd:PTZ00430 1 PDLESLKSYKNLL-SLAEKLKKVHLRDL-LKDEERNKSL-----IKEFKGVTLDLSRQRLDEETLKLLIELAEEAKLKEK 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 86 RDAMFSGQHINITENRAVLHTALRNRGTDPVLVDDKDVMPDVRAELAHMKEFTNMVISGVWRGCTGKQITDVVNIGIGGS 165
Cdd:PTZ00430 74 IKDMFNGEKINTTENRAVLHTALRAPRGEKVVVDGKNVLEDVHEVLDRIKKFSDKIRSGEILGSTGKKLKNVICIGIGGS 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 166 DLGPLMVTEALKPYG------KGLHSHFVSNIDGTHLAEVLKKVNYETTLFIVASKTFTTQETITNATSAKTWLLEHSKE 239
Cdd:PTZ00430 154 YLGTEFVYEALRTYGeareasKGRKLRFLANVDPIDVRRATEGLDPEETLVVIISKTFTTAETMLNAKTVRQWLLDNIKS 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 240 PESVAKHFVALSTNKEKVTEFGIDSTNMFGFWDWVGGRYSLWSAIGLsICLSI--GFENFEQLLDGAHFMDNHFKTTPFE 317
Cdd:PTZ00430 234 KEALSKHLCAVSTNLKLTSEFGIPDENVFGFWDWVGGRFSVTSAVGI-LPLSIqfGYDIVQQFLNGCHDMDEHFRTAPLE 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 318 KNAPVILALLGVWYSNFFKAETHALLPYDQYLHRFAAYFQQGDMESNGKFVSKSGKPVKYSTGPIVWGEPGTNGQHAFYQ 397
Cdd:PTZ00430 313 ENLPVLLGLTSFYNSTFLGYNCVAILPYCQALLKFPAHVQQLLMESNGKSVTLDGNTLDYNTGEIYFGEPGTNGQHSFYQ 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 398 LIHQGtRLIPCDFIAPAQTHNPI--AGGK--HHKILLSNFLAQTEALMAGKTVDEARTElskaglcgNELDNLLPHKVFV 473
Cdd:PTZ00430 393 LLHQG-RVVPSEFIGFAKSQNPIklLGEPvsNHDELMSNFFAQPDALAFGKTYEELEKE--------GVPEELIPHKVFP 463
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*.
gi 706912 474 GNRPTNSIVVKKVSPFTLGALIALYEHKIFVQGIIWDINSFDQWGVELGKQLAKAI 529
Cdd:PTZ00430 464 GNRPSLLLLFPELNPYTIGQLLALYEHRTVVEGFLWNINSFDQWGVELGKVLAKDV 519
|
|
| pgi |
PRK14095 |
glucose-6-phosphate isomerase; Provisional |
8-540 |
2.19e-147 |
|
glucose-6-phosphate isomerase; Provisional
Pssm-ID: 237608 Cd Length: 533 Bit Score: 434.44 E-value: 2.19e-147
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 8 LNQEAAFQKLQEyydSKGKDLNIKDLFVKDSKRFSKYSLrlhtqnDGEIL-LDYSKNRINDEVWDLLLTLAKVRRVNAAR 86
Cdd:PRK14095 7 FLDLESFKILQE---LAPEPLDLTLPGVLSEERIKKYSL------SGEGFtYNYATERVDDRILAALQNLADEAELIEKM 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 87 DAMFSGQHIN-----ITENRAVLHTALRNRGTDPVLVDDKdvmPDVRA----ELAHMKEFTNMVISGVWRGCTGKQITDV 157
Cdd:PRK14095 78 KAMQNGAVINriegfPSENRPVLHTATRGQVGDSVLTDEA---EDMAEfskrELERLAEFLKKVRSGEIKNSNGKKFTTV 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 158 VNIGIGGSDLGPLMVTEALKPYGK-GLHSHFVSNIDGTHLAEVLKKVNYETTLFIVASKTFTTQETITNATSAKTWLLEH 236
Cdd:PRK14095 155 VQIGIGGSDLGPKALYLALKNYAKkDKRVHFISNVDPDDAAEVLSEIDLAKTLFIVVSKSGTTLETAANEEFVRDALKKA 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 237 SKEPesvAKHFVALST------NKEKVTEFgidstnmFGFWDWVGGRYSLWSAIGLS-ICLSIGFENFEQLLDGAHFMDN 309
Cdd:PRK14095 235 GLDY---KKHFIAVTSegspmdDESGYLEV-------FHMWDSIGGRFSSTSMVGGVvLGFAFGFEVFKEFLKGAAAMDK 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 310 HFKTTPFEKNAPVILALLGVWYSNFFKAETHALLPYDQYLHRFAAYFQQGDMESNGKFVSKSGKPVKYSTGPIVWGEPGT 389
Cdd:PRK14095 305 AALNPNIRENLPLLAALIGIWNRNFLGYPTTAVIPYSQALERFPAHLQQLDMESNGKSVNRFGEPINFKTGPIIWGEPGT 384
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 390 NGQHAFYQLIHQGTRLIPCDFIAPAQTHN----PIAGGKHHKILLSNFLAQTEALMAGKtvdeartelskaglcgnelDN 465
Cdd:PRK14095 385 NGQHSFFQLLHQGTDIVPVEFIGFKESQLgqdiVIQGSTSQQKLFANLIAQIIALACGK-------------------EN 445
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 706912 466 LLPHKVFVGNRPTNSIVVKKVSPFTLGALIALYEHKIFVQGIIWDINSFDQWGVELGKQLAKAIEPELDHCNEVS 540
Cdd:PRK14095 446 TNPNKNFKGNRPSSLLVAKQLTPYTLGALLAHYENKVMFQGFCWNINSFDQEGVQLGKVLANQILGIMKGEAPGE 520
|
|
| SIS_PGI_2 |
cd05016 |
Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification ... |
338-529 |
1.06e-90 |
|
Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of glucose 6-phosphate to fructose 6-phosphate. As an extracellular protein, PGI also has functions equivalent to neuroleukin (NLK), autocrine motility factor (AMF), and maturation factor (MF). Evidence suggests that PGI, NLK, AMF, and MF are closely related or identical. NLK is a neurotrophic growth factor that promotes regeneration and survival of neurons. The dimeric form of NLK has isomerase function, whereas its monomeric form carries out neurotrophic activity. AMF is a cytokine that stimulates cell migration and metastasis. MF mediates the differentiation of human myeloid leukemic HL-60 cells to terminal monocytic cells.
Pssm-ID: 240147 Cd Length: 164 Bit Score: 275.63 E-value: 1.06e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 338 ETHALLPYDQYLHRFAAYFQQGDMESNGKFVSKSGKPvkYSTGPIVWGEPGTNGQHAFYQLIHQGTRLIPCDFIAPAQTH 417
Cdd:cd05016 1 KTHALLPYSQRLERFPAWLQQLDMESNGKSVTRDGED--YPTGPIPWGAPGTNDQHSFFQLIHQGTKDKPVDFIAVKKPQ 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 418 ----NPIAGGKHHKILLSNFLAQTEALMagktvdeartelskaglcgneldnllphkvFVGNRPTNSIVVKKVSPFTLGA 493
Cdd:cd05016 79 ndvlDYLAGKTLHDLLLANCLATREALM------------------------------FPGGRPSNTIVLPELTPYTLGA 128
|
170 180 190
....*....|....*....|....*....|....*.
gi 706912 494 LIALYEHKIFVQGIIWDINSFDQWGVELGKQLAKAI 529
Cdd:cd05016 129 LLALYEHKTAVQGALLGINPFDQPGVELGKKLAKKI 164
|
|
| SIS_PGI_1 |
cd05015 |
Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification ... |
128-290 |
9.22e-76 |
|
Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of glucose 6-phosphate to fructose 6-phosphate. As an extracellular protein, PGI also has functions equivalent to neuroleukin (NLK), autocrine motility factor (AMF), and maturation factor (MF). Evidence suggests that PGI, NLK, AMF, and MF are closely related or identical. NLK is a neurotrophic growth factor that promotes regeneration and survival of neurons. The dimeric form of NLK has isomerase function, whereas its monomeric form carries out neurotrophic activity. AMF is a cytokine that stimulates cell migration and metastasis. MF mediates the differentiation of human myeloid leukemic HL-60 cells to terminal monocytic cells.
Pssm-ID: 240146 Cd Length: 158 Bit Score: 237.04 E-value: 9.22e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 128 RAELAHMKEFTNMVISGvwrgctgKQITDVVNIGIGGSDLGPLMVTEALKPYGK-GLHSHFVSNIDGTHLAEVLKKVNYE 206
Cdd:cd05015 1 RAELERIKEFAEKVRSG-------KKITDVVVIGIGGSDLGPRAVYEALKPYFKgGLRLHFVSNVDPDDLAELLKKLDPE 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 207 TTLFIVASKTFTTQETITNATSAKTWLLEHSKepESVAKHFVALSTNKEKVTE-FGIDSTNMFGFWDWVGGRYS-LWSAI 284
Cdd:cd05015 74 TTLFIVISKSGTTLETLANARLAREWLEEAGG--DDLAKHFVAITDNGSGLLKkAGIEGLNTFEIPDWVGGRFSvLSSVG 151
|
....*.
gi 706912 285 GLSICL 290
Cdd:cd05015 152 GLPLAL 157
|
|
| pgi |
PRK14096 |
glucose-6-phosphate isomerase; Provisional |
39-529 |
1.38e-56 |
|
glucose-6-phosphate isomerase; Provisional
Pssm-ID: 237609 [Multi-domain] Cd Length: 528 Bit Score: 198.19 E-value: 1.38e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 39 KRFSKYslrLHTQNDGEILLDYSKNRINDevwDLLLTLA-KVRRVNAARDAMFSGQHINITENRAVLHTALRNrgtdPVL 117
Cdd:PRK14096 8 QRYCDW---LYYHPELGLWLDISRMNFDD---AFLESLEpKFQKAFAAMAALEAGAIANPDEGRMVGHYWLRN----PEL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 118 VDDKDVMPDVRAELAHMKEFTNMVISGVWRGCTGKQITDVVNIGIGGSDLGPLMVTEALKPYGKGLHSHFVSNIDGTHLA 197
Cdd:PRK14096 78 APTPEIRAEITETLAQIEAFAAKVHSGTIKPPNGEKFTDVLWIGIGGSALGPQFVAEALQPNSDGLNIHFIDNTDPDGID 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 198 EVLKKV--NYETTLFIVASKTFTTQETITNATSAKTWLLEHSKEpesVAKHFVAlstnkekVTefGIDST---------- 265
Cdd:PRK14096 158 RVLAELgdRLATTLVVVISKSGGTPETRNGMLEAKAAYEAAGLD---FASHAVA-------IT--MKGSKldqlaqsegw 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 266 -NMFGFWDWVGGRYSLWSAIGLSICLSIGfENFEQLLDGAHFMDNHFKTTPFEKNAPVILALlgVWYsnffkaetHA--- 341
Cdd:PRK14096 226 lARFPMWDWVGGRTSETSAVGLLPAALQG-IDIRAFLAGAKQMDEATRVPDLKNNPAALLAL--AWY--------YAgdg 294
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 342 -------LLPYDQYLHRFAAYFQQGDMESNGKFVSKSGKPVkySTGPIVWGEPGTNGQHAFYQLIHQGTRLIPCDFIA-- 412
Cdd:PRK14096 295 kgkkdmvVLPYKDRLLLFSRYLQQLVMESLGKELDLDGNVV--HQGIAVYGNKGSTDQHAYVQQLRDGVDNFFVTFIEvl 372
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 413 --PAQTHNPIAGGKHHKILLSNFLAQTealmagktvdeaRTELSKaglcgneldnllphkvfvGNRPTNSIVVKKVSPFT 490
Cdd:PRK14096 373 edRQGSSIEVEPGVTSGDYLSGFLQGT------------RQALYE------------------NGRQSITITIPEVNPRT 422
|
490 500 510
....*....|....*....|....*....|....*....
gi 706912 491 LGALIALYEHKIFVQGIIWDINSFDQWGVELGKQLAKAI 529
Cdd:PRK14096 423 LGALIALFERAVGLYASLVNINAYHQPGVEAGKKAAAAI 461
|
|
| PRK00973 |
PRK00973 |
glucose-6-phosphate isomerase; Provisional |
152-529 |
1.04e-34 |
|
glucose-6-phosphate isomerase; Provisional
Pssm-ID: 179193 [Multi-domain] Cd Length: 446 Bit Score: 136.28 E-value: 1.04e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 152 KQITDVVNIGIGGSDLGPLMVTEALKPYGKGLHS---------HFVSNIDGTHLAEVLKKVNYETTLFIVASKTFTTQET 222
Cdd:PRK00973 69 KNFDNVVVLGIGGSALGNLALHYALNPLNWNELSkeerngprvFVLDNVDPEKTASILDVIDLEKTLFNVISKSGNTAET 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 223 ITNATSAKTwLLEhsKEPESVAKHFVALsTNKEK------VTEFGIDstnMFGFWDWVGGRYSLWSAIGL--SICLSIgf 294
Cdd:PRK00973 149 LANYLIIRG-ILE--KLGLDPKKHLVFT-TDPEKgklkkiAEKEGYR---TLEIPENVGGRFSVLTPVGLapAAALGI-- 219
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 295 eNFEQLLDGAHFMDNHFKTTPFEKNAPVILALLGVWYSNFFKaETHALLPYDQYLHRFAAYFQQGDMESNGK-FVSKSgk 373
Cdd:PRK00973 220 -DIEELLEGAKEMDKICEKEDIFKNPALLNALIHYLYYNRGK-NISVMMPYSERLKYFGDWYRQLWAESLGKkGVGQT-- 295
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 374 PVKystgpivwgEPGTNGQHAFYQLIHQG------TRLIPCDF---IAPAQTHNPIAGGKHhkillsnflaqtealMAGK 444
Cdd:PRK00973 296 PVK---------ALGATDQHSQLQLYMEGpkdkiiTFLKVEKYrrdVEIPYEYEDIEELSY---------------LGGH 351
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 445 TVdearTELSKAGLCGNEldNLLPHKvfvgNRPTNSIVVKKVSPFTLGALIALYEHKIFVQGIIWDINSFDQWGVELGKQ 524
Cdd:PRK00973 352 KL----SELINSEQKGTE--IALTEN----GRPNVKITLDELNEYTVGQLFYMYEMQTAFMGELLNINAFDQPGVELGKK 421
|
....*
gi 706912 525 LAKAI 529
Cdd:PRK00973 422 ITYAL 426
|
|
| PRK03868 |
PRK03868 |
glucose-6-phosphate isomerase; Provisional |
154-527 |
2.64e-30 |
|
glucose-6-phosphate isomerase; Provisional
Pssm-ID: 235168 Cd Length: 410 Bit Score: 122.74 E-value: 2.64e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 154 ITDVVNIGIGGSDLGPLMVTEALKPY---GKGLHshFVSNIDGTHLAEVLKKVNYETTLFIVASKTFTTQETItnatSAK 230
Cdd:PRK03868 58 IKNIVVIGIGGSSLGVKAIYSFLKNEknnKKELH--FLENTDPISINKTLSKINLENTLFIVISKSGTTIETI----SIF 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 231 TWLLEHSKEPESVAKHFVALSTNKEKVTEFG-IDSTNMFGFWDWVGGRYSLWSAIG---LSIClsiGFeNFEQLLDGAHF 306
Cdd:PRK03868 132 KYLLSHFKLDQELKKNFLFITDPDSKLEQFAkENNIKCFNIPKNVGGRFSVLSAVGivpLALC---GY-DIKALLEGAKA 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 307 MDNHFkttpFEKNAPVIL--ALLGVWYSNFFKaeTHALLPYDQYLHRFAAYFQQGDMESNGKfvsKSGKPVKYSTGPIvw 384
Cdd:PRK03868 208 CKDSF----FEQKEDHILkkAYFYATHKNAYN--INVLFSYSDALKGFNDWYVQLWGESLGK---KQGYKTRVGLTPI-- 276
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 385 GEPGTNGQHAFYQLIHQGTRLIPCDFIAPAQTHNPIaggkhhKI--LLSNFLAQTEALmagktvdeartelskAGLCGNE 462
Cdd:PRK03868 277 GLIGSRDQHSFLQLIMEGPRDKTVTFIKIKDFQNAP------KIpnISLKGLESLDFV---------------NGVSFNE 335
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 706912 463 LDNL----LPHKVFVGNRPTNSIVVKKVSPFTLGALIALYEHKIFVQGIIWDINSFDQWGVELGKQLAK 527
Cdd:PRK03868 336 LINAqcdaTMEALIAEDIPVDVITLEKLDEFSIGYLIYYYELLTSAVGKMLGINTYDQPGVEVGKRILK 404
|
|
| pgi |
PRK14097 |
glucose-6-phosphate isomerase; Provisional |
128-524 |
4.94e-16 |
|
glucose-6-phosphate isomerase; Provisional
Pssm-ID: 184504 Cd Length: 448 Bit Score: 80.65 E-value: 4.94e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 128 RAELAHMKEftnmvISGVWRgctgKQITDVVNIGIGGSDLGPLMVTEAL---------KPYGKGLHSHFVSN-IDGTHLA 197
Cdd:PRK14097 56 KEEFARIKK-----AAEKIK----SDSDVLVVIGIGGSYLGARAAIEFLnhsfynllpKEQRKAPQIIFAGNsISSTYLA 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 198 EVLKKVNYETTLFIVASKTFTTQETITNATSAKTWLleHSKEPESVAKHFVALSTNKEKVTEFGIDSTN---MFGFWDWV 274
Cdd:PRK14097 127 DLLEYLKDKDFSINVISKSGTTTEPAIAFRIFKELL--EKKYGKEEAKKRIYATTDKAKGALKTLADAEgyeTFVIPDDV 204
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 275 GGRYSLWSAIGLsicLSIGFENF--EQLLDGAHFMDNHFKTTPFEKNAPVILALLGVW-YSNFFKAEthALLPYDQYLHR 351
Cdd:PRK14097 205 GGRFSVLTAVGL---LPIAVAGIdiDALMKGAADARKDYSSSDLSENPAYQYAAVRNIlYRKGYTTE--ILVNYEPSLQY 279
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 352 FAAYFQQGDMESNGK-----FVSKsgkpVKYSTGpivwgepgtngQHAFYQLIHQGTRLIpcdFIAPAQTHNPiaggkHH 426
Cdd:PRK14097 280 FSEWWKQLFGESEGKdqkgiFPAS----ANFSTD-----------LHSLGQYIQEGRRNL---FETVIKVEKP-----RK 336
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 427 KILLS---------NFLAqtealmaGKTVDEARTelsKAglcgnELDNLLPHkvFVGNRPTNSIVVKKVSPFTLGALIAL 497
Cdd:PRK14097 337 DLTIPedeedldglNYLA-------GKTVDFVNK---KA-----FEGTLLAH--TDGGVPNIVVNIPELDEYTFGYLVYF 399
|
410 420
....*....|....*....|....*..
gi 706912 498 YEHKIFVQGIIWDINSFDQWGVELGKQ 524
Cdd:PRK14097 400 FEKACAISGYLLGVNPFDQPGVEAYKK 426
|
|
| PRK09533 |
PRK09533 |
bifunctional transaldolase/phosoglucose isomerase; Validated |
127-307 |
3.09e-12 |
|
bifunctional transaldolase/phosoglucose isomerase; Validated
Pssm-ID: 236551 [Multi-domain] Cd Length: 948 Bit Score: 69.61 E-value: 3.09e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 127 VRAELAHMKEFTNMVisgvwRGCTGKQITDVVNIGIGGSDLGPlmvtEAL-KPYGKG-----LHShfvsnIDGTHLAEVL 200
Cdd:PRK09533 433 VEDELAHLAEYEAFA-----EEVRAEGFTDAVVLGMGGSSLGP----EVLaETFGQRdgfpkLHV-----LDSTDPAQVR 498
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 201 ---KKVNYETTLFIVASKTFTTQEtiTNATSAKTWLLEHSKEPESVAKHFVALS---TNKEKVTEfgidstnMFGFWDW- 273
Cdd:PRK09533 499 aleAAVDLARTLFIVSSKSGGTLE--PNIFKDYFFARVKEVLGAKAGRHFVAVTdpgSSLEKVAK-------EDGFRKIf 569
|
170 180 190
....*....|....*....|....*....|....*....
gi 706912 274 -----VGGRYSLWSAIGLSICLSIGFEnFEQLLDGAHFM 307
Cdd:PRK09533 570 hgdpdIGGRYSVLSPFGLVPAAAAGID-VRALLDSALAM 607
|
|
| SIS |
cd04795 |
SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and ... |
348-440 |
7.55e-03 |
|
SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars.
Pssm-ID: 240112 [Multi-domain] Cd Length: 87 Bit Score: 35.81 E-value: 7.55e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 706912 348 YLHRFAAYFQQGDMEsngkfvsksgkpvkySTGPIVWGEPGTNGQHAFyqLIHQGTRLIPCDFIAPAQTHnpiaggkhhk 427
Cdd:cd04795 8 GSGAIAAYFALELLE---------------LTGIEVVALIATELEHAS--LLSLLRKGDVVIALSYSGRT---------- 60
|
90
....*....|...
gi 706912 428 ILLSNFLAQTEAL 440
Cdd:cd04795 61 EELLAALEIAKEL 73
|
|
| |
