|
Name |
Accession |
Description |
Interval |
E-value |
| PRK13578 |
PRK13578 |
ornithine decarboxylase; Provisional |
1-711 |
0e+00 |
|
ornithine decarboxylase; Provisional
Pssm-ID: 237434 [Multi-domain] Cd Length: 720 Bit Score: 1659.33 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 1 MKSMNIAASSELVSRLSSHRRVVALGDTDFTDVAAVVITAADSRSGILALLKRTGFHLPVFLYSEHAVELPAGVTAVING 80
Cdd:PRK13578 1 MKSLKIAASRELPSCFSTHREVVALDQTDFTDVAAVVLSVADSRSGILALIKRTGFGIPVFVATEEEEEVPAEVLPRISG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 81 --------NEQQWLELESAACQYEENLLPPFYDTLTQYVEMGNSTFACPGHQHGAFFKKHPAGRHFYDFFGENVFRADMC 152
Cdd:PRK13578 81 vfelcesnNEFYGRQLETAASKYEENLLPPFFDTLTDYVEMGNSTFDCPGHQGGQFFRKHPAGRQFYDFFGENLFRADMC 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 153 NADVKLGDLLIHEGSAKDAQKFAAKVFHADKTYFVLNGTSAANKVVTNALLTRGDLVLFDRNNHKSNHHGALIQAGATPV 232
Cdd:PRK13578 161 NADVKLGDLLIHEGAAKDAQKHAAKVFNADKTYFVLNGTSASNKVVTNALLTPGDLVLFDRNNHKSNHHGALIQAGATPV 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 233 YLEASRNPFGFIGGIDAHCFNEEYLRQQIRDVAPEKADLPRPYRLAIIQLGTYDGTVYNARQVIDTVGHLCDYILFDSAW 312
Cdd:PRK13578 241 YLETARNPFGFIGGIDAHCFDEEYLREQIREVAPERADEARPFRLAVIQLGTYDGTIYNARQVVDKIGHLCDYILFDSAW 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 313 VGYEQFIPMMADSSPLLLELNENDPGIFVTQSVHKQQAGFSQTSQIHKKDNHIRGQARFCPHKRLNNAFMLHASTSPFYP 392
Cdd:PRK13578 321 VGYEQFIPMMADCSPLLLELNENDPGIFVTQSVHKQQAGFSQTSQIHKKDNHIKGQARYCPHKRLNNAFMLHASTSPFYP 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 393 LFAALDVNAKIHEGESGRRLWAECVEIGIEARKAILARCKLFRPFIPPVVDGKLWQDYPTSVLASDRRFFSFEPGAKWHG 472
Cdd:PRK13578 401 LFAALDVNAKMHEGESGRRLWMECVKLGIEARKLILARCKLIRPFIPPVVDGKPWQDYPTEQIASDLRFFSFEPGEKWHG 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 473 FEGYAADQYFVDPCKLLLTTPGIDAETGEYSDFGVPATILAHYLRENGIVPEKCDLNSILFLLTPAESHEKLAQLVAMLA 552
Cdd:PRK13578 481 FEGYAEDQYFVDPCKLLLTTPGIDAETGEYEDFGIPATILANYLRENGIVPEKCDLNSILFLLTPAEDMAKLQQLVAMLA 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 553 QFEQHIEDDSPLVEVLPSVYNKYPVRYRDYTLRQLCQEMHDLYVSFDVKDLQKAMFRQQSFPSVVMNPQDAHSAYIRGDV 632
Cdd:PRK13578 561 RFEKHIEDDAPLAEVLPSVYKKNPERYRGYTLRQLCQEMHDLYVSHDVKQLQKEMFRKASFPRVVMNPQDANIAYIRGEV 640
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 87082193 633 ELVRIRDAEGRIAAEGALPYPPGVLCVVPGEVWGGAVQRYFLALEEGVNLLPGFSPELQGVYSETDADGVKRLYGYVLK 711
Cdd:PRK13578 641 ELVRLSEAEGRIAAEGALPYPPGVLCVVPGEIWGGAVQRYFLALEEGINLLPGFAPELQGVYLETDADGRKRAYGYVLK 719
|
|
| ODC_inducible |
TIGR04301 |
ornithine decarboxylase SpeF; Members of this family are known or trusted examples of ... |
1-711 |
0e+00 |
|
ornithine decarboxylase SpeF; Members of this family are known or trusted examples of ornithine decarboxylase, all encoded in the immediate vicinity of an ornithine-putrescine antiporter. Decarboxylation of ornithine to putrescine, followed by exchange of a putrescine for a new ornithine, is a proton-motive cycle that can be induced by low pH and protect a bacterium against transient exposure to acidic conditions.
Pssm-ID: 275113 [Multi-domain] Cd Length: 719 Bit Score: 1375.58 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 1 MKSMNIAASSELVSRLSSHRRVVALGDTDFTDVAAVVITAADSRSGILALLKRTGFHLPVFLYSEHAVELPA----GVTA 76
Cdd:TIGR04301 1 MKKLKIAVSELLPDCFSTNREVVDINNTDFTDVAAVVISVDDIKNGVLEQIEETGFGIPVFVILNDEETVPAeilpRVTG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 77 VINGNEQQ----WLELESAACQYEENLLPPFYDTLTQYVEMGNSTFACPGHQHGAFFKKHPAGRHFYDFFGENVFRADMC 152
Cdd:TIGR04301 81 VIDLNESDidfyGRQIETAATKYEEKLLPPFFGALVKYVEQGNSAFDCPGHQGGQFFRKHPAGRQFYDFFGENLFRSDLC 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 153 NADVKLGDLLIHEGSAKDAQKFAAKVFHADKTYFVLNGTSAANKVVTNALLTRGDLVLFDRNNHKSNHHGALIQAGATPV 232
Cdd:TIGR04301 161 NADVALGDLLIHEGAPCDAQQHAAKVFNADKTYFVLNGTSASNKVVLNALLTPGDLVLFDRNNHKSNHHGALIQAGATPV 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 233 YLEASRNPFGFIGGIDAHCFNEEYLRQQIRDVAPEKADLPRPYRLAIIQLGTYDGTVYNARQVIDTVGHLCDYILFDSAW 312
Cdd:TIGR04301 241 YLETARNPFGFIGGIDEHCFEEEYLRELIREVAPERAKEKRPFRLAIIQLGTYDGTIYNARQVVDKIGHLCDYILFDSAW 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 313 VGYEQFIPMMADSSPLLLELNENDPGIFVTQSVHKQQAGFSQTSQIHKKDNHIRGQARFCPHKRLNNAFMLHASTSPFYP 392
Cdd:TIGR04301 321 VGYEQFIPMMKDCSPLLLELNPEDPGILVTQSVHKQQAGFSQTSQIHKKDSHIKGQARYCNHKRFNNAFMMHASTSPFYP 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 393 LFAALDVNAKIHEGESGRRLWAECVEIGIEARKAILARCKLFRPFIPPVVDGKLWQDYPTSVLASDRRFFSFEPGAKWHG 472
Cdd:TIGR04301 401 LFAALDVNAKMHEGESGRRLWMDCVKTGIEARKLLLKNCKYIRPFIPEMVDGKPWQDYDTDQIANDLRFFNFVPGEKWHS 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 473 FEGYAADQYFVDPCKLLLTTPGIDAETGEYSDFGVPATILAHYLRENGIVPEKCDLNSILFLLTPAESHEKLAQLVAMLA 552
Cdd:TIGR04301 481 FEGYGENQYFVDPCKLLLTTPGIDAETGEYEDFGIPATILANFLRENGIIPEKCDLNSILFLLTPAEDMAKMQHLVAQIA 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 553 QFEQHIEDDSPLVEVLPSVYNKYPVRYRDYTLRQLCQEMHDLYVSFDVKDLQKAMFRQQSFPSVVMNPQDAHSAYIRGDV 632
Cdd:TIGR04301 561 RFEKLLEEDAPLAEVLPSVYKANEERYKGYTIRQLCQEMHDLYVSRNVKQLQKEMFRKAHFPEVVMNPQEANIEFVRGEA 640
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 87082193 633 ELVRIRDAEGRIAAEGALPYPPGVLCVVPGEVWGGAVQRYFLALEEGVNLLPGFSPELQGVYSETDADGVKRLYGYVLK 711
Cdd:TIGR04301 641 ELVPLEQAEGRIAAEGALPYPPGVLCVVPGEIWGGAVQQYFLALEEGINLLPGFAPELQGVYLEKDEDGRKRAYGYVLK 719
|
|
| OKR_DC_1 |
pfam01276 |
Orn/Lys/Arg decarboxylase, major domain; |
101-543 |
0e+00 |
|
Orn/Lys/Arg decarboxylase, major domain;
Pssm-ID: 396025 [Multi-domain] Cd Length: 417 Bit Score: 715.05 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 101 PPFYDTLTQYVEMGNSTFACPGHQHGAFFKKHPAGRHFYDFFGENVFRADMCNADVKLGDLLIHEGSAKDAQKFAAKVFH 180
Cdd:pfam01276 1 PPLYKALFKYVRRGNYTFHCPGHQGGAGFQKHPAGRFFYDFFGENLLRIDVCIEDVELGDLLDHEGAIKEAQKYAARVFG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 181 ADKTYFVLNGTSAANKVVTNALLTRGDLVLFDRNNHKSNHHgALIQAGATPVYLEASRNPFGFIGGIDAHCFNEEYLRQQ 260
Cdd:pfam01276 81 ADKSYFVVNGTSGSNKTVGMAVCTPGDTILIDRNCHKSIHH-ALMLSGATPVYLEPSRNAYGIIGGIPLHEFQEETLKEA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 261 IRDVAPEKAdlprpYRLAIIQLGTYDGTVYNARQVIDTVGHLCDYILFDSAWVGYEQFIPMMADSSPLLLElNENDPGIF 340
Cdd:pfam01276 160 IAEVPDAKG-----PRLAVITNPTYDGVLYNAKEIVDTLHHLSDPILFDSAWVGYEQFIPIYADASPMGGE-NENGPGIF 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 341 VTQSVHKQQAGFSQTSQIHKKDNHIrgqarfCPHKRLNNAFMLHASTSPFYPLFAALDVNAKIHEGESGRRLWAECVEIG 420
Cdd:pfam01276 234 VTQSVHKLLAALSQASYIHKKEGHI------VNHDRFNEAFMMHATTSPSYPIFASLDVAAKMLEGNSGRRLWNECVERA 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 421 IEARKAI--LARCKLFRPFIPPVVDGKLwqdyptsvlasdrrFFSFEPGAKWHGFEGYAADQYFVDPCKLLLTTPGIDaE 498
Cdd:pfam01276 308 IEFRKAIdtLNNCEFFRPWNPEIVDGKE--------------CWPFHPGETWHGFEGYADNQYFLDPCKLTILTPGMD-E 372
|
410 420 430 440
....*....|....*....|....*....|....*....|....*
gi 87082193 499 TGEYSDFGVPATILAHYLRENGIVPEKCDLNSILFLLTPAESHEK 543
Cdd:pfam01276 373 DGEYSEFGVPATIVAKWLRENGIVPEKTDLNNILFLFTPGEDRTK 417
|
|
| LdcC |
COG1982 |
Arginine/lysine/ornithine decarboxylase [Amino acid transport and metabolism]; |
95-694 |
0e+00 |
|
Arginine/lysine/ornithine decarboxylase [Amino acid transport and metabolism];
Pssm-ID: 441585 [Multi-domain] Cd Length: 486 Bit Score: 587.85 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 95 YEENLLPPFYDTLTQYVEMGNSTFACPGHQHGAFFkkhpaGRHFYDFFGENVFRADMCNaDVKLGDLLIHEGSAKDAQKF 174
Cdd:COG1982 1 YMDQLLTPLFDALKKYAERGPVSFHVPGHKGGRGF-----GREFYDFFGENVFRLDLTE-LPGLDDLHDPEGVIKEAQEL 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 175 AAKVFHADKTYFVLNGTSAANKVVTNALLTRGDLVLFDRNNHKSNHHGaLIQAGATPVYLE-ASRNPFGFIGGIDAHCFN 253
Cdd:COG1982 75 AAEAFGADRTFFLVNGTSSGNKAMILAVCGPGDKVLVPRNCHKSVIHG-LILSGAIPVYLNpEIDNELGIIGGITPEAVE 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 254 EEYLRQqirdvapekadlPRPyRLAIIQLGTYDGTVYNARQVIDTVGHLCDYILFDSAWVGYEQFIPMMAdSSPLLLeln 333
Cdd:COG1982 154 EALIEH------------PDA-KAVLITNPTYYGVCYDLKAIAELAHEHGIPVLVDEAHGAHFGFHPDLP-RSAMEA--- 216
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 334 endPGIFVTQSVHKQQAGFSQTSQIHKKDNHIrgqarfcPHKRLNNAFMLHASTSPFYPLFAALDVNAKIHEGEsGRRLW 413
Cdd:COG1982 217 ---GADLVVQSTHKTLGALTQSSMLHVKGGRV-------DHERVNEALMLLQSTSPSYLLMASLDVARRQMAGE-GEELL 285
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 414 AECVEIGIEARKAILARcKLFRPFIPPVVDGKlwqdyptsvlasdrrffsfepgakwhgfegyaaDQYFVDPCKLLLTTP 493
Cdd:COG1982 286 DEALELAIEARKEINKI-PGLYVFGPEDLGAP---------------------------------GVYDLDPTKLTIDVP 331
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 494 GIdaetgeysdfGVPATILAHYLREN-GIVPEKCDLNSILFLLTPAESHEKLAQLVAMLAQFEQHIEDDSPLVEVLPSVY 572
Cdd:COG1982 332 GL----------GISGYEVAEYLREEyGIQVELADLYNILFLLSLGDTKEDIERLVAALKELKRLYDKNAPLEEVLPLAF 401
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 573 NKypvryrdytlrqlcqemhdlyvsfdvkdlqkamfrqqsFPSVVMNPQDAHsayiRGDVELVRIRDAEGRIAAEGALPY 652
Cdd:COG1982 402 PP--------------------------------------LPELVMSPREAF----FAETELVPLEEAVGRIAAEMVIPY 439
|
570 580 590 600
....*....|....*....|....*....|....*....|...
gi 87082193 653 PPGVLCVVPGEVWGGAVQRYFLALEEGVNLLPGFS-PELQGVY 694
Cdd:COG1982 440 PPGIPLLMPGERITEEVIDYLRALEEAGGRFPGFEdPELRTIR 482
|
|
| Orn_deC_like |
cd00615 |
Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent ... |
102-427 |
5.20e-124 |
|
Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine decarboxylase (LDC). ODC is a dodecamer composed of six homodimers and catalyzes the decarboxylation of tryptophan. ADC catalyzes the decarboxylation of arginine and LDC catalyzes the decarboxylation of lysine. Members of this family are widely found in all three forms of life.
Pssm-ID: 99739 [Multi-domain] Cd Length: 294 Bit Score: 371.20 E-value: 5.20e-124
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 102 PFYDTLTQYVEMGNSTFACPGHQHGAFFKKHpagrhFYDFFGENVFRADMCNaDVKLGDLLIHEGSAKDAQKFAAKVFHA 181
Cdd:cd00615 1 PLFEALKEYAKRGIISFHVPGHKGGRGFRKS-----FYEFYGENLFKADVTE-LTGLDDLLDPTGPIKEAQELAARAFGA 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 182 DKTYFVLNGTSAANKVVTNALLTRGDLVLFDRNNHKSNHHGALIqAGATPVYLEASRNP-FGFIGGIDAHCFNEEYLRQQ 260
Cdd:cd00615 75 KHTFFLVNGTSSSNKAVILAVCGPGDKILIDRNCHKSVINGLVL-SGAVPVYLKPERNPyYGIAGGIPPETFKKALIEHP 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 261 irdvapekadlprPYRLAIIQLGTYDGTVYNARQVIDTVGHLCDYILFDSAWVGYEQFIPMMADSSPLLlelnendPGIF 340
Cdd:cd00615 154 -------------DAKAAVITNPTYYGICYNLRKIVEEAHHRGLPVLVDEAHGAHFRFHPILPSSAAMA-------GADI 213
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 341 VTQSVHKQQAGFSQTSQIHKKDNHIrgqarfcPHKRLNNAFMLHASTSPFYPLFAALDVNAKIHeGESGRRLWAECVEIG 420
Cdd:cd00615 214 VVQSTHKTLPALTQGSMIHVKGDLV-------NPDRVNEALNLHQSTSPSYLILASLDVARAMM-ALEGKELVEELIELA 285
|
....*..
gi 87082193 421 IEARKAI 427
Cdd:cd00615 286 LYARQEI 292
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK13578 |
PRK13578 |
ornithine decarboxylase; Provisional |
1-711 |
0e+00 |
|
ornithine decarboxylase; Provisional
Pssm-ID: 237434 [Multi-domain] Cd Length: 720 Bit Score: 1659.33 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 1 MKSMNIAASSELVSRLSSHRRVVALGDTDFTDVAAVVITAADSRSGILALLKRTGFHLPVFLYSEHAVELPAGVTAVING 80
Cdd:PRK13578 1 MKSLKIAASRELPSCFSTHREVVALDQTDFTDVAAVVLSVADSRSGILALIKRTGFGIPVFVATEEEEEVPAEVLPRISG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 81 --------NEQQWLELESAACQYEENLLPPFYDTLTQYVEMGNSTFACPGHQHGAFFKKHPAGRHFYDFFGENVFRADMC 152
Cdd:PRK13578 81 vfelcesnNEFYGRQLETAASKYEENLLPPFFDTLTDYVEMGNSTFDCPGHQGGQFFRKHPAGRQFYDFFGENLFRADMC 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 153 NADVKLGDLLIHEGSAKDAQKFAAKVFHADKTYFVLNGTSAANKVVTNALLTRGDLVLFDRNNHKSNHHGALIQAGATPV 232
Cdd:PRK13578 161 NADVKLGDLLIHEGAAKDAQKHAAKVFNADKTYFVLNGTSASNKVVTNALLTPGDLVLFDRNNHKSNHHGALIQAGATPV 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 233 YLEASRNPFGFIGGIDAHCFNEEYLRQQIRDVAPEKADLPRPYRLAIIQLGTYDGTVYNARQVIDTVGHLCDYILFDSAW 312
Cdd:PRK13578 241 YLETARNPFGFIGGIDAHCFDEEYLREQIREVAPERADEARPFRLAVIQLGTYDGTIYNARQVVDKIGHLCDYILFDSAW 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 313 VGYEQFIPMMADSSPLLLELNENDPGIFVTQSVHKQQAGFSQTSQIHKKDNHIRGQARFCPHKRLNNAFMLHASTSPFYP 392
Cdd:PRK13578 321 VGYEQFIPMMADCSPLLLELNENDPGIFVTQSVHKQQAGFSQTSQIHKKDNHIKGQARYCPHKRLNNAFMLHASTSPFYP 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 393 LFAALDVNAKIHEGESGRRLWAECVEIGIEARKAILARCKLFRPFIPPVVDGKLWQDYPTSVLASDRRFFSFEPGAKWHG 472
Cdd:PRK13578 401 LFAALDVNAKMHEGESGRRLWMECVKLGIEARKLILARCKLIRPFIPPVVDGKPWQDYPTEQIASDLRFFSFEPGEKWHG 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 473 FEGYAADQYFVDPCKLLLTTPGIDAETGEYSDFGVPATILAHYLRENGIVPEKCDLNSILFLLTPAESHEKLAQLVAMLA 552
Cdd:PRK13578 481 FEGYAEDQYFVDPCKLLLTTPGIDAETGEYEDFGIPATILANYLRENGIVPEKCDLNSILFLLTPAEDMAKLQQLVAMLA 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 553 QFEQHIEDDSPLVEVLPSVYNKYPVRYRDYTLRQLCQEMHDLYVSFDVKDLQKAMFRQQSFPSVVMNPQDAHSAYIRGDV 632
Cdd:PRK13578 561 RFEKHIEDDAPLAEVLPSVYKKNPERYRGYTLRQLCQEMHDLYVSHDVKQLQKEMFRKASFPRVVMNPQDANIAYIRGEV 640
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 87082193 633 ELVRIRDAEGRIAAEGALPYPPGVLCVVPGEVWGGAVQRYFLALEEGVNLLPGFSPELQGVYSETDADGVKRLYGYVLK 711
Cdd:PRK13578 641 ELVRLSEAEGRIAAEGALPYPPGVLCVVPGEIWGGAVQRYFLALEEGINLLPGFAPELQGVYLETDADGRKRAYGYVLK 719
|
|
| ODC_inducible |
TIGR04301 |
ornithine decarboxylase SpeF; Members of this family are known or trusted examples of ... |
1-711 |
0e+00 |
|
ornithine decarboxylase SpeF; Members of this family are known or trusted examples of ornithine decarboxylase, all encoded in the immediate vicinity of an ornithine-putrescine antiporter. Decarboxylation of ornithine to putrescine, followed by exchange of a putrescine for a new ornithine, is a proton-motive cycle that can be induced by low pH and protect a bacterium against transient exposure to acidic conditions.
Pssm-ID: 275113 [Multi-domain] Cd Length: 719 Bit Score: 1375.58 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 1 MKSMNIAASSELVSRLSSHRRVVALGDTDFTDVAAVVITAADSRSGILALLKRTGFHLPVFLYSEHAVELPA----GVTA 76
Cdd:TIGR04301 1 MKKLKIAVSELLPDCFSTNREVVDINNTDFTDVAAVVISVDDIKNGVLEQIEETGFGIPVFVILNDEETVPAeilpRVTG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 77 VINGNEQQ----WLELESAACQYEENLLPPFYDTLTQYVEMGNSTFACPGHQHGAFFKKHPAGRHFYDFFGENVFRADMC 152
Cdd:TIGR04301 81 VIDLNESDidfyGRQIETAATKYEEKLLPPFFGALVKYVEQGNSAFDCPGHQGGQFFRKHPAGRQFYDFFGENLFRSDLC 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 153 NADVKLGDLLIHEGSAKDAQKFAAKVFHADKTYFVLNGTSAANKVVTNALLTRGDLVLFDRNNHKSNHHGALIQAGATPV 232
Cdd:TIGR04301 161 NADVALGDLLIHEGAPCDAQQHAAKVFNADKTYFVLNGTSASNKVVLNALLTPGDLVLFDRNNHKSNHHGALIQAGATPV 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 233 YLEASRNPFGFIGGIDAHCFNEEYLRQQIRDVAPEKADLPRPYRLAIIQLGTYDGTVYNARQVIDTVGHLCDYILFDSAW 312
Cdd:TIGR04301 241 YLETARNPFGFIGGIDEHCFEEEYLRELIREVAPERAKEKRPFRLAIIQLGTYDGTIYNARQVVDKIGHLCDYILFDSAW 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 313 VGYEQFIPMMADSSPLLLELNENDPGIFVTQSVHKQQAGFSQTSQIHKKDNHIRGQARFCPHKRLNNAFMLHASTSPFYP 392
Cdd:TIGR04301 321 VGYEQFIPMMKDCSPLLLELNPEDPGILVTQSVHKQQAGFSQTSQIHKKDSHIKGQARYCNHKRFNNAFMMHASTSPFYP 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 393 LFAALDVNAKIHEGESGRRLWAECVEIGIEARKAILARCKLFRPFIPPVVDGKLWQDYPTSVLASDRRFFSFEPGAKWHG 472
Cdd:TIGR04301 401 LFAALDVNAKMHEGESGRRLWMDCVKTGIEARKLLLKNCKYIRPFIPEMVDGKPWQDYDTDQIANDLRFFNFVPGEKWHS 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 473 FEGYAADQYFVDPCKLLLTTPGIDAETGEYSDFGVPATILAHYLRENGIVPEKCDLNSILFLLTPAESHEKLAQLVAMLA 552
Cdd:TIGR04301 481 FEGYGENQYFVDPCKLLLTTPGIDAETGEYEDFGIPATILANFLRENGIIPEKCDLNSILFLLTPAEDMAKMQHLVAQIA 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 553 QFEQHIEDDSPLVEVLPSVYNKYPVRYRDYTLRQLCQEMHDLYVSFDVKDLQKAMFRQQSFPSVVMNPQDAHSAYIRGDV 632
Cdd:TIGR04301 561 RFEKLLEEDAPLAEVLPSVYKANEERYKGYTIRQLCQEMHDLYVSRNVKQLQKEMFRKAHFPEVVMNPQEANIEFVRGEA 640
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 87082193 633 ELVRIRDAEGRIAAEGALPYPPGVLCVVPGEVWGGAVQRYFLALEEGVNLLPGFSPELQGVYSETDADGVKRLYGYVLK 711
Cdd:TIGR04301 641 ELVPLEQAEGRIAAEGALPYPPGVLCVVPGEIWGGAVQQYFLALEEGINLLPGFAPELQGVYLEKDEDGRKRAYGYVLK 719
|
|
| OKR_DC_1 |
pfam01276 |
Orn/Lys/Arg decarboxylase, major domain; |
101-543 |
0e+00 |
|
Orn/Lys/Arg decarboxylase, major domain;
Pssm-ID: 396025 [Multi-domain] Cd Length: 417 Bit Score: 715.05 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 101 PPFYDTLTQYVEMGNSTFACPGHQHGAFFKKHPAGRHFYDFFGENVFRADMCNADVKLGDLLIHEGSAKDAQKFAAKVFH 180
Cdd:pfam01276 1 PPLYKALFKYVRRGNYTFHCPGHQGGAGFQKHPAGRFFYDFFGENLLRIDVCIEDVELGDLLDHEGAIKEAQKYAARVFG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 181 ADKTYFVLNGTSAANKVVTNALLTRGDLVLFDRNNHKSNHHgALIQAGATPVYLEASRNPFGFIGGIDAHCFNEEYLRQQ 260
Cdd:pfam01276 81 ADKSYFVVNGTSGSNKTVGMAVCTPGDTILIDRNCHKSIHH-ALMLSGATPVYLEPSRNAYGIIGGIPLHEFQEETLKEA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 261 IRDVAPEKAdlprpYRLAIIQLGTYDGTVYNARQVIDTVGHLCDYILFDSAWVGYEQFIPMMADSSPLLLElNENDPGIF 340
Cdd:pfam01276 160 IAEVPDAKG-----PRLAVITNPTYDGVLYNAKEIVDTLHHLSDPILFDSAWVGYEQFIPIYADASPMGGE-NENGPGIF 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 341 VTQSVHKQQAGFSQTSQIHKKDNHIrgqarfCPHKRLNNAFMLHASTSPFYPLFAALDVNAKIHEGESGRRLWAECVEIG 420
Cdd:pfam01276 234 VTQSVHKLLAALSQASYIHKKEGHI------VNHDRFNEAFMMHATTSPSYPIFASLDVAAKMLEGNSGRRLWNECVERA 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 421 IEARKAI--LARCKLFRPFIPPVVDGKLwqdyptsvlasdrrFFSFEPGAKWHGFEGYAADQYFVDPCKLLLTTPGIDaE 498
Cdd:pfam01276 308 IEFRKAIdtLNNCEFFRPWNPEIVDGKE--------------CWPFHPGETWHGFEGYADNQYFLDPCKLTILTPGMD-E 372
|
410 420 430 440
....*....|....*....|....*....|....*....|....*
gi 87082193 499 TGEYSDFGVPATILAHYLRENGIVPEKCDLNSILFLLTPAESHEK 543
Cdd:pfam01276 373 DGEYSEFGVPATIVAKWLRENGIVPEKTDLNNILFLFTPGEDRTK 417
|
|
| LdcC |
COG1982 |
Arginine/lysine/ornithine decarboxylase [Amino acid transport and metabolism]; |
95-694 |
0e+00 |
|
Arginine/lysine/ornithine decarboxylase [Amino acid transport and metabolism];
Pssm-ID: 441585 [Multi-domain] Cd Length: 486 Bit Score: 587.85 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 95 YEENLLPPFYDTLTQYVEMGNSTFACPGHQHGAFFkkhpaGRHFYDFFGENVFRADMCNaDVKLGDLLIHEGSAKDAQKF 174
Cdd:COG1982 1 YMDQLLTPLFDALKKYAERGPVSFHVPGHKGGRGF-----GREFYDFFGENVFRLDLTE-LPGLDDLHDPEGVIKEAQEL 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 175 AAKVFHADKTYFVLNGTSAANKVVTNALLTRGDLVLFDRNNHKSNHHGaLIQAGATPVYLE-ASRNPFGFIGGIDAHCFN 253
Cdd:COG1982 75 AAEAFGADRTFFLVNGTSSGNKAMILAVCGPGDKVLVPRNCHKSVIHG-LILSGAIPVYLNpEIDNELGIIGGITPEAVE 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 254 EEYLRQqirdvapekadlPRPyRLAIIQLGTYDGTVYNARQVIDTVGHLCDYILFDSAWVGYEQFIPMMAdSSPLLLeln 333
Cdd:COG1982 154 EALIEH------------PDA-KAVLITNPTYYGVCYDLKAIAELAHEHGIPVLVDEAHGAHFGFHPDLP-RSAMEA--- 216
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 334 endPGIFVTQSVHKQQAGFSQTSQIHKKDNHIrgqarfcPHKRLNNAFMLHASTSPFYPLFAALDVNAKIHEGEsGRRLW 413
Cdd:COG1982 217 ---GADLVVQSTHKTLGALTQSSMLHVKGGRV-------DHERVNEALMLLQSTSPSYLLMASLDVARRQMAGE-GEELL 285
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 414 AECVEIGIEARKAILARcKLFRPFIPPVVDGKlwqdyptsvlasdrrffsfepgakwhgfegyaaDQYFVDPCKLLLTTP 493
Cdd:COG1982 286 DEALELAIEARKEINKI-PGLYVFGPEDLGAP---------------------------------GVYDLDPTKLTIDVP 331
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 494 GIdaetgeysdfGVPATILAHYLREN-GIVPEKCDLNSILFLLTPAESHEKLAQLVAMLAQFEQHIEDDSPLVEVLPSVY 572
Cdd:COG1982 332 GL----------GISGYEVAEYLREEyGIQVELADLYNILFLLSLGDTKEDIERLVAALKELKRLYDKNAPLEEVLPLAF 401
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 573 NKypvryrdytlrqlcqemhdlyvsfdvkdlqkamfrqqsFPSVVMNPQDAHsayiRGDVELVRIRDAEGRIAAEGALPY 652
Cdd:COG1982 402 PP--------------------------------------LPELVMSPREAF----FAETELVPLEEAVGRIAAEMVIPY 439
|
570 580 590 600
....*....|....*....|....*....|....*....|...
gi 87082193 653 PPGVLCVVPGEVWGGAVQRYFLALEEGVNLLPGFS-PELQGVY 694
Cdd:COG1982 440 PPGIPLLMPGERITEEVIDYLRALEEAGGRFPGFEdPELRTIR 482
|
|
| PRK15029 |
PRK15029 |
arginine decarboxylase; Provisional |
88-693 |
2.11e-138 |
|
arginine decarboxylase; Provisional
Pssm-ID: 184989 [Multi-domain] Cd Length: 755 Bit Score: 424.64 E-value: 2.11e-138
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 88 LESAACQYEENLLPPFYDTLTQYVEMGNSTFACPGHQHGAFFKKHPAGRHFYDFFGENVFRADMCNADVKLGDLLIHEGS 167
Cdd:PRK15029 127 AVAAMTRYRQQLLPPLFSALMKYSDIHEYSWAAPGHQGGVGFTKTPAGRFYHDYYGENLFRTDMGIERTSLGSLLDHTGA 206
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 168 AKDAQKFAAKVFHADKTYFVLNGTSAANKVVTNALLTRGDLVLFDRNNHKSNHHGaLIQAGATPVYLEASRNPFGFIGGI 247
Cdd:PRK15029 207 FGESEKYAARVFGADRSWSVVVGTSGSNRTIMQACMTDNDVVVVDRNCHKSIEQG-LILTGAKPVYMVPSRNRYGIIGPI 285
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 248 DAHCFNEEYLRQQIRD--VAPEKADLPRPYrlAIIQLGTYDGTVYNARQVIDTVGHLCDYILFDSAWVGYEQFIPMMADS 325
Cdd:PRK15029 286 YPQEMQPETLQKKISEspLTKDKAGQKPSY--CVVTNCTYDGVCYNAKEAQDLLEKTSDRLHFDEAWYGYARFNPIYADH 363
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 326 SPLLLE-LNENDPGIFVTQSVHKQQAGFSQTSQIHKKDNhiRGQARFcphKRLNNAFMLHASTSPFYPLFAALDVNAKIH 404
Cdd:PRK15029 364 YAMRGEpGDHNGPTVFATHSTHKLLNALSQASYIHVREG--RGAINF---SRFNQAYMMHATTSPLYAICASNDVAVSMM 438
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 405 EGESGRRLWAECVEIGIEARKAiLARCK---------LFRPFIPPVV----DGKL--WQDYPTSVLASDRRFFSFEPGAK 469
Cdd:PRK15029 439 DGNSGLSLTQEVIDEAVDFRQA-MARLYkeftadgswFFKPWNKEVVtdpqTGKTydFADAPTKLLTTVQDCWVMHPGES 517
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 470 WHGFEGYAADQYFVDPCKLLLTTPGIdAETGEYSDFGVPATILAHYLRENGIVPEKCDLNSILFLLTPAESHEKLAQLVA 549
Cdd:PRK15029 518 WHGFKDLPDNWSMLDPIKVSILAPGM-GEDGELEETGVPAALVTAWLGRHGIVPTRTTDFQIMFLFSMGVTRGKWGTLVN 596
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 550 MLAQFEQHIEDDSPLVEVLPSVYNKYPVRYRDYTLRQLCQEMHDLYVSFDVKDLQKAMFrqQSFPSVVMNPQDAHSAYIR 629
Cdd:PRK15029 597 TLCSFKRHYDANTPLAQVMPELVEQYPDTYANMGIHDLGDTMFAWLKENNPGARLNEAY--SGLPVAEITPREAYNAIVD 674
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 87082193 630 GDVELVRIRDAEGRIAAEGALPYPPGVLCVVPGEVWG---GAVQRYFLALEEGVNLLPGFSPELQGV 693
Cdd:PRK15029 675 NNVELVSIENLPGRIAANSVIPYPPGIPMLLSGENFGdknSPQVSYLRSLQSWDHHFPGFEHETEGT 741
|
|
| PRK15399 |
PRK15399 |
lysine decarboxylase; |
94-711 |
1.10e-125 |
|
lysine decarboxylase;
Pssm-ID: 185297 [Multi-domain] Cd Length: 713 Bit Score: 390.25 E-value: 1.10e-125
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 94 QYEENLLPPFYDTLTQYVEMGNSTFACPGHQHGAFFKKHPAGRHFYDFFGENVFRADMCNADVKLGDLLIHEGSAKDAQK 173
Cdd:PRK15399 123 EYLDNITPPFTKALFTYVKEGKYTFCTPGHMGGTAYQKSPVGCLFYDFFGGNTLKADVSISVTELGSLLDHTGPHLEAEE 202
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 174 FAAKVFHADKTYFVLNGTSAANKVVTNALLTRGDLVLFDRNNHKSNHHgALIQAGATPVYLEASRNPFGFIGGIDAHCFN 253
Cdd:PRK15399 203 YIARTFGAEQSYIVTNGTSTSNKIVGMYAAPAGSTLLIDRNCHKSLAH-LLMMSDVVPIWLKPTRNALGILGGIPRREFT 281
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 254 EEYLRQQIRDVApeKADLPRPyrlAIIQLGTYDGTVYNArqviDTVGHLCDY--ILFDSAWVGYEQFIPMMADSSPLlle 331
Cdd:PRK15399 282 RDSIEEKVAATT--QAQWPVH---AVITNSTYDGLLYNT----DWIKQTLDVpsIHFDSAWVPYTHFHPIYQGKSGM--- 349
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 332 LNENDPG--IFVTQSVHKQQAGFSQTSQIhkkdnHIRGQARfcpHKRLNNAFMLHASTSPFYPLFAALDVNAKIHEGESG 409
Cdd:PRK15399 350 SGERVPGkvIFETQSTHKMLAAFSQASLI-----HIKGEYD---EETFNEAFMMHTSTSPSYPIVASVETAAAMLRGNPG 421
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 410 RRLWAECVEIGIEARKAILarcKLFRPfippvVDG---KLWQdyPTSVlaSDRRFFSFEPGAKWHGFEGYAADQYFVDPC 486
Cdd:PRK15399 422 KRLINRSVERALHFRKEVQ---RLREE-----SDGwffDIWQ--PENV--DEAECWPVAPGEQWHGFKDADADHMFLDPV 489
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 487 KLLLTTPGIDaETGEYSDFGVPATILAHYLRENGIVPEKCDLNSILFLLTPAESHEKLAQLVAMLAQFEQHIEDDSPLVE 566
Cdd:PRK15399 490 KVTILTPGMD-EQGNMSEEGIPAALVAKFLDERGIVVEKTGPYNLLFLFSIGIDKTKAMGLLRGLTEFKRAYDLNLRVKN 568
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 567 VLPSVYNKYPVRYRDYTLRQLCQEMHDLYVSFDVKDLqkaMFRQ-QSFPSVVMNPQDAHSAYIRGDVELVRIRDAEGRIA 645
Cdd:PRK15399 569 MLPDLYAEDPDFYRNMRIQDLAQGIHKLIRKHDLPGL---MLRAfDVLPEMIMTPHQAWQRQIKGEVETVALEQLVGRVS 645
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 87082193 646 AEGALPYPPGVLCVVPGEVW---GGAVQRYFLALEEGVNLLPGFSPELQGVYSetDADGvkRLYGYVLK 711
Cdd:PRK15399 646 ANMILPYPPGVPLLMPGEMIteeSRAVLDFLLMLCSIGQHYPGFETDIHGAKR--DEDG--VYRVRVLK 710
|
|
| Orn_deC_like |
cd00615 |
Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent ... |
102-427 |
5.20e-124 |
|
Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine decarboxylase (LDC). ODC is a dodecamer composed of six homodimers and catalyzes the decarboxylation of tryptophan. ADC catalyzes the decarboxylation of arginine and LDC catalyzes the decarboxylation of lysine. Members of this family are widely found in all three forms of life.
Pssm-ID: 99739 [Multi-domain] Cd Length: 294 Bit Score: 371.20 E-value: 5.20e-124
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 102 PFYDTLTQYVEMGNSTFACPGHQHGAFFKKHpagrhFYDFFGENVFRADMCNaDVKLGDLLIHEGSAKDAQKFAAKVFHA 181
Cdd:cd00615 1 PLFEALKEYAKRGIISFHVPGHKGGRGFRKS-----FYEFYGENLFKADVTE-LTGLDDLLDPTGPIKEAQELAARAFGA 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 182 DKTYFVLNGTSAANKVVTNALLTRGDLVLFDRNNHKSNHHGALIqAGATPVYLEASRNP-FGFIGGIDAHCFNEEYLRQQ 260
Cdd:cd00615 75 KHTFFLVNGTSSSNKAVILAVCGPGDKILIDRNCHKSVINGLVL-SGAVPVYLKPERNPyYGIAGGIPPETFKKALIEHP 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 261 irdvapekadlprPYRLAIIQLGTYDGTVYNARQVIDTVGHLCDYILFDSAWVGYEQFIPMMADSSPLLlelnendPGIF 340
Cdd:cd00615 154 -------------DAKAAVITNPTYYGICYNLRKIVEEAHHRGLPVLVDEAHGAHFRFHPILPSSAAMA-------GADI 213
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 341 VTQSVHKQQAGFSQTSQIHKKDNHIrgqarfcPHKRLNNAFMLHASTSPFYPLFAALDVNAKIHeGESGRRLWAECVEIG 420
Cdd:cd00615 214 VVQSTHKTLPALTQGSMIHVKGDLV-------NPDRVNEALNLHQSTSPSYLILASLDVARAMM-ALEGKELVEELIELA 285
|
....*..
gi 87082193 421 IEARKAI 427
Cdd:cd00615 286 LYARQEI 292
|
|
| PRK15400 |
PRK15400 |
lysine decarboxylase; |
86-698 |
4.14e-117 |
|
lysine decarboxylase;
Pssm-ID: 185298 [Multi-domain] Cd Length: 714 Bit Score: 367.64 E-value: 4.14e-117
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 86 LELESAACQYEENLLPPFYDTLTQYVEMGNSTFACPGHQHGAFFKKHPAGRHFYDFFGENVFRADMCNADVKLGDLLIHE 165
Cdd:PRK15400 115 NKIKQTTDEYIDTILPPLTKALFKYVREGKYTFCTPGHMGGTAFQKSPVGSLFYDFFGPNTMKSDISISVSELGSLLDHS 194
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 166 GSAKDAQKFAAKVFHADKTYFVLNGTSAANKVVTNALLTRGDLVLFDRNNHKSNHHgALIQAGATPVYLEASRNPFGFIG 245
Cdd:PRK15400 195 GPHKEAEEYIARVFNADRSYMVTNGTSTANKIVGMYSAPAGSTVLIDRNCHKSLTH-LMMMSDVTPIYFRPTRNAYGILG 273
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 246 GIDAHCFNEEYLRQQIRDVApeKADLPRpyrLAIIQLGTYDGTVYNARQVIDTVGhlCDYILFDSAWVGYEQFIPMMADS 325
Cdd:PRK15400 274 GIPQSEFQHATIAKRVKETP--NATWPV---HAVITNSTYDGLLYNTDFIKKTLD--VKSIHFDSAWVPYTNFSPIYEGK 346
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 326 SPLLlelNENDPG--IFVTQSVHKQQAGFSQTSQIHKKDNHIRgqarfcphKRLNNAFMLHASTSPFYPLFAALDVNAKI 403
Cdd:PRK15400 347 CGMS---GGRVEGkvIYETQSTHKLLAAFSQASMIHVKGDVNE--------ETFNEAYMMHTTTSPHYGIVASTETAAAM 415
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 404 HEGESGRRLWAECVEIGIEARKAIlARCK------LFRPFIPPVVDG-KLWQdyptsvlasdrrffsFEPGAKWHGFEGY 476
Cdd:PRK15400 416 MKGNAGKRLINGSIERAIKFRKEI-KRLRtesdgwFFDVWQPDHIDTtECWP---------------LRSDSTWHGFKNI 479
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 477 AADQYFVDPCKLLLTTPGIDAEtGEYSDFGVPATILAHYLRENGIVPEKCDLNSILFLLTPAESHEKLAQLVAMLAQFEQ 556
Cdd:PRK15400 480 DNEHMYLDPIKVTLLTPGMKKD-GTMSDFGIPASIVAKYLDEHGIVVEKTGPYNLLFLFSIGIDKTKALSLLRALTDFKR 558
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 557 HIEDDSPLVEVLPSVYNKYPVRYRDYTLRQLCQEMHDLYVSFDVKDLqkaMFRQ-QSFPSVVMNPQDAHSAYIRGDVELV 635
Cdd:PRK15400 559 AFDLNLRVKNMLPSLYREDPEFYENMRIQELAQNIHKLIVHHNLPDL---MYRAfEVLPTMVMTPYAAFQKELHGMTEEV 635
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 87082193 636 RIRDAEGRIAAEGALPYPPGVLCVVPGEVWGGA---VQRYFLALEEGVNLLPGFSPELQGVYSETD 698
Cdd:PRK15400 636 YLDEMVGRVNANMILPYPPGVPLVMPGEMITEEsrpVLEFLQMLCEIGAHYPGFETDIHGAYRQAD 701
|
|
| OKR_DC_1_C |
pfam03711 |
Orn/Lys/Arg decarboxylase, C-terminal domain; |
568-698 |
1.63e-68 |
|
Orn/Lys/Arg decarboxylase, C-terminal domain;
Pssm-ID: 461020 [Multi-domain] Cd Length: 132 Bit Score: 220.47 E-value: 1.63e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 568 LPSVYNKYPVRYRDYTLRQLCQEMHDLYVSFDVKDLQKAMFRqqSFPSVVMNPQDAHSAYIRGDVELVRIRDAEGRIAAE 647
Cdd:pfam03711 1 LPELVAAYPERYEGMGLRDLCQEMHDFYRENNVARLQKEAFR--SLPEPAMTPAEAYQELVRGEVELVPLDELEGRIAAV 78
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 87082193 648 GALPYPPGVLCVVPGEVWG---GAVQRYFLALEEGVNLLPGFSPELQGVYSETD 698
Cdd:pfam03711 79 GVLPYPPGIPLLMPGERFGeenRPILDYLLALEEFDNRFPGFETEIHGVYREED 132
|
|
| OKR_DC_1_N |
pfam03709 |
Orn/Lys/Arg decarboxylase, N-terminal domain; This domain has a flavodoxin-like fold, and is ... |
4-95 |
1.89e-18 |
|
Orn/Lys/Arg decarboxylase, N-terminal domain; This domain has a flavodoxin-like fold, and is termed the "wing" domain because of its position in the overall 3D structure.
Pssm-ID: 427454 [Multi-domain] Cd Length: 111 Bit Score: 81.13 E-value: 1.89e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 4 MNIAASSELVSRLSS-HRRVVALGDTD--------FTDVAAVVITAADSRSGILALLKRTGFHLPVFLYSE--HAVELPA 72
Cdd:pfam03709 1 LKIAASRELAEALERtGREVVDATSTDdllaaietFTDIAAVVLSWDDYAAGLLDEIRRRNFDLPVFLLGEthTSEDVPA 80
|
90 100 110
....*....|....*....|....*....|.
gi 87082193 73 GVTAVING--------NEQQWLELESAACQY 95
Cdd:pfam03709 81 DVLRLIDGfielaedtPEFIARQIEAAAKKY 111
|
|
| AAT_I |
cd01494 |
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP) ... |
168-361 |
3.52e-16 |
|
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. Structure and sequence analysis has revealed that the PLP dependent enzymes can be classified into four major groups of different evolutionary origin: aspartate aminotransferase superfamily (fold type I), tryptophan synthase beta superfamily (fold type II), alanine racemase superfamily (fold type III), and D-amino acid superfamily (fold type IV) and Glycogen phophorylase family (fold type V).
Pssm-ID: 99742 [Multi-domain] Cd Length: 170 Bit Score: 76.65 E-value: 3.52e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 168 AKDAQKFAAKVFH--ADKTYFVLNGTsAANKVVTNALLTRGDLVLFDRNNHKSNHHGALIQAGATPVYLEASRNPFGFIG 245
Cdd:cd01494 2 LEELEEKLARLLQpgNDKAVFVPSGT-GANEAALLALLGPGDEVIVDANGHGSRYWVAAELAGAKPVPVPVDDAGYGGLD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 87082193 246 GidahcfneeylrqqirdVAPEKADLPRPYRLAIIQLGTYDGTVYNARQVIDTVGH-LCDYILFDSAWVGYEQFIPMMad 324
Cdd:cd01494 81 V-----------------AILEELKAKPNVALIVITPNTTSGGVLVPLKEIRKIAKeYGILLLVDAASAGGASPAPGV-- 141
|
170 180 190
....*....|....*....|....*....|....*..
gi 87082193 325 sspllleLNENDPGIFVTQSVHKQQAGfSQTSQIHKK 361
Cdd:cd01494 142 -------LIPEGGADVVTFSLHKNLGG-EGGGVVIVK 170
|
|
| |
