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Conserved domains on  [gi|4322916|gb|AAD16127|]
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BAG-family molecular chaperone regulator-1B protein [Schizosaccharomyces pombe]

Protein Classification

BAG family molecular chaperone regulator( domain architecture ID 10490150)

BAG (Bcl-2 associated athanogene) family molecular chaperone regulator which may function as a co-chaperone that regulates diverse cellular pathways, such as programmed cell death and stress responses; similar to Schizosaccharomyces pombe BAG family molecular chaperone regulator 1B which inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release

CATH:  1.20.58.120
Gene Ontology:  GO:0051087|GO:0006457
PubMed:  12406544
SCOP:  4002965

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
BAG pfam02179
BAG domain; Domain present in Hsp70 regulators.
 126-200 1.10e-16

BAG domain; Domain present in Hsp70 regulators.


:

Pssm-ID: 460475 [Multi-domain]  Cd Length: 77  Bit Score: 71.49  E-value: 1.10e-16
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 4322916    126 IDELQ---QDLVPKIEAFCQSSPASAQDVQdlHTRLSETLLARMIKLDAVNVEDDPEARLKRKEAIRLSQQYLSKLDS 200
Cdd:pfam02179   1 IDAILkevDKLEPQVEAFEGSPPSKKRDKE--YKRLSEMLMKLLLKLDGIDTEGDPEAREARKAAVKEVQGLLEKLDA 76
 
Name Accession Description Interval E-value
BAG pfam02179
BAG domain; Domain present in Hsp70 regulators.
 126-200 1.10e-16

BAG domain; Domain present in Hsp70 regulators.


Pssm-ID: 460475 [Multi-domain]  Cd Length: 77  Bit Score: 71.49  E-value: 1.10e-16
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 4322916    126 IDELQ---QDLVPKIEAFCQSSPASAQDVQdlHTRLSETLLARMIKLDAVNVEDDPEARLKRKEAIRLSQQYLSKLDS 200
Cdd:pfam02179   1 IDAILkevDKLEPQVEAFEGSPPSKKRDKE--YKRLSEMLMKLLLKLDGIDTEGDPEAREARKAAVKEVQGLLEKLDA 76
BAG smart00264
BAG domains, present in regulator of Hsp70 proteins; BAG domains, present in Bcl-2-associated ...
 124-202 3.95e-16

BAG domains, present in regulator of Hsp70 proteins; BAG domains, present in Bcl-2-associated athanogene 1 and silencer of death domains


Pssm-ID: 214591  Cd Length: 79  Bit Score: 70.03  E-value: 3.95e-16
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 4322916     124 AYIDELQQDLVPKIEAFCQSspASAQDVQDLHTRLSETLLARMIKLDAVNVEDDPEARLKRKEAIRLSQQYLSKLDSTK 202
Cdd:smart00264   3 KKINEVLDEVQKKIEKEVQV--ADGKKDDKEYLRLSEELMKLLLKLDSVDVEGCEDIREARKRLVRLIQNLLNALDSKK 79
 
Name Accession Description Interval E-value
BAG pfam02179
BAG domain; Domain present in Hsp70 regulators.
 126-200 1.10e-16

BAG domain; Domain present in Hsp70 regulators.


Pssm-ID: 460475 [Multi-domain]  Cd Length: 77  Bit Score: 71.49  E-value: 1.10e-16
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 4322916    126 IDELQ---QDLVPKIEAFCQSSPASAQDVQdlHTRLSETLLARMIKLDAVNVEDDPEARLKRKEAIRLSQQYLSKLDS 200
Cdd:pfam02179   1 IDAILkevDKLEPQVEAFEGSPPSKKRDKE--YKRLSEMLMKLLLKLDGIDTEGDPEAREARKAAVKEVQGLLEKLDA 76
BAG smart00264
BAG domains, present in regulator of Hsp70 proteins; BAG domains, present in Bcl-2-associated ...
 124-202 3.95e-16

BAG domains, present in regulator of Hsp70 proteins; BAG domains, present in Bcl-2-associated athanogene 1 and silencer of death domains


Pssm-ID: 214591  Cd Length: 79  Bit Score: 70.03  E-value: 3.95e-16
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 4322916     124 AYIDELQQDLVPKIEAFCQSspASAQDVQDLHTRLSETLLARMIKLDAVNVEDDPEARLKRKEAIRLSQQYLSKLDSTK 202
Cdd:smart00264   3 KKINEVLDEVQKKIEKEVQV--ADGKKDDKEYLRLSEELMKLLLKLDSVDVEGCEDIREARKRLVRLIQNLLNALDSKK 79
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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