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Conserved domains on  [gi|4884001|gb|AAD31722|]
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SEC12 [Mus musculus]

Protein Classification

WD40 repeat domain-containing protein( domain architecture ID 11455410)

WD40 repeat domain-containing protein similar to proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly

CATH:  2.130.10.10
PubMed:  10322433|8090199
SCOP:  4002744

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
WD40 COG2319
WD40 repeat [General function prediction only];
160-353 5.65e-13

WD40 repeat [General function prediction only];


:

Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 69.94  E-value: 5.65e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4884001  160 VCFNHDNTLLATGGTDGHVRVWKVPSLEKVLEFKAHEGEIGDLTLGPDGK-LVTVGWDFKASVW--QKDQLVTQLQWQEN 236
Cdd:COG2319 210 VAFSPDGKLLASGSADGTVRLWDLATGKLLRTLTGHSGSVRSVAFSPDGRlLASGSADGTVRLWdlATGELLRTLTGHSG 289

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4884001  237 GPASsntpyryqaCRFgqVPDqlgGLRLF------TVQIphkrlrqpppcyltaWDSSTFLPLRTRSCGHEVISCLSVSD 310
Cdd:COG2319 290 GVNS---------VAF--SPD---GKLLAsgsddgTVRL---------------WDLATGKLLRTLTGHTGAVRSVAFSP 340

                       170       180       190       200
                ....*....|....*....|....*....|....*....|...
gi 4884001  311 SGTFLGLGTVTGSVAIYIAFSLQRLyYVKEAHGIVVTDVTFLP 353
Cdd:COG2319 341 DGKTLASGSDDGTVRLWDLATGELL-RTLTGHTGAVTSVAFSP 382
 
Name Accession Description Interval E-value
WD40 COG2319
WD40 repeat [General function prediction only];
160-353 5.65e-13

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 69.94  E-value: 5.65e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4884001  160 VCFNHDNTLLATGGTDGHVRVWKVPSLEKVLEFKAHEGEIGDLTLGPDGK-LVTVGWDFKASVW--QKDQLVTQLQWQEN 236
Cdd:COG2319 210 VAFSPDGKLLASGSADGTVRLWDLATGKLLRTLTGHSGSVRSVAFSPDGRlLASGSADGTVRLWdlATGELLRTLTGHSG 289

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4884001  237 GPASsntpyryqaCRFgqVPDqlgGLRLF------TVQIphkrlrqpppcyltaWDSSTFLPLRTRSCGHEVISCLSVSD 310
Cdd:COG2319 290 GVNS---------VAF--SPD---GKLLAsgsddgTVRL---------------WDLATGKLLRTLTGHTGAVRSVAFSP 340

                       170       180       190       200
                ....*....|....*....|....*....|....*....|...
gi 4884001  311 SGTFLGLGTVTGSVAIYIAFSLQRLyYVKEAHGIVVTDVTFLP 353
Cdd:COG2319 341 DGKTLASGSDDGTVRLWDLATGELL-RTLTGHTGAVTSVAFSP 382
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 159-353 5.80e-11

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 62.74  E-value: 5.80e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4884001  159 VVCFNHDNTLLATGGTDGHVRVWKVPSLEKVLEFKAHEGEIGDLTLGPDGK-LVTVGWDFKASVW--QKDQLVTQLQWQE 235
Cdd:cd00200  14 CVAFSPDGKLLATGSGDGTIKVWDLETGELLRTLKGHTGPVRDVAASADGTyLASGSSDKTIRLWdlETGECVRTLTGHT 93

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4884001  236 NGPASsntpyryqaCRFgqVPDQ---LGGLRLFTVQIphkrlrqpppcyltaWDSSTFLPLRTRScGHE-VISCLSVSDS 311
Cdd:cd00200  94 SYVSS---------VAF--SPDGrilSSSSRDKTIKV---------------WDVETGKCLTTLR-GHTdWVNSVAFSPD 146

                       170       180       190       200
                ....*....|....*....|....*....|....*....|..
gi 4884001  312 GTFLGLGTVTGSVAIYiAFSLQRLYYVKEAHGIVVTDVTFLP 353
Cdd:cd00200 147 GTFVASSSQDGTIKLW-DLRTGKCVATLTGHTGEVNSVAFSP 187
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 160-182 1.22e-04

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 39.22  E-value: 1.22e-04
                           10        20
                   ....*....|....*....|...
gi 4884001     160 VCFNHDNTLLATGGTDGHVRVWK 182
Cdd:smart00320  18 VAFSPDGKYLASGSDDGTIKLWD 40
WD40 pfam00400
WD domain, G-beta repeat;
160-181 1.12e-03

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 36.55  E-value: 1.12e-03
                          10        20
                  ....*....|....*....|..
gi 4884001    160 VCFNHDNTLLATGGTDGHVRVW 181
Cdd:pfam00400  17 LAFSPDGKLLASGSDDGTVKVW 38
 
Name Accession Description Interval E-value
WD40 COG2319
WD40 repeat [General function prediction only];
160-353 5.65e-13

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 69.94  E-value: 5.65e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4884001  160 VCFNHDNTLLATGGTDGHVRVWKVPSLEKVLEFKAHEGEIGDLTLGPDGK-LVTVGWDFKASVW--QKDQLVTQLQWQEN 236
Cdd:COG2319 210 VAFSPDGKLLASGSADGTVRLWDLATGKLLRTLTGHSGSVRSVAFSPDGRlLASGSADGTVRLWdlATGELLRTLTGHSG 289

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4884001  237 GPASsntpyryqaCRFgqVPDqlgGLRLF------TVQIphkrlrqpppcyltaWDSSTFLPLRTRSCGHEVISCLSVSD 310
Cdd:COG2319 290 GVNS---------VAF--SPD---GKLLAsgsddgTVRL---------------WDLATGKLLRTLTGHTGAVRSVAFSP 340

                       170       180       190       200
                ....*....|....*....|....*....|....*....|...
gi 4884001  311 SGTFLGLGTVTGSVAIYIAFSLQRLyYVKEAHGIVVTDVTFLP 353
Cdd:COG2319 341 DGKTLASGSDDGTVRLWDLATGELL-RTLTGHTGAVTSVAFSP 382
WD40 COG2319
WD40 repeat [General function prediction only];
160-353 1.23e-12

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 68.78  E-value: 1.23e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4884001  160 VCFNHDNTLLATGGTDGHVRVWKVPSLEKVLEFKAHEGEIGDLTLGPDGK-LVTVGWDFKASVW--QKDQLVTQLQWQEN 236
Cdd:COG2319 168 VAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKlLASGSADGTVRLWdlATGKLLRTLTGHSG 247

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4884001  237 GPASsntpyryqaCRFGqvPDqlgGLRLF------TVQIphkrlrqpppcyltaWDSSTFLPLRTRSCGHEVISCLSVSD 310
Cdd:COG2319 248 SVRS---------VAFS--PD---GRLLAsgsadgTVRL---------------WDLATGELLRTLTGHSGGVNSVAFSP 298

                       170       180       190       200
                ....*....|....*....|....*....|....*....|...
gi 4884001  311 SGTFLGLGTVTGSVAIYiAFSLQRLYYVKEAHGIVVTDVTFLP 353
Cdd:COG2319 299 DGKLLASGSDDGTVRLW-DLATGKLLRTLTGHTGAVRSVAFSP 340
WD40 COG2319
WD40 repeat [General function prediction only];
160-353 4.54e-11

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 64.16  E-value: 4.54e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4884001  160 VCFNHDNTLLATGGTDGHVRVWKVPSLEKVLEFKAHEGEIGDLTLGPDGK-LVTVGWDFKASVW--QKDQLVTQLQWQEN 236
Cdd:COG2319 126 VAFSPDGKTLASGSADGTVRLWDLATGKLLRTLTGHSGAVTSVAFSPDGKlLASGSDDGTVRLWdlATGKLLRTLTGHTG 205

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4884001  237 GPassntpyryQACRFGqvPDqlgGLRLF------TVQIphkrlrqpppcyltaWDSSTFLPLRTRSCGHEVISCLSVSD 310
Cdd:COG2319 206 AV---------RSVAFS--PD---GKLLAsgsadgTVRL---------------WDLATGKLLRTLTGHSGSVRSVAFSP 256

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*
gi 4884001  311 SGTFLGLGTVTGSVAIYiafSLQ--RLYYVKEAHGIVVTDVTFLP 353
Cdd:COG2319 257 DGRLLASGSADGTVRLW---DLAtgELLRTLTGHSGGVNSVAFSP 298
WD40 COG2319
WD40 repeat [General function prediction only];
160-223 5.06e-11

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 63.78  E-value: 5.06e-11
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 4884001  160 VCFNHDNTLLATGGTDGHVRVWKVPSLEKVLEFKAHEGEIGDLTLGPDGK-LVTVGWDFKASVWQ 223
Cdd:COG2319 336 VAFSPDGKTLASGSDDGTVRLWDLATGELLRTLTGHTGAVTSVAFSPDGRtLASGSADGTVRLWD 400
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 159-353 5.80e-11

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 62.74  E-value: 5.80e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4884001  159 VVCFNHDNTLLATGGTDGHVRVWKVPSLEKVLEFKAHEGEIGDLTLGPDGK-LVTVGWDFKASVW--QKDQLVTQLQWQE 235
Cdd:cd00200  14 CVAFSPDGKLLATGSGDGTIKVWDLETGELLRTLKGHTGPVRDVAASADGTyLASGSSDKTIRLWdlETGECVRTLTGHT 93

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4884001  236 NGPASsntpyryqaCRFgqVPDQ---LGGLRLFTVQIphkrlrqpppcyltaWDSSTFLPLRTRScGHE-VISCLSVSDS 311
Cdd:cd00200  94 SYVSS---------VAF--SPDGrilSSSSRDKTIKV---------------WDVETGKCLTTLR-GHTdWVNSVAFSPD 146

                       170       180       190       200
                ....*....|....*....|....*....|....*....|..
gi 4884001  312 GTFLGLGTVTGSVAIYiAFSLQRLYYVKEAHGIVVTDVTFLP 353
Cdd:cd00200 147 GTFVASSSQDGTIKLW-DLRTGKCVATLTGHTGEVNSVAFSP 187
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 155-353 8.32e-10

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 59.27  E-value: 8.32e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4884001  155 PLQKVVCFnHDNTLLATGGTDGHVRVWKVPSLEKVLEFKAHEGEIGDLTLGPDGKLVTV-GWDFKASVW--QKDQLVTQL 231
Cdd:cd00200  53 PVRDVAAS-ADGTYLASGSSDKTIRLWDLETGECVRTLTGHTSYVSSVAFSPDGRILSSsSRDKTIKVWdvETGKCLTTL 131

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4884001  232 QWQENGPASsntpyryqaCRFGQVPDQL-GGLRLFTVQIphkrlrqpppcyltaWDSSTFLPLRTRScGHE-VISCLSVS 309
Cdd:cd00200 132 RGHTDWVNS---------VAFSPDGTFVaSSSQDGTIKL---------------WDLRTGKCVATLT-GHTgEVNSVAFS 186

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....
gi 4884001  310 DSGTFLGLGTVTGSVAIYiAFSLQRLYYVKEAHGIVVTDVTFLP 353
Cdd:cd00200 187 PDGEKLLSSSSDGTIKLW-DLSTGKCLGTLRGHENGVNSVAFSP 229
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 160-223 5.13e-09

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 56.96  E-value: 5.13e-09
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 4884001  160 VCFNHDNTLLATGGTDGHVRVWKVPSLEKVLEFKAHEGEIGDLTLGPDGK-LVTVGWDFKASVWQ 223
Cdd:cd00200 225 VAFSPDGYLLASGSEDGTIRVWDLRTGECVQTLSGHTNSVTSLAWSPDGKrLASGSADGTIRIWD 289
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 158-323 3.26e-08

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 54.65  E-value: 3.26e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4884001  158 KVVCFNHDNTLLATGGTDGHVRVWKVPSLEKVLEFKAHEGEIGDLTLGPDG-KLVTVGWDFKASVW--QKDQLVTQLQWQ 234
Cdd:cd00200 139 NSVAFSPDGTFVASSSQDGTIKLWDLRTGKCVATLTGHTGEVNSVAFSPDGeKLLSSSSDGTIKLWdlSTGKCLGTLRGH 218

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4884001  235 ENGPASsntpyryqaCRFGqvPDQL---GGLRLFTVQIphkrlrqpppcyltaWDSSTFLPLRTRScGHEV-ISCLSVSD 310
Cdd:cd00200 219 ENGVNS---------VAFS--PDGYllaSGSEDGTIRV---------------WDLRTGECVQTLS-GHTNsVTSLAWSP 271

                       170
                ....*....|...
gi 4884001  311 SGTFLglgtVTGS 323
Cdd:cd00200 272 DGKRL----ASGS 280
WD40 COG2319
WD40 repeat [General function prediction only];
162-353 3.38e-08

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 55.30  E-value: 3.38e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4884001  162 FNHDNTLLATGGTDGHVRVWKVPSLEKVLEFKAHEGEIGDLTLGPDGK-LVTVGWDFKASVW--QKDQLVTQLQWQENGP 238
Cdd:COG2319  86 FSPDGRLLASASADGTVRLWDLATGLLLRTLTGHTGAVRSVAFSPDGKtLASGSADGTVRLWdlATGKLLRTLTGHSGAV 165

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4884001  239 ASsntpyryqaCRFGqvPDqlgGLRLF------TVQIphkrlrqpppcyltaWDSSTFLPLRTRSCGHEVISCLSVSDSG 312
Cdd:COG2319 166 TS---------VAFS--PD---GKLLAsgsddgTVRL---------------WDLATGKLLRTLTGHTGAVRSVAFSPDG 216

                       170       180       190       200
                ....*....|....*....|....*....|....*....|...
gi 4884001  313 TFLGLGTVTGSVAIYiafSLQ--RLYYVKEAHGIVVTDVTFLP 353
Cdd:COG2319 217 KLLASGSADGTVRLW---DLAtgKLLRTLTGHSGSVRSVAFSP 256
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 160-182 1.22e-04

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 39.22  E-value: 1.22e-04
                           10        20
                   ....*....|....*....|...
gi 4884001     160 VCFNHDNTLLATGGTDGHVRVWK 182
Cdd:smart00320  18 VAFSPDGKYLASGSDDGTIKLWD 40
WD40 pfam00400
WD domain, G-beta repeat;
160-181 1.12e-03

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 36.55  E-value: 1.12e-03
                          10        20
                  ....*....|....*....|..
gi 4884001    160 VCFNHDNTLLATGGTDGHVRVW 181
Cdd:pfam00400  17 LAFSPDGKLLASGSDDGTVKVW 38
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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