|
Name |
Accession |
Description |
Interval |
E-value |
| MCM |
smart00350 |
minichromosome maintenance proteins; |
106-648 |
0e+00 |
|
minichromosome maintenance proteins;
Pssm-ID: 214631 [Multi-domain] Cd Length: 509 Bit Score: 702.10 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 106 RHVTPRSLTSIYLGNMVCVEGIVTKVSLIRPKVVRS---VHYCPNTRKVMERKYTDLTSFEAVPSGAAYPTKdedgnlLE 182
Cdd:smart00350 1 KPSSIRELRADHLGKLVRISGIVTRTSGVRPKLKRAsftCEKCGATLGPEIQSGRETEPTVCPPRECQSPTP------FS 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 183 TEYGLSVYKDHQTLTIQEMPEKAPAGQLPRSVDIVCDDDLVDRCKPGDRVQIVGSYRCLP-GKRGGYTSGT--FRTVLLA 259
Cdd:smart00350 75 LNHERSTFIDFQKIKLQESPEEVPVGQLPRSVDVILDGDLVDKAKPGDRVEVTGIYRNVPyGFKLNTVKGLpvFATYIEA 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 260 NNISLLS-KESNLD-------ISREDIMLCKKLAKNNDIFELLSKSLAPSIHGHAYVKQAILCLLLGGVEKILPNGTRLR 331
Cdd:smart00350 155 NHVRKLDyKRSFEDssfsvqsLSDEEEEEIRKLSKDPDIYERLARSLAPSIYGHEDIKKAILLLLFGGVHKNLPDGMKIR 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 332 GDINVLLIGDPSVAKSQLLRYVLNTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSD 411
Cdd:smart00350 235 GDINILLCGDPGTAKSQLLKYVEKTAPRAVYTTGKGSSAVGLTAAVTRDPETREFTLEAGALVLADNGVCCIDEFDKMDD 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 412 IDRTAIHEVMEQGRVTISKAGIHASLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFVMLDVIDSDVDQM 491
Cdd:smart00350 315 SDRTAIHEAMEQQTISIAKAGITTTLNARCSVLAAANPIGGRYDPKLTPEENIDLPAPILSRFDLLFVVLDEVDEERDRE 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 492 ISDHVVRMHRYRNPKEADGEplsmgssyadslsfvssseekkdtevyekydallhgksrqrhEKILSVEFMRKYIHIAKC 571
Cdd:smart00350 395 LAKHVVDLHRYSHPEEDEAF------------------------------------------EPPLSQEKLRKYIAYARE 432
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 4903292 572 -MKPKLGEQACEAIANEYSRLRSQEAvETDVARTQPITARTLETLIRLSTAHARARMSKSVTIDDAHAAIELVQFAYF 648
Cdd:smart00350 433 kIKPKLSEEAADKLVKAYVDLRKEDS-QTESRSSIPITVRQLESIIRLSEAHAKMRLSDVVEEADVEEAIRLLRESII 509
|
|
| MCM3 |
cd17754 |
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in ... |
293-646 |
0e+00 |
|
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350660 [Multi-domain] Cd Length: 299 Bit Score: 577.50 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 293 LLSKSLAPSIHGHAYVKQAILCLLLGGVEKILPNGTRLRGDINVLLIGDPSVAKSQLLRYVLNTAPRAIPTTGRGSSGVG 372
Cdd:cd17754 1 LLSKSLAPSIYGHEYIKKAILLMLLGGVEKNLENGSHLRGDINILLVGDPSVAKSQLLRYVLNTAPLAIATTGRGSSGVG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 373 LTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRTAIHEVMEQGRVTISKAGIHASLNARCSVLAAANPVYG 452
Cdd:cd17754 81 LTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRVAIHEVMEQQTVTIAKAGIHASLNARCSVLAAANPVYG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 453 RYDQYKTPMENIGLQDSLLSRFDLLFVMLDVIDSDVDQMISDHVVRMHRYrnpkeadgeplsmgssyadslsfvssseek 532
Cdd:cd17754 161 RYDVYKTPMENIGLPDSLLSRFDLLFIVLDDIDEERDRSISEHVLRMHRY------------------------------ 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 533 kdtevyekydallhgksrqrhekilsVEFMRKYIHIAK-CMKPKLGEQACEAIANEYSRLRSQEAVETDVARTQPITART 611
Cdd:cd17754 211 --------------------------IKFLRKYIHYAKeRIKPKLTQEAAEYIAEEYADLRNDDNTKTDKARTSPITART 264
|
330 340 350
....*....|....*....|....*....|....*
gi 4903292 612 LETLIRLSTAHARARMSKSVTIDDAHAAIELVQFA 646
Cdd:cd17754 265 LETLIRLATAHAKARLSKTVDKVDAEVALNLLRFA 299
|
|
| Mcm2 |
COG1241 |
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and ... |
9-651 |
0e+00 |
|
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair];
Pssm-ID: 440854 [Multi-domain] Cd Length: 682 Bit Score: 557.11 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 9 IKDIQREYVDFLDDEEdqgiYAGHVKDMIAE--KSKRLIVNVNDLKRKNPQRALGLLSNAADEQLAFGRALKEYASTvdp 86
Cdd:COG1241 2 ESDLVDKFEEFLRRYK----YRDEILELAQEypEKRSLVVDYNDLYSFDPDLADDLLENPDEVLEAAEEALREIDLE--- 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 87 GYAKMHEDLFVGFEGCFgnRHVTPRSLTSIYLGNMVCVEGIVTKVSLIRPKVVRSVHYCPN--TRKVMERKYTDLTsfea 164
Cdd:COG1241 75 PYDVSLGDAHVRITNLP--ETVPIRDIRSDHIGKLISVEGIVRKATEVKPKITEAAFECPRcgTETYVPQTGEKLQ---- 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 165 vpsgaaYPTKD---EDGNLLETEYGLSVYKDHQTLTIQEMPEKAPAGQLPRSVDIVCDDDLVDRCKPGDRVQIVGSYRCL 241
Cdd:COG1241 149 ------EPHECpgcGRQGPFKLLPEKSEFIDAQKIRIQEPPEDLPGGQQPQSIDVILEDDLVGEVRPGDRVTVTGILRIE 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 242 PGKRGGYTSGTFRTVLLANNISLLSKES-NLDISREDIMLCKKLAKNNDIFELLSKSLAPSIHGHAYVKQAILCLLLGGV 320
Cdd:COG1241 223 QRTSGRGKSTIFDLYLEANSIEVEEKEFeEIEITEEDEEKIKELSKDPDIYEKIIASIAPSIYGYEEIKEAIALQLFGGV 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 321 EKILPNGTRLRGDINVLLIGDPSVAKSQLLRYVLNTAPRAIPTTGRGSSGVGLTAAVTTDQE-TGERRLEAGAMVLADRG 399
Cdd:COG1241 303 PKVLPDGSRIRGDIHILLVGDPGTAKSQLLRYAARLAPRGVYTSGKGSTAAGLTAAAVRDDFgTGRWTLEAGALVLADGG 382
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 400 VVCIDEFDKMSDIDRTAIHEVMEQGRVTISKAGIHASLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFV 479
Cdd:COG1241 383 LACIDELDKMREEDRSALHEAMEQQTISIAKAGIVATLNARCSVLAAANPKYGRFDPYEPIAEQIDLPPTLLSRFDLIFV 462
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 480 MLDVIDSDVDQMISDHVVRMHRyrnpkeaDGEPLsmgssyadslsfvssseEKKDTEVYEKYDAllhgksrqrhekILSV 559
Cdd:COG1241 463 LRDKPDEERDRELARHILKVHR-------AGELL-----------------EQEIEEETEEVKP------------EIDP 506
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 560 EFMRKYIHIAK-CMKPKLGEQACEAIANEYSRLRSQEAVETDvarTQPITARTLETLIRLSTAHARARMSKSVTIDDAHA 638
Cdd:COG1241 507 DLLRKYIAYARrNVFPVLTEEAKDLIEDFYVDMRKKGEDEDS---PVPITARQLEALIRLAEASARMRLSDTVTEEDAER 583
|
650
....*....|...
gi 4903292 639 AIELVQfAYFKKV 651
Cdd:COG1241 584 AIRLVD-SCLKDV 595
|
|
| minchrom_main_MCM |
NF040949 |
minichromosome maintenance protein MCM; |
14-651 |
0e+00 |
|
minichromosome maintenance protein MCM;
Pssm-ID: 468880 [Multi-domain] Cd Length: 681 Bit Score: 549.91 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 14 REYVDFLDDEEDQGIYAGHVKDMIAEKSKRLIVNVNDLKRKNPQRAlGLLSNAADEQL-AFGRALKEYASTVDPGYAKMH 92
Cdd:NF040949 6 KEFIRTFRDSFGNEKYKERIFEMIAMRKRSLVVDFNDLYMFDPELA-DLLIEKPDEVLpAASKALKEIVEEEDPEYAEEV 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 93 EDLFVGFEGCFgnRHVTPRSLTSIYLGNMVCVEGIVTKVSLIRPKVVRSVHYCPNTRKVMERKYTDLTSFEAVPSGAAYP 172
Cdd:NF040949 85 AKFHVRFRNLP--RTVPLRDLRSEYIGKLIAVEGIVTRTTPVKPRIVKAVFRCRDCGCEFEWPEEEEESYEIVEPPTVCP 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 173 TKDEDGN--LLETEyglSVYKDHQTLTIQEMPEKAPAGQLPRSVDIVCDDDLVDRCKPGDRVQIVGSYRCLPG---KRGg 247
Cdd:NF040949 163 VCGKPGSfrLLQEK---SKFIDWQKIVVQERPEELPPGQLPRSIEVVLEDDLVDTARPGDRVTVTGILRIKPDsslKKG- 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 248 yTSGTFRTVLLANNISLLSKES-NLDISREDIMLCKKLAKNNDIFELLSKSLAPSIHGHAYVKQAILCLLLGGVEKILPN 326
Cdd:NF040949 239 -SRPIFKNYIEANHIEVSQKELeEVEITEEDEEKILELAKDPWIREKIIASIAPSIYGHWEIKEAIALLLFGGVPKVLPD 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 327 GTRLRGDINVLLIGDPSVAKSQLLRYVLNTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEF 406
Cdd:NF040949 318 GTRIRGDIHVLIVGDPGTAKSQLLQYVARLAPRAVYTSGKGSTAAGLTAAVVRDKLTGEYYLEAGALVLADGGVAVIDEI 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 407 DKMSDIDRTAIHEVMEQGRVTISKAGIHASLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFVMLDVIDS 486
Cdd:NF040949 398 DKMREEDRSAIHEAMEQQTVSIAKAGIVATLNARASVLAAGNPKFGRYDPNRSVAENIDLPPTILSRFDLIFVIRDKPNE 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 487 DVDQMISDHVVRMHRyrnpkeadgeplsmgssyadslsfvssseekkdtevyekydallhGKSRQRHEkiLSVEFMRKYI 566
Cdd:NF040949 478 ERDRRLARHILDVHS---------------------------------------------GKEKVKPE--IDPDLLKKYI 510
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 567 HIA-KCMKPKLGEQACEAIANEYSRLRSQEAVETDVARTQPITARTLETLIRLSTAHARARMSKSVTIDDAHAAIELVQf 645
Cdd:NF040949 511 AYArKYVRPKLTEEAKKLIEDFYVEMRKSSKSSEDPDSPIPITARQLEALIRLSEAHAKMRLKDEVTAEDAERAIRLML- 589
|
....*.
gi 4903292 646 AYFKKV 651
Cdd:NF040949 590 AFLESV 595
|
|
| MCM |
pfam00493 |
MCM P-loop domain; |
282-500 |
3.24e-128 |
|
MCM P-loop domain;
Pssm-ID: 459830 [Multi-domain] Cd Length: 224 Bit Score: 382.26 E-value: 3.24e-128
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 282 KKLAKNNDIFELLSKSLAPSIHGHAYVKQAILCLLLGGVEKILPNGTRLRGDINVLLIGDPSVAKSQLLRYVLNTAPRAI 361
Cdd:pfam00493 6 KELAKRPDIYDKLADSIAPSIYGHEDVKKAILLQLFGGVKKILPDGTRLRGDINVLLVGDPGTAKSQLLKYVEKIAPRAV 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 362 PTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRTAIHEVMEQGRVTISKAGIHASLNARC 441
Cdd:pfam00493 86 YTSGKGSSAAGLTAAVVRDPVTGEFVLEAGALVLADGGVCCIDEFDKMNDEDRVALHEAMEQQTISIAKAGIVATLNARC 165
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 4903292 442 SVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFVMLDVIDSDVDQMISDHVVRMH 500
Cdd:pfam00493 166 SILAAANPIFGRYDPKKSIAENINLPPPLLSRFDLIFVLLDKPDEEKDERLAKHIVDLH 224
|
|
| PTZ00111 |
PTZ00111 |
DNA replication licensing factor MCM4; Provisional |
109-653 |
3.65e-83 |
|
DNA replication licensing factor MCM4; Provisional
Pssm-ID: 173403 [Multi-domain] Cd Length: 915 Bit Score: 285.35 E-value: 3.65e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 109 TPRSLTSIYLGNMVCVEGIVTKVSLIRPKVVRSVHYCPNTRKVMERKYTDLTS--FEAVPSGAAYP----TKDEDGNLLE 182
Cdd:PTZ00111 217 CVGNLEPSMADSLVQFSGTVVRQTWIVPEITMACFRCRGQKKIGLNDYQPCTCehYEYVIQGEVNEpllcNECNSKYTFE 296
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 183 TEYGLSVYKDHQTLTIQEMPEKAPAGQLP--------------------RSVDIVCDDDLVDRCKPGDRVQIVGSYRCLP 242
Cdd:PTZ00111 297 LNHNMCVYSTKKIVKLLQSNSSLNNPDKDgldnsvdnsglngeiymkdnEVINLNLYDDLIDSVKTGDRVTVVGILKVTP 376
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 243 gKRGGYTSGTFRT------------VLLANNISLLSK------ESNlDISREDIMLCKKLAKNNDIFELLSKSLAPSIHG 304
Cdd:PTZ00111 377 -IRTSTTRRTLKSlytyfvnvihvkVINSTNANQPEKglkylgNEN-DFSDLQVYKILELSRNPMIYRILLDSFAPSIKA 454
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 305 HAYVKQAILCLLLGGVE-----KILPNGT----RLRGDINVLLIGDPSVAKSQLLRYVLNTAPRAIPTTGRGSSGVGLTA 375
Cdd:PTZ00111 455 RNNVKIGLLCQLFSGNKnssdfNKSPDACykvdNFRGIINVLLCGDPGTAKSQLLHYTHLLSPRSIYTSGKSSSSVGLTA 534
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 376 AVT-TDQETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRTAIHEVMEQGRVTISKAGIHASLNARCSVLAAANPVYGRY 454
Cdd:PTZ00111 535 SIKfNESDNGRAMIQPGAVVLANGGVCCIDELDKCHNESRLSLYEVMEQQTVTIAKAGIVATLKAETAILASCNPINSRY 614
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 455 DQYKTPMENIGLQDSLLSRFDLLFVMLDVIDSDVDQMISDHVVRmhRYRNPKEADGEplSMGSSYADSLSFVSSSEEKKD 534
Cdd:PTZ00111 615 NKNKAVIENINISPSLFTRFDLIYLVLDHIDQDTDQLISLSIAK--DFLLPHMTGSG--NDEDTYDRSNTMHVEDESLRS 690
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 535 TEVYEKYDallhgksrqrhekilsVEFMRKYIHIAK--CMkPKLGEQACEAIANEYSRLR--------------SQEAVE 598
Cdd:PTZ00111 691 EKDYNKND----------------LDMLRMYIKFSKlhCF-PKLSDEAKKVITREYVKMRqgnfqtsnldelehAQEDDD 753
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 4903292 599 TDV------ARTQPITARTLETLIRLSTAHARARMSKSVTIDDAHAAIELVQFAYFKKVLD 653
Cdd:PTZ00111 754 DDLyyqssgTRMIYVSSRMISSIIRISVSLARMRLSTVVTPADALQAVQIVKSSTFQSLVD 814
|
|
| MCM_N |
pfam14551 |
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins. |
13-101 |
3.75e-13 |
|
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins.
Pssm-ID: 464206 [Multi-domain] Cd Length: 95 Bit Score: 65.78 E-value: 3.75e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 13 QREYVDFLD----DEEDQGIYAGHVKDMIAEKSKRLIVNVNDLKRKNPQRALGLLSNAADEQLAFGRALKEYASTV--DP 86
Cdd:pfam14551 1 KRKFKDFLEefreDGDGEFKYRDQLREMIEREQRSLEVDLDDLREFDPDLAEALLENPYEYLPLFEEALKEVVKELseDP 80
|
90
....*....|....*
gi 4903292 87 GYAKMHEDLFVGFEG 101
Cdd:pfam14551 81 DYAEEEKEFQVRFYN 95
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MCM |
smart00350 |
minichromosome maintenance proteins; |
106-648 |
0e+00 |
|
minichromosome maintenance proteins;
Pssm-ID: 214631 [Multi-domain] Cd Length: 509 Bit Score: 702.10 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 106 RHVTPRSLTSIYLGNMVCVEGIVTKVSLIRPKVVRS---VHYCPNTRKVMERKYTDLTSFEAVPSGAAYPTKdedgnlLE 182
Cdd:smart00350 1 KPSSIRELRADHLGKLVRISGIVTRTSGVRPKLKRAsftCEKCGATLGPEIQSGRETEPTVCPPRECQSPTP------FS 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 183 TEYGLSVYKDHQTLTIQEMPEKAPAGQLPRSVDIVCDDDLVDRCKPGDRVQIVGSYRCLP-GKRGGYTSGT--FRTVLLA 259
Cdd:smart00350 75 LNHERSTFIDFQKIKLQESPEEVPVGQLPRSVDVILDGDLVDKAKPGDRVEVTGIYRNVPyGFKLNTVKGLpvFATYIEA 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 260 NNISLLS-KESNLD-------ISREDIMLCKKLAKNNDIFELLSKSLAPSIHGHAYVKQAILCLLLGGVEKILPNGTRLR 331
Cdd:smart00350 155 NHVRKLDyKRSFEDssfsvqsLSDEEEEEIRKLSKDPDIYERLARSLAPSIYGHEDIKKAILLLLFGGVHKNLPDGMKIR 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 332 GDINVLLIGDPSVAKSQLLRYVLNTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSD 411
Cdd:smart00350 235 GDINILLCGDPGTAKSQLLKYVEKTAPRAVYTTGKGSSAVGLTAAVTRDPETREFTLEAGALVLADNGVCCIDEFDKMDD 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 412 IDRTAIHEVMEQGRVTISKAGIHASLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFVMLDVIDSDVDQM 491
Cdd:smart00350 315 SDRTAIHEAMEQQTISIAKAGITTTLNARCSVLAAANPIGGRYDPKLTPEENIDLPAPILSRFDLLFVVLDEVDEERDRE 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 492 ISDHVVRMHRYRNPKEADGEplsmgssyadslsfvssseekkdtevyekydallhgksrqrhEKILSVEFMRKYIHIAKC 571
Cdd:smart00350 395 LAKHVVDLHRYSHPEEDEAF------------------------------------------EPPLSQEKLRKYIAYARE 432
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 4903292 572 -MKPKLGEQACEAIANEYSRLRSQEAvETDVARTQPITARTLETLIRLSTAHARARMSKSVTIDDAHAAIELVQFAYF 648
Cdd:smart00350 433 kIKPKLSEEAADKLVKAYVDLRKEDS-QTESRSSIPITVRQLESIIRLSEAHAKMRLSDVVEEADVEEAIRLLRESII 509
|
|
| MCM3 |
cd17754 |
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in ... |
293-646 |
0e+00 |
|
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350660 [Multi-domain] Cd Length: 299 Bit Score: 577.50 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 293 LLSKSLAPSIHGHAYVKQAILCLLLGGVEKILPNGTRLRGDINVLLIGDPSVAKSQLLRYVLNTAPRAIPTTGRGSSGVG 372
Cdd:cd17754 1 LLSKSLAPSIYGHEYIKKAILLMLLGGVEKNLENGSHLRGDINILLVGDPSVAKSQLLRYVLNTAPLAIATTGRGSSGVG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 373 LTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRTAIHEVMEQGRVTISKAGIHASLNARCSVLAAANPVYG 452
Cdd:cd17754 81 LTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRVAIHEVMEQQTVTIAKAGIHASLNARCSVLAAANPVYG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 453 RYDQYKTPMENIGLQDSLLSRFDLLFVMLDVIDSDVDQMISDHVVRMHRYrnpkeadgeplsmgssyadslsfvssseek 532
Cdd:cd17754 161 RYDVYKTPMENIGLPDSLLSRFDLLFIVLDDIDEERDRSISEHVLRMHRY------------------------------ 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 533 kdtevyekydallhgksrqrhekilsVEFMRKYIHIAK-CMKPKLGEQACEAIANEYSRLRSQEAVETDVARTQPITART 611
Cdd:cd17754 211 --------------------------IKFLRKYIHYAKeRIKPKLTQEAAEYIAEEYADLRNDDNTKTDKARTSPITART 264
|
330 340 350
....*....|....*....|....*....|....*
gi 4903292 612 LETLIRLSTAHARARMSKSVTIDDAHAAIELVQFA 646
Cdd:cd17754 265 LETLIRLATAHAKARLSKTVDKVDAEVALNLLRFA 299
|
|
| Mcm2 |
COG1241 |
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and ... |
9-651 |
0e+00 |
|
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair];
Pssm-ID: 440854 [Multi-domain] Cd Length: 682 Bit Score: 557.11 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 9 IKDIQREYVDFLDDEEdqgiYAGHVKDMIAE--KSKRLIVNVNDLKRKNPQRALGLLSNAADEQLAFGRALKEYASTvdp 86
Cdd:COG1241 2 ESDLVDKFEEFLRRYK----YRDEILELAQEypEKRSLVVDYNDLYSFDPDLADDLLENPDEVLEAAEEALREIDLE--- 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 87 GYAKMHEDLFVGFEGCFgnRHVTPRSLTSIYLGNMVCVEGIVTKVSLIRPKVVRSVHYCPN--TRKVMERKYTDLTsfea 164
Cdd:COG1241 75 PYDVSLGDAHVRITNLP--ETVPIRDIRSDHIGKLISVEGIVRKATEVKPKITEAAFECPRcgTETYVPQTGEKLQ---- 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 165 vpsgaaYPTKD---EDGNLLETEYGLSVYKDHQTLTIQEMPEKAPAGQLPRSVDIVCDDDLVDRCKPGDRVQIVGSYRCL 241
Cdd:COG1241 149 ------EPHECpgcGRQGPFKLLPEKSEFIDAQKIRIQEPPEDLPGGQQPQSIDVILEDDLVGEVRPGDRVTVTGILRIE 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 242 PGKRGGYTSGTFRTVLLANNISLLSKES-NLDISREDIMLCKKLAKNNDIFELLSKSLAPSIHGHAYVKQAILCLLLGGV 320
Cdd:COG1241 223 QRTSGRGKSTIFDLYLEANSIEVEEKEFeEIEITEEDEEKIKELSKDPDIYEKIIASIAPSIYGYEEIKEAIALQLFGGV 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 321 EKILPNGTRLRGDINVLLIGDPSVAKSQLLRYVLNTAPRAIPTTGRGSSGVGLTAAVTTDQE-TGERRLEAGAMVLADRG 399
Cdd:COG1241 303 PKVLPDGSRIRGDIHILLVGDPGTAKSQLLRYAARLAPRGVYTSGKGSTAAGLTAAAVRDDFgTGRWTLEAGALVLADGG 382
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 400 VVCIDEFDKMSDIDRTAIHEVMEQGRVTISKAGIHASLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFV 479
Cdd:COG1241 383 LACIDELDKMREEDRSALHEAMEQQTISIAKAGIVATLNARCSVLAAANPKYGRFDPYEPIAEQIDLPPTLLSRFDLIFV 462
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 480 MLDVIDSDVDQMISDHVVRMHRyrnpkeaDGEPLsmgssyadslsfvssseEKKDTEVYEKYDAllhgksrqrhekILSV 559
Cdd:COG1241 463 LRDKPDEERDRELARHILKVHR-------AGELL-----------------EQEIEEETEEVKP------------EIDP 506
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 560 EFMRKYIHIAK-CMKPKLGEQACEAIANEYSRLRSQEAVETDvarTQPITARTLETLIRLSTAHARARMSKSVTIDDAHA 638
Cdd:COG1241 507 DLLRKYIAYARrNVFPVLTEEAKDLIEDFYVDMRKKGEDEDS---PVPITARQLEALIRLAEASARMRLSDTVTEEDAER 583
|
650
....*....|...
gi 4903292 639 AIELVQfAYFKKV 651
Cdd:COG1241 584 AIRLVD-SCLKDV 595
|
|
| minchrom_main_MCM |
NF040949 |
minichromosome maintenance protein MCM; |
14-651 |
0e+00 |
|
minichromosome maintenance protein MCM;
Pssm-ID: 468880 [Multi-domain] Cd Length: 681 Bit Score: 549.91 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 14 REYVDFLDDEEDQGIYAGHVKDMIAEKSKRLIVNVNDLKRKNPQRAlGLLSNAADEQL-AFGRALKEYASTVDPGYAKMH 92
Cdd:NF040949 6 KEFIRTFRDSFGNEKYKERIFEMIAMRKRSLVVDFNDLYMFDPELA-DLLIEKPDEVLpAASKALKEIVEEEDPEYAEEV 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 93 EDLFVGFEGCFgnRHVTPRSLTSIYLGNMVCVEGIVTKVSLIRPKVVRSVHYCPNTRKVMERKYTDLTSFEAVPSGAAYP 172
Cdd:NF040949 85 AKFHVRFRNLP--RTVPLRDLRSEYIGKLIAVEGIVTRTTPVKPRIVKAVFRCRDCGCEFEWPEEEEESYEIVEPPTVCP 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 173 TKDEDGN--LLETEyglSVYKDHQTLTIQEMPEKAPAGQLPRSVDIVCDDDLVDRCKPGDRVQIVGSYRCLPG---KRGg 247
Cdd:NF040949 163 VCGKPGSfrLLQEK---SKFIDWQKIVVQERPEELPPGQLPRSIEVVLEDDLVDTARPGDRVTVTGILRIKPDsslKKG- 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 248 yTSGTFRTVLLANNISLLSKES-NLDISREDIMLCKKLAKNNDIFELLSKSLAPSIHGHAYVKQAILCLLLGGVEKILPN 326
Cdd:NF040949 239 -SRPIFKNYIEANHIEVSQKELeEVEITEEDEEKILELAKDPWIREKIIASIAPSIYGHWEIKEAIALLLFGGVPKVLPD 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 327 GTRLRGDINVLLIGDPSVAKSQLLRYVLNTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEF 406
Cdd:NF040949 318 GTRIRGDIHVLIVGDPGTAKSQLLQYVARLAPRAVYTSGKGSTAAGLTAAVVRDKLTGEYYLEAGALVLADGGVAVIDEI 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 407 DKMSDIDRTAIHEVMEQGRVTISKAGIHASLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFVMLDVIDS 486
Cdd:NF040949 398 DKMREEDRSAIHEAMEQQTVSIAKAGIVATLNARASVLAAGNPKFGRYDPNRSVAENIDLPPTILSRFDLIFVIRDKPNE 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 487 DVDQMISDHVVRMHRyrnpkeadgeplsmgssyadslsfvssseekkdtevyekydallhGKSRQRHEkiLSVEFMRKYI 566
Cdd:NF040949 478 ERDRRLARHILDVHS---------------------------------------------GKEKVKPE--IDPDLLKKYI 510
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 567 HIA-KCMKPKLGEQACEAIANEYSRLRSQEAVETDVARTQPITARTLETLIRLSTAHARARMSKSVTIDDAHAAIELVQf 645
Cdd:NF040949 511 AYArKYVRPKLTEEAKKLIEDFYVEMRKSSKSSEDPDSPIPITARQLEALIRLSEAHAKMRLKDEVTAEDAERAIRLML- 589
|
....*.
gi 4903292 646 AYFKKV 651
Cdd:NF040949 590 AFLESV 595
|
|
| MCM |
cd17706 |
MCM helicase family; MCM helicases are a family of helicases that play an important role in ... |
293-646 |
4.77e-136 |
|
MCM helicase family; MCM helicases are a family of helicases that play an important role in replication and homologous recombination repair. The heterohexameric ring-shaped Mcm2-7 complex is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases. Mcm8 and Mcm9, form a complex required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350658 [Multi-domain] Cd Length: 311 Bit Score: 405.96 E-value: 4.77e-136
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 293 LLSKSLAPSIHGHAYVKQAILCLLLGGVEKILPNGTRLRGDINVLLIGDPSVAKSQLLRYVLNTAPRAIPTTGRGSSGVG 372
Cdd:cd17706 1 ILADSIAPSIYGHEDVKKAVLLQLFGGVQKILEDGTRIRGDIHILLVGDPGTAKSQILKYVLKIAPRGVYTSGKGSSGAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 373 LTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRTAIHEVMEQGRVTISKAGIHASLNARCSVLAAANPVYG 452
Cdd:cd17706 81 LTAAVVRDSETGEWYLEAGALVLADGGVCCIDEFDKMKELDRTALHEAMEQQTISIAKAGIVTTLNARCSILAAANPKGG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 453 RYDQYKTPMENIGLQDSLLSRFDLLFVMLDVIDSDVDQMISDHVVRMHRYRNPkeadgeplsmgssyadslsfvsssEEK 532
Cdd:cd17706 161 RYNPKLSPIENINLPSPLLSRFDLIFVIRDDPDEERDEELAEHIIDLHRGSDP------------------------EEQ 216
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 533 KDTEVyekydallhgksrqrHEKILSVEFMRKYIHIAKCMKPKLGEQACEAIANEYSRLRsQEAVETdvaRTQPITARTL 612
Cdd:cd17706 217 VKPEE---------------DGIPIDIELLRKYILYARQIHPKISEEAREKLVRWYVELR-KESERR---STIPITARQL 277
|
330 340 350
....*....|....*....|....*....|....
gi 4903292 613 ETLIRLSTAHARARMSKSVTIDDAHAAIELVQFA 646
Cdd:cd17706 278 ESVIRLAEAHAKMRLSEVVTEEDVEEAIRLVRHS 311
|
|
| MCM |
pfam00493 |
MCM P-loop domain; |
282-500 |
3.24e-128 |
|
MCM P-loop domain;
Pssm-ID: 459830 [Multi-domain] Cd Length: 224 Bit Score: 382.26 E-value: 3.24e-128
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 282 KKLAKNNDIFELLSKSLAPSIHGHAYVKQAILCLLLGGVEKILPNGTRLRGDINVLLIGDPSVAKSQLLRYVLNTAPRAI 361
Cdd:pfam00493 6 KELAKRPDIYDKLADSIAPSIYGHEDVKKAILLQLFGGVKKILPDGTRLRGDINVLLVGDPGTAKSQLLKYVEKIAPRAV 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 362 PTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRTAIHEVMEQGRVTISKAGIHASLNARC 441
Cdd:pfam00493 86 YTSGKGSSAAGLTAAVVRDPVTGEFVLEAGALVLADGGVCCIDEFDKMNDEDRVALHEAMEQQTISIAKAGIVATLNARC 165
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 4903292 442 SVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFVMLDVIDSDVDQMISDHVVRMH 500
Cdd:pfam00493 166 SILAAANPIFGRYDPKKSIAENINLPPPLLSRFDLIFVLLDKPDEEKDERLAKHIVDLH 224
|
|
| MCM7 |
cd17758 |
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in ... |
294-646 |
1.78e-123 |
|
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350664 [Multi-domain] Cd Length: 306 Bit Score: 373.28 E-value: 1.78e-123
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 294 LSKSLAPSIHGHAYVKQAILCLLLGGVEKIlPNGTRLRGDINVLLIGDPSVAKSQLLRYVLNTAPRAIPTTGRGSSGVGL 373
Cdd:cd17758 2 LAASIAPEIYGHEDVKKALLLLLVGGVDKR-GDGMKIRGDINICLMGDPGVAKSQLLKYICRIAPRSVYTTGRGSSGVGL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 374 TAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRTAIHEVMEQGRVTISKAGIHASLNARCSVLAAANPVYGR 453
Cdd:cd17758 81 TAAVMKDPVTGEMTLEGGALVLADQGICCIDEFDKMDESDRTAIHEVMEQQTISIAKAGITTTLNARTSILAAANPAYGR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 454 YDQYKTPMENIGLQDSLLSRFDLLFVMLDVIDSDVDQMISDHVVRMHryrnpkeadgeplsmgssyadslsfvssseekk 533
Cdd:cd17758 161 YNPRRSPEQNINLPAALLSRFDLLFLILDKPDRDNDLRLAEHVTYVH--------------------------------- 207
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 534 dtevyekydalLHGKSRQRHEKILSVEFMRKYIHIAKCMKPKLGEQACEAIANEYSRLRSQEAVETDVARTqpiTARTLE 613
Cdd:cd17758 208 -----------QHNKQPDSDFEPLDPKLLRAYIALAKRKRPTVPPALADYIVQAYVEMRQEAKRSKDFTFT---TPRTLL 273
|
330 340 350
....*....|....*....|....*....|...
gi 4903292 614 TLIRLSTAHARARMSKSVTIDDAHAAIELVQFA 646
Cdd:cd17758 274 AILRLSQALARLRLSDSVEIDDVEEALRLMEMS 306
|
|
| MCM5 |
cd17756 |
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in ... |
293-644 |
2.98e-119 |
|
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350662 [Multi-domain] Cd Length: 317 Bit Score: 362.86 E-value: 2.98e-119
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 293 LLSKSLAPSIHGHAYVKQAILCLLLGGVEKILPNGTRLRGDINVLLIGDPSVAKSQLLRYVLNTAPRAIPTTGRGSSGVG 372
Cdd:cd17756 1 IISKSIAPSIYGNEDIKKAIACLLFGGSRKRLPDGMRLRGDINVLLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 373 LTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRTAIHEVMEQGRVTISKAGIHASLNARCSVLAAANPVYG 452
Cdd:cd17756 81 LTASVMRDPSTREFYLEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRTSVLAAANPVFG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 453 RYDQYKTPMENIGLQDSLLSRFDLLFVMLDVIDSDVDQMISDHVVRMHRYRNPKeadgeplsmgssyadslsfvssseek 532
Cdd:cd17756 161 RYDDLKTPGDNIDFQTTILSRFDMIFIVKDKHDEERDITIAKHVINIHASARKA-------------------------- 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 533 kdtevyekydallhgKSRQRHEKILSVEFMRKYIHIA--KCMkPKLGEQACEAIANEYSRLRS---QEAVETDVARTQPI 607
Cdd:cd17756 215 ---------------SQSQENEGEIPISKLKRYIAYCraKCA-PRLSEEAAEKLSNHYVTIRKdvrQNELESDNRSSIPI 278
|
330 340 350
....*....|....*....|....*....|....*..
gi 4903292 608 TARTLETLIRLSTAHARARMSKSVTIDDAHAAIELVQ 644
Cdd:cd17756 279 TVRQLEAIIRISESLAKMELSPIATEKHVEEAIRLFQ 315
|
|
| MCM6 |
cd17757 |
DNA replication licensing factor Mcm6; Mcm6 is a helicase that play an important role in ... |
294-643 |
2.79e-116 |
|
DNA replication licensing factor Mcm6; Mcm6 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350663 [Multi-domain] Cd Length: 307 Bit Score: 354.75 E-value: 2.79e-116
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 294 LSKSLAPSIHGHAYVKQAILCLLLGGVEKILPNGTRLRGDINVLLIGDPSVAKSQLLRYVLNTAPRAIPTTGRGSSGVGL 373
Cdd:cd17757 2 LVRSIAPSIYGHEEVKKGILLMLLGGVHKITREGISLRGDINVCIVGDPSTAKSQFLKYVEEFSPRAVYTSGKASSAAGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 374 TAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRTAIHEVMEQGRVTISKAGIHASLNARCSVLAAANPVYGR 453
Cdd:cd17757 82 TAAVVRDEETGDFVIEAGALMLADNGICCIDEFDKMDIKDQVAIHEAMEQQTISITKAGIQATLNARTSILAAANPVGGR 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 454 YDQYKTPMENIGLQDSLLSRFDLLFVMLDVIDSDVDQMISDHVVRMHRYRNpkeadgeplsmgssyadslsfvssseekk 533
Cdd:cd17757 162 YDRSKSLKQNINISAPIMSRFDLFFVLLDECNEVTDYAIASHIVDLHSKRE----------------------------- 212
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 534 dtEVYEKYdallhgksrqrhekiLSVEFMRKYIHIAKCMKPKLGEQACEAIANEYSRLRsQEAVETDVARTQPITARTLE 613
Cdd:cd17757 213 --EAIEPP---------------FTAEQLKRYIAYARTFKPKLTKEAKDELVEQYKELR-QDDASGSTRSSYRITVRQLE 274
|
330 340 350
....*....|....*....|....*....|
gi 4903292 614 TLIRLSTAHARARMSKSVTIDDAHAAIELV 643
Cdd:cd17757 275 SLIRLSEAIARLHCSDEVTPEHVEEAARLL 304
|
|
| MCM2 |
cd17753 |
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in ... |
296-643 |
5.66e-113 |
|
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350659 [Multi-domain] Cd Length: 325 Bit Score: 346.74 E-value: 5.66e-113
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 296 KSLAPSIHGHAYVKQAILCLLLGGVEKILPNGTRLRGDINVLLIGDPSVAKSQLLRYVLNTAPRAIPTTGRGSSGVGLTA 375
Cdd:cd17753 4 NSIAPSIYGHDDIKTAIALALFGGVAKNPGGKHRIRGDINVLLLGDPGTAKSQFLKYVEKTAHRAVFTTGQGASAVGLTA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 376 AVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRTAIHEVMEQGRVTISKAGIHASLNARCSVLAAANPVYGRYD 455
Cdd:cd17753 84 SVRKDPVTKEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCSVIAAANPIGGRYN 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 456 QYKTPMENIGLQDSLLSRFDLLFVMLDVIDSDVDQMISDHVVRMHRYRNPkeadgeplsmgssyadslsfvsssEEKKDT 535
Cdd:cd17753 164 PTLTFAQNVNLTEPILSRFDILCVVRDTVDPEEDERLAKFVVGSHVRSHP------------------------ENDEDR 219
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 536 EVYEKYDAllHGKSRQRHEKILSVEFMRKYIHIAKC-MKPKLGEQACEAIANEYSRLRSqeavETDVARTQPITARTLET 614
Cdd:cd17753 220 EGEEEKNQ--RQRPKETKVEPIPQELLRKYIHYAREkVRPKLNQMDMDKVSRVYADLRK----ESMATGSLPITVRHLES 293
|
330 340
....*....|....*....|....*....
gi 4903292 615 LIRLSTAHARARMSKSVTIDDAHAAIELV 643
Cdd:cd17753 294 IIRISEAHAKMHLREYVSEEDVDMAIRVM 322
|
|
| MCM_arch |
cd17761 |
archaeal MCM protein; archaeal MCM proteins form a homohexameric ring homologous to the ... |
292-644 |
9.93e-113 |
|
archaeal MCM protein; archaeal MCM proteins form a homohexameric ring homologous to the eukaryotic Mcm2-7 helicase and also function as the replicative helicase at the replication fork
Pssm-ID: 350667 [Multi-domain] Cd Length: 308 Bit Score: 345.59 E-value: 9.93e-113
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 292 ELLSKSLAPSIHGHAYVKQAILCLLLGGVEKILPNGTRLRGDINVLLIGDPSVAKSQLLRYVLNTAPRAIPTTGRGSSGV 371
Cdd:cd17761 1 EKIISSIAPSIYGHEDVKEAIALQLFGGVPKVLPDGTRIRGDIHILLVGDPGTAKSQLLKYVSKVAPRAVYTTGKGSTAA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 372 GLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRTAIHEVMEQGRVTISKAGIHASLNARCSVLAAANPVY 451
Cdd:cd17761 81 GLTAAVVRDEGTGEWYLEAGALVLADKGIAVVDEIDKMRKEDRSALHEAMEQQTISIAKAGIVATLNARAAVLAAANPKF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 452 GRYDQYKTPMENIGLQDSLLSRFDLLFVMLDVIDSDVDQMISDHVVRMHryrnpkeadgeplsmgssYADSLSFVsssee 531
Cdd:cd17761 161 GRFDSYRPVAEQIDLPPTLLSRFDLIFVLKDTPNEEKDRRLANHILDTH------------------SGGEMREI----- 217
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 532 kkdtevyekydallhgksrqrhEKILSVEFMRKYIHIA-KCMKPKLGEQACEAIANEYSRLRSQEAvetDVARTQPITAR 610
Cdd:cd17761 218 ----------------------KPEIDPDLLRKYIAYArKNVRPVLTEEAKQLIKDFYVEMRKSGQ---ETPSPVPITAR 272
|
330 340 350
....*....|....*....|....*....|....
gi 4903292 611 TLETLIRLSTAHARARMSKSVTIDDAHAAIELVQ 644
Cdd:cd17761 273 QLEALVRLSEASARMRLSQEVTLEDAERAIRIML 306
|
|
| MCM4 |
cd17755 |
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in ... |
293-646 |
8.57e-103 |
|
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350661 [Multi-domain] Cd Length: 309 Bit Score: 319.77 E-value: 8.57e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 293 LLSKSLAPSIHGHAYVKQAILCLLLGGVEKILPN-GTRLRGDINVLLIGDPSVAKSQLLRYVLNTAPRAIPTTGRGSSGV 371
Cdd:cd17755 1 RLARSIAPSIYELEDVKKGILLQLFGGTRKDFTKtGGKYRGDINILLCGDPGTSKSQLLQYVHKISPRGVYTSGKGSSAV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 372 GLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRTAIHEVMEQGRVTISKAGIHASLNARCSVLAAANPVY 451
Cdd:cd17755 81 GLTAYVTRDPDTKQLVLESGALVLSDGGICCIDEFDKMSDSTRSVLHEVMEQQTLSIAKAGIITTLNARTSILASANPIG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 452 GRYDQYKTPMENIGLQDSLLSRFDLLFVMLDVIDSDVDQMISDHVVRMHryrnpkeadgeplsmgssyadslsfVSSSEE 531
Cdd:cd17755 161 SRYNPKLTVVENIDLPPTLLSRFDLIYLVLDKVDEKYDRRLAKHLVSLY-------------------------LEDTPE 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 532 KKDTEVyekydallhgksrqrhekiLSVEFMRKYIHIAKC-MKPKLGEQACEAIANEYSRLRSqeaVETDVARTQPITAR 610
Cdd:cd17755 216 HIQDEV-------------------LDVEVLTDYISYAREhIHPKLSEEAAQELVQAYVDMRK---MGSDARKRITATPR 273
|
330 340 350
....*....|....*....|....*....|....*.
gi 4903292 611 TLETLIRLSTAHARARMSKSVTIDDAHAAIELVQFA 646
Cdd:cd17755 274 QLESLIRLAEAHAKMRLSNVVEAEDVEEAVRLIREA 309
|
|
| PTZ00111 |
PTZ00111 |
DNA replication licensing factor MCM4; Provisional |
109-653 |
3.65e-83 |
|
DNA replication licensing factor MCM4; Provisional
Pssm-ID: 173403 [Multi-domain] Cd Length: 915 Bit Score: 285.35 E-value: 3.65e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 109 TPRSLTSIYLGNMVCVEGIVTKVSLIRPKVVRSVHYCPNTRKVMERKYTDLTS--FEAVPSGAAYP----TKDEDGNLLE 182
Cdd:PTZ00111 217 CVGNLEPSMADSLVQFSGTVVRQTWIVPEITMACFRCRGQKKIGLNDYQPCTCehYEYVIQGEVNEpllcNECNSKYTFE 296
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 183 TEYGLSVYKDHQTLTIQEMPEKAPAGQLP--------------------RSVDIVCDDDLVDRCKPGDRVQIVGSYRCLP 242
Cdd:PTZ00111 297 LNHNMCVYSTKKIVKLLQSNSSLNNPDKDgldnsvdnsglngeiymkdnEVINLNLYDDLIDSVKTGDRVTVVGILKVTP 376
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 243 gKRGGYTSGTFRT------------VLLANNISLLSK------ESNlDISREDIMLCKKLAKNNDIFELLSKSLAPSIHG 304
Cdd:PTZ00111 377 -IRTSTTRRTLKSlytyfvnvihvkVINSTNANQPEKglkylgNEN-DFSDLQVYKILELSRNPMIYRILLDSFAPSIKA 454
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 305 HAYVKQAILCLLLGGVE-----KILPNGT----RLRGDINVLLIGDPSVAKSQLLRYVLNTAPRAIPTTGRGSSGVGLTA 375
Cdd:PTZ00111 455 RNNVKIGLLCQLFSGNKnssdfNKSPDACykvdNFRGIINVLLCGDPGTAKSQLLHYTHLLSPRSIYTSGKSSSSVGLTA 534
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 376 AVT-TDQETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRTAIHEVMEQGRVTISKAGIHASLNARCSVLAAANPVYGRY 454
Cdd:PTZ00111 535 SIKfNESDNGRAMIQPGAVVLANGGVCCIDELDKCHNESRLSLYEVMEQQTVTIAKAGIVATLKAETAILASCNPINSRY 614
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 455 DQYKTPMENIGLQDSLLSRFDLLFVMLDVIDSDVDQMISDHVVRmhRYRNPKEADGEplSMGSSYADSLSFVSSSEEKKD 534
Cdd:PTZ00111 615 NKNKAVIENINISPSLFTRFDLIYLVLDHIDQDTDQLISLSIAK--DFLLPHMTGSG--NDEDTYDRSNTMHVEDESLRS 690
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 535 TEVYEKYDallhgksrqrhekilsVEFMRKYIHIAK--CMkPKLGEQACEAIANEYSRLR--------------SQEAVE 598
Cdd:PTZ00111 691 EKDYNKND----------------LDMLRMYIKFSKlhCF-PKLSDEAKKVITREYVKMRqgnfqtsnldelehAQEDDD 753
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 4903292 599 TDV------ARTQPITARTLETLIRLSTAHARARMSKSVTIDDAHAAIELVQFAYFKKVLD 653
Cdd:PTZ00111 754 DDLyyqssgTRMIYVSSRMISSIIRISVSLARMRLSTVVTPADALQAVQIVKSSTFQSLVD 814
|
|
| MCM9 |
cd17760 |
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a ... |
293-644 |
8.18e-72 |
|
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a complex with Mcm8 that is required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350666 [Multi-domain] Cd Length: 299 Bit Score: 237.44 E-value: 8.18e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 293 LLSKSLAPSIHGHAYVKQAILCLLLGGVEKILPNGTRLRGDINVLLIGDPSVAKSQLLRYVLNTAPRAIPTTGRGSSGVG 372
Cdd:cd17760 1 EILASLCPQVFGLYNVKLAVAMVLAGGVQRIDASGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTAGIGSTSAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 373 LTaaVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRTAIHEVMEQGRVTISKAGIHASLNARCSVLAAANPvYG 452
Cdd:cd17760 81 LT--VTAVKDGGEWNLEAGALVLADGGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNP-KG 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 453 RYDQYKTPMENIGLQDSLLSRFDLLFVMLDVIDSDVDQMISDHVVrmhryrnpkEADGEPlsmgssyadslsfvssseek 532
Cdd:cd17760 158 QYDPNESISVNIALASPLLSRFDLVLVLLDTKNEDWDRIISSFIL---------ENKGEP-------------------- 208
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 533 kdtevyekydallhgksrQRHEKILSVEFMRKYIHIAKCMKPKLGEQAcEAIANEYSRLRSQeAVETDVARTqpiTARTL 612
Cdd:cd17760 209 ------------------SKSSKLWSMEKMRTYFCLIKNLRPVLSDEA-NAILLRYYQLQRQ-SDCRNAART---TIRML 265
|
330 340 350
....*....|....*....|....*....|..
gi 4903292 613 ETLIRLSTAHARARMSKSVTIDDAHAAIELVQ 644
Cdd:cd17760 266 ESLIRLAEAHARLMFRETVTEEDAITVVSVME 297
|
|
| MCM8 |
cd17759 |
DNA helicase Mcm8; Mcm8 plays an important role homologous recombination repair. It forms a ... |
293-642 |
9.93e-69 |
|
DNA helicase Mcm8; Mcm8 plays an important role homologous recombination repair. It forms a complex with Mcm9 that is required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350665 [Multi-domain] Cd Length: 289 Bit Score: 228.96 E-value: 9.93e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 293 LLSKSLAPSIHGHAYVKQAILCLLLGGVEKILPNGTR--LRGDINVLLIGDPSVAKSQLLRYVLNTAPRAIPTTGRGSSG 370
Cdd:cd17759 1 LIVNSLCPAIYGHELVKAGLLLSLFGGKQKYADDKNRipIRGDPHVLIVGDPGLGKSQMLQAACNIAPRGVYVCGNTTTT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 371 VGLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDiDRTAIHEVMEQGRVTISKAGIHASLNARCSVLAAANPV 450
Cdd:cd17759 81 SGLTVTLTKDGRSGDFALEAGALVLGDQGICGIDEFDKMGS-QHQALLEAMEQQSVSLAKAGVVCSLPARTSVIAAANPV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 451 YGRYDQYKTPMENIGLQDSLLSRFDLLFVMLDVIDSDVDQMISDHVVRMHRYrnpkeadgeplsmgSSYAdslsfvssse 530
Cdd:cd17759 160 GGHYNKGKTVSENLKMGPALLSRFDLVFILLDTPSEEHDHLLSEHHQLLRKY--------------ISYA---------- 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 531 ekkdtevyekydallhgksrqrhekilsvefmRKYIHiakcmkPKLGEQACEAIANEYSRLRSQeaveTDVARTQPITAR 610
Cdd:cd17759 216 --------------------------------RQYVN------PVLSKDASEALQEFYLELRKQ----NQLADSSPITTR 253
|
330 340 350
....*....|....*....|....*....|..
gi 4903292 611 TLETLIRLSTAHARARMSKSVTIDDAHAAIEL 642
Cdd:cd17759 254 QLESLIRLTEARARLELREEATKEDAEDVIEI 285
|
|
| MCM_OB |
pfam17207 |
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains ... |
111-242 |
3.14e-48 |
|
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains an insertion at the zinc binding motif.
Pssm-ID: 465381 [Multi-domain] Cd Length: 126 Bit Score: 166.50 E-value: 3.14e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 111 RSLTSIYLGNMVCVEGIVTKVSLIRPKVVRSVHYCPNTRKVMERKYTDltsfeavPSGAAYPT-KDEDGNLLETEygLSV 189
Cdd:pfam17207 3 RDLRSEHIGKLVSVSGIVTRTSEVRPKLKKATFTCRKCGHTVGVKITE-------PTKCPNPEcGNKDPFKLVHE--KSK 73
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 4903292 190 YKDHQTLTIQEMPEKAPAGQLPRSVDIVCDDDLVDRCKPGDRVQIVGSYRCLP 242
Cdd:pfam17207 74 FVDFQKIKIQESPEEVPAGELPRSLDVILDDDLVDRVKPGDRVTVTGIYRVVP 126
|
|
| MCM_lid |
pfam17855 |
MCM AAA-lid domain; This entry represents the AAA-lid domain found in MCM proteins. |
560-646 |
5.10e-21 |
|
MCM AAA-lid domain; This entry represents the AAA-lid domain found in MCM proteins.
Pssm-ID: 465534 [Multi-domain] Cd Length: 86 Bit Score: 87.98 E-value: 5.10e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 560 EFMRKYIHIAK-CMKPKLGEQACEAIANEYSRLRSQEaveTDVARTQPITARTLETLIRLSTAHARARMSKSVTIDDAHA 638
Cdd:pfam17855 1 ELLRKYIAYAReKIKPKLSEEAREKLVDAYVELRKES---TGSGSSIPITVRQLESLIRLSEAHAKMRLSEIVTEEDVEE 77
|
....*...
gi 4903292 639 AIELVQFA 646
Cdd:pfam17855 78 AIRLLKES 85
|
|
| MCM_N |
pfam14551 |
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins. |
13-101 |
3.75e-13 |
|
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins.
Pssm-ID: 464206 [Multi-domain] Cd Length: 95 Bit Score: 65.78 E-value: 3.75e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 13 QREYVDFLD----DEEDQGIYAGHVKDMIAEKSKRLIVNVNDLKRKNPQRALGLLSNAADEQLAFGRALKEYASTV--DP 86
Cdd:pfam14551 1 KRKFKDFLEefreDGDGEFKYRDQLREMIEREQRSLEVDLDDLREFDPDLAEALLENPYEYLPLFEEALKEVVKELseDP 80
|
90
....*....|....*
gi 4903292 87 GYAKMHEDLFVGFEG 101
Cdd:pfam14551 81 DYAEEEKEFQVRFYN 95
|
|
| MoxR |
COG0714 |
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway ... |
308-482 |
1.57e-05 |
|
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis
Pssm-ID: 440478 [Multi-domain] Cd Length: 292 Bit Score: 47.47 E-value: 1.57e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 308 VKQAILCLLLGGvekilpngtrlrgdiNVLLIGDPSVAKSQLLR---YVLNTAPRAIPTTgrgssgVGLTAA-VT----T 379
Cdd:COG0714 21 IELVLIALLAGG---------------HLLLEGVPGVGKTTLAKalaRALGLPFIRIQFT------PDLLPSdILgtyiY 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 380 DQETGERRLEAGAmVLAdrGVVCIDEfdkmsdIDRT------AIHEVMEQGRVTIskAGIHASLNARCSVLAAANPVygr 453
Cdd:COG0714 80 DQQTGEFEFRPGP-LFA--NVLLADE------INRAppktqsALLEAMEERQVTI--PGGTYKLPEPFLVIATQNPI--- 145
|
170 180 190
....*....|....*....|....*....|..
gi 4903292 454 ydqyktpmENIG---LQDSLLSRFdLLFVMLD 482
Cdd:COG0714 146 --------EQEGtypLPEAQLDRF-LLKLYIG 168
|
|
| Mg_chelatase |
pfam01078 |
Magnesium chelatase, subunit ChlI; Magnesium-chelatase is a three-component enzyme that ... |
391-449 |
4.42e-05 |
|
Magnesium chelatase, subunit ChlI; Magnesium-chelatase is a three-component enzyme that catalyzes the insertion of Mg2+ into protoporphyrin IX. This is the first unique step in the synthesis of (bacterio)chlorophyll. Due to this, it is thought that Mg-chelatase has an important role in channelling inter- mediates into the (bacterio)chlorophyll branch in response to conditions suitable for photosynthetic growth. ChlI and BchD have molecular weight between 38-42 kDa.
Pssm-ID: 426032 [Multi-domain] Cd Length: 207 Bit Score: 45.22 E-value: 4.42e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 4903292 391 GAMVLADRGVVCIDEfdkMSDIDRTAI---HEVMEQGRVTISKAGIHASLNARCSVLAAANP 449
Cdd:pfam01078 100 GEISLAHNGVLFLDE---LPEFKRRVLeslRQPLEDGEITISRARAKVTFPARFQLVAAMNP 158
|
|
| AAA_5 |
pfam07728 |
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ... |
335-474 |
1.74e-04 |
|
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Pssm-ID: 400191 [Multi-domain] Cd Length: 135 Bit Score: 42.28 E-value: 1.74e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 335 NVLLIGDPSVAKSQLLRYVLntapRAIptTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADR---------GVVCIDE 405
Cdd:pfam07728 1 GVLLVGPPGTGKTELAERLA----AAL--SNRPVFYVQLTRDTTEEDLFGRRNIDPGGASWVDGplvraaregEIAVLDE 74
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 4903292 406 FDKMSDIDRTAIHEVMEQGRVTISKAG--IHASLNARcSVLAAANPVYGRydqyktPMEnigLQDSLLSRF 474
Cdd:pfam07728 75 INRANPDVLNSLLSLLDERRLLLPDGGelVKAAPDGF-RLIATMNPLDRG------LNE---LSPALRSRF 135
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
335-480 |
5.63e-04 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 40.98 E-value: 5.63e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4903292 335 NVLLIGDPSVAKSQLLRYVLNTAPRaipttgRGSSGVGLTAAVTT-------DQETGERRLEAGAMVLADRGVVCIDEFD 407
Cdd:cd00009 21 NLLLYGPPGTGKTTLARAIANELFR------PGAPFLYLNASDLLeglvvaeLFGHFLVRLLFELAEKAKPGVLFIDEID 94
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 4903292 408 KMSDIDRTAIHEVMEQGRVTISKagihaslNARCSVLAAANpvygrydqyktPMENIGLQDSLLSRFDLLFVM 480
Cdd:cd00009 95 SLSRGAQNALLRVLETLNDLRID-------RENVRVIGATN-----------RPLLGDLDRALYDRLDIRIVI 149
|
|
| YifB |
COG0606 |
Predicted Mg-chelatase, contains ChlI-like and ATPase domains, YifB family [Posttranslational ... |
391-449 |
4.22e-03 |
|
Predicted Mg-chelatase, contains ChlI-like and ATPase domains, YifB family [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440371 [Multi-domain] Cd Length: 502 Bit Score: 40.41 E-value: 4.22e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 4903292 391 GAMVLADRGVVCIDEfdkMSDIDRTAIhEV----MEQGRVTISKAGIHASLNARCSVLAAANP 449
Cdd:COG0606 290 GEISLAHNGVLFLDE---LPEFSRRVL-EAlrqpLEDGEVTISRANGSVTYPARFQLVAAMNP 348
|
|
| |
