|
Name |
Accession |
Description |
Interval |
E-value |
| PLN03226 |
PLN03226 |
serine hydroxymethyltransferase; Provisional |
79-536 |
0e+00 |
|
serine hydroxymethyltransferase; Provisional
Pssm-ID: 215639 Cd Length: 475 Bit Score: 785.71 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 79 TPLAQGDPELAELIKKEKERQREGLEMIASENFTSVAVLESLSSCLTNKYSEGYPGKRYYGGNEYIDRIELLAQQRGREL 158
Cdd:PLN03226 13 APLEEVDPEIADIIEKEKRRQWKGLELIASENFTSRAVMEALGSCLTNKYSEGLPGARYYGGNEYIDQIETLCQKRALEA 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 159 FNLDDEKWGVNVQPYSGSPANLAVYTGVCRPHDRIMGLDLPDGGHLTHGFFTPTKKISATSIFFESMPYKVNPETGIIDY 238
Cdd:PLN03226 93 FRLDPEKWGVNVQPLSGSPANFAVYTALLQPHDRIMGLDLPHGGHLSHGYQTDGKKISATSIYFESMPYRLDESTGLIDY 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 239 DKLAEAAKNFRPQIIIAGISCYSRLLDYARFRQICDDVGAYLMADMAHVAGIVAAGLIPSPFEWADIVTTTTHKTLRGPR 318
Cdd:PLN03226 173 DKLEKKAMLFRPKLIIAGASAYPRDWDYARMRKIADKVGALLMCDMAHISGLVAAQEAASPFEYCDVVTTTTHKSLRGPR 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 319 AGVIFFRKGVRSTKANGDKVLYDLEERINQAVFPSLQGGPHNNAVAGIATAFKQAKSPEFKAYQTQVLKNAKALCDGLIS 398
Cdd:PLN03226 253 GGMIFFRKGPKPPKGQGEGAVYDYEDKINFAVFPGLQGGPHNHTIAALAVALKQAMTPEFKAYQKQVKANAAALANRLMS 332
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 399 RGYQVATGGTDVHLVLVDVRKAGLTGAKAEYILEEVGIACNKNTVPGDKSAMNPSGIRLGTPALTTRGLAEQDIEQVVAF 478
Cdd:PLN03226 333 KGYKLVTGGTDNHLVLWDLRPLGLTGSRVEKVLDLAHITLNKNAVPGDSSALVPGGVRIGTPAMTSRGLVEKDFEKVAEF 412
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*...
gi 7290652 479 IDAALKVGVQAAKLAGsPKITDYHKTLAENVELKaQVDEIRKNVAQFSRKFPLPGLET 536
Cdd:PLN03226 413 LHRAVTIALKIQKEHG-KKLKDFKKGLESNDFSK-DIEALRAEVEEFATSFPMPGFDK 468
|
|
| SHMT |
pfam00464 |
Serine hydroxymethyltransferase; |
81-479 |
0e+00 |
|
Serine hydroxymethyltransferase;
Pssm-ID: 395372 Cd Length: 399 Bit Score: 709.98 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 81 LAQGDPELAELIKKEKERQREGLEMIASENFTSVAVLESLSSCLTNKYSEGYPGKRYYGGNEYIDRIELLAQQRGRELFN 160
Cdd:pfam00464 1 LEDSDPEVFDIIKKEKERQREGIELIASENFTSRAVMEALGSVLTNKYSEGYPGKRYYGGCEHVDEIETLCQDRALEAFG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 161 LDDEKWGVNVQPYSGSPANLAVYTGVCRPHDRIMGLDLPDGGHLTHGFFTPTKKISATSIFFESMPYKVNPETGIIDYDK 240
Cdd:pfam00464 81 LDPAKWGVNVQPLSGSPANLAVYTALLEPGDRIMGLDLPHGGHLTHGYPVNSKKISASSKFFESMPYGVDPETGYIDYDQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 241 LAEAAKNFRPQIIIAGISCYSRLLDYARFRQICDDVGAYLMADMAHVAGIVAAGLIPSPFEWADIVTTTTHKTLRGPRAG 320
Cdd:pfam00464 161 LEKNAKLFRPKLIVAGTSAYSRLIDYARFREIADEVGAYLMVDMAHISGLVAAGVIPSPFPYADVVTTTTHKTLRGPRGG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 321 VIFFRKGVRSTKANGDKVLYDLEERINQAVFPSLQGGPHNNAVAGIATAFKQAKSPEFKAYQTQVLKNAKALCDGLISRG 400
Cdd:pfam00464 241 MIFYRKGVKSVDKTGKEILYELEKKINSAVFPGLQGGPHNHVIAAKAVALKQALTPEFKEYQQQVVKNAKALAEALTERG 320
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 7290652 401 YQVATGGTDVHLVLVDVRKAGLTGAKAEYILEEVGIACNKNTVPGDKSAMNPSGIRLGTPALTTRGLAEQDIEQVVAFI 479
Cdd:pfam00464 321 YKLVSGGTDNHLVLVDLRPKGLDGARAEKVLEAANITANKNTIPGDKSAFVPSGLRLGTPALTSRGFGEADFEKVAGFI 399
|
|
| SHMT |
cd00378 |
Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate ... |
82-493 |
0e+00 |
|
Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl group of N5, N10-methylene tetrahydrofolate to glycine resulting in the formation of serine and tetrahydrofolate. Both eukaryotic and prokaryotic SHMT enzymes form tight obligate homodimers; the mammalian enzyme forms a homotetramer comprising four pyridoxal phosphate-bound active sites.
Pssm-ID: 99733 Cd Length: 402 Bit Score: 666.98 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 82 AQGDPELAELIKKEKERQREGLEMIASENFTSVAVLESLSSCLTNKYSEGYPGKRYYGGNEYIDRIELLAQQRGRELFNL 161
Cdd:cd00378 1 ADVDPEIAEIIKKENERQRETLELIASENFTSPAVMEAMGSDLTNKYAEGYPGKRYYGGCEYVDEIEDLAIERAKKLFGA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 162 DdekwGVNVQPYSGSPANLAVYTGVCRPHDRIMGLDLPDGGHLTHGFFTptkKISATSIFFESMPYKVNPETGIIDYDKL 241
Cdd:cd00378 81 E----YANVQPHSGSQANLAVYFALLEPGDTIMGLDLSHGGHLTHGSFT---KVSASGKLFESVPYGVDPETGLIDYDAL 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 242 AEAAKNFRPQIIIAGISCYSRLLDYARFRQICDDVGAYLMADMAHVAGIVAAGLIPSPFEWADIVTTTTHKTLRGPRAGV 321
Cdd:cd00378 154 EKMALEFKPKLIVAGASAYPRPIDFKRFREIADEVGAYLLVDMAHVAGLVAGGVFPNPLPGADVVTTTTHKTLRGPRGGL 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 322 IFFRKGvrstkangdkvlyDLEERINQAVFPSLQGGPHNNAVAGIATAFKQAKSPEFKAYQTQVLKNAKALCDGLISRGY 401
Cdd:cd00378 234 ILTRKG-------------ELAKKINSAVFPGLQGGPHLHVIAAKAVALKEALEPEFKAYAKQVVENAKALAEALKERGF 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 402 QVATGGTDVHLVLVDVRKAGLTGAKAEYILEEVGIACNKNTVPGDKS-AMNPSGIRLGTPALTTRGLAEQDIEQVVAFID 480
Cdd:cd00378 301 KVVSGGTDNHLVLVDLRPKGITGKAAEDALEEAGITVNKNTLPWDPSsPFVPSGIRIGTPAMTTRGMGEEEMEEIADFIA 380
|
410
....*....|...
gi 7290652 481 AALKVGVQAAKLA 493
Cdd:cd00378 381 RALKDAEDVAVAE 393
|
|
| GlyA |
COG0112 |
Glycine/serine hydroxymethyltransferase [Amino acid transport and metabolism]; Glycine/serine ... |
80-533 |
0e+00 |
|
Glycine/serine hydroxymethyltransferase [Amino acid transport and metabolism]; Glycine/serine hydroxymethyltransferase is part of the Pathway/BioSystem: Serine biosynthesis
Pssm-ID: 439882 Cd Length: 414 Bit Score: 635.15 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 80 PLAQGDPELAELIKKEKERQREGLEMIASENFTSVAVLESLSSCLTNKYSEGYPGKRYYGGNEYIDRIELLAQQRGRELF 159
Cdd:COG0112 4 SLAEVDPEIAEAIEKELERQEEGIELIASENFVSPAVLEAQGSVLTNKYAEGYPGKRYYGGCEYVDEVEQLAIERAKELF 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 160 NLDDekwgVNVQPYSGSPANLAVYTGVCRPHDRIMGLDLPDGGHLTHGfftptKKISATSIFFESMPYKVNPETGIIDYD 239
Cdd:COG0112 84 GAEH----ANVQPHSGSQANLAVYFALLKPGDTILGMDLAHGGHLTHG-----SPVNFSGKGYNVVSYGVDPETGLIDYD 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 240 KLAEAAKNFRPQIIIAGISCYSRLLDYARFRQICDDVGAYLMADMAHVAGIVAAGLIPSPFEWADIVTTTTHKTLRGPRA 319
Cdd:COG0112 155 EVRKLALEHKPKLIIAGASAYPRPIDFARFREIADEVGAYLMVDMAHIAGLVAGGLHPSPVPGADVVTTTTHKTLRGPRG 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 320 GVIFFRKgvrstkangdkvlyDLEERINQAVFPSLQGGPHNNAVAGIATAFKQAKSPEFKAYQTQVLKNAKALCDGLISR 399
Cdd:COG0112 235 GLILCNE--------------ELAKKIDSAVFPGLQGGPLMHVIAAKAVAFKEALTPEFKEYAKQVVKNAKALAEALAER 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 400 GYQVATGGTDVHLVLVDVRKAGLTGAKAEYILEEVGIACNKNTVPGD-KSAMNPSGIRLGTPALTTRGLAEQDIEQVVAF 478
Cdd:COG0112 301 GFRVVSGGTDNHLVLVDLRSKGLTGKEAEKALERAGITVNKNAIPFDpRSPFVTSGIRIGTPAVTTRGMKEAEMEEIAEL 380
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*
gi 7290652 479 IDAALKvgvqaaklagspkitdyhktlaeNVELKAQVDEIRKNVAQFSRKFPLPG 533
Cdd:COG0112 381 IADVLD-----------------------NPEDEAVLAEVREEVKELCKRFPLYP 412
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PLN03226 |
PLN03226 |
serine hydroxymethyltransferase; Provisional |
79-536 |
0e+00 |
|
serine hydroxymethyltransferase; Provisional
Pssm-ID: 215639 Cd Length: 475 Bit Score: 785.71 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 79 TPLAQGDPELAELIKKEKERQREGLEMIASENFTSVAVLESLSSCLTNKYSEGYPGKRYYGGNEYIDRIELLAQQRGREL 158
Cdd:PLN03226 13 APLEEVDPEIADIIEKEKRRQWKGLELIASENFTSRAVMEALGSCLTNKYSEGLPGARYYGGNEYIDQIETLCQKRALEA 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 159 FNLDDEKWGVNVQPYSGSPANLAVYTGVCRPHDRIMGLDLPDGGHLTHGFFTPTKKISATSIFFESMPYKVNPETGIIDY 238
Cdd:PLN03226 93 FRLDPEKWGVNVQPLSGSPANFAVYTALLQPHDRIMGLDLPHGGHLSHGYQTDGKKISATSIYFESMPYRLDESTGLIDY 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 239 DKLAEAAKNFRPQIIIAGISCYSRLLDYARFRQICDDVGAYLMADMAHVAGIVAAGLIPSPFEWADIVTTTTHKTLRGPR 318
Cdd:PLN03226 173 DKLEKKAMLFRPKLIIAGASAYPRDWDYARMRKIADKVGALLMCDMAHISGLVAAQEAASPFEYCDVVTTTTHKSLRGPR 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 319 AGVIFFRKGVRSTKANGDKVLYDLEERINQAVFPSLQGGPHNNAVAGIATAFKQAKSPEFKAYQTQVLKNAKALCDGLIS 398
Cdd:PLN03226 253 GGMIFFRKGPKPPKGQGEGAVYDYEDKINFAVFPGLQGGPHNHTIAALAVALKQAMTPEFKAYQKQVKANAAALANRLMS 332
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 399 RGYQVATGGTDVHLVLVDVRKAGLTGAKAEYILEEVGIACNKNTVPGDKSAMNPSGIRLGTPALTTRGLAEQDIEQVVAF 478
Cdd:PLN03226 333 KGYKLVTGGTDNHLVLWDLRPLGLTGSRVEKVLDLAHITLNKNAVPGDSSALVPGGVRIGTPAMTSRGLVEKDFEKVAEF 412
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*...
gi 7290652 479 IDAALKVGVQAAKLAGsPKITDYHKTLAENVELKaQVDEIRKNVAQFSRKFPLPGLET 536
Cdd:PLN03226 413 LHRAVTIALKIQKEHG-KKLKDFKKGLESNDFSK-DIEALRAEVEEFATSFPMPGFDK 468
|
|
| PTZ00094 |
PTZ00094 |
serine hydroxymethyltransferase; Provisional |
77-534 |
0e+00 |
|
serine hydroxymethyltransferase; Provisional
Pssm-ID: 240264 Cd Length: 452 Bit Score: 767.22 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 77 LQTPLAQGDPELAELIKKEKERQREGLEMIASENFTSVAVLESLSSCLTNKYSEGYPGKRYYGGNEYIDRIELLAQQRGR 156
Cdd:PTZ00094 11 LNQSLKEADPELYELIEKEKERQIEGLELIASENFTSRAVLECLGSCFTNKYAEGLPGNRYYGGNEVVDKIENLCQKRAL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 157 ELFNLDDEKWGVNVQPYSGSPANLAVYTGVCRPHDRIMGLDLPDGGHLTHGFFTPTKKISATSIFFESMPYKVNPEtGII 236
Cdd:PTZ00094 91 EAFGLDPEEWGVNVQPYSGSPANFAVYTALLQPHDRIMGLDLPSGGHLTHGFYTAKKKVSATSIYFESLPYQVNEK-GLI 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 237 DYDKLAEAAKNFRPQIIIAGISCYSRLLDYARFRQICDDVGAYLMADMAHVAGIVAAGLIPSPFEWADIVTTTTHKTLRG 316
Cdd:PTZ00094 170 DYDKLEELAKAFRPKLIIAGASAYPRDIDYKRFREICDSVGAYLMADIAHTSGLVAAGVLPSPFPYADVVTTTTHKSLRG 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 317 PRAGVIFFRKGVRStkangdkvlyDLEERINQAVFPSLQGGPHNNAVAGIATAFKQAKSPEFKAYQTQVLKNAKALCDGL 396
Cdd:PTZ00094 250 PRSGLIFYRKKVKP----------DIENKINEAVFPGLQGGPHNHQIAAIAVQLKEVQSPEWKEYAKQVLKNAKALAAAL 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 397 ISRGYQVATGGTDVHLVLVDVRKAGLTGAKAEYILEEVGIACNKNTVPGDKSAMNPSGIRLGTPALTTRGLAEQDIEQVV 476
Cdd:PTZ00094 320 EKRGYDLVTGGTDNHLVLVDLRPFGITGSKMEKLLDAVNISVNKNTIPGDKSALNPSGVRLGTPALTTRGAKEKDFKFVA 399
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*...
gi 7290652 477 AFIDAALKVGVQAAKLAGsPKITDYHKTLAENVELKaqvdEIRKNVAQFSRKFPLPGL 534
Cdd:PTZ00094 400 DFLDRAVKLAQEIQKQVG-KKLVDFKKALEKNPELQ----KLRQEVVEFASQFPFPGI 452
|
|
| SHMT |
pfam00464 |
Serine hydroxymethyltransferase; |
81-479 |
0e+00 |
|
Serine hydroxymethyltransferase;
Pssm-ID: 395372 Cd Length: 399 Bit Score: 709.98 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 81 LAQGDPELAELIKKEKERQREGLEMIASENFTSVAVLESLSSCLTNKYSEGYPGKRYYGGNEYIDRIELLAQQRGRELFN 160
Cdd:pfam00464 1 LEDSDPEVFDIIKKEKERQREGIELIASENFTSRAVMEALGSVLTNKYSEGYPGKRYYGGCEHVDEIETLCQDRALEAFG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 161 LDDEKWGVNVQPYSGSPANLAVYTGVCRPHDRIMGLDLPDGGHLTHGFFTPTKKISATSIFFESMPYKVNPETGIIDYDK 240
Cdd:pfam00464 81 LDPAKWGVNVQPLSGSPANLAVYTALLEPGDRIMGLDLPHGGHLTHGYPVNSKKISASSKFFESMPYGVDPETGYIDYDQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 241 LAEAAKNFRPQIIIAGISCYSRLLDYARFRQICDDVGAYLMADMAHVAGIVAAGLIPSPFEWADIVTTTTHKTLRGPRAG 320
Cdd:pfam00464 161 LEKNAKLFRPKLIVAGTSAYSRLIDYARFREIADEVGAYLMVDMAHISGLVAAGVIPSPFPYADVVTTTTHKTLRGPRGG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 321 VIFFRKGVRSTKANGDKVLYDLEERINQAVFPSLQGGPHNNAVAGIATAFKQAKSPEFKAYQTQVLKNAKALCDGLISRG 400
Cdd:pfam00464 241 MIFYRKGVKSVDKTGKEILYELEKKINSAVFPGLQGGPHNHVIAAKAVALKQALTPEFKEYQQQVVKNAKALAEALTERG 320
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 7290652 401 YQVATGGTDVHLVLVDVRKAGLTGAKAEYILEEVGIACNKNTVPGDKSAMNPSGIRLGTPALTTRGLAEQDIEQVVAFI 479
Cdd:pfam00464 321 YKLVSGGTDNHLVLVDLRPKGLDGARAEKVLEAANITANKNTIPGDKSAFVPSGLRLGTPALTSRGFGEADFEKVAGFI 399
|
|
| SHMT |
cd00378 |
Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate ... |
82-493 |
0e+00 |
|
Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl group of N5, N10-methylene tetrahydrofolate to glycine resulting in the formation of serine and tetrahydrofolate. Both eukaryotic and prokaryotic SHMT enzymes form tight obligate homodimers; the mammalian enzyme forms a homotetramer comprising four pyridoxal phosphate-bound active sites.
Pssm-ID: 99733 Cd Length: 402 Bit Score: 666.98 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 82 AQGDPELAELIKKEKERQREGLEMIASENFTSVAVLESLSSCLTNKYSEGYPGKRYYGGNEYIDRIELLAQQRGRELFNL 161
Cdd:cd00378 1 ADVDPEIAEIIKKENERQRETLELIASENFTSPAVMEAMGSDLTNKYAEGYPGKRYYGGCEYVDEIEDLAIERAKKLFGA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 162 DdekwGVNVQPYSGSPANLAVYTGVCRPHDRIMGLDLPDGGHLTHGFFTptkKISATSIFFESMPYKVNPETGIIDYDKL 241
Cdd:cd00378 81 E----YANVQPHSGSQANLAVYFALLEPGDTIMGLDLSHGGHLTHGSFT---KVSASGKLFESVPYGVDPETGLIDYDAL 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 242 AEAAKNFRPQIIIAGISCYSRLLDYARFRQICDDVGAYLMADMAHVAGIVAAGLIPSPFEWADIVTTTTHKTLRGPRAGV 321
Cdd:cd00378 154 EKMALEFKPKLIVAGASAYPRPIDFKRFREIADEVGAYLLVDMAHVAGLVAGGVFPNPLPGADVVTTTTHKTLRGPRGGL 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 322 IFFRKGvrstkangdkvlyDLEERINQAVFPSLQGGPHNNAVAGIATAFKQAKSPEFKAYQTQVLKNAKALCDGLISRGY 401
Cdd:cd00378 234 ILTRKG-------------ELAKKINSAVFPGLQGGPHLHVIAAKAVALKEALEPEFKAYAKQVVENAKALAEALKERGF 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 402 QVATGGTDVHLVLVDVRKAGLTGAKAEYILEEVGIACNKNTVPGDKS-AMNPSGIRLGTPALTTRGLAEQDIEQVVAFID 480
Cdd:cd00378 301 KVVSGGTDNHLVLVDLRPKGITGKAAEDALEEAGITVNKNTLPWDPSsPFVPSGIRIGTPAMTTRGMGEEEMEEIADFIA 380
|
410
....*....|...
gi 7290652 481 AALKVGVQAAKLA 493
Cdd:cd00378 381 RALKDAEDVAVAE 393
|
|
| GlyA |
COG0112 |
Glycine/serine hydroxymethyltransferase [Amino acid transport and metabolism]; Glycine/serine ... |
80-533 |
0e+00 |
|
Glycine/serine hydroxymethyltransferase [Amino acid transport and metabolism]; Glycine/serine hydroxymethyltransferase is part of the Pathway/BioSystem: Serine biosynthesis
Pssm-ID: 439882 Cd Length: 414 Bit Score: 635.15 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 80 PLAQGDPELAELIKKEKERQREGLEMIASENFTSVAVLESLSSCLTNKYSEGYPGKRYYGGNEYIDRIELLAQQRGRELF 159
Cdd:COG0112 4 SLAEVDPEIAEAIEKELERQEEGIELIASENFVSPAVLEAQGSVLTNKYAEGYPGKRYYGGCEYVDEVEQLAIERAKELF 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 160 NLDDekwgVNVQPYSGSPANLAVYTGVCRPHDRIMGLDLPDGGHLTHGfftptKKISATSIFFESMPYKVNPETGIIDYD 239
Cdd:COG0112 84 GAEH----ANVQPHSGSQANLAVYFALLKPGDTILGMDLAHGGHLTHG-----SPVNFSGKGYNVVSYGVDPETGLIDYD 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 240 KLAEAAKNFRPQIIIAGISCYSRLLDYARFRQICDDVGAYLMADMAHVAGIVAAGLIPSPFEWADIVTTTTHKTLRGPRA 319
Cdd:COG0112 155 EVRKLALEHKPKLIIAGASAYPRPIDFARFREIADEVGAYLMVDMAHIAGLVAGGLHPSPVPGADVVTTTTHKTLRGPRG 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 320 GVIFFRKgvrstkangdkvlyDLEERINQAVFPSLQGGPHNNAVAGIATAFKQAKSPEFKAYQTQVLKNAKALCDGLISR 399
Cdd:COG0112 235 GLILCNE--------------ELAKKIDSAVFPGLQGGPLMHVIAAKAVAFKEALTPEFKEYAKQVVKNAKALAEALAER 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 400 GYQVATGGTDVHLVLVDVRKAGLTGAKAEYILEEVGIACNKNTVPGD-KSAMNPSGIRLGTPALTTRGLAEQDIEQVVAF 478
Cdd:COG0112 301 GFRVVSGGTDNHLVLVDLRSKGLTGKEAEKALERAGITVNKNAIPFDpRSPFVTSGIRIGTPAVTTRGMKEAEMEEIAEL 380
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*
gi 7290652 479 IDAALKvgvqaaklagspkitdyhktlaeNVELKAQVDEIRKNVAQFSRKFPLPG 533
Cdd:COG0112 381 IADVLD-----------------------NPEDEAVLAEVREEVKELCKRFPLYP 412
|
|
| glyA |
PRK00011 |
serine hydroxymethyltransferase; Reviewed |
80-533 |
0e+00 |
|
serine hydroxymethyltransferase; Reviewed
Pssm-ID: 234571 Cd Length: 416 Bit Score: 619.01 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 80 PLAQGDPELAELIKKEKERQREGLEMIASENFTSVAVLESLSSCLTNKYSEGYPGKRYYGGNEYIDRIELLAQQRGRELF 159
Cdd:PRK00011 5 NLAEYDPEIADAIEQELKRQEEHIELIASENFVSPAVMEAQGSVLTNKYAEGYPGKRYYGGCEYVDVVEQLAIDRAKELF 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 160 NLDDekwgVNVQPYSGSPANLAVYTGVCRPHDRIMGLDLPDGGHLTHGfftptKKISATSIFFESMPYKVNPETGIIDYD 239
Cdd:PRK00011 85 GAEY----ANVQPHSGSQANAAVYFALLKPGDTILGMDLAHGGHLTHG-----SPVNFSGKLYNVVSYGVDEETGLIDYD 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 240 KLAEAAKNFRPQIIIAGISCYSRLLDYARFRQICDDVGAYLMADMAHVAGIVAAGLIPSPFEWADIVTTTTHKTLRGPRA 319
Cdd:PRK00011 156 EVEKLALEHKPKLIIAGASAYSRPIDFKRFREIADEVGAYLMVDMAHIAGLVAAGVHPSPVPHADVVTTTTHKTLRGPRG 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 320 GVIFFRKGvrstkangdkvlyDLEERINQAVFPSLQGGPHNNAVAGIATAFKQAKSPEFKAYQTQVLKNAKALCDGLISR 399
Cdd:PRK00011 236 GLILTNDE-------------ELAKKINSAVFPGIQGGPLMHVIAAKAVAFKEALEPEFKEYAQQVVKNAKALAEALAER 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 400 GYQVATGGTDVHLVLVDVRKAGLTGAKAEYILEEVGIACNKNTVPGD-KSAMNPSGIRLGTPALTTRGLAEQDIEQVVAF 478
Cdd:PRK00011 303 GFRVVSGGTDNHLVLVDLRSKGLTGKEAEAALEEANITVNKNAVPFDpRSPFVTSGIRIGTPAITTRGFKEAEMKEIAEL 382
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*
gi 7290652 479 IDAALKvgvqaaklagspkitdyhktlaeNVELKAQVDEIRKNVAQFSRKFPLPG 533
Cdd:PRK00011 383 IADVLD-----------------------NPDDEAVIEEVKEEVKELCKRFPLYK 414
|
|
| PLN02271 |
PLN02271 |
serine hydroxymethyltransferase |
80-535 |
0e+00 |
|
serine hydroxymethyltransferase
Pssm-ID: 215153 Cd Length: 586 Bit Score: 564.04 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 80 PLAQGDPELAELIKKEKERQREGLEMIASENFTSVAVLESLSSCLTNKYSEGYPGKRYYGGNEYIDRIELLAQQRGRELF 159
Cdd:PLN02271 128 PLPEADPDIHELMEKEKQRQFKGIELIASENFVCRAVMEALGSHLTNKYSEGMPGARYYTGNQYIDQIERLCCERALAAF 207
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 160 NLDDEKWGVNVQPYSGSPANLAVYTGVCRPHDRIMGLDLPDGGHLTHGFFTPT-KKISATSIFFESMPYKVNPETGIIDY 238
Cdd:PLN02271 208 GLDSEKWGVNVQPYSCTSANFAVYTGLLLPGDRIMGLDSPSGGHMSHGYYTPGgKKVSGASIFFESLPYKVNPQTGYIDY 287
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 239 DKLAEAAKNFRPQIIIAGISCYSRLLDYARFRQICDDVGAYLMADMAHVAGIVAAGLIPSPFEWADIVTTTTHKTLRGPR 318
Cdd:PLN02271 288 DKLEEKALDFRPKILICGGSSYPREWDYARFRQIADKCGAVLMCDMAHISGLVAAKECVNPFDYCDIVTSTTHKSLRGPR 367
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 319 AGVIFFRKGVRSTKANG------DKVLYDLEERINQAVFPSLQGGPHNNAVAGIATAFKQAKSPEFKAYQTQVLKNAKAL 392
Cdd:PLN02271 368 GGIIFYRKGPKLRKQGMllshgdDNSHYDFEEKINFAVFPSLQGGPHNNHIAALAIALKQVATPEYKAYMQQVKKNAQAL 447
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 393 CDGLISRGYQVATGGTDVHLVLVDVRKAGLTGAKAEYILEEVGIACNKNTVPGDKSAMNPSGIRLGTPALTTRGLAEQDI 472
Cdd:PLN02271 448 ASALLRRKCRLVTGGTDNHLLLWDLTTLGLTGKNYEKVCEMCHITLNKTAIFGDNGTISPGGVRIGTPAMTSRGCLESDF 527
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 7290652 473 EQVVAFIDAALKVGVQAAKLAGSPKiTDYHKTLAENVElkaqVDEIRKNVAQFSRKFPLPGLE 535
Cdd:PLN02271 528 ETIADFLLRAAQIASAVQREHGKLQ-KEFLKGLQNNKD----IVELRNRVEAFASQFAMPGFD 585
|
|
| PRK13034 |
PRK13034 |
serine hydroxymethyltransferase; Reviewed |
78-532 |
0e+00 |
|
serine hydroxymethyltransferase; Reviewed
Pssm-ID: 237280 Cd Length: 416 Bit Score: 531.46 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 78 QTPLAQGDPELAELIKKEKERQREGLEMIASENFTSVAVLESLSSCLTNKYSEGYPGKRYYGGNEYIDRIELLAQQRGRE 157
Cdd:PRK13034 6 SDSLEEYDDEVFAAINKELERQQDHLELIASENFTSPAVMEAQGSVLTNKYAEGYPGKRYYGGCEFVDEVEALAIERAKQ 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 158 LFNLDdekwGVNVQPYSGSPANLAVYTGVCRPHDRIMGLDLPDGGHLTHGfftptKKISATSIFFESMPYKVNPETGIID 237
Cdd:PRK13034 86 LFGCD----YANVQPHSGSQANGAVYLALLKPGDTILGMSLSHGGHLTHG-----AKVSLSGKWYNAVQYGVDRLTGLID 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 238 YDKLAEAAKNFRPQIIIAGISCYSRLLDYARFRQICDDVGAYLMADMAHVAGIVAAGLIPSPFEWADIVTTTTHKTLRGP 317
Cdd:PRK13034 157 YDEVEELAKEHKPKLIIAGFSAYPRELDFARFREIADEVGALLMVDMAHIAGLVAAGEHPNPFPHAHVVTTTTHKTLRGP 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 318 RAGVIFfrkgvrstkANGDkvlyDLEERINQAVFPSLQGGPHNNAVAGIATAFKQAKSPEFKAYQTQVLKNAKALCDGLI 397
Cdd:PRK13034 237 RGGMIL---------TNDE----EIAKKINSAVFPGLQGGPLMHVIAAKAVAFGEALQPEFKTYAKQVIANAQALAEVLK 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 398 SRGYQVATGGTDVHLVLVDVRKAGLTGAKAEYILEEVGIACNKNTVPGD-KSAMNPSGIRLGTPALTTRGLAEQDIEQVV 476
Cdd:PRK13034 304 ERGYDLVSGGTDNHLLLVDLRPKGLSGKDAEQALERAGITVNKNTVPGDtESPFVTSGIRIGTPAGTTRGFGEAEFREIA 383
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*.
gi 7290652 477 AFIDAALkvgvqaaklagspkitdyhktlaENVELKAQVDEIRKNVAQFSRKFPLP 532
Cdd:PRK13034 384 NWILDVL-----------------------DDLGNAALEQRVRKEVKALCSRFPIY 416
|
|
| PRK13580 |
PRK13580 |
glycine hydroxymethyltransferase; |
54-535 |
3.63e-145 |
|
glycine hydroxymethyltransferase;
Pssm-ID: 184161 Cd Length: 493 Bit Score: 426.76 E-value: 3.63e-145
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 54 LPAIRRYSDSKQSTLKNMADQKLLQTpLAQGDPELAELIKKEKERQREGLEMIASENFTSVAVLESLSSCLTNKYSEGYP 133
Cdd:PRK13580 4 DKALLNASGKDQQNLASTAYLAALDV-ILHVEPRIAEAIRQELADQRSSLKLIASENYSSLAVQLAMGNLLTDKYAEGTP 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 134 GKRYYGGNEYIDRIELLAQQRGRELFNLDDekwgVNVQPYSGSPANLAVY---------------TGVCRPHD------- 191
Cdd:PRK13580 83 GHRFYAGCQNVDTVEWEAAEHAKELFGAEH----AYVQPHSGADANLVAFwailahkvespalekLGAKTVNDlteedwe 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 192 ---------RIMGLDLPDGGHLTHGFftptkKISATSIFFESMPYKVNPETGIIDYDKLAEAAKNFRPQIIIAGISCYSR 262
Cdd:PRK13580 159 alraelgnqRLLGMSLDSGGHLTHGF-----RPNISGKMFHQRSYGVDPDTGLLDYDEIAALAREFKPLILVAGYSAYPR 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 263 LLDYARFRQICDDVGAYLMADMAHVAGIVAAGLIP---SPFEWADIVTTTTHKTLRGPRAGVIFFRKgvrstkangdkvl 339
Cdd:PRK13580 234 RVNFAKLREIADEVGAVLMVDMAHFAGLVAGKVFTgdeDPVPHADIVTTTTHKTLRGPRGGLVLAKK------------- 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 340 yDLEERINQAVfPSLQGGPHNNAVAGIATAFKQAKSPEFKAYQTQVLKNAKALCDGLISRGYQVATGGTDVHLVLVDVRK 419
Cdd:PRK13580 301 -EYADAVDKGC-PLVLGGPLPHVMAAKAVALAEARTPEFQKYAQQVVDNARALAEGFLKRGARLVTGGTDNHLVLIDVTS 378
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 420 AGLTGAKAEYILEEVGIACNKNTVPGDKS-AMNPSGIRLGTPALTTRGLAEQDIEQVVAFIDAALKVGVQAAKLAGSPKI 498
Cdd:PRK13580 379 FGLTGRQAESALLDAGIVTNRNSIPSDPNgAWYTSGIRLGTPALTTLGMGSDEMDEVAELIVKVLSNTTPGTTAEGAPSK 458
|
490 500 510
....*....|....*....|....*....|....*...
gi 7290652 499 TDYhkTLAENVelkaqVDEIRKNVAQFSRKFPL-PGLE 535
Cdd:PRK13580 459 AKY--ELDEGV-----AQEVRARVAELLARFPLyPEID 489
|
|
| AAT_I |
cd01494 |
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP) ... |
151-325 |
2.13e-25 |
|
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. Structure and sequence analysis has revealed that the PLP dependent enzymes can be classified into four major groups of different evolutionary origin: aspartate aminotransferase superfamily (fold type I), tryptophan synthase beta superfamily (fold type II), alanine racemase superfamily (fold type III), and D-amino acid superfamily (fold type IV) and Glycogen phophorylase family (fold type V).
Pssm-ID: 99742 [Multi-domain] Cd Length: 170 Bit Score: 102.46 E-value: 2.13e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 151 AQQRGRELFNLDDekWGVNVQPySGSPANLAVYTGVCRPHDRIMGLDLPDGGHLTHgfftptkkiSATSIFFESMPYKVN 230
Cdd:cd01494 5 LEEKLARLLQPGN--DKAVFVP-SGTGANEAALLALLGPGDEVIVDANGHGSRYWV---------AAELAGAKPVPVPVD 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 231 PET-GIIDYDKLAEAAKNFRPQIIIAGISCYSRLL--DYARFRQICDDVGAYLMADMAHVAGIVAAGLIPSPFEWADIVT 307
Cdd:cd01494 73 DAGyGGLDVAILEELKAKPNVALIVITPNTTSGGVlvPLKEIRKIAKEYGILLLVDAASAGGASPAPGVLIPEGGADVVT 152
|
170
....*....|....*...
gi 7290652 308 TTTHKTLRGPRAGVIFFR 325
Cdd:cd01494 153 FSLHKNLGGEGGGVVIVK 170
|
|
| Aminotran_1_2 |
pfam00155 |
Aminotransferase class I and II; |
141-479 |
6.97e-06 |
|
Aminotransferase class I and II;
Pssm-ID: 395103 [Multi-domain] Cd Length: 351 Bit Score: 48.46 E-value: 6.97e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 141 NEYIDRI------ELLAQQRGRElfNLDDEKWGVNVQPYSGSPANLAVYTGVCRPHDRIMGLDLPdgghlTHGFFTPTKK 214
Cdd:pfam00155 33 NLYGPTDghpelrEALAKFLGRS--PVLKLDREAAVVFGSGAGANIEALIFLLANPGDAILVPAP-----TYASYIRIAR 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 215 ISAtsifFESMPYKVNPETGI-IDYDKLAEAAKNfRPQIIIAGiSCYS------RLLDYARFRQICDDVGAYLMADMAHV 287
Cdd:pfam00155 106 LAG----GEVVRYPLYDSNDFhLDFDALEAALKE-KPKVVLHT-SPHNptgtvaTLEELEKLLDLAKEHNILLLVDEAYA 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 288 AGI--------VAAGLIPSPfewADIVTTTTHKT--LRGPRAGVIFFRKGVRSTkangdkvlydLEERINQAVFPSLqgG 357
Cdd:pfam00155 180 GFVfgspdavaTRALLAEGP---NLLVVGSFSKAfgLAGWRVGYILGNAAVISQ----------LRKLARPFYSSTH--L 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 358 PHnnAVAGIATAFKQaKSPEFKAYQTQVLKNAKALCDGLISRGYQVATGGTdvHLVLVDVRKAGLTGAKAEYILEEVGIA 437
Cdd:pfam00155 245 QA--AAAAALSDPLL-VASELEEMRQRIKERRDYLRDGLQAAGLSVLPSQA--GFFLLTGLDPETAKELAQVLLEEVGVY 319
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 7290652 438 CNKNTVPGdksamNPSGIRLGTPALTtrglaEQDIEQVVAFI 479
Cdd:pfam00155 320 VTPGSSPG-----VPGWLRITVAGGT-----EEELEELLEAI 351
|
|
| Orn_deC_like |
cd00615 |
Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent ... |
151-351 |
6.68e-03 |
|
Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine decarboxylase (LDC). ODC is a dodecamer composed of six homodimers and catalyzes the decarboxylation of tryptophan. ADC catalyzes the decarboxylation of arginine and LDC catalyzes the decarboxylation of lysine. Members of this family are widely found in all three forms of life.
Pssm-ID: 99739 [Multi-domain] Cd Length: 294 Bit Score: 38.77 E-value: 6.68e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 151 AQQRGRELFNldDEKWGVNVQPYSGSpaNLAVYTGVCRPHDRIMgldLPDGGH--LTHGFFtptkkIS-ATSIFFESmpy 227
Cdd:cd00615 64 AQELAARAFG--AKHTFFLVNGTSSS--NKAVILAVCGPGDKIL---IDRNCHksVINGLV-----LSgAVPVYLKP--- 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7290652 228 KVNPETGI---IDYDKLAEAAKNFRP--QIIIA-----GISCysrllDYARFRQICDDVGAYLMADMAHVAGIVAAGLIP 297
Cdd:cd00615 129 ERNPYYGIaggIPPETFKKALIEHPDakAAVITnptyyGICY-----NLRKIVEEAHHRGLPVLVDEAHGAHFRFHPILP 203
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 7290652 298 S--PFEWADIVTTTTHKTLRGPRAGVIFFRKGVRstkangdkvlyDLEERINQAVF 351
Cdd:cd00615 204 SsaAMAGADIVVQSTHKTLPALTQGSMIHVKGDL-----------VNPDRVNEALN 248
|
|
| |
