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Conserved domains on  [gi|9937315|gb|AAG02413|]
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sep10p [Schizosaccharomyces pombe]

Protein Classification

mediator of RNA polymerase II transcription subunit 31( domain architecture ID 10009074)

mediator of RNA polymerase II transcription subunit 31 (Med31) is a component of the mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SOH1 COG5088
Rad5p-binding protein [General function prediction only];
1-114 2.01e-62

Rad5p-binding protein [General function prediction only];


:

Pssm-ID: 227420  Cd Length: 114  Bit Score: 186.63  E-value: 2.01e-62
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9937315    1 METKWLLSKVPDDKSRFEIELEFVQMLSNPWYLNFLAQHKYFEDEAFLQYLEYMEYWREPEYVKFIIYPTCLHMLTLLKN 80
Cdd:COG5088   1 SSTNGNAPATPSSDSRFEVELEFVQSLANPQYLTLLTQQQIFESENFKNYLKYLEYWRNPEYSQFIVYPNCLFILKLLNG 80

                        90       100       110
                ....*....|....*....|....*....|....
gi 9937315   81 PQFRNDISRADLSKQVNDEIYYEWLGKGLQQYGS 114
Cdd:COG5088  81 FMESAIVSEDGLLEGLDELQYPQWLNKMVERWAN 114
 
Name Accession Description Interval E-value
SOH1 COG5088
Rad5p-binding protein [General function prediction only];
1-114 2.01e-62

Rad5p-binding protein [General function prediction only];


Pssm-ID: 227420  Cd Length: 114  Bit Score: 186.63  E-value: 2.01e-62
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9937315    1 METKWLLSKVPDDKSRFEIELEFVQMLSNPWYLNFLAQHKYFEDEAFLQYLEYMEYWREPEYVKFIIYPTCLHMLTLLKN 80
Cdd:COG5088   1 SSTNGNAPATPSSDSRFEVELEFVQSLANPQYLTLLTQQQIFESENFKNYLKYLEYWRNPEYSQFIVYPNCLFILKLLNG 80

                        90       100       110
                ....*....|....*....|....*....|....
gi 9937315   81 PQFRNDISRADLSKQVNDEIYYEWLGKGLQQYGS 114
Cdd:COG5088  81 FMESAIVSEDGLLEGLDELQYPQWLNKMVERWAN 114
Med31 pfam05669
SOH1; The family consists of Saccharomyces cerevisiae SOH1 homologs. SOH1 is responsible for ...
 14-105 1.70e-51

SOH1; The family consists of Saccharomyces cerevisiae SOH1 homologs. SOH1 is responsible for the repression of temperature sensitive growth of the HPR1 mutant and has been found to be a component of the RNA polymerase II transcription complex. SOH1 not only interacts with factors involved in DNA repair, but transcription as well. Thus, the SOH1 protein may serve to couple these two processes.


Pssm-ID: 428575  Cd Length: 95  Bit Score: 158.45  E-value: 1.70e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9937315     14 KSRFEIELEFVQMLSNPWYLNFLAQHKYFEDEAFLQYLEYMEYWREPEYVKFIIYPTCLHMLTLLKNPQFRNDISRADLS 93
Cdd:pfam05669   1 KTRFELELEFVQSLANPQYLNHLAQNGYLEDPAFINYLKYLQYWKEPEYAKFLTYPHCLHFLDLLQNEEFRQEISNPDFA 80

                          90
                  ....*....|..
gi 9937315     94 KQVNDEIYYEWL 105
Cdd:pfam05669  81 KFLMDQQYLHWQ 92
 
Name Accession Description Interval E-value
SOH1 COG5088
Rad5p-binding protein [General function prediction only];
1-114 2.01e-62

Rad5p-binding protein [General function prediction only];


Pssm-ID: 227420  Cd Length: 114  Bit Score: 186.63  E-value: 2.01e-62
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9937315    1 METKWLLSKVPDDKSRFEIELEFVQMLSNPWYLNFLAQHKYFEDEAFLQYLEYMEYWREPEYVKFIIYPTCLHMLTLLKN 80
Cdd:COG5088   1 SSTNGNAPATPSSDSRFEVELEFVQSLANPQYLTLLTQQQIFESENFKNYLKYLEYWRNPEYSQFIVYPNCLFILKLLNG 80

                        90       100       110
                ....*....|....*....|....*....|....
gi 9937315   81 PQFRNDISRADLSKQVNDEIYYEWLGKGLQQYGS 114
Cdd:COG5088  81 FMESAIVSEDGLLEGLDELQYPQWLNKMVERWAN 114
Med31 pfam05669
SOH1; The family consists of Saccharomyces cerevisiae SOH1 homologs. SOH1 is responsible for ...
 14-105 1.70e-51

SOH1; The family consists of Saccharomyces cerevisiae SOH1 homologs. SOH1 is responsible for the repression of temperature sensitive growth of the HPR1 mutant and has been found to be a component of the RNA polymerase II transcription complex. SOH1 not only interacts with factors involved in DNA repair, but transcription as well. Thus, the SOH1 protein may serve to couple these two processes.


Pssm-ID: 428575  Cd Length: 95  Bit Score: 158.45  E-value: 1.70e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9937315     14 KSRFEIELEFVQMLSNPWYLNFLAQHKYFEDEAFLQYLEYMEYWREPEYVKFIIYPTCLHMLTLLKNPQFRNDISRADLS 93
Cdd:pfam05669   1 KTRFELELEFVQSLANPQYLNHLAQNGYLEDPAFINYLKYLQYWKEPEYAKFLTYPHCLHFLDLLQNEEFRQEISNPDFA 80

                          90
                  ....*....|..
gi 9937315     94 KQVNDEIYYEWL 105
Cdd:pfam05669  81 KFLMDQQYLHWQ 92
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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