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Conserved domains on  [gi|29179426|gb|AAH48835|]
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Flnb protein, partial [Mus musculus]

Protein Classification

filamin/ABP280 repeat-containing protein( domain architecture ID 18089955)

filamin/ABP280 repeat-containing protein may function as an actin-binding protein; similar to Drosophila melanogaster jitterbug

Gene Ontology:  GO:0003779

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 310-400 7.29e-31

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 116.16  E-value: 7.29e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29179426    310 AHKVRAGGPGLERGEAGIPAEFSIWTREAGAGGLSIAVEGPS--KAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEH 387
Cdd:smart00557   1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80

                           90
                   ....*....|...
gi 29179426    388 IPDSPYLVPVIAP 400
Cdd:smart00557  81 IPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 119-208 7.35e-28

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 107.69  E-value: 7.35e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29179426    119 ARRAKVYGQGLSEGRTFEMSDFIVDTRDAGYGGISLAVEGPS--KVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADEH 196
Cdd:smart00557   1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80

                           90
                   ....*....|..
gi 29179426    197 VPGSPFTVKISG 208
Cdd:smart00557  81 IPGSPFTVKVGP 92
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 629-718 3.23e-26

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 102.68  E-value: 3.23e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29179426    629 ASKVTSKGAGLSKAFVGQKSSFLVDCSKAGSNMLLIGVHGPTTPCEEVSMKHVGKQQYNVTYVVKERGDYVLAVKWGEEH 708
Cdd:smart00557   1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80

                           90
                   ....*....|
gi 29179426    709 IPGSPFHVTV 718
Cdd:smart00557  81 IPGSPFTVKV 90
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 501-590 4.28e-22

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 91.13  E-value: 4.28e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29179426    501 PALVSAYGAGLETGTTGIQSEFFINTTQAGPGTLSVTIEGPS--KVKMDCQEIPEG-YKVMYTPMAPGNYLIGVKYGGpN 577
Cdd:smart00557   1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkKVPVEVKDNGDGtYTVSYTPTEPGDYTVTVKFGG-E 79

                           90
                   ....*....|...
gi 29179426    578 HISRSPFKAKVTG 590
Cdd:smart00557  80 HIPGSPFTVKVGP 92
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 418-495 5.86e-21

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 87.66  E-value: 5.86e-21
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 29179426    418 KVNQPASFAIRLNGA-KGKIDAKVHSPSGAVEECHVSELEPDKYAVRFIPHENGIHTIDVKFNGSHVVGSPFKVRVGEP 495
Cdd:smart00557  15 VVGEPAEFTVDTRDAgGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 243-304 1.26e-13

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 66.86  E-value: 1.26e-13
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 29179426    243 SSDMSAHVTSPSGHVTEAEIVPMGKNSHCVRFVPQEMGVHTVSVKYRGQHVTGSPFQFTVGP 304
Cdd:smart00557  31 GGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKVGP 92
IG_FLMN super family cl42963
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 33-114 6.96e-13

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


The actual alignment was detected with superfamily member smart00557:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 64.93  E-value: 6.96e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29179426     33 SQVKLGSAADFLLDISETDLSTLTASIKAPSGRDEPCLLKRLPNNHIGISFIPREVGEHLVSIKKNGNHVANSPVSIMVV 112
Cdd:smart00557  12 EKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKVG 91


                   ..
gi 29179426    113 QS 114
Cdd:smart00557  92 PA 93
IG_FLMN super family cl42963
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 2-27 1.68e-06

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


The actual alignment was detected with superfamily member smart00557:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 46.83  E-value: 1.68e-06
                           10        20
                   ....*....|....*....|....*.
gi 29179426      2 PGDYSILVKYNDKHIPGSPFTAKITD 27
Cdd:smart00557  67 PGDYTVTVKFGGEHIPGSPFTVKVGP 92
 
Name Accession Description Interval E-value
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 310-400 7.29e-31

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 116.16  E-value: 7.29e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29179426    310 AHKVRAGGPGLERGEAGIPAEFSIWTREAGAGGLSIAVEGPS--KAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEH 387
Cdd:smart00557   1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80

                           90
                   ....*....|...
gi 29179426    388 IPDSPYLVPVIAP 400
Cdd:smart00557  81 IPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 119-208 7.35e-28

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 107.69  E-value: 7.35e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29179426    119 ARRAKVYGQGLSEGRTFEMSDFIVDTRDAGYGGISLAVEGPS--KVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADEH 196
Cdd:smart00557   1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80

                           90
                   ....*....|..
gi 29179426    197 VPGSPFTVKISG 208
Cdd:smart00557  81 IPGSPFTVKVGP 92
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 629-718 3.23e-26

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 102.68  E-value: 3.23e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29179426    629 ASKVTSKGAGLSKAFVGQKSSFLVDCSKAGSNMLLIGVHGPTTPCEEVSMKHVGKQQYNVTYVVKERGDYVLAVKWGEEH 708
Cdd:smart00557   1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80

                           90
                   ....*....|
gi 29179426    709 IPGSPFHVTV 718
Cdd:smart00557  81 IPGSPFTVKV 90
Filamin pfam00630
Filamin/ABP280 repeat;
308-393 9.29e-24

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 95.82  E-value: 9.29e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29179426   308 GGAHKVRAGGPGLERGEAGIPAEFSIWTREAGaGGLSIAVEGPS--KAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFND 385
Cdd:pfam00630   2 ADASKVKASGPGLEPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDgsPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNG 80


                  ....*...
gi 29179426   386 EHIPDSPY 393
Cdd:pfam00630  81 QHIPGSPF 88
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 501-590 4.28e-22

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 91.13  E-value: 4.28e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29179426    501 PALVSAYGAGLETGTTGIQSEFFINTTQAGPGTLSVTIEGPS--KVKMDCQEIPEG-YKVMYTPMAPGNYLIGVKYGGpN 577
Cdd:smart00557   1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkKVPVEVKDNGDGtYTVSYTPTEPGDYTVTVKFGG-E 79

                           90
                   ....*....|...
gi 29179426    578 HISRSPFKAKVTG 590
Cdd:smart00557  80 HIPGSPFTVKVGP 92
Filamin pfam00630
Filamin/ABP280 repeat;
117-203 4.55e-22

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 90.81  E-value: 4.55e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29179426   117 GDARRAKVYGQGLSEGRTFEMSDFIVDTRDAGyGGISLAVEGPS--KVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFAD 194
Cdd:pfam00630   2 ADASKVKASGPGLEPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDgsPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNG 80


                  ....*....
gi 29179426   195 EHVPGSPFT 203
Cdd:pfam00630  81 QHIPGSPFK 89
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 418-495 5.86e-21

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 87.66  E-value: 5.86e-21
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 29179426    418 KVNQPASFAIRLNGA-KGKIDAKVHSPSGAVEECHVSELEPDKYAVRFIPHENGIHTIDVKFNGSHVVGSPFKVRVGEP 495
Cdd:smart00557  15 VVGEPAEFTVDTRDAgGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKVGPA 93
Filamin pfam00630
Filamin/ABP280 repeat;
418-489 7.23e-20

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 84.65  E-value: 7.23e-20
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 29179426   418 KVNQPASFAIRLNGAKGKIDAKVHSPSGAVEECHVSELEPDKYAVRFIPHENGIHTIDVKFNGSHVVGSPFK 489
Cdd:pfam00630  18 VVGKPAEFTVDTRDAGGEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSPFK 89
Filamin pfam00630
Filamin/ABP280 repeat;
626-715 9.57e-18

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 78.48  E-value: 9.57e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29179426   626 SSDASKVTSKGAGLSKAFVGQKSSFLVDCSKAGSNmLLIGVHGPTTPCEEVSMKHVGKQQYNVTYVVKERGDYVLAVKWG 705
Cdd:pfam00630   1 AADASKVKASGPGLEPGVVGKPAEFTVDTRDAGGE-GEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFN 79

                          90
                  ....*....|
gi 29179426   706 EEHIPGSPFH 715
Cdd:pfam00630  80 GQHIPGSPFK 89
Filamin pfam00630
Filamin/ABP280 repeat;
498-585 2.67e-16

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 74.25  E-value: 2.67e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29179426   498 AGNPALVSAYGAGLETGTTGIQSEFFINTTQAGpGTLSVTIEGPSKVKMDCQEIPEG---YKVMYTPMAPGNYLIGVKYG 574
Cdd:pfam00630   1 AADASKVKASGPGLEPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDGSPVPVEVTDNGdgtYTVSYTPTEPGDYTVSVKFN 79

                          90
                  ....*....|.
gi 29179426   575 GpNHISRSPFK 585
Cdd:pfam00630  80 G-QHIPGSPFK 89
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 243-304 1.26e-13

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 66.86  E-value: 1.26e-13
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 29179426    243 SSDMSAHVTSPSGHVTEAEIVPMGKNSHCVRFVPQEMGVHTVSVKYRGQHVTGSPFQFTVGP 304
Cdd:smart00557  31 GGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKVGP 92
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 33-114 6.96e-13

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 64.93  E-value: 6.96e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29179426     33 SQVKLGSAADFLLDISETDLSTLTASIKAPSGRDEPCLLKRLPNNHIGISFIPREVGEHLVSIKKNGNHVANSPVSIMVV 112
Cdd:smart00557  12 EKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKVG 91


                   ..
gi 29179426    113 QS 114
Cdd:smart00557  92 PA 93
Filamin pfam00630
Filamin/ABP280 repeat;
249-298 9.10e-11

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 58.84  E-value: 9.10e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 29179426   249 HVTSPSGHVTEAEIVPMGKNSHCVRFVPQEMGVHTVSVKYRGQHVTGSPF 298
Cdd:pfam00630  39 EVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSPF 88
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 2-27 1.68e-06

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 46.83  E-value: 1.68e-06
                           10        20
                   ....*....|....*....|....*.
gi 29179426      2 PGDYSILVKYNDKHIPGSPFTAKITD 27
Cdd:smart00557  67 PGDYTVTVKFGGEHIPGSPFTVKVGP 92
Filamin pfam00630
Filamin/ABP280 repeat;
33-106 1.96e-06

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 46.51  E-value: 1.96e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 29179426    33 SQVKLGSAADFLLDISETDlSTLTASIKAPSGRDEPCLLKRLPNNHIGISFIPREVGEHLVSIKKNGNHVANSP 106
Cdd:pfam00630  15 EPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSP 87
Filamin pfam00630
Filamin/ABP280 repeat;
2-22 3.58e-04

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 39.96  E-value: 3.58e-04
                          10        20
                  ....*....|....*....|.
gi 29179426     2 PGDYSILVKYNDKHIPGSPFT 22
Cdd:pfam00630  69 PGDYTVSVKFNGQHIPGSPFK 89
 
Name Accession Description Interval E-value
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 310-400 7.29e-31

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 116.16  E-value: 7.29e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29179426    310 AHKVRAGGPGLERGEAGIPAEFSIWTREAGAGGLSIAVEGPS--KAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEH 387
Cdd:smart00557   1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80

                           90
                   ....*....|...
gi 29179426    388 IPDSPYLVPVIAP 400
Cdd:smart00557  81 IPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 119-208 7.35e-28

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 107.69  E-value: 7.35e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29179426    119 ARRAKVYGQGLSEGRTFEMSDFIVDTRDAGYGGISLAVEGPS--KVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADEH 196
Cdd:smart00557   1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80

                           90
                   ....*....|..
gi 29179426    197 VPGSPFTVKISG 208
Cdd:smart00557  81 IPGSPFTVKVGP 92
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 629-718 3.23e-26

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 102.68  E-value: 3.23e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29179426    629 ASKVTSKGAGLSKAFVGQKSSFLVDCSKAGSNMLLIGVHGPTTPCEEVSMKHVGKQQYNVTYVVKERGDYVLAVKWGEEH 708
Cdd:smart00557   1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80

                           90
                   ....*....|
gi 29179426    709 IPGSPFHVTV 718
Cdd:smart00557  81 IPGSPFTVKV 90
Filamin pfam00630
Filamin/ABP280 repeat;
308-393 9.29e-24

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 95.82  E-value: 9.29e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29179426   308 GGAHKVRAGGPGLERGEAGIPAEFSIWTREAGaGGLSIAVEGPS--KAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFND 385
Cdd:pfam00630   2 ADASKVKASGPGLEPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDgsPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNG 80


                  ....*...
gi 29179426   386 EHIPDSPY 393
Cdd:pfam00630  81 QHIPGSPF 88
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 501-590 4.28e-22

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 91.13  E-value: 4.28e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29179426    501 PALVSAYGAGLETGTTGIQSEFFINTTQAGPGTLSVTIEGPS--KVKMDCQEIPEG-YKVMYTPMAPGNYLIGVKYGGpN 577
Cdd:smart00557   1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkKVPVEVKDNGDGtYTVSYTPTEPGDYTVTVKFGG-E 79

                           90
                   ....*....|...
gi 29179426    578 HISRSPFKAKVTG 590
Cdd:smart00557  80 HIPGSPFTVKVGP 92
Filamin pfam00630
Filamin/ABP280 repeat;
117-203 4.55e-22

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 90.81  E-value: 4.55e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29179426   117 GDARRAKVYGQGLSEGRTFEMSDFIVDTRDAGyGGISLAVEGPS--KVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFAD 194
Cdd:pfam00630   2 ADASKVKASGPGLEPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDgsPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNG 80


                  ....*....
gi 29179426   195 EHVPGSPFT 203
Cdd:pfam00630  81 QHIPGSPFK 89
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 418-495 5.86e-21

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 87.66  E-value: 5.86e-21
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 29179426    418 KVNQPASFAIRLNGA-KGKIDAKVHSPSGAVEECHVSELEPDKYAVRFIPHENGIHTIDVKFNGSHVVGSPFKVRVGEP 495
Cdd:smart00557  15 VVGEPAEFTVDTRDAgGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKVGPA 93
Filamin pfam00630
Filamin/ABP280 repeat;
418-489 7.23e-20

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 84.65  E-value: 7.23e-20
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 29179426   418 KVNQPASFAIRLNGAKGKIDAKVHSPSGAVEECHVSELEPDKYAVRFIPHENGIHTIDVKFNGSHVVGSPFK 489
Cdd:pfam00630  18 VVGKPAEFTVDTRDAGGEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSPFK 89
Filamin pfam00630
Filamin/ABP280 repeat;
626-715 9.57e-18

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 78.48  E-value: 9.57e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29179426   626 SSDASKVTSKGAGLSKAFVGQKSSFLVDCSKAGSNmLLIGVHGPTTPCEEVSMKHVGKQQYNVTYVVKERGDYVLAVKWG 705
Cdd:pfam00630   1 AADASKVKASGPGLEPGVVGKPAEFTVDTRDAGGE-GEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFN 79

                          90
                  ....*....|
gi 29179426   706 EEHIPGSPFH 715
Cdd:pfam00630  80 GQHIPGSPFK 89
Filamin pfam00630
Filamin/ABP280 repeat;
498-585 2.67e-16

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 74.25  E-value: 2.67e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29179426   498 AGNPALVSAYGAGLETGTTGIQSEFFINTTQAGpGTLSVTIEGPSKVKMDCQEIPEG---YKVMYTPMAPGNYLIGVKYG 574
Cdd:pfam00630   1 AADASKVKASGPGLEPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDGSPVPVEVTDNGdgtYTVSYTPTEPGDYTVSVKFN 79

                          90
                  ....*....|.
gi 29179426   575 GpNHISRSPFK 585
Cdd:pfam00630  80 G-QHIPGSPFK 89
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 243-304 1.26e-13

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 66.86  E-value: 1.26e-13
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 29179426    243 SSDMSAHVTSPSGHVTEAEIVPMGKNSHCVRFVPQEMGVHTVSVKYRGQHVTGSPFQFTVGP 304
Cdd:smart00557  31 GGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKVGP 92
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 33-114 6.96e-13

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 64.93  E-value: 6.96e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29179426     33 SQVKLGSAADFLLDISETDLSTLTASIKAPSGRDEPCLLKRLPNNHIGISFIPREVGEHLVSIKKNGNHVANSPVSIMVV 112
Cdd:smart00557  12 EKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKVG 91


                   ..
gi 29179426    113 QS 114
Cdd:smart00557  92 PA 93
Filamin pfam00630
Filamin/ABP280 repeat;
249-298 9.10e-11

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 58.84  E-value: 9.10e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 29179426   249 HVTSPSGHVTEAEIVPMGKNSHCVRFVPQEMGVHTVSVKYRGQHVTGSPF 298
Cdd:pfam00630  39 EVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSPF 88
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 2-27 1.68e-06

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 46.83  E-value: 1.68e-06
                           10        20
                   ....*....|....*....|....*.
gi 29179426      2 PGDYSILVKYNDKHIPGSPFTAKITD 27
Cdd:smart00557  67 PGDYTVTVKFGGEHIPGSPFTVKVGP 92
Filamin pfam00630
Filamin/ABP280 repeat;
33-106 1.96e-06

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 46.51  E-value: 1.96e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 29179426    33 SQVKLGSAADFLLDISETDlSTLTASIKAPSGRDEPCLLKRLPNNHIGISFIPREVGEHLVSIKKNGNHVANSP 106
Cdd:pfam00630  15 EPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSP 87
Filamin pfam00630
Filamin/ABP280 repeat;
2-22 3.58e-04

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 39.96  E-value: 3.58e-04
                          10        20
                  ....*....|....*....|.
gi 29179426     2 PGDYSILVKYNDKHIPGSPFT 22
Cdd:pfam00630  69 PGDYTVSVKFNGQHIPGSPFK 89
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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