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Conserved domains on  [gi|109732738|gb|AAI16367|]
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Ly6g6c protein [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TFP_LU_ECD_Ly6G6c cd23546
extracellular domain (ECD) found in lymphocyte antigen 6 complex locus protein G6c (Ly6G6c) ...
 18-99 6.66e-56

extracellular domain (ECD) found in lymphocyte antigen 6 complex locus protein G6c (Ly6G6c) and similar proteins; Ly6G6c is a glycosylated, GPI-anchored, cell surface molecule, located on filopodia, which could act as cell receptor with potential roles in signaling or cell-cell interactions. Ly6G6c contains an extracellular domain (ECD) which belongs to Ly-6 antigen/uPA receptor-like (LU) superfamily and exhibits a snake toxin-like fold (also known as three-finger toxin/3FTx fold or three-fingered protein/TFP domain fold).


:

Pssm-ID: 467076  Cd Length: 82  Bit Score: 168.70  E-value: 6.66e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109732738  18 SADTRCHSCYKVPVLGCVDRQSCRLEPGHKCLTTNVYLGKMWVFSNLRCGTPEEPCREVFNETNHKLGLNYNTTCCDKDN 97
Cdd:cd23546    1 SADIRCHSCYKVPVLGCVDRQSCRLEPGQQCLTTHAYLGKMWVFSNLRCGTPEEPCQEAFNQTNRKLGLTYNTTCCNKDN 80


                 ..
gi 109732738  98 CN 99
Cdd:cd23546   81 CN 82
 
Name Accession Description Interval E-value
TFP_LU_ECD_Ly6G6c cd23546
extracellular domain (ECD) found in lymphocyte antigen 6 complex locus protein G6c (Ly6G6c) ...
 18-99 6.66e-56

extracellular domain (ECD) found in lymphocyte antigen 6 complex locus protein G6c (Ly6G6c) and similar proteins; Ly6G6c is a glycosylated, GPI-anchored, cell surface molecule, located on filopodia, which could act as cell receptor with potential roles in signaling or cell-cell interactions. Ly6G6c contains an extracellular domain (ECD) which belongs to Ly-6 antigen/uPA receptor-like (LU) superfamily and exhibits a snake toxin-like fold (also known as three-finger toxin/3FTx fold or three-fingered protein/TFP domain fold).


Pssm-ID: 467076  Cd Length: 82  Bit Score: 168.70  E-value: 6.66e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109732738  18 SADTRCHSCYKVPVLGCVDRQSCRLEPGHKCLTTNVYLGKMWVFSNLRCGTPEEPCREVFNETNHKLGLNYNTTCCDKDN 97
Cdd:cd23546    1 SADIRCHSCYKVPVLGCVDRQSCRLEPGQQCLTTHAYLGKMWVFSNLRCGTPEEPCQEAFNQTNRKLGLTYNTTCCNKDN 80


                 ..
gi 109732738  98 CN 99
Cdd:cd23546   81 CN 82
LU smart00134
Ly-6 antigen / uPA receptor -like domain; Three-fold repeated domain in urokinase-type ...
 22-103 3.18e-03

Ly-6 antigen / uPA receptor -like domain; Three-fold repeated domain in urokinase-type plasminogen activator receptor; occurs singly in other GPI-linked cell-surface glycoproteins (Ly-6 family, CD59, thymocyte B cell antigen, Sgp-2). Topology of these domains is similar to that of snake venom neurotoxins.


Pssm-ID: 214530  Cd Length: 85  Bit Score: 34.43  E-value: 3.18e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109732738    22 RCHSCYKVPVLGCVDRQSCRlEPGHKCLTTNVYLGKMWVFS--NLRCGTPEEPCREVFNETNHKLGlNYNTTCCDKDNCN 99
Cdd:smart00134   2 QCYSCTGNPDSSCSSEEECR-SPDDVCLTVVAEVISDSRGSvvYKGCATSPICPGSHGYEINLTIA-FLKVSCCQTDLCN 79


                   ....
gi 109732738   100 SPAP 103
Cdd:smart00134  80 AAGP 83
 
Name Accession Description Interval E-value
TFP_LU_ECD_Ly6G6c cd23546
extracellular domain (ECD) found in lymphocyte antigen 6 complex locus protein G6c (Ly6G6c) ...
 18-99 6.66e-56

extracellular domain (ECD) found in lymphocyte antigen 6 complex locus protein G6c (Ly6G6c) and similar proteins; Ly6G6c is a glycosylated, GPI-anchored, cell surface molecule, located on filopodia, which could act as cell receptor with potential roles in signaling or cell-cell interactions. Ly6G6c contains an extracellular domain (ECD) which belongs to Ly-6 antigen/uPA receptor-like (LU) superfamily and exhibits a snake toxin-like fold (also known as three-finger toxin/3FTx fold or three-fingered protein/TFP domain fold).


Pssm-ID: 467076  Cd Length: 82  Bit Score: 168.70  E-value: 6.66e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109732738  18 SADTRCHSCYKVPVLGCVDRQSCRLEPGHKCLTTNVYLGKMWVFSNLRCGTPEEPCREVFNETNHKLGLNYNTTCCDKDN 97
Cdd:cd23546    1 SADIRCHSCYKVPVLGCVDRQSCRLEPGQQCLTTHAYLGKMWVFSNLRCGTPEEPCQEAFNQTNRKLGLTYNTTCCNKDN 80


                 ..
gi 109732738  98 CN 99
Cdd:cd23546   81 CN 82
TFP_LU_ECD_C9orf57 cd23610
extracellular domain (ECD) found in Homo sapiens uncharacterized protein C9orf57 and similar ...
 23-99 5.32e-05

extracellular domain (ECD) found in Homo sapiens uncharacterized protein C9orf57 and similar proteins; C9orf57 contains an extracellular domain (ECD) that belongs to Ly-6 antigen/uPA receptor-like (LU) superfamily and exhibits a snake toxin-like fold (also known as three-finger toxin/3FTx fold or three-fingered protein/TFP domain fold).


Pssm-ID: 467130  Cd Length: 83  Bit Score: 39.03  E-value: 5.32e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 109732738  23 CHSCYK-VPVLGC-VDRQSCRLEPGHKCLTTNVYLGKMWVFSNLRCGTPEEPCrevFNETNHKLGLNYNTTCCDKDNCN 99
Cdd:cd23610    7 CRMCNLsKPFHGCtLGGGTCLAKPGQYCKTERHIKGGIEWFSIKGCTKNSEEC---GSTKEVGYSGRVTTTCCNSHMCN 82
TFP_LU_ECD_PATE3 cd23579
extracellular domain (ECD) found in prostate and testis expressed protein 3 (PATE3) and ...
 40-99 2.96e-03

extracellular domain (ECD) found in prostate and testis expressed protein 3 (PATE3) and similar proteins; PATE3 (also called acrosomal vesicle protein HEL-127, or PATE-like protein DJ (PATE-DJ)) is a member of the prostate and testis expression (PATE)-like family of proteins that likely play important roles in reproductive and neuronal physiology. They are expressed mainly in the male genital tract and involved in sperm-oolemma fusion and penetration, but not sperm-zona binding. PATE3 contains an extracellular domain (ECD), which belongs to Ly-6 antigen/uPA receptor-like (LU) superfamily and exhibits a snake toxin-like fold (also known as three-finger toxin/3FTx fold or three-fingered protein/TFP domain fold).


Pssm-ID: 467109  Cd Length: 80  Bit Score: 34.33  E-value: 2.96e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 109732738  40 CRLEPGHKCLTTNVYLGKMWVFSNLRCgtpEEPCRevfNETNHKLGLNYNTTCCDKDNCN 99
Cdd:cd23579   26 CTAQKDESCMRLRIYQGDTLQLSYMVC---QKFCR---DLTYHFNNRTYVHTCCNKDYCN 79
LU smart00134
Ly-6 antigen / uPA receptor -like domain; Three-fold repeated domain in urokinase-type ...
 22-103 3.18e-03

Ly-6 antigen / uPA receptor -like domain; Three-fold repeated domain in urokinase-type plasminogen activator receptor; occurs singly in other GPI-linked cell-surface glycoproteins (Ly-6 family, CD59, thymocyte B cell antigen, Sgp-2). Topology of these domains is similar to that of snake venom neurotoxins.


Pssm-ID: 214530  Cd Length: 85  Bit Score: 34.43  E-value: 3.18e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109732738    22 RCHSCYKVPVLGCVDRQSCRlEPGHKCLTTNVYLGKMWVFS--NLRCGTPEEPCREVFNETNHKLGlNYNTTCCDKDNCN 99
Cdd:smart00134   2 QCYSCTGNPDSSCSSEEECR-SPDDVCLTVVAEVISDSRGSvvYKGCATSPICPGSHGYEINLTIA-FLKVSCCQTDLCN 79


                   ....
gi 109732738   100 SPAP 103
Cdd:smart00134  80 AAGP 83
TFP_LU_ECD_Ly6G5b cd23544
extracellular domain (ECD) found in lymphocyte antigen 6 complex locus protein G5b (Ly6G5b) ...
 22-100 4.60e-03

extracellular domain (ECD) found in lymphocyte antigen 6 complex locus protein G5b (Ly6G5b) and similar proteins; Ly6G5b is a glycosylated, potentially secreted protein which could act as ligand for other cell-surface receptors and could thus potentially have a role in cell signaling. It contains an extracellular domain (ECD) which belongs to Ly-6 antigen/uPA receptor-like (LU) superfamily and exhibits a snake toxin-like fold (also known as three-finger toxin/3FTx fold or three-fingered protein/TFP domain fold).


Pssm-ID: 467074  Cd Length: 82  Bit Score: 33.92  E-value: 4.60e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109732738  22 RCHSCY-KVPVLGCVDRQS-CRLEPGHKCLTTNVYLGKMWVFSNLRCG-TPEEPCREVFNETNHklGLNYNTTCCDKDNC 98
Cdd:cd23544    3 RCHLCLlEDPSIGCISGSEkCTPSSGEPCMTITIYYEGKVRFLVRGCGqHSSYRCGERKKTYVS--GYWYNARCCQYDYC 80


                 ..
gi 109732738  99 NS 100
Cdd:cd23544   81 NS 82
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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