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Conserved domains on  [gi|111599987|gb|AAI19122|]
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Zona pellucida 3 receptor [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PHA02927 super family cl33700
secreted complement-binding protein; Provisional
 50-278 2.02e-46

secreted complement-binding protein; Provisional


The actual alignment was detected with superfamily member PHA02927:

Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 164.06  E-value: 2.02e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 111599987  50 YESTTFPSGTVLKYTCHHGFKR--VNSSHLSCDENGsWVYSTFCARKRCKNPGELVNGKVEIpSDLLVGSIIEFSCSKGY 127
Cdd:PHA02927  39 DANANYNIGDTIEYLCLPGYRKqkMGPIYAKCTGTG-WTLFNQCIKRRCPSPRDIDNGQLDI-GGVDFGSSITYSCNSGY 116

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 111599987 128 LLIGSATSRCEVQGKG-VDWSDSLPECVIATCEPPPPISNGKHSGRDDdLYTFGSVVIYNCDPTFTLLGNASIVCTVvnr 206
Cdd:PHA02927 117 QLIGESKSYCELGSTGsMVWNPEAPICESVKCQSPPSISNGRHNGYED-FYTDGSVVTYSCNSGYSLIGNSGVLCSG--- 192

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 111599987 207 tvGVWRpHPPACQKIVCHRPQIPKGYLAPGFRQFYAYRDALEIRCKKGFILRGSSVIHCEANGEWFPSIPTC 278
Cdd:PHA02927 193 --GEWS-DPPTCQIVKCPHPTISNGYLSSGFKRSYSYNDNVDFKCKYGYKLSGSSSSTCSPGNTWQPELPKC 261
C4bp_oligo super family cl39787
Oligomerization domain of C4b-binding protein alpha; This is the C-terminal oligomerization ...
 512-558 2.50e-15

Oligomerization domain of C4b-binding protein alpha; This is the C-terminal oligomerization domain found in C4b-binding protein (C4BP), which contains 14 cysteines that form 7 intermolecular disulfide bridges. C4BP is a plasma glycoprotein complex of 570 kDa, which is mainly produced in the liver. C4BP is the major inhibitor of complement activation, the major isoform consists of 7alpha and one beta-chain where each alpha-chain comprises eight complement control domain proteins (CCPs) and a C-terminal oligomerization domain. This domain carries a stretch of 42-45 amino acids that has been shown to be required for ring formation.


The actual alignment was detected with superfamily member pfam18453:

Pssm-ID: 436513  Cd Length: 49  Bit Score: 70.17  E-value: 2.50e-15
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 111599987  512 EVLEDCRIVSRGAQLLHCLSSPEDVHRALKVYKLFLEIERLEHQKEK 558
Cdd:pfam18453   1 EFPEGCEQVLTGKKLMQCLPNPEDVKMALEVYKLSLEIELLELQIDK 47
PHA02927 super family cl33700
secreted complement-binding protein; Provisional
 307-509 1.25e-11

secreted complement-binding protein; Provisional


The actual alignment was detected with superfamily member PHA02927:

Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 65.44  E-value: 1.25e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 111599987 307 FEIGAKLKYQCKPGYRASLNDPQTVTCQENlTWSSTNGCERICCPTP-DMEKIKIvserrDFTGTciyAYGDYVFYICNE 385
Cdd:PHA02927  44 YNIGDTIEYLCLPGYRKQKMGPIYAKCTGT-GWTLFNQCIKRRCPSPrDIDNGQL-----DIGGV---DFGSSITYSCNS 114

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 111599987 386 GsYPMSTDGRSSCQADGK----WDPAIPSCQA---------DSGLQNRLALFTFPNISETNVTNKTYLF---------GH 443
Cdd:PHA02927 115 G-YQLIGESKSYCELGSTgsmvWNPEAPICESvkcqsppsiSNGRHNGYEDFYTDGSVVTYSCNSGYSLignsgvlcsGG 193

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 111599987 444 EENSTEHAMKGVCLKPMVINGNLSVE-RVIYAELENITIQCDPGYTIVGSPNIICS-NRTWYPEVPSC 509
Cdd:PHA02927 194 EWSDPPTCQIVKCPHPTISNGYLSSGfKRSYSYNDNVDFKCKYGYKLSGSSSSTCSpGNTWQPELPKC 261
 
Name Accession Description Interval E-value
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 50-278 2.02e-46

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 164.06  E-value: 2.02e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 111599987  50 YESTTFPSGTVLKYTCHHGFKR--VNSSHLSCDENGsWVYSTFCARKRCKNPGELVNGKVEIpSDLLVGSIIEFSCSKGY 127
Cdd:PHA02927  39 DANANYNIGDTIEYLCLPGYRKqkMGPIYAKCTGTG-WTLFNQCIKRRCPSPRDIDNGQLDI-GGVDFGSSITYSCNSGY 116

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 111599987 128 LLIGSATSRCEVQGKG-VDWSDSLPECVIATCEPPPPISNGKHSGRDDdLYTFGSVVIYNCDPTFTLLGNASIVCTVvnr 206
Cdd:PHA02927 117 QLIGESKSYCELGSTGsMVWNPEAPICESVKCQSPPSISNGRHNGYED-FYTDGSVVTYSCNSGYSLIGNSGVLCSG--- 192

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 111599987 207 tvGVWRpHPPACQKIVCHRPQIPKGYLAPGFRQFYAYRDALEIRCKKGFILRGSSVIHCEANGEWFPSIPTC 278
Cdd:PHA02927 193 --GEWS-DPPTCQIVKCPHPTISNGYLSSGFKRSYSYNDNVDFKCKYGYKLSGSSSSTCSPGNTWQPELPKC 261
C4bp_oligo pfam18453
Oligomerization domain of C4b-binding protein alpha; This is the C-terminal oligomerization ...
 512-558 2.50e-15

Oligomerization domain of C4b-binding protein alpha; This is the C-terminal oligomerization domain found in C4b-binding protein (C4BP), which contains 14 cysteines that form 7 intermolecular disulfide bridges. C4BP is a plasma glycoprotein complex of 570 kDa, which is mainly produced in the liver. C4BP is the major inhibitor of complement activation, the major isoform consists of 7alpha and one beta-chain where each alpha-chain comprises eight complement control domain proteins (CCPs) and a C-terminal oligomerization domain. This domain carries a stretch of 42-45 amino acids that has been shown to be required for ring formation.


Pssm-ID: 436513  Cd Length: 49  Bit Score: 70.17  E-value: 2.50e-15
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 111599987  512 EVLEDCRIVSRGAQLLHCLSSPEDVHRALKVYKLFLEIERLEHQKEK 558
Cdd:pfam18453   1 EFPEGCEQVLTGKKLMQCLPNPEDVKMALEVYKLSLEIELLELQIDK 47
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 307-509 1.25e-11

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 65.44  E-value: 1.25e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 111599987 307 FEIGAKLKYQCKPGYRASLNDPQTVTCQENlTWSSTNGCERICCPTP-DMEKIKIvserrDFTGTciyAYGDYVFYICNE 385
Cdd:PHA02927  44 YNIGDTIEYLCLPGYRKQKMGPIYAKCTGT-GWTLFNQCIKRRCPSPrDIDNGQL-----DIGGV---DFGSSITYSCNS 114

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 111599987 386 GsYPMSTDGRSSCQADGK----WDPAIPSCQA---------DSGLQNRLALFTFPNISETNVTNKTYLF---------GH 443
Cdd:PHA02927 115 G-YQLIGESKSYCELGSTgsmvWNPEAPICESvkcqsppsiSNGRHNGYEDFYTDGSVVTYSCNSGYSLignsgvlcsGG 193

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 111599987 444 EENSTEHAMKGVCLKPMVINGNLSVE-RVIYAELENITIQCDPGYTIVGSPNIICS-NRTWYPEVPSC 509
Cdd:PHA02927 194 EWSDPPTCQIVKCPHPTISNGYLSSGfKRSYSYNDNVDFKCKYGYKLSGSSSSTCSpGNTWQPELPKC 261
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 158-219 2.11e-11

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 59.40  E-value: 2.11e-11
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 111599987 158 CEPPPPISNGKHSGRDDDlYTFGSVVIYNCDPTFTLLGNASIVCTVvnrtVGVWRPHPPACQ 219
Cdd:cd00033    1 CPPPPVPENGTVTGSKGS-YSYGSTVTYSCNEGYTLVGSSTITCTE----NGGWSPPPPTCE 57
Sushi pfam00084
Sushi repeat (SCR repeat);
283-343 8.99e-10

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 54.43  E-value: 8.99e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 111599987  283 CTNIPDISYASWEGYKfplrnfEVFEIGAKLKYQCKPGYRasLNDPQTVTCQENLTWSSTN 343
Cdd:pfam00084   1 CPPPPDIPNGKVSATK------NEYNYGASVSYECDPGYR--LVGSPTITCQEDGTWSPPF 53
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 158-218 8.22e-09

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 51.76  E-value: 8.22e-09
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 111599987   158 CEPPPPISNGKHSGRDDDlYTFGSVVIYNCDPTFTLLGNASIVCTvvnrTVGVWRPHPPAC 218
Cdd:smart00032   1 CPPPPDIENGTVTSSSGT-YSYGDTVTYSCDPGYTLIGSSTITCL----ENGTWSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
158-218 4.65e-08

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 49.81  E-value: 4.65e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 111599987  158 CEPPPPISNGKHSGRDDDlYTFGSVVIYNCDPTFTLLGNASIVCTvvnrTVGVWRPHPPAC 218
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNE-YNYGASVSYECDPGYRLVGSPTITCQ----EDGTWSPPFPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 456-510 4.99e-07

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 46.69  E-value: 4.99e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 111599987 456 CLKPMVI-NGNLSVERVIYAELENITIQCDPGYTIVGSPNIIC-SNRTWYPEVPSCQ 510
Cdd:cd00033    1 CPPPPVPeNGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCtENGGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 350-411 1.97e-06

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 45.21  E-value: 1.97e-06
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 111599987   350 CPTPDMEKIKIVSerrdfTGTCIYAYGDYVFYICNEGsYPMSTDGRSSCQADGKWDPAIPSC 411
Cdd:smart00032   1 CPPPPDIENGTVT-----SSSGTYSYGDTVTYSCDPG-YTLIGSSTITCLENGTWSPPPPTC 56
 
Name Accession Description Interval E-value
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 50-278 2.02e-46

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 164.06  E-value: 2.02e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 111599987  50 YESTTFPSGTVLKYTCHHGFKR--VNSSHLSCDENGsWVYSTFCARKRCKNPGELVNGKVEIpSDLLVGSIIEFSCSKGY 127
Cdd:PHA02927  39 DANANYNIGDTIEYLCLPGYRKqkMGPIYAKCTGTG-WTLFNQCIKRRCPSPRDIDNGQLDI-GGVDFGSSITYSCNSGY 116

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 111599987 128 LLIGSATSRCEVQGKG-VDWSDSLPECVIATCEPPPPISNGKHSGRDDdLYTFGSVVIYNCDPTFTLLGNASIVCTVvnr 206
Cdd:PHA02927 117 QLIGESKSYCELGSTGsMVWNPEAPICESVKCQSPPSISNGRHNGYED-FYTDGSVVTYSCNSGYSLIGNSGVLCSG--- 192

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 111599987 207 tvGVWRpHPPACQKIVCHRPQIPKGYLAPGFRQFYAYRDALEIRCKKGFILRGSSVIHCEANGEWFPSIPTC 278
Cdd:PHA02927 193 --GEWS-DPPTCQIVKCPHPTISNGYLSSGFKRSYSYNDNVDFKCKYGYKLSGSSSSTCSPGNTWQPELPKC 261
PHA02639 PHA02639
EEV host range protein; Provisional
 96-291 8.63e-29

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 116.30  E-value: 8.63e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 111599987  96 CKNPGELVNGKV-EIPSDLLVGSIIEFSCSKGYLLIGSATSRCEVQGKGVDWSDSLPECVIATCEPPPPISNGKHSGRdD 174
Cdd:PHA02639  22 CDKPDDISNGFItELMEKYEIGKLIEYTCNTDYALIGDRFRTCIKDKNNAIWSNKAPFCMLKECNDPPSIINGKIYNK-R 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 111599987 175 DLYTFGSVVIYNCDP----TFTLLGNASIVCTVVNRtvgvWRPHPPACQKIVCHRPQIPKGYL--APGFRQFYaYRDALE 248
Cdd:PHA02639 101 EMYKVGDEIYYVCNEhkgvQYSLVGNEKITCIQDKS----WKPDPPICKMINCRFPALQNGYIngIPSNKKFY-YKTRVG 175

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 111599987 249 IRCKKGFILRGSSVIHCEANGEWFPSIPTCEPNgcTNIPDISY 291
Cdd:PHA02639 176 FSCKSGFDLVGEKYSTCNINATWFPSIPTCVRN--KPIDDIIY 216
PHA02831 PHA02831
EEV host range protein; Provisional
 50-278 3.10e-18

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 85.04  E-value: 3.10e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 111599987  50 YESTTFPSGTVLKYTCHHGFkrvNSSHLSCDeNGSWVYSTFCARKR-CKNPGELVNGKveipsdllvgsiiefscskgyl 128
Cdd:PHA02831  35 YENKVYEENENLEYKCNNNF---DKVFVTCN-NGSWSTKNMCIGKRnCKDPVTILNGY---------------------- 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 111599987 129 ligsatsrcevqgkgvdwsdslpecviatceppppISNGKhsgrddDLYTFGSVVIYNCD----PTFTLLGNASIVCtvV 204
Cdd:PHA02831  89 -----------------------------------IKNKK------DQYSFGDSVTYACKvnklEKYSIVGNETVKC--I 125

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 111599987 205 NrtvGVWRPHPPACQKIVCHRPQIPKGYLAPGFRQFYaYRDALEIRCKKGFILRGSSVIHCEANGEWFPSIPTC 278
Cdd:PHA02831 126 N---KQWVPKYPVCKLIRCKYPALQNGFLNVFEKKFY-YGDIVNFKCKKGFILLGSSVSTCDINSIWYPGIPKC 195
PHA02817 PHA02817
EEV Host range protein; Provisional
 153-284 5.63e-16

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 77.29  E-value: 5.63e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 111599987 153 CVIATCEPPPPISNGKHSGRDDDlYTFGSVVIYNCDPT-----FTLLGNASIVCtvvnRTVGVWRPHPPACQKIVCHRPQ 227
Cdd:PHA02817  19 CDLNKCCYPPSIKNGYIYNKKTE-YNIGSNVTFFCGNNtrgvrYTLVGEKNIIC----EKDGKWNKEFPVCKIIRCRFPA 93

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 111599987 228 IPKGYL--APGFRQFYaYRDALEIRCKKGFILRGSSVIHCEANGEWFPSIPTCEPNGCT 284
Cdd:PHA02817  94 LQNGFVngIPDSKKFY-YESEVSFSCKPGFVLIGTKYSVCGINSSWIPKVPICSRDNIT 151
C4bp_oligo pfam18453
Oligomerization domain of C4b-binding protein alpha; This is the C-terminal oligomerization ...
 512-558 2.50e-15

Oligomerization domain of C4b-binding protein alpha; This is the C-terminal oligomerization domain found in C4b-binding protein (C4BP), which contains 14 cysteines that form 7 intermolecular disulfide bridges. C4BP is a plasma glycoprotein complex of 570 kDa, which is mainly produced in the liver. C4BP is the major inhibitor of complement activation, the major isoform consists of 7alpha and one beta-chain where each alpha-chain comprises eight complement control domain proteins (CCPs) and a C-terminal oligomerization domain. This domain carries a stretch of 42-45 amino acids that has been shown to be required for ring formation.


Pssm-ID: 436513  Cd Length: 49  Bit Score: 70.17  E-value: 2.50e-15
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 111599987  512 EVLEDCRIVSRGAQLLHCLSSPEDVHRALKVYKLFLEIERLEHQKEK 558
Cdd:pfam18453   1 EFPEGCEQVLTGKKLMQCLPNPEDVKMALEVYKLSLEIELLELQIDK 47
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 153-411 4.27e-14

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 72.76  E-value: 4.27e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 111599987 153 CVIATCEPPPPISNGKHSGR----DDDLYTFGSVVIYNCDPTF--TLLGNASIVCTVVNRTVGvwrphpPACQKIVCHRP 226
Cdd:PHA02927  16 CVLSCCTIPSRPINMKFKNSvetdANANYNIGDTIEYLCLPGYrkQKMGPIYAKCTGTGWTLF------NQCIKRRCPSP 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 111599987 227 Q-IPKGYLAPGFRQFYAyrdALEIRCKKGFILRGSSVIHCEANGE----WFPSIPTCEPNGCTNIPDISYASWEGYKfpl 301
Cdd:PHA02927  90 RdIDNGQLDIGGVDFGS---SITYSCNSGYQLIGESKSYCELGSTgsmvWNPEAPICESVKCQSPPSISNGRHNGYE--- 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 111599987 302 rnfEVFEIGAKLKYQCKPGYraSLNDPQTVTCQENlTWSSTNGCERICCPTPDMEKIKIVSERRDftgtcIYAYGDYVFY 381
Cdd:PHA02927 164 ---DFYTDGSVVTYSCNSGY--SLIGNSGVLCSGG-EWSDPPTCQIVKCPHPTISNGYLSSGFKR-----SYSYNDNVDF 232

                        250       260       270
                 ....*....|....*....|....*....|
gi 111599987 382 ICNEGsYPMSTDGRSSCQADGKWDPAIPSC 411
Cdd:PHA02927 233 KCKYG-YKLSGSSSSTCSPGNTWQPELPKC 261
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 307-509 1.25e-11

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 65.44  E-value: 1.25e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 111599987 307 FEIGAKLKYQCKPGYRASLNDPQTVTCQENlTWSSTNGCERICCPTP-DMEKIKIvserrDFTGTciyAYGDYVFYICNE 385
Cdd:PHA02927  44 YNIGDTIEYLCLPGYRKQKMGPIYAKCTGT-GWTLFNQCIKRRCPSPrDIDNGQL-----DIGGV---DFGSSITYSCNS 114

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 111599987 386 GsYPMSTDGRSSCQADGK----WDPAIPSCQA---------DSGLQNRLALFTFPNISETNVTNKTYLF---------GH 443
Cdd:PHA02927 115 G-YQLIGESKSYCELGSTgsmvWNPEAPICESvkcqsppsiSNGRHNGYEDFYTDGSVVTYSCNSGYSLignsgvlcsGG 193

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 111599987 444 EENSTEHAMKGVCLKPMVINGNLSVE-RVIYAELENITIQCDPGYTIVGSPNIICS-NRTWYPEVPSC 509
Cdd:PHA02927 194 EWSDPPTCQIVKCPHPTISNGYLSSGfKRSYSYNDNVDFKCKYGYKLSGSSSSTCSpGNTWQPELPKC 261
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 158-219 2.11e-11

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 59.40  E-value: 2.11e-11
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 111599987 158 CEPPPPISNGKHSGRDDDlYTFGSVVIYNCDPTFTLLGNASIVCTVvnrtVGVWRPHPPACQ 219
Cdd:cd00033    1 CPPPPVPENGTVTGSKGS-YSYGSTVTYSCNEGYTLVGSSTITCTE----NGGWSPPPPTCE 57
Sushi pfam00084
Sushi repeat (SCR repeat);
283-343 8.99e-10

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 54.43  E-value: 8.99e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 111599987  283 CTNIPDISYASWEGYKfplrnfEVFEIGAKLKYQCKPGYRasLNDPQTVTCQENLTWSSTN 343
Cdd:pfam00084   1 CPPPPDIPNGKVSATK------NEYNYGASVSYECDPGYR--LVGSPTITCQEDGTWSPPF 53
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 96-154 9.36e-10

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 54.39  E-value: 9.36e-10
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 111599987  96 CKNPGELVNGKVEIPSD-LLVGSIIEFSCSKGYLLIGSATSRCEVQGKgvdWSDSLPECV 154
Cdd:cd00033    1 CPPPPVPENGTVTGSKGsYSYGSTVTYSCNEGYTLVGSSTITCTENGG---WSPPPPTCE 57
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 16-278 1.79e-09

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 59.33  E-value: 1.79e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 111599987  16 TLFQMTLATVLMAPVLGDCGPPPLlpfaSPTNQLYESTTFPSGTVLKYTCHHGFKRVNSSHLScdENGSWVYSTFCaRKR 95
Cdd:PHA02954   3 TISVVTLLCVLPAVVYSTCTVPTM----NNAKLTSTETSFNDKQKVTFTCDSGYYSLDPNAVC--ETDKWKYENPC-KKM 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 111599987  96 CKNP---GELVNGKVeipsdLLVGSIIEFSCSKGylligSATSRCEVQGKGVDWSDSLpECVIATCEPPPPISNGKHSGR 172
Cdd:PHA02954  76 CTVSdyvSELYDKPL-----YEVNSTITLICKDE-----TKYFRCEEKNGNTSWNDTV-TCPNAECQPLQLEHGSCQPVK 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 111599987 173 DDdlYTFGSVVIYNCDPTFTLLGNASIVCTVVNRTVgvwrphPPACQKiVCHRPQIPKGYLAPgfrQFYAYRDALEIRCK 252
Cdd:PHA02954 145 EK--YSFGEHITINCDVGYEVIGASYISCTANSWNV------IPSCQQ-KCDIPSLSNGLISG---STFSIGGVIHLSCK 212

                        250       260
                 ....*....|....*....|....*.
gi 111599987 253 KGFILRGSSVIHCeANGEWFPSIPTC 278
Cdd:PHA02954 213 SGFTLTGSPSSTC-IDGKWNPVLPIC 237
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 223-279 4.62e-09

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 52.47  E-value: 4.62e-09
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 111599987 223 CHRPQIPKGYLAPGFRQFYAYRDALEIRCKKGFILRGSSVIHCEANGEWFPSIPTCE 279
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 158-218 8.22e-09

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 51.76  E-value: 8.22e-09
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 111599987   158 CEPPPPISNGKHSGRDDDlYTFGSVVIYNCDPTFTLLGNASIVCTvvnrTVGVWRPHPPAC 218
Cdd:smart00032   1 CPPPPDIENGTVTSSSGT-YSYGDTVTYSCDPGYTLIGSSTITCL----ENGTWSPPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 223-278 9.90e-09

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 51.76  E-value: 9.90e-09
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 111599987   223 CHRPQIPKGYLAPGFRQFYAYRDALEIRCKKGFILRGSSVIHCEANGEWFPSIPTC 278
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 96-153 1.28e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 51.37  E-value: 1.28e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 111599987    96 CKNPGELVNGKVEIPSD-LLVGSIIEFSCSKGYLLIGSATSRCEVQGKgvdWSDSLPEC 153
Cdd:smart00032   1 CPPPPDIENGTVTSSSGtYSYGDTVTYSCDPGYTLIGSSTITCLENGT---WSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
158-218 4.65e-08

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 49.81  E-value: 4.65e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 111599987  158 CEPPPPISNGKHSGRDDDlYTFGSVVIYNCDPTFTLLGNASIVCTvvnrTVGVWRPHPPAC 218
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNE-YNYGASVSYECDPGYRLVGSPTITCQ----EDGTWSPPFPEC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
226-278 1.21e-07

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 48.65  E-value: 1.21e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 111599987  226 PQIPKGYLAPGfRQFYAYRDALEIRCKKGFILRGSSVIHCEANGEWFPSIPTC 278
Cdd:pfam00084   5 PDIPNGKVSAT-KNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 34-85 1.52e-07

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 48.23  E-value: 1.52e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 111599987  34 CGPPPLLPFASPTnqlYESTTFPSGTVLKYTCHHGFKRVNSSHLSCDENGSW 85
Cdd:cd00033    1 CPPPPVPENGTVT---GSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGW 49
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 456-510 4.99e-07

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 46.69  E-value: 4.99e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 111599987 456 CLKPMVI-NGNLSVERVIYAELENITIQCDPGYTIVGSPNIIC-SNRTWYPEVPSCQ 510
Cdd:cd00033    1 CPPPPVPeNGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCtENGGWSPPPPTCE 57
Sushi pfam00084
Sushi repeat (SCR repeat);
34-89 5.34e-07

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 46.72  E-value: 5.34e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 111599987   34 CGPPPLLPFASPTnqlYESTTFPSGTVLKYTCHHGFKRVNSSHLSCDENGSWVYST 89
Cdd:pfam00084   1 CPPPPDIPNGKVS---ATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPF 53
Sushi pfam00084
Sushi repeat (SCR repeat);
459-509 5.34e-07

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 46.72  E-value: 5.34e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 111599987  459 PMVINGNLSVERVIYAELENITIQCDPGYTIVGSPNIICS-NRTWYPEVPSC 509
Cdd:pfam00084   5 PDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQeDGTWSPPFPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 34-85 5.72e-07

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 46.75  E-value: 5.72e-07
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 111599987    34 CGPPPLLPFASPTnqlYESTTFPSGTVLKYTCHHGFKRVNSSHLSCDENGSW 85
Cdd:smart00032   1 CPPPPDIENGTVT---SSSGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTW 49
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 350-411 1.97e-06

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 45.21  E-value: 1.97e-06
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 111599987   350 CPTPDMEKIKIVSerrdfTGTCIYAYGDYVFYICNEGsYPMSTDGRSSCQADGKWDPAIPSC 411
Cdd:smart00032   1 CPPPPDIENGTVT-----SSSGTYSYGDTVTYSCDPG-YTLIGSSTITCLENGTWSPPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 456-509 2.57e-06

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 44.82  E-value: 2.57e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 111599987   456 CLKPMVI-NGNLSVERVIYAELENITIQCDPGYTIVGSPNIIC-SNRTWYPEVPSC 509
Cdd:smart00032   1 CPPPPDIeNGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITClENGTWSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
350-411 2.69e-06

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 44.80  E-value: 2.69e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 111599987  350 CPTP-DMEKIKIVSERRDftgtciYAYGDYVFYICNEGsYPMSTDGRSSCQADGKWDPAIPSC 411
Cdd:pfam00084   1 CPPPpDIPNGKVSATKNE------YNYGASVSYECDPG-YRLVGSPTITCQEDGTWSPPFPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 350-412 2.72e-06

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 44.76  E-value: 2.72e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 111599987 350 CPTPDMEKIKIVSERRDFtgtciYAYGDYVFYICNEGsYPMSTDGRSSCQADGKWDPAIPSCQ 412
Cdd:cd00033    1 CPPPPVPENGTVTGSKGS-----YSYGSTVTYSCNEG-YTLVGSSTITCTENGGWSPPPPTCE 57
PHA02817 PHA02817
EEV Host range protein; Provisional
 349-509 4.09e-06

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 48.01  E-value: 4.09e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 111599987 349 CCPTPDMEKIKIVSERRdftgtcIYAYGDYVFYICNEGS----YPMSTDGRSSCQADGKWDPAIPSCQadsglqnrLALF 424
Cdd:PHA02817  24 CCYPPSIKNGYIYNKKT------EYNIGSNVTFFCGNNTrgvrYTLVGEKNIICEKDGKWNKEFPVCK--------IIRC 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 111599987 425 TFPnisetnvtnktylfgheenstehamkgvCLKPMVINGNLSVERVIYAEleNITIQCDPGYTIVGSPNIICS-NRTWY 503
Cdd:PHA02817  90 RFP----------------------------ALQNGFVNGIPDSKKFYYES--EVSFSCKPGFVLIGTKYSVCGiNSSWI 139


                 ....*.
gi 111599987 504 PEVPSC 509
Cdd:PHA02817 140 PKVPIC 145
PHA02831 PHA02831
EEV host range protein; Provisional
 82-154 5.02e-06

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 48.45  E-value: 5.02e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 111599987  82 NGSWV-YSTFCARKRCKNPGeLVNGKVEI-PSDLLVGSIIEFSCSKGYLLIGSATSRCEVQGKgvdWSDSLPECV 154
Cdd:PHA02831 126 NKQWVpKYPVCKLIRCKYPA-LQNGFLNVfEKKFYYGDIVNFKCKKGFILLGSSVSTCDINSI---WYPGIPKCV 196
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 283-342 6.03e-06

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 43.61  E-value: 6.03e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 111599987 283 CTNIPDISYASWEGYKfplrnfEVFEIGAKLKYQCKPGYRasLNDPQTVTCQENLTWSST 342
Cdd:cd00033    1 CPPPPVPENGTVTGSK------GSYSYGSTVTYSCNEGYT--LVGSSTITCTENGGWSPP 52
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 58-167 2.63e-05

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 46.62  E-value: 2.63e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 111599987  58 GTVLKYTCHHGFKRVNSSHLSCDENgSWVYSTFCARKrCKNPgELVNGKVEiPSDLLVGSIIEFSCSKGYLLIGSATSRC 137
Cdd:PHA02954 150 GEHITINCDVGYEVIGASYISCTAN-SWNVIPSCQQK-CDIP-SLSNGLIS-GSTFSIGGVIHLSCKSGFTLTGSPSSTC 225

                         90       100       110
                 ....*....|....*....|....*....|
gi 111599987 138 eVQGKgvdWSDSLPECvIATCEPPPPISNG 167
Cdd:PHA02954 226 -IDGK---WNPVLPIC-VRSNEEFDPVDDG 250
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 283-342 2.68e-05

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 41.74  E-value: 2.68e-05
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 111599987   283 CTNIPDISYASWEGYKFPlrnfevFEIGAKLKYQCKPGYRasLNDPQTVTCQENLTWSST 342
Cdd:smart00032   1 CPPPPDIENGTVTSSSGT------YSYGDTVTYSCDPGYT--LIGSSTITCLENGTWSPP 52
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 350-512 1.56e-04

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 43.92  E-value: 1.56e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 111599987 350 CPTPDMEKIKIVSERRDFTGTciyaygDYVFYICNEGSYpmSTDGRSSCQADgKW---DPAIPSCQAD---SGLQNRlAL 423
Cdd:PHA02954  21 CTVPTMNNAKLTSTETSFNDK------QKVTFTCDSGYY--SLDPNAVCETD-KWkyeNPCKKMCTVSdyvSELYDK-PL 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 111599987 424 FTFPNISETNVTNKTYLFGHEE-------NSTEHAMKGVCLKPMVINGNLSVERVIYAELENITIQCDPGYTIVGSPNII 496
Cdd:PHA02954  91 YEVNSTITLICKDETKYFRCEEkngntswNDTVTCPNAECQPLQLEHGSCQPVKEKYSFGEHITINCDVGYEVIGASYIS 170

                        170
                 ....*....|....*.
gi 111599987 497 CSNRTWyPEVPSCQME 512
Cdd:PHA02954 171 CTANSW-NVIPSCQQK 185
PHA02817 PHA02817
EEV Host range protein; Provisional
 456-511 8.86e-04

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 41.08  E-value: 8.86e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 111599987 456 CLKPMVINGNLSVERVIYAELENITIQCDPG-----YTIVGSPNIICS-NRTWYPEVPSCQM 511
Cdd:PHA02817  25 CYPPSIKNGYIYNKKTEYNIGSNVTFFCGNNtrgvrYTLVGEKNIICEkDGKWNKEFPVCKI 86
PHA02831 PHA02831
EEV host range protein; Provisional
 307-415 3.74e-03

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 39.59  E-value: 3.74e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 111599987 307 FEIGAKLKYQCKPGY--RASLNDPQTVTCQeNLTWSSTNG-CERICCPTPDMEKIKIVSERRDFTgtciyaYGDYVFYIC 383
Cdd:PHA02831  96 YSFGDSVTYACKVNKleKYSIVGNETVKCI-NKQWVPKYPvCKLIRCKYPALQNGFLNVFEKKFY------YGDIVNFKC 168

                         90       100       110
                 ....*....|....*....|....*....|..
gi 111599987 384 NEGsYPMSTDGRSSCQADGKWDPAIPSCQADS 415
Cdd:PHA02831 169 KKG-FILLGSSVSTCDINSIWYPGIPKCVKDK 199
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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