NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|16421073|gb|AAL21423|]
View 

putative anaerobic dimethylsulfoxide reductase [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]

Protein Classification

DmsB/YnfG family anaerobic dimethyl sulfoxide reductase iron-sulfur subunit( domain architecture ID 11496220)

DmsB/YnfG family anaerobic dimethyl sulfoxide reductase iron-sulfur subunit is the electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds

Gene Ontology:  GO:0051539|GO:0046872|GO:0009061|GO:0009389

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
DMSO_dmsB TIGR02951
DMSO reductase, iron-sulfur subunit; This family consists of the iron-sulfur subunit, or chain ...
 14-175 6.26e-102

DMSO reductase, iron-sulfur subunit; This family consists of the iron-sulfur subunit, or chain B, of an enzyme called the anaerobic dimethyl sulfoxide reductase. Chains A and B are catalytic, while chain C is a membrane anchor.


:

Pssm-ID: 131996 [Multi-domain]  Cd Length: 161  Bit Score: 291.25  E-value: 6.26e-102
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073    14 QLGFFIDSSRCSGCKACQVACKDKNNLEVGRRFRRVYEVKGGSFIPTGQGgVSNNVFAYTLSISCNHCADPVCTKNCPTT 93
Cdd:TIGR02951   1 QYGFYVDQTRCSGCKTCQIACKDKNDLEVGVLFRRVYEYEGGGWTEEGEG-FHPDVFAYYISISCNHCADPACVKNCPTG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073    94 AMHKRPGDGIVRVDTDKCVGCGYCAWSCPYGAPQLNEQTGQMSKCDMCVDLLAKGEPPVCVATCPLEAIKFGPIDELRAK 173
Cdd:TIGR02951  80 AMYKREEDGLVLVDQDKCIGCRYCVWACPYGAPQYDPQQGVMGKCDGCYDRVEKGLRPACVDACPMRALDFGPIDELRAK 159


                  ..
gi 16421073   174 YG 175
Cdd:TIGR02951 160 YG 161
 
Name Accession Description Interval E-value
DMSO_dmsB TIGR02951
DMSO reductase, iron-sulfur subunit; This family consists of the iron-sulfur subunit, or chain ...
 14-175 6.26e-102

DMSO reductase, iron-sulfur subunit; This family consists of the iron-sulfur subunit, or chain B, of an enzyme called the anaerobic dimethyl sulfoxide reductase. Chains A and B are catalytic, while chain C is a membrane anchor.


Pssm-ID: 131996 [Multi-domain]  Cd Length: 161  Bit Score: 291.25  E-value: 6.26e-102
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073    14 QLGFFIDSSRCSGCKACQVACKDKNNLEVGRRFRRVYEVKGGSFIPTGQGgVSNNVFAYTLSISCNHCADPVCTKNCPTT 93
Cdd:TIGR02951   1 QYGFYVDQTRCSGCKTCQIACKDKNDLEVGVLFRRVYEYEGGGWTEEGEG-FHPDVFAYYISISCNHCADPACVKNCPTG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073    94 AMHKRPGDGIVRVDTDKCVGCGYCAWSCPYGAPQLNEQTGQMSKCDMCVDLLAKGEPPVCVATCPLEAIKFGPIDELRAK 173
Cdd:TIGR02951  80 AMYKREEDGLVLVDQDKCIGCRYCVWACPYGAPQYDPQQGVMGKCDGCYDRVEKGLRPACVDACPMRALDFGPIDELRAK 159


                  ..
gi 16421073   174 YG 175
Cdd:TIGR02951 160 YG 161
DMSOR_beta_like cd16371
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 16-165 5.48e-77

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319893 [Multi-domain]  Cd Length: 140  Bit Score: 227.45  E-value: 5.48e-77
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073  16 GFFIDSSRCSGCKACQVACKDKNNLEVGRRFRRVYEVKGGSFIptgqggvsnNVFAYTLSISCNHCADPVCTKNCPTTAM 95
Cdd:cd16371   1 GFYFDQERCIGCKACEIACKDKNDLPPGVNWRRVYEYEGGEFP---------EVFAYFLSMSCNHCENPACVKVCPTGAI 71

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073  96 HKRPgDGIVRVDTDKCVGCGYCAWSCPYGAPQLNEQTGQMSKCDMCVDLLAKGEPPVCVATCPLEAIKFG 165
Cdd:cd16371  72 TKRE-DGIVVVDQDKCIGCGYCVWACPYGAPQYNPETGKMDKCDMCVDRLDEGEKPACVAACPTRALDFG 140
HybA COG0437
Fe-S-cluster-containing dehydrogenase component (DMSO reductase) [Energy production and ...
 11-174 5.93e-70

Fe-S-cluster-containing dehydrogenase component (DMSO reductase) [Energy production and conversion];


Pssm-ID: 440206 [Multi-domain]  Cd Length: 184  Bit Score: 211.34  E-value: 5.93e-70
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073  11 SDKQLGFFIDSSRCSGCKACQVACKDKNNLEVGRRFRRVYEVKGGSFiptgqggvsNNVFAYTLSISCNHCADPVCTKNC 90
Cdd:COG0437   2 SMKRYGMVIDLTKCIGCRACVVACKEENNLPVGVTWRRVRRYEEGEF---------PNVEWLFVPVLCNHCDDPPCVKVC 72

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073  91 PTTAMHKRPgDGIVRVDTDKCVGCGYCAWSCPYGAPQLNEQTGQMSKCDMCVDLLAKGEPPVCVATCPLEAIKFGPIDEL 170
Cdd:COG0437  73 PTGATYKRE-DGIVLVDYDKCIGCRYCVAACPYGAPRFNPETGVVEKCTFCADRLDEGLLPACVEACPTGALVFGDLDDP 151


                ....
gi 16421073 171 RAKY 174
Cdd:COG0437 152 ESEV 155
PRK10882 PRK10882
hydrogenase 2 operon protein HybA;
9-172 9.71e-37

hydrogenase 2 operon protein HybA;


Pssm-ID: 236786 [Multi-domain]  Cd Length: 328  Bit Score: 130.56  E-value: 9.71e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073    9 PVSDKQLGFFIDSSRCSGCKACQVACKDKNNLEVGRRFRRVYE---------------VKGGSFIPTGQggvSNNVFAYt 73
Cdd:PRK10882  32 PPIPGALGMLYDSTLCVGCQACVTKCQEINFPERNPQGEQTWDnpdklspytnniikvWKSGTGVNKDQ---EENGYAY- 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073   74 LSISCNHCADPVCTKNCPTTAMHKRPGDGIVRVDTDKCVGCGYCAWSCPYGAP--QLNEQTGQMSKCDMC----VDLLAK 147
Cdd:PRK10882 108 IKKQCMHCVDPNCVSVCPVSALTKDPKTGIVHYDKDVCTGCRYCMVACPFNVPkyDYNNPFGAIHKCELCnqkgVERLDK 187

                        170       180
                 ....*....|....*....|....*
gi 16421073  148 GEPPVCVATCPLEAIKFGPIDELRA 172
Cdd:PRK10882 188 GGLPGCVEVCPTGAVIFGTREELLA 212
Fer4_11 pfam13247
4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to ...
 69-165 6.72e-27

4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contains two 4Fe4S clusters.


Pssm-ID: 404184 [Multi-domain]  Cd Length: 99  Bit Score: 98.47  E-value: 6.72e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073    69 VFAYTLSISCNHCADPVCTKNCPTTAMHKRPGDGIVRVDTDKCVGCGYCAWSCPYGAPQLNEQTGQMSKCDMCVDLLAKG 148
Cdd:pfam13247   1 VDWLFFPEQCRHCLNPPCKASCPVGAIYKDEETGAVLLDEKTCRGWRECVSACPYNIPRYNDETGKAEKCDMCYDRVEAG 80

                          90
                  ....*....|....*..
gi 16421073   149 EPPVCVATCPLEAIKFG 165
Cdd:pfam13247  81 LLPACVQTCPTGAMNFG 97
ferrodoxin_EFR1 NF038196
EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight ...
 108-165 5.94e-04

EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight conserved Cys residues in two CxxCxxCxxxCP motifs, each of which binds a 4Fe-4S cluster. The N-terminal region resembles flavodoxin domains, with some members of the family recognized by Pfam models PF12724 (Flavodoxin_5) or PF00258 (Flavodoxin_1).


Pssm-ID: 468407 [Multi-domain]  Cd Length: 243  Bit Score: 39.46  E-value: 5.94e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 16421073  108 TDKCVGCGYCAWSCPYGAPQLNEqtGQ---MSKCDMCvdlLAkgeppvCVATCPLEAIKFG 165
Cdd:NF038196 184 TDKCIGCGICAKVCPVNNIEMED--GKpvwGHNCTHC---LA------CIHRCPKEAIEYG 233
 
Name Accession Description Interval E-value
DMSO_dmsB TIGR02951
DMSO reductase, iron-sulfur subunit; This family consists of the iron-sulfur subunit, or chain ...
 14-175 6.26e-102

DMSO reductase, iron-sulfur subunit; This family consists of the iron-sulfur subunit, or chain B, of an enzyme called the anaerobic dimethyl sulfoxide reductase. Chains A and B are catalytic, while chain C is a membrane anchor.


Pssm-ID: 131996 [Multi-domain]  Cd Length: 161  Bit Score: 291.25  E-value: 6.26e-102
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073    14 QLGFFIDSSRCSGCKACQVACKDKNNLEVGRRFRRVYEVKGGSFIPTGQGgVSNNVFAYTLSISCNHCADPVCTKNCPTT 93
Cdd:TIGR02951   1 QYGFYVDQTRCSGCKTCQIACKDKNDLEVGVLFRRVYEYEGGGWTEEGEG-FHPDVFAYYISISCNHCADPACVKNCPTG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073    94 AMHKRPGDGIVRVDTDKCVGCGYCAWSCPYGAPQLNEQTGQMSKCDMCVDLLAKGEPPVCVATCPLEAIKFGPIDELRAK 173
Cdd:TIGR02951  80 AMYKREEDGLVLVDQDKCIGCRYCVWACPYGAPQYDPQQGVMGKCDGCYDRVEKGLRPACVDACPMRALDFGPIDELRAK 159


                  ..
gi 16421073   174 YG 175
Cdd:TIGR02951 160 YG 161
DMSOR_beta_like cd16371
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 16-165 5.48e-77

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319893 [Multi-domain]  Cd Length: 140  Bit Score: 227.45  E-value: 5.48e-77
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073  16 GFFIDSSRCSGCKACQVACKDKNNLEVGRRFRRVYEVKGGSFIptgqggvsnNVFAYTLSISCNHCADPVCTKNCPTTAM 95
Cdd:cd16371   1 GFYFDQERCIGCKACEIACKDKNDLPPGVNWRRVYEYEGGEFP---------EVFAYFLSMSCNHCENPACVKVCPTGAI 71

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073  96 HKRPgDGIVRVDTDKCVGCGYCAWSCPYGAPQLNEQTGQMSKCDMCVDLLAKGEPPVCVATCPLEAIKFG 165
Cdd:cd16371  72 TKRE-DGIVVVDQDKCIGCGYCVWACPYGAPQYNPETGKMDKCDMCVDRLDEGEKPACVAACPTRALDFG 140
HybA COG0437
Fe-S-cluster-containing dehydrogenase component (DMSO reductase) [Energy production and ...
 11-174 5.93e-70

Fe-S-cluster-containing dehydrogenase component (DMSO reductase) [Energy production and conversion];


Pssm-ID: 440206 [Multi-domain]  Cd Length: 184  Bit Score: 211.34  E-value: 5.93e-70
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073  11 SDKQLGFFIDSSRCSGCKACQVACKDKNNLEVGRRFRRVYEVKGGSFiptgqggvsNNVFAYTLSISCNHCADPVCTKNC 90
Cdd:COG0437   2 SMKRYGMVIDLTKCIGCRACVVACKEENNLPVGVTWRRVRRYEEGEF---------PNVEWLFVPVLCNHCDDPPCVKVC 72

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073  91 PTTAMHKRPgDGIVRVDTDKCVGCGYCAWSCPYGAPQLNEQTGQMSKCDMCVDLLAKGEPPVCVATCPLEAIKFGPIDEL 170
Cdd:COG0437  73 PTGATYKRE-DGIVLVDYDKCIGCRYCVAACPYGAPRFNPETGVVEKCTFCADRLDEGLLPACVEACPTGALVFGDLDDP 151


                ....
gi 16421073 171 RAKY 174
Cdd:COG0437 152 ESEV 155
PsrB cd10551
polysulfide reductase beta (PsrB) subunit; This family includes the beta subunit of bacterial ...
 19-168 2.69e-51

polysulfide reductase beta (PsrB) subunit; This family includes the beta subunit of bacterial polysulfide reductase (PsrABC), an integral membrane-bound enzyme responsible for quinone-coupled reduction of polysulfides, a process important in extreme environments such as deep-sea vents and hot springs. Polysulfide reductase contains three subunits: a catalytic subunit PsrA, an electron transfer PsrB subunit and the hydrophobic transmembrane PsrC subunit. PsrB belongs to the DMSO reductase superfamily that contains [4Fe-4S] clusters which transfer the electrons from the A subunit to the hydrophobic integral membrane C subunit via the B subunit. In Shewanella oneidensis, which has highly diverse anaerobic respiratory pathways, PsrABC is responsible for H2S generation as well as its regulation via respiration of sulfur species. PsrB transfers electrons from PsrC (serving as quinol oxidase) to the catalytic subunit PsrA for reduction of corresponding electron acceptors. It has been shown that T. thermophilus polysulfide reductase could be a key energy-conserving enzyme of the respiratory chain, using polysulfide as the terminal electron acceptor and pumping protons across the membrane.


Pssm-ID: 319873 [Multi-domain]  Cd Length: 185  Bit Score: 163.86  E-value: 2.69e-51
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073  19 IDSSRCSGCKACQVACKDKNNLEVGRRFRRVYEVKGGSFiptgqggvsNNVFAYTLSISCNHCADPVCTKNCPTTAMHKR 98
Cdd:cd10551   3 IDLRKCIGCGACVVACKAENNVPPGVFRNRVLEYEVGEY---------PNVKRTFLPVLCNHCENPPCVKVCPTGATYKR 73

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073  99 PgDGIVRVDTDKCVGCGYCAWSCPYGAPQLNEQ------------TGQMSKCDMCVDLLAKGEPPVCVATCPLEAIKFGP 166
Cdd:cd10551  74 E-DGIVLVDYDKCIGCRYCMAACPYGARYFNPEephefgevpvrpKGVVEKCTFCYHRLDEGLLPACVEACPTGARIFGD 152


                ..
gi 16421073 167 ID 168
Cdd:cd10551 153 LD 154
HybA_like cd10561
the FeS subunit of hydrogenase 2; This subfamily includes the beta-subunit of hydrogenase 2 ...
 16-172 2.93e-49

the FeS subunit of hydrogenase 2; This subfamily includes the beta-subunit of hydrogenase 2 (Hyd-2), an enzyme that catalyzes the reversible oxidation of H2 to protons and electrons. Hyd-2 is membrane-associated and forms an unusual heterotetrameric [NiFe]-hydrogenase in that it lacks the typical cytochrome b membrane anchor subunit that transfers electrons to the quinone pool. The electron transfer subunit of Hyd-2 (HybA) which is predicted to contain four iron-sulfur clusters, is essential for electron transfer from Hyd-2 to menaquinone/demethylmenaquinone (MQ/DMQ) to couple hydrogen oxidation to fumarate reduction.


Pssm-ID: 319883 [Multi-domain]  Cd Length: 196  Bit Score: 158.91  E-value: 2.93e-49
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073  16 GFFIDSSRCSGCKACQVACKDKNNLEVGR-RFRRVYEVKGG------SFIPTGQGGVSNNVFAYTlSISCNHCADPVCTK 88
Cdd:cd10561   1 GVLYDTTRCIGCRACEVACKEWNGLPAEDtAFGPGWDNPRDlsaktyTVIKRYEVETGGKGFVFV-KRQCMHCLDPACVS 79

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073  89 NCPTTAMHKRPgDGIVRVDTDKCVGCGYCAWSCPYGAPQL--NEQTGQMSKCDMCVDLLAKGEPPVCVATCPLEAIKFGP 166
Cdd:cd10561  80 ACPVGALRKTP-EGPVTYDEDKCIGCRYCMVACPFNIPKYewDSANPKIRKCTMCYDRLKEGKQPACVEACPTGALLFGK 158


                ....*.
gi 16421073 167 IDELRA 172
Cdd:cd10561 159 REELLA 164
DMSOR_beta-like cd04410
Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta ...
 17-165 8.27e-47

Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319870 [Multi-domain]  Cd Length: 136  Bit Score: 150.62  E-value: 8.27e-47
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073  17 FFIDSSRCSGCKACQVACKDKNNLEVGRRFRRVYEVKGGSfiptgqggvsnnVFAYTLSISCNHCADPVCTKNCPTTAMH 96
Cdd:cd04410   1 LVVDLDRCIGCGTCEVACKQEHGLRPGPDWSRIKVIEGGG------------LERAFLPVSCMHCEDPPCVKACPTGAIY 68

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 16421073  97 KRPgDGIVRVDTDKCVGCGYCAWSCPYGAPQLNEQTGQMSKCDMCVDLLAKGEPPVCVATCPLEAIKFG 165
Cdd:cd04410  69 KDE-DGIVLIDEDKCIGCGSCVEACPYGAIVFDPEPGKAVKCDLCGDRLDEGLEPACVKACPTGALTFG 136
PhsB_like cd10553
uncharacterized beta subfamily of DMSO Reductase similar to Desulfonauticus sp PhsB; This ...
 18-165 1.57e-43

uncharacterized beta subfamily of DMSO Reductase similar to Desulfonauticus sp PhsB; This family includes beta FeS subunits of anaerobic DMSO reductase (DMSOR) superfamily that have yet to be characterized. DMSOR consists of a large, periplasmic molybdenum-containing alpha subunit as well as a small beta FeS subunit, and may also have a small gamma subunit. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and the tungsten-containing formate dehydrogenase (FDH-T). Examples of heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319875 [Multi-domain]  Cd Length: 146  Bit Score: 142.89  E-value: 1.57e-43
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073  18 FIDSSRCSGCKACQVACKDKNNLEVGRRFRRVYEVKggsfiPTGQGGVSNNVFAYtlsISCNHCADPVCTKNCPTTAMHK 97
Cdd:cd10553   6 YHDSKRCIGCLACEVHCKVKNNLPVGPRLCRIFAVG-----PKMVGGKPRLKFVY---MSCFHCENPWCVKACPTGAMQK 77

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 16421073  98 RPGDGIVRVDTDKCVGCGYCAWSCPYGAPQLNEQTGQMSKCDMCVDLLAKGEPPVCVATCPLEAIKFG 165
Cdd:cd10553  78 REKDGIVYVDQELCIGCKACIEACPWGIPQWNPATGKVVKCDYCMDRIDQGLKPACVTGCTTHALSFV 145
FDH_b_like cd10562
uncharacterized subfamily of beta subunit of formate dehydrogenase; This subfamily includes ...
 18-170 4.73e-42

uncharacterized subfamily of beta subunit of formate dehydrogenase; This subfamily includes the beta-subunit of formate dehydrogenases that are as yet uncharacterized. Members of the DMSO reductase family include formate dehydrogenase N and O (FDH-N, FDH-O) and tungsten-containing formate dehydrogenase (W-FDH) and other similar proteins. FDH-N, a major component of nitrate respiration of Escherichia coli, is involved in the major anaerobic respiratory pathway in the presence of nitrate, catalyzing the oxidation of formate to carbon dioxide at the expense of nitrate reduction to nitrite. It forms a heterotrimer; the alpha-subunit (FDH-G) is the catalytic site of formate oxidation and membrane-associated, incorporating a selenocysteine (SeCys) residue and a [4Fe/4S] cluster in addition to two bis-MGD cofactors, the beta subunit (FDH-H) contains four [4Fe/4S] clusters which transfer the electrons from the alpha subunit to the gamma-subunit (FDH-I), a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. W-FDH contains a tungsten instead of molybdenum at the catalytic center. This enzyme seems to be exclusively found in organisms such as hyperthermophilic archaea that live in extreme environments. It is a heterodimer of a large and a small subunit; the large subunit harbors the W site and one [4Fe-4S] center and the small subunit, containing three [4Fe-4S] clusters, functions to transfer electrons.


Pssm-ID: 319884 [Multi-domain]  Cd Length: 161  Bit Score: 139.36  E-value: 4.73e-42
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073  18 FIDSSRCSGCKACQVACKDKNNLE-VGRRFRRVYEVKGG---------SFI--PTGQGGVSNNVFAYtlsiSCNHCADPV 85
Cdd:cd10562   2 LVDTSKCTACRGCQVACKQWNQLPaEKTPFTGSYQNPPDltpntwtliRFYehEEDNGGIRWLFRKR----QCMHCTDAA 77

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073  86 CTKNCPTTAMHKRPgDGIVRVDTDKCVGCGYCAWSCPYGAPQLNEQTGQMSKCDMCVDLLAKGEPPVCVATCPLEAIKFG 165
Cdd:cd10562  78 CVKVCPTGALYKTE-NGAVVVDEDKCIGCGYCVAACPFDVPRYDETTNKITKCTLCFDRIENGMQPACVKTCPTGALTFG 156


                ....*
gi 16421073 166 PIDEL 170
Cdd:cd10562 157 DRDEL 161
FDH_beta_like cd16366
beta FeS subunits of formate dehydrogenase N (FDH-N) and similar proteins; This family ...
 17-165 3.41e-41

beta FeS subunits of formate dehydrogenase N (FDH-N) and similar proteins; This family contains beta FeS subunits of several dehydrogenases in the DMSO reductase superfamily, including formate dehydrogenase N (FDH-N), tungsten-containing formate dehydrogenase (W-FDH) and other similar proteins. FDH-N is a major component of nitrate respiration of Escherichia coli; it catalyzes the oxidation of formate to carbon dioxide, donating the electrons to a second substrate to a cytochrome. W-FDH contains a tungsten instead of molybdenum at the catalytic center and seems to be exclusively found in organisms such as hyperthermophilic archaea that live in extreme environments. It catalyzes the oxidation of formate to carbon dioxide, donating the electrons to a second substrate.


Pssm-ID: 319888 [Multi-domain]  Cd Length: 156  Bit Score: 137.15  E-value: 3.41e-41
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073  17 FFIDSSRCSGCKACQVACKDKNNLEVGR-RFRRVYEVKGG-----------SFIPTGQGGVSNNVFaytlSISCNHCADP 84
Cdd:cd16366   1 FLVDTSRCTGCRACQVACKQWNGLPAEKtEFTGSYQNPPDltahtwtlvrfYEVEKPGGDLSWLFR----KDQCMHCTDA 76

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073  85 VCTKNCPTTAMHKRPGdGIVRVDTDKCVGCGYCAWSCPYGAPQLNEQTGQMSKCDMCVDLLAKGEPPVCVATCPLEAIKF 164
Cdd:cd16366  77 GCLAACPTGAIIRTET-GTVVVDPETCIGCGYCVNACPFDIPRFDEETGRVAKCTLCYDRISNGLQPACVKTCPTGALTF 155


                .
gi 16421073 165 G 165
Cdd:cd16366 156 G 156
FDH-O_like cd10560
beta subunit of formate dehydrogenase O (FDH-O) and similar proteins; This subfamily includes ...
 16-173 1.90e-40

beta subunit of formate dehydrogenase O (FDH-O) and similar proteins; This subfamily includes beta subunit of formate dehydrogenase family O (FDH-O), which is highly homologous to formate dehydrogenase N (FDH-N), a member of the DMSO reductase family. In E. coli three formate dehydrogenases are synthesized that are capable of oxidizing formate; Fdh-H, couples formate disproportionation to hydrogen and CO2, and is part of the cytoplasmically oriented formate hydrogenlyase complex, while FDH-N and FDH-O indicate their respective induction after growth with nitrate and oxygen. Little is known about FDH-O, although it shows formate oxidase activity during aerobic growth and is also synthesized during nitrate respiration, similar to FDH-N.


Pssm-ID: 319882 [Multi-domain]  Cd Length: 225  Bit Score: 137.52  E-value: 1.90e-40
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073  16 GFFIDSSRCSGCKACQVACKDKNNLEV-GRRF-RRVYEVKGG---------SFI--PTGQGGVSNNVFAYTL--SISCNH 80
Cdd:cd10560   1 GFFTDTSICIGCKACEVACKQWNQLPAdGYDFsGMSYDNTGDlsastwrhvKFIerPTEDGPANEGGDLQWLfmSDVCKH 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073  81 CADPVCTKNCPTTAMHKRPGDGIVrVDTDKCVGCGYCAWSCPYGAPQLNEQTGQMSKCDMCVDLLAKGEPPVCVATCPLE 160
Cdd:cd10560  81 CTDAGCLEACPTGAIFRTEFGTVY-IQPDICNGCGYCVAACPFGVIDRNEETGRAHKCTLCYDRLKDGLEPACAKACPTG 159

                       170
                ....*....|...
gi 16421073 161 AIKFGPIDELRAK 173
Cdd:cd10560 160 SIQFGPLEELRER 172
DMSOR_beta_like cd16374
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 18-173 4.72e-37

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319896 [Multi-domain]  Cd Length: 139  Bit Score: 125.85  E-value: 4.72e-37
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073  18 FIDSSRCSGCKACQVACKDKNNlevGRRFRRVYEVKGGSFIPtgqggvsnnvfaytlsISCNHCADPVCTKNCPTTAMHk 97
Cdd:cd16374   2 YVDPERCIGCRACEIACAREHS---GKPRISVEVVEDLASVP----------------VRCRHCEDAPCMEVCPTGAIY- 61

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 16421073  98 RPGDGIVRVDTDKCVGCGYCAWSCPYGAPQLNEQTGQMSKCDMCVDLLAKGEPPVCVATCPLEAIKFGPIDELRAK 173
Cdd:cd16374  62 RDEDGAVLVDPDKCIGCGMCAMACPFGVPRFDPSLKVAVKCDLCIDRRREGKLPACVEACPTGALKFGDIEELLKE 137
PRK10882 PRK10882
hydrogenase 2 operon protein HybA;
9-172 9.71e-37

hydrogenase 2 operon protein HybA;


Pssm-ID: 236786 [Multi-domain]  Cd Length: 328  Bit Score: 130.56  E-value: 9.71e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073    9 PVSDKQLGFFIDSSRCSGCKACQVACKDKNNLEVGRRFRRVYE---------------VKGGSFIPTGQggvSNNVFAYt 73
Cdd:PRK10882  32 PPIPGALGMLYDSTLCVGCQACVTKCQEINFPERNPQGEQTWDnpdklspytnniikvWKSGTGVNKDQ---EENGYAY- 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073   74 LSISCNHCADPVCTKNCPTTAMHKRPGDGIVRVDTDKCVGCGYCAWSCPYGAP--QLNEQTGQMSKCDMC----VDLLAK 147
Cdd:PRK10882 108 IKKQCMHCVDPNCVSVCPVSALTKDPKTGIVHYDKDVCTGCRYCMVACPFNVPkyDYNNPFGAIHKCELCnqkgVERLDK 187

                        170       180
                 ....*....|....*....|....*
gi 16421073  148 GEPPVCVATCPLEAIKFGPIDELRA 172
Cdd:PRK10882 188 GGLPGCVEVCPTGAVIFGTREELLA 212
CooF_like cd10563
CooF, iron-sulfur subunit of carbon monoxide dehydrogenase; This family includes CooF, the ...
 18-165 3.30e-34

CooF, iron-sulfur subunit of carbon monoxide dehydrogenase; This family includes CooF, the iron-sulfur subunit of carbon monoxide dehydrogenase (CODH), found in anaerobic bacteria and archaea. Carbon monoxide dehydrogenase is a key enzyme for carbon monoxide (CO) metabolism, where CooF is the proposed mediator of electron transfer between CODH and the CO-induced hydrogenase, catalyzing the reaction that uses CO as a single carbon and energy source, and producing only H2 and CO2. The ion-sulfur subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons in the protein complex during reaction.


Pssm-ID: 319885 [Multi-domain]  Cd Length: 140  Bit Score: 118.51  E-value: 3.30e-34
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073  18 FIDSSRCSGCKACQVAC-----------KDKNNLEVGRRFRRVYEVKGGSFiptgqggvsnnvfaytlSISCNHCADPVC 86
Cdd:cd10563   3 FIDEEKCLGCKLCEVACavahskskdliKAKLEKERPRPRIRVEESGGRSF-----------------PLQCRHCDEPPC 65

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 16421073  87 TKNCPTTAMHKRPGDGIVRVDTDKCVGCGYCAWSCPYGAPQLNEQTGQMSKCDMCVDLlakgEPPVCVATCPLEAIKFG 165
Cdd:cd10563  66 VKACMSGAMHKDPETGIVIHDEEKCVGCWMCVMVCPYGAIRPDKERKVALKCDLCPDR----ETPACVEACPTGALVLE 140
FDH-N cd10558
The beta FeS subunit of formate dehydrogenase-N (FDH-N); This subfamily contains beta FeS ...
 19-172 1.19e-33

The beta FeS subunit of formate dehydrogenase-N (FDH-N); This subfamily contains beta FeS subunit of formate dehydrogenase-N (FDH-N), a member of the DMSO reductase family. FDH-N is involved in the major anaerobic respiratory pathway in the presence of nitrate, catalyzing the oxidation of formate to carbon dioxide at the expense of nitrate reduction to nitrite. Thus, FDH-N is a major component of nitrate respiration of Escherichia coli. This integral membrane enzyme forms a heterotrimer; the alpha-subunit (FDH-G) is the catalytic site of formate oxidation and membrane-associated, incorporating a selenocysteine (SeCys) residue and a [4Fe/4S] cluster in addition to two bis-MGD cofactors, the beta subunit (FDH-H) contains four [4Fe/4S] clusters which transfer the electrons from the alpha subunit to the gamma-subunit (FDH-I), a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups.


Pssm-ID: 319880 [Multi-domain]  Cd Length: 208  Bit Score: 119.41  E-value: 1.19e-33
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073  19 IDSSRCSGCKACQVACKDKNNL--EVGR-------------------RFRRVYEVKGGSFIPTGQGgvsnnvfaytlsis 77
Cdd:cd10558   4 IDVSKCIGCKACQVACKEWNDLraEVGHnvgtyqnpadlspetwtlmKFREVEDNGKLEWLIRKDG-------------- 69

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073  78 CNHCADPVCTKNCPTTAMHKRPGDGIVRVDTDKCVGCGYCAWSCPYGAPQLNEQTGQMSKCDMCVDLLAKGEPPVCVATC 157
Cdd:cd10558  70 CMHCADPGCLKACPSPGAIVQYANGIVDFQSDKCIGCGYCIKGCPFDIPRISKDDNKMYKCTLCSDRVSVGLEPACVKTC 149

                       170
                ....*....|....*
gi 16421073 158 PLEAIKFGPIDELRA 172
Cdd:cd10558 150 PTGALHFGTKEDMLA 164
DMSOR_beta_like cd16369
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 17-173 3.38e-31

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319891 [Multi-domain]  Cd Length: 172  Bit Score: 112.10  E-value: 3.38e-31
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073  17 FFIDSSRCSGCKACQVACKdknnlEVGrrfrrvyevkggsfiptGQGGVSNNVFAY--------TLSISCNHCADPVCTK 88
Cdd:cd16369   4 FFIDPSRCIGCRACVAACR-----ECG-----------------THRGKSMIHVDYidrgestqTAPTVCMHCEDPTCAE 61

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073  89 NCPTTAMhKRPGDGIVR-VDTDKCVGCGYCAWSCPYGAPQLNEQTGQMSKCDMCVDLLAKGEPPVCVATCPLEAIKFGPI 167
Cdd:cd16369  62 VCPADAI-KVTEDGVVQsALKPRCIGCSNCVNACPFGVPKYDEERNLMMKCDMCYDRTSVGKAPMCASVCPSGALFYGTR 140


                ....*.
gi 16421073 168 DELRAK 173
Cdd:cd16369 141 EEIQAL 146
EBDH_beta cd10555
beta subunit of ethylbenzene-dehydrogenase (EBDH); This subfamily includes ethylbenzene ...
 11-169 7.58e-30

beta subunit of ethylbenzene-dehydrogenase (EBDH); This subfamily includes ethylbenzene dehydrogenase (EBDH, EC 1.17.99.2), a member of the DMSO reductase family. EBDH oxidizes the hydrocarbon ethylbenzene to (S)-1-phenylethanol. It is a heterotrimer, with the alpha subunit containing the catalytic center with a molybdenum held by two molybdopterin-guanine dinucleotides, the beta subunit containing four iron-sulfur clusters (the electron transfer subunit) and the gamma subunit containing a methionine and a lysine as axial heme ligands. During catalysis, electrons produced by substrate oxidation are transferred to a heme in the gamma subunit and then presumably to a separate cytochrome involved in nitrate respiration.


Pssm-ID: 319877 [Multi-domain]  Cd Length: 316  Bit Score: 112.01  E-value: 7.58e-30
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073  11 SDKQLGFFIDSSRCSGCKACQVACKDK------------NNLEV--GRRFRRVYEVKGGSF----------IPT------ 60
Cdd:cd10555   1 SKRQLAMVMDLNKCIGCQTCTVACKTLwtnrngreymywNNVETqpGKGYPKNWEKKGGGFkdkgelkpgiIPTledygv 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073  61 ------------------------------------GQGGVSNNVFAYTLSIsCNHCADPVCTKNCPTTAMHKRPGDGIV 104
Cdd:cd10555  81 pweynheeelfegkggrvrpspkgdptwgpnwdedqGAGEYPNSYYFYLPRI-CNHCTNPACLAACPRKAIYKREEDGIV 159

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 16421073 105 RVDTDKCVGCGYCAWSCPYGAPQLNEQTGQMSKCDMCVDLLAKGEPPVCVATCPLEAIKFGPIDE 169
Cdd:cd10555 160 LVDQDRCRGYRYCVEACPYKKIYFNPVEQKSEKCIFCYPRIEKGVAPACARQCVGRIRFVGYLDD 224
PRK14993 PRK14993
tetrathionate reductase subunit TtrB;
11-157 1.76e-29

tetrathionate reductase subunit TtrB;


Pssm-ID: 184955 [Multi-domain]  Cd Length: 244  Bit Score: 109.58  E-value: 1.76e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073   11 SDKQLGFFIDSSRCSGCKACQVACKDKNNLEVGRrFR---RVYEVKggsfiPTGQGGVsNNVFAYTLsisCNHCADPVCT 87
Cdd:PRK14993  40 PRHRYAMLIDLRRCIGCQSCTVSCTIENQTPQGA-FRttvNQYQVQ-----REGSQEV-TNVLLPRL---CNHCDNPPCV 109

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073   88 KNCPTTAMHKRPgDGIVRVDTDKCVGCGYCAWSCPYGAPQLNEQTGQMSKCDMCVDLLAKGEPPVCVATC 157
Cdd:PRK14993 110 PVCPVQATFQRE-DGIVVVDNKRCVGCAYCVQACPYDARFINHETQTADKCTFCVHRLEAGLLPACVESC 178
DMSOR_beta_like cd10550
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 19-164 2.09e-29

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319872 [Multi-domain]  Cd Length: 130  Bit Score: 106.12  E-value: 2.09e-29
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073  19 IDSSRCSGCKACQVACKDKNNLEVGRRFRRVYEVKggsfipTGQGGVSNNVFaytlsisCNHCADPVCTKNCPTTAMHKR 98
Cdd:cd10550   3 VDPEKCTGCRTCELACSLKHEGVFNPSLSRIRVVR------FEPEGLDVPVV-------CRQCEDAPCVEACPVGAISRD 69

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 16421073  99 PGDGIVRVDTDKCVGCGYCAWSCPYGAPQLNEQTGQMSKCDMCvdllaKGEpPVCVATCPLEAIKF 164
Cdd:cd10550  70 EETGAVVVDEDKCIGCGMCVEACPFGAIRVDPETGKAIKCDLC-----GGD-PACVKVCPTGALEF 129
TH_beta_N cd10552
N-terminal FeS domain of pyrogallol-phloroglucinol transhydroxylase (TH), beta subunit; This ...
 17-169 1.54e-27

N-terminal FeS domain of pyrogallol-phloroglucinol transhydroxylase (TH), beta subunit; This family includes the beta subunit of pyrogallol-phloroglucinol transhydroxylase (TH), a cytoplasmic molybdenum (Mo) enzyme from anaerobic microorganisms like Pelobacter acidigallici and Desulfitobacterium hafniense which catalyzes the conversion of pyrogallol to phloroglucinol, an important building block of plant polymers. TH belongs to the DMSO reductase (DMSOR) family; it is a heterodimer consisting of a large alpha catalytic subunit and a small beta FeS subunit. The beta subunit has two domains with the N-terminal domain containing three [4Fe-4S] centers and a seven-stranded, mainly antiparallel beta-barrel domain. In the anaerobic bacterium Pelobacter acidigallici, gallic acid, pyrogallol, phloroglucinol, or phloroglucinol carboxylic acid are fermented to three molecules of acetate (plus CO2), and TH is the key enzyme in the fermentation pathway, which converts pyrogallol to phloroglucinol in the absence of O2.


Pssm-ID: 319874 [Multi-domain]  Cd Length: 186  Bit Score: 102.79  E-value: 1.54e-27
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073  17 FFIDSSRCSGCKACQVACKD-----------KNNLEVGRRFRRVYEVKggsfiptgQGGVSNNVFAYtLSISCNHCADPV 85
Cdd:cd10552   1 LVIDVAKCNGCYNCFLACKDehvgndwpgyaAPQPRHGHFWMRILRRE--------RGQYPKVDVAY-LPVPCNHCDNAP 71

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073  86 CTKNCPTTAMHKRPgDGIVRVDTDKCVGCGYCAWSCPYGAPQLNEQTGQMSKCDMCVDLLAKGEP-PVCVATCPLEAIKF 164
Cdd:cd10552  72 CIKAAKDGAVYKRD-DGIVIIDPEKAKGQKQLVDACPYGAIYWNEELQVPQKCTFCAHLLDDGWKePRCVQACPTGALRF 150


                ....*
gi 16421073 165 GPIDE 169
Cdd:cd10552 151 GKLED 155
NarH_like cd16365
beta FeS subunits DMSOR NarH-like family; This subfamily contains beta FeS subunits of several ...
 13-169 4.99e-27

beta FeS subunits DMSOR NarH-like family; This subfamily contains beta FeS subunits of several DMSO reductase superfamily, including nitrate reductase A, ethylbenzene dehydrogenase and selenate reductase. DMSO Reductase (DMSOR) family members have a large, periplasmic molybdenum-containing alpha subunit as well as a small beta FeS subunit, and may also have a small gamma subunit. . The beta subunits of DMSOR contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system. Nitrate reductase A contains three subunits (the catalytic subunit NarG, the catalytic subunit NarH with four [Fe-S] clusters, and integral membrane subunit NarI) and often forms a respiratory chain with the formate dehydrogenase via the lipid soluble quinol pool. Ethylbenzene dehydrogenase oxidizes the hydrocarbon ethylbenzene to (S)-1-phenylethanol. Selenate reductase catalyzes reduction of selenate to selenite in bacterial species that can obtain energy by respiring anaerobically with selenate as the terminal electron acceptor.


Pssm-ID: 319887 [Multi-domain]  Cd Length: 201  Bit Score: 101.89  E-value: 4.99e-27
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073  13 KQLGFFIDSSRCSGCKACQVACKDK------------NNLEV--GRRFRRVYEVKggsfipTGQGGvSNNVFAYTLSISC 78
Cdd:cd16365   1 KQFAAVFNLNKCIGCQTCTVACKNAwtyrkgqeymwwNNVETkpGGGYPQDWEVK------TIDNG-GNTRFFFYLQRLC 73

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073  79 NHCADPVCTKNCPTTAMHKRPGDGIVRVDTDKCVGCGYCAWSCPYGAPQLNEQTGQMSKCDMCVDLLAKGEPPVCVATCP 158
Cdd:cd16365  74 NHCTNPACLAACPRGAIYKREEDGIVLIDQKRCRGYRKCVEQCPYKKIYFNGLSRVSEKCIACYPRIEGGDPTRCMSACV 153

                       170
                ....*....|.
gi 16421073 159 LEAIKFGPIDE 169
Cdd:cd16365 154 GRIRLQGFLDD 164
Fer4_11 pfam13247
4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to ...
 69-165 6.72e-27

4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contains two 4Fe4S clusters.


Pssm-ID: 404184 [Multi-domain]  Cd Length: 99  Bit Score: 98.47  E-value: 6.72e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073    69 VFAYTLSISCNHCADPVCTKNCPTTAMHKRPGDGIVRVDTDKCVGCGYCAWSCPYGAPQLNEQTGQMSKCDMCVDLLAKG 148
Cdd:pfam13247   1 VDWLFFPEQCRHCLNPPCKASCPVGAIYKDEETGAVLLDEKTCRGWRECVSACPYNIPRYNDETGKAEKCDMCYDRVEAG 80

                          90
                  ....*....|....*..
gi 16421073   149 EPPVCVATCPLEAIKFG 165
Cdd:pfam13247  81 LLPACVQTCPTGAMNFG 97
DMSOR_beta_like cd16368
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 78-173 5.37e-26

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319890 [Multi-domain]  Cd Length: 200  Bit Score: 99.42  E-value: 5.37e-26
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073  78 CNHCADPVCTKNCPTTAMHKRPgDGIVRVDTDKCVGCGYCAWSCPYGAPQLNEQTG-------------QMSKCDMCVDL 144
Cdd:cd16368  91 CMHCDNPPCAKLCPFGAARKTP-EGAVYIDDDLCFGGAKCRDVCPWHIPQRQAGVGiylhlapeyagggVMYKCDLCKDL 169

                        90       100
                ....*....|....*....|....*....
gi 16421073 145 LAKGEPPVCVATCPLEAIKFGPIDELRAK 173
Cdd:cd16368 170 LAQGKPPACIEACPKGAQYFGPRKEMVAL 198
cyt_nit_nrfC TIGR03149
cytochrome c nitrite reductase, Fe-S protein; Members of this protein family are the Fe-S ...
 13-169 6.17e-25

cytochrome c nitrite reductase, Fe-S protein; Members of this protein family are the Fe-S protein, NrfC, of a cytochrome c nitrite reductase system for which the pentaheme cytochrome c protein, NrfB (family TIGR03146) is an unambiguous marker. Members of this protein family show similarity to other ferredoxin-like proteins, including a subunit of a polysulfide reductase. [Energy metabolism, Electron transport]


Pssm-ID: 274451 [Multi-domain]  Cd Length: 225  Bit Score: 97.16  E-value: 6.17e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073    13 KQLGFFIDSSRCSGCKACQVACKDKNNLEVGrrfrrvyeVKGGSFIPTGQGGVSNNVFAYTLSISCNHCADPVCTKNCPT 92
Cdd:TIGR03149  37 KRYGMVHDETACIGCTACMDACREVNKVPEG--------VSRLEIIRSEPYGEFPDVEYRFFRKSCQHCDNAPCVAVCPT 108

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 16421073    93 TAMHKRPGDGIVRVDTDKCVGCGYCAWSCPYGAPQLNEQTGQMSKCDMCVDL-LAKGEPPVCVATCPLEAIKFGPIDE 169
Cdd:TIGR03149 109 GASFKDEETGIVDVHKDLCVGCQYCIAACPYRVRFIHPVTKSADKCNFCRDTnLAEGKLPACVESCPTKALTFGDLND 186
W-FDH cd10559
tungsten-containing formate dehydrogenase, small subunit; This subfamily contains beta subunit ...
 16-172 5.89e-24

tungsten-containing formate dehydrogenase, small subunit; This subfamily contains beta subunit of Tungsten-containing formate dehydrogenase (W-FDH), a member of the DMSO reductase family. W-FDH contains a tungsten instead of molybdenum at the catalytic center. This enzyme seems to be exclusively found in organisms such as hyperthermophilic archaea that live in extreme environments. It is a heterodimer of a large and a small subunit; the large subunit harbors the W site and one [4Fe-4S] center and the small subunit, containing three [4Fe-4S] clusters, functions to transfer electrons.


Pssm-ID: 319881 [Multi-domain]  Cd Length: 200  Bit Score: 94.04  E-value: 5.89e-24
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073  16 GFFIDSSRCSGCKACQVACKDKNNLEV----------------GRRFRRV--YEVKggsfipTGQGGVSNNVFaytlSIS 77
Cdd:cd10559   1 SFLIDTTRCTACRGCQVACKQWNQLPAeqtkntgshqnppdlsANTYKLVrfNEVR------NENGKPDWLFF----PDQ 70

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073  78 CNHCADPVCTKNCPTT--AMHKRPGDGIVrVDTDKCVGCGYCAW--SCPYGAPQLNEQTGQMSKCDMCVDLLAKGEPPVC 153
Cdd:cd10559  71 CRHCVTPPCKDAADMVpgAVIQDEATGAV-VFTEKTAELDFDDVlsACPYNIPRKNEATGRIVKCDMCIDRVSNGLQPAC 149

                       170
                ....*....|....*....
gi 16421073 154 VATCPLEAIKFGPIDELRA 172
Cdd:cd10559 150 VKACPTGAMNFGDRDEMLA 168
NarH_beta-like cd10557
beta subunit of nitrate reductase A (NarH) and similar proteins; This subfamily includes ...
 68-157 3.00e-23

beta subunit of nitrate reductase A (NarH) and similar proteins; This subfamily includes nitrate reductase A, a member of the DMSO reductase family. The respiratory nitrate reductase complex (NarGHI) from E. coli is a heterotrimer, with the catalytic subunit (NarG) with a molybdo-bis (molybdopterin guanine dinucleotide) cofactor and an [Fe-S] cluster, the electron transfer subunit (NarH) with four [Fe-S] clusters, and the integral membrane subunit (NarI) with two b-type hemes. Nitrate reductase A often forms a respiratory chain with the formate dehydrogenase via the lipid soluble quinol pool. Electron transfer from formate to nitrate is coupled to proton translocation across the cytoplasmic membrane generating proton motive force by a redox loop mechanism. Demethylmenaquinol (DMKH2) has been shown to be a good substrate for NarGHI in nitrate respiration in E. coli.


Pssm-ID: 319879 [Multi-domain]  Cd Length: 363  Bit Score: 95.12  E-value: 3.00e-23
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073  68 NVFAYTLSISCNHCADPVCTKNCPTTAMHKRPGDGIVRVDTDKCVGCGYCAWSCPYGAPQLNEQTGQMSKCDMCVDLLAK 147
Cdd:cd10557 169 NTFMFYLPRICNHCLNPACVAACPSGAIYKREEDGIVLIDQDRCRGWRMCVSACPYKKVYYNWKTGKSEKCIFCYPRLEA 248

                        90
                ....*....|
gi 16421073 148 GEPPVCVATC 157
Cdd:cd10557 249 GQPTVCSETC 258
HycB COG1142
Fe-S-cluster-containing hydrogenase component 2 [Energy production and conversion];
19-164 4.19e-23

Fe-S-cluster-containing hydrogenase component 2 [Energy production and conversion];


Pssm-ID: 440757 [Multi-domain]  Cd Length: 138  Bit Score: 90.10  E-value: 4.19e-23
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073  19 IDSSRCSGCKACQVACKDKNNLEVGRRFR-RVYEVKGGSFiptgqggvsnnvfayTLSISCNHCADPVCTKNCPTTAMHK 97
Cdd:COG1142   7 ADPEKCIGCRTCEAACAVAHEGEEGEPFLpRIRVVRKAGV---------------SAPVQCRHCEDAPCAEVCPVGAITR 71

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 16421073  98 RpgDGIVRVDTDKCVGCGYCAWSCPYGAPQLNEQTGQM--SKCDMCVDllaKGEPPVCVATCPLEAIKF 164
Cdd:COG1142  72 D--DGAVVVDEEKCIGCGLCVLACPFGAITMVGEKSRAvaVKCDLCGG---REGGPACVEACPTGALRL 135
HycB_like cd10554
HycB, HydN and similar proteins; This family includes HycB, the FeS subunit of a ...
 20-164 9.59e-22

HycB, HydN and similar proteins; This family includes HycB, the FeS subunit of a membrane-associated formate hydrogenlyase system (FHL-1) in Escherichia coli that breaks down formate, produced during anaerobic fermentation, to H2 and CO2. FHL-1 consists of formate dehydrogenase H (FDH-H) and the hydrogenase 3 complex (Hyd-3). HycB is thought to code for the [4Fe-4S] ferredoxin subunit of hydrogenase 3, which functions as an intermediate electron carrier protein between hydrogenase 3 and formate dehydrogenase. HydN codes for the [4Fe-4S] ferredoxin subunit of FDH-H; a hydN in-frame deletion mutation causes only weak reduction in hydrogenase activity, but loss of more than 60% of FDH-H activity. This pathway is only active at low pH and high formate concentrations, and is thought to provide a detoxification/de-acidification system countering the buildup of formate during fermentation.


Pssm-ID: 319876 [Multi-domain]  Cd Length: 149  Bit Score: 86.93  E-value: 9.59e-22
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073  20 DSSRCSGCKACQVAC----KDKNNLEVGRR----FRRVYEVKGGSFiptgqggvsnnvfayTLSISCNHCADPVCTKNCP 91
Cdd:cd10554   5 DPDKCIGCRTCEVACaaahSGKGIFEAGTDglpfLPRLRVVKTGEV---------------TAPVQCRQCEDAPCANVCP 69

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073  92 TTAMHKrpGDGIVRVDTDKCVGCGYCAWSCPYGAPQLNEQT-----------GQMSKCDMCVDllaKGEPPVCVATCPLE 160
Cdd:cd10554  70 VGAISQ--EDGVVQVDEERCIGCKLCVLACPFGAIEMAPTTvpgvdwergprAVAVKCDLCAG---REGGPACVEACPTK 144


                ....
gi 16421073 161 AIKF 164
Cdd:cd10554 145 ALTL 148
PRK09898 PRK09898
ferredoxin-like protein;
22-170 1.28e-20

ferredoxin-like protein;


Pssm-ID: 182135 [Multi-domain]  Cd Length: 208  Bit Score: 85.27  E-value: 1.28e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073   22 SRCSGCKACQVACKDKNNLEVGRRFRRVYEVKGGSFIPTG---QGGVSNNvFAYTLSiSCNHCADPVCTKNCPTTAMHKR 98
Cdd:PRK09898  66 ARCTGCHRCEISCTNFNDGSVGTFFSRIKIHRNYFFGDNGvgsGGGLYGD-LNYTAD-TCRQCKEPQCMNVCPIGAITWQ 143

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 16421073   99 PGDGIVRVDTDKCVGCGYCAWSCPYGAPQLNEQTGQMSKCDMCvdllakGEppvCVATCPLEAIKFGPIDEL 170
Cdd:PRK09898 144 QKEGCITVDHKRCIGCSACTTACPWMMATVNTESKKSSKCVLC------GE---CANACPTGALKIIEWKDI 206
NarY COG1140
Nitrate reductase beta subunit [Energy production and conversion, Inorganic ion transport and ...
 78-157 4.65e-20

Nitrate reductase beta subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440755 [Multi-domain]  Cd Length: 485  Bit Score: 87.17  E-value: 4.65e-20
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073  78 CNHCADPVCTKNCPTTAMHKRPGDGIVRVDTDKCVGCGYCAWSCPYGAPQLNEQTGQMSKCDMCVDLLAKGEPPVCVATC 157
Cdd:COG1140 182 CEHCLNPACVASCPSGAIYKREEDGIVLVDQDKCRGWRMCVSGCPYKKVYFNWKTGKAEKCIFCYPRIEAGQPTVCSETC 261
SER_beta cd10556
Beta subunit of selenate reductase; This subfamily includes beta FeS subunit of selenate ...
 12-158 5.21e-20

Beta subunit of selenate reductase; This subfamily includes beta FeS subunit of selenate reductase (SER), a member of the DMSO reductase family. SER catalyzes the reduction of selenate to selenite in bacterial species that can obtain energy by respiring anaerobically with selenate as the terminal electron acceptor. The enzyme comprises three subunits SerABC, forming a heterotrimer, with the catalytic component (alpha-subunit), iron-sulfur protein (beta-subunit) and monomeric b-type heme-containing gamma subunit. Beta subunit contains coordinating one [3Fe-4S] cluster and three [4Fe-4S] clusters and functions as electron carrier.


Pssm-ID: 319878 [Multi-domain]  Cd Length: 287  Bit Score: 85.20  E-value: 5.21e-20
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073  12 DKQLGFFIDSSRCSGCKACQVACKDK------------NNLE--------VGRRFRRVYEVKGGS--------------- 56
Cdd:cd10556   9 DKQFAMVFDTNKCIACQTCTMACKSTwtsgkgqeymwwNNVEtkpyggypLGWDVRLLDEEGGQTwaeggvyegktifea 88

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073  57 ---------FIPTGQGGVSNNVFA----------------------YTLSISCNHCADPVCTKNCPTTAMHKRPGDGIVR 105
Cdd:cd10556  89 aaageqvlgYRPEDEDWRYPNIGEdevngertpdtgsslpphpiwfFYLPRICNHCTYPACLAACPRKAIYKREEDGIVL 168

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|...
gi 16421073 106 VDTDKCVGCGYCAWSCPYGAPQLNEQTGQMSKCDMCVDLLAKGEPPVCVATCP 158
Cdd:cd10556 169 IDQERCRGYRECVEACPYKKPMYNPTTRVSEKCIGCYPRIEEGDQTQCVSACI 221
DMSOR_beta_like cd16367
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 19-163 1.62e-18

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319889 [Multi-domain]  Cd Length: 138  Bit Score: 78.12  E-value: 1.62e-18
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073  19 IDSSRCSGCKACQVACKDKNNlEVGRRFRRVYEVkGGSFIPTgqggvsnnvfaytlsiSCNHCADPVCTKNCPTTAMHkR 98
Cdd:cd16367  16 IDLDRCIRCDNCEKACADTHD-GHSRLDRNGLRF-GNLLVPT----------------ACRHCVDPVCMIGCPTGAIH-R 76

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 16421073  99 PGDGIVRVDtDKCVGCGYCAWSCPYGAPQLNEQTgqmsKCDMCVDLLAkgepPVCVATCPLEAIK 163
Cdd:cd16367  77 DDGGEVVIS-DACCGCGNCASACPYGAIQMVRAV----KCDLCAGYAG----PACVSACPTGAAI 132
PRK12769 PRK12769
putative oxidoreductase Fe-S binding subunit; Reviewed
 20-162 4.44e-18

putative oxidoreductase Fe-S binding subunit; Reviewed


Pssm-ID: 183733 [Multi-domain]  Cd Length: 654  Bit Score: 81.72  E-value: 4.44e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073   20 DSSRCSGCKACQVAC----KDKNNLEVGRRFR-RVYEVKggsfiptgQGGVSNNVFaytlsisCNHCADPVCTKNCPTTA 94
Cdd:PRK12769   8 NSQQCLGCHACEIACvmahNDEQHVLSQHHFHpRITVIK--------HQQQRSAVT-------CHHCEDAPCARSCPNGA 72

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 16421073   95 MhKRPGDGiVRVDTDKCVGCGYCAWSCPYGAPQLNEQTGQMS-------KCDMCVDllaKGEPPVCVATCPLEAI 162
Cdd:PRK12769  73 I-SHVDDS-IQVNQQKCIGCKSCVVACPFGTMQIVLTPVAAGkvkatahKCDLCAG---RENGPACVENCPADAL 142
PRK12809 PRK12809
putative oxidoreductase Fe-S binding subunit; Reviewed
 20-208 8.08e-17

putative oxidoreductase Fe-S binding subunit; Reviewed


Pssm-ID: 183762 [Multi-domain]  Cd Length: 639  Bit Score: 78.14  E-value: 8.08e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073   20 DSSRCSGCKACQVACKDKNNLEVgrrfrrvYEVKGGSFIP----TGQGGVSNnvfaytlSISCNHCADPVCTKNCPTTAM 95
Cdd:PRK12809   8 EAAECIGCHACEIACAVAHNQEN-------WPLSHSDFRPrihvVGKGQAAN-------PVACHHCNNAPCVTACPVNAL 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073   96 HKRPGDgiVRVDTDKCVGCGYCAWSCPYGAPQLNEQTGQmsKCDMCvDLLAKGEpPVCVATCPLEAIKF---GPIDELR- 171
Cdd:PRK12809  74 TFQSDS--VQLDEQKCIGCKRCAIACPFGVVEMVDTIAQ--KCDLC-NQRSSGT-QACIEVCPTQALRLmddKGLQQIKv 147

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 16421073  172 ------AKYGSVCDVNGLPDSSITKPNLVVKAHQGAEKEGKRH 208
Cdd:PRK12809 148 arqrktAAGKASSDAQPSRSAALLPVNSRKGADKISASERKTH 190
DMSOR_beta_like cd16370
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 19-164 1.40e-12

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319892 [Multi-domain]  Cd Length: 131  Bit Score: 62.29  E-value: 1.40e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073  19 IDSSRCSGCKACQVACkdknnlevGRRFRRVYEVKGGSFIPTGQGGVSNNVFAytlsISCNHCADPVCTKNCPTTAMHKR 98
Cdd:cd16370   6 KDMERCIGCYSCMLAC--------SRRVHKSASLSKSAIRVRTRGGLEGGFTV----VVCRACEDPPCAEACPTGALEPR 73

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 16421073  99 PGDGiVRVDTDKCVGCGYCAWSCPYGAPQLNEQTGQMSKCDMCvdllakgepPVCVATCPLEAIKF 164
Cdd:cd16370  74 KGGG-VVLDKEKCIGCGNCVKACIVGAIFWDEETNKPIICIHC---------GYCARYCPHDVLAM 129
PRK10330 PRK10330
electron transport protein HydN;
20-162 8.13e-12

electron transport protein HydN;


Pssm-ID: 182382 [Multi-domain]  Cd Length: 181  Bit Score: 61.44  E-value: 8.13e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073   20 DSSRCSGCKACQVAC-------KDKNNLEVGRRFRRVYEVKGGsfiptgqggvsnNVFAYTLsisCNHCADPVCTKNCPT 92
Cdd:PRK10330   8 DASKCIGCRTCEVACvvshqenQDCASLTPETFLPRIHVIKGV------------NVSTATV---CRQCEDAPCANVCPN 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073   93 TAMHKRpgDGIVRVDTDKCVGCGYCAWSCPYGAPQL-------NEQTG--------QMSKCDMCVdllAKGEPPVCVATC 157
Cdd:PRK10330  73 GAISRD--KGFVHVMQERCIGCKTCVVACPYGAMEVvvrpvirNSGAGlnvraekaEANKCDLCN---HREDGPACMAAC 147


                 ....*
gi 16421073  158 PLEAI 162
Cdd:PRK10330 148 PTHAL 152
HdrA COG1148
Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];
101-164 1.17e-08

Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];


Pssm-ID: 440762 [Multi-domain]  Cd Length: 563  Bit Score: 54.10  E-value: 1.17e-08
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 16421073 101 DGIV-RVDTDKCVGCGYCAWSCPYGAPQLNEQTGQM---SKCDMCvdllakGeppVCVATCPLEAIKF 164
Cdd:COG1148 487 EPSVaEVDPEKCTGCGRCVEVCPYGAISIDEKGVAEvnpALCKGC------G---TCAAACPSGAISL 545
methan_mark_16 TIGR03287
putative methanogenesis marker 16 metalloprotein; Members of this protein family, to date, are ...
 78-129 1.37e-08

putative methanogenesis marker 16 metalloprotein; Members of this protein family, to date, are found in a completed prokaryotic genome if and only if the species is one of the archaeal methanogens. The exact function is unknown, but likely is linked to methanogenesis or a process closely connected to it. This protein is a predicted to bind FeS clusters, based on the presence of two copies of the Fer4 domain (pfam00037), with each copy having four Cys residues invariant across all members. [Energy metabolism, Methanogenesis]


Pssm-ID: 274501 [Multi-domain]  Cd Length: 391  Bit Score: 53.62  E-value: 1.37e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 16421073    78 CNHCADPVCTKNCPTTAMHKrpgDGIVrvDTDKCVGCGYCAWSCPYGAPQLN 129
Cdd:TIGR03287 304 CENCDPCLVEEACPVPAIKK---DGTL--NTEDCFGCGYCAEICPGGAFEVN 350
DMSOR_beta_like cd16372
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 19-163 1.56e-08

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319894 [Multi-domain]  Cd Length: 125  Bit Score: 51.18  E-value: 1.56e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073  19 IDSSRCSGCKACQVACKDKNNLEVGRRFR--RVYEVKGGSFIPTgqggvsnnvfaytlsisCNHCAdpVCTKNCPTTAMH 96
Cdd:cd16372   5 TDPEKCIGCLQCEEACSKTFFKEEDREKSciRITETEGGYAINV-----------------CNQCG--ECIDVCPTGAIT 65

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 16421073  97 KRPGdGIVRVDTDKCVGCGYCAWSCPYGAPQLNEQTGQMSKCDMCvdllakgepPVCVATCPLEAIK 163
Cdd:cd16372  66 RDAN-GVVMINKKLCVGCLMCVGFCPEGAMFKHEDYPEPFKCIAC---------GICVKACPTGALE 122
Nar1 COG4624
Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];
19-152 2.16e-07

Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];


Pssm-ID: 443663 [Multi-domain]  Cd Length: 450  Bit Score: 50.41  E-value: 2.16e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073  19 IDSSRCSGCKACQVACkdknnlevgRRFRRVYEVKGGSFIPTGQGGVSNNVFAYTLSISCNHCAdpvctKNCPTTAMhkR 98
Cdd:COG4624  46 SACSCCPRCCLCCCCC---------CRCCVAISCIQVRGIIIIDKRGPSIIRDKEKCKNCYPCV-----RACPVKAI--K 109

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....
gi 16421073  99 PGDGIVRVDTDKCVGCGYCAWSCPYGAPQLNEQTgqmskcDMCVDLLAKGEPPV 152
Cdd:COG4624 110 VDDGKAEIDEEKCISCGQCVAVCPFGAITEKSDI------EKVKKALKDPEKVV 157
flavo_MJ0208 TIGR02700
archaeoflavoprotein, MJ0208 family; This model describes one of two paralogous families of ...
 78-125 2.43e-07

archaeoflavoprotein, MJ0208 family; This model describes one of two paralogous families of archaealflavoprotein. The other, described by TIGR02699 and typified by the partially characterized AF1518 of Archaeoglobus fulgidus, is a homodimeric FMN-containing flavoprotein that accepts electrons from ferredoxin and can transfer them to various oxidoreductases. The function of this protein family is unknown. [Unknown function, General]


Pssm-ID: 131747 [Multi-domain]  Cd Length: 234  Bit Score: 49.49  E-value: 2.43e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 16421073    78 CNHCAdpVCTKNCPTTAMHKRpgDGIVRVDTDKCVGCGYCAWSCPYGA 125
Cdd:TIGR02700 150 CKGCG--ICVDACPRSAIDMV--DGKAFIRLLKCVGCGKCKEACPYNA 193
COG2768 COG2768
Uncharacterized Fe-S cluster protein [Function unknown];
78-130 2.52e-07

Uncharacterized Fe-S cluster protein [Function unknown];


Pssm-ID: 442050 [Multi-domain]  Cd Length: 74  Bit Score: 46.65  E-value: 2.52e-07
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|...
gi 16421073  78 CNHCAdpVCTKNCPTTAMHkrPGDGIVRVDTDKCVGCGYCAWSCPYGAPQLNE 130
Cdd:COG2768  13 CIGCG--ACVKVCPVGAIS--IEDGKAVIDPEKCIGCGACIEVCPVGAIKIEW 61
DsrA COG2221
Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion ...
 78-125 3.15e-07

Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion transport and metabolism];


Pssm-ID: 441823 [Multi-domain]  Cd Length: 69  Bit Score: 46.20  E-value: 3.15e-07
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*...
gi 16421073  78 CNHCadPVCTKNCPTTAMhkRPGDGIVRVDTDKCVGCGYCAWSCPYGA 125
Cdd:COG2221  17 CIGC--GLCVAVCPTGAI--SLDDGKLVIDEEKCIGCGACIRVCPTGA 60
MtMvhB_like cd10549
Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...
 78-163 3.34e-07

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.


Pssm-ID: 319871 [Multi-domain]  Cd Length: 128  Bit Score: 47.39  E-value: 3.34e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073  78 CNHCADpvCTKNCPTTAMHKRPGDGIVR---VDTDKCVGCGYCAWSCPYGAPQLNEQTGQMSKCDMcvDLLAKGEPPV-- 152
Cdd:cd10549   8 CIGCGI--CVKACPTDAIELGPNGAIARgpeIDEDKCVFCGACVEVCPTGAIELTPEGKEYVPKEK--EAEIDEEKCIgc 83

                        90
                ....*....|...
gi 16421073 153 --CVATCPLEAIK 163
Cdd:cd10549  84 glCVKVCPVDAIT 96
NapF COG1145
Ferredoxin [Energy production and conversion];
78-125 4.96e-07

Ferredoxin [Energy production and conversion];


Pssm-ID: 440760 [Multi-domain]  Cd Length: 238  Bit Score: 48.95  E-value: 4.96e-07
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*...
gi 16421073  78 CNHCAdpVCTKNCPTTAMHKRPGDGIVRVDTDKCVGCGYCAWSCPYGA 125
Cdd:COG1145 184 CIGCG--LCVKVCPTGAIRLKDGKPQIVVDPDKCIGCGACVKVCPVGA 229
COG1149 COG1149
MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function ...
 103-166 5.54e-07

MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function prediction only];


Pssm-ID: 440763 [Multi-domain]  Cd Length: 68  Bit Score: 45.49  E-value: 5.54e-07
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 16421073 103 IVRVDTDKCVGCGYCAWSCPYGAPQLNEQTGQM---SKCDMCVdllakgeppVCVATCPLEAIKFGP 166
Cdd:COG1149   5 IPVIDEEKCIGCGLCVEVCPEGAIKLDDGGAPVvdpDLCTGCG---------ACVGVCPTGAITLEE 62
PRK12771 PRK12771
putative glutamate synthase (NADPH) small subunit; Provisional
 77-128 5.86e-07

putative glutamate synthase (NADPH) small subunit; Provisional


Pssm-ID: 237198 [Multi-domain]  Cd Length: 564  Bit Score: 49.10  E-value: 5.86e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 16421073   77 SCNHCAD-PVCTKNCPTTAMHKRPGDGIVRVDTDKCVGCGYCAWSCPYGAPQL 128
Cdd:PRK12771 508 SCGNCFEcDNCYGACPQDAIIKLGPGRRYHFDYDKCTGCHICADVCPCGAIEM 560
PreA COG1146
NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and ...
 102-171 4.47e-06

NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and metabolism];


Pssm-ID: 440761 [Multi-domain]  Cd Length: 67  Bit Score: 42.77  E-value: 4.47e-06
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 16421073 102 GIVRVDTDKCVGCGYCAWSCPYGAPQLNEQTGQM--SKCDMCVDLLAkgeppvCVATCPLEAIKFGPIDELR 171
Cdd:COG1146   1 MMPVIDTDKCIGCGACVEVCPVDVLELDEEGKKAlvINPEECIGCGA------CELVCPVGAITVEDDEPEE 66
vorD PRK09623
3-methyl-2-oxobutanoate dehydrogenase subunit delta;
85-125 7.46e-06

3-methyl-2-oxobutanoate dehydrogenase subunit delta;


Pssm-ID: 170016 [Multi-domain]  Cd Length: 105  Bit Score: 43.40  E-value: 7.46e-06
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 16421073   85 VCTKNCPTTAMHKRPgDGIVRVDTDKCVGCGYCAWSCPYGA 125
Cdd:PRK09623  58 ICWKFCPEPAIYIKE-DGYVAIDYDYCKGCGICANECPTKA 97
NapF COG1145
Ferredoxin [Energy production and conversion];
103-168 9.27e-06

Ferredoxin [Energy production and conversion];


Pssm-ID: 440760 [Multi-domain]  Cd Length: 238  Bit Score: 45.10  E-value: 9.27e-06
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073 103 IVRVDTDKCVGCGYCAWSCPYGAPQLNEQTGQM----SKCDMCvdllakgepPVCVATCPLEAIKFGPID 168
Cdd:COG1145 176 KAVIDAEKCIGCGLCVKVCPTGAIRLKDGKPQIvvdpDKCIGC---------GACVKVCPVGAISLEPKE 236
COG2768 COG2768
Uncharacterized Fe-S cluster protein [Function unknown];
101-166 1.49e-05

Uncharacterized Fe-S cluster protein [Function unknown];


Pssm-ID: 442050 [Multi-domain]  Cd Length: 74  Bit Score: 41.64  E-value: 1.49e-05
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 16421073 101 DGIVRVDTDKCVGCGYCAWSCPYGAPQLNEQTGQM--SKCDMCvdllakgepPVCVATCPLEAIKFGP 166
Cdd:COG2768   3 LGKPYVDEEKCIGCGACVKVCPVGAISIEDGKAVIdpEKCIGC---------GACIEVCPVGAIKIEW 61
IorA COG4231
TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and ...
 92-163 2.28e-05

TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and conversion];


Pssm-ID: 443375 [Multi-domain]  Cd Length: 76  Bit Score: 41.18  E-value: 2.28e-05
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 16421073  92 TTAMHkrpgdgiVRVDTDKCVGCGYCAWSCPYGAPQLNEQTGQ--MSKCDMCVdllakgeppVCVATCPLEAIK 163
Cdd:COG4231  12 TTAMR-------YVIDEDKCTGCGACVKVCPADAIEEGDGKAVidPDLCIGCG---------SCVQVCPVDAIK 69
IorA COG4231
TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and ...
 78-125 2.70e-05

TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and conversion];


Pssm-ID: 443375 [Multi-domain]  Cd Length: 76  Bit Score: 41.18  E-value: 2.70e-05
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*...
gi 16421073  78 CNHCADpvCTKNCPTTAMHKrpGDGIVRVDTDKCVGCGYCAWSCPYGA 125
Cdd:COG4231  24 CTGCGA--CVKVCPADAIEE--GDGKAVIDPDLCIGCGSCVQVCPVDA 67
NapH COG0348
Polyferredoxin NapH [Energy production and conversion];
103-165 2.84e-05

Polyferredoxin NapH [Energy production and conversion];


Pssm-ID: 440117 [Multi-domain]  Cd Length: 263  Bit Score: 43.51  E-value: 2.84e-05
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 16421073 103 IVRVDTDKCVGCGYCAWSCPYGAPQLNEQTGQMSkCDMCVDllakgeppvCVATCPLEAIKFG 165
Cdd:COG0348 204 RVRYDRGDCIDCGLCVKVCPMGIDIRKGEINQSE-CINCGR---------CIDACPKDAIRFS 256
MtMvhB_like cd10549
Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...
 19-125 3.22e-05

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.


Pssm-ID: 319871 [Multi-domain]  Cd Length: 128  Bit Score: 42.00  E-value: 3.22e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073  19 IDSSRCSGCKACQVACKdKNNLEVGRRFRRVYEVKGGSFIPtgqggvsnnvfaytlSISCNHCAdpVCTKNCPTTAMhKR 98
Cdd:cd10549  37 IDEDKCVFCGACVEVCP-TGAIELTPEGKEYVPKEKEAEID---------------EEKCIGCG--LCVKVCPVDAI-TL 97

                        90       100
                ....*....|....*....|....*..
gi 16421073  99 PGDGIVRVDTDKCVGCGYCAWSCPYGA 125
Cdd:cd10549  98 EDELEIVIDKEKCIGCGICAEVCPVNA 124
DMSOR_beta_like cd16373
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 71-122 4.03e-05

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319895 [Multi-domain]  Cd Length: 154  Bit Score: 42.24  E-value: 4.03e-05
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....
gi 16421073  71 AYTLSISCNhcadpVCTKNCPT--TAMHKRPGDGIVRVDTDKCVGCGYCAWSCP 122
Cdd:cd16373  95 AWQGGTDCG-----VCVEACPTeaIAIVLEDDVLRPVVDEDKCVGCGLCEYVCP 143
PorD COG1144
Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta ...
 78-125 4.96e-05

Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit [Energy production and conversion]; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit is part of the Pathway/BioSystem: Pyruvate oxidation


Pssm-ID: 440759 [Multi-domain]  Cd Length: 84  Bit Score: 40.42  E-value: 4.96e-05
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*...
gi 16421073  78 CNHCAdpVCTKNCPTTAMHKRPGdGIVRVDTDKCVGCGYCAWSCPYGA 125
Cdd:COG1144  32 CIGCG--LCWIVCPDGAIRVDDG-KYYGIDYDYCKGCGICAEVCPVKA 76
PRK13795 PRK13795
hypothetical protein; Provisional
 85-122 6.04e-05

hypothetical protein; Provisional


Pssm-ID: 237510 [Multi-domain]  Cd Length: 636  Bit Score: 43.06  E-value: 6.04e-05
                         10        20        30
                 ....*....|....*....|....*....|....*...
gi 16421073   85 VCTKNCPTTAMHKRPGDGIVRVDTDKCVGCGYCAWSCP 122
Cdd:PRK13795 588 VCVGACPTGAIRIEEGKRKISVDEEKCIHCGKCTEVCP 625
COG1149 COG1149
MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function ...
 78-125 6.05e-05

MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function prediction only];


Pssm-ID: 440763 [Multi-domain]  Cd Length: 68  Bit Score: 39.71  E-value: 6.05e-05
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*...
gi 16421073  78 CNHCAdpVCTKNCPTTAMHKRPGDGIVrVDTDKCVGCGYCAWSCPYGA 125
Cdd:COG1149  13 CIGCG--LCVEVCPEGAIKLDDGGAPV-VDPDLCTGCGACVGVCPTGA 57
PRK07118 PRK07118
Fe-S cluster domain-containing protein;
19-125 8.53e-05

Fe-S cluster domain-containing protein;


Pssm-ID: 235941 [Multi-domain]  Cd Length: 280  Bit Score: 42.23  E-value: 8.53e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073   19 IDSSRCSGCKACQVACKdKNNLEVGRRFRRVYeVKGGSfipTGQGGVSNNVfaytLSISCNHCAdpVCTKNCPTTAMHKR 98
Cdd:PRK07118 165 VDEDKCTGCGACVKACP-RNVIELIPKSARVF-VACNS---KDKGKAVKKV----CEVGCIGCG--KCVKACPAGAITME 233

                         90       100
                 ....*....|....*....|....*..
gi 16421073   99 pgDGIVRVDTDKCVGCGYCAWSCPYGA 125
Cdd:PRK07118 234 --NNLAVIDQEKCTSCGKCVEKCPTKA 258
HdrA COG1148
Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];
78-135 9.84e-05

Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];


Pssm-ID: 440762 [Multi-domain]  Cd Length: 563  Bit Score: 42.54  E-value: 9.84e-05
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 16421073  78 CNHCAdpVCTKNCPTTAMHKRPgDGIVRVDTDKCVGCGYCAWSCPYGAPQLNEQTGQM 135
Cdd:COG1148 498 CTGCG--RCVEVCPYGAISIDE-KGVAEVNPALCKGCGTCAAACPSGAISLKGFTDDQ 552
PRK07118 PRK07118
Fe-S cluster domain-containing protein;
86-124 9.90e-05

Fe-S cluster domain-containing protein;


Pssm-ID: 235941 [Multi-domain]  Cd Length: 280  Bit Score: 42.23  E-value: 9.90e-05
                         10        20        30
                 ....*....|....*....|....*....|....*....
gi 16421073   86 CTKNCPTTAMHKrpGDGIVRVDTDKCVGCGYCAWSCPYG 124
Cdd:PRK07118 147 CVAACPFDAIHI--ENGLPVVDEDKCTGCGACVKACPRN 183
MtMvhB_like cd10549
Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...
 106-173 1.01e-04

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.


Pssm-ID: 319871 [Multi-domain]  Cd Length: 128  Bit Score: 40.46  E-value: 1.01e-04
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 16421073 106 VDTDKCVGCGYCAWSCPYGAPQLNEQTGQ-------MSKCDMCvdllakgepPVCVATCPLEAIKFGPIDELRAK 173
Cdd:cd10549   3 YDPEKCIGCGICVKACPTDAIELGPNGAIargpeidEDKCVFC---------GACVEVCPTGAIELTPEGKEYVP 68
RnfB COG2878
Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit [Energy production and ...
 86-122 1.63e-04

Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit [Energy production and conversion]; Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit is part of the Pathway/BioSystem: Na+-translocating Fd:NADH oxidoreductase


Pssm-ID: 442125 [Multi-domain]  Cd Length: 254  Bit Score: 41.13  E-value: 1.63e-04
                        10        20        30
                ....*....|....*....|....*....|....*..
gi 16421073  86 CTKNCPTTAMHKRPgDGIVRVDTDKCVGCGYCAWSCP 122
Cdd:COG2878 145 CIKACPFDAIVGAA-KGMHTVDEDKCTGCGLCVEACP 180
NuoI COG1143
Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy ...
 76-125 2.02e-04

Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy production and conversion]; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440758 [Multi-domain]  Cd Length: 66  Bit Score: 38.19  E-value: 2.02e-04
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|
gi 16421073  76 ISCNHCADpVCTKNCPTtaMHKRPGDGIVRVDTDKCVGCGYCAWSCPYGA 125
Cdd:COG1143   5 IGCGLCVR-VCPVDAIT--IEDGEPGKVYVIDPDKCIGCGLCVEVCPTGA 51
NuoI COG1143
Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy ...
 108-168 3.07e-04

Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy production and conversion]; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440758 [Multi-domain]  Cd Length: 66  Bit Score: 37.80  E-value: 3.07e-04
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 16421073 108 TDKCVGCGYCAWSCPYGAPQLNEQTGQ------MSKCDMCVdllakgeppVCVATCPLEAIKFGPID 168
Cdd:COG1143   1 EDKCIGCGLCVRVCPVDAITIEDGEPGkvyvidPDKCIGCG---------LCVEVCPTGAISMTPFE 58
PRK05888 PRK05888
NADH-quinone oxidoreductase subunit NuoI;
110-170 3.94e-04

NADH-quinone oxidoreductase subunit NuoI;


Pssm-ID: 235637 [Multi-domain]  Cd Length: 164  Bit Score: 39.48  E-value: 3.94e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 16421073  110 KCVGCGYCAWSCPYGAPQLneQTGQ--------------MSKCDMCvDLlakgeppvCVATCPLEAIKFGPIDEL 170
Cdd:PRK05888  59 RCIACKLCAAICPADAITI--EAAEredgrrrttrydinFGRCIFC-GF--------CEEACPTDAIVETPDFEL 122
ferrodoxin_EFR1 NF038196
EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight ...
 108-165 5.94e-04

EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight conserved Cys residues in two CxxCxxCxxxCP motifs, each of which binds a 4Fe-4S cluster. The N-terminal region resembles flavodoxin domains, with some members of the family recognized by Pfam models PF12724 (Flavodoxin_5) or PF00258 (Flavodoxin_1).


Pssm-ID: 468407 [Multi-domain]  Cd Length: 243  Bit Score: 39.46  E-value: 5.94e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 16421073  108 TDKCVGCGYCAWSCPYGAPQLNEqtGQ---MSKCDMCvdlLAkgeppvCVATCPLEAIKFG 165
Cdd:NF038196 184 TDKCIGCGICAKVCPVNNIEMED--GKpvwGHNCTHC---LA------CIHRCPKEAIEYG 233
NapF_like cd10564
NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, ...
 76-131 6.33e-04

NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, the iron-sulfur subunit of periplasmic nitrate reductase. The periplasmic nitrate reductase NapABC of Escherichia coli likely functions during anaerobic growth in low-nitrate environments; napF operon expression is activated by cyclic AMP receptor protein (Crp). NapF is a subfamily of the beta subunit of DMSO reductase (DMSOR) family. DMSOR family members have a large, periplasmic molybdenum-containing alpha subunit as well as a small beta FeS subunit, and may also have a small gamma subunit. The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319886 [Multi-domain]  Cd Length: 139  Bit Score: 38.38  E-value: 6.33e-04
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 16421073  76 ISCNHCADpvctkNCPTTAMHKRPGDGIV---RVDTDKCVGCGYCAWSCPYGAPQLNEQ 131
Cdd:cd10564  86 VECRSCQD-----ACPTQAIRFRPRLGGIalpELDADACTGCGACVSVCPVGAITLTPL 139
PRK13795 PRK13795
hypothetical protein; Provisional
 110-164 7.90e-04

hypothetical protein; Provisional


Pssm-ID: 237510 [Multi-domain]  Cd Length: 636  Bit Score: 39.59  E-value: 7.90e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 16421073  110 KCVGCGYCAWSCPYGAPQLNEQTGQMS----KCDMCvdllakGEppvCVATCPLEAIKF 164
Cdd:PRK13795 582 ECVGCGVCVGACPTGAIRIEEGKRKISvdeeKCIHC------GK---CTEVCPVVKYKD 631
Fer4_6 pfam12837
4Fe-4S binding domain; This superfamily includes proteins containing domains which bind to ...
 103-126 8.42e-04

4Fe-4S binding domain; This superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich.


Pssm-ID: 432822 [Multi-domain]  Cd Length: 24  Bit Score: 35.67  E-value: 8.42e-04
                          10        20
                  ....*....|....*....|....
gi 16421073   103 IVRVDTDKCVGCGYCAWSCPYGAP 126
Cdd:pfam12837   1 VVEVDPDKCIGCGRCVVVCPYGAI 24
Nar1 COG4624
Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];
23-163 8.74e-04

Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];


Pssm-ID: 443663 [Multi-domain]  Cd Length: 450  Bit Score: 39.62  E-value: 8.74e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073  23 RCSGCKACQVACKDKNNLEVGRRFRRVYEVKGGSfiptgqggVSNNVFAYTLSISCNHCADPVCTKNCPTTAMH------ 96
Cdd:COG4624   4 LLRACCCCCIEEGDELLLLEEAERVLRIIILEAL--------LPEHVDDDSACSCCPRCCLCCCCCCRCCVAISciqvrg 75

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 16421073  97 ---KRPGDGIVRVDTDKCVGCGYCAWSCPYGAPQLNEQTGQM--SKCDMCvdllakGEppvCVATCPLEAIK 163
Cdd:COG4624  76 iiiIDKRGPSIIRDKEKCKNCYPCVRACPVKAIKVDDGKAEIdeEKCISC------GQ---CVAVCPFGAIT 138
Fer4 pfam00037
4Fe-4S binding domain; Superfamily includes proteins containing domains which bind to ...
 104-125 1.16e-03

4Fe-4S binding domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich.


Pssm-ID: 459642 [Multi-domain]  Cd Length: 24  Bit Score: 35.30  E-value: 1.16e-03
                          10        20
                  ....*....|....*....|..
gi 16421073   104 VRVDTDKCVGCGYCAWSCPYGA 125
Cdd:pfam00037   1 VVIDEEKCIGCGACVEVCPVGA 22
Fer4_10 pfam13237
4Fe-4S dicluster domain; This family includes proteins containing domains which bind to ...
 78-122 1.79e-03

4Fe-4S dicluster domain; This family includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. The structure of the domain is an alpha-antiparallel beta sandwich.


Pssm-ID: 404174 [Multi-domain]  Cd Length: 56  Bit Score: 35.30  E-value: 1.79e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 16421073    78 CNHCADpvCTKNCPTTAMH-----KRPGDGIVRVDTDKCVGCGYCAWSCP 122
Cdd:pfam13237   9 CIGCGR--CTAACPAGLTRvgaivERLEGEAVRIGVWKCIGCGACVEACP 56
Fer COG1141
Ferredoxin [Energy production and conversion];
104-122 2.72e-03

Ferredoxin [Energy production and conversion];


Pssm-ID: 440756 [Multi-domain]  Cd Length: 63  Bit Score: 35.24  E-value: 2.72e-03
                        10
                ....*....|....*....
gi 16421073 104 VRVDTDKCVGCGYCAWSCP 122
Cdd:COG1141   3 VTVDRDTCIGCGLCVALAP 21
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
 78-125 3.06e-03

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 37.84  E-value: 3.06e-03
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|...
gi 16421073  78 CNHcadpVCTKNCP-----TTAMHKRPGDGIVRVDTDKCVGCGYCAWSCPYGA 125
Cdd:COG1245  17 CNY----ECIKYCPvnrtgKEAIEIDEDDGKPVISEELCIGCGICVKKCPFDA 65
DsrA COG2221
Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion ...
 103-163 3.56e-03

Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion transport and metabolism];


Pssm-ID: 441823 [Multi-domain]  Cd Length: 69  Bit Score: 35.03  E-value: 3.56e-03
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 16421073 103 IVRVDTDKCVGCGYCAWSCPYGAPQLNEQTGQ--MSKCDMCvdllakGEppvCVATCPLEAIK 163
Cdd:COG2221   9 PPKIDEEKCIGCGLCVAVCPTGAISLDDGKLVidEEKCIGC------GA---CIRVCPTGAIK 62
Fer4_7 pfam12838
4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to ...
 78-125 3.96e-03

4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contains two 4Fe4S clusters.


Pssm-ID: 463724 [Multi-domain]  Cd Length: 51  Bit Score: 34.42  E-value: 3.96e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 16421073    78 CNHCADpvCTKNCPTTAM-----HKRPGDGIVRVDTDKCVGCGYCAWSCPYGA 125
Cdd:pfam12838   1 CIGCGA--CVAACPVGAItldevGEKKGTKTVVIDPERCVGCGACVAVCPTGA 51
DMSOR_beta_like cd16373
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 78-125 4.19e-03

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319895 [Multi-domain]  Cd Length: 154  Bit Score: 36.46  E-value: 4.19e-03
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073  78 CNHCADpVCTKNCPTTAMHKRPGD------GIVRVDTDKCV------GCGYCAWSCPYGA 125
Cdd:cd16373  55 CDLCCD-ACVEVCPTGALRPLDLEeqkvkmGVAVIDKDRCLawqggtDCGVCVEACPTEA 113
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
78-125 4.46e-03

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 37.48  E-value: 4.46e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 16421073   78 CNHcadpVCTKNCPTTAMHKR-----PGDGIVRVDTDKCVGCGYCAWSCPYGA 125
Cdd:PRK13409  17 CNY----ECIKYCPVVRTGEEtieidEDDGKPVISEELCIGCGICVKKCPFDA 65
PRK10194 PRK10194
ferredoxin-type protein NapF;
7-125 5.14e-03

ferredoxin-type protein NapF;


Pssm-ID: 182296 [Multi-domain]  Cd Length: 163  Bit Score: 36.15  E-value: 5.14e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16421073    7 YPPVSDKQlgffidsSRCSGCKACQVACKDKNNLEvgrRFRRVYEVkggsfiptgQGGVSNNVFAYTlSISCNHCADpvc 86
Cdd:PRK10194  58 YPSVNFKN-------NECSFCYACAQACPESLFSP---RHTRAWDL---------QFTIGDACLAYQ-SVECRRCQD--- 114

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 16421073   87 tkNCPTTAMHKRPG-DGIVR--VDTDKCVGCGYCAWSCPYGA 125
Cdd:PRK10194 115 --SCEPMAIIFRPTlSGIYQpqLNSQLCNGCGACAASCPVSA 154
PRK08348 PRK08348
NADH-plastoquinone oxidoreductase subunit; Provisional
 102-148 6.08e-03

NADH-plastoquinone oxidoreductase subunit; Provisional


Pssm-ID: 181399 [Multi-domain]  Cd Length: 120  Bit Score: 35.58  E-value: 6.08e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 16421073  102 GIVRVDTDKCVGCGYCAWSCPYGA-PQLNEQ------TGQMSKCDMCVDLLAKG 148
Cdd:PRK08348  35 GKILYDVDKCVGCRMCVTVCPAGVfVYLPEIrkvalwTGRCVFCGQCVDVCPTG 88
PorD COG1144
Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta ...
 106-169 6.86e-03

Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit [Energy production and conversion]; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit is part of the Pathway/BioSystem: Pyruvate oxidation


Pssm-ID: 440759 [Multi-domain]  Cd Length: 84  Bit Score: 34.64  E-value: 6.86e-03
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 16421073 106 VDTDKCVGCGYCAWSCPYGAPQLNEQTGQMSKCDMCVDLLakgeppVCVATCPLEAIKFGPIDE 169
Cdd:COG1144  27 VDEDKCIGCGLCWIVCPDGAIRVDDGKYYGIDYDYCKGCG------ICAEVCPVKAIEMVPEEK 84
PRK13984 PRK13984
putative oxidoreductase; Provisional
 107-148 9.53e-03

putative oxidoreductase; Provisional


Pssm-ID: 172486 [Multi-domain]  Cd Length: 604  Bit Score: 36.28  E-value: 9.53e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 16421073  107 DTDKCVGCGYCAWSCPYGA------PQLNEQTGQM-----------SKCDMCVDLLAKG 148
Cdd:PRK13984  43 DWEKCIGCGTCSKICPTDAitmvevPDLPQEYGKKpqrpvidygrcSFCALCVDICTTG 101
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH