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Conserved domains on  [gi|18027408|gb|AAL55786|]
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unknown [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LOR super family cl02043
LURP-one-related; The structure of this family has been solved. It comprises a 12-stranded ...
 62-100 2.36e-10

LURP-one-related; The structure of this family has been solved. It comprises a 12-stranded beta barrel with a central C-terminal alpha helix. This helix is thought to be a transmembrane helix. It is structurally similar to the C-terminal domain of the Tubby protein. In plants it plays a role in defense against pathogens.


The actual alignment was detected with superfamily member pfam03803:

Pssm-ID: 470445  Cd Length: 221  Bit Score: 58.14  E-value: 2.36e-10
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 18027408    62 SAAPFLPLPGVPSGLEFLVQIDQILIHQKAERVETFLGW 100
Cdd:pfam03803   1 MSGPGQPPANCPAGLEYLLQLDQILVHQQIEPLEVFTGF 39
PRK05641 super family cl35354
putative acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated
 31-71 4.06e-03

putative acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated


The actual alignment was detected with superfamily member PRK05641:

Pssm-ID: 235540 [Multi-domain]  Cd Length: 153  Bit Score: 36.76  E-value: 4.06e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 18027408   31 PGPGQAPVPAQVPAPAPGFALFPSPGPVALGSAAPFLPLPG 71
Cdd:PRK05641  53 PTPAPAPAPAVPSAPTPVAPAAPAPAPASAGENVVTAPMPG 93
 
Name Accession Description Interval E-value
Scramblase pfam03803
Scramblase; Scramblase is palmitoylated and contains a potential protein kinase C ...
 62-100 2.36e-10

Scramblase; Scramblase is palmitoylated and contains a potential protein kinase C phosphorylation site. Scramblase exhibits Ca2+-activated phospholipid scrambling activity in vitro. There are also possible SH3 and WW binding motifs. Scramblase is involved in the redistribution of phospholipids after cell activation or injury.


Pssm-ID: 252175  Cd Length: 221  Bit Score: 58.14  E-value: 2.36e-10
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 18027408    62 SAAPFLPLPGVPSGLEFLVQIDQILIHQKAERVETFLGW 100
Cdd:pfam03803   1 MSGPGQPPANCPAGLEYLLQLDQILVHQQIEPLEVFTGF 39
PRK05641 PRK05641
putative acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated
 31-71 4.06e-03

putative acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated


Pssm-ID: 235540 [Multi-domain]  Cd Length: 153  Bit Score: 36.76  E-value: 4.06e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 18027408   31 PGPGQAPVPAQVPAPAPGFALFPSPGPVALGSAAPFLPLPG 71
Cdd:PRK05641  53 PTPAPAPAPAVPSAPTPVAPAAPAPAPASAGENVVTAPMPG 93
 
Name Accession Description Interval E-value
Scramblase pfam03803
Scramblase; Scramblase is palmitoylated and contains a potential protein kinase C ...
 62-100 2.36e-10

Scramblase; Scramblase is palmitoylated and contains a potential protein kinase C phosphorylation site. Scramblase exhibits Ca2+-activated phospholipid scrambling activity in vitro. There are also possible SH3 and WW binding motifs. Scramblase is involved in the redistribution of phospholipids after cell activation or injury.


Pssm-ID: 252175  Cd Length: 221  Bit Score: 58.14  E-value: 2.36e-10
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 18027408    62 SAAPFLPLPGVPSGLEFLVQIDQILIHQKAERVETFLGW 100
Cdd:pfam03803   1 MSGPGQPPANCPAGLEYLLQLDQILVHQQIEPLEVFTGF 39
PRK05641 PRK05641
putative acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated
 31-71 4.06e-03

putative acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated


Pssm-ID: 235540 [Multi-domain]  Cd Length: 153  Bit Score: 36.76  E-value: 4.06e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 18027408   31 PGPGQAPVPAQVPAPAPGFALFPSPGPVALGSAAPFLPLPG 71
Cdd:PRK05641  53 PTPAPAPAPAVPSAPTPVAPAAPAPAPASAGENVVTAPMPG 93
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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