response regulator GacA, partial [Pseudomonas putida]
List of domain hits
Name | Accession | Description | Interval | E-value | |||
PRK09483 super family | cl35841 | response regulator; Provisional |
1-134 | 2.08e-69 | |||
response regulator; Provisional The actual alignment was detected with superfamily member PRK09483: Pssm-ID: 236538 [Multi-domain] Cd Length: 217 Bit Score: 207.65 E-value: 2.08e-69
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Name | Accession | Description | Interval | E-value | |||
PRK09483 | PRK09483 | response regulator; Provisional |
1-134 | 2.08e-69 | |||
response regulator; Provisional Pssm-ID: 236538 [Multi-domain] Cd Length: 217 Bit Score: 207.65 E-value: 2.08e-69
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REC_NarL-like | cd17535 | phosphoacceptor receiver (REC) domain of NarL (Nitrate/Nitrite response regulator L) family ... |
1-58 | 2.02e-16 | |||
phosphoacceptor receiver (REC) domain of NarL (Nitrate/Nitrite response regulator L) family response regulators; The NarL family is one of the more abundant families of DNA-binding response regulators (RRs). Members of the NarL family contain a REC domain and a helix-turn-helix (HTH) DNA-binding output domain, with a majority of members containing a LuxR-type HTH domain. They function as transcriptional regulators. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays. Pssm-ID: 381090 [Multi-domain] Cd Length: 117 Bit Score: 69.85 E-value: 2.02e-16
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HTH_LUXR | smart00421 | helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon |
83-134 | 3.40e-14 | |||
helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon Pssm-ID: 197715 [Multi-domain] Cd Length: 58 Bit Score: 62.54 E-value: 3.40e-14
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FixJ | COG4566 | DNA-binding response regulator, FixJ family, consists of REC and HTH domains [Signal ... |
8-132 | 1.40e-11 | |||
DNA-binding response regulator, FixJ family, consists of REC and HTH domains [Signal transduction mechanisms, Transcription]; Pssm-ID: 443623 [Multi-domain] Cd Length: 196 Bit Score: 58.96 E-value: 1.40e-11
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GerE | pfam00196 | Bacterial regulatory proteins, luxR family; |
84-134 | 4.25e-10 | |||
Bacterial regulatory proteins, luxR family; Pssm-ID: 425517 [Multi-domain] Cd Length: 57 Bit Score: 51.82 E-value: 4.25e-10
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Name | Accession | Description | Interval | E-value | |||
PRK09483 | PRK09483 | response regulator; Provisional |
1-134 | 2.08e-69 | |||
response regulator; Provisional Pssm-ID: 236538 [Multi-domain] Cd Length: 217 Bit Score: 207.65 E-value: 2.08e-69
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PRK10360 | PRK10360 | transcriptional regulator UhpA; |
6-134 | 4.55e-19 | |||
transcriptional regulator UhpA; Pssm-ID: 182408 [Multi-domain] Cd Length: 196 Bit Score: 78.48 E-value: 4.55e-19
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REC_NarL-like | cd17535 | phosphoacceptor receiver (REC) domain of NarL (Nitrate/Nitrite response regulator L) family ... |
1-58 | 2.02e-16 | |||
phosphoacceptor receiver (REC) domain of NarL (Nitrate/Nitrite response regulator L) family response regulators; The NarL family is one of the more abundant families of DNA-binding response regulators (RRs). Members of the NarL family contain a REC domain and a helix-turn-helix (HTH) DNA-binding output domain, with a majority of members containing a LuxR-type HTH domain. They function as transcriptional regulators. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays. Pssm-ID: 381090 [Multi-domain] Cd Length: 117 Bit Score: 69.85 E-value: 2.02e-16
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PRK15369 | PRK15369 | two component system response regulator; |
1-128 | 1.44e-15 | |||
two component system response regulator; Pssm-ID: 185267 [Multi-domain] Cd Length: 211 Bit Score: 69.72 E-value: 1.44e-15
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HTH_LUXR | smart00421 | helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon |
83-134 | 3.40e-14 | |||
helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon Pssm-ID: 197715 [Multi-domain] Cd Length: 58 Bit Score: 62.54 E-value: 3.40e-14
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FixJ | COG4566 | DNA-binding response regulator, FixJ family, consists of REC and HTH domains [Signal ... |
8-132 | 1.40e-11 | |||
DNA-binding response regulator, FixJ family, consists of REC and HTH domains [Signal transduction mechanisms, Transcription]; Pssm-ID: 443623 [Multi-domain] Cd Length: 196 Bit Score: 58.96 E-value: 1.40e-11
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PRK10651 | PRK10651 | transcriptional regulator NarL; Provisional |
1-134 | 7.70e-11 | |||
transcriptional regulator NarL; Provisional Pssm-ID: 182619 [Multi-domain] Cd Length: 216 Bit Score: 57.35 E-value: 7.70e-11
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CitB | COG2197 | DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains [Signal ... |
78-134 | 8.33e-11 | |||
DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains [Signal transduction mechanisms, Transcription]; Pssm-ID: 441799 [Multi-domain] Cd Length: 131 Bit Score: 55.67 E-value: 8.33e-11
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GerE | pfam00196 | Bacterial regulatory proteins, luxR family; |
84-134 | 4.25e-10 | |||
Bacterial regulatory proteins, luxR family; Pssm-ID: 425517 [Multi-domain] Cd Length: 57 Bit Score: 51.82 E-value: 4.25e-10
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LuxR_C_like | cd06170 | C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix ... |
86-134 | 1.04e-08 | |||
C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many are active as homodimers. Many are two domain proteins in which the DNA binding property of the C-terminal DNA binding domain is modulated by modifications of the N-terminal domain. For example in the case of Lux R which participates in the regulation of gene expression in response to fluctuations in cell-population density (quorum-sensing), a signaling molecule, the pheromone Acyl HSL (N-acyl derivatives of homoserine lactone), binds to the N-terminal domain and leads to LuxR dimerization. For others phophorylation of the N-terminal domain leads to multimerization, for example Escherichia coli NarL and Sinorhizobium melilot FixJ. NarL controls gene expression of many respiratory-related operons when environmental nitrate or nitrite is present under anerobic conditions. FixJ is involved in the transcriptional activation of nitrogen fixation genes. The group also includes small proteins which lack an N-terminal signaling domain, such as Bacillus subtilis GerE. GerE is dimeric and acts in conjunction with sigmaK as an activator or a repressor modulating the expression of various genes in particular those encoding the spore-coat. These LuxR family regulators may share a similar organization of their target binding sites. For example the LuxR dimer binds the lux box, a 20bp inverted repeat, GerE dimers bind two 12bp consensus sequences in inverted orientation having the central four bases overlap, and the NarL dimer binds two 7bp inverted repeats separated by 2 bp. Pssm-ID: 99777 [Multi-domain] Cd Length: 57 Bit Score: 48.30 E-value: 1.04e-08
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Response_reg | pfam00072 | Response regulator receiver domain; This domain receives the signal from the sensor partner in ... |
1-54 | 2.96e-08 | |||
Response regulator receiver domain; This domain receives the signal from the sensor partner in bacterial two-component systems. It is usually found N-terminal to a DNA binding effector domain. Pssm-ID: 395025 [Multi-domain] Cd Length: 111 Bit Score: 48.30 E-value: 2.96e-08
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CsgD | COG2771 | DNA-binding transcriptional regulator, CsgD family [Transcription]; |
82-132 | 4.57e-08 | |||
DNA-binding transcriptional regulator, CsgD family [Transcription]; Pssm-ID: 442052 [Multi-domain] Cd Length: 188 Bit Score: 49.37 E-value: 4.57e-08
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PRK09958 | PRK09958 | acid-sensing system DNA-binding response regulator EvgA; |
30-132 | 1.36e-07 | |||
acid-sensing system DNA-binding response regulator EvgA; Pssm-ID: 182168 [Multi-domain] Cd Length: 204 Bit Score: 48.35 E-value: 1.36e-07
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PRK09935 | PRK09935 | fimbriae biosynthesis transcriptional regulator FimZ; |
5-134 | 2.52e-07 | |||
fimbriae biosynthesis transcriptional regulator FimZ; Pssm-ID: 182154 [Multi-domain] Cd Length: 210 Bit Score: 47.56 E-value: 2.52e-07
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PRK10403 | PRK10403 | nitrate/nitrite response regulator protein NarP; |
15-134 | 3.69e-07 | |||
nitrate/nitrite response regulator protein NarP; Pssm-ID: 182431 [Multi-domain] Cd Length: 215 Bit Score: 47.15 E-value: 3.69e-07
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CheY | COG0784 | CheY-like REC (receiver) domain, includes chemotaxis protein CheY and sporulation regulator ... |
1-61 | 1.01e-05 | |||
CheY-like REC (receiver) domain, includes chemotaxis protein CheY and sporulation regulator Spo0F [Signal transduction mechanisms]; Pssm-ID: 440547 [Multi-domain] Cd Length: 128 Bit Score: 42.14 E-value: 1.01e-05
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REC_DesR-like | cd19930 | phosphoacceptor receiver (REC) domain of DesR and similar proteins; This group is composed of ... |
1-54 | 4.40e-05 | |||
phosphoacceptor receiver (REC) domain of DesR and similar proteins; This group is composed of Bacillus subtilis DesR, Streptococcus pneumoniae response regulator spr1814, and similar proteins, all containing an N-terminal REC domain and a C-terminal LuxR family helix-turn-helix (HTH) DNA-binding output domain. DesR is a response regulator that, together with its cognate sensor kinase DesK, comprises a two-component regulatory system that controls membrane fluidity. Phosphorylation of the REC domain of DesR is allosterically coupled to two distinct exposed surfaces of the protein, controlling noncanonical dimerization/tetramerization, cooperative activation, and DesK binding. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays. Pssm-ID: 381157 [Multi-domain] Cd Length: 117 Bit Score: 39.95 E-value: 4.40e-05
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GerE | COG5905 | Spore transcriptional regulator GerE (stand-alone HTH domain) [Cell cycle control, cell ... |
81-132 | 5.67e-05 | |||
Spore transcriptional regulator GerE (stand-alone HTH domain) [Cell cycle control, cell division, chromosome partitioning, Transcription]; Pssm-ID: 444607 [Multi-domain] Cd Length: 76 Bit Score: 38.79 E-value: 5.67e-05
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AtoC | COG2204 | DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, ... |
1-61 | 7.47e-05 | |||
DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains [Signal transduction mechanisms]; Pssm-ID: 441806 [Multi-domain] Cd Length: 418 Bit Score: 40.72 E-value: 7.47e-05
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OmpR | COG0745 | DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain ... |
1-93 | 1.05e-03 | |||
DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain [Signal transduction mechanisms, Transcription]; Pssm-ID: 440508 [Multi-domain] Cd Length: 204 Bit Score: 37.24 E-value: 1.05e-03
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MalT | COG2909 | ATP-, maltotriose- and DNA-dependent transcriptional regulator MalT [Transcription]; |
106-132 | 1.22e-03 | |||
ATP-, maltotriose- and DNA-dependent transcriptional regulator MalT [Transcription]; Pssm-ID: 442153 [Multi-domain] Cd Length: 184 Bit Score: 36.99 E-value: 1.22e-03
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fixJ | PRK09390 | response regulator FixJ; Provisional |
32-132 | 6.01e-03 | |||
response regulator FixJ; Provisional Pssm-ID: 181815 [Multi-domain] Cd Length: 202 Bit Score: 34.98 E-value: 6.01e-03
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REC_CheY | cd17542 | phosphoacceptor receiver (REC) domain of chemotaxis protein CheY; The chemotaxis response ... |
1-57 | 6.21e-03 | |||
phosphoacceptor receiver (REC) domain of chemotaxis protein CheY; The chemotaxis response regulator CheY contains a stand-alone REC domain. Chemotaxis is a behavior known for motile bacteria that directs their movement in response to chemical gradients. CheY is involved in transmitting sensory signals from chemoreceptors to the flagellar motors. Phosphorylated CheY interacts with the flagella switch components FliM and FliY, which causes counterclockwise rotation of the flagella, resulting in smooth swimming. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays. Pssm-ID: 381097 [Multi-domain] Cd Length: 117 Bit Score: 34.18 E-value: 6.21e-03
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REC | cd00156 | phosphoacceptor receiver (REC) domain of response regulators (RRs) and pseudo response ... |
1-42 | 6.96e-03 | |||
phosphoacceptor receiver (REC) domain of response regulators (RRs) and pseudo response regulators (PRRs); Two-component systems (TCSs) involving a sensor and a response regulator are used by bacteria to adapt to changing environments. Processes regulated by two-component systems in bacteria include sporulation, pathogenicity, virulence, chemotaxis, and membrane transport. Response regulators (RRs) share the common phosphoacceptor REC domain and different effector/output domains such as DNA, RNA, ligand-binding, protein-binding, or enzymatic domains. Response regulators regulate transcription, post-transcription or post-translation, or have functions such as methylesterases, adenylate or diguanylate cyclase, c-di-GMP-specific phosphodiesterases, histidine kinases, serine/threonine protein kinases, and protein phosphatases, depending on their output domains. The function of some output domains are still unknown. TCSs are found in all three domains of life - bacteria, archaea, and eukaryotes, however, the presence and abundance of particular RRs vary between the lineages. Archaea encode very few RRs with DNA-binding output domains; most are stand-alone REC domains. Among eukaryotes, TCSs are found primarily in protozoa, fungi, algae, and green plants. REC domains function as phosphorylation-mediated switches within RRs, but some also transfer phosphoryl groups in multistep phosphorelays. Pssm-ID: 381085 [Multi-domain] Cd Length: 99 Bit Score: 33.74 E-value: 6.96e-03
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Blast search parameters | ||||
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