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Conserved domains on  [gi|50513185|gb|AAT77785|]
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insulin growth factor-like family member 1 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
IGFL super family cl20614
Insulin growth factor-like family; This family includes the insulin growth factor-like ...
 34-86 4.48e-15

Insulin growth factor-like family; This family includes the insulin growth factor-like proteins. These proteins are potential ligands for the IGFLR1 cell membrane receptor.


The actual alignment was detected with superfamily member pfam14653:

Pssm-ID: 464239  Cd Length: 83  Bit Score: 64.40  E-value: 4.48e-15
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 50513185    34 LMLCQPHKRCGDKFYDPLQHCCYDDAVVPLARTQTCG-NCTFRVCFEQCCPWTF 86
Cdd:pfam14653   2 LWLCQPAPRCGDQPYNPCEQCCYDDTILPLNRTRPCGpNCTFWPCFELCCPESF 55
 
Name Accession Description Interval E-value
IGFL pfam14653
Insulin growth factor-like family; This family includes the insulin growth factor-like ...
 34-86 4.48e-15

Insulin growth factor-like family; This family includes the insulin growth factor-like proteins. These proteins are potential ligands for the IGFLR1 cell membrane receptor.


Pssm-ID: 464239  Cd Length: 83  Bit Score: 64.40  E-value: 4.48e-15
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 50513185    34 LMLCQPHKRCGDKFYDPLQHCCYDDAVVPLARTQTCG-NCTFRVCFEQCCPWTF 86
Cdd:pfam14653   2 LWLCQPAPRCGDQPYNPCEQCCYDDTILPLNRTRPCGpNCTFWPCFELCCPESF 55
 
Name Accession Description Interval E-value
IGFL pfam14653
Insulin growth factor-like family; This family includes the insulin growth factor-like ...
 34-86 4.48e-15

Insulin growth factor-like family; This family includes the insulin growth factor-like proteins. These proteins are potential ligands for the IGFLR1 cell membrane receptor.


Pssm-ID: 464239  Cd Length: 83  Bit Score: 64.40  E-value: 4.48e-15
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 50513185    34 LMLCQPHKRCGDKFYDPLQHCCYDDAVVPLARTQTCG-NCTFRVCFEQCCPWTF 86
Cdd:pfam14653   2 LWLCQPAPRCGDQPYNPCEQCCYDDTILPLNRTRPCGpNCTFWPCFELCCPESF 55
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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