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Conserved domains on  [gi|55832764|gb|AAV66895|]
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HERC6 splice variant [Homo sapiens]

Protein Classification

E3 ubiquitin-protein ligase HERC family protein( domain architecture ID 18804227)

E3 ubiquitin-protein ligase HERC (HECT and RCC1 domain) family protein similar to human E3 ISG15--protein ligase HERC5, the major E3 ligase for ISG15 conjugation, that functions as part of the ISGylation machinery that recognizes target proteins in a broad and relatively non-specific manner

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HECTc cd00078
HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It ...
 636-978 1.79e-135

HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ubiquitin molecules to the end of growing ubiquitin chains.


:

Pssm-ID: 238033 [Multi-domain]  Cd Length: 352  Bit Score: 410.80  E-value: 1.79e-135
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55832764 636 FILRVRRSRLVKDALRQLSQAEATDFCKVLVVEFINEICPESGGVSSEFFHCMFEEMTKPEYGMFMYPEMG-SCMWFPAK 714
Cdd:cd00078   1 LKITVRRDRILEDALRQLSKVSSSDLKKVLEVEFVGEEGIDAGGVTREFFTLVSKELFNPSYGLFRYTPDDsGLLYPNPS 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55832764 715 PKP---EKKRYFLFGMLCGLSLFNLNVANLPFPLALYKKLLDQKPSLEDLKELSPRLGKSLQEVLDDAADDIGDALCirF 791
Cdd:cd00078  81 SFAdedHLKLFRFLGRLLGKALYEGRLLDLPFSRAFYKKLLGKPLSLEDLEELDPELYKSLKELLDNDGDEDDLELT--F 158

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55832764 792 SIH-----WDQNDVDLIPNGISIPVDQTNKRDYVSKYIDYIFNVSVKAVYEEFQRGFYRVCEKEILRHFYPEELMTAIIG 866
Cdd:cd00078 159 TIEldssfGGAVTVELKPGGRDIPVTNENKEEYVDLYVDYRLNKGIEEQVEAFRDGFSEVIPEELLSLFTPEELELLICG 238

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55832764 867 NTDYDWKQFEQNSKYEQGYQKSHPTIQLFWKAFHKLTLDEKKKFLFFLTGRDRLHARGIQKMEIVFRCPET-FSERDHPT 945
Cdd:cd00078 239 SEDIDLEDLKKNTEYKGGYSSDSPTIQWFWEVLESFTNEERKKFLQFVTGSSRLPVGGFADLNPKFTIRRVgSPDDRLPT 318

                       330       340       350
                ....*....|....*....|....*....|...
gi 55832764 946 SITCHNILSLPKYSTMERMEEALQVAINNNRGF 978
Cdd:cd00078 319 AHTCFNLLKLPPYSSKEILREKLLYAINEGAGF 351
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 27-313 2.88e-68

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


:

Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 231.79  E-value: 2.88e-68
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55832764  27 QAASGERHSLLLLTNHRVLSCGDNSRGQLGRRGAQRGELPEPIQALETlIVDlVSCGKEHSLAVCHKGRVFAWGAGSEGQ 106
Cdd:COG5184   2 QVAAGGSHSCALKSDGTVWCWGDNSYGQLGDGTTTDRSTPVRVPGLSN-VVA-VAAGGDHTCALKADGTVWCWGNNSYGQ 79

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55832764 107 LGIGEfKEISFTPKKIMTLNDIKiiQVSCGHYHSLALSKDSQVFSWGKNSHGQLGLGkEFPSQASPQRVR-SLEGIplAQ 185
Cdd:COG5184  80 LGDGT-TTDRTTPVKVPGLTGVV--AVAAGYYHSCALKSDGTVWCWGDNSSGQLGDG-TTTNRLTPVQVDaGLSGV--VA 153

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55832764 186 VAAGGAHSFALSLCGTSFGWGSNSAGQLalsGRNVPVQSNKPLSVGALKnlGVVYISCGDAHTAVLTQDGKVFTFGDNRS 265
Cdd:COG5184 154 IAAGGYHTCALKSDGTVWCWGANSYGQL---GDGTTTDRPTPVQVGGLS--GVVAVAAGGDHSCALKSDGTVWCWGSNSS 228

                       250       260       270       280
                ....*....|....*....|....*....|....*....|....*...
gi 55832764 266 GQLGYSPTPEKRGPQLVERIDGlVSQIDCGSYHTLAyVHTTGQVVSFG 313
Cdd:COG5184 229 GQLGDGTTTDRATPVQVAGLTG-VVAIAAGGSHTCA-LKSDGTVWCWG 274
 
Name Accession Description Interval E-value
HECTc cd00078
HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It ...
 636-978 1.79e-135

HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ubiquitin molecules to the end of growing ubiquitin chains.


Pssm-ID: 238033 [Multi-domain]  Cd Length: 352  Bit Score: 410.80  E-value: 1.79e-135
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55832764 636 FILRVRRSRLVKDALRQLSQAEATDFCKVLVVEFINEICPESGGVSSEFFHCMFEEMTKPEYGMFMYPEMG-SCMWFPAK 714
Cdd:cd00078   1 LKITVRRDRILEDALRQLSKVSSSDLKKVLEVEFVGEEGIDAGGVTREFFTLVSKELFNPSYGLFRYTPDDsGLLYPNPS 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55832764 715 PKP---EKKRYFLFGMLCGLSLFNLNVANLPFPLALYKKLLDQKPSLEDLKELSPRLGKSLQEVLDDAADDIGDALCirF 791
Cdd:cd00078  81 SFAdedHLKLFRFLGRLLGKALYEGRLLDLPFSRAFYKKLLGKPLSLEDLEELDPELYKSLKELLDNDGDEDDLELT--F 158

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55832764 792 SIH-----WDQNDVDLIPNGISIPVDQTNKRDYVSKYIDYIFNVSVKAVYEEFQRGFYRVCEKEILRHFYPEELMTAIIG 866
Cdd:cd00078 159 TIEldssfGGAVTVELKPGGRDIPVTNENKEEYVDLYVDYRLNKGIEEQVEAFRDGFSEVIPEELLSLFTPEELELLICG 238

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55832764 867 NTDYDWKQFEQNSKYEQGYQKSHPTIQLFWKAFHKLTLDEKKKFLFFLTGRDRLHARGIQKMEIVFRCPET-FSERDHPT 945
Cdd:cd00078 239 SEDIDLEDLKKNTEYKGGYSSDSPTIQWFWEVLESFTNEERKKFLQFVTGSSRLPVGGFADLNPKFTIRRVgSPDDRLPT 318

                       330       340       350
                ....*....|....*....|....*....|...
gi 55832764 946 SITCHNILSLPKYSTMERMEEALQVAINNNRGF 978
Cdd:cd00078 319 AHTCFNLLKLPPYSSKEILREKLLYAINEGAGF 351
HECT pfam00632
HECT-domain (ubiquitin-transferase); The name HECT comes from Homologous to the E6-AP Carboxyl ...
 690-978 3.05e-78

HECT-domain (ubiquitin-transferase); The name HECT comes from Homologous to the E6-AP Carboxyl Terminus.


Pssm-ID: 459880  Cd Length: 304  Bit Score: 257.54  E-value: 3.05e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55832764   690 EEMTKPEYGMFMYPEMGSC-MWF----PAKPKPEKKRYF-LFGMLCGLSLFNLNVANLPFPLALYKKLLDQKPSLEDLKE 763
Cdd:pfam00632   5 KELFDPNYGLFEYETEDDRtYWFnpssSESPDLELLDYFkFLGKLLGKAIYNGILLDLPFPPFFYKKLLGEPLTLEDLES 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55832764   764 LSPRLGKSLQEvLDDAADDIGDALCIRFSI--HWDQNDVDLIPNGISIPVDQTNKRDYVSKYIDYIFNVSVKAVYEEFQR 841
Cdd:pfam00632  85 IDPELYKSLKS-LLNMDNDDDEDLGLTFTIpvFGESKTIELIPNGRNIPVTNENKEEYIRLYVDYRLNKSIEPQLEAFRK 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55832764   842 GFYRVCEKEILRHFYPEELMTAIIGNTDYDWKQFEQNSKYEQGYQKSHPTIQLFWKAFHKLTLDEKKKFLFFLTGRDRLH 921
Cdd:pfam00632 164 GFYSVIPKEALSLFTPEELELLICGSPEIDVEDLKKNTEYDGGYTKNSPTIQWFWEILEEFSPEQRRLFLKFVTGSSRLP 243

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 55832764   922 ARGIQKMEIVFRCPETFSERDH-PTSITCHNILSLPKYSTMERMEEALQVAINNNRGF 978
Cdd:pfam00632 244 VGGFKSLPKFTIVRKGGDDDDRlPTAHTCFNRLKLPDYSSKEILKEKLLIAIEEGEGF 301
HECTc smart00119
Domain Homologous to E6-AP Carboxyl Terminus with; E3 ubiquitin-protein ligases. Can bind to ...
 663-978 1.50e-74

Domain Homologous to E6-AP Carboxyl Terminus with; E3 ubiquitin-protein ligases. Can bind to E2 enzymes.


Pssm-ID: 214523  Cd Length: 328  Bit Score: 248.69  E-value: 1.50e-74
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55832764    663 KVLVVEFINEICPESGGVSSEFFHCMFEEMTKPEYGMFMYPEMGSCMWFPAKP---KPEKKRYF-LFGMLCGLSLFNLNV 738
Cdd:smart00119   5 RVLEIEFEGEEGLDGGGVTREFFFLLSKELFNPDYGLFRYSPNDYLLYPNPRSgfaNEEHLSYFrFIGRVLGKALYDNRL 84

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55832764    739 ANLPFPLALYKKLLDQKPSLEDLKELSPRLGKSLQEVLDDAADDIGDALCirFSIHwDQND------VDLIPNGISIPVD 812
Cdd:smart00119  85 LDLFFARPFYKKLLGKPVTLHDLESLDPELYKSLKWLLLNNDTSEELDLT--FSIV-LTSEfgqvkvVELKPGGSNIPVT 161

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55832764    813 QTNKRDYVSKYIDYIFNVSVKAVYEEFQRGFYRVCEKEILRHFYPEELMTAIIGNTDYDWKQFEQNSKYEQGYQKSHPTI 892
Cdd:smart00119 162 EENKKEYVHLVIEYRLNKGIEKQLEAFREGFSEVIPENLLKLFDPEELELLICGSPEIDVDDLKSNTEYKGGYSANSQTI 241

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55832764    893 QLFWKAFHKLTLDEKKKFLFFLTGRDRLHARGIQKMEIVFRCPETFSERDH-PTSITCHNILSLPKYSTMERMEEALQVA 971
Cdd:smart00119 242 KWFWEVVESFTNEERRKLLQFVTGSSRLPVGGFAALSPKFTIRKAGSDDERlPTAHTCFNRLKLPPYSSKEILREKLLLA 321


                   ....*..
gi 55832764    972 INNNRGF 978
Cdd:smart00119 322 INEGKGF 328
HUL4 COG5021
Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones];
334-978 4.46e-69

Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 227354 [Multi-domain]  Cd Length: 872  Bit Score: 247.76  E-value: 4.46e-69
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55832764 334 ISCLISAEDFVDVQVKHifagtyanFVTTHQDTSSTRA----PGKTLPEISR-ISQSMAEKWIAVK-------RRSTEHE 401
Cdd:COG5021 192 VKSRKLAVSNVEKSEPD--------NVLFGLPYRSALTmrtnFLKLDTGNLSgEVQALLARYISIKlvikklyLGPGPDA 263

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55832764 402 MAKSEIRMIFSSPACLTaSFLKKRGTGETT--------------------SIDVDLEMARDTFKKLTKKEWISSMITTCL 461
Cdd:COG5021 264 SSRISTLIIRLSNTNLN-RRLSYILSHSSFedsllrlnslfstradsfgrTYYLDHDRILTQYSRPLLEETLGESTSFLV 342

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55832764 462 EDDLLRALPCHSPHQEALSvflllPECPVMHD-SKNWKNLVVPFAKAVCEMSKQSLQVLKKCWAFLQESSL-------NP 533
Cdd:COG5021 343 VNNDDSSSIKDLPHQVGSN-----PFLEAHPEfSELLKNQSRGTTRDFRNKPTGWSSSIEDLGQFLFSDFLtssstyeDL 417

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55832764 534 LIQMLKAAIISQLLHQTKTEQDHCNVKALLGM-----MKELHKVNKANCRLPENTFNINELSNLLNFYIDRGRQLFRDNh 608
Cdd:COG5021 418 RREQLGRESDESFYVASNVQQQRASREGPLLSgwktrLNNLYRFYFVEHRKKTLTKNDSRLGSFISLNKLDIRRIKEDK- 496

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55832764 609 lmSEKKAYMLmhetiLQKKDEFPPspRFILRVRRSRLVKDALRQLSQAEATDFCKVLVVEFINEICPESGGVSSEFFHCM 688
Cdd:COG5021 497 --RRKLFYSL-----KQKAKIFDP--YLHIKVRRDRVFEDSYREIMDESGDDLKKTLEIEFVGEEGIDAGGLTREWLFLL 567

                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55832764 689 FEEMTKPEYGMFMYPEMGSCMWFPAKP---KPEKKRYFLF-GMLCGLSLFNLNVANLPFPLALYKKLLDQKPSLEDLKEL 764
Cdd:COG5021 568 SKEMFNPDYGLFEYITEDLYTLPINPLssiNPEHLSYFKFlGRVIGKAIYDSRILDVQFSKAFYKKLLGKPVSLVDLESL 647

                       490       500       510       520       530       540       550       560
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55832764 765 SPRLGKSLQEVLDDAADDIGdaLCIRFSI-HWDQND---VDLIPNGISIPVDQTNKRDYVSKYIDYIFNVSVKAVYEEFQ 840
Cdd:COG5021 648 DPELYRSLVWLLNNDIDETI--LDLTFTVeDDSFGEsrtVELIPNGRNISVTNENKKEYVKKVVDYKLNKRVEKQFSAFK 725

                       570       580       590       600       610       620       630       640
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55832764 841 RGFYRVCEKEILRHFYPEELMTAIIG-NTDYDWKQFEQNSKYeQGYQKSHPTIQLFWKAFHKLTLDEKKKFLFFLTGRDR 919
Cdd:COG5021 726 SGFSEIIPPDLLQIFDESELELLIGGiPEDIDIDDWKSNTAY-HGYTEDSPIIVWFWEIISEFDFEERAKLLQFVTGTSR 804

                       650       660       670       680       690       700
                ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 55832764 920 LHARGIQ----KMEIVFRCPETFSERDH--PTSITCHNILSLPKYSTMERMEEALQVAINNNRGF 978
Cdd:COG5021 805 IPINGFKdlqgSDGVRKFTIEKGGTDDDrlPSAHTCFNRLKLPEYSSKEKLRSKLLTAINEGAGF 869
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 27-313 2.88e-68

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 231.79  E-value: 2.88e-68
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55832764  27 QAASGERHSLLLLTNHRVLSCGDNSRGQLGRRGAQRGELPEPIQALETlIVDlVSCGKEHSLAVCHKGRVFAWGAGSEGQ 106
Cdd:COG5184   2 QVAAGGSHSCALKSDGTVWCWGDNSYGQLGDGTTTDRSTPVRVPGLSN-VVA-VAAGGDHTCALKADGTVWCWGNNSYGQ 79

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55832764 107 LGIGEfKEISFTPKKIMTLNDIKiiQVSCGHYHSLALSKDSQVFSWGKNSHGQLGLGkEFPSQASPQRVR-SLEGIplAQ 185
Cdd:COG5184  80 LGDGT-TTDRTTPVKVPGLTGVV--AVAAGYYHSCALKSDGTVWCWGDNSSGQLGDG-TTTNRLTPVQVDaGLSGV--VA 153

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55832764 186 VAAGGAHSFALSLCGTSFGWGSNSAGQLalsGRNVPVQSNKPLSVGALKnlGVVYISCGDAHTAVLTQDGKVFTFGDNRS 265
Cdd:COG5184 154 IAAGGYHTCALKSDGTVWCWGANSYGQL---GDGTTTDRPTPVQVGGLS--GVVAVAAGGDHSCALKSDGTVWCWGSNSS 228

                       250       260       270       280
                ....*....|....*....|....*....|....*....|....*...
gi 55832764 266 GQLGYSPTPEKRGPQLVERIDGlVSQIDCGSYHTLAyVHTTGQVVSFG 313
Cdd:COG5184 229 GQLGDGTTTDRATPVQVAGLTG-VVAIAAGGSHTCA-LKSDGTVWCWG 274
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
93-143 1.41e-16

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 74.48  E-value: 1.41e-16
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 55832764    93 KGRVFAWGAGSEGQLGIGEFKEiSFTPKKIMTLNDIKIIQVSCGHYHSLAL 143
Cdd:pfam00415   1 DGRVYTWGRNDYGQLGLGTTEN-VLVPQKVEGLSGNKVVQVACGGDHTVAL 50
 
Name Accession Description Interval E-value
HECTc cd00078
HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It ...
 636-978 1.79e-135

HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ubiquitin molecules to the end of growing ubiquitin chains.


Pssm-ID: 238033 [Multi-domain]  Cd Length: 352  Bit Score: 410.80  E-value: 1.79e-135
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55832764 636 FILRVRRSRLVKDALRQLSQAEATDFCKVLVVEFINEICPESGGVSSEFFHCMFEEMTKPEYGMFMYPEMG-SCMWFPAK 714
Cdd:cd00078   1 LKITVRRDRILEDALRQLSKVSSSDLKKVLEVEFVGEEGIDAGGVTREFFTLVSKELFNPSYGLFRYTPDDsGLLYPNPS 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55832764 715 PKP---EKKRYFLFGMLCGLSLFNLNVANLPFPLALYKKLLDQKPSLEDLKELSPRLGKSLQEVLDDAADDIGDALCirF 791
Cdd:cd00078  81 SFAdedHLKLFRFLGRLLGKALYEGRLLDLPFSRAFYKKLLGKPLSLEDLEELDPELYKSLKELLDNDGDEDDLELT--F 158

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55832764 792 SIH-----WDQNDVDLIPNGISIPVDQTNKRDYVSKYIDYIFNVSVKAVYEEFQRGFYRVCEKEILRHFYPEELMTAIIG 866
Cdd:cd00078 159 TIEldssfGGAVTVELKPGGRDIPVTNENKEEYVDLYVDYRLNKGIEEQVEAFRDGFSEVIPEELLSLFTPEELELLICG 238

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55832764 867 NTDYDWKQFEQNSKYEQGYQKSHPTIQLFWKAFHKLTLDEKKKFLFFLTGRDRLHARGIQKMEIVFRCPET-FSERDHPT 945
Cdd:cd00078 239 SEDIDLEDLKKNTEYKGGYSSDSPTIQWFWEVLESFTNEERKKFLQFVTGSSRLPVGGFADLNPKFTIRRVgSPDDRLPT 318

                       330       340       350
                ....*....|....*....|....*....|...
gi 55832764 946 SITCHNILSLPKYSTMERMEEALQVAINNNRGF 978
Cdd:cd00078 319 AHTCFNLLKLPPYSSKEILREKLLYAINEGAGF 351
HECT pfam00632
HECT-domain (ubiquitin-transferase); The name HECT comes from Homologous to the E6-AP Carboxyl ...
 690-978 3.05e-78

HECT-domain (ubiquitin-transferase); The name HECT comes from Homologous to the E6-AP Carboxyl Terminus.


Pssm-ID: 459880  Cd Length: 304  Bit Score: 257.54  E-value: 3.05e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55832764   690 EEMTKPEYGMFMYPEMGSC-MWF----PAKPKPEKKRYF-LFGMLCGLSLFNLNVANLPFPLALYKKLLDQKPSLEDLKE 763
Cdd:pfam00632   5 KELFDPNYGLFEYETEDDRtYWFnpssSESPDLELLDYFkFLGKLLGKAIYNGILLDLPFPPFFYKKLLGEPLTLEDLES 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55832764   764 LSPRLGKSLQEvLDDAADDIGDALCIRFSI--HWDQNDVDLIPNGISIPVDQTNKRDYVSKYIDYIFNVSVKAVYEEFQR 841
Cdd:pfam00632  85 IDPELYKSLKS-LLNMDNDDDEDLGLTFTIpvFGESKTIELIPNGRNIPVTNENKEEYIRLYVDYRLNKSIEPQLEAFRK 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55832764   842 GFYRVCEKEILRHFYPEELMTAIIGNTDYDWKQFEQNSKYEQGYQKSHPTIQLFWKAFHKLTLDEKKKFLFFLTGRDRLH 921
Cdd:pfam00632 164 GFYSVIPKEALSLFTPEELELLICGSPEIDVEDLKKNTEYDGGYTKNSPTIQWFWEILEEFSPEQRRLFLKFVTGSSRLP 243

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 55832764   922 ARGIQKMEIVFRCPETFSERDH-PTSITCHNILSLPKYSTMERMEEALQVAINNNRGF 978
Cdd:pfam00632 244 VGGFKSLPKFTIVRKGGDDDDRlPTAHTCFNRLKLPDYSSKEILKEKLLIAIEEGEGF 301
HECTc smart00119
Domain Homologous to E6-AP Carboxyl Terminus with; E3 ubiquitin-protein ligases. Can bind to ...
 663-978 1.50e-74

Domain Homologous to E6-AP Carboxyl Terminus with; E3 ubiquitin-protein ligases. Can bind to E2 enzymes.


Pssm-ID: 214523  Cd Length: 328  Bit Score: 248.69  E-value: 1.50e-74
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55832764    663 KVLVVEFINEICPESGGVSSEFFHCMFEEMTKPEYGMFMYPEMGSCMWFPAKP---KPEKKRYF-LFGMLCGLSLFNLNV 738
Cdd:smart00119   5 RVLEIEFEGEEGLDGGGVTREFFFLLSKELFNPDYGLFRYSPNDYLLYPNPRSgfaNEEHLSYFrFIGRVLGKALYDNRL 84

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55832764    739 ANLPFPLALYKKLLDQKPSLEDLKELSPRLGKSLQEVLDDAADDIGDALCirFSIHwDQND------VDLIPNGISIPVD 812
Cdd:smart00119  85 LDLFFARPFYKKLLGKPVTLHDLESLDPELYKSLKWLLLNNDTSEELDLT--FSIV-LTSEfgqvkvVELKPGGSNIPVT 161

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55832764    813 QTNKRDYVSKYIDYIFNVSVKAVYEEFQRGFYRVCEKEILRHFYPEELMTAIIGNTDYDWKQFEQNSKYEQGYQKSHPTI 892
Cdd:smart00119 162 EENKKEYVHLVIEYRLNKGIEKQLEAFREGFSEVIPENLLKLFDPEELELLICGSPEIDVDDLKSNTEYKGGYSANSQTI 241

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55832764    893 QLFWKAFHKLTLDEKKKFLFFLTGRDRLHARGIQKMEIVFRCPETFSERDH-PTSITCHNILSLPKYSTMERMEEALQVA 971
Cdd:smart00119 242 KWFWEVVESFTNEERRKLLQFVTGSSRLPVGGFAALSPKFTIRKAGSDDERlPTAHTCFNRLKLPPYSSKEILREKLLLA 321


                   ....*..
gi 55832764    972 INNNRGF 978
Cdd:smart00119 322 INEGKGF 328
HUL4 COG5021
Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones];
334-978 4.46e-69

Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 227354 [Multi-domain]  Cd Length: 872  Bit Score: 247.76  E-value: 4.46e-69
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55832764 334 ISCLISAEDFVDVQVKHifagtyanFVTTHQDTSSTRA----PGKTLPEISR-ISQSMAEKWIAVK-------RRSTEHE 401
Cdd:COG5021 192 VKSRKLAVSNVEKSEPD--------NVLFGLPYRSALTmrtnFLKLDTGNLSgEVQALLARYISIKlvikklyLGPGPDA 263

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55832764 402 MAKSEIRMIFSSPACLTaSFLKKRGTGETT--------------------SIDVDLEMARDTFKKLTKKEWISSMITTCL 461
Cdd:COG5021 264 SSRISTLIIRLSNTNLN-RRLSYILSHSSFedsllrlnslfstradsfgrTYYLDHDRILTQYSRPLLEETLGESTSFLV 342

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55832764 462 EDDLLRALPCHSPHQEALSvflllPECPVMHD-SKNWKNLVVPFAKAVCEMSKQSLQVLKKCWAFLQESSL-------NP 533
Cdd:COG5021 343 VNNDDSSSIKDLPHQVGSN-----PFLEAHPEfSELLKNQSRGTTRDFRNKPTGWSSSIEDLGQFLFSDFLtssstyeDL 417

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55832764 534 LIQMLKAAIISQLLHQTKTEQDHCNVKALLGM-----MKELHKVNKANCRLPENTFNINELSNLLNFYIDRGRQLFRDNh 608
Cdd:COG5021 418 RREQLGRESDESFYVASNVQQQRASREGPLLSgwktrLNNLYRFYFVEHRKKTLTKNDSRLGSFISLNKLDIRRIKEDK- 496

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55832764 609 lmSEKKAYMLmhetiLQKKDEFPPspRFILRVRRSRLVKDALRQLSQAEATDFCKVLVVEFINEICPESGGVSSEFFHCM 688
Cdd:COG5021 497 --RRKLFYSL-----KQKAKIFDP--YLHIKVRRDRVFEDSYREIMDESGDDLKKTLEIEFVGEEGIDAGGLTREWLFLL 567

                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55832764 689 FEEMTKPEYGMFMYPEMGSCMWFPAKP---KPEKKRYFLF-GMLCGLSLFNLNVANLPFPLALYKKLLDQKPSLEDLKEL 764
Cdd:COG5021 568 SKEMFNPDYGLFEYITEDLYTLPINPLssiNPEHLSYFKFlGRVIGKAIYDSRILDVQFSKAFYKKLLGKPVSLVDLESL 647

                       490       500       510       520       530       540       550       560
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55832764 765 SPRLGKSLQEVLDDAADDIGdaLCIRFSI-HWDQND---VDLIPNGISIPVDQTNKRDYVSKYIDYIFNVSVKAVYEEFQ 840
Cdd:COG5021 648 DPELYRSLVWLLNNDIDETI--LDLTFTVeDDSFGEsrtVELIPNGRNISVTNENKKEYVKKVVDYKLNKRVEKQFSAFK 725

                       570       580       590       600       610       620       630       640
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55832764 841 RGFYRVCEKEILRHFYPEELMTAIIG-NTDYDWKQFEQNSKYeQGYQKSHPTIQLFWKAFHKLTLDEKKKFLFFLTGRDR 919
Cdd:COG5021 726 SGFSEIIPPDLLQIFDESELELLIGGiPEDIDIDDWKSNTAY-HGYTEDSPIIVWFWEIISEFDFEERAKLLQFVTGTSR 804

                       650       660       670       680       690       700
                ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 55832764 920 LHARGIQ----KMEIVFRCPETFSERDH--PTSITCHNILSLPKYSTMERMEEALQVAINNNRGF 978
Cdd:COG5021 805 IPINGFKdlqgSDGVRKFTIEKGGTDDDrlPSAHTCFNRLKLPEYSSKEKLRSKLLTAINEGAGF 869
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 27-313 2.88e-68

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 231.79  E-value: 2.88e-68
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55832764  27 QAASGERHSLLLLTNHRVLSCGDNSRGQLGRRGAQRGELPEPIQALETlIVDlVSCGKEHSLAVCHKGRVFAWGAGSEGQ 106
Cdd:COG5184   2 QVAAGGSHSCALKSDGTVWCWGDNSYGQLGDGTTTDRSTPVRVPGLSN-VVA-VAAGGDHTCALKADGTVWCWGNNSYGQ 79

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55832764 107 LGIGEfKEISFTPKKIMTLNDIKiiQVSCGHYHSLALSKDSQVFSWGKNSHGQLGLGkEFPSQASPQRVR-SLEGIplAQ 185
Cdd:COG5184  80 LGDGT-TTDRTTPVKVPGLTGVV--AVAAGYYHSCALKSDGTVWCWGDNSSGQLGDG-TTTNRLTPVQVDaGLSGV--VA 153

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55832764 186 VAAGGAHSFALSLCGTSFGWGSNSAGQLalsGRNVPVQSNKPLSVGALKnlGVVYISCGDAHTAVLTQDGKVFTFGDNRS 265
Cdd:COG5184 154 IAAGGYHTCALKSDGTVWCWGANSYGQL---GDGTTTDRPTPVQVGGLS--GVVAVAAGGDHSCALKSDGTVWCWGSNSS 228

                       250       260       270       280
                ....*....|....*....|....*....|....*....|....*...
gi 55832764 266 GQLGYSPTPEKRGPQLVERIDGlVSQIDCGSYHTLAyVHTTGQVVSFG 313
Cdd:COG5184 229 GQLGDGTTTDRATPVQVAGLTG-VVAIAAGGSHTCA-LKSDGTVWCWG 274
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 3-315 8.24e-67

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 227.94  E-value: 8.24e-67
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55832764   3 FCWGADSR-ELQRRRTAGSPGAELL-------QAASGERHSLLLLTNHRVLSCGDNSRGQLGRRGAQRGELPEPIQALET 74
Cdd:COG5184  20 WCWGDNSYgQLGDGTTTDRSTPVRVpglsnvvAVAAGGDHTCALKADGTVWCWGNNSYGQLGDGTTTDRTTPVKVPGLTG 99

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55832764  75 liVDLVSCGKEHSLAVCHKGRVFAWGAGSEGQLGIGEFKEiSFTPKKImTLNDIKIIQVSCGHYHSLALSKDSQVFSWGK 154
Cdd:COG5184 100 --VVAVAAGYYHSCALKSDGTVWCWGDNSSGQLGDGTTTN-RLTPVQV-DAGLSGVVAIAAGGYHTCALKSDGTVWCWGA 175

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55832764 155 NSHGQLGLGkEFPSQASPQRVRSLEGIplAQVAAGGAHSFALSLCGTSFGWGSNSAGQLalsGRNVPVQSNKPLSVGALK 234
Cdd:COG5184 176 NSYGQLGDG-TTTDRPTPVQVGGLSGV--VAVAAGGDHSCALKSDGTVWCWGSNSSGQL---GDGTTTDRATPVQVAGLT 249

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55832764 235 NlgVVYISCGDAHTAVLTQDGKVFTFGDNRSGQLGYSPTPEKRGPQLVERIDGlVSQIDCGSYHTLAyVHTTGQVVSFGH 314
Cdd:COG5184 250 G--VVAIAAGGSHTCALKSDGTVWCWGDNSYGQLGDGTTTDRSTPVKVPGLSG-VVAVAAGSSHTCA-LLTDGTVWCWGD 325


                .
gi 55832764 315 G 315
Cdd:COG5184 326 N 326
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 3-280 2.88e-59

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 206.75  E-value: 2.88e-59
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55832764   3 FCWGADSR------ELQRRRT----AGSPGAEllQAASGERHSLLLLTNHRVLSCGDNSRGQLGRRGAQRGELPEPIQAL 72
Cdd:COG5184  70 WCWGNNSYgqlgdgTTTDRTTpvkvPGLTGVV--AVAAGYYHSCALKSDGTVWCWGDNSSGQLGDGTTTNRLTPVQVDAG 147

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55832764  73 ETLIVDlVSCGKEHSLAVCHKGRVFAWGAGSEGQLGIGEFKEISfTPKKIMTLNDIkiIQVSCGHYHSLALSKDSQVFSW 152
Cdd:COG5184 148 LSGVVA-IAAGGYHTCALKSDGTVWCWGANSYGQLGDGTTTDRP-TPVQVGGLSGV--VAVAAGGDHSCALKSDGTVWCW 223

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55832764 153 GKNSHGQLGLGkEFPSQASPQRVRSLEGIplAQVAAGGAHSFALSLCGTSFGWGSNSAGQLalsGRNVPVQSNKPLSVGA 232
Cdd:COG5184 224 GSNSSGQLGDG-TTTDRATPVQVAGLTGV--VAIAAGGSHTCALKSDGTVWCWGDNSYGQL---GDGTTTDRSTPVKVPG 297

                       250       260       270       280
                ....*....|....*....|....*....|....*....|....*...
gi 55832764 233 LKNlgVVYISCGDAHTAVLTQDGKVFTFGDNRSGQLGYSPTPEKRGPQ 280
Cdd:COG5184 298 LSG--VVAVAAGSSHTCALLTDGTVWCWGDNAYGQLGDGTTTDRSTPV 343
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 131-317 5.22e-42

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 157.45  E-value: 5.22e-42
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55832764 131 IQVSCGHYHSLALSKDSQVFSWGKNSHGQLGLGKEFPSqASPQRVRSLEGIplAQVAAGGAHSFALSLCGTSFGWGSNSA 210
Cdd:COG5184   1 TQVAAGGSHSCALKSDGTVWCWGDNSYGQLGDGTTTDR-STPVRVPGLSNV--VAVAAGGDHTCALKADGTVWCWGNNSY 77

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55832764 211 GQLalsGRNVPVQSNKPLSVGALKNlgVVYISCGDAHTAVLTQDGKVFTFGDNRSGQLGYSPTPEKRGPQLVERIDGLVS 290
Cdd:COG5184  78 GQL---GDGTTTDRTTPVKVPGLTG--VVAVAAGYYHSCALKSDGTVWCWGDNSSGQLGDGTTTNRLTPVQVDAGLSGVV 152

                       170       180
                ....*....|....*....|....*..
gi 55832764 291 QIDCGSYHTLAyVHTTGQVVSFGHGPS 317
Cdd:COG5184 153 AIAAGGYHTCA-LKSDGTVWCWGANSY 178
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
93-143 1.41e-16

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 74.48  E-value: 1.41e-16
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 55832764    93 KGRVFAWGAGSEGQLGIGEFKEiSFTPKKIMTLNDIKIIQVSCGHYHSLAL 143
Cdd:pfam00415   1 DGRVYTWGRNDYGQLGLGTTEN-VLVPQKVEGLSGNKVVQVACGGDHTVAL 50
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
146-196 3.14e-14

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 67.54  E-value: 3.14e-14
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 55832764   146 DSQVFSWGKNSHGQLGLGKEFpSQASPQRVRSLEGIPLAQVAAGGAHSFAL 196
Cdd:pfam00415   1 DGRVYTWGRNDYGQLGLGTTE-NVLVPQKVEGLSGNKVVQVACGGDHTVAL 50
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
254-301 2.88e-10

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 56.37  E-value: 2.88e-10
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 55832764   254 DGKVFTFGDNRSGQLGYSPTPEKRGPQLVERIDGL-VSQIDCGSYHTLA 301
Cdd:pfam00415   1 DGRVYTWGRNDYGQLGLGTTENVLVPQKVEGLSGNkVVQVACGGDHTVA 49
RCC1_2 pfam13540
Regulator of chromosome condensation (RCC1) repeat;
130-159 1.34e-09

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 463914 [Multi-domain]  Cd Length: 30  Bit Score: 53.97  E-value: 1.34e-09
                          10        20        30
                  ....*....|....*....|....*....|
gi 55832764   130 IIQVSCGHYHSLALSKDSQVFSWGKNSHGQ 159
Cdd:pfam13540   1 VVSVAAGDNHTLALTSDGRVYCWGDNSYGQ 30
RCC1_2 pfam13540
Regulator of chromosome condensation (RCC1) repeat;
238-267 7.32e-09

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 463914 [Multi-domain]  Cd Length: 30  Bit Score: 52.04  E-value: 7.32e-09
                          10        20        30
                  ....*....|....*....|....*....|
gi 55832764   238 VVYISCGDAHTAVLTQDGKVFTFGDNRSGQ 267
Cdd:pfam13540   1 VVSVAAGDNHTLALTSDGRVYCWGDNSYGQ 30
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
203-251 4.96e-08

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 50.21  E-value: 4.96e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 55832764   203 FGWGSNSAGQLalsGRNVPVQSNKPLSVGALKNLGVVYISCGDAHTAVL 251
Cdd:pfam00415   5 YTWGRNDYGQL---GLGTTENVLVPQKVEGLSGNKVVQVACGGDHTVAL 50
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
41-90 6.28e-07

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 47.13  E-value: 6.28e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 55832764    41 NHRVLSCGDNSRGQLGRRGAQRGELPEPIQALETLIVDLVSCGKEHSLAV 90
Cdd:pfam00415   1 DGRVYTWGRNDYGQLGLGTTENVLVPQKVEGLSGNKVVQVACGGDHTVAL 50
RCC1_2 pfam13540
Regulator of chromosome condensation (RCC1) repeat;
27-54 2.45e-05

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 463914 [Multi-domain]  Cd Length: 30  Bit Score: 42.03  E-value: 2.45e-05
                          10        20
                  ....*....|....*....|....*...
gi 55832764    27 QAASGERHSLLLLTNHRVLSCGDNSRGQ 54
Cdd:pfam13540   3 SVAAGDNHTLALTSDGRVYCWGDNSYGQ 30
RCC1_2 pfam13540
Regulator of chromosome condensation (RCC1) repeat;
77-106 9.89e-05

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 463914 [Multi-domain]  Cd Length: 30  Bit Score: 40.10  E-value: 9.89e-05
                          10        20        30
                  ....*....|....*....|....*....|
gi 55832764    77 VDLVSCGKEHSLAVCHKGRVFAWGAGSEGQ 106
Cdd:pfam13540   1 VVSVAAGDNHTLALTSDGRVYCWGDNSYGQ 30
RCC1_2 pfam13540
Regulator of chromosome condensation (RCC1) repeat;
184-212 1.46e-04

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 463914 [Multi-domain]  Cd Length: 30  Bit Score: 39.71  E-value: 1.46e-04
                          10        20
                  ....*....|....*....|....*....
gi 55832764   184 AQVAAGGAHSFALSLCGTSFGWGSNSAGQ 212
Cdd:pfam13540   2 VSVAAGDNHTLALTSDGRVYCWGDNSYGQ 30
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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