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Conserved domains on  [gi|77389811|gb|ABA80995|]
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ABC Fe3+-siderophores transporter, inner membrane subunit [Cereibacter sphaeroides 2.4.1]

Protein Classification

FecCD family ABC transporter permease( domain architecture ID 10001816)

FecCD family ABC transporter permease such as iron ABC transporter permease, which is the transmembrane subunit (TM) found in a periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporter involved in the import of iron and iron-containing compounds

CATH:  1.10.3470.10
Gene Ontology:  GO:0140359|GO:0042626
PubMed:  25750732|24638992
SCOP:  4002900
TCDB:  3.A.1

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
FepD COG0609
ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and ...
 31-341 8.03e-79

ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism];


:

Pssm-ID: 440374  Cd Length: 306  Bit Score: 243.05  E-value: 8.03e-79
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77389811  31 VVIGETPLPLPTVAATFAnriwgaGLAVDPIEAGIVWNYRLPRTLVAAACGAGLALSGVVLQSLVRNALADPYLLGVSAG 110
Cdd:COG0609   2 LSLGAVPISLSDVLRALL------GPDGDPTADLIVWDLRLPRVLLALLVGAALAVAGALMQGLTRNPLADPGILGVSSG 75

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77389811 111 ASTGAVAVAILGVGGGLVGLSAGAF-GGALLAFALVALLARAAGGGSATLVLAGIAGSQLFNALTSFFIARsASAEQARG 189
Cdd:COG0609  76 AALGAVLAIVLGGGLSALGLPLAAFlGALLAALLVYLLARRGGGLSPLRLVLAGVAVSALFSALTSLLLLL-ADPEQLRS 154

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77389811 190 IMFWLLGNLSGVRWPDVTLALPAALAGLLLCLWHIRAMDAFSFGTQSAKALGVPVRRVQAVLIGITTLMTAVMVSLVGSI 269
Cdd:COG0609 155 IVFWLMGSLAGASWDDVLLLLPVLLIGLLLALLLARALNALALGDETARSLGVNVERLRLLLLLLAALLTGAAVAVAGPI 234

                       250       260       270       280       290       300       310
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 77389811 270 GFVGLVVPHAVRLVAGPRHGALVPWAALAGAIFLIAADVVSRVLIAGQVVPIGVVTALVGAPGFALILIRNR 341
Cdd:COG0609 235 GFVGLVVPHIARLLVGPDHRRLLPASALLGALLLLLADTLARTILAPAELPVGIVTALIGAPFFLYLLRRRR 306
 
Name Accession Description Interval E-value
FepD COG0609
ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and ...
 31-341 8.03e-79

ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440374  Cd Length: 306  Bit Score: 243.05  E-value: 8.03e-79
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77389811  31 VVIGETPLPLPTVAATFAnriwgaGLAVDPIEAGIVWNYRLPRTLVAAACGAGLALSGVVLQSLVRNALADPYLLGVSAG 110
Cdd:COG0609   2 LSLGAVPISLSDVLRALL------GPDGDPTADLIVWDLRLPRVLLALLVGAALAVAGALMQGLTRNPLADPGILGVSSG 75

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77389811 111 ASTGAVAVAILGVGGGLVGLSAGAF-GGALLAFALVALLARAAGGGSATLVLAGIAGSQLFNALTSFFIARsASAEQARG 189
Cdd:COG0609  76 AALGAVLAIVLGGGLSALGLPLAAFlGALLAALLVYLLARRGGGLSPLRLVLAGVAVSALFSALTSLLLLL-ADPEQLRS 154

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77389811 190 IMFWLLGNLSGVRWPDVTLALPAALAGLLLCLWHIRAMDAFSFGTQSAKALGVPVRRVQAVLIGITTLMTAVMVSLVGSI 269
Cdd:COG0609 155 IVFWLMGSLAGASWDDVLLLLPVLLIGLLLALLLARALNALALGDETARSLGVNVERLRLLLLLLAALLTGAAVAVAGPI 234

                       250       260       270       280       290       300       310
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 77389811 270 GFVGLVVPHAVRLVAGPRHGALVPWAALAGAIFLIAADVVSRVLIAGQVVPIGVVTALVGAPGFALILIRNR 341
Cdd:COG0609 235 GFVGLVVPHIARLLVGPDHRRLLPASALLGALLLLLADTLARTILAPAELPVGIVTALIGAPFFLYLLRRRR 306
FecCD pfam01032
FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport ...
 59-339 6.69e-59

FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.


Pssm-ID: 426003  Cd Length: 311  Bit Score: 192.36  E-value: 6.69e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77389811    59 DPIEAGIVWNYRLPRTLVAAACGAGLALSGVVLQSLVRNALADPYLLGVSAGASTGAVAVAILGVGGGLVGLSAGAF-GG 137
Cdd:pfam01032  31 DSLAALIVLDLRLPRVLAALLVGAALAVSGALLQTVTRNPLADPSILGISSGAALGAVLAILLGGSLSLFALPLAAFiGA 110

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77389811   138 ALLAFALVALLARAAGGGSATLVLAGIAGSQLFNALTSFFIARsASAEQARGIMFWLLGNLSGVRWPDVTLALPAALAGL 217
Cdd:pfam01032 111 LLAALLVYFLSRGRGGASPLRLILAGIAVSALLSALTSLLLLL-LNPEALQSILFWLMGSLSGANWSDVLILLPLLLIGL 189

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77389811   218 LLCLWHIRAMDAFSFGTQSAKALGVPVRRVQAVLIGITTLMTAVMVSLVGSIGFVGLVVPHAVRLVAGPRHGALVPWAAL 297
Cdd:pfam01032 190 ILLLLLARKLNLLSLGDDTAKSLGVNVNRVRLLLLLLASLLTAASVAVVGPIGFVGLIVPHIARLLVGANHRRLLPLSAL 269

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 77389811   298 AGAIFLIAADVVSRVLIAGQVVPIGVVTALVGAPGFALILIR 339
Cdd:pfam01032 270 LGALLLLLADILARTILSPYELPVGIVTALIGAPFFIYLLLR 311
F420-0_ABCperm TIGR03869
proposed F420-0 ABC transporter, permease protein; his small clade of ABC-type transporter ...
 42-342 7.37e-59

proposed F420-0 ABC transporter, permease protein; his small clade of ABC-type transporter permease protein components is found as a three gene cassette along with a periplasmic substrate-binding protein (TIGR03868) and an ATPase (TIGR03873). The organisms containing this cassette are all Actinobacteria and all contain numerous genes requiring the coenzyme F420. This model was defined based on five such organisms, four of which are lacking all F420 biosynthetic capability save the final side-chain polyglutamate attachment step (via the gene cofE: TIGR01916). In Jonesia denitrificans DSM 20603 and marine actinobacterium PHSC20C1 this cassette is in an apparent operon with the cofE gene and, in PHSC20C1, also with an F420-dependent glucose-6-phosphate dehydrogenase (TIGR03554). Based on these observations we propose that this permease protein is a component of a F420-0 (that is, F420 lacking only the polyglutamate tail) transporter.


Pssm-ID: 163581  Cd Length: 325  Bit Score: 192.76  E-value: 7.37e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77389811    42 TVAATFANRIWGAGLAVDPIEAGIVWNYRLPRTLVAAACGAGLALSGVVLQSLVRNALADPYLLGVSAGASTGAVAVAIL 121
Cdd:TIGR03869  25 SVAAHLGRGEGFPGVALSRLQDAIVWDLRLPRVLTAAAVGAGLAIAGAVMQSLTRNPLADPYLLGLSSGASLGAVAVLVL 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77389811   122 GVGGGLvglSAGAFGGALLAFALVALLARAAGGGSAT-LVLAGIAGSQLFNALTSFFIARSASAEQARGIMFWLLGNLSG 200
Cdd:TIGR03869 105 GVAVLL---PVAAFAGALLALAATLGLARTLGTLTPTrTILAGLAVSQLCAAVTSFVIFWSATGDSYREILSWLMGSLAG 181

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77389811   201 VRWPDVTLALPAALAGLLLCLWHIRAMDAFSFGTQSAKALGVPVRRVQAVLIGITTLMTAVMVSLVGSIGFVGLVVPHAV 280
Cdd:TIGR03869 182 ATWGSVAIAGGALLVVGLVLLASGRVLDAFAFGDSSAAALGVDVERTRWLLLTLVALLTGALVSVSGAIGFVGLILPHAV 261

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 77389811   281 RLVAGPRHGALVPWAALAGAIFLIAADVVSRVLIAGQVVPIGVVTALVGAPGFALILIRNRR 342
Cdd:TIGR03869 262 RLLTGPRHRLLLPVSALAGAVFLVWADTLARTVFAPRELPVGIITALIGAPVFAVLLYRSRS 323
PRK03784 PRK03784
vtamin B12-transporter permease; Provisional
 65-343 2.04e-45

vtamin B12-transporter permease; Provisional


Pssm-ID: 235159  Cd Length: 331  Bit Score: 157.81  E-value: 2.04e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77389811   65 IVWNYRLPRTLVAAACGAGLALSGVVLQSLVRNALADPYLLGVSAGASTGAV-AVAILGVGGGLVGLSAGAFGGALLAFA 143
Cdd:PRK03784  53 FVWQLRLPRTLAVLLVGAALAVSGAVMQALFENPLAEPGLLGVSNGAGVALVaAVLLGQGLLPPWALSLCAIAGALLITL 132

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77389811  144 LVALLARAAGGGSATLVLAGIAGSQLFNALTSFFIARSASAEqARGIMFWLLGNLSGVRWPDVTLALPAALAGLLLClWH 223
Cdd:PRK03784 133 ILLRFARRHRLSTSRLLLAGVALGIICSALMTWAVYFSTSLD-LRQLMYWMMGGFGGVDWRQSWLMLALLPVLIWLC-CQ 210

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77389811  224 IRAMDAFSFGTQSAKALGVPVRRVQAVLIGITTLMTAVMVSLVGSIGFVGLVVPHAVRLVAGPRHGALVPWAALAGAIFL 303
Cdd:PRK03784 211 GRPLNMLALGEISARQLGLPLWFWRNLLVLATGWLVGVSVALAGAIGFIGLVIPHILRLCGLTDHRVLLPGCALAGASLL 290

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 77389811  304 IAADVVSRVLIAGQVVPIGVVTALVGAPGFALILIRNRRR 343
Cdd:PRK03784 291 LLADIVARLALASAELPIGVVTATLGAPVFIWLLLRSHRA 330
TM_ABC_iron-siderophores_like cd06550
Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 87-337 5.47e-37

Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The TMs are bundles of alpha helices that transverse the cytoplasmic membrane multiple times. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Each TM has a prominent cytoplasmic loop which contacts an ABC and represents a conserved motif. The two TMs form either a homodimer (e.g. in the case of the BtuC subunits of the Escherichia coli BtuCD vitamin B12 transporter), a heterodimer (e.g. the TroC and TroD subunits of the Treponema pallidum general transition metal transporter, TroBCD), or a pseudo-heterodimer (e.g. the FhuB protein of the E. coli ferrichrome transporter, FhuBC). FhuB contains two tandem TMs which associate to form the pseudo-heterodimer. Both FhuB TMs are found in this hierarchy.


Pssm-ID: 119348 [Multi-domain]  Cd Length: 261  Bit Score: 133.84  E-value: 5.47e-37
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77389811  87 SGVVLQSLVRNALADPYLLGVSAGASTGAVAVAILGVGGGLVGLSAGAFGGALLAFALVALLARAAGGGSATLVLAGIAG 166
Cdd:cd06550  14 SGAILQSLTRNRLASPSILGISHGALLGVVLALLLGIGLSNYALGAFAFAGALAIALLVLLLASRGGLSPSKLILIGIVL 93

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77389811 167 SQLFNALTSFFIARSASAEQArgIMFWLLGNLSGVRWPDVTLALPAALAGLLLCLWHIRAMDAFSFGTQSAKALGVPVRR 246
Cdd:cd06550  94 SAFFSAGVILISLLSDDSLQD--LNIWLFGSILGVTWEDLLILLIILLLVLLLLLLLSRKLNLLTFDEDLAKSLGINVNL 171

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77389811 247 VQAVLIGITTLMTAVMVSLVGSIGFVGLVVPHAVRLVAGPRHGALVPWAALAGAIFLIAADVVSRVLIAGQvVPIGVVTA 326
Cdd:cd06550 172 LRLLLLLLVALLVVAAVALVGVILFVGLIAPHLARRLFGRSHRYLLPLSALLGAILLLLGDLLSRTLLPSE-LPVGPVTA 250

                       250
                ....*....|.
gi 77389811 327 LVGAPGFALIL 337
Cdd:cd06550 251 LLGAPYFLYLL 261
 
Name Accession Description Interval E-value
FepD COG0609
ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and ...
 31-341 8.03e-79

ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440374  Cd Length: 306  Bit Score: 243.05  E-value: 8.03e-79
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77389811  31 VVIGETPLPLPTVAATFAnriwgaGLAVDPIEAGIVWNYRLPRTLVAAACGAGLALSGVVLQSLVRNALADPYLLGVSAG 110
Cdd:COG0609   2 LSLGAVPISLSDVLRALL------GPDGDPTADLIVWDLRLPRVLLALLVGAALAVAGALMQGLTRNPLADPGILGVSSG 75

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77389811 111 ASTGAVAVAILGVGGGLVGLSAGAF-GGALLAFALVALLARAAGGGSATLVLAGIAGSQLFNALTSFFIARsASAEQARG 189
Cdd:COG0609  76 AALGAVLAIVLGGGLSALGLPLAAFlGALLAALLVYLLARRGGGLSPLRLVLAGVAVSALFSALTSLLLLL-ADPEQLRS 154

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77389811 190 IMFWLLGNLSGVRWPDVTLALPAALAGLLLCLWHIRAMDAFSFGTQSAKALGVPVRRVQAVLIGITTLMTAVMVSLVGSI 269
Cdd:COG0609 155 IVFWLMGSLAGASWDDVLLLLPVLLIGLLLALLLARALNALALGDETARSLGVNVERLRLLLLLLAALLTGAAVAVAGPI 234

                       250       260       270       280       290       300       310
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 77389811 270 GFVGLVVPHAVRLVAGPRHGALVPWAALAGAIFLIAADVVSRVLIAGQVVPIGVVTALVGAPGFALILIRNR 341
Cdd:COG0609 235 GFVGLVVPHIARLLVGPDHRRLLPASALLGALLLLLADTLARTILAPAELPVGIVTALIGAPFFLYLLRRRR 306
FecCD pfam01032
FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport ...
 59-339 6.69e-59

FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.


Pssm-ID: 426003  Cd Length: 311  Bit Score: 192.36  E-value: 6.69e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77389811    59 DPIEAGIVWNYRLPRTLVAAACGAGLALSGVVLQSLVRNALADPYLLGVSAGASTGAVAVAILGVGGGLVGLSAGAF-GG 137
Cdd:pfam01032  31 DSLAALIVLDLRLPRVLAALLVGAALAVSGALLQTVTRNPLADPSILGISSGAALGAVLAILLGGSLSLFALPLAAFiGA 110

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77389811   138 ALLAFALVALLARAAGGGSATLVLAGIAGSQLFNALTSFFIARsASAEQARGIMFWLLGNLSGVRWPDVTLALPAALAGL 217
Cdd:pfam01032 111 LLAALLVYFLSRGRGGASPLRLILAGIAVSALLSALTSLLLLL-LNPEALQSILFWLMGSLSGANWSDVLILLPLLLIGL 189

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77389811   218 LLCLWHIRAMDAFSFGTQSAKALGVPVRRVQAVLIGITTLMTAVMVSLVGSIGFVGLVVPHAVRLVAGPRHGALVPWAAL 297
Cdd:pfam01032 190 ILLLLLARKLNLLSLGDDTAKSLGVNVNRVRLLLLLLASLLTAASVAVVGPIGFVGLIVPHIARLLVGANHRRLLPLSAL 269

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 77389811   298 AGAIFLIAADVVSRVLIAGQVVPIGVVTALVGAPGFALILIR 339
Cdd:pfam01032 270 LGALLLLLADILARTILSPYELPVGIVTALIGAPFFIYLLLR 311
F420-0_ABCperm TIGR03869
proposed F420-0 ABC transporter, permease protein; his small clade of ABC-type transporter ...
 42-342 7.37e-59

proposed F420-0 ABC transporter, permease protein; his small clade of ABC-type transporter permease protein components is found as a three gene cassette along with a periplasmic substrate-binding protein (TIGR03868) and an ATPase (TIGR03873). The organisms containing this cassette are all Actinobacteria and all contain numerous genes requiring the coenzyme F420. This model was defined based on five such organisms, four of which are lacking all F420 biosynthetic capability save the final side-chain polyglutamate attachment step (via the gene cofE: TIGR01916). In Jonesia denitrificans DSM 20603 and marine actinobacterium PHSC20C1 this cassette is in an apparent operon with the cofE gene and, in PHSC20C1, also with an F420-dependent glucose-6-phosphate dehydrogenase (TIGR03554). Based on these observations we propose that this permease protein is a component of a F420-0 (that is, F420 lacking only the polyglutamate tail) transporter.


Pssm-ID: 163581  Cd Length: 325  Bit Score: 192.76  E-value: 7.37e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77389811    42 TVAATFANRIWGAGLAVDPIEAGIVWNYRLPRTLVAAACGAGLALSGVVLQSLVRNALADPYLLGVSAGASTGAVAVAIL 121
Cdd:TIGR03869  25 SVAAHLGRGEGFPGVALSRLQDAIVWDLRLPRVLTAAAVGAGLAIAGAVMQSLTRNPLADPYLLGLSSGASLGAVAVLVL 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77389811   122 GVGGGLvglSAGAFGGALLAFALVALLARAAGGGSAT-LVLAGIAGSQLFNALTSFFIARSASAEQARGIMFWLLGNLSG 200
Cdd:TIGR03869 105 GVAVLL---PVAAFAGALLALAATLGLARTLGTLTPTrTILAGLAVSQLCAAVTSFVIFWSATGDSYREILSWLMGSLAG 181

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77389811   201 VRWPDVTLALPAALAGLLLCLWHIRAMDAFSFGTQSAKALGVPVRRVQAVLIGITTLMTAVMVSLVGSIGFVGLVVPHAV 280
Cdd:TIGR03869 182 ATWGSVAIAGGALLVVGLVLLASGRVLDAFAFGDSSAAALGVDVERTRWLLLTLVALLTGALVSVSGAIGFVGLILPHAV 261

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 77389811   281 RLVAGPRHGALVPWAALAGAIFLIAADVVSRVLIAGQVVPIGVVTALVGAPGFALILIRNRR 342
Cdd:TIGR03869 262 RLLTGPRHRLLLPVSALAGAVFLVWADTLARTVFAPRELPVGIITALIGAPVFAVLLYRSRS 323
BtuC COG4139
ABC-type cobalamin transport system, permease component BtuC [Coenzyme transport and ...
 65-342 5.75e-46

ABC-type cobalamin transport system, permease component BtuC [Coenzyme transport and metabolism];


Pssm-ID: 443314  Cd Length: 327  Bit Score: 159.25  E-value: 5.75e-46
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77389811  65 IVWNYRLPRTLVAAACGAGLALSGVVLQSLVRNALADPYLLGVSAGASTGAV-AVAILGVGGGLVGLSAGAFGGALLAFA 143
Cdd:COG4139  50 FVWQLRLPRTLAAVLVGASLAVSGAVMQALFENPLAEPGLLGISNGAGVGLVlVVLLGGGLLPPWLLSLAAIAGALLVTL 129

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77389811 144 LVALLARAAGGGSAtLVLAGIAGSQLFNALTSFFIARSaSAEQARGIMFWLLGNLSGVRWPDVTLALPAALAGLLLClWH 223
Cdd:COG4139 130 LLLAFARRRLSNAR-LLLIGVALGIICSAIMTWAVYFS-SSLDLRQLMYWMMGSFGGVDWRQLWLLLALLPVLLWLC-LQ 206

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77389811 224 IRAMDAFSFGTQSAKALGVPVRRVQAVLIGITTLMTAVMVSLVGSIGFVGLVVPHAVRLVAGPRHGALVPWAALAGAIFL 303
Cdd:COG4139 207 GKPLNLLLLGENQARQLGLSVHRWRNLLVLATGLLVGVSVALAGPIGFVGLVVPHLLRLLGTTDHRFLLPACALAGAALL 286

                       250       260       270
                ....*....|....*....|....*....|....*....
gi 77389811 304 IAADVVSRVLIAGQVVPIGVVTALVGAPGFALILIRNRR 342
Cdd:COG4139 287 LLADIIARLALSSAELPIGVVTATLGAPVFIWLLLRRRK 325
PRK03784 PRK03784
vtamin B12-transporter permease; Provisional
 65-343 2.04e-45

vtamin B12-transporter permease; Provisional


Pssm-ID: 235159  Cd Length: 331  Bit Score: 157.81  E-value: 2.04e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77389811   65 IVWNYRLPRTLVAAACGAGLALSGVVLQSLVRNALADPYLLGVSAGASTGAV-AVAILGVGGGLVGLSAGAFGGALLAFA 143
Cdd:PRK03784  53 FVWQLRLPRTLAVLLVGAALAVSGAVMQALFENPLAEPGLLGVSNGAGVALVaAVLLGQGLLPPWALSLCAIAGALLITL 132

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77389811  144 LVALLARAAGGGSATLVLAGIAGSQLFNALTSFFIARSASAEqARGIMFWLLGNLSGVRWPDVTLALPAALAGLLLClWH 223
Cdd:PRK03784 133 ILLRFARRHRLSTSRLLLAGVALGIICSALMTWAVYFSTSLD-LRQLMYWMMGGFGGVDWRQSWLMLALLPVLIWLC-CQ 210

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77389811  224 IRAMDAFSFGTQSAKALGVPVRRVQAVLIGITTLMTAVMVSLVGSIGFVGLVVPHAVRLVAGPRHGALVPWAALAGAIFL 303
Cdd:PRK03784 211 GRPLNMLALGEISARQLGLPLWFWRNLLVLATGWLVGVSVALAGAIGFIGLVIPHILRLCGLTDHRVLLPGCALAGASLL 290

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 77389811  304 IAADVVSRVLIAGQVVPIGVVTALVGAPGFALILIRNRRR 343
Cdd:PRK03784 291 LLADIVARLALASAELPIGVVTATLGAPVFIWLLLRSHRA 330
PRK10577 PRK10577
Fe(3+)-hydroxamate ABC transporter permease FhuB;
38-343 1.17e-44

Fe(3+)-hydroxamate ABC transporter permease FhuB;


Pssm-ID: 236720 [Multi-domain]  Cd Length: 668  Bit Score: 161.93  E-value: 1.17e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77389811   38 LPLPTVAATFANRIWGAGLAVDPIEAGIVWNYRLPRTLVAAACGAGLALSGVVLQSLVRNALADPYLLGVSAGASTGAVA 117
Cdd:PRK10577 365 LLLALVVALSFGRDAHGWNWLSGQLLDALLPLRLPRLLAALLAGAMLAVAGTLLQRLTRNPLASPEVLGISSGAGLGVVL 444

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77389811  118 VAILGVGGGLVGLSAGAFGGALLAFALVALLARAAGGGSATLVLAGIAGSQLFNALTSFFIARSASaeQARGIMFWLLGN 197
Cdd:PRK10577 445 ALFLVPGAGFGWLLAAALLGALAALALILLLARRGGFAPERLLLTGIALSALFTALIQLLLASGDP--RAAQLLTWLSGS 522

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77389811  198 LSGVRWPDVTLALPAALAGLLLCLWHIRAMDAFSFGTQSAKALGVPVRRVQAVLIGITTLMTAVMVSLVGSIGFVGLVVP 277
Cdd:PRK10577 523 TYGVTWAQALPLLIVAVLLLALALLLRRWLDLLPLGDDTARALGLPVTRARLALLLLAALLTAAATATVGPLSFVGLMAP 602

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 77389811  278 HAVRLVAGPRHGALVPWAALAGAIFLIAADVVSRVLIAGQVVPIGVVTALVGAPGFALILIRNRRR 343
Cdd:PRK10577 603 HLARMLGGRRARPQLVLAALLGALLMVLADWLGRTLLFPYQIPAGLLAALIGAPYFLWLLRRSRRR 668
btuC PRK09535
cobalamin ABC transporter permease BtuC;
31-341 3.16e-44

cobalamin ABC transporter permease BtuC;


Pssm-ID: 236553  Cd Length: 366  Bit Score: 155.68  E-value: 3.16e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77389811   31 VVIGETPLPLPTVAATFAnriwgAGLAVDPIEAGIVWNYRLPRTLVAAACGAGLALSGVVLQSLVRNALADPYLLGVSAG 110
Cdd:PRK09535  61 VLSVGLSLPAPDLEYASP-----FSFAVPETAQTIVLQIRLPRILLAATVGFALAAAGTVMQGFFRNPMADPSIIGVSSG 135

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77389811  111 ASTGAVAvAILGVGGGLVGLSAGAFGGALLAFALVALLARAAG-GGSATLVLAGIAGSQLFNALTSFFIARSAsaEQARG 189
Cdd:PRK09535 136 AAVGAVA-AIVLPLAVPFGLQAAAFAGALVAAFGVYAIATENGrTPVATLLLAGVAVQTFLGAVISYLLLHSG--ESLRR 212

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77389811  190 IMFWLLGNLSGVRWPDVTLALPAALAGLLLCLWHIRAMDAFSFGTQSAKALGVPVRRVQAVLIGITTLMTAVMVSLVGSI 269
Cdd:PRK09535 213 AVYWLMGHLHGSTWSDVEVALPVVVVGFVVLLAYARDLNVLLLGEEDAHTLGIEVERTKRLLLALASVVTAAAVAVAGVI 292

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 77389811  270 GFVGLVVPHAVRLVAGPRHGALVPWAALAGAIFLIAADVVSRVliAGQVVPIGVVTALVGAPgFALILIRNR 341
Cdd:PRK09535 293 GFVGLIVPHVMRLLVGPDHRILLPTSALAGASFLVATDTVARS--GPAEVPVGIVTAALGAP-FFLYLLRTR 361
PRK10577 PRK10577
Fe(3+)-hydroxamate ABC transporter permease FhuB;
54-343 2.20e-37

Fe(3+)-hydroxamate ABC transporter permease FhuB;


Pssm-ID: 236720 [Multi-domain]  Cd Length: 668  Bit Score: 141.90  E-value: 2.20e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77389811   54 AGLAVDPIEAGIVWNYRLPRTLVAAACGAGLALSGVVLQSLVRNALADPYLLGVSAGASTGAVAVAILGVGGGLVGLSAG 133
Cdd:PRK10577  46 WGPDADDLEQLLLHYSRLPRLAIALLVGAALGLAGALLQQVLRNPLASPTTLGVAAGAQLALVLATLFAPALLALASQLA 125

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77389811  134 AFGGALLAFALVALLARAAGGGSATLVLAGIAGSQLFNALTSFFIArsASAEQARGIMFWLLGNLSGVRWPDVTLALPAA 213
Cdd:PRK10577 126 AFAGGLLAAALVFALAGGKRLSPLRLVLAGMVVSLYLGALTTLLLL--FNEQYLQGLFLWGAGSLAQNDWSGVQRLLPRL 203

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77389811  214 LAGLLLCLWHIRAMDAFSFGTQSAKALGVPVRRVQAVLIGITTLMTAVMVSLVGSIGFVGLVVPHAVRLVAGPRHGALVP 293
Cdd:PRK10577 204 LVGLLLLLLLARPLTLLGLGDDVARSLGLAVSLTRLAALALAVLLSAAVVSAVGPIGFIGLAAPNLARLLGARRLRARLP 283

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|..
gi 77389811  294 WAALAGAIFLIAADVVSRVL--IAGQVVPIGVVTALVGAPgFALILIRNRRR 343
Cdd:PRK10577 284 LSPLIGALLLLLTDQLVRLLagVGGELLPTGAVTALIGAP-LLLWLLPRLRS 334
TM_ABC_iron-siderophores_like cd06550
Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 87-337 5.47e-37

Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The TMs are bundles of alpha helices that transverse the cytoplasmic membrane multiple times. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Each TM has a prominent cytoplasmic loop which contacts an ABC and represents a conserved motif. The two TMs form either a homodimer (e.g. in the case of the BtuC subunits of the Escherichia coli BtuCD vitamin B12 transporter), a heterodimer (e.g. the TroC and TroD subunits of the Treponema pallidum general transition metal transporter, TroBCD), or a pseudo-heterodimer (e.g. the FhuB protein of the E. coli ferrichrome transporter, FhuBC). FhuB contains two tandem TMs which associate to form the pseudo-heterodimer. Both FhuB TMs are found in this hierarchy.


Pssm-ID: 119348 [Multi-domain]  Cd Length: 261  Bit Score: 133.84  E-value: 5.47e-37
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77389811  87 SGVVLQSLVRNALADPYLLGVSAGASTGAVAVAILGVGGGLVGLSAGAFGGALLAFALVALLARAAGGGSATLVLAGIAG 166
Cdd:cd06550  14 SGAILQSLTRNRLASPSILGISHGALLGVVLALLLGIGLSNYALGAFAFAGALAIALLVLLLASRGGLSPSKLILIGIVL 93

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77389811 167 SQLFNALTSFFIARSASAEQArgIMFWLLGNLSGVRWPDVTLALPAALAGLLLCLWHIRAMDAFSFGTQSAKALGVPVRR 246
Cdd:cd06550  94 SAFFSAGVILISLLSDDSLQD--LNIWLFGSILGVTWEDLLILLIILLLVLLLLLLLSRKLNLLTFDEDLAKSLGINVNL 171

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77389811 247 VQAVLIGITTLMTAVMVSLVGSIGFVGLVVPHAVRLVAGPRHGALVPWAALAGAIFLIAADVVSRVLIAGQvVPIGVVTA 326
Cdd:cd06550 172 LRLLLLLLVALLVVAAVALVGVILFVGLIAPHLARRLFGRSHRYLLPLSALLGAILLLLGDLLSRTLLPSE-LPVGPVTA 250

                       250
                ....*....|.
gi 77389811 327 LVGAPGFALIL 337
Cdd:cd06550 251 LLGAPYFLYLL 261
fecD PRK09777
Fe(3+) dicitrate ABC transporter permease subunit FecD;
69-341 3.39e-33

Fe(3+) dicitrate ABC transporter permease subunit FecD;


Pssm-ID: 182071  Cd Length: 318  Bit Score: 125.16  E-value: 3.39e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77389811   69 YRLPRTLVAAACGAGLALSGVVLQSLVRNALADPYLLGVSAGASTGAVAVAILGVGGGLVGLSAGAFGGALLAFALVALL 148
Cdd:PRK09777  50 YRLPRLLLALFVGAALAVSGVLVQGIVRNPLASPDILGVNHAASLASVGALLLFPSLPVMWLPLLAFIGGMAGLILLKML 129

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77389811  149 AraagGGSATLVLA--GIAGSQLFNALTSFFI-ARSASAEQArgiMFWLLGNLSGVRWPDVTLALPAALAGLLLCLWHIR 225
Cdd:PRK09777 130 A----GTHQPMKLAltGVALSALWASLTDYLMlSRPQDINNA---LLWLTGSLWGRDWSFVKVALPWLILLLPLSLSFCR 202

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77389811  226 AMDAFSFGTQSAKALGVPVRRVQAVLIGITTLMTAVMVSLVGSIGFVGLVVPHAVRLVAGPRHGALVPWAALAGAIFLIA 305
Cdd:PRK09777 203 DLDLLALGDARATTLGVSVPHTQFWALLLAVALTATGVAACGPISFIGLVVPHLMRSLVGGRHRRLLPVSALTGALLLLL 282

                        250       260       270
                 ....*....|....*....|....*....|....*.
gi 77389811  306 ADVVSRVLIAGQVVPIGVVTALVGAPGFALILIRNR 341
Cdd:PRK09777 283 ADLLARIIHPPLELPAGVLTAIIGAPWFFWLLVRMR 318
fecC PRK11228
iron-dicitrate ABC transporter permease FecC;
58-342 2.81e-28

iron-dicitrate ABC transporter permease FecC;


Pssm-ID: 183042  Cd Length: 323  Bit Score: 112.10  E-value: 2.81e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77389811   58 VDPIEAGIVWNYRLPRTLVAAACGAGLALSGVVLQSLVRNALADPYLLGVSAGASTG---AVAVAILGVGGGLVGLSAGA 134
Cdd:PRK11228  39 TPTLPEALVQNLRLPRSLVAVLIGASLALAGALLQTLTHNPLASPSLLGINSGAALAmalTSALSPTPFAGYSLAFIAAC 118

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77389811  135 FGGALLAFALVALLARAAGGGSATLVLAGIAGSQLFNALTSFFIArsASAEQARGIMFWLLGNLSGVRWPDVTLALPAAL 214
Cdd:PRK11228 119 GGGLSWLLVMTAGGGWRHTHDRNRLILAGIALSALCMALTRITLL--LAEDHAYGIFYWLAGGVSHARWQEVWQLLPFVV 196

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77389811  215 AGLLLCLWHIRAMDAFSFGTQSAKALGVPVRRVQAVLIGITTLMTAVMVSLVGSIGFVGLVVPHAVRLVAGPRHGALVPW 294
Cdd:PRK11228 197 TAVPVVLLLANQLNLLNLSDSSAHTLGVNLTRLRLVVNMLVLLLVGACVSVAGPVAFIGLLVPHLARFWIGYDQRNVLPM 276

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*...
gi 77389811  295 AALAGAIFLIAADVVSRVLIAGQVVPIGVVTALVGAPGFaLILIRNRR 342
Cdd:PRK11228 277 SMLLGATLMLLADLLARALAFPGELPAGAVLALIGAPCF-VWLARRRG 323
PRK10441 PRK10441
Fe(3+)-siderophore ABC transporter permease;
31-343 3.47e-25

Fe(3+)-siderophore ABC transporter permease;


Pssm-ID: 182464  Cd Length: 335  Bit Score: 103.63  E-value: 3.47e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77389811   31 VVIGETPLPLPTVAATFANRIWGAglavdpiEAGIVWNYRLPRTLVAAACGAGLALSGVVLQSLVRNALADPYLLGVSAG 110
Cdd:PRK10441  28 LLIGAKSLPASVVLEALSGTCQSA-------DCTIVLDARLPRTLAGLLAGGALGLAGALMQTLTRNPLADPGLLGVNAG 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77389811  111 ASTGAVAVAILGVGGGLVGLSAGAFGGALLAFALVALLARAAGG--GSATLVLAGIAGSQLFNALTSFFIARSASA-EQA 187
Cdd:PRK10441 101 ASFAIVLGAALFGYSSAQEQLAMAFAGALVASLIVAFTGSQGGGqlSPVRLTLAGVALAAVLEGLTSGIALLNPDVyDQL 180

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77389811  188 RgimFWLLGNLSGVRWPDVTLALPAALAGLLLCLWHIRAMDAFSFGTQSAKALGVPVRRVQAVLIGITTLMTAVMVSLVG 267
Cdd:PRK10441 181 R---FWQAGSLDIRNLHTLKVVLIPVLIAGATALLLSRALNSLSLGSDTATALGSRVARTQLIGLLAITVLCGSATAVVG 257

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 77389811  268 SIGFVGLVVPHAVRLVAGPRHGALVPWAALAGAIFLIAADVVSRVLIAGQvVPIGVVTALVGAPgfALILIRNRRR 343
Cdd:PRK10441 258 PIAFIGLMMPHMARWLVGADHRWSLPVTLLATPALLLFADIIGRLLVPGE-LRVSVVSAFIGAP--VLIFLVRRKT 330
PRK10440 PRK10440
iron-enterobactin ABC transporter permease;
65-343 7.53e-25

iron-enterobactin ABC transporter permease;


Pssm-ID: 182463  Cd Length: 330  Bit Score: 102.87  E-value: 7.53e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77389811   65 IVWNYRLPRTLVAAACGAGLALSGVVLQSLVRNALADPYLLGVSAGASTGAVaVAILGVGGGLVGLSAGAFGGALLAFAL 144
Cdd:PRK10440  54 VVTEWRLPRVLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTGAWSGVL-VAMVLFGQDLTAIALAAMAGGIVTSLL 132

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77389811  145 VALLARAAGGGSATLVLAGIAGSQLFNALTSFFIArSASAEQARGIMFWLLGNLSGVRWPDVTLALPAALAGLLLCLWHI 224
Cdd:PRK10440 133 VWLLAWRNGIDTFRLIIIGIGVRAMLVAFNTWLLL-KASLETALTAGLWNAGSLNGLTWAKTSPSAPIIILMLIAAALLV 211

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77389811  225 RAMDAFSFGTQSAKALGVPVRRVQAVLIGITTLMTAVMVSLVGSIGFVGLVVPHAVRLVAGPRHGALVPwAALAGAIFLI 304
Cdd:PRK10440 212 RRMRLLEMGDDTACALGVSVERSRLLLMLVAVVLTAAATALAGPISFIALVAPHIARRLSGTARWGLTQ-AALCGALLLL 290

                        250       260       270
                 ....*....|....*....|....*....|....*....
gi 77389811  305 AADVVSRVLIAGQVVPIGVVTALVGAPGFALILIRNRRR 343
Cdd:PRK10440 291 AADLCAQQLFMPYQLPVGVVTVSLGGIYLIVLLIQESRK 329
ZnuB COG1108
ABC-type Mn2+/Zn2+ transport system, permease component [Inorganic ion transport and ...
 181-343 1.38e-03

ABC-type Mn2+/Zn2+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440725  Cd Length: 260  Bit Score: 39.64  E-value: 1.38e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77389811 181 SASAEQARGIMFWLLGNLSGVRWPDVTLALPAALAGLLLCLWHIRAMDAFSFGTQSAKALGVPVRRVQAVLIGITTLMTA 260
Cdd:COG1108 101 SLVPGSAVDLMSYLFGSILAVSRSDLLLLAVLAAVVLLLLLLFYRELLLVSFDPELARASGLPVRLLHLLLLVLLALTVV 180

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77389811 261 VMVSLVGSIGFVGLVV--PHAVRLVAGpRHGALVPWAALAGAIFLIAADVVSRVLiagqVVPIGVVTALVGAPGFALILI 338
Cdd:COG1108 181 AALQAVGALLVSALLIipAATARLLTR-SLRRMLLLAVLIGVLSSVLGLYLSYYL----DLPTGPTIVLVAGLLFLLSLL 255


                ....*
gi 77389811 339 RNRRR 343
Cdd:COG1108 256 FSPRR 260
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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