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Conserved domains on  [gi|83316501|gb|ABC02427|]
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PapR [Bacillus mycoides]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Bacillus_PapR super family cl05495
Bacillus PapR protein; This family consists of the Bacillus species specific PapR protein. The ...
 1-48 2.31e-21

Bacillus PapR protein; This family consists of the Bacillus species specific PapR protein. The papR gene belongs to the PlcR regulon and is located 70 bp downstream from plcR. It encodes a 48-amino-acid peptide. Disruption of the papR gene abolishes expression of the PlcR regulon, resulting in a large decrease in haemolysis and virulence in insect larvae. A processed form of PapR activates the PlcR regulon by allowing PlcR to bind to its DNA target. This activating mechanism is strain specific.


The actual alignment was detected with superfamily member pfam05968:

Pssm-ID: 428697  Cd Length: 48  Bit Score: 77.01  E-value: 2.31e-21
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 83316501    1 MKKLLIGSLLTLAMAWGISLTDTALEKSQVISHNDQEVQLASDLPFEH 48
Cdd:pfam05968  1 MKKLLIGSLLTLAMAWGISLGDTALEKNHIISHNDQEVQLAKDLPFEY 48
 
Name Accession Description Interval E-value
Bacillus_PapR pfam05968
Bacillus PapR protein; This family consists of the Bacillus species specific PapR protein. The ...
 1-48 2.31e-21

Bacillus PapR protein; This family consists of the Bacillus species specific PapR protein. The papR gene belongs to the PlcR regulon and is located 70 bp downstream from plcR. It encodes a 48-amino-acid peptide. Disruption of the papR gene abolishes expression of the PlcR regulon, resulting in a large decrease in haemolysis and virulence in insect larvae. A processed form of PapR activates the PlcR regulon by allowing PlcR to bind to its DNA target. This activating mechanism is strain specific.


Pssm-ID: 428697  Cd Length: 48  Bit Score: 77.01  E-value: 2.31e-21
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 83316501    1 MKKLLIGSLLTLAMAWGISLTDTALEKSQVISHNDQEVQLASDLPFEH 48
Cdd:pfam05968  1 MKKLLIGSLLTLAMAWGISLGDTALEKNHIISHNDQEVQLAKDLPFEY 48
 
Name Accession Description Interval E-value
Bacillus_PapR pfam05968
Bacillus PapR protein; This family consists of the Bacillus species specific PapR protein. The ...
 1-48 2.31e-21

Bacillus PapR protein; This family consists of the Bacillus species specific PapR protein. The papR gene belongs to the PlcR regulon and is located 70 bp downstream from plcR. It encodes a 48-amino-acid peptide. Disruption of the papR gene abolishes expression of the PlcR regulon, resulting in a large decrease in haemolysis and virulence in insect larvae. A processed form of PapR activates the PlcR regulon by allowing PlcR to bind to its DNA target. This activating mechanism is strain specific.


Pssm-ID: 428697  Cd Length: 48  Bit Score: 77.01  E-value: 2.31e-21
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 83316501    1 MKKLLIGSLLTLAMAWGISLTDTALEKSQVISHNDQEVQLASDLPFEH 48
Cdd:pfam05968  1 MKKLLIGSLLTLAMAWGISLGDTALEKNHIISHNDQEVQLAKDLPFEY 48
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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