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Conserved domains on  [gi|256041152|gb|ACU64696|]
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ABC transporter related [Chitinophaga pinensis DSM 2588]

Protein Classification

ABC transporter ATP-binding protein( domain architecture ID 11467920)

ABC transporter ATP-binding protein is the ATPase catalytic subunit of an ABC transporter complex and is responsible for coupling the energy of ATP hydrolysis to the import of specific solutes; similar to alkaliphilic Bacillus firmus NatA that is involved in Na(+) extrusion

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
YhaQ COG4152
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 4-299 5.22e-173

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


:

Pssm-ID: 443322 [Multi-domain]  Cd Length: 298  Bit Score: 481.15  E-value: 5.22e-173
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPQtDIHAIGYMPEER 83
Cdd:COG4152    2 LELKGLTKRFGDKTAVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGEVLWDGEPLDPE-DRRRIGYLPEER 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  84 GLYKKMKVGEQALYLAQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEPFSGL 163
Cdd:COG4152   81 GLYPKMKVGEQLVYLARLKGLSKAEAKRRADEWLERLGLGDRANKKVEELSKGNQQKVQLIAALLHDPELLILDEPFSGL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 164 DPINANLIKQEIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQIKQDFKQHLFRIGFGVMPNFAQvAT 243
Cdd:COG4152  161 DPVNVELLKDVIRELAAKGTTVIFSSHQMELVEELCDRIVIINKGRKVLSGSVDEIRRQFGRNTLRLEADGDAGWLR-AL 239

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 256041152 244 HHFSIIKQEPLAYTVKLTEGSTNNDILAHFIRHnVPITSFQEILPSINEVFIQQVT 299
Cdd:COG4152  240 PGVTVVEEDGDGAELKLEDGADAQELLRALLAR-GPVREFEEVRPSLNEIFIEVVG 294
 
Name Accession Description Interval E-value
YhaQ COG4152
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 4-299 5.22e-173

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443322 [Multi-domain]  Cd Length: 298  Bit Score: 481.15  E-value: 5.22e-173
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPQtDIHAIGYMPEER 83
Cdd:COG4152    2 LELKGLTKRFGDKTAVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGEVLWDGEPLDPE-DRRRIGYLPEER 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  84 GLYKKMKVGEQALYLAQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEPFSGL 163
Cdd:COG4152   81 GLYPKMKVGEQLVYLARLKGLSKAEAKRRADEWLERLGLGDRANKKVEELSKGNQQKVQLIAALLHDPELLILDEPFSGL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 164 DPINANLIKQEIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQIKQDFKQHLFRIGFGVMPNFAQvAT 243
Cdd:COG4152  161 DPVNVELLKDVIRELAAKGTTVIFSSHQMELVEELCDRIVIINKGRKVLSGSVDEIRRQFGRNTLRLEADGDAGWLR-AL 239

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 256041152 244 HHFSIIKQEPLAYTVKLTEGSTNNDILAHFIRHnVPITSFQEILPSINEVFIQQVT 299
Cdd:COG4152  240 PGVTVVEEDGDGAELKLEDGADAQELLRALLAR-GPVREFEEVRPSLNEIFIEVVG 294
ABC_putative_ATPase cd03269
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ...
 4-214 2.02e-122

ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213236 [Multi-domain]  Cd Length: 210  Bit Score: 349.66  E-value: 2.02e-122
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPQtDIHAIGYMPEER 83
Cdd:cd03269    1 LEVENVTKRFGRVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFDGKPLDIA-ARNRIGYLPEER 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  84 GLYKKMKVGEQALYLAQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEPFSGL 163
Cdd:cd03269   80 GLYPKMKVIDQLVYLAQLKGLKKEEARRRIDEWLERLELSEYANKRVEELSKGNQQKVQFIAAVIHDPELLILDEPFSGL 159

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 256041152 164 DPINANLIKQEIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDG 214
Cdd:cd03269  160 DPVNVELLKDVIRELARAGKTVILSTHQMELVEELCDRVLLLNKGRAVLYG 210
drrA TIGR01188
daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin ...
 11-303 7.47e-63

daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin resistance ABC transporter, ATP binding subunit in bacteria and archaea. This model is restricted in its scope to preferentially recognize the ATP binding subunit associated with effux of the drug, daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins, multidrug resistance protein etc. [Transport and binding proteins, Other]


Pssm-ID: 130256 [Multi-domain]  Cd Length: 302  Bit Score: 201.46  E-value: 7.47e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   11 KHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPF--DPQTDIHAIGYMPEERGLYKK 88
Cdd:TIGR01188   1 KVYGDFKAVDGVNFKVREGEVFGFLGPNGAGKTTTIRMLTTLLRPTSGTARVAGYDVvrEPRKVRRSIGIVPQYASVDED 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   89 MkVGEQALYL-AQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEPFSGLDPIN 167
Cdd:TIGR01188  81 L-TGRENLEMmGRLYGLPKDEAEERAEELLELFELGEAADRPVGTYSGGMRRRLDIAASLIHQPDVLFLDEPTTGLDPRT 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  168 ANLIKQEIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQIKQ----DFKQHLFRIGFGVMPN----FA 239
Cdd:TIGR01188 160 RRAIWDYIRALKEEGVTILLTTHYMEEADKLCDRIAIIDHGRIIAEGTPEELKRrlgkDTLESRPRDIQSLKVEvsmlIA 239

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 256041152  240 QVATHHFSIIKQEPLAYTVKLTEG---STNNDILAHFIRHNVPITSFQEILPSINEVFIqqvtSMTG 303
Cdd:TIGR01188 240 ELGETGLGLLAVTVDSDRIKILVPdgdETVPEIVEAAIRNGIRIRSISTERPSLDDVFL----KLTG 302
PRK13537 PRK13537
nodulation factor ABC transporter ATP-binding protein NodI;
4-214 1.33e-45

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237420 [Multi-domain]  Cd Length: 306  Bit Score: 156.89  E-value: 1.33e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFdPQTDIHA---IGYMP 80
Cdd:PRK13537   8 IDFRNVEKRYGDKLVVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLCGEPV-PSRARHArqrVGVVP 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  81 EERGLYKKMKVGEQALYLAQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEPF 160
Cdd:PRK13537  87 QFDNLDPDFTVRENLLVFGRYFGLSAAAARALVPPLLEFAKLENKADAKVGELSGGMKRRLTLARALVNDPDVLVLDEPT 166

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 256041152 161 SGLDPINANLIKQEIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDG 214
Cdd:PRK13537 167 TGLDPQARHLMWERLRSLLARGKTILLTTHFMEEAERLCDRLCVIEEGRKIAEG 220
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
4-211 5.83e-39

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 146.42  E-value: 5.83e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPQtDIHA---IGYMP 80
Cdd:NF033858 267 IEARGLTMRFGDFTAVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAWLFGQPVDAG-DIATrrrVGYMS 345

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  81 EERGLYKKMKVgEQALYL-AQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEP 159
Cdd:NF033858 346 QAFSLYGELTV-RQNLELhARLFHLPAAEIAARVAEMLERFDLADVADALPDSLPLGIRQRLSLAVAVIHKPELLILDEP 424

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 256041152 160 FSGLDPINANLIKQEIFDLSKN-GTTIIFSTHRMEQVEEiCDRIVLVNQGKKL 211
Cdd:NF033858 425 TSGVDPVARDMFWRLLIELSREdGVTIFISTHFMNEAER-CDRISLMHAGRVL 476
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
 19-161 5.39e-37

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 129.69  E-value: 5.39e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   19 VDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPQTDIHA---IGYMPEERGLYKKMKVGEQA 95
Cdd:pfam00005   1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDDERKSLrkeIGYVFQDPQLFPRLTVRENL 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   96 LYLAQLKGMSERDAKDKIKYWFDKFEINSWYNKKVE----ELSKGMQQKVQFISTIMHSPDLLILDEPFS 161
Cdd:pfam00005  81 RLGLLLKGLSKREKDARAEEALEKLGLGDLADRPVGerpgTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
2-220 3.16e-25

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 103.66  E-value: 3.16e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   2 NLIEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAG--KTTLLRMITGifyPDKGEilfngRPF-------DPQTD 72
Cdd:NF000106  12 NAVEVRGLVKHFGEVKAVDGVDLDVREGTVLGVLGP*GAA**RGALPAHV*G---PDAGR-----RPWrf*twcaNRRAL 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  73 IHAIGYMPEERGLYKKMKVGEQALYL-AQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSP 151
Cdd:NF000106  84 RRTIG*HRPVR*GRRESFSGRENLYMiGR*LDLSRKDARARADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRP 163

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 256041152 152 DLLILDEPFSGLDPINANLIKQEIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQIK 220
Cdd:NF000106 164 AVLYLDEPTTGLDPRTRNEVWDEVRSMVRDGATVLLTTQYMEEAEQLAHELTVIDRGRVIADGKVDELK 232
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
4-221 9.86e-19

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 86.72  E-value: 9.86e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEI-LFNGrpfdpqtDI--------- 73
Cdd:NF033858   2 ARLEGVSHRYGKTVALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRVeVLGG-------DMadarhrrav 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  74 -HAIGYMPEERG--LYKKMKVGEQALYLAQLKGMS--ERDAKdkikywfdkfeinswynkkVEEL--------------- 133
Cdd:NF033858  75 cPRIAYMPQGLGknLYPTLSVFENLDFFGRLFGQDaaERRRR-------------------IDELlratglapfadrpag 135

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 134 --SKGMQQKVQFISTIMHSPDLLILDEPFSGLDPinanLIKQEIFDL------SKNGTTIIFSTHRMEQVEEiCDRIVLV 205
Cdd:NF033858 136 klSGGMKQKLGLCCALIHDPDLLILDEPTTGVDP----LSRRQFWELidriraERPGMSVLVATAYMEEAER-FDWLVAM 210

                        250
                 ....*....|....*.
gi 256041152 206 NQGKKLLDGEVKQIKQ 221
Cdd:NF033858 211 DAGRVLATGTPAELLA 226
GguA NF040905
sugar ABC transporter ATP-binding protein;
3-216 2.98e-16

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 79.06  E-value: 2.98e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   3 LIEIKHLYKHYATH---KAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDK--GEILFNGRPFDPQTDIHAIG 77
Cdd:NF040905 257 VFEVKNWTVYHPLHperKVVDDVSLNVRRGEIVGIAGLMGAGRTELAMSVFGRSYGRNisGTVFKDGKEVDVSTVSDAID 336

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  78 ----YMPEER---GLYKKMKVGEQaLYLAQLKGMSERDAKDKIKywfdKFEINSWYNKK-----------VEELSKGMQQ 139
Cdd:NF040905 337 aglaYVTEDRkgyGLNLIDDIKRN-ITLANLGKVSRRGVIDENE----EIKVAEEYRKKmniktpsvfqkVGNLSGGNQQ 411

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 140 KVQFISTIMHSPDLLILDEPFSGLDpINAnliKQEIF----DLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGKklLDGE 215
Cdd:NF040905 412 KVVLSKWLFTDPDVLILDEPTRGID-VGA---KYEIYtiinELAAEGKGVIVISSELPELLGMCDRIYVMNEGR--ITGE 485


                 .
gi 256041152 216 V 216
Cdd:NF040905 486 L 486
GguA NF040905
sugar ABC transporter ATP-binding protein;
3-222 8.69e-10

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 59.42  E-value: 8.69e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   3 LIEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIfYPD---KGEILFNGRP--FDpqtDIHAig 77
Cdd:NF040905   1 ILEMRGITKTFPGVKALDDVNLSVREGEIHALCGENGAGKSTLMKVLSGV-YPHgsyEGEILFDGEVcrFK---DIRD-- 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  78 ymPEERG---------LYKKMKVGEQaLYLA--QLKGM------SERDAKDKIKywfdKFEINSWYNKKVEELSKGMQQK 140
Cdd:NF040905  75 --SEALGiviihqelaLIPYLSIAEN-IFLGneRAKRGvidwneTNRRARELLA----KVGLDESPDTLVTDIGVGKQQL 147

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 141 VQFISTIMHSPDLLILDEPFSGL-DPINANLIKQeIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGK--KLLDGEVK 217
Cdd:NF040905 148 VEIAKALSKDVKLLILDEPTAALnEEDSAALLDL-LLELKAQGITSIIISHKLNEIRRVADSITVLRDGRtiETLDCRAD 226


                 ....*
gi 256041152 218 QIKQD 222
Cdd:NF040905 227 EVTED 231
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 28-204 2.95e-09

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 55.07  E-value: 2.95e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152    28 KGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFngrpFDPQTDIHAIGYMPEERGLYKKMKVGEQALYLaqlkgmseR 107
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPGGGVIY----IDGEDILEEVLDQLLLIIVGGKKASGSGELRL--------R 68

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   108 DAKDKIKYwfdkfeinswynkkveelskgmqqkvqfistimHSPDLLILDEPFSGLDPINANLIKQEIFD------LSKN 181
Cdd:smart00382  69 LALALARK---------------------------------LKPDVLILDEITSLLDAEQEALLLLLEELrlllllKSEK 115

                          170       180
                   ....*....|....*....|...
gi 256041152   182 GTTIIFSTHRMEQVEEICDRIVL 204
Cdd:smart00382 116 NLTVILTTNDEKDLGPALLRRRF 138
 
Name Accession Description Interval E-value
YhaQ COG4152
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 4-299 5.22e-173

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443322 [Multi-domain]  Cd Length: 298  Bit Score: 481.15  E-value: 5.22e-173
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPQtDIHAIGYMPEER 83
Cdd:COG4152    2 LELKGLTKRFGDKTAVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGEVLWDGEPLDPE-DRRRIGYLPEER 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  84 GLYKKMKVGEQALYLAQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEPFSGL 163
Cdd:COG4152   81 GLYPKMKVGEQLVYLARLKGLSKAEAKRRADEWLERLGLGDRANKKVEELSKGNQQKVQLIAALLHDPELLILDEPFSGL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 164 DPINANLIKQEIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQIKQDFKQHLFRIGFGVMPNFAQvAT 243
Cdd:COG4152  161 DPVNVELLKDVIRELAAKGTTVIFSSHQMELVEELCDRIVIINKGRKVLSGSVDEIRRQFGRNTLRLEADGDAGWLR-AL 239

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 256041152 244 HHFSIIKQEPLAYTVKLTEGSTNNDILAHFIRHnVPITSFQEILPSINEVFIQQVT 299
Cdd:COG4152  240 PGVTVVEEDGDGAELKLEDGADAQELLRALLAR-GPVREFEEVRPSLNEIFIEVVG 294
ABC_putative_ATPase cd03269
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ...
 4-214 2.02e-122

ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213236 [Multi-domain]  Cd Length: 210  Bit Score: 349.66  E-value: 2.02e-122
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPQtDIHAIGYMPEER 83
Cdd:cd03269    1 LEVENVTKRFGRVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFDGKPLDIA-ARNRIGYLPEER 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  84 GLYKKMKVGEQALYLAQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEPFSGL 163
Cdd:cd03269   80 GLYPKMKVIDQLVYLAQLKGLKKEEARRRIDEWLERLELSEYANKRVEELSKGNQQKVQFIAAVIHDPELLILDEPFSGL 159

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 256041152 164 DPINANLIKQEIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDG 214
Cdd:cd03269  160 DPVNVELLKDVIRELARAGKTVILSTHQMELVEELCDRVLLLNKGRAVLYG 210
CcmA COG1131
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
4-223 1.20e-96

ABC-type multidrug transport system, ATPase component [Defense mechanisms];


Pssm-ID: 440746 [Multi-domain]  Cd Length: 236  Bit Score: 285.42  E-value: 1.20e-96
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGrpFDPQTDIHA----IGYM 79
Cdd:COG1131    1 IEVRGLTKRYGDKTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVLG--EDVARDPAEvrrrIGYV 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  80 PEERGLYKKMKVGEQALYLAQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEP 159
Cdd:COG1131   79 PQEPALYPDLTVRENLRFFARLYGLPRKEARERIDELLELFGLTDAADRKVGTLSGGMKQRLGLALALLHDPELLILDEP 158

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 256041152 160 FSGLDPINANLIKQEIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQIKQDF 223
Cdd:COG1131  159 TSGLDPEARRELWELLRELAAEGKTVLLSTHYLEEAERLCDRVAIIDKGRIVADGTPDELKARL 222
NatA COG4555
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ...
 3-230 1.28e-83

ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 443618 [Multi-domain]  Cd Length: 243  Bit Score: 252.47  E-value: 1.28e-83
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   3 LIEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRP--FDPQTDIHAIGYMP 80
Cdd:COG4555    1 MIEVENLSKKYGKVPALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILIDGEDvrKEPREARRQIGVLP 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  81 EERGLYKKMKVGEQALYLAQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEPF 160
Cdd:COG4555   81 DERGLYDRLTVRENIRYFAELYGLFDEELKKRIEELIELLGLEEFLDRRVGELSTGMKKKVALARALVHDPKVLLLDEPT 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 256041152 161 SGLDPINANLIKQEIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQIKQ-----DFKQHLFRI 230
Cdd:COG4555  161 NGLDVMARRLLREILRALKKEGKTVLFSSHIMQEVEALCDRVVILHKGKVVAQGSLDELREeigeeNLEDAFVAL 235
ABC_DR_subfamily_A cd03230
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ...
 4-209 1.16e-76

ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213197 [Multi-domain]  Cd Length: 173  Bit Score: 232.29  E-value: 1.16e-76
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGrpFDPQTDIHA----IGYM 79
Cdd:cd03230    1 IEVRNLSKRYGKKTALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKVLG--KDIKKEPEEvkrrIGYL 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  80 PEERGLYKKMKVGEqalYLaqlkgmserdakdkikywfdkfeinswynkkveELSKGMQQKVQFISTIMHSPDLLILDEP 159
Cdd:cd03230   79 PEEPSLYENLTVRE---NL---------------------------------KLSGGMKQRLALAQALLHDPELLILDEP 122

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 256041152 160 FSGLDPINANLIKQEIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGK 209
Cdd:cd03230  123 TSGLDPESRREFWELLRELKKEGKTILLSSHILEEAERLCDRVAILNNGR 172
ABC_NatA_sodium_exporter cd03266
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ...
 3-214 4.35e-67

ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.


Pssm-ID: 213233 [Multi-domain]  Cd Length: 218  Bit Score: 209.53  E-value: 4.35e-67
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   3 LIEIKHLYKHY----ATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGrpFD----PQTDIH 74
Cdd:cd03266    1 MITADALTKRFrdvkKTVQAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATVDG--FDvvkePAEARR 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  75 AIGYMPEERGLYKKMKVGEQALYLAQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLL 154
Cdd:cd03266   79 RLGFVSDSTGLYDRLTARENLEYFAGLYGLKGDELTARLEELADRLGMEELLDRRVGGFSTGMRQKVAIARALVHDPPVL 158

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 155 ILDEPFSGLDPINANLIKQEIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDG 214
Cdd:cd03266  159 LLDEPTTGLDVMATRALREFIRQLRALGKCILFSTHIMQEVERLCDRVVVLHRGRVVYEG 218
drrA TIGR01188
daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin ...
 11-303 7.47e-63

daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin resistance ABC transporter, ATP binding subunit in bacteria and archaea. This model is restricted in its scope to preferentially recognize the ATP binding subunit associated with effux of the drug, daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins, multidrug resistance protein etc. [Transport and binding proteins, Other]


Pssm-ID: 130256 [Multi-domain]  Cd Length: 302  Bit Score: 201.46  E-value: 7.47e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   11 KHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPF--DPQTDIHAIGYMPEERGLYKK 88
Cdd:TIGR01188   1 KVYGDFKAVDGVNFKVREGEVFGFLGPNGAGKTTTIRMLTTLLRPTSGTARVAGYDVvrEPRKVRRSIGIVPQYASVDED 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   89 MkVGEQALYL-AQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEPFSGLDPIN 167
Cdd:TIGR01188  81 L-TGRENLEMmGRLYGLPKDEAEERAEELLELFELGEAADRPVGTYSGGMRRRLDIAASLIHQPDVLFLDEPTTGLDPRT 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  168 ANLIKQEIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQIKQ----DFKQHLFRIGFGVMPN----FA 239
Cdd:TIGR01188 160 RRAIWDYIRALKEEGVTILLTTHYMEEADKLCDRIAIIDHGRIIAEGTPEELKRrlgkDTLESRPRDIQSLKVEvsmlIA 239

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 256041152  240 QVATHHFSIIKQEPLAYTVKLTEG---STNNDILAHFIRHNVPITSFQEILPSINEVFIqqvtSMTG 303
Cdd:TIGR01188 240 ELGETGLGLLAVTVDSDRIKILVPdgdETVPEIVEAAIRNGIRIRSISTERPSLDDVFL----KLTG 302
ABC_subfamily_A cd03263
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ...
 4-220 3.46e-61

ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.


Pssm-ID: 213230 [Multi-domain]  Cd Length: 220  Bit Score: 194.26  E-value: 3.46e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYA--THKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGrpFDPQTDIHA----IG 77
Cdd:cd03263    1 LQIRNLTKTYKkgTKPAVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYING--YSIRTDRKAarqsLG 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  78 YMPEERGLYKKMKVGEQALYLAQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILD 157
Cdd:cd03263   79 YCPQFDALFDELTVREHLRFYARLKGLPKSEIKEEVELLLRVLGLTDKANKRARTLSGGMKRKLSLAIALIGGPSVLLLD 158

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 256041152 158 EPFSGLDPInanlIKQEIFDL---SKNGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQIK 220
Cdd:cd03263  159 EPTSGLDPA----SRRAIWDLileVRKGRSIILTTHSMDEAEALCDRIAIMSDGKLRCIGSPQELK 220
ABC_drug_resistance_like cd03264
ABC-type multidrug transport system, ATPase component; The biological function of this family ...
 4-214 5.97e-60

ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213231 [Multi-domain]  Cd Length: 211  Bit Score: 190.87  E-value: 5.97e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYATHKAVDDISFAIPKGsIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPF--DPQTDIHAIGYMPE 81
Cdd:cd03264    1 LQLENLTKRYGKKRALDGVSLTLGPG-MYGLLGPNGAGKTTLMRILATLTPPSSGTIRIDGQDVlkQPQKLRRRIGYLPQ 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  82 ERGLYKKMKVGEQALYLAQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEPFS 161
Cdd:cd03264   80 EFGVYPNFTVREFLDYIAWLKGIPSKEVKARVDEVLELVNLGDRAKKKIGSLSGGMRRRVGIAQALVGDPSILIVDEPTA 159

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 256041152 162 GLDPINANLIKQEIFDLSKNgTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDG 214
Cdd:cd03264  160 GLDPEERIRFRNLLSELGED-RIVILSTHIVEDVESLCNQVAVLNKGKLVFEG 211
EcfA2 COG1122
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ...
 4-219 6.07e-55

Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];


Pssm-ID: 440739 [Multi-domain]  Cd Length: 230  Bit Score: 178.68  E-value: 6.07e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYA-THKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPQT--DIHA-IGYM 79
Cdd:COG1122    1 IELENLSFSYPgGTPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVDGKDITKKNlrELRRkVGLV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  80 ---PEErglykkmkvgeQ----------ALYLAQLkGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFIST 146
Cdd:COG1122   81 fqnPDD-----------QlfaptveedvAFGPENL-GLPREEIRERVEEALELVGLEHLADRPPHELSGGQKQRVAIAGV 148

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 256041152 147 IMHSPDLLILDEPFSGLDPINANLIKQEIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQI 219
Cdd:COG1122  149 LAMEPEVLVLDEPTAGLDPRGRRELLELLKRLNKEGKTVIIVTHDLDLVAELADRVIVLDDGRIVADGTPREV 221
ABC_BcrA_bacitracin_resist cd03268
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ...
 4-214 8.30e-54

ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.


Pssm-ID: 213235 [Multi-domain]  Cd Length: 208  Bit Score: 175.10  E-value: 8.30e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGR-PFDPQTDIHAIGYMPEE 82
Cdd:cd03268    1 LKTNDLTKTYGKKRVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEITFDGKsYQKNIEALRRIGALIEA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  83 RGLYKKMKVGEQALYLAQLKGMSERDAKDKIkywfDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEPFSG 162
Cdd:cd03268   81 PGFYPNLTARENLRLLARLLGIRKKRIDEVL----DVVGLKDSAKKKVKGFSLGMKQRLGIALALLGNPDLLILDEPTNG 156

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 256041152 163 LDPINANLIKQEIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDG 214
Cdd:cd03268  157 LDPDGIKELRELILSLRDQGITVLISSHLLSEIQKVADRIGIINKGKLIEEG 208
ZnuC COG1121
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ...
 1-208 2.95e-51

ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440738 [Multi-domain]  Cd Length: 245  Bit Score: 169.50  E-value: 2.95e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   1 MNLIEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPfdPQTDIHAIGYMP 80
Cdd:COG1121    4 MPAIELENLTVSYGGRPVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRLFGKP--PRRARRRIGYVP 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  81 EER----------------GLYKKMKVgeqalylaqLKGMSERDaKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVqFI 144
Cdd:COG1121   82 QRAevdwdfpitvrdvvlmGRYGRRGL---------FRRPSRAD-REAVDEALERVGLEDLADRPIGELSGGQQQRV-LL 150

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 256041152 145 S-TIMHSPDLLILDEPFSGLDPINANLIKQEIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQG 208
Cdd:COG1121  151 ArALAQDPDLLLLDEPFAGVDAATEEALYELLRELRREGKTILVVTHDLGAVREYFDRVLLLNRG 215
MlaF COG1127
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ...
 2-221 4.50e-51

ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440744 [Multi-domain]  Cd Length: 241  Bit Score: 169.00  E-value: 4.50e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   2 NLIEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRpfdpqtDIHA------ 75
Cdd:COG1127    4 PMIEVRNLTKSFGDRVVLDGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSGEILVDGQ------DITGlsekel 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  76 ------IGYMPEERGLYKKMKVGEQ-ALYLAQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIM 148
Cdd:COG1127   78 yelrrrIGMLFQGGALFDSLTVFENvAFPLREHTDLSEAEIRELVLEKLELVGLPGAADKMPSELSGGMRKRVALARALA 157

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 256041152 149 HSPDLLILDEPFSGLDPINANLIKQEIFDLSKN-GTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQIKQ 221
Cdd:COG1127  158 LDPEILLYDEPTAGLDPITSAVIDELIRELRDElGLTSVVVTHDLDSAFAIADRVAVLADGKIIAEGTPEELLA 231
ABC_cobalt_CbiO_domain1 cd03225
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ...
 5-209 1.05e-50

First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213192 [Multi-domain]  Cd Length: 211  Bit Score: 166.87  E-value: 1.05e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   5 EIKHLYKHYATH--KAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPQTDIHA---IGYM 79
Cdd:cd03225    1 ELKNLSFSYPDGarPALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDGKDLTKLSLKELrrkVGLV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  80 ---PEeRGLYKKMkVGEQALYLAQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLIL 156
Cdd:cd03225   81 fqnPD-DQFFGPT-VEEEVAFGLENLGLPEEEIEERVEEALELVGLEGLRDRSPFTLSGGQKQRVAIAGVLAMDPDILLL 158

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 256041152 157 DEPFSGLDPINANLIKQEIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGK 209
Cdd:cd03225  159 DEPTAGLDPAGRRELLELLKKLKAEGKTIIIVTHDLDLLLELADRVIVLEDGK 211
ABC_Class3 cd03229
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ...
 4-209 1.33e-50

ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213196 [Multi-domain]  Cd Length: 178  Bit Score: 165.82  E-value: 1.33e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPQTDIH-----AIGY 78
Cdd:cd03229    1 LELKNVSKRYGQKTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIDGEDLTDLEDELpplrrRIGM 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  79 MPEERGLYKKMKVGEQALYLaqlkgmserdakdkikywfdkfeinswynkkveeLSKGMQQKVQFISTIMHSPDLLILDE 158
Cdd:cd03229   81 VFQDFALFPHLTVLENIALG----------------------------------LSGGQQQRVALARALAMDPDVLLLDE 126

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 256041152 159 PFSGLDPINANLIKQEIFDLSKN-GTTIIFSTHRMEQVEEICDRIVLVNQGK 209
Cdd:cd03229  127 PTSALDPITRREVRALLKSLQAQlGITVVLVTHDLDEAARLADRVVVLRDGK 178
ABC_Carb_Solutes_like cd03259
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ...
 4-209 2.89e-50

ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213226 [Multi-domain]  Cd Length: 213  Bit Score: 166.16  E-value: 2.89e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFdpqTDIHA----IGYM 79
Cdd:cd03259    1 LELKGLSKTYGSVRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILIDGRDV---TGVPPerrnIGMV 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  80 PEERGLYKKMKVGEQALYLAQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEP 159
Cdd:cd03259   78 FQDYALFPHLTVAENIAFGLKLRGVPKAEIRARVRELLELVGLEGLLNRYPHELSGGQQQRVALARALAREPSLLLLDEP 157

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 256041152 160 FSGLDPINANLIKQEIFDLSKN-GTTIIFSTHRMEQVEEICDRIVLVNQGK 209
Cdd:cd03259  158 LSALDAKLREELREELKELQRElGITTIYVTHDQEEALALADRIAVMNEGR 208
ABC_NrtD_SsuB_transporters cd03293
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ...
 4-204 4.82e-50

ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213260 [Multi-domain]  Cd Length: 220  Bit Score: 165.72  E-value: 4.82e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYAT----HKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPQTdiHAIGYM 79
Cdd:cd03293    1 LEVRNVSKTYGGgggaVTALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLVDGEPVTGPG--PDRGYV 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  80 PEERGLYKKMKVGEQALYLAQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEP 159
Cdd:cd03293   79 FQQDALLPWLTVLDNVALGLELQGVPKAEARERAEELLELVGLSGFENAYPHQLSGGMRQRVALARALAVDPDVLLLDEP 158

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 256041152 160 FSGLDPINANLIKQEIFDL-SKNGTTIIFSTHrmeQVEE---ICDRIVL 204
Cdd:cd03293  159 FSALDALTREQLQEELLDIwRETGKTVLLVTH---DIDEavfLADRVVV 204
ABC_DrrA cd03265
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ...
 4-220 1.28e-49

Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213232 [Multi-domain]  Cd Length: 220  Bit Score: 164.47  E-value: 1.28e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPF--DPQTDIHAIGYMPE 81
Cdd:cd03265    1 IEVENLVKKYGDFEAVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRATVAGHDVvrEPREVRRRIGIVFQ 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  82 ERGLYKKMKVGEQALYLAQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEPFS 161
Cdd:cd03265   81 DLSVDDELTGWENLYIHARLYGVPGAERRERIDELLDFVGLLEAADRLVKTYSGGMRRRLEIARSLVHRPEVLFLDEPTI 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 162 GLDPINANLIKQEIFDLSK-NGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQIK 220
Cdd:cd03265  161 GLDPQTRAHVWEYIEKLKEeFGMTILLTTHYMEEAEQLCDRVAIIDHGRIIAEGTPEELK 220
ABC_Org_Solvent_Resistant cd03261
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ...
 4-221 2.99e-49

ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213228 [Multi-domain]  Cd Length: 235  Bit Score: 164.21  E-value: 2.99e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDP------QTDIHAIG 77
Cdd:cd03261    1 IELRGLTKSFGGRTVLKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDGEDISGlseaelYRLRRRMG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  78 YMPEERGLYKKMKVGEQ-ALYLAQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLIL 156
Cdd:cd03261   81 MLFQSGALFDSLTVFENvAFPLREHTRLSEEEIREIVLEKLEAVGLRGAEDLYPAELSGGMKKRVALARALALDPELLLY 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 256041152 157 DEPFSGLDPINANLIKQEIFDLSK-NGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQIKQ 221
Cdd:cd03261  161 DEPTAGLDPIASGVIDDLIRSLKKeLGLTSIMVTHDLDTAFAIADRIAVLYDGKIVAEGTPEELRA 226
ABC_ATPase cd00267
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ...
 5-209 8.57e-49

ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213179 [Multi-domain]  Cd Length: 157  Bit Score: 160.49  E-value: 8.57e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   5 EIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPQTDIHA---IGYMPE 81
Cdd:cd00267    1 EIENLSFRYGGRTALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDGKDIAKLPLEELrrrIGYVPQ 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  82 erglykkmkvgeqalylaqlkgmserdakdkikywfdkfeinswynkkveeLSKGMQQKVQFISTIMHSPDLLILDEPFS 161
Cdd:cd00267   81 ---------------------------------------------------LSGGQRQRVALARALLLNPDLLLLDEPTS 109

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 256041152 162 GLDPINANLIKQEIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGK 209
Cdd:cd00267  110 GLDPASRERLLELLRELAEEGRTVIIVTHDPELAELAADRVIVLKDGK 157
galliderm_ABC TIGR03740
gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Model TIGR03731 ...
 4-218 4.03e-48

gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Model TIGR03731 represents the family of all lantibiotics related to gallidermin, including epidermin, mutatin, and nisin. This protein family describes the ATP-binding subunit of a gallidermin/epidermin class lantibiotic protection transporter. It is largely restricted to gallidermin-family lantibiotic biosynthesis and export cassettes, but also occurs in orphan transporter cassettes in species that lack candidate lantibiotic precursor and synthetase genes.


Pssm-ID: 163452 [Multi-domain]  Cd Length: 223  Bit Score: 161.03  E-value: 4.03e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152    4 IEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDpQTDIHAIGYMPEER 83
Cdd:TIGR03740   1 LETKNLSKRFGKQTAVNNISLTVPKNSVYGLLGPNGAGKSTLLKMITGILRPTSGEIIFDGHPWT-RKDLHKIGSLIESP 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   84 GLYKKMKVGEQALYLAQLKGMSErdakDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEPFSGL 163
Cdd:TIGR03740  80 PLYENLTARENLKVHTTLLGLPD----SRIDEVLNIVDLTNTGKKKAKQFSLGMKQRLGIAIALLNHPKLLILDEPTNGL 155

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 256041152  164 DPINANLIKQEIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQ 218
Cdd:TIGR03740 156 DPIGIQELRELIRSFPEQGITVILSSHILSEVQQLADHIGIISEGVLGYQGKINK 210
LivG COG0411
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ...
 1-222 7.91e-48

ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];


Pssm-ID: 440180 [Multi-domain]  Cd Length: 257  Bit Score: 160.97  E-value: 7.91e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   1 MNLIEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRpfdpqtDIHaiGYMP 80
Cdd:COG0411    2 DPLLEVRGLTKRFGGLVAVDDVSLEVERGEIVGLIGPNGAGKTTLFNLITGFYRPTSGRILFDGR------DIT--GLPP 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  81 EER---G---------LYKKMKVGEqALYLAQLKGM----------------SERDAKDKIKYWFDKFEINSWYNKKVEE 132
Cdd:COG0411   74 HRIarlGiartfqnprLFPELTVLE-NVLVAAHARLgrgllaallrlprarrEEREARERAEELLERVGLADRADEPAGN 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 133 LSKGMQQKVQFISTIMHSPDLLILDEPFSGLDPINANLIKQEIFDLSKN-GTTIIFSTHRMEQVEEICDRIVLVNQGKKL 211
Cdd:COG0411  153 LSYGQQRRLEIARALATEPKLLLLDEPAAGLNPEETEELAELIRRLRDErGITILLIEHDMDLVMGLADRIVVLDFGRVI 232

                        250
                 ....*....|.
gi 256041152 212 LDGEVKQIKQD 222
Cdd:COG0411  233 AEGTPAEVRAD 243
COG4586 COG4586
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 4-293 2.34e-47

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443643 [Multi-domain]  Cd Length: 323  Bit Score: 161.79  E-value: 2.34e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYATHK---------------------AVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILF 62
Cdd:COG4586    2 IEVENLSKTYRVYEkepglkgalkglfrreyreveAVDDISFTIEPGEIVGFIGPNGAGKSTTIKMLTGILVPTSGEVRV 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  63 NGrpFDPQtdihaigymPEERGLYKKMKV--G------------EQALYLAQLKGMSERDAKDKIKYWFDKFEINSWYNK 128
Cdd:COG4586   82 LG--YVPF---------KRRKEFARRIGVvfGqrsqlwwdlpaiDSFRLLKAIYRIPDAEYKKRLDELVELLDLGELLDT 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 129 KVEELSKGMQQKVQFISTIMHSPDLLILDEPFSGLDPINANLIKQEIFDLSK-NGTTIIFSTHRMEQVEEICDRIVLVNQ 207
Cdd:COG4586  151 PVRQLSLGQRMRCELAAALLHRPKILFLDEPTIGLDVVSKEAIREFLKEYNReRGTTILLTSHDMDDIEALCDRVIVIDH 230

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 208 GKKLLDGEVKQIKQDF-KQHLFRIGFGVMPNFAQVAtHHFSIIKQEPLAYTVKLTEGSTNNDILAHFIRHNvPIT--SFQ 284
Cdd:COG4586  231 GRIIYDGSLEELKERFgPYKTIVLELAEPVPPLELP-RGGEVIEREGNRVRLEVDPRESLAEVLARLLARY-PVRdlTIE 308


                 ....*....
gi 256041152 285 EilPSINEV 293
Cdd:COG4586  309 E--PPIEEV 315
ABC_Mj1267_LivG_branched cd03219
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ...
 4-222 1.18e-46

ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).


Pssm-ID: 213186 [Multi-domain]  Cd Length: 236  Bit Score: 157.60  E-value: 1.18e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRpfdpqtDIhaIGYMPEER 83
Cdd:cd03219    1 LEVRGLTKRFGGLVALDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSVLFDGE------DI--TGLPPHEI 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  84 ------------GLYKKM------KVGEQA----LYLAQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKV 141
Cdd:cd03219   73 arlgigrtfqipRLFPELtvlenvMVAAQArtgsGLLLARARREEREARERAEELLERVGLADLADRPAGELSYGQQRRL 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 142 QFISTIMHSPDLLILDEPFSGLDPINANLIKQEIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQIKQ 221
Cdd:cd03219  153 EIARALATDPKLLLLDEPAAGLNPEETEELAELIRELRERGITVLLVEHDMDVVMSLADRVTVLDQGRVIAEGTPDEVRN 232


                 .
gi 256041152 222 D 222
Cdd:cd03219  233 N 233
TauB COG1116
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ...
 1-204 2.26e-46

ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440733 [Multi-domain]  Cd Length: 260  Bit Score: 157.56  E-value: 2.26e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   1 MNLIEIKHLYKHYAT----HKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFD-PQTDiha 75
Cdd:COG1116    5 APALELRGVSKRFPTggggVTALDDVSLTVAAGEFVALVGPSGCGKSTLLRLIAGLEKPTSGEVLVDGKPVTgPGPD--- 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  76 IGYMPEERGLYKKMKVGEQALYLAQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLI 155
Cdd:COG1116   82 RGVVFQEPALLPWLTVLDNVALGLELRGVPKAERRERARELLELVGLAGFEDAYPHQLSGGMRQRVAIARALANDPEVLL 161

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 256041152 156 LDEPFSGLDPINANLIKQEIFDL-SKNGTTIIFSTHrmeQVEE---ICDRIVL 204
Cdd:COG1116  162 MDEPFGALDALTRERLQDELLRLwQETGKTVLFVTH---DVDEavfLADRVVV 211
ABC_Metallic_Cations cd03235
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ...
 5-208 3.17e-46

ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.


Pssm-ID: 213202 [Multi-domain]  Cd Length: 213  Bit Score: 155.77  E-value: 3.17e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   5 EIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPfdPQTDIHAIGYMPEER- 83
Cdd:cd03235    1 EVEDLTVSYGGHPVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRVFGKP--LEKERKRIGYVPQRRs 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  84 ---------------GLYKKMKVgeqalylaqLKGMSERDaKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIM 148
Cdd:cd03235   79 idrdfpisvrdvvlmGLYGHKGL---------FRRLSKAD-KAKVDEALERVGLSELADRQIGELSGGQQQRVLLARALV 148

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 149 HSPDLLILDEPFSGLDPINANLIKQEIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQG 208
Cdd:cd03235  149 QDPDLLLLDEPFAGVDPKTQEDIYELLRELRREGMTILVVTHDLGLVLEYFDRVLLLNRT 208
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
 3-219 5.81e-46

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 162.77  E-value: 5.81e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   3 LIEIKHLYKHYATH-----KAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPQTDI---- 73
Cdd:COG1123  260 LLEVRNLSKRYPVRgkggvRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRPTSGSILFDGKDLTKLSRRslre 339

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  74 --HAIGY---MPeERGLYKKMKVGEQ-ALYLAQLKGMSERDAKDKIKYWFDKFEINSWY-NKKVEELSKGMQQKVQFIST 146
Cdd:COG1123  340 lrRRVQMvfqDP-YSSLNPRMTVGDIiAEPLRLHGLLSRAERRERVAELLERVGLPPDLaDRYPHELSGGQRQRVAIARA 418

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 256041152 147 IMHSPDLLILDEPFSGLDPINA----NLIKqeifDLSKN-GTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQI 219
Cdd:COG1123  419 LALEPKLLILDEPTSALDVSVQaqilNLLR----DLQRElGLTYLFISHDLAVVRYIADRVAVMYDGRIVEDGPTEEV 492
PRK13537 PRK13537
nodulation factor ABC transporter ATP-binding protein NodI;
4-214 1.33e-45

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237420 [Multi-domain]  Cd Length: 306  Bit Score: 156.89  E-value: 1.33e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFdPQTDIHA---IGYMP 80
Cdd:PRK13537   8 IDFRNVEKRYGDKLVVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLCGEPV-PSRARHArqrVGVVP 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  81 EERGLYKKMKVGEQALYLAQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEPF 160
Cdd:PRK13537  87 QFDNLDPDFTVRENLLVFGRYFGLSAAAARALVPPLLEFAKLENKADAKVGELSGGMKRRLTLARALVNDPDVLVLDEPT 166

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 256041152 161 SGLDPINANLIKQEIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDG 214
Cdd:PRK13537 167 TGLDPQARHLMWERLRSLLARGKTILLTTHFMEEAERLCDRLCVIEEGRKIAEG 220
ABC_YhbG cd03218
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ...
 4-222 1.43e-45

ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.


Pssm-ID: 213185 [Multi-domain]  Cd Length: 232  Bit Score: 154.62  E-value: 1.43e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPQTdIHA-----IGY 78
Cdd:cd03218    1 LRAENLSKRYGKRKVVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILLDGQDITKLP-MHKrarlgIGY 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  79 MPEERGLYKKMKVGEQALYLAQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDE 158
Cdd:cd03218   80 LPQEASIFRKLTVEENILAVLEIRGLSKKEREEKLEELLEEFHITHLRKSKASSLSGGERRRVEIARALATNPKFLLLDE 159

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 256041152 159 PFSGLDPINANLIKQEIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQIKQD 222
Cdd:cd03218  160 PFAGVDPIAVQDIQKIIKILKDRGIGVLITDHNVRETLSITDRAYIIYEGKVLAEGTPEEIAAN 223
PotA COG3842
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...
 1-209 3.11e-44

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443052 [Multi-domain]  Cd Length: 353  Bit Score: 154.49  E-value: 3.11e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   1 MNLIEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRpfdpqtDIHAIGymP 80
Cdd:COG3842    3 MPALELENVSKRYGDVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGR------DVTGLP--P 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  81 EERG---------LYKKMKVGEQ-ALYLaQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHS 150
Cdd:COG3842   75 EKRNvgmvfqdyaLFPHLTVAENvAFGL-RMRGVPKAEIRARVAELLELVGLEGLADRYPHQLSGGQQQRVALARALAPE 153

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 256041152 151 PDLLILDEPFSGLDpinANLIKQ---EIFDL-SKNGTTIIFSTHRMEQVEEICDRIVLVNQGK 209
Cdd:COG3842  154 PRVLLLDEPLSALD---AKLREEmreELRRLqRELGITFIYVTHDQEEALALADRIAVMNDGR 213
ABC_Iron-Siderophores_B12_Hemin cd03214
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ...
 5-214 6.27e-44

ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.


Pssm-ID: 213181 [Multi-domain]  Cd Length: 180  Bit Score: 148.35  E-value: 6.27e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   5 EIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRP---FDPQTDIHAIGYMPe 81
Cdd:cd03214    1 EVENLSVGYGGRTVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLDGKDlasLSPKELARKIAYVP- 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  82 erglykkmkvgeQALYLAQLKGMSERDakdkikywfdkfeinswynkkVEELSKGMQQKVQFISTIMHSPDLLILDEPFS 161
Cdd:cd03214   80 ------------QALELLGLAHLADRP---------------------FNELSGGERQRVLLARALAQEPPILLLDEPTS 126

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 256041152 162 GLDPINANLIKQEIFDLSK-NGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDG 214
Cdd:cd03214  127 HLDIAHQIELLELLRRLAReRGKTVVMVLHDLNLAARYADRVILLKDGRIVAQG 180
ABC_MJ0796_LolCDE_FtsE cd03255
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ...
 4-209 8.41e-44

ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.


Pssm-ID: 213222 [Multi-domain]  Cd Length: 218  Bit Score: 149.56  E-value: 8.41e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHY----ATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGrpfdpqTDIHAIGym 79
Cdd:cd03255    1 IELKNLSKTYggggEKVQALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDG------TDISKLS-- 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  80 PEERGLYKKMKVG---------------EQALYLAQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFI 144
Cdd:cd03255   73 EKELAAFRRRHIGfvfqsfnllpdltalENVELPLLLAGVPKKERRERAEELLERVGLGDRLNHYPSELSGGQQQRVAIA 152

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 256041152 145 STIMHSPDLLILDEPFSGLDPINANLIKQEIFDLSKN-GTTIIFSTHRMEqVEEICDRIVLVNQGK 209
Cdd:cd03255  153 RALANDPKIILADEPTGNLDSETGKEVMELLRELNKEaGTTIVVVTHDPE-LAEYADRIIELRDGK 217
ABC_Carb_Monos_I cd03216
First domain of the ATP-binding cassette component of monosaccharide transport system; This ...
 4-210 1.14e-43

First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213183 [Multi-domain]  Cd Length: 163  Bit Score: 147.19  E-value: 1.14e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPQTDIHAIgympeER 83
Cdd:cd03216    1 LELRGITKRFGGVKALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEILVDGKEVSFASPRDAR-----RA 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  84 GLykkmkvgeqalylaqlkGMserdakdkikywfdkfeinswynkkVEELSKGMQQKVQFISTIMHSPDLLILDEPFSGL 163
Cdd:cd03216   76 GI-----------------AM-------------------------VYQLSVGERQMVEIARALARNARLLILDEPTAAL 113

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 256041152 164 DPINA-NLIKQeIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGKK 210
Cdd:cd03216  114 TPAEVeRLFKV-IRRLRAQGVAVIFISHRLDEVFEIADRVTVLRDGRV 160
CysA COG1118
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ...
 4-209 1.87e-43

ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440735 [Multi-domain]  Cd Length: 348  Bit Score: 152.22  E-value: 1.87e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRpfDPQTDIHA----IGYM 79
Cdd:COG1118    3 IEVRNISKRFGSFTLLDDVSLEIASGELVALLGPSGSGKTTLLRIIAGLETPDSGRIVLNGR--DLFTNLPPrerrVGFV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  80 PEERGLYKKMKVGEQALYLAQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKV--------QfistimhsP 151
Cdd:COG1118   81 FQHYALFPHMTVAENIAFGLRVRPPSKAEIRARVEELLELVQLEGLADRYPSQLSGGQRQRValaralavE--------P 152

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 256041152 152 DLLILDEPFSGLDPINANLIKQEIFDL-SKNGTTIIFSTHRMEQVEEICDRIVLVNQGK 209
Cdd:COG1118  153 EVLLLDEPFGALDAKVRKELRRWLRRLhDELGGTTVFVTHDQEEALELADRVVVMNQGR 211
FepC COG1120
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ...
 3-219 3.94e-43

ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];


Pssm-ID: 440737 [Multi-domain]  Cd Length: 254  Bit Score: 148.65  E-value: 3.94e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   3 LIEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRpfdpqtDIHA------- 75
Cdd:COG1120    1 MLEAENLSVGYGGRPVLDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLLDGR------DLASlsrrela 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  76 --IGYMPEERGLYKKMKVGEQAL-----YLAQLKGMSERDaKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIM 148
Cdd:COG1120   75 rrIAYVPQEPPAPFGLTVRELVAlgrypHLGLFGRPSAED-REAVEEALERTGLEHLADRPVDELSGGERQRVLIARALA 153

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 256041152 149 HSPDLLILDEPFSGLDPINanliKQEIFDL-----SKNGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQI 219
Cdd:COG1120  154 QEPPLLLLDEPTSHLDLAH----QLEVLELlrrlaRERGRTVVMVLHDLNLAARYADRLVLLKDGRIVAQGPPEEV 225
ABC_NikE_OppD_transporters cd03257
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ...
 3-209 7.01e-43

ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.


Pssm-ID: 213224 [Multi-domain]  Cd Length: 228  Bit Score: 147.27  E-value: 7.01e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   3 LIEIKHLYKHYAT----HKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPQTDI----- 73
Cdd:cd03257    1 LLEVKNLSVSFPTgggsVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFDGKDLLKLSRRlrkir 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  74 -HAIGYMPEE--RGLYKKMKVGEQALYLAQLKGMSERDAKDKIKYWFDKFEIN---SWYNKKVEELSKGMQQKVQFISTI 147
Cdd:cd03257   81 rKEIQMVFQDpmSSLNPRMTIGEQIAEPLRIHGKLSKKEARKEAVLLLLVGVGlpeEVLNRYPHELSGGQRQRVAIARAL 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 256041152 148 MHSPDLLILDEPFSGLDPINANLIKQEIFDL-SKNGTTIIFSTHRMEQVEEICDRIVLVNQGK 209
Cdd:cd03257  161 ALNPKLLIADEPTSALDVSVQAQILDLLKKLqEELGLTLLFITHDLGVVAKIADRVAVMYAGK 223
LPS_export_lptB TIGR04406
LPS export ABC transporter ATP-binding protein; Members of this fmaily are LptB, the ...
 6-219 2.59e-42

LPS export ABC transporter ATP-binding protein; Members of this fmaily are LptB, the ATP-binding cassette protein of an ABC transporter involved in lipopolysaccharide export. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]


Pssm-ID: 275199 [Multi-domain]  Cd Length: 239  Bit Score: 146.27  E-value: 2.59e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152    6 IKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFdpqTD--IHA-----IGY 78
Cdd:TIGR04406   4 AENLIKSYKKRKVVNDVSLSVKSGEIVGLLGPNGAGKTTSFYMIVGLVRPDAGKILIDGQDI---THlpMHErarlgIGY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   79 MPEERGLYKKMKVGEQALYLAQLKGMSERDA-KDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILD 157
Cdd:TIGR04406  81 LPQEASIFRKLTVEENIMAVLEIRKDLDRAErEERLEALLEEFQISHLRDNKAMSLSGGERRRVEIARALATNPKFILLD 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 256041152  158 EPFSGLDPINANLIKQEIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQI 219
Cdd:TIGR04406 161 EPFAGVDPIAVGDIKKIIKHLKERGIGVLITDHNVRETLDICDRAYIISDGKVLAEGTPAEI 222
ABC_NatA_like cd03267
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ...
 4-214 4.35e-42

ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.


Pssm-ID: 213234 [Multi-domain]  Cd Length: 236  Bit Score: 145.55  E-value: 4.35e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYATHK---------------------AVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILF 62
Cdd:cd03267    1 IEVSNLSKSYRVYSkepgligslkslfkrkyreveALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVRV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  63 NG-RPFDPQTD-IHAIGYMPEERG-LYKKMKVGEQALYLAQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQ 139
Cdd:cd03267   81 AGlVPWKRRKKfLRRIGVVFGQKTqLWWDLPVIDSFYLLAAIYDLPPARFKKRLDELSELLDLEELLDTPVRQLSLGQRM 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 256041152 140 KVQFISTIMHSPDLLILDEPFSGLDPINANLIKQEIFDLSKN-GTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDG 214
Cdd:cd03267  161 RAEIAAALLHEPEILFLDEPTIGLDVVAQENIRNFLKEYNRErGTTVLLTSHYMKDIEALARRVLVIDKGRLLYDG 236
PRK13536 PRK13536
nodulation factor ABC transporter ATP-binding protein NodI;
4-214 4.42e-42

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237419 [Multi-domain]  Cd Length: 340  Bit Score: 148.44  E-value: 4.42e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPQTDI--HAIGYMPE 81
Cdd:PRK13536  42 IDLAGVSKSYGDKAVVNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKITVLGVPVPARARLarARIGVVPQ 121

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  82 ERGLYKKMKVGEQALYLAQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEPFS 161
Cdd:PRK13536 122 FDNLDLEFTVRENLLVFGRYFGMSTREIEAVIPSLLEFARLESKADARVSDLSGGMKRRLTLARALINDPQLLILDEPTT 201

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 256041152 162 GLDPINANLIKQEIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDG 214
Cdd:PRK13536 202 GLDPHARHLIWERLRSLLARGKTILLTTHFMEEAERLCDRLCVLEAGRKIAEG 254
LptB COG1137
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ...
 1-222 5.74e-42

ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440752 [Multi-domain]  Cd Length: 240  Bit Score: 145.17  E-value: 5.74e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   1 MNLIEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRpfdpqtDIHA----- 75
Cdd:COG1137    1 MMTLEAENLVKSYGKRTVVKDVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGRIFLDGE------DITHlpmhk 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  76 -----IGYMPEERGLYKKMKVGEQALYLAQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHS 150
Cdd:COG1137   75 rarlgIGYLPQEASIFRKLTVEDNILAVLELRKLSKKEREERLEELLEEFGITHLRKSKAYSLSGGERRRVEIARALATN 154

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 256041152 151 PDLLILDEPFSGLDPINANLIKQEIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQIKQD 222
Cdd:COG1137  155 PKFILLDEPFAGVDPIAVADIQKIIRHLKERGIGVLITDHNVRETLGICDRAYIISEGKVLAEGTPEEILNN 226
ABC_OpuCA_Osmoprotection cd03295
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ...
 4-209 6.21e-42

ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213262 [Multi-domain]  Cd Length: 242  Bit Score: 145.52  E-value: 6.21e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHY-ATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRP---FDPQTDIHAIGYM 79
Cdd:cd03295    1 IEFENVTKRYgGGKKAVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIFIDGEDireQDPVELRRKIGYV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  80 PEERGLYKKMKVGEQALYLAQLKGMSERDAKDKIKYWFD--KFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILD 157
Cdd:cd03295   81 IQQIGLFPHMTVEENIALVPKLLKWPKEKIRERADELLAlvGLDPAEFADRYPHELSGGQQQRVGVARALAADPPLLLMD 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 256041152 158 EPFSGLDPINANLIKQEIFDLSKN-GTTIIFSTHRMEQVEEICDRIVLVNQGK 209
Cdd:cd03295  161 EPFGALDPITRDQLQEEFKRLQQElGKTIVFVTHDIDEAFRLADRIAIMKNGE 213
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
 3-210 1.36e-41

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 150.56  E-value: 1.36e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   3 LIEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPQTDIHAIgympeE 82
Cdd:COG3845    5 ALELRGITKRFGGVVANDDVSLTVRPGEIHALLGENGAGKSTLMKILYGLYQPDSGEILIDGKPVRIRSPRDAI-----A 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  83 RG---------LYKKMKVGEQ-ALYLAQLKGM--SERDAKDKI-----KYwfdKFEINSwyNKKVEELSKGMQQKVQFIS 145
Cdd:COG3845   80 LGigmvhqhfmLVPNLTVAENiVLGLEPTKGGrlDRKAARARIrelseRY---GLDVDP--DAKVEDLSVGEQQRVEILK 154

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 256041152 146 TIMHSPDLLILDEPFSGLDPinanlikQEI---FD----LSKNGTTIIFSTHRMEQVEEICDRIVLVNQGKK 210
Cdd:COG3845  155 ALYRGARILILDEPTAVLTP-------QEAdelFEilrrLAAEGKSIIFITHKLREVMAIADRVTVLRRGKV 219
MalK COG3839
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ...
 1-209 6.01e-41

ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];


Pssm-ID: 443050 [Multi-domain]  Cd Length: 352  Bit Score: 145.99  E-value: 6.01e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   1 MNLIEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFdpqTDIHaigymP 80
Cdd:COG3839    1 MASLELENVSKSYGGVEALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPTSGEILIGGRDV---TDLP-----P 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  81 EERG---------LYKKMKVGEQ-ALYLaQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVqfiS---TI 147
Cdd:COG3839   73 KDRNiamvfqsyaLYPHMTVYENiAFPL-KLRKVPKAEIDRRVREAAELLGLEDLLDRKPKQLSGGQRQRV---AlgrAL 148

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 256041152 148 MHSPDLLILDEPFSGLDpinANL---IKQEIFDLSKN-GTTIIFSTHrmEQVE--EICDRIVLVNQGK 209
Cdd:COG3839  149 VREPKVFLLDEPLSNLD---AKLrveMRAEIKRLHRRlGTTTIYVTH--DQVEamTLADRIAVMNDGR 211
ABC_PotA_N cd03300
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ...
 4-209 1.30e-40

ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213267 [Multi-domain]  Cd Length: 232  Bit Score: 141.61  E-value: 1.30e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPfdpqtdIHAIGymPEER 83
Cdd:cd03300    1 IELENVSKFYGGFVALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDGKD------ITNLP--PHKR 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  84 G---------LYKKMKVGEQALYLAQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLL 154
Cdd:cd03300   73 PvntvfqnyaLFPHLTVFENIAFGLRLKKLPKAEIKERVAEALDLVQLEGYANRKPSQLSGGQQQRVAIARALVNEPKVL 152

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 256041152 155 ILDEPFSGLDpinANLIKQ---EIFDLSKN-GTTIIFSTHRMEQVEEICDRIVLVNQGK 209
Cdd:cd03300  153 LLDEPLGALD---LKLRKDmqlELKRLQKElGITFVFVTHDQEEALTMSDRIAVMNKGK 208
TagH COG1134
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ...
 11-229 1.66e-40

ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440749 [Multi-domain]  Cd Length: 245  Bit Score: 141.76  E-value: 1.66e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  11 KHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGR---PFDPQTdihaiGYMPEERGLyk 87
Cdd:COG1134   34 TRREEFWALKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTSGRVEVNGRvsaLLELGA-----GFHPELTGR-- 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  88 kmkvgEQALYLAQLKGMSERDAKDKIKYWFDkF-EINSWYNKKVEELSKGMQQKVQF-ISTIMHsPDLLILDEPFSGLDp 165
Cdd:COG1134  107 -----ENIYLNGRLLGLSRKEIDEKFDEIVE-FaELGDFIDQPVKTYSSGMRARLAFaVATAVD-PDILLVDEVLAVGD- 178

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 256041152 166 inANLIK---QEIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQIKQDFKQHLFR 229
Cdd:COG1134  179 --AAFQKkclARIRELRESGRTVIFVSHSMGAVRRLCDRAIWLEKGRLVMDGDPEEVIAAYEALLAG 243
ABC_PhnC_transporter cd03256
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ...
 4-228 1.93e-40

ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213223 [Multi-domain]  Cd Length: 241  Bit Score: 141.55  E-value: 1.93e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYAT-HKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNG--RPFDPQTDIHA----I 76
Cdd:cd03256    1 IEVENLSKTYPNgKKALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIDGtdINKLKGKALRQlrrqI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  77 GYMPEERGLYKKMKVGEQAL-----YLAQLKGM----SERDaKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTI 147
Cdd:cd03256   81 GMIFQQFNLIERLSVLENVLsgrlgRRSTWRSLfglfPKEE-KQRALAALERVGLLDKAYQRADQLSGGQQQRVAIARAL 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 148 MHSPDLLILDEPFSGLDPINANLIKQEIFDLSKN-GTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQIKQDFKQH 226
Cdd:cd03256  160 MQQPKLILADEPVASLDPASSRQVMDLLKRINREeGITVIVSLHQVDLAREYADRIVGLKDGRIVFDGPPAELTDEVLDE 239


                 ..
gi 256041152 227 LF 228
Cdd:cd03256  240 IY 241
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
 3-219 2.15e-40

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 147.74  E-value: 2.15e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   3 LIEIKHLYKHYA--THKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPD---KGEILFNGRP---FDPQTDIH 74
Cdd:COG1123    4 LLEVRDLSVRYPggDVPAVDGVSLTIAPGETVALVGESGSGKSTLALALMGLLPHGgriSGEVLLDGRDlleLSEALRGR 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  75 AIGYMPEERGLYKKM-KVGEQALYLAQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDL 153
Cdd:COG1123   84 RIGMVFQDPMTQLNPvTVGDQIAEALENLGLSRAEARARVLELLEAVGLERRLDRYPHQLSGGQRQRVAIAMALALDPDL 163

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 256041152 154 LILDEPFSGLDPINANLIKQEIFDLSKN-GTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQI 219
Cdd:COG1123  164 LIADEPTTALDVTTQAEILDLLRELQRErGTTVLLITHDLGVVAEIADRVVVMDDGRIVEDGPPEEI 230
CcmA COG4133
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ...
 3-190 6.67e-40

ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443308 [Multi-domain]  Cd Length: 206  Bit Score: 138.77  E-value: 6.67e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   3 LIEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPQTDIHA--IGYMP 80
Cdd:COG4133    2 MLEAENLSCRRGERLLFSGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLWNGEPIRDAREDYRrrLAYLG 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  81 EERGLYKKMKVGEQALYLAQLKGMseRDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEPF 160
Cdd:COG4133   82 HADGLKPELTVRENLRFWAALYGL--RADREAIDEALEAVGLAGLADLPVRQLSAGQKRRVALARLLLSPAPLWLLDEPF 159

                        170       180       190
                 ....*....|....*....|....*....|
gi 256041152 161 SGLDPINANLIKQEIFDLSKNGTTIIFSTH 190
Cdd:COG4133  160 TALDAAGVALLAELIAAHLARGGAVLLTTH 189
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
3-222 1.35e-39

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 145.16  E-value: 1.35e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   3 LIEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPQTDIHA----IGY 78
Cdd:COG1129    4 LLEMRGISKSFGGVKALDGVSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDSGEILLDGEPVRFRSPRDAqaagIAI 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  79 MPEERGLYKKMKVGEqALYLAQL---------KGMsERDAKDKIKYWfdKFEINSwyNKKVEELSKGMQQKVQFISTIMH 149
Cdd:COG1129   84 IHQELNLVPNLSVAE-NIFLGREprrgglidwRAM-RRRARELLARL--GLDIDP--DTPVGDLSVAQQQLVEIARALSR 157

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 256041152 150 SPDLLILDEPFSGLDPINA-NLIKQeIFDLSKNGTTIIFSTHRMEQVEEICDRI-VLVNqGKKLLDGEVKQIKQD 222
Cdd:COG1129  158 DARVLILDEPTASLTEREVeRLFRI-IRRLKAQGVAIIYISHRLDEVFEIADRVtVLRD-GRLVGTGPVAELTED 230
ABC_TM1139_LivF_branched cd03224
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ...
 4-222 4.19e-39

ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.


Pssm-ID: 213191 [Multi-domain]  Cd Length: 222  Bit Score: 137.18  E-value: 4.19e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFD--PQTDI--HAIGYM 79
Cdd:cd03224    1 LEVENLNAGYGKSQILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFDGRDITglPPHERarAGIGYV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  80 PEERGLYKKMKVGEQaLYLAQLKGmSERDAKDKIKYWFDKF----EInswYNKKVEELSKGMQQKVQFISTIMHSPDLLI 155
Cdd:cd03224   81 PEGRRIFPELTVEEN-LLLGAYAR-RRAKRKARLERVYELFprlkER---RKQLAGTLSGGEQQMLAIARALMSRPKLLL 155

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 256041152 156 LDEPFSGLDPInanlIKQEIFD----LSKNGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQIKQD 222
Cdd:cd03224  156 LDEPSEGLAPK----IVEEIFEaireLRDEGVTILLVEQNARFALEIADRAYVLERGRVVLEGTAAELLAD 222
ABC_MalK_N cd03301
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ...
 4-209 4.34e-39

The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.


Pssm-ID: 213268 [Multi-domain]  Cd Length: 213  Bit Score: 137.00  E-value: 4.34e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFdpqTDIHaigymPEER 83
Cdd:cd03301    1 VELENVTKRFGNVTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYIGGRDV---TDLP-----PKDR 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  84 G---------LYKKMKVGEQALYLAQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLL 154
Cdd:cd03301   73 DiamvfqnyaLYPHMTVYDNIAFGLKLRKVPKDEIDERVREVAELLQIEHLLDRKPKQLSGGQRQRVALGRAIVREPKVF 152

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 256041152 155 ILDEPFSGLDpinANL---IKQEIFDLSKN-GTTIIFSTHrmEQVE--EICDRIVLVNQGK 209
Cdd:cd03301  153 LMDEPLSNLD---AKLrvqMRAELKRLQQRlGTTTIYVTH--DQVEamTMADRIAVMNDGQ 208
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
4-211 5.83e-39

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 146.42  E-value: 5.83e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPQtDIHA---IGYMP 80
Cdd:NF033858 267 IEARGLTMRFGDFTAVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAWLFGQPVDAG-DIATrrrVGYMS 345

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  81 EERGLYKKMKVgEQALYL-AQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEP 159
Cdd:NF033858 346 QAFSLYGELTV-RQNLELhARLFHLPAAEIAARVAEMLERFDLADVADALPDSLPLGIRQRLSLAVAVIHKPELLILDEP 424

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 256041152 160 FSGLDPINANLIKQEIFDLSKN-GTTIIFSTHRMEQVEEiCDRIVLVNQGKKL 211
Cdd:NF033858 425 TSGVDPVARDMFWRLLIELSREdGVTIFISTHFMNEAER-CDRISLMHAGRVL 476
ABC_phnC TIGR02315
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of ...
 3-229 7.20e-39

phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of phosphorus-containing organic compound with a stable direct C-P bond rather than a C-O-P linkage. A number of bacterial species have operons, typically about 14 genes in size, with genes for ATP-dependent transport of phosphonates, degradation, and regulation of the expression of the system. Members of this protein family are the ATP-binding cassette component of tripartite ABC transporters of phosphonates. [Transport and binding proteins, Anions]


Pssm-ID: 131368 [Multi-domain]  Cd Length: 243  Bit Score: 137.43  E-value: 7.20e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152    3 LIEIKHLYKHYAT-HKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNG------RPFDPQTDIHA 75
Cdd:TIGR02315   1 MLEVENLSKVYPNgKQALKNINLNINPGEFVAIIGPSGAGKSTLLRCINRLVEPSSGSILLEGtditklRGKKLRKLRRR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   76 IGYMPEERGLYKKMKVGEQAL--------YLAQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTI 147
Cdd:TIGR02315  81 IGMIFQHYNLIERLTVLENVLhgrlgykpTWRSLLGRFSEEDKERALSALERVGLADKAYQRADQLSGGQQQRVAIARAL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  148 MHSPDLLILDEPFSGLDPINANLIKQEIFDLSKN-GTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQIKQDFKQH 226
Cdd:TIGR02315 161 AQQPDLILADEPIASLDPKTSKQVMDYLKRINKEdGITVIINLHQVDLAKKYADRIVGLKAGEIVFDGAPSELDDEVLRH 240


                  ...
gi 256041152  227 LFR 229
Cdd:TIGR02315 241 IYG 243
FtsE COG2884
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
4-209 9.05e-39

Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442130 [Multi-domain]  Cd Length: 223  Bit Score: 136.34  E-value: 9.05e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYAT-HKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFD--PQTDIHA----I 76
Cdd:COG2884    2 IRFENVSKRYPGgREALSDVSLEIEKGEFVFLTGPSGAGKSTLLKLLYGEERPTSGQVLVNGQDLSrlKRREIPYlrrrI 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  77 GYMPEERGLYKKMKVGEQ-ALYLaQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLI 155
Cdd:COG2884   82 GVVFQDFRLLPDRTVYENvALPL-RVTGKSRKEIRRRVREVLDLVGLSDKAKALPHELSGGEQQRVAIARALVNRPELLL 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 256041152 156 LDEPFSGLDPINANLIKQEIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGK 209
Cdd:COG2884  161 ADEPTGNLDPETSWEIMELLEEINRRGTTVLIATHDLELVDRMPKRVLELEDGR 214
PhnC COG3638
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and ...
 3-229 9.06e-39

ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 442855 [Multi-domain]  Cd Length: 249  Bit Score: 137.11  E-value: 9.06e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   3 LIEIKHLYKHYATHK-AVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRpfDPQTDIHA------ 75
Cdd:COG3638    2 MLELRNLSKRYPGGTpALDDVSLEIERGEFVALIGPSGAGKSTLLRCLNGLVEPTSGEILVDGQ--DVTALRGRalrrlr 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  76 --IGYMPEERGLYKKMKVGEQAL-----YLAQLKGM----SERDaKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFI 144
Cdd:COG3638   80 rrIGMIFQQFNLVPRLSVLTNVLagrlgRTSTWRSLlglfPPED-RERALEALERVGLADKAYQRADQLSGGQQQRVAIA 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 145 STIMHSPDLLILDEPFSGLDPINANLIKQEIFDLSK-NGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQIKQDF 223
Cdd:COG3638  159 RALVQEPKLILADEPVASLDPKTARQVMDLLRRIAReDGITVVVNLHQVDLARRYADRIIGLRDGRVVFDGPPAELTDAV 238


                 ....*.
gi 256041152 224 KQHLFR 229
Cdd:COG3638  239 LREIYG 244
ABC_KpsT_Wzt cd03220
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ...
 4-214 3.89e-38

ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.


Pssm-ID: 213187 [Multi-domain]  Cd Length: 224  Bit Score: 134.97  E-value: 3.89e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYAT----------------------HKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEIL 61
Cdd:cd03220    1 IELENVSKSYPTykggssslkklgilgrkgevgeFWALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTVT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  62 FNGR---PFDPQTdihaiGYMPEERGLykkmkvgEQALYLAQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQ 138
Cdd:cd03220   81 VRGRvssLLGLGG-----GFNPELTGR-------ENIYLNGRLLGLSRKEIDEKIDEIIEFSELGDFIDLPVKTYSSGMK 148

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 256041152 139 QKVQFiSTIMHS-PDLLILDEPFSGLDPINANLIKQEIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDG 214
Cdd:cd03220  149 ARLAF-AIATALePDILLIDEVLAVGDAAFQEKCQRRLRELLKQGKTVILVSHDPSSIKRLCDRALVLEKGKIRFDG 224
ABC_PstB_phosphate_transporter cd03260
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ...
 4-219 5.92e-38

ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).


Pssm-ID: 213227 [Multi-domain]  Cd Length: 227  Bit Score: 134.62  E-value: 5.92e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFY-----PDKGEILFNGRpfdpqtDIHAIGY 78
Cdd:cd03260    1 IELRDLNVYYGDKHALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRLNDlipgaPDEGEVLLDGK------DIYDLDV 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  79 MPEERglykKMKVG--------------EQALYLAQLKGMSERDAKDKIKYW-------FDKFEINSwynkKVEELSKGM 137
Cdd:cd03260   75 DVLEL----RRRVGmvfqkpnpfpgsiyDNVAYGLRLHGIKLKEELDERVEEalrkaalWDEVKDRL----HALGLSGGQ 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 138 QQKVQFISTIMHSPDLLILDEPFSGLDPINANLIKQEIFDLSKNgTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVK 217
Cdd:cd03260  147 QQRLCLARALANEPEVLLLDEPTSALDPISTAKIEELIAELKKE-YTIVIVTHNMQQAARVADRTAFLLNGRLVEFGPTE 225


                 ..
gi 256041152 218 QI 219
Cdd:cd03260  226 QI 227
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
 19-161 5.39e-37

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 129.69  E-value: 5.39e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   19 VDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPQTDIHA---IGYMPEERGLYKKMKVGEQA 95
Cdd:pfam00005   1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDDERKSLrkeIGYVFQDPQLFPRLTVRENL 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   96 LYLAQLKGMSERDAKDKIKYWFDKFEINSWYNKKVE----ELSKGMQQKVQFISTIMHSPDLLILDEPFS 161
Cdd:pfam00005  81 RLGLLLKGLSKREKDARAEEALEKLGLGDLADRPVGerpgTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
ABC_CysA_sulfate_importer cd03296
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ...
 4-209 7.11e-37

ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213263 [Multi-domain]  Cd Length: 239  Bit Score: 132.08  E-value: 7.11e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRpfdPQTDIHA----IGYM 79
Cdd:cd03296    3 IEVRNVSKRFGDFVALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFGGE---DATDVPVqernVGFV 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  80 PEERGLYKKMKVGEQALYLAQLKGMSERDAKDKIKY----WFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLI 155
Cdd:cd03296   80 FQHYALFRHMTVFDNVAFGLRVKPRSERPPEAEIRAkvheLLKLVQLDWLADRYPAQLSGGQRQRVALARALAVEPKVLL 159

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 156 LDEPFSGLDpinANLIKQ------EIFDlsKNGTTIIFSTHRMEQVEEICDRIVLVNQGK 209
Cdd:cd03296  160 LDEPFGALD---AKVRKElrrwlrRLHD--ELHVTTVFVTHDQEEALEVADRVVVMNKGR 214
ABC_ModC_molybdenum_transporter cd03297
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ...
 21-209 8.69e-36

ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213264 [Multi-domain]  Cd Length: 214  Bit Score: 128.57  E-value: 8.69e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  21 DISFAIPkGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRP-FDPQTDIH------AIGYMPEERGLYKKMKVGE 93
Cdd:cd03297   16 KIDFDLN-EEVTGIFGASGAGKSTLLRCIAGLEKPDGGTIVLNGTVlFDSRKKINlppqqrKIGLVFQQYALFPHLNVRE 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  94 QALYlaQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEPFSGLDPINANLIKQ 173
Cdd:cd03297   95 NLAF--GLKRKRNREDRISVDELLDLLGLDHLLNRYPAQLSGGEKQRVALARALAAQPELLLLDEPFSALDRALRLQLLP 172

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 256041152 174 EIFDLSKN-GTTIIFSTHRMEQVEEICDRIVLVNQGK 209
Cdd:cd03297  173 ELKQIKKNlNIPVIFVTHDLSEAEYLADRIVVMEDGR 209
LolD COG1136
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
1-209 1.70e-35

ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440751 [Multi-domain]  Cd Length: 227  Bit Score: 128.24  E-value: 1.70e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   1 MN-LIEIKHLYKHY----ATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGrpfdpqTDIHA 75
Cdd:COG1136    1 MSpLLELRNLTKSYgtgeGEVTALRGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVLIDG------QDISS 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  76 IGymPEERGLYKKMKVG---------------EQALYLAQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQK 140
Cdd:COG1136   75 LS--ERELARLRRRHIGfvfqffnllpeltalENVALPLLLAGVSRKERRERARELLERVGLGDRLDHRPSQLSGGQQQR 152

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 141 VQFISTIMHSPDLLILDEPFSGLDPINANLIKQEIFDLSKN-GTTIIFSTHRMEqVEEICDRIVLVNQGK 209
Cdd:COG1136  153 VAIARALVNRPKLILADEPTGNLDSKTGEEVLELLRELNRElGTTIVMVTHDPE-LAARADRVIRLRDGR 221
PRK10895 PRK10895
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
 1-233 2.17e-35

lipopolysaccharide ABC transporter ATP-binding protein; Provisional


Pssm-ID: 182817 [Multi-domain]  Cd Length: 241  Bit Score: 128.47  E-value: 2.17e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   1 MNLIEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNgrpfdpQTDI-----HA 75
Cdd:PRK10895   1 MATLTAKNLAKAYKGRRVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIID------DEDIsllplHA 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  76 -----IGYMPEERGLYKKMKVGEQALYLAQL-KGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMH 149
Cdd:PRK10895  75 rarrgIGYLPQEASIFRRLSVYDNLMAVLQIrDDLSAEQREDRANELMEEFHIEHLRDSMGQSLSGGERRRVEIARALAA 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 150 SPDLLILDEPFSGLDPINANLIKQEIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQIKQDfkQHLFR 229
Cdd:PRK10895 155 NPKFILLDEPFAGVDPISVIDIKRIIEHLRDSGLGVLITDHNVRETLAVCERAYIVSQGHLIAHGTPTEILQD--EHVKR 232


                 ....
gi 256041152 230 IGFG 233
Cdd:PRK10895 233 VYLG 236
livG PRK11300
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
 18-222 2.30e-35

leucine/isoleucine/valine transporter ATP-binding subunit; Provisional


Pssm-ID: 183080 [Multi-domain]  Cd Length: 255  Bit Score: 128.57  E-value: 2.30e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  18 AVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPQTDiHAIGYMPEERG-----LYKKMKVG 92
Cdd:PRK11300  20 AVNNVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTILLRGQHIEGLPG-HQIARMGVVRTfqhvrLFREMTVI 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  93 EQaLYLAQ--------LKGM--------SERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLIL 156
Cdd:PRK11300  99 EN-LLVAQhqqlktglFSGLlktpafrrAESEALDRAATWLERVGLLEHANRQAGNLAYGQQRRLEIARCMVTQPEILML 177

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 256041152 157 DEPFSGLDPINANLIKQEIFDLSKN-GTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQIKQD 222
Cdd:PRK11300 178 DEPAAGLNPKETKELDELIAELRNEhNVTVLLIEHDMKLVMGISDRIYVVNQGTPLANGTPEEIRNN 244
LivF COG0410
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ...
 1-222 2.33e-35

ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];


Pssm-ID: 440179 [Multi-domain]  Cd Length: 236  Bit Score: 127.79  E-value: 2.33e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   1 MNLIEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRpfdpqtDIHA----- 75
Cdd:COG0410    1 MPMLEVENLHAGYGGIHVLHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPRSGSIRFDGE------DITGlpphr 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  76 -----IGYMPEERGLYKKMKVgEQALYLAQLKGMSERDAKDKIKYWFDKFEInswynkkVEE--------LSKGMQQKVQ 142
Cdd:COG0410   75 iarlgIGYVPEGRRIFPSLTV-EENLLLGAYARRDRAEVRADLERVYELFPR-------LKErrrqragtLSGGEQQMLA 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 143 FISTIMHSPDLLILDEPFSGLDPinanLIKQEIFD----LSKNGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQ 218
Cdd:COG0410  147 IGRALMSRPKLLLLDEPSLGLAP----LIVEEIFEiirrLNREGVTILLVEQNARFALEIADRAYVLERGRIVLEGTAAE 222


                 ....
gi 256041152 219 IKQD 222
Cdd:COG0410  223 LLAD 226
ABCC_MRP_Like cd03228
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ...
 4-209 3.75e-35

ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213195 [Multi-domain]  Cd Length: 171  Bit Score: 125.57  E-value: 3.75e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHY--ATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRP---FDPQTDIHAIGY 78
Cdd:cd03228    1 IEFKNVSFSYpgRPKPVLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILIDGVDlrdLDLESLRKNIAY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  79 MPEErglykkmkvgeqalylAQLKGMSERDakdkikywfdkfEInswynkkveeLSKGMQQKVQFISTIMHSPDLLILDE 158
Cdd:cd03228   81 VPQD----------------PFLFSGTIRE------------NI----------LSGGQRQRIAIARALLRDPPILILDE 122

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 256041152 159 PFSGLDPINANLIKQEIFDLSKnGTTIIFSTHRMEQVeEICDRIVLVNQGK 209
Cdd:cd03228  123 ATSALDPETEALILEALRALAK-GKTVIVIAHRLSTI-RDADRIIVLDDGR 171
ABC_HisP_GlnQ cd03262
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ...
 4-209 5.33e-35

ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.


Pssm-ID: 213229 [Multi-domain]  Cd Length: 213  Bit Score: 126.49  E-value: 5.33e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRP-FDPQTDIHAI----GY 78
Cdd:cd03262    1 IEIKNLHKSFGDFHVLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIIDGLKlTDDKKNINELrqkvGM 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  79 MPEERGLYKKMKVGEQ-ALYLAQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILD 157
Cdd:cd03262   81 VFQQFNLFPHLTVLENiTLAPIKVKGMSKAEAEERALELLEKVGLADKADAYPAQLSGGQQQRVAIARALAMNPKVMLFD 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 256041152 158 EPFSGLDPINANLIKQEIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGK 209
Cdd:cd03262  161 EPTSALDPELVGEVLDVMKDLAEEGMTMVVVTHEMGFAREVADRVIFMDDGR 212
ABC_cobalt_CbiO_domain2 cd03226
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ...
 5-209 7.05e-35

Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213193 [Multi-domain]  Cd Length: 205  Bit Score: 125.83  E-value: 7.05e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   5 EIKHL-YKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPQTDIHAIGYMPEE- 82
Cdd:cd03226    1 RIENIsFSYKKGTEILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSGSILLNGKPIKAKERRKSIGYVMQDv 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  83 -RGLYKKmKVGEQALYLAQLKGMSERDAKDKIKywfdKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEPFS 161
Cdd:cd03226   81 dYQLFTD-SVREELLLGLKELDAGNEQAETVLK----DLDLYALKERHPLSLSGGQKQRLAIAAALLSGKDLLIFDEPTS 155

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 256041152 162 GLDPINANLIKQEIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGK 209
Cdd:cd03226  156 GLDYKNMERVGELIRELAAQGKAVIVITHDYEFLAKVCDRVLLLANGA 203
ECF_ATPase_2 TIGR04521
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...
 4-234 1.06e-34

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the downstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 275314 [Multi-domain]  Cd Length: 277  Bit Score: 127.57  E-value: 1.06e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152    4 IEIKHLYKHYAT-----HKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPQTDIHA--- 75
Cdd:TIGR04521   1 IKLKNVSYIYQPgtpfeKKALDDVSLTIEDGEFVAIIGHTGSGKSTLIQHLNGLLKPTSGTVTIDGRDITAKKKKKLkdl 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   76 ---IGY---MPE----ERGLYKKMKVGEQALylaqlkGMSERDAKDKIKYWFDKFEIN-SWYNKKVEELSKGMQQKVQFI 144
Cdd:TIGR04521  81 rkkVGLvfqFPEhqlfEETVYKDIAFGPKNL------GLSEEEAEERVKEALELVGLDeEYLERSPFELSGGQMRRVAIA 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  145 STIMHSPDLLILDEPFSGLDPINanliKQEIFDL-----SKNGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQI 219
Cdd:TIGR04521 155 GVLAMEPEVLILDEPTAGLDPKG----RKEILDLfkrlhKEKGLTVILVTHSMEDVAEYADRVIVMHKGKIVLDGTPREV 230

                         250
                  ....*....|....*
gi 256041152  220 KQDfKQHLFRIGFGV 234
Cdd:TIGR04521 231 FSD-VDELEKIGLDV 244
GlnQ COG1126
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ...
 3-219 3.76e-34

ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440743 [Multi-domain]  Cd Length: 239  Bit Score: 124.72  E-value: 3.76e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   3 LIEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPF-DPQTDIHA----IG 77
Cdd:COG1126    1 MIEIENLHKSFGDLEVLKGISLDVEKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTITVDGEDLtDSKKDINKlrrkVG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  78 YMPEERGLYKKMKVGEQ-ALYLAQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLIL 156
Cdd:COG1126   81 MVFQQFNLFPHLTVLENvTLAPIKVKKMSKAEAEERAMELLERVGLADKADAYPAQLSGGQQQRVAIARALAMEPKVMLF 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 256041152 157 DEPFSGLDPINA----NLIKqeifDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQI 219
Cdd:COG1126  161 DEPTSALDPELVgevlDVMR----DLAKEGMTMVVVTHEMGFAREVADRVVFMDGGRIVEEGPPEEF 223
ABC_MetN_methionine_transporter cd03258
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ...
 3-219 2.14e-33

ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213225 [Multi-domain]  Cd Length: 233  Bit Score: 122.69  E-value: 2.14e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   3 LIEIKHLYKHYATH----KAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGR------PFDPQTD 72
Cdd:cd03258    1 MIELKNVSKVFGDTggkvTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLVDGTdltllsGKELRKA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  73 IHAIGYMPEERGLYKKMKVGEQALYLAQLKGMSERDAKDKIKywfDKFEINSWYNKK---VEELSKGMQQKVQFISTIMH 149
Cdd:cd03258   81 RRRIGMIFQHFNLLSSRTVFENVALPLEIAGVPKAEIEERVL---ELLELVGLEDKAdayPAQLSGGQKQRVGIARALAN 157

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 256041152 150 SPDLLILDEPFSGLDPINAnlikQEIFDLSKN-----GTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQI 219
Cdd:cd03258  158 NPKVLLCDEATSALDPETT----QSILALLRDinrelGLTIVLITHEMEVVKRICDRVAVMEKGEVVEEGTVEEV 228
DppD COG0444
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
 3-203 3.58e-33

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440213 [Multi-domain]  Cd Length: 320  Bit Score: 124.40  E-value: 3.58e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   3 LIEIKHLYKHYATH----KAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYP---DKGEILFNGRpfdpqtDIHA 75
Cdd:COG0444    1 LLEVRNLKVYFPTRrgvvKAVDGVSFDVRRGETLGLVGESGSGKSTLARAILGLLPPpgiTSGEILFDGE------DLLK 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  76 igyMPEE--RGLYKK----------------MKVGEQ-ALYLAQLKGMSERDAKDKIKYWFDKFEIN---SWYNKKVEEL 133
Cdd:COG0444   75 ---LSEKelRKIRGReiqmifqdpmtslnpvMTVGDQiAEPLRIHGGLSKAEARERAIELLERVGLPdpeRRLDRYPHEL 151

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 256041152 134 SKGMQQKVQFISTIMHSPDLLILDEPFSGLDPInanlIKQEIFDL-----SKNGTTIIFSTHRMEQVEEICDRIV 203
Cdd:COG0444  152 SGGMRQRVMIARALALEPKLLIADEPTTALDVT----IQAQILNLlkdlqRELGLAILFITHDLGVVAEIADRVA 222
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
3-209 9.12e-33

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 126.67  E-value: 9.12e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   3 LIEIKHLykhyATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPQTDIHA----IGY 78
Cdd:COG1129  256 VLEVEGL----SVGGVVRDVSFSVRAGEILGIAGLVGAGRTELARALFGADPADSGEIRLDGKPVRIRSPRDAiragIAY 331

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  79 MPEER---GLYKKMKVGEQaLYLAQLKG------MSERDAKDKIKYWFDKFEI--NSWyNKKVEELSKGMQQKVQFISTI 147
Cdd:COG1129  332 VPEDRkgeGLVLDLSIREN-ITLASLDRlsrgglLDRRRERALAEEYIKRLRIktPSP-EQPVGNLSGGNQQKVVLAKWL 409

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 256041152 148 MHSPDLLILDEPFSGLDpINAnliKQEIF----DLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGK 209
Cdd:COG1129  410 ATDPKVLILDEPTRGID-VGA---KAEIYrlirELAAEGKAVIVISSELPELLGLSDRILVMREGR 471
AbcC COG1135
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
4-281 2.22e-32

ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440750 [Multi-domain]  Cd Length: 339  Bit Score: 122.88  E-value: 2.22e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYAT----HKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRpfdpqtDIHAIgym 79
Cdd:COG1135    2 IELENLSKTFPTkggpVTALDDVSLTIEKGEIFGIIGYSGAGKSTLIRCINLLERPTSGSVLVDGV------DLTAL--- 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  80 peerglykkmkvGEQALYLAQLK-GM--------SERDAKDKI----KYW-FDKFEInswyNKKVEE------------- 132
Cdd:COG1135   73 ------------SERELRAARRKiGMifqhfnllSSRTVAENValplEIAgVPKAEI----RKRVAEllelvglsdkada 136

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 133 ----LSKGMQQKVQfistI----MHSPDLLILDEPFSGLDPINAnlikQEIFDLSKN-----GTTIIFSTHRMEQVEEIC 199
Cdd:COG1135  137 ypsqLSGGQKQRVG----IaralANNPKVLLCDEATSALDPETT----RSILDLLKDinrelGLTIVLITHEMDVVRRIC 208

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 200 DRIVLVNQGKKLLDGEVKQI----KQDFKQHLFRIGFGVMPNfAQVATHHFSIIKQEPLaYTVKLTEGSTNNDILAHFIR 275
Cdd:COG1135  209 DRVAVLENGRIVEQGPVLDVfanpQSELTRRFLPTVLNDELP-EELLARLREAAGGGRL-VRLTFVGESADEPLLSELAR 286


                 ....*..
gi 256041152 276 -HNVPIT 281
Cdd:COG1135  287 rFGVDVN 293
ABC_Pro_Gly_Betaine cd03294
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ...
 4-219 6.48e-32

ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213261 [Multi-domain]  Cd Length: 269  Bit Score: 120.06  E-value: 6.48e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYATHK------------------------AVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGE 59
Cdd:cd03294    1 IKIKGLYKIFGKNPqkafkllakgkskeeilkktgqtvGVNDVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIEPTSGK 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  60 ILFNGRPFDPQTDI-------HAIGYMPEERGLYKKMKVGEQALYLAQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEE 132
Cdd:cd03294   81 VLIDGQDIAAMSRKelrelrrKKISMVFQSFALLPHRTVLENVAFGLEVQGVPRAEREERAAEALELVGLEGWEHKYPDE 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 133 LSKGMQQKVQFISTIMHSPDLLILDEPFSGLDPinanLIKQEIFDL-----SKNGTTIIFSTHRMEQVEEICDRIVLVNq 207
Cdd:cd03294  161 LSGGMQQRVGLARALAVDPDILLMDEAFSALDP----LIRREMQDEllrlqAELQKTIVFITHDLDEALRLGDRIAIMK- 235

                        250
                 ....*....|..
gi 256041152 208 gkkllDGEVKQI 219
Cdd:cd03294  236 -----DGRLVQV 242
ABC_ModC_like cd03299
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ...
 4-219 8.71e-32

ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213266 [Multi-domain]  Cd Length: 235  Bit Score: 118.59  E-value: 8.71e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYATHKaVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGR---PFDPqtDIHAIGYMP 80
Cdd:cd03299    1 LKVENLSKDWKEFK-LKNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKILLNGKditNLPP--EKRDISYVP 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  81 EERGLYKKMKVGEQALYLAQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEPF 160
Cdd:cd03299   78 QNYALFPHMTVYKNIAYGLKKRKVDKKEIERKVLEIAEMLGIDHLLNRKPETLSGGEQQRVAIARALVVNPKILLLDEPF 157

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 161 SGLDP-INANLIKQEIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQI 219
Cdd:cd03299  158 SALDVrTKEKLREELKKIRKEFGVTVLHVTHDFEEAWALADKVAIMLNGKLIQVGKPEEV 217
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
 18-214 2.23e-31

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 124.36  E-value: 2.23e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152    18 AVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPQTDI--HAIGYMPEERGLYKKMKVGEQA 95
Cdd:TIGR01257  945 AVDRLNITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGKDIETNLDAvrQSLGMCPQHNILFHHLTVAEHI 1024

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152    96 LYLAQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEPFSGLDPINanliKQEI 175
Cdd:TIGR01257 1025 LFYAQLKGRSWEEAQLEMEAMLEDTGLHHKRNEEAQDLSGGMQRKLSVAIAFVGDAKVVVLDEPTSGVDPYS----RRSI 1100

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|..
gi 256041152   176 FDL---SKNGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDG 214
Cdd:TIGR01257 1101 WDLllkYRSGRTIIMSTHHMDEADLLGDRIAIISQGRLYCSG 1142
ABCG_EPDR cd03213
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ...
 19-209 2.32e-31

Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.


Pssm-ID: 213180 [Multi-domain]  Cd Length: 194  Bit Score: 116.11  E-value: 2.32e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  19 VDDISFAIPKGSIFGLLGPNGAGKTTLLRMITG--IFYPDKGEILFNGRPFDPQTDIHAIGYMPEERGLYKKMKVGEQAL 96
Cdd:cd03213   25 LKNVSGKAKPGELTAIMGPSGAGKSTLLNALAGrrTGLGVSGEVLINGRPLDKRSFRKIIGYVPQDDILHPTLTVRETLM 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  97 YLAQLKGMS--ERdakdkikywfdkfeinswynKKVeelSKGMQqkvqfistIMHSPDLLILDEPFSGLDPINANLIKQE 174
Cdd:cd03213  105 FAAKLRGLSggER--------------------KRV---SIALE--------LVSNPSLLFLDEPTSGLDSSSALQVMSL 153

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 256041152 175 IFDLSKNGTTIIFSTHRM-EQVEEICDRIVLVNQGK 209
Cdd:cd03213  154 LRRLADTGRTIICSIHQPsSEIFELFDKLLLLSQGR 189
potG PRK11607
putrescine ABC transporter ATP-binding subunit PotG;
3-219 3.94e-31

putrescine ABC transporter ATP-binding subunit PotG;


Pssm-ID: 183226 [Multi-domain]  Cd Length: 377  Bit Score: 120.33  E-value: 3.94e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   3 LIEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNG----------RPfdpqtd 72
Cdd:PRK11607  19 LLEIRNLTKSFDGQHAVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIMLDGvdlshvppyqRP------ 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  73 ihaIGYMPEERGLYKKMKVgEQ--ALYLAQLKgMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHS 150
Cdd:PRK11607  93 ---INMMFQSYALFPHMTV-EQniAFGLKQDK-LPKAEIASRVNEMLGLVHMQEFAKRKPHQLSGGQRQRVALARSLAKR 167

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 151 PDLLILDEPFSGLDPINANLIKQEIFD-LSKNGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQI 219
Cdd:PRK11607 168 PKLLLLDEPMGALDKKLRDRMQLEVVDiLERVGVTCVMVTHDQEEAMTMAGRIAIMNRGKFVQIGEPEEI 237
SunT COG2274
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ...
 4-214 8.58e-31

ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];


Pssm-ID: 441875 [Multi-domain]  Cd Length: 711  Bit Score: 122.25  E-value: 8.58e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYATHK--AVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRP---FDPQTDIHAIGY 78
Cdd:COG2274  474 IELENVSFRYPGDSppVLDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEPTSGRILIDGIDlrqIDPASLRRQIGV 553

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  79 MPEERGLYKkmkvG---------------EQALYLAQLKGMSErdakdkikywfdkfEINSW---YNKKVEE----LSKG 136
Cdd:COG2274  554 VLQDVFLFS----GtirenitlgdpdatdEEIIEAARLAGLHD--------------FIEALpmgYDTVVGEggsnLSGG 615

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 256041152 137 MQQKVQFISTIMHSPDLLILDEPFSGLDPINANLIKQEIFDLSKnGTTIIFSTHRMEQVeEICDRIVLVNQGKKLLDG 214
Cdd:COG2274  616 QRQRLAIARALLRNPRILILDEATSALDAETEAIILENLRRLLK-GRTVIIIAHRLSTI-RLADRIIVLDKGRIVEDG 691
cbiO PRK13636
cobalt transporter ATP-binding subunit; Provisional
 2-219 1.03e-30

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184196 [Multi-domain]  Cd Length: 283  Bit Score: 117.26  E-value: 1.03e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   2 NLIEIKHLYKHYA--THkAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDpqtdIHAIGYM 79
Cdd:PRK13636   4 YILKVEELNYNYSdgTH-ALKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRILFDGKPID----YSRKGLM 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  80 PEERGLYKKMKVGEQALYLAQLK----------GMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMH 149
Cdd:PRK13636  79 KLRESVGMVFQDPDNQLFSASVYqdvsfgavnlKLPEDEVRKRVDNALKRTGIEHLKDKPTHCLSFGQKKRVAIAGVLVM 158

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 256041152 150 SPDLLILDEPFSGLDPINANLIKQEIFDLSKN-GTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQI 219
Cdd:PRK13636 159 EPKVLVLDEPTAGLDPMGVSEIMKLLVEMQKElGLTIIIATHDIDIVPLYCDNVFVMKEGRVILQGNPKEV 229
ModF COG1119
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ...
 1-219 1.78e-30

ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];


Pssm-ID: 440736 [Multi-domain]  Cd Length: 250  Bit Score: 115.57  E-value: 1.78e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   1 MNLIEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGE--ILFnGRPFDpQTDIHA--- 75
Cdd:COG1119    1 DPLLELRNVTVRRGGKTILDDISWTVKPGEHWAILGPNGAGKSTLLSLITGDLPPTYGNdvRLF-GERRG-GEDVWElrk 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  76 -IG---------YMPEER-------------GLYKKmkvgeqalYlaqlkgmSERDaKDKIKYWFDKFEINSWYNKKVEE 132
Cdd:COG1119   79 rIGlvspalqlrFPRDETvldvvlsgffdsiGLYRE--------P-------TDEQ-RERARELLELLGLAHLADRPFGT 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 133 LSKGMQQKVQFISTIMHSPDLLILDEPFSGLDPINANLIKQEIFDLSKNG-TTIIFSTHRMEQV-EEIcDRIVLVNQGKK 210
Cdd:COG1119  143 LSQGEQRRVLIARALVKDPELLILDEPTAGLDLGARELLLALLDKLAAEGaPTLVLVTHHVEEIpPGI-THVLLLKDGRV 221


                 ....*....
gi 256041152 211 LLDGEVKQI 219
Cdd:COG1119  222 VAAGPKEEV 230
ABC_Carb_Monos_II cd03215
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ...
 5-209 2.44e-30

Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213182 [Multi-domain]  Cd Length: 182  Bit Score: 113.30  E-value: 2.44e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   5 EIKHLykhyATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPQTDIHA----IGYMP 80
Cdd:cd03215    6 EVRGL----SVKGAVRDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGEITLDGKPVTRRSPRDAiragIAYVP 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  81 EER---GLYKKMKVGEQALyLAQLkgmserdakdkikywfdkfeinswynkkveeLSKGMQQKVQFISTIMHSPDLLILD 157
Cdd:cd03215   82 EDRkreGLVLDLSVAENIA-LSSL-------------------------------LSGGNQQKVVLARWLARDPRVLILD 129

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 256041152 158 EPFSGLDPINANLIKQEIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGK 209
Cdd:cd03215  130 EPTRGVDVGAKAEIYRLIRELADAGKAVLLISSELDELLGLCDRILVMYEGR 181
ABC_FtsE cd03292
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ...
 4-209 1.80e-29

Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages


Pssm-ID: 213259 [Multi-domain]  Cd Length: 214  Bit Score: 111.73  E-value: 1.80e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHY-ATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFdpqTDIH-------- 74
Cdd:cd03292    1 IEFINVTKTYpNGTAALDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVNGQDV---SDLRgraipylr 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  75 -AIGYMPEERGLYKKMKVGEQALYLAQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDL 153
Cdd:cd03292   78 rKIGVVFQDFRLLPDRNVYENVAFALEVTGVPPREIRKRVPAALELVGLSHKHRALPAELSGGEQQRVAIARAIVNSPTI 157

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 256041152 154 LILDEPFSGLDPINANLIKQEIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGK 209
Cdd:cd03292  158 LIADEPTGNLDPDTTWEIMNLLKKINKAGTTVVVATHAKELVDTTRHRVIALERGK 213
ArtP COG4161
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
4-209 1.20e-28

ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443326 [Multi-domain]  Cd Length: 242  Bit Score: 110.49  E-value: 1.20e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPQTDIHA-------- 75
Cdd:COG4161    3 IQLKNINCFYGSHQALFDINLECPSGETLVLLGPSGAGKSSLLRVLNLLETPDSGQLNIAGHQFDFSQKPSEkairllrq 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  76 -IGYMPEERGLYKKMKVgEQALYLAQLK--GMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPD 152
Cdd:COG4161   83 kVGMVFQQYNLWPHLTV-MENLIEAPCKvlGLSKEQAREKAMKLLARLRLTDKADRFPLHLSGGQQQRVAIARALMMEPQ 161

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 256041152 153 LLILDEPFSGLDPINANLIKQEIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGK 209
Cdd:COG4161  162 VLLFDEPTAALDPEITAQVVEIIRELSQTGITQVIVTHEVEFARKVASQVVYMEKGR 218
cbiO PRK13639
cobalt transporter ATP-binding subunit; Provisional
 3-222 9.34e-28

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184199 [Multi-domain]  Cd Length: 275  Bit Score: 109.01  E-value: 9.34e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   3 LIEIKHL-YKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPfdpqtdihaIGYmpE 81
Cdd:PRK13639   1 ILETRDLkYSYPDGTEALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEVLIKGEP---------IKY--D 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  82 ERGLYK-KMKVG---------------EQALYLAQLK-GMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFI 144
Cdd:PRK13639  70 KKSLLEvRKTVGivfqnpddqlfaptvEEDVAFGPLNlGLSKEEVEKRVKEALKAVGMEGFENKPPHHLSGGQKKRVAIA 149

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 256041152 145 STIMHSPDLLILDEPFSGLDPINANLIKQEIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQIKQD 222
Cdd:PRK13639 150 GILAMKPEIIVLDEPTSGLDPMGASQIMKLLYDLNKEGITIIISTHDVDLVPVYADKVYVMSDGKIIKEGTPKEVFSD 227
potA PRK09452
spermidine/putrescine ABC transporter ATP-binding protein PotA;
1-219 9.43e-28

spermidine/putrescine ABC transporter ATP-binding protein PotA;


Pssm-ID: 236523 [Multi-domain]  Cd Length: 375  Bit Score: 110.81  E-value: 9.43e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   1 MNLIEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRpfdpqtDIHAIGymP 80
Cdd:PRK09452  12 SPLVELRGISKSFDGKEVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIMLDGQ------DITHVP--A 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  81 EER-----------------------GLykKM-KVGEQ--------ALYLAQLKGMSERdakdkikywfdkfeinswynk 128
Cdd:PRK09452  84 ENRhvntvfqsyalfphmtvfenvafGL--RMqKTPAAeitprvmeALRMVQLEEFAQR--------------------- 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 129 KVEELSKGMQQKVQFISTIMHSPDLLILDEPFSGLDpinANLIKQ---EIFDLSKN-GTTIIFSTHRMEQVEEICDRIVL 204
Cdd:PRK09452 141 KPHQLSGGQQQRVAIARAVVNKPKVLLLDESLSALD---YKLRKQmqnELKALQRKlGITFVFVTHDQEEALTMSDRIVV 217

                        250
                 ....*....|....*
gi 256041152 205 VNQGKKLLDGEVKQI 219
Cdd:PRK09452 218 MRDGRIEQDGTPREI 232
glnQ PRK09493
glutamine ABC transporter ATP-binding protein GlnQ;
3-226 1.46e-27

glutamine ABC transporter ATP-binding protein GlnQ;


Pssm-ID: 181906 [Multi-domain]  Cd Length: 240  Bit Score: 107.49  E-value: 1.46e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   3 LIEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPF-DPQTDIHAI----G 77
Cdd:PRK09493   1 MIEFKNVSKHFGPTQVLHNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITSGDLIVDGLKVnDPKVDERLIrqeaG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  78 YMPEERGLYKKMKVGEQALY-LAQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLIL 156
Cdd:PRK09493  81 MVFQQFYLFPHLTALENVMFgPLRVRGASKEEAEKQARELLAKVGLAERAHHYPSELSGGQQQRVAIARALAVKPKLMLF 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 157 DEPFSGLDPinanLIKQEIF----DLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQI--------KQDFK 224
Cdd:PRK09493 161 DEPTSALDP----ELRHEVLkvmqDLAEEGMTMVIVTHEIGFAEKVASRLIFIDKGRIAEDGDPQVLiknppsqrLQEFL 236


                 ..
gi 256041152 225 QH 226
Cdd:PRK09493 237 QH 238
cbiO PRK13637
energy-coupling factor transporter ATPase;
17-234 7.88e-27

energy-coupling factor transporter ATPase;


Pssm-ID: 237455 [Multi-domain]  Cd Length: 287  Bit Score: 106.67  E-value: 7.88e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  17 KAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGrpFDPQ------TDIHA-IGYM---PE----E 82
Cdd:PRK13637  21 KALDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIIIDG--VDITdkkvklSDIRKkVGLVfqyPEyqlfE 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  83 RGLYKKMKVGEQALylaqlkGMSERDAKDKIKYWFD--KFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEPF 160
Cdd:PRK13637  99 ETIEKDIAFGPINL------GLSEEEIENRVKRAMNivGLDYEDYKDKSPFELSGGQKRRVAIAGVVAMEPKILILDEPT 172

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 256041152 161 SGLDPINANLIKQEIFDLSKN-GTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQIkqdFKQ--HLFRIGFGV 234
Cdd:PRK13637 173 AGLDPKGRDEILNKIKELHKEyNMTIILVSHSMEDVAKLADRIIVMNKGKCELQGTPREV---FKEveTLESIGLAV 246
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
 3-219 1.69e-26

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 109.12  E-value: 1.69e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152    3 LIEIKHLYKHYATH-----KAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFngRPFDPQTDI---- 73
Cdd:TIGR03269 279 IIKVRNVSKRYISVdrgvvKAVDNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGEVNV--RVGDEWVDMtkpg 356

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   74 --------HAIGYMPEERGLYKKMKVGE---QALYLAQLKGMSERDAKDKIK-YWFDKFEINSWYNKKVEELSKGMQQKV 141
Cdd:TIGR03269 357 pdgrgrakRYIGILHQEYDLYPHRTVLDnltEAIGLELPDELARMKAVITLKmVGFDEEKAEEILDKYPDELSEGERHRV 436

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 256041152  142 QFISTIMHSPDLLILDEPFSGLDPINANLIKQEIFDLSKN-GTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQI 219
Cdd:TIGR03269 437 ALAQVLIKEPRIVILDEPTGTMDPITKVDVTHSILKAREEmEQTFIIVSHDMDFVLDVCDRAALMRDGKIVKIGDPEEI 515
CydD COG4988
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ...
 4-209 2.10e-26

ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444012 [Multi-domain]  Cd Length: 563  Bit Score: 109.08  E-value: 2.10e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHL-YKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRP---FDPQTDIHAIGYM 79
Cdd:COG4988  337 IELEDVsFSYPGGRPALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPYSGSILINGVDlsdLDPASWRRQIAWV 416

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  80 PeerglykkmkvgeQALYLaqLKG-------MSERDA-KDKIKYWFDKFEINSW-------YNKKVEE----LSKGMQQK 140
Cdd:COG4988  417 P-------------QNPYL--FAGtirenlrLGRPDAsDEELEAALEAAGLDEFvaalpdgLDTPLGEggrgLSGGQAQR 481

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 256041152 141 VQFISTIMHSPDLLILDEPFSGLDPINANLIKQEIFDLSKnGTTIIFSTHRMEQVEEiCDRIVLVNQGK 209
Cdd:COG4988  482 LALARALLRDAPLLLLDEPTAHLDAETEAEILQALRRLAK-GRTVILITHRLALLAQ-ADRILVLDDGR 548
ThiQ COG3840
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
2-219 6.42e-26

ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];


Pssm-ID: 443051 [Multi-domain]  Cd Length: 232  Bit Score: 102.91  E-value: 6.42e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   2 NLIEIKHLYKHYATHkavddISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPQTdihaigymPE 81
Cdd:COG3840    3 RLDDLTYRYGDFPLR-----FDLTIAAGERVAILGPSGAGKSTLLNLIAGFLPPDSGRILWNGQDLTALP--------PA 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  82 ERG---------LYKKMKVgEQALYLaqlkGMS-----ERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTI 147
Cdd:COG3840   70 ERPvsmlfqennLFPHLTV-AQNIGL----GLRpglklTAEQRAQVEQALERVGLAGLLDRLPGQLSGGQRQRVALARCL 144

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 256041152 148 MHSPDLLILDEPFSGLDPinaNLiKQEIFDLSKN-----GTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQI 219
Cdd:COG3840  145 VRKRPILLLDEPFSALDP---AL-RQEMLDLVDElcrerGLTVLMVTHDPEDAARIADRVLLVADGRIAADGPTAAL 217
CydC COG4987
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ...
 4-209 1.06e-25

ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444011 [Multi-domain]  Cd Length: 569  Bit Score: 107.16  E-value: 1.06e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHY--ATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFD--PQTDIHA-IGY 78
Cdd:COG4987  334 LELEDVSFRYpgAGRPVLDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDPQSGSITLGGVDLRdlDEDDLRRrIAV 413

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  79 MPEE--------RG--LYKKMKVGE----QALYLAQLKGmserdakdkikyWFDKFE--INSWynkkVEE----LSKGMQ 138
Cdd:COG4987  414 VPQRphlfdttlREnlRLARPDATDeelwAALERVGLGD------------WLAALPdgLDTW----LGEggrrLSGGER 477

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 256041152 139 QKVQFISTIMHSPDLLILDEPFSGLDPINANLIKQEIFDLSKnGTTIIFSTHRMEQVEEiCDRIVLVNQGK 209
Cdd:COG4987  478 RRLALARALLRDAPILLLDEPTEGLDAATEQALLADLLEALA-GRTVLLITHRLAGLER-MDRILVLEDGR 546
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
 3-222 1.32e-25

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 106.67  E-value: 1.32e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   3 LIEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPQTDIHA----IGY 78
Cdd:PRK15439  11 LLCARSISKQYSGVEVLKGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGTLEIGGNPCARLTPAKAhqlgIYL 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  79 MPEERGLYKKMKVGEQALYLAQLKGMSERDAKDKIKywfdkfEINSWYNKKVE--ELSKGMQQKVQFISTIMHSPDLLIL 156
Cdd:PRK15439  91 VPQEPLLFPNLSVKENILFGLPKRQASMQKMKQLLA------ALGCQLDLDSSagSLEVADRQIVEILRGLMRDSRILIL 164

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 256041152 157 DEPFSGLDPINANLIKQEIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQIKQD 222
Cdd:PRK15439 165 DEPTASLTPAETERLFSRIRELLAQGVGIVFISHKLPEIRQLADRISVMRDGTIALSGKTADLSTD 230
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
11-210 1.33e-25

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 106.53  E-value: 1.33e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  11 KHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRP--FDPQTD-IHA-IGYMPEERGLY 86
Cdd:PRK11288  12 KTFPGVKALDDISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGSILIDGQEmrFASTTAaLAAgVAIIYQELHLV 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  87 KKMKVGEQaLYLAQL--------KGMSERDAKDKIKYWFDKFEINSwynkKVEELSKGMQQKVQFISTIMHSPDLLILDE 158
Cdd:PRK11288  92 PEMTVAEN-LYLGQLphkggivnRRLLNYEAREQLEHLGVDIDPDT----PLKYLSIGQRQMVEIAKALARNARVIAFDE 166

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 256041152 159 PFSGLDPINANLIKQEIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGKK 210
Cdd:PRK11288 167 PTSSLSAREIEQLFRVIRELRAEGRVILYVSHRMEEIFALCDAITVFKDGRY 218
fbpC PRK11432
ferric ABC transporter ATP-binding protein;
2-209 2.19e-25

ferric ABC transporter ATP-binding protein;


Pssm-ID: 183133 [Multi-domain]  Cd Length: 351  Bit Score: 104.03  E-value: 2.19e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   2 NLIEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFD----PQTDIHAI- 76
Cdd:PRK11432   5 NFVVLKNITKRFGSNTVIDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQIFIDGEDVThrsiQQRDICMVf 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  77 -GYmpeerGLYKKMKVGEQALYLAQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLI 155
Cdd:PRK11432  85 qSY-----ALFPHMSLGENVGYGLKMLGVPKEERKQRVKEALELVDLAGFEDRYVDQISGGQQQRVALARALILKPKVLL 159

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 256041152 156 LDEPFSGLDpinANL---IKQEIFDLSKN-GTTIIFSTHRMEQVEEICDRIVLVNQGK 209
Cdd:PRK11432 160 FDEPLSNLD---ANLrrsMREKIRELQQQfNITSLYVTHDQSEAFAVSDTVIVMNKGK 214
cbiO TIGR01166
cobalt transport protein ATP-binding subunit; This model describes the ATP binding subunit of ...
 17-190 2.45e-25

cobalt transport protein ATP-binding subunit; This model describes the ATP binding subunit of the multisubunit cobalt transporter in bacteria and its equivalents in archaea. The model is restricted to ATP subunit that is a part of the cobalt transporter, which belongs to the ABC transporter superfamily (ATP Binding Cassette). The model excludes ATP binding subunit that are associated with other transporters belonging to ABC transporter superfamily. This superfamily includes two groups, one which catalyze the uptake of small molecules, including ions from the external milieu and the other group which is engaged in the efflux of small molecular weight compounds and ions from within the cell. Energy derived from the hydrolysis of ATP drive the both the process of uptake and efflux. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 130234 [Multi-domain]  Cd Length: 190  Bit Score: 100.19  E-value: 2.45e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   17 KAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDpqtdihaigYmpEERGLYK-KMKVG--- 92
Cdd:TIGR01166   6 EVLKGLNFAAERGEVLALLGANGAGKSTLLLHLNGLLRPQSGAVLIDGEPLD---------Y--SRKGLLErRQRVGlvf 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   93 ---EQALYLAQLK----------GMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEP 159
Cdd:TIGR01166  75 qdpDDQLFAADVDqdvafgplnlGLSEAEVERRVREALTAVGASGLRERPTHCLSGGEKKRVAIAGAVAMRPDVLLLDEP 154

                         170       180       190
                  ....*....|....*....|....*....|.
gi 256041152  160 FSGLDPINANLIKQEIFDLSKNGTTIIFSTH 190
Cdd:TIGR01166 155 TAGLDPAGREQMLAILRRLRAEGMTVVISTH 185
cbiO PRK13647
cobalt transporter ATP-binding subunit; Provisional
 2-216 2.70e-25

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237457 [Multi-domain]  Cd Length: 274  Bit Score: 102.12  E-value: 2.70e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   2 NLIEIKHLYKHYAT-HKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPQTdihaigymp 80
Cdd:PRK13647   3 NIIEVEDLHFRYKDgTKALKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGRVKVMGREVNAEN--------- 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  81 eERGLYKK--------------MKVGEQALYLAQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFIST 146
Cdd:PRK13647  74 -EKWVRSKvglvfqdpddqvfsSTVWDDVAFGPVNMGLDKDEVERRVEEALKAVRMWDFRDKPPYHLSYGQKKRVAIAGV 152

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 147 IMHSPDLLILDEPFSGLDPINANLIKQEIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEV 216
Cdd:PRK13647 153 LAMDPDVIVLDEPMAYLDPRGQETLMEILDRLHNQGKTVIVATHDVDLAAEWADQVIVLKEGRVLAEGDK 222
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
2-220 3.16e-25

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 103.66  E-value: 3.16e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   2 NLIEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAG--KTTLLRMITGifyPDKGEilfngRPF-------DPQTD 72
Cdd:NF000106  12 NAVEVRGLVKHFGEVKAVDGVDLDVREGTVLGVLGP*GAA**RGALPAHV*G---PDAGR-----RPWrf*twcaNRRAL 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  73 IHAIGYMPEERGLYKKMKVGEQALYL-AQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSP 151
Cdd:NF000106  84 RRTIG*HRPVR*GRRESFSGRENLYMiGR*LDLSRKDARARADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRP 163

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 256041152 152 DLLILDEPFSGLDPINANLIKQEIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQIK 220
Cdd:NF000106 164 AVLYLDEPTTGLDPRTRNEVWDEVRSMVRDGATVLLTTQYMEEAEQLAHELTVIDRGRVIADGKVDELK 232
hmuV PRK13548
hemin importer ATP-binding subunit; Provisional
 3-214 3.62e-25

hemin importer ATP-binding subunit; Provisional


Pssm-ID: 237422 [Multi-domain]  Cd Length: 258  Bit Score: 101.39  E-value: 3.62e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   3 LIEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFD-------------- 68
Cdd:PRK13548   2 MLEARNLSVRLGGRTLLDDVSLTLRPGEVVAILGPNGAGKSTLLRALSGELSPDSGEVRLNGRPLAdwspaelarrravl 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  69 PQ----------TDIHAIGYMPEERGLYKKMKVGEQALYLAQLKGMSERDakdkikYwfdkfeinswynkkvEELSKGMQ 138
Cdd:PRK13548  82 PQhsslsfpftvEEVVAMGRAPHGLSRAEDDALVAAALAQVDLAHLAGRD------Y---------------PQLSGGEQ 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 139 QKVQF------ISTIMHSPDLLILDEPFSGLDPINanliKQEIFDLSKN-----GTTIIFSTHRMEQVEEICDRIVLVNQ 207
Cdd:PRK13548 141 QRVQLarvlaqLWEPDGPPRWLLLDEPTSALDLAH----QHHVLRLARQlaherGLAVIVVLHDLNLAARYADRIVLLHQ 216


                 ....*..
gi 256041152 208 GKKLLDG 214
Cdd:PRK13548 217 GRLVADG 223
PRK09984 PRK09984
phosphonate ABC transporter ATP-binding protein;
3-229 4.03e-25

phosphonate ABC transporter ATP-binding protein;


Pssm-ID: 182182 [Multi-domain]  Cd Length: 262  Bit Score: 101.63  E-value: 4.03e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   3 LIEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKG-----EILFN-----GR-PFDPQT 71
Cdd:PRK09984   4 IIRVEKLAKTFNQHQALHAVDLNIHHGEMVALLGPSGSGKSTLLRHLSGLITGDKSagshiELLGRtvqreGRlARDIRK 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  72 DIHAIGYMPEERGLYKKMKVGEQALYLAQ---------LKGMSeRDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQ 142
Cdd:PRK09984  84 SRANTGYIFQQFNLVNRLSVLENVLIGALgstpfwrtcFSWFT-REQKQRALQALTRVGMVHFAHQRVSTLSGGQQQRVA 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 143 FISTIMHSPDLLILDEPFSGLDPINANLIKQEIFDLSKN-GTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQIKQ 221
Cdd:PRK09984 163 IARALMQQAKVILADEPIASLDPESARIVMDTLRDINQNdGITVVVTLHQVDYALRYCERIVALRQGHVFYDGSSQQFDN 242


                 ....*...
gi 256041152 222 DFKQHLFR 229
Cdd:PRK09984 243 ERFDHLYR 250
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
3-222 4.18e-25

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 105.25  E-value: 4.18e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   3 LIEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPQTDIHA----IGY 78
Cdd:PRK09700   5 YISMAGIGKSFGPVHALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNINYNKLDHKLAaqlgIGI 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  79 MPEERGLYKKMKVGEQaLYLAQL-------------KGMSERDAKdkikyWFDKFEINSWYNKKVEELSKGMQQKVQFIS 145
Cdd:PRK09700  85 IYQELSVIDELTVLEN-LYIGRHltkkvcgvniidwREMRVRAAM-----MLLRVGLKVDLDEKVANLSISHKQMLEIAK 158

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 256041152 146 TIMHSPDLLILDEPFSGLDPINANLIKQEIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQIKQD 222
Cdd:PRK09700 159 TLMLDAKVIIMDEPTSSLTNKEVDYLFLIMNQLRKEGTAIVYISHKLAEIRRICDRYTVMKDGSSVCSGMVSDVSND 235
artP PRK11124
arginine transporter ATP-binding subunit; Provisional
 4-209 4.60e-25

arginine transporter ATP-binding subunit; Provisional


Pssm-ID: 182980 [Multi-domain]  Cd Length: 242  Bit Score: 100.86  E-value: 4.60e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFD--PQTDIHAIGYMPE 81
Cdd:PRK11124   3 IQLNGINCFYGAHQALFDITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLNIAGNHFDfsKTPSDKAIRELRR 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  82 ERG-------LYKKMKVgEQALYLAQLK--GMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPD 152
Cdd:PRK11124  83 NVGmvfqqynLWPHLTV-QQNLIEAPCRvlGLSKDQALARAEKLLERLRLKPYADRFPLHLSGGQQQRVAIARALMMEPQ 161

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 256041152 153 LLILDEPFSGLDP-INANLIKQeIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGK 209
Cdd:PRK11124 162 VLLFDEPTAALDPeITAQIVSI-IRELAETGITQVIVTHEVEVARKTASRVVYMENGH 218
MdlB COG1132
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
4-209 7.24e-25

ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];


Pssm-ID: 440747 [Multi-domain]  Cd Length: 579  Bit Score: 104.86  E-value: 7.24e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYATHKAV-DDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRP---FDPQTDIHAIGYM 79
Cdd:COG1132  340 IEFENVSFSYPGDRPVlKDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDPTSGRILIDGVDirdLTLESLRRQIGVV 419

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  80 PEERGLYKK-----MKVG---------EQALYLAQLkgmserdakdkikywfDKFeINSW---YNKKVEE----LSKGMQ 138
Cdd:COG1132  420 PQDTFLFSGtirenIRYGrpdatdeevEEAAKAAQA----------------HEF-IEALpdgYDTVVGErgvnLSGGQR 482

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 256041152 139 QKVQFISTIMHSPDLLILDEPFSGLDPINANLIKQEIFDLSKNGTTIIfSTHRMEQVEEiCDRIVLVNQGK 209
Cdd:COG1132  483 QRIAIARALLKDPPILILDEATSALDTETEALIQEALERLMKGRTTIV-IAHRLSTIRN-ADRILVLDDGR 551
metN PRK11153
DL-methionine transporter ATP-binding subunit; Provisional
 4-219 7.45e-25

DL-methionine transporter ATP-binding subunit; Provisional


Pssm-ID: 236863 [Multi-domain]  Cd Length: 343  Bit Score: 102.57  E-value: 7.45e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYATHK----AVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRpfdpqtDIhaigym 79
Cdd:PRK11153   2 IELKNISKVFPQGGrtihALNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGRVLVDGQ------DL------ 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  80 peerglykkMKVGEQALYLAQLK-GM--------SERDAKD------KIKYWfDKFEInswyNKKVEEL----------- 133
Cdd:PRK11153  70 ---------TALSEKELRKARRQiGMifqhfnllSSRTVFDnvalplELAGT-PKAEI----KARVTELlelvglsdkad 135

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 134 ------SKGMQQKVQFISTIMHSPDLLILDEPFSGLDPINAnlikQEIFDLSKN-----GTTIIFSTHRMEQVEEICDRI 202
Cdd:PRK11153 136 rypaqlSGGQKQRVAIARALASNPKVLLCDEATSALDPATT----RSILELLKDinrelGLTIVLITHEMDVVKRICDRV 211

                        250
                 ....*....|....*..
gi 256041152 203 VLVNQGKKLLDGEVKQI 219
Cdd:PRK11153 212 AVIDAGRLVEQGTVSEV 228
ABCC_Protease_Secretion cd03246
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ...
 19-209 1.34e-24

ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.


Pssm-ID: 213213 [Multi-domain]  Cd Length: 173  Bit Score: 97.67  E-value: 1.34e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  19 VDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGrpfdpqTDIHAIGympeeRGLYKKMkVGeqalYL 98
Cdd:cd03246   18 LRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRLDG------ADISQWD-----PNELGDH-VG----YL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  99 AQlkgmserDAK-------DKIkywfdkfeinswynkkveeLSKGMQQKVQFISTIMHSPDLLILDEPFSGLDPINANLI 171
Cdd:cd03246   82 PQ-------DDElfsgsiaENI-------------------LSGGQRQRLGLARALYGNPRILVLDEPNSHLDVEGERAL 135

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 256041152 172 KQEIFDLSKNGTTIIFSTHRMEQVEEiCDRIVLVNQGK 209
Cdd:cd03246  136 NQAIAALKAAGATRIVIAHRPETLAS-ADRILVLEDGR 172
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
 3-209 1.61e-24

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 103.47  E-value: 1.61e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   3 LIEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIfYPD---KGEILFNGRPFDPQ----TDIHA 75
Cdd:PRK13549   5 LLEMKNITKTFGGVKALDNVSLKVRAGEIVSLCGENGAGKSTLMKVLSGV-YPHgtyEGEIIFEGEELQASnirdTERAG 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  76 IGYMPEERGLYKKMKVGEQaLYLAQ--LKG-------MSERDAKdkikyWFDKFEINSWYNKKVEELSKGMQQKVQFIST 146
Cdd:PRK13549  84 IAIIHQELALVKELSVLEN-IFLGNeiTPGgimdydaMYLRAQK-----LLAQLKLDINPATPVGNLGLGQQQLVEIAKA 157

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 256041152 147 IMHSPDLLILDEPFSGLDPINANLIKQEIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGK 209
Cdd:PRK13549 158 LNKQARLLILDEPTASLTESETAVLLDIIRDLKAHGIACIYISHKLNEVKAISDTICVIRDGR 220
ABCC_bacteriocin_exporters cd03245
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ...
 16-214 1.67e-24

ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.


Pssm-ID: 213212 [Multi-domain]  Cd Length: 220  Bit Score: 98.82  E-value: 1.67e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  16 HKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNG---RPFDPQTDIHAIGYMPEERGLYK----- 87
Cdd:cd03245   17 IPALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLDGtdiRQLDPADLRRNIGYVPQDVTLFYgtlrd 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  88 --KMKVG----EQALYLAQLKGMSERDAKDKikywfdkfeinSWYNKKVEE----LSKGMQQKVQFISTIMHSPDLLILD 157
Cdd:cd03245   97 niTLGAPladdERILRAAELAGVTDFVNKHP-----------NGLDLQIGErgrgLSGGQRQAVALARALLNDPPILLLD 165

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 256041152 158 EPFSGLDPINANLIKQEiFDLSKNGTTIIFSTHRMeQVEEICDRIVLVNQGKKLLDG 214
Cdd:cd03245  166 EPTSAMDMNSEERLKER-LRQLLGDKTLIIITHRP-SLLDLVDRIIVMDSGRIVADG 220
PRK10851 PRK10851
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
4-209 3.79e-24

sulfate/thiosulfate ABC transporter ATP-binding protein CysA;


Pssm-ID: 182778 [Multi-domain]  Cd Length: 353  Bit Score: 100.54  E-value: 3.79e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGrpfdpqTDI---HA----I 76
Cdd:PRK10851   3 IEIANIKKSFGRTQVLNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIRFHG------TDVsrlHArdrkV 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  77 GYMPEERGLYKKMKVGEQALYLAQLKGMSERDAKDKIKY----WFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPD 152
Cdd:PRK10851  77 GFVFQHYALFRHMTVFDNIAFGLTVLPRRERPNAAAIKAkvtqLLEMVQLAHLADRYPAQLSGGQKQRVALARALAVEPQ 156

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 256041152 153 LLILDEPFSGLDPINANLIKQEIFDLSKN-GTTIIFSTHRMEQVEEICDRIVLVNQGK 209
Cdd:PRK10851 157 ILLLDEPFGALDAQVRKELRRWLRQLHEElKFTSVFVTHDQEEAMEVADRVVVMSQGN 214
PstB COG1117
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ...
 4-209 3.83e-24

ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440734 [Multi-domain]  Cd Length: 258  Bit Score: 98.57  E-value: 3.83e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGI--FYPD---KGEILFNGRP-FDPQTDIhaig 77
Cdd:COG1117   12 IEVRNLNVYYGDKQALKDINLDIPENKVTALIGPSGCGKSTLLRCLNRMndLIPGarvEGEILLDGEDiYDPDVDV---- 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  78 ymPEERglykkMKVG--------------EQALYLAQLKGMSERDAKDKIkywfdkfeinswynkkVEE----------- 132
Cdd:COG1117   88 --VELR-----RRVGmvfqkpnpfpksiyDNVAYGLRLHGIKSKSELDEI----------------VEEslrkaalwdev 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 133 ----------LSKGMQQKVQFISTIMHSPDLLILDEPFSGLDPINANLIKQEIFDLSKNgTTIIFSTHRMEQVEEICDRI 202
Cdd:COG1117  145 kdrlkksalgLSGGQQQRLCIARALAVEPEVLLMDEPTSALDPISTAKIEELILELKKD-YTIVIVTHNMQQAARVSDYT 223


                 ....*..
gi 256041152 203 VLVNQGK 209
Cdd:COG1117  224 AFFYLGE 230
ABC_choXWV_ATP TIGR03415
choline ABC transporter, ATP-binding protein; Members of this protein family are the ...
 18-219 5.22e-24

choline ABC transporter, ATP-binding protein; Members of this protein family are the ATP-binding subunit of a three-protein transporter. This family belongs, more broadly, to the family of proline and glycine-betaine transporters, but members have been identified by direct characterization and by bioinformatic means as choline transporters. Many species have several closely-related members of this family, probably with variable abilities to act additionally on related quaternary amines. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 188317 [Multi-domain]  Cd Length: 382  Bit Score: 100.62  E-value: 5.22e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   18 AVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFN--GRPFDP-QTDIHAIGYMPEER--------GLY 86
Cdd:TIGR03415  39 GVHNASLDIEEGEICVLMGLSGSGKSTLLRAVNGLNPVSRGSVLVKdgDGSVDVaNCDAATLRRLRTHRvsmvfqqfALL 118

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   87 KKMKVGEQALYLAQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEPFSGLDPI 166
Cdd:TIGR03415 119 PWRTVEENVAFGLEMQGMPKAERRKRVDEQLELVGLAQWADRKPGELSGGMQQRVGLARAFATEAPILLMDEPFSALDPL 198

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 256041152  167 NANLIKQEIFDL-SKNGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQI 219
Cdd:TIGR03415 199 IRTQLQDELLELqSKLKKTIVFVSHDLDEALKIGNRIAIMEGGRIIQHGTPEEI 252
fecE PRK11231
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
4-234 5.74e-24

Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;


Pssm-ID: 183044 [Multi-domain]  Cd Length: 255  Bit Score: 98.16  E-value: 5.74e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRP---FDPQTDIHAIGYMP 80
Cdd:PRK11231   3 LRTENLTVGYGTKRILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDKPismLSSRQLARRLALLP 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  81 EERGLYKKMKVGE-----QALYLAQLKGMSERDaKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLI 155
Cdd:PRK11231  83 QHHLTPEGITVRElvaygRSPWLSLWGRLSAED-NARVNQAMEQTRINHLADRRLTDLSGGQRQRAFLAMVLAQDTPVVL 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 156 LDEPFSGLDpIN-----ANLIKQeifdLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQIkqdFKQHLFRI 230
Cdd:PRK11231 162 LDEPTTYLD-INhqvelMRLMRE----LNTQGKTVVTVLHDLNQASRYCDHLVVLANGHVMAQGTPEEV---MTPGLLRT 233


                 ....
gi 256041152 231 GFGV 234
Cdd:PRK11231 234 VFDV 237
ABCC_cytochrome_bd cd03247
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ...
 4-214 5.78e-24

ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.


Pssm-ID: 213214 [Multi-domain]  Cd Length: 178  Bit Score: 96.23  E-value: 5.78e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHL---YKHYATHkAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPfdpqtdIHAIgymp 80
Cdd:cd03247    1 LSINNVsfsYPEQEQQ-VLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGEITLDGVP------VSDL---- 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  81 eERGLYKKMKVGEQALYLaqlkgmserdakdkikywFDkfeiNSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEPF 160
Cdd:cd03247   70 -EKALSSLISVLNQRPYL------------------FD----TTLRNNLGRRFSGGERQRLALARILLQDAPIVLLDEPT 126

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 256041152 161 SGLDPINANLIKQEIFDLSKNgTTIIFSTHRMEQVEEIcDRIVLVNQGKKLLDG 214
Cdd:cd03247  127 VGLDPITERQLLSLIFEVLKD-KTLIWITHHLTGIEHM-DKILFLENGKIIMQG 178
cbiO PRK13635
energy-coupling factor ABC transporter ATP-binding protein;
2-234 9.42e-24

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184195 [Multi-domain]  Cd Length: 279  Bit Score: 98.16  E-value: 9.42e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   2 NLIEIKHLYKHY--ATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPQT--DIHA-I 76
Cdd:PRK13635   4 EIIRVEHISFRYpdAATYALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTITVGGMVLSEETvwDVRRqV 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  77 GYM---PEERglYKKMKVGEQALYLAQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDL 153
Cdd:PRK13635  84 GMVfqnPDNQ--FVGATVQDDVAFGLENIGVPREEMVERVDQALRQVGMEDFLNREPHRLSGGQKQRVAIAGVLALQPDI 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 154 LILDEPFSGLDPINANLIKQEIFDLSKNGT-TIIFSTHRMEQVEEiCDRIVLVNQGKKLLDGEVKQIkqdFK--QHLFRI 230
Cdd:PRK13635 162 IILDEATSMLDPRGRREVLETVRQLKEQKGiTVLSITHDLDEAAQ-ADRVIVMNKGEILEEGTPEEI---FKsgHMLQEI 237


                 ....
gi 256041152 231 GFGV 234
Cdd:PRK13635 238 GLDV 241
ABCC_ATM1_transporter cd03253
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ...
 4-209 1.11e-23

ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213220 [Multi-domain]  Cd Length: 236  Bit Score: 96.92  E-value: 1.11e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYATHKAV-DDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDpQTDIH----AIGY 78
Cdd:cd03253    1 IEFENVTFAYDPGRPVlKDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSILIDGQDIR-EVTLDslrrAIGV 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  79 MPEERGL----------YKKMKVGEQALYLAQLKGMSErdakDKIKYWFDKfeinswYNKKVEE----LSKGMQQKVQFI 144
Cdd:cd03253   80 VPQDTVLfndtigynirYGRPDATDEEVIEAAKAAQIH----DKIMRFPDG------YDTIVGErglkLSGGEKQRVAIA 149

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 256041152 145 STIMHSPDLLILDEPFSGLDPINANLIKQEIFDLSKNGTTIIFsTHRMEQVEEiCDRIVLVNQGK 209
Cdd:cd03253  150 RAILKNPPILLLDEATSALDTHTEREIQAALRDVSKGRTTIVI-AHRLSTIVN-ADKIIVLKDGR 212
PRK11831 PRK11831
phospholipid ABC transporter ATP-binding protein MlaF;
1-236 1.47e-23

phospholipid ABC transporter ATP-binding protein MlaF;


Pssm-ID: 236997 [Multi-domain]  Cd Length: 269  Bit Score: 97.53  E-value: 1.47e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   1 MNLIEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGR--PFDPQTDIHA--- 75
Cdd:PRK11831   5 ANLVDMRGVSFTRGNRCIFDNISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHGEILFDGEniPAMSRSRLYTvrk 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  76 -IGYMPEERGLYKKMKVGEQALY-LAQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDL 153
Cdd:PRK11831  85 rMSMLFQSGALFTDMNVFDNVAYpLREHTQLPAPLLHSTVMMKLEAVGLRGAAKLMPSELSGGMARRAALARAIALEPDL 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 154 LILDEPFSGLDPINANLIKQEIFDLSKN-GTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQIKQD----FKQHLF 228
Cdd:PRK11831 165 IMFDEPFVGQDPITMGVLVKLISELNSAlGVTCVVVSHDVPEVLSIADHAYIVADKKIVAHGSAQALQANpdprVRQFLD 244


                 ....*...
gi 256041152 229 RIGFGVMP 236
Cdd:PRK11831 245 GIADGPVP 252
ProV COG4175
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and ...
 1-219 1.92e-23

ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443334 [Multi-domain]  Cd Length: 389  Bit Score: 99.02  E-value: 1.92e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   1 MNLIEIKHLYKHYATHK------------------------AVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPD 56
Cdd:COG4175    1 MPKIEVRNLYKIFGKRPeralklldqgkskdeilektgqtvGVNDASFDVEEGEIFVIMGLSGSGKSTLVRCLNRLIEPT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  57 KGEILFNGRpfdpqtDIHAigyMPEER----------------GLYKKMKVGEQALYLAQLKGMSERDAKDKIKYWFDKF 120
Cdd:COG4175   81 AGEVLIDGE------DITK---LSKKElrelrrkkmsmvfqhfALLPHRTVLENVAFGLEIQGVPKAERRERAREALELV 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 121 EINSWYNKKVEELSKGMQQKV--------QfistimhsPDLLILDEPFSGLDPinanLIK----QEIFDL-SKNGTTIIF 187
Cdd:COG4175  152 GLAGWEDSYPDELSGGMQQRVglaralatD--------PDILLMDEAFSALDP----LIRremqDELLELqAKLKKTIVF 219

                        250       260       270
                 ....*....|....*....|....*....|..
gi 256041152 188 STHRMEQVEEICDRIVLvnqgkkLLDGEVKQI 219
Cdd:COG4175  220 ITHDLDEALRLGDRIAI------MKDGRIVQI 245
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
 2-223 8.49e-23

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 99.32  E-value: 8.49e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152     2 NLIEIKHLYKHYA--THKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPQ-TDIH-AIG 77
Cdd:TIGR01257 1936 DILRLNELTKVYSgtSSPAVDRLCVGVRPGECFGLLGVNGAGKTTTFKMLTGDTTVTSGDATVAGKSILTNiSDVHqNMG 2015

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152    78 YMPEERGLyKKMKVGEQALYL-AQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLIL 156
Cdd:TIGR01257 2016 YCPQFDAI-DDLLTGREHLYLyARLRGVPAEEIEKVANWSIQSLGLSLYADRLAGTYSGGNKRKLSTAIALIGCPPLVLL 2094

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 256041152   157 DEPFSGLDPINANLIKQEIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQIKQDF 223
Cdd:TIGR01257 2095 DEPTTGMDPQARRMLWNTIVSIIREGRAVVLTSHSMEECEALCTRLAIMVKGAFQCLGTIQHLKSKF 2161
livF PRK11614
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
1-215 9.51e-23

high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;


Pssm-ID: 183231 [Multi-domain]  Cd Length: 237  Bit Score: 94.56  E-value: 9.51e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   1 MNLIEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPF-DPQTDI---HAI 76
Cdd:PRK11614   3 KVMLSFDKVSAHYGKIQALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVFDGKDItDWQTAKimrEAV 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  77 GYMPEERGLYKKMKVGEQalyLAQLKGMSERDA-KDKIKYWFDKFEinSWYNKKVEE---LSKGMQQKVQFISTIMHSPD 152
Cdd:PRK11614  83 AIVPEGRRVFSRMTVEEN---LAMGGFFAERDQfQERIKWVYELFP--RLHERRIQRagtMSGGEQQMLAIGRALMSQPR 157

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 256041152 153 LLILDEPFSGLDPInanlIKQEIFD----LSKNGTTIIFSTHRMEQVEEICDR--------IVLVNQGKKLLDGE 215
Cdd:PRK11614 158 LLLLDEPSLGLAPI----IIQQIFDtieqLREQGMTIFLVEQNANQALKLADRgyvlenghVVLEDTGDALLANE 228
ABCG_White cd03234
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ...
 17-214 9.70e-23

White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.


Pssm-ID: 213201 [Multi-domain]  Cd Length: 226  Bit Score: 94.26  E-value: 9.70e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  17 KAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDK---GEILFNGRPFDPQTDIHAIGYMPEERGLYKKMKVGE 93
Cdd:cd03234   21 RILNDVSLHVESGQVMAILGSSGSGKTTLLDAISGRVEGGGttsGQILFNGQPRKPDQFQKCVAYVRQDDILLPGLTVRE 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  94 QALYLAQLKGMSERDAKDKIKYWFDKFE----INSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEPFSGLDPINAN 169
Cdd:cd03234  101 TLTYTAILRLPRKSSDAIRKKRVEDVLLrdlaLTRIGGNLVKGISGGERRRVSIAVQLLWDPKVLILDEPTSGLDSFTAL 180

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 256041152 170 LIKQEIFDLSKNGTTIIFSTH--RMEqVEEICDRIVLVNQGKKLLDG 214
Cdd:cd03234  181 NLVSTLSQLARRNRIVILTIHqpRSD-LFRLFDRILLLSSGEIVYSG 226
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
 3-209 1.18e-22

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 97.83  E-value: 1.18e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   3 LIEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNgrpfdpqTDIHaIGYMPEE 82
Cdd:COG0488  315 VLELEGLSKSYGDKTLLDDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAGELEPDSGTVKLG-------ETVK-IGYFDQH 386

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  83 R-GLYKKMKVGEqalYLAQL-KGMSERDAKDKIKYW-FDKFEInswyNKKVEELSKGMQQKVQFISTIMHSPDLLILDEP 159
Cdd:COG0488  387 QeELDPDKTVLD---ELRDGaPGGTEQEVRGYLGRFlFSGDDA----FKPVGVLSGGEKARLALAKLLLSPPNVLLLDEP 459

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 256041152 160 FSGLDP--INA--NLIKQeiFDlsknGtTIIFSTHRMEQVEEICDRIVLVNQGK 209
Cdd:COG0488  460 TNHLDIetLEAleEALDD--FP----G-TVLLVSHDRYFLDRVATRILEFEDGG 506
cbiO PRK13652
cobalt transporter ATP-binding subunit; Provisional
 1-219 1.37e-22

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 172200 [Multi-domain]  Cd Length: 277  Bit Score: 94.87  E-value: 1.37e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   1 MNLIEIKHLYKHYATHK-AVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDpQTDIHAIGYM 79
Cdd:PRK13652   1 MHLIETRDLCYSYSGSKeALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSVLIRGEPIT-KENIREVRKF 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  80 -------PEERGLYKKMkvgEQALYLAQLK-GMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSP 151
Cdd:PRK13652  80 vglvfqnPDDQIFSPTV---EQDIAFGPINlGLDEETVAHRVSSALHMLGLEELRDRVPHHLSGGEKKRVAIAGVIAMEP 156

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 256041152 152 DLLILDEPFSGLDPINANLIKQEIFDLSKN-GTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQI 219
Cdd:PRK13652 157 QVLVLDEPTAGLDPQGVKELIDFLNDLPETyGMTVIFSTHQLDLVPEMADYIYVMDKGRIVAYGTVEEI 225
COG4559 COG4559
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];
3-222 1.52e-22

ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443620 [Multi-domain]  Cd Length: 258  Bit Score: 94.41  E-value: 1.52e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   3 LIEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFD-------------- 68
Cdd:COG4559    1 MLEAENLSVRLGGRTLLDDVSLTLRPGELTAIIGPNGAGKSTLLKLLTGELTPSSGEVRLNGRPLAawspwelarrravl 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  69 PQT----------DIHAIGYMPEERGLYKKMKVGEQALYLAQLKGMSERDakdkikywfdkfeinswYNkkveELSKGMQ 138
Cdd:COG4559   81 PQHsslafpftveEVVALGRAPHGSSAAQDRQIVREALALVGLAHLAGRS-----------------YQ----TLSGGEQ 139

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 139 QKVQF---ISTIMHSPD----LLILDEPFSGLDPINanliKQEIFDLSKN----GTTIIFSTHRMEQVEEICDRIVLVNQ 207
Cdd:COG4559  140 QRVQLarvLAQLWEPVDggprWLFLDEPTSALDLAH----QHAVLRLARQlarrGGGVVAVLHDLNLAAQYADRILLLHQ 215

                        250
                 ....*....|....*
gi 256041152 208 GKKLLDGEVKQIKQD 222
Cdd:COG4559  216 GRLVAQGTPEEVLTD 230
cbiO PRK13641
energy-coupling factor transporter ATPase;
17-226 2.85e-22

energy-coupling factor transporter ATPase;


Pssm-ID: 237456 [Multi-domain]  Cd Length: 287  Bit Score: 94.51  E-value: 2.85e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  17 KAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPQTDIHAIGYMPEERGLYKKM------- 89
Cdd:PRK13641  21 KGLDNISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIAGYHITPETGNKNLKKLRKKVSLVFQFpeaqlfe 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  90 -KVGEQALYLAQLKGMSERDAKDKIKYWFDKFEIN-SWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEPFSGLDPIN 167
Cdd:PRK13641 101 nTVLKDVEFGPKNFGFSEDEAKEKALKWLKKVGLSeDLISKSPFELSGGQMRRVAIAGVMAYEPEILCLDEPAAGLDPEG 180

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 256041152 168 ANLIKQEIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQIKQD---FKQH 226
Cdd:PRK13641 181 RKEMMQLFKDYQKAGHTVILVTHNMDDVAEYADDVLVLEHGKLIKHASPKEIFSDkewLKKH 242
TauB COG4525
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];
1-197 3.29e-22

ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443596 [Multi-domain]  Cd Length: 262  Bit Score: 93.77  E-value: 3.29e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   1 MNLIEIKHLYKHY----ATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPfdpqtdIHAI 76
Cdd:COG4525    1 MSMLTVRHVSVRYpgggQPQPALQDVSLTIESGEFVVALGASGCGKTTLLNLIAGFLAPSSGEITLDGVP------VTGP 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  77 GympEERG-------LYKKMKVGEQ-ALYLaQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIM 148
Cdd:COG4525   75 G---ADRGvvfqkdaLLPWLNVLDNvAFGL-RLRGVPKAERRARAEELLALVGLADFARRRIWQLSGGMRQRVGIARALA 150

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 256041152 149 HSPDLLILDEPFSGLDPINANLIKQEIFDL-SKNGTTIIFSTHrmeQVEE 197
Cdd:COG4525  151 ADPRFLLMDEPFGALDALTREQMQELLLDVwQRTGKGVFLITH---SVEE 197
PhnK COG1101
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 4-218 3.45e-22

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 440718 [Multi-domain]  Cd Length: 264  Bit Score: 93.61  E-value: 3.45e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYK--HYAT---HKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPfdpqtdihaIGY 78
Cdd:COG1101    2 LELKNLSKtfNPGTvneKRALDGLNLTIEEGDFVTVIGSNGAGKSTLLNAIAGSLPPDSGSILIDGKD---------VTK 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  79 MPEER--------------GLYKKMKVgEQALYLAQLKGMS----------ERDA-KDKIKywfdKFEIN--SWYNKKVE 131
Cdd:COG1101   73 LPEYKrakyigrvfqdpmmGTAPSMTI-EENLALAYRRGKRrglrrgltkkRRELfRELLA----TLGLGleNRLDTKVG 147

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 132 ELSKGMQQKVQFISTIMHSPDLLILDEPFSGLDPINANLIKQ---EIfdLSKNGTTIIFSTHRMEQVEEICDRIVLVNQG 208
Cdd:COG1101  148 LLSGGQRQALSLLMATLTKPKLLLLDEHTAALDPKTAALVLElteKI--VEENNLTTLMVTHNMEQALDYGNRLIMMHEG 225

                        250
                 ....*....|..
gi 256041152 209 KKLLD--GEVKQ 218
Cdd:COG1101  226 RIILDvsGEEKK 237
btuD PRK09536
corrinoid ABC transporter ATPase; Reviewed
 1-208 7.59e-22

corrinoid ABC transporter ATPase; Reviewed


Pssm-ID: 236554 [Multi-domain]  Cd Length: 402  Bit Score: 94.91  E-value: 7.59e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   1 MNLIEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDpQTDIHAIG--- 77
Cdd:PRK09536   1 MPMIDVSDLSVEFGDTTVLDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLVAGDDVE-ALSARAASrrv 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  78 -YMPEERGLYKKMKVgEQAL------YLAQLKGMSERDAKdKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHS 150
Cdd:PRK09536  80 aSVPQDTSLSFEFDV-RQVVemgrtpHRSRFDTWTETDRA-AVERAMERTGVAQFADRPVTSLSGGERQRVLLARALAQA 157

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 256041152 151 PDLLILDEPFSGLDpINANLIKQEIF-DLSKNGTTIIFSTHRMEQVEEICDRIVLVNQG 208
Cdd:PRK09536 158 TPVLLLDEPTASLD-INHQVRTLELVrRLVDDGKTAVAAIHDLDLAARYCDELVLLADG 215
PRK10982 PRK10982
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
 17-209 1.09e-21

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional


Pssm-ID: 182880 [Multi-domain]  Cd Length: 491  Bit Score: 95.18  E-value: 1.09e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  17 KAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPQTDIHA----IGYMPEERGLYKKMKVG 92
Cdd:PRK10982  12 KALDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGSILFQGKEIDFKSSKEAlengISMVHQELNLVLQRSVM 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  93 EQaLYLAQ--LKGMSERDAK--DKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEPFSGLDPINA 168
Cdd:PRK10982  92 DN-MWLGRypTKGMFVDQDKmyRDTKAIFDELDIDIDPRAKVATLSVSQMQMIEIAKAFSYNAKIVIMDEPTSSLTEKEV 170

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 256041152 169 NLIKQEIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGK 209
Cdd:PRK10982 171 NHLFTIIRKLKERGCGIVYISHKMEEIFQLCDEITILRDGQ 211
PRK10070 PRK10070
proline/glycine betaine ABC transporter ATP-binding protein ProV;
18-229 1.29e-21

proline/glycine betaine ABC transporter ATP-binding protein ProV;


Pssm-ID: 182221 [Multi-domain]  Cd Length: 400  Bit Score: 94.33  E-value: 1.29e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  18 AVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPQTDIH-------AIGYMPEERGLYKKMK 90
Cdd:PRK10070  43 GVKDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGVDIAKISDAElrevrrkKIAMVFQSFALMPHMT 122

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  91 VGEQALYLAQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEPFSGLDPINANL 170
Cdd:PRK10070 123 VLDNTAFGMELAGINAEERREKALDALRQVGLENYAHSYPDELSGGMRQRVGLARALAINPDILLMDEAFSALDPLIRTE 202

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 256041152 171 IKQEIFDL-SKNGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQI----KQDFKQHLFR 229
Cdd:PRK10070 203 MQDELVKLqAKHQRTIVFISHDLDEAMRIGDRIAIMQNGEVVQVGTPDEIlnnpANDYVRTFFR 266
PRK14239 PRK14239
phosphate transporter ATP-binding protein; Provisional
 3-219 1.35e-21

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184585 [Multi-domain]  Cd Length: 252  Bit Score: 91.76  E-value: 1.35e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   3 LIEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMIT--GIFYPD---KGEILFNGRP-FDPQTDI--- 73
Cdd:PRK14239   5 ILQVSDLSVYYNKKKALNSVSLDFYPNEITALIGPSGSGKSTLLRSINrmNDLNPEvtiTGSIVYNGHNiYSPRTDTvdl 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  74 -HAIGYMPEERGLYKkMKVGEQALYLAQLKGMSERDAKDKI--------KYWFdkfEINSWYNKKVEELSKGMQQKVQFI 144
Cdd:PRK14239  85 rKEIGMVFQQPNPFP-MSIYENVVYGLRLKGIKDKQVLDEAvekslkgaSIWD---EVKDRLHDSALGLSGGQQQRVCIA 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 256041152 145 STIMHSPDLLILDEPFSGLDPINANLIKQEIFDLsKNGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQI 219
Cdd:PRK14239 161 RVLATSPKIILLDEPTSALDPISAGKIEETLLGL-KDDYTMLLVTRSMQQASRISDRTGFFLDGDLIEYNDTKQM 234
ABC_ThiQ_thiamine_transporter cd03298
ATP-binding cassette domain of the thiamine transport system; Part of the ...
 3-214 1.42e-21

ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213265 [Multi-domain]  Cd Length: 211  Bit Score: 90.63  E-value: 1.42e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   3 LIEIKHLYKHYATHkavddISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGR--PFDPQTDiHAIGYMP 80
Cdd:cd03298    3 LDKIRFSYGEQPMH-----FDLTFAQGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLINGVdvTAAPPAD-RPVSMLF 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  81 EERGLYKKMKVgEQALYLAQLKGMSERDA-KDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEP 159
Cdd:cd03298   77 QENNLFAHLTV-EQNVGLGLSPGLKLTAEdRQAIEVALARVGLAGLEKRLPGELSGGERQRVALARVLVRDKPVLLLDEP 155

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 160 FSGLDPInanlIKQEIFDL-----SKNGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDG 214
Cdd:cd03298  156 FAALDPA----LRAEMLDLvldlhAETKMTVLMVTHQPEDAKRLAQRVVFLDNGRIAAQG 211
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
 3-209 1.97e-21

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 94.51  E-value: 1.97e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152    3 LIEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIfYPD---KGEILFNGRPFDPQ----TDIHA 75
Cdd:TIGR02633   1 LLEMKGIVKTFGGVKALDGIDLEVRPGECVGLCGENGAGKSTLMKILSGV-YPHgtwDGEIYWSGSPLKASnirdTERAG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   76 IGYMPEERGLYKKMKVGEQaLYLAQ---LKG--MSERDAKDKIKYWFDKFEINSWYN-KKVEELSKGMQQKVQFISTIMH 149
Cdd:TIGR02633  80 IVIIHQELTLVPELSVAEN-IFLGNeitLPGgrMAYNAMYLRAKNLLRELQLDADNVtRPVGDYGGGQQQLVEIAKALNK 158

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  150 SPDLLILDEPFSGLDPINANLIKQEIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGK 209
Cdd:TIGR02633 159 QARLLILDEPSSSLTEKETEILLDIIRDLKAHGVACVYISHKLNEVKAVCDTICVIRDGQ 218
CydD TIGR02857
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ...
 17-205 2.29e-21

thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD


Pssm-ID: 274323 [Multi-domain]  Cd Length: 529  Bit Score: 94.28  E-value: 2.29e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   17 KAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRP---FDPQTDIHAIGYMPEERGLYKKMKVGE 93
Cdd:TIGR02857 336 PALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEGSIAVNGVPladADADSWRDQIAWVPQHPFLFAGTIAEN 415

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   94 QALYL-----AQLKGMSER-DAKDKIKywfdkfEINSWYNKKVEE----LSKGMQQKVQFISTIMHSPDLLILDEPFSGL 163
Cdd:TIGR02857 416 IRLARpdasdAEIREALERaGLDEFVA------ALPQGLDTPIGEggagLSGGQAQRLALARAFLRDAPLLLLDEPTAHL 489

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 256041152  164 DPINANLIKQEIFDLSKNGTTIIfSTHRMEQVEEiCDRIVLV 205
Cdd:TIGR02857 490 DAETEAEVLEALRALAQGRTVLL-VTHRLALAAL-ADRIVVL 529
ModC COG4148
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ...
 21-209 2.47e-21

ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis


Pssm-ID: 443319 [Multi-domain]  Cd Length: 358  Bit Score: 92.86  E-value: 2.47e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  21 DISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRP-FDPQTDIH------AIGYMPEERGLYKKMKVGE 93
Cdd:COG4148   17 DVDFTLPGRGVTALFGPSGSGKTTLLRAIAGLERPDSGRIRLGGEVlQDSARGIFlpphrrRIGYVFQEARLFPHLSVRG 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  94 QALYlaqlkGMS-ERDAKDKIKywFDK----FEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEPFSGLDpiNA 168
Cdd:COG4148   97 NLLY-----GRKrAPRAERRIS--FDEvvelLGIGHLLDRRPATLSGGERQRVAIGRALLSSPRLLLMDEPLAALD--LA 167

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 256041152 169 NliKQEI----------FDLSkngttIIFSTHRMEQVEEICDRIVLVNQGK 209
Cdd:COG4148  168 R--KAEIlpylerlrdeLDIP-----ILYVSHSLDEVARLADHVVLLEQGR 211
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
 5-209 4.24e-21

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 93.46  E-value: 4.24e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   5 EIKHL--YKHYATH-KAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIfYPDK--GEILFNGRPFD---PQTDI-HA 75
Cdd:PRK13549 261 EVRNLtaWDPVNPHiKRVDDVSFSLRRGEILGIAGLVGAGRTELVQCLFGA-YPGRweGEIFIDGKPVKirnPQQAIaQG 339

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  76 IGYMPEER---GLYKKMKVGEQALY--LAQLKGMSERDAKDKIKYwfdkfeINSWYNK----------KVEELSKGMQQK 140
Cdd:PRK13549 340 IAMVPEDRkrdGIVPVMGVGKNITLaaLDRFTGGSRIDDAAELKT------ILESIQRlkvktaspelAIARLSGGNQQK 413

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 256041152 141 VQFISTIMHSPDLLILDEPFSGLDpINAnliKQEI----FDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGK 209
Cdd:PRK13549 414 AVLAKCLLLNPKILILDEPTRGID-VGA---KYEIykliNQLVQQGVAIIVISSELPEVLGLSDRVLVMHEGK 482
cbiO PRK13631
cobalt transporter ATP-binding subunit; Provisional
 17-241 4.46e-21

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237451 [Multi-domain]  Cd Length: 320  Bit Score: 91.45  E-value: 4.46e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  17 KAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEI----LFNGRPFDPQTDIhaIGYMPEERGLYKKMK-- 90
Cdd:PRK13631  40 VALNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLIKSKYGTIqvgdIYIGDKKNNHELI--TNPYSKKIKNFKELRrr 117

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  91 ------VGEQALYLAQLK----------GMSERDAKDKIKYWFDKFEINSWY-NKKVEELSKGMQQKVQFISTIMHSPDL 153
Cdd:PRK13631 118 vsmvfqFPEYQLFKDTIEkdimfgpvalGVKKSEAKKLAKFYLNKMGLDDSYlERSPFGLSGGQKRRVAIAGILAIQPEI 197

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 154 LILDEPFSGLDPINANLIKQEIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQIKQDfkQHLFRIGFG 233
Cdd:PRK13631 198 LIFDEPTAGLDPKGEHEMMQLILDAKANNKTVFVITHTMEHVLEVADEVIVMDKGKILKTGTPYEIFTD--QHIINSTSI 275


                 ....*...
gi 256041152 234 VMPNFAQV 241
Cdd:PRK13631 276 QVPRVIQV 283
ABCF_EF-3 cd03221
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ...
 4-209 6.33e-21

ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.


Pssm-ID: 213188 [Multi-domain]  Cd Length: 144  Bit Score: 87.12  E-value: 6.33e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEIlfngrpfdpqtdihaigympeer 83
Cdd:cd03221    1 IELENLSKTYGGKLLLKDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEGIV----------------------- 57

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  84 glykkmkvgeqalylaqlkgmsERDAKDKIKYwfdkfeinswynkkVEELSKGMQQKVQFISTIMHSPDLLILDEPFSGL 163
Cdd:cd03221   58 ----------------------TWGSTVKIGY--------------FEQLSGGEKMRLALAKLLLENPNLLLLDEPTNHL 101

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 256041152 164 DPINANLIKQEIfdLSKNGtTIIFSTHRMEQVEEICDRIVLVNQGK 209
Cdd:cd03221  102 DLESIEALEEAL--KEYPG-TVILVSHDRYFLDQVATKIIELEDGK 144
PRK10619 PRK10619
histidine ABC transporter ATP-binding protein HisP;
2-209 6.45e-21

histidine ABC transporter ATP-binding protein HisP;


Pssm-ID: 182592 [Multi-domain]  Cd Length: 257  Bit Score: 90.03  E-value: 6.45e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   2 NLIEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNG------RPFDPQTDIHA 75
Cdd:PRK10619   4 NKLNVIDLHKRYGEHEVLKGVSLQANAGDVISIIGSSGSGKSTFLRCINFLEKPSEGSIVVNGqtinlvRDKDGQLKVAD 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  76 IGYMPEER----------GLYKKMKVGEQALYL-AQLKGMSERDAKDKIKYWFDKFEINSWYNKKVE-ELSKGMQQKVQF 143
Cdd:PRK10619  84 KNQLRLLRtrltmvfqhfNLWSHMTVLENVMEApIQVLGLSKQEARERAVKYLAKVGIDERAQGKYPvHLSGGQQQRVSI 163

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 256041152 144 ISTIMHSPDLLILDEPFSGLDPINANLIKQEIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGK 209
Cdd:PRK10619 164 ARALAMEPEVLLFDEPTSALDPELVGEVLRIMQQLAEEGKTMVVVTHEMGFARHVSSHVIFLHQGK 229
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
 19-215 6.74e-21

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 92.76  E-value: 6.74e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  19 VDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFD---PQTDI-HAIGYMPEER---GLYKKMKV 91
Cdd:PRK10762 268 VNDVSFTLRKGEILGVSGLMGAGRTELMKVLYGALPRTSGYVTLDGHEVVtrsPQDGLaNGIVYISEDRkrdGLVLGMSV 347

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  92 GEQ----AL-YLA----QLKGMSERDAKDKikyWFDKFEINS-WYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEPFS 161
Cdd:PRK10762 348 KENmsltALrYFSraggSLKHADEQQAVSD---FIRLFNIKTpSMEQAIGLLSGGNQQKVAIARGLMTRPKVLILDEPTR 424

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 256041152 162 GLDpINAnliKQEIFDL----SKNGTTIIFSTHRMEQVEEICDRIVLVNQGKklLDGE 215
Cdd:PRK10762 425 GVD-VGA---KKEIYQLinqfKAEGLSIILVSSEMPEVLGMSDRILVMHEGR--ISGE 476
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
 3-209 9.70e-21

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 92.20  E-value: 9.70e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152    3 LIEIKHLYKHYATH---KAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIfYPDK--GEILFNGRPFD---PQTDI- 73
Cdd:TIGR02633 257 ILEARNLTCWDVINphrKRVDDVSFSLRRGEILGVAGLVGAGRTELVQALFGA-YPGKfeGNVFINGKPVDirnPAQAIr 335

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   74 HAIGYMPEER---GLYKKMKVGeQALYLAQLKGMSER----DAK--DKIKYWFDKFEINSWY-NKKVEELSKGMQQKVQF 143
Cdd:TIGR02633 336 AGIAMVPEDRkrhGIVPILGVG-KNITLSVLKSFCFKmridAAAelQIIGSAIQRLKVKTASpFLPIGRLSGGNQQKAVL 414

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 256041152  144 ISTIMHSPDLLILDEPFSGLDPINANLIKQEIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGK 209
Cdd:TIGR02633 415 AKMLLTNPRVLILDEPTRGVDVGAKYEIYKLINQLAQEGVAIIVVSSELAEVLGLSDRVLVIGEGK 480
nikE PRK10419
nickel ABC transporter ATP-binding protein NikE;
1-209 1.10e-20

nickel ABC transporter ATP-binding protein NikE;


Pssm-ID: 236689 [Multi-domain]  Cd Length: 268  Bit Score: 89.75  E-value: 1.10e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   1 MNLIEIKHLYKHYAT--------HKAV-DDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRP----- 66
Cdd:PRK10419   1 MTLLNVSGLSHHYAHgglsgkhqHQTVlNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVSWRGEPlakln 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  67 ---------------------FDPQTDIHAIgympeerglykkmkVGEQalyLAQLKGMSERDAKDKIKYWFDKFEIN-S 124
Cdd:PRK10419  81 raqrkafrrdiqmvfqdsisaVNPRKTVREI--------------IREP---LRHLLSLDKAERLARASEMLRAVDLDdS 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 125 WYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEPFSGLDpinanLIKQ-EIFDLSKN-----GTTIIFSTHRMEQVEEI 198
Cdd:PRK10419 144 VLDKRPPQLSGGQLQRVCLARALAVEPKLLILDEAVSNLD-----LVLQaGVIRLLKKlqqqfGTACLFITHDLRLVERF 218

                        250
                 ....*....|.
gi 256041152 199 CDRIVLVNQGK 209
Cdd:PRK10419 219 CQRVMVMDNGQ 229
ABC_CcmA_heme_exporter cd03231
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ...
 22-201 1.18e-20

Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.


Pssm-ID: 213198 [Multi-domain]  Cd Length: 201  Bit Score: 87.93  E-value: 1.18e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  22 ISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPQTDIHA--IGYMPEERGLYKKMKVGEQALYLA 99
Cdd:cd03231   19 LSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVLLNGGPLDFQRDSIArgLLYLGHAPGIKTTLSVLENLRFWH 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 100 QLKGmserdaKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEPFSGLDPINANLIKQEIFDLS 179
Cdd:cd03231   99 ADHS------DEQVEEALARVGLNGFEDRPVAQLSAGQQRRVALARLLLSGRPLWILDEPTTALDKAGVARFAEAMAGHC 172

                        170       180
                 ....*....|....*....|..
gi 256041152 180 KNGTTIIFSTHRMEQVEEICDR 201
Cdd:cd03231  173 ARGGMVVLTTHQDLGLSEAGAR 194
ABCC_Glucan_exporter_like cd03254
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ...
 4-214 1.45e-20

ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213221 [Multi-domain]  Cd Length: 229  Bit Score: 88.44  E-value: 1.45e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYA-THKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDpQTDIHA----IGY 78
Cdd:cd03254    3 IEFENVNFSYDeKKPVLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQILIDGIDIR-DISRKSlrsmIGV 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  79 MPEERGLYK--------------KMKVGEQALYLAQLKGMSERDAKDkikywfdkfeinswYNKKVEE----LSKGMQQK 140
Cdd:cd03254   82 VLQDTFLFSgtimenirlgrpnaTDEEVIEAAKEAGAHDFIMKLPNG--------------YDTVLGEnggnLSQGERQL 147

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 256041152 141 VQFISTIMHSPDLLILDEPFSGLDPINANLIKQEIFDLSKNGTTIIFStHRMEQVEEiCDRIVLVNQGKKLLDG 214
Cdd:cd03254  148 LAIARAMLRDPKILILDEATSNIDTETEKLIQEALEKLMKGRTSIIIA-HRLSTIKN-ADKILVLDDGKIIEEG 219
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
 4-164 3.52e-20

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 90.76  E-value: 3.52e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152    4 IEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNgrpfdpqtDIHAIGYMPEER 83
Cdd:TIGR03719 323 IEAENLTKAFGDKLLIDDLSFKLPPGGIVGVIGPNGAGKSTLFRMITGQEQPDSGTIEIG--------ETVKLAYVDQSR 394

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   84 -GLYKKMKVGEQAlylaqlkgmseRDAKDKIKywFDKFEINS-----WYN-------KKVEELSKGMQQKVQFISTIMHS 150
Cdd:TIGR03719 395 dALDPNKTVWEEI-----------SGGLDIIK--LGKREIPSrayvgRFNfkgsdqqKKVGQLSGGERNRVHLAKTLKSG 461

                         170
                  ....*....|....
gi 256041152  151 PDLLILDEPFSGLD 164
Cdd:TIGR03719 462 GNVLLLDEPTNDLD 475
cbiO PRK13632
cobalt transporter ATP-binding subunit; Provisional
 4-219 5.70e-20

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237452 [Multi-domain]  Cd Length: 271  Bit Score: 87.74  E-value: 5.70e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYATHK--AVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPQT---------- 71
Cdd:PRK13632   8 IKVENVSFSYPNSEnnALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIKIDGITISKENlkeirkkigi 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  72 -----DIHAIGYMPEER---GLYKKMkvgeqalylaqlkgMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQF 143
Cdd:PRK13632  88 ifqnpDNQFIGATVEDDiafGLENKK--------------VPPKKMKDIIDDLAKKVGMEDYLDKEPQNLSGGQKQRVAI 153

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 256041152 144 ISTIMHSPDLLILDEPFSGLDPINANLIKQEIFDLSKNGT-TIIFSTHRMEQVeEICDRIVLVNQGKKLLDGEVKQI 219
Cdd:PRK13632 154 ASVLALNPEIIIFDESTSMLDPKGKREIKKIMVDLRKTRKkTLISITHDMDEA-ILADKVIVFSEGKLIAQGKPKEI 229
COG4674 COG4674
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 17-222 7.50e-20

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443710 [Multi-domain]  Cd Length: 250  Bit Score: 86.71  E-value: 7.50e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  17 KAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGrpfdpqTDIHaigYMPEER------------- 83
Cdd:COG4674   24 KALNDLSLYVDPGELRVIIGPNGAGKTTLMDVITGKTRPDSGSVLFGG------TDLT---GLDEHEiarlgigrkfqkp 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  84 GLYKKMKVgEQALYLAQ---------LKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLL 154
Cdd:COG4674   95 TVFEELTV-FENLELALkgdrgvfasLFARLTAEERDRIEEVLETIGLTDKADRLAGLLSHGQKQWLEIGMLLAQDPKLL 173

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 256041152 155 ILDEPFSGLDP----INANLIKQeifdLSKNgTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQIKQD 222
Cdd:COG4674  174 LLDEPVAGMTDaeteRTAELLKS----LAGK-HSVVVVEHDMEFVRQIARKVTVLHQGSVLAEGSLDEVQAD 240
PRK15056 PRK15056
manganese/iron ABC transporter ATP-binding protein;
16-205 7.80e-20

manganese/iron ABC transporter ATP-binding protein;


Pssm-ID: 185016 [Multi-domain]  Cd Length: 272  Bit Score: 87.25  E-value: 7.80e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  16 HKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPQTDIHAIGYMPEERG-------LYKK 88
Cdd:PRK15056  20 HTALRDASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLASGKISILGQPTRQALQKNLVAYVPQSEEvdwsfpvLVED 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  89 MKVGEQALYLAQLKGMSERDaKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEPFSGLDPINA 168
Cdd:PRK15056 100 VVMMGRYGHMGWLRRAKKRD-RQIVTAALARVDMVEFRHRQIGELSGGQKKRVFLARAIAQQGQVILLDEPFTGVDVKTE 178

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 256041152 169 NLIKQEIFDLSKNGTTIIFSTHRMEQVEEICDRIVLV 205
Cdd:PRK15056 179 ARIISLLRELRDEGKTMLVSTHNLGSVTEFCDYTVMV 215
CeuD COG4604
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ...
 4-219 8.61e-20

ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443654 [Multi-domain]  Cd Length: 252  Bit Score: 86.68  E-value: 8.61e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRpfdpqtDIHAIgympEER 83
Cdd:COG4604    2 IEIKNVSKRYGGKVVLDDVSLTIPKGGITALIGPNGAGKSTLLSMISRLLPPDSGEVLVDGL------DVATT----PSR 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  84 GLYKKMKVGEQALYLA------QL---------KG-MSERDaKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVqFIS-T 146
Cdd:COG4604   72 ELAKRLAILRQENHINsrltvrELvafgrfpysKGrLTAED-REIIDEAIAYLDLEDLADRYLDELSGGQRQRA-FIAmV 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 147 IMHSPDLLILDEPFSGLDPINANLIKQEIFDLSKN-GTTIIFSTHrmeqveEI------CDRIVLVNQGKKLLDGEVKQI 219
Cdd:COG4604  150 LAQDTDYVLLDEPLNNLDMKHSVQMMKLLRRLADElGKTVVIVLH------DInfascyADHIVAMKDGRVVAQGTPEEI 223
PRK14247 PRK14247
phosphate ABC transporter ATP-binding protein; Provisional
 1-227 8.89e-20

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172735 [Multi-domain]  Cd Length: 250  Bit Score: 86.89  E-value: 8.89e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   1 MNLIEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGI--FYPD---KGEILFNGRPF------DP 69
Cdd:PRK14247   1 MNKIEIRDLKVSFGQVEVLDGVNLEIPDNTITALMGPSGSGKSTLLRVFNRLieLYPEarvSGEVYLDGQDIfkmdviEL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  70 QTDIHAIGYMPE---ERGLYKKMKVGEQALYLAQLKGMSE---RDAKDKIKYWFdkfEINSWYNKKVEELSKGMQQKVQF 143
Cdd:PRK14247  81 RRRVQMVFQIPNpipNLSIFENVALGLKLNRLVKSKKELQervRWALEKAQLWD---EVKDRLDAPAGKLSGGQQQRLCI 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 144 ISTIMHSPDLLILDEPFSGLDPINANLIKQEIFDLSKNgTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQIKQDF 223
Cdd:PRK14247 158 ARALAFQPEVLLADEPTANLDPENTAKIESLFLELKKD-MTIVLVTHFPQQAARISDYVAFLYKGQIVEWGPTREVFTNP 236


                 ....
gi 256041152 224 KQHL 227
Cdd:PRK14247 237 RHEL 240
ABCC_Hemolysin cd03252
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ...
 4-214 1.44e-19

ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.


Pssm-ID: 213219 [Multi-domain]  Cd Length: 237  Bit Score: 86.00  E-value: 1.44e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYATHKAV--DDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPF---DPQTDIHAIGY 78
Cdd:cd03252    1 ITFEHVRFRYKPDGPVilDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLVDGHDLalaDPAWLRRQVGV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  79 MPEERGLYKK------------MKVgEQALYLAQLKGmserdAKDKIKywfdkfEINSWYNKKVEE----LSKGMQQKVQ 142
Cdd:cd03252   81 VLQENVLFNRsirdnialadpgMSM-ERVIEAAKLAG-----AHDFIS------ELPEGYDTIVGEqgagLSGGQRQRIA 148

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 256041152 143 FISTIMHSPDLLILDEPFSGLDPINANLIKQEIFDLSKNGTTIIFStHRMEQVEEiCDRIVLVNQGKKLLDG 214
Cdd:cd03252  149 IARALIHNPRILIFDEATSALDYESEHAIMRNMHDICAGRTVIIIA-HRLSTVKN-ADRIIVMEKGRIVEQG 218
cbiO PRK13644
energy-coupling factor transporter ATPase;
18-222 1.51e-19

energy-coupling factor transporter ATPase;


Pssm-ID: 106587 [Multi-domain]  Cd Length: 274  Bit Score: 86.58  E-value: 1.51e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  18 AVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPQTDIHAIGYM-------PEE----RGLY 86
Cdd:PRK13644  17 ALENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLVSGIDTGDFSKLQGIRKLvgivfqnPETqfvgRTVE 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  87 KKMKVGEQALYLAQLkgmserDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEPFSGLDPI 166
Cdd:PRK13644  97 EDLAFGPENLCLPPI------EIRKRVDRALAEIGLEKYRHRSPKTLSGGQGQCVALAGILTMEPECLIFDEVTSMLDPD 170

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 256041152 167 NANLIKQEIFDLSKNGTTIIFSTHRMEQVeEICDRIVLVNQGKKLLDGEVKQIKQD 222
Cdd:PRK13644 171 SGIAVLERIKKLHEKGKTIVYITHNLEEL-HDADRIIVMDRGKIVLEGEPENVLSD 225
type_I_sec_PrtD TIGR01842
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in ...
 16-223 1.55e-19

type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 200134 [Multi-domain]  Cd Length: 544  Bit Score: 88.94  E-value: 1.55e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   16 HKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNG---RPFDPQTDIHAIGYMPEERGLYKKM--- 89
Cdd:TIGR01842 331 KPTLRGISFSLQAGEALAIIGPSGSGKSTLARLIVGIWPPTSGSVRLDGadlKQWDRETFGKHIGYLPQDVELFPGTvae 410

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   90 ---KVGEQA-----LYLAQLKGMSERDAKDKIKYwfdkfeiNSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEPFS 161
Cdd:TIGR01842 411 niaRFGENAdpekiIEAAKLAGVHELILRLPDGY-------DTVIGPGGATLSGGQRQRIALARALYGDPKLVVLDEPNS 483

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 256041152  162 GLDPINANLIKQEIFDLSKNGTTIIFSTHRMEQVEEIcDRIVLVNQGKKLLDGEVKQIKQDF 223
Cdd:TIGR01842 484 NLDEEGEQALANAIKALKARGITVVVITHRPSLLGCV-DKILVLQDGRIARFGERDEVLAKL 544
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
 6-209 1.86e-19

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 88.58  E-value: 1.86e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   6 IKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGrpfdpqtDIHaIGYMPEERGL 85
Cdd:COG0488    1 LENLSKSFGGRPLLDDVSLSINPGDRIGLVGRNGAGKSTLLKILAGELEPDSGEVSIPK-------GLR-IGYLPQEPPL 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  86 YKKMKVGEQAL------------YLAQLKGMSERDAK-DKIKYWFDKFE-INSW-------------------YNKKVEE 132
Cdd:COG0488   73 DDDLTVLDTVLdgdaelraleaeLEELEAKLAEPDEDlERLAELQEEFEaLGGWeaearaeeilsglgfpeedLDRPVSE 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 133 LSKGMQQKVQFISTIMHSPDLLILDEPFSGLDpINA-----NLIKQEifdlskNGtTIIFSTH-R--MEQVeeiCDRIVL 204
Cdd:COG0488  153 LSGGWRRRVALARALLSEPDLLLLDEPTNHLD-LESiewleEFLKNY------PG-TVLVVSHdRyfLDRV---ATRILE 221


                 ....*
gi 256041152 205 VNQGK 209
Cdd:COG0488  222 LDRGK 226
tauB PRK11248
taurine ABC transporter ATP-binding subunit;
3-164 4.57e-19

taurine ABC transporter ATP-binding subunit;


Pssm-ID: 183056 [Multi-domain]  Cd Length: 255  Bit Score: 84.75  E-value: 4.57e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   3 LIEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFD-PQTDihaIGYMPE 81
Cdd:PRK11248   1 MLQISHLYADYGGKPALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSITLDGKPVEgPGAE---RGVVFQ 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  82 ERGLYKKMKVGEQALYLAQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEPFS 161
Cdd:PRK11248  78 NEGLLPWRNVQDNVAFGLQLAGVEKMQRLEIAHQMLKKVGLEGAEKRYIWQLSGGQRQRVGIARALAANPQLLLLDEPFG 157


                 ...
gi 256041152 162 GLD 164
Cdd:PRK11248 158 ALD 160
tagH PRK13545
teichoic acids export protein ATP-binding subunit; Provisional
 16-227 5.20e-19

teichoic acids export protein ATP-binding subunit; Provisional


Pssm-ID: 184130 [Multi-domain]  Cd Length: 549  Bit Score: 87.25  E-value: 5.20e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  16 HKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGrpfdpQTDIHAIGympeeRGLYKKMKVGEQA 95
Cdd:PRK13545  37 HYALNNISFEVPEGEIVGIIGLNGSGKSTLSNLIAGVTMPNKGTVDIKG-----SAALIAIS-----SGLNGQLTGIENI 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  96 LYLAQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEPFSGLDPINANLIKQEI 175
Cdd:PRK13545 107 ELKGLMMGLTKEKIKEIIPEIIEFADIGKFIYQPVKTYSSGMKSRLGFAISVHINPDILVIDEALSVGDQTFTKKCLDKM 186

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 256041152 176 FDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQIKQDFKQHL 227
Cdd:PRK13545 187 NEFKEQGKTIFFISHSLSQVKSFCTKALWLHYGQVKEYGDIKEVVDHYDEFL 238
PRK11264 PRK11264
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
 1-225 6.75e-19

putative amino-acid ABC transporter ATP-binding protein YecC; Provisional


Pssm-ID: 183063 [Multi-domain]  Cd Length: 250  Bit Score: 84.42  E-value: 6.75e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   1 MNLIEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEI------LFNGRPFDPQTDI- 73
Cdd:PRK11264   1 MSAIEVKNLVKKFHGQTVLHGIDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGTIrvgditIDTARSLSQQKGLi 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  74 ----HAIGYMPEERGLYKKMKVGEQALY-LAQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIM 148
Cdd:PRK11264  81 rqlrQHVGFVFQNFNLFPHRTVLENIIEgPVIVKGEPKEEATARARELLAKVGLAGKETSYPRRLSGGQQQRVAIARALA 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 256041152 149 HSPDLLILDEPFSGLDPINANLIKQEIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQIKQDFKQ 225
Cdd:PRK11264 161 MRPEVILFDEPTSALDPELVGEVLNTIRQLAQEKRTMVIVTHEMSFARDVADRAIFMDQGRIVEQGPAKALFADPQQ 237
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
4-221 9.86e-19

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 86.72  E-value: 9.86e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEI-LFNGrpfdpqtDI--------- 73
Cdd:NF033858   2 ARLEGVSHRYGKTVALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRVeVLGG-------DMadarhrrav 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  74 -HAIGYMPEERG--LYKKMKVGEQALYLAQLKGMS--ERDAKdkikywfdkfeinswynkkVEEL--------------- 133
Cdd:NF033858  75 cPRIAYMPQGLGknLYPTLSVFENLDFFGRLFGQDaaERRRR-------------------IDELlratglapfadrpag 135

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 134 --SKGMQQKVQFISTIMHSPDLLILDEPFSGLDPinanLIKQEIFDL------SKNGTTIIFSTHRMEQVEEiCDRIVLV 205
Cdd:NF033858 136 klSGGMKQKLGLCCALIHDPDLLILDEPTTGVDP----LSRRQFWELidriraERPGMSVLVATAYMEEAER-FDWLVAM 210

                        250
                 ....*....|....*.
gi 256041152 206 NQGKKLLDGEVKQIKQ 221
Cdd:NF033858 211 DAGRVLATGTPAELLA 226
ccmA TIGR01189
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ...
 22-190 1.01e-18

heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]


Pssm-ID: 273491 [Multi-domain]  Cd Length: 198  Bit Score: 82.41  E-value: 1.01e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   22 ISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPQTD-----IHAIGYMPeerGLYKKMKVGEQAL 96
Cdd:TIGR01189  19 LSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRPDSGEVRWNGTPLAEQRDephenILYLGHLP---GLKPELSALENLH 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   97 YLAQLKGMSERDAKDKIkywfDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEPFSGLDPINANLIKQEIF 176
Cdd:TIGR01189  96 FWAAIHGGAQRTIEDAL----AAVGLTGFEDLPAAQLSAGQQRRLALARLWLSRRPLWILDEPTTALDKAGVALLAGLLR 171

                         170
                  ....*....|....
gi 256041152  177 DLSKNGTTIIFSTH 190
Cdd:TIGR01189 172 AHLARGGIVLLTTH 185
PRK13546 PRK13546
teichoic acids export ABC transporter ATP-binding subunit TagH;
15-227 1.50e-18

teichoic acids export ABC transporter ATP-binding subunit TagH;


Pssm-ID: 184131 [Multi-domain]  Cd Length: 264  Bit Score: 83.71  E-value: 1.50e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  15 THKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGrpfdpQTDIHAIgympeERGLYKKMKVGEQ 94
Cdd:PRK13546  36 TFFALDDISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTVGKVDRNG-----EVSVIAI-----SAGLSGQLTGIEN 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  95 ALYLAQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEPFSGLDPINANLIKQE 174
Cdd:PRK13546 106 IEFKMLCMGFKRKEIKAMTPKIIEFSELGEFIYQPVKKYSSGMRAKLGFSINITVNPDILVIDEALSVGDQTFAQKCLDK 185

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 256041152 175 IFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQIKQDFKQHL 227
Cdd:PRK13546 186 IYEFKEQNKTIFFVSHNLGQVRQFCTKIAWIEGGKLKDYGELDDVLPKYEAFL 238
bacteriocin_ABC TIGR01193
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The ...
 4-219 1.65e-18

ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The amino terminal domain (pfam03412) processes the N-terminal leader peptide from the bacteriocin while C-terminal domains resemble ABC transporter membrane protein and ATP-binding cassette domain. In general, bacteriocins are agents which are responsible for killing or inhibiting the closely related species or even different strains of the same species. Bacteriocins are usually encoded by bacterial plasmids. Bacteriocins are named after the species and hence in literature one encounters various names e.g., leucocin from Leuconostic geldium; pedicocin from Pedicoccus acidilactici; sakacin from Lactobacillus sake etc. [Protein fate, Protein and peptide secretion and trafficking, Protein fate, Protein modification and repair, Transport and binding proteins, Other]


Pssm-ID: 130261 [Multi-domain]  Cd Length: 708  Bit Score: 85.95  E-value: 1.65e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152    4 IEIKHL-YKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDpQTDIHA----IGY 78
Cdd:TIGR01193 474 IVINDVsYSYGYGSNILSDISLTIKMNSKTTIVGMSGSGKSTLAKLLVGFFQARSGEILLNGFSLK-DIDRHTlrqfINY 552

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   79 MPEERGLYKKMKVgeQALYLAQLKGMSERDAKDKIKYWFDKFEINSW---YNKKVEE----LSKGMQQKVQFISTIMHSP 151
Cdd:TIGR01193 553 LPQEPYIFSGSIL--ENLLLGAKENVSQDEIWAACEIAEIKDDIENMplgYQTELSEegssISGGQKQRIALARALLTDS 630

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 256041152  152 DLLILDEPFSGLDPINANLIKQEIFDLskNGTTIIFSTHRMEqVEEICDRIVLVNQGKKLLDGEVKQI 219
Cdd:TIGR01193 631 KVLILDESTSNLDTITEKKIVNNLLNL--QDKTIIFVAHRLS-VAKQSDKIIVLDHGKIIEQGSHDEL 695
PRK13651 PRK13651
cobalt transporter ATP-binding subunit; Provisional
 5-224 2.55e-18

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184210 [Multi-domain]  Cd Length: 305  Bit Score: 83.60  E-value: 2.55e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   5 EIKHLY-KHYATH-KAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPQTDIHAIGYMPEE 82
Cdd:PRK13651   7 NIVKIFnKKLPTElKALDNVSVEINQGEFIAIIGQTGSGKTTFIEHLNALLLPDTGTIEWIFKDEKNKKKTKEKEKVLEK 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  83 ----RGLYKKMK--------VG------EQALYLAQLK----------GMSERDAKDKIKYWFDKFEINSWYNKKVE-EL 133
Cdd:PRK13651  87 lviqKTRFKKIKkikeirrrVGvvfqfaEYQLFEQTIEkdiifgpvsmGVSKEEAKKRAAKYIELVGLDESYLQRSPfEL 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 134 SKGMQQKVQFISTIMHSPDLLILDEPFSGLDPINANLIkQEIFD-LSKNGTTIIFSTHRMEQVEEICDRIVLVNQGKKLL 212
Cdd:PRK13651 167 SGGQKRRVALAGILAMEPDFLVFDEPTAGLDPQGVKEI-LEIFDnLNKQGKTIILVTHDLDNVLEWTKRTIFFKDGKIIK 245

                        250
                 ....*....|..
gi 256041152 213 DGEVKQIKQDFK 224
Cdd:PRK13651 246 DGDTYDILSDNK 257
BtuD COG4138
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ...
 22-232 2.68e-18

ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];


Pssm-ID: 443313 [Multi-domain]  Cd Length: 248  Bit Score: 82.58  E-value: 2.68e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  22 ISFAIPKGSIFGLLGPNGAGKTTLLRMITGIfYPDKGEILFNGRPFDpQTDIHAI----GYMPEERGLYKKMKVGeQALY 97
Cdd:COG4138   15 ISAQVNAGELIHLIGPNGAGKSTLLARMAGL-LPGQGEILLNGRPLS-DWSAAELarhrAYLSQQQSPPFAMPVF-QYLA 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  98 LAQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMH-----SPD--LLILDEPFSGLDpinanl 170
Cdd:COG4138   92 LHQPAGASSEAVEQLLAQLAEALGLEDKLSRPLTQLSGGEWQRVRLAAVLLQvwptiNPEgqLLLLDEPMNSLD------ 165

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 256041152 171 IKQEI-FD-----LSKNGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQIKQDFK-QHLFRIGF 232
Cdd:COG4138  166 VAQQAaLDrllreLCQQGITVVMSSHDLNHTLRHADRVWLLKQGKLVASGETAEVMTPENlSEVFGVKF 234
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
 4-164 2.74e-18

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 85.17  E-value: 2.74e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEIlfngrpfdpqtdihaigympeer 83
Cdd:PRK11819 325 IEAENLSKSFGDRLLIDDLSFSLPPGGIVGIIGPNGAGKSTLFKMITGQEQPDSGTI----------------------- 381

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  84 glykkmKVGE--QALYLAQlkgmsERDAKDKIKYWFD------------KFEINS-----WYN-------KKVEELSKGM 137
Cdd:PRK11819 382 ------KIGEtvKLAYVDQ-----SRDALDPNKTVWEeisggldiikvgNREIPSrayvgRFNfkggdqqKKVGVLSGGE 450

                        170       180
                 ....*....|....*....|....*..
gi 256041152 138 QQKVQFISTIMHSPDLLILDEPFSGLD 164
Cdd:PRK11819 451 RNRLHLAKTLKQGGNVLLLDEPTNDLD 477
ABCC_MsbA cd03251
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ...
 4-209 2.99e-18

ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213218 [Multi-domain]  Cd Length: 234  Bit Score: 82.28  E-value: 2.99e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYATHK--AVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGrpfdpqTDIHAIGYmpe 81
Cdd:cd03251    1 VEFKNVTFRYPGDGppVLRDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDVDSGRILIDG------HDVRDYTL--- 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  82 eRGLYKKMKVGEQALYL-----AQLKGMSERDAKD-------KIKYWFDkF--EINSWYNKKVEE----LSKGMQQKVQF 143
Cdd:cd03251   72 -ASLRRQIGLVSQDVFLfndtvAENIAYGRPGATReeveeaaRAANAHE-FimELPEGYDTVIGErgvkLSGGQRQRIAI 149

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 256041152 144 ISTIMHSPDLLILDEPFSGLDPINANLIKQEIFDLSKNGTTIIFStHRMEQVEEIcDRIVLVNQGK 209
Cdd:cd03251  150 ARALLKDPPILILDEATSALDTESERLVQAALERLMKNRTTFVIA-HRLSTIENA-DRIVVLEDGK 213
YnjD COG4136
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ...
 19-165 3.08e-18

ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];


Pssm-ID: 443311 [Multi-domain]  Cd Length: 211  Bit Score: 81.37  E-value: 3.08e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  19 VDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPD---KGEILFNGRPFDP-QTDIHAIGYMPEERGLYKKMKVG-- 92
Cdd:COG4136   17 LAPLSLTVAPGEILTLMGPSGSGKSTLLAAIAGTLSPAfsaSGEVLLNGRRLTAlPAEQRRIGILFQDDLLFPHLSVGen 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  93 ------------------EQALYLAQLKGMSERDakdkikywfdkfeinswynkkVEELSKGMQQKVQFISTIMHSPDLL 154
Cdd:COG4136   97 lafalpptigraqrrarvEQALEEAGLAGFADRD---------------------PATLSGGQRARVALLRALLAEPRAL 155

                        170
                 ....*....|.
gi 256041152 155 ILDEPFSGLDP 165
Cdd:COG4136  156 LLDEPFSKLDA 166
cbiO PRK13650
energy-coupling factor transporter ATPase;
1-209 3.48e-18

energy-coupling factor transporter ATPase;


Pssm-ID: 184209 [Multi-domain]  Cd Length: 279  Bit Score: 82.86  E-value: 3.48e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   1 MNLIEIKHL---YKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPQT--DI-H 74
Cdd:PRK13650   2 SNIIEVKNLtfkYKEDQEKYTLNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIIDGDLLTEENvwDIrH 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  75 AIGYM---PEERglYKKMKVGEQALYLAQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSP 151
Cdd:PRK13650  82 KIGMVfqnPDNQ--FVGATVEDDVAFGLENKGIPHEEMKERVNEALELVGMQDFKEREPARLSGGQKQRVAIAGAVAMRP 159

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 256041152 152 DLLILDEPFSGLDPI-NANLIK--QEIFDlsKNGTTIIFSTHRMEQVeEICDRIVLVNQGK 209
Cdd:PRK13650 160 KIIILDEATSMLDPEgRLELIKtiKGIRD--DYQMTVISITHDLDEV-ALSDRVLVMKNGQ 217
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
 4-219 4.20e-18

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 84.47  E-value: 4.20e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152    4 IEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGI--FYPDKGEILFN----------------GR 65
Cdd:TIGR03269   1 IEVKNLTKKFDGKEVLKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGMdqYEPTSGRIIYHvalcekcgyverpskvGE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   66 P-------FDPQtDIHAIGYM-PEERGLYKKMKVGEQ---ALYLAQ------LKGMSE--RDAKDKIKYWFDKFEINSWY 126
Cdd:TIGR03269  81 PcpvcggtLEPE-EVDFWNLSdKLRRRIRKRIAIMLQrtfALYGDDtvldnvLEALEEigYEGKEAVGRAVDLIEMVQLS 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  127 NKKV---EELSKGMQQKVQFISTIMHSPDLLILDEPFSGLDPINANLIKQEIFDLSKN-GTTIIFSTHRMEQVEEICDRI 202
Cdd:TIGR03269 160 HRIThiaRDLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEAVKAsGISMVLTSHWPEVIEDLSDKA 239

                         250
                  ....*....|....*..
gi 256041152  203 VLvnqgkkLLDGEVKQI 219
Cdd:TIGR03269 240 IW------LENGEIKEE 250
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
 3-209 7.42e-18

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 83.92  E-value: 7.42e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   3 LIEIKHL-YKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRP---FDPQTDIHA-IG 77
Cdd:COG3845  257 VLEVENLsVRDDRGVPALKDVSLEVRAGEILGIAGVAGNGQSELAEALAGLRPPASGSIRLDGEDitgLSPRERRRLgVA 336

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  78 YMPEER---GLYKKMKVGEQALylaqlkgMSERDAKDKIKYWF-DKFEINSWYNKKVEE--------------LSKGMQQ 139
Cdd:COG3845  337 YIPEDRlgrGLVPDMSVAENLI-------LGRYRRPPFSRGGFlDRKAIRAFAEELIEEfdvrtpgpdtparsLSGGNQQ 409

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 140 KVQFISTIMHSPDLLILDEPFSGLDPINANLIKQEIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGK 209
Cdd:COG3845  410 KVILARELSRDPKLLIAAQPTRGLDVGAIEFIHQRLLELRDAGAAVLLISEDLDEILALSDRIAVMYEGR 479
CP_lyasePhnK TIGR02323
phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P ...
 3-222 7.79e-18

phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P lyase systems for utilization of phosphonates. These systems resemble phosphonatase-based systems in having a three component ABC transporter, where TIGR01097 is the permease, TIGR01098 is the phosphonates binding protein, and TIGR02315 is the ATP-binding cassette (ABC) protein. They differ, however, in having, typically, ten or more additional genes, many of which are believed to form a membrane-associated complex. This protein (PhnK) and the adjacent-encoded PhnL resemble transporter ATP-binding proteins but are suggested, based on mutatgenesis studies, to be part of this complex rather than part of a transporter per se. [Central intermediary metabolism, Phosphorus compounds]


Pssm-ID: 188208 [Multi-domain]  Cd Length: 253  Bit Score: 81.42  E-value: 7.79e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152    3 LIEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPqtdiHAIGYMPE- 81
Cdd:TIGR02323   3 LLQVSGLSKSYGGGKGCRDVSFDLYPGEVLGIVGESGSGKSTLLGCLAGRLAPDHGTATYIMRSGAE----LELYQLSEa 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   82 ER-----------------GLykKMKVGEQALYLAQLKGMSER---DAKDKIKYWFDKFEIN-SWYNKKVEELSKGMQQK 140
Cdd:TIGR02323  79 ERrrlmrtewgfvhqnprdGL--RMRVSAGANIGERLMAIGARhygNIRATAQDWLEEVEIDpTRIDDLPRAFSGGMQQR 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  141 VQFISTIMHSPDLLILDEPFSGLD-PINANLIkqeifDLSKN-----GTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDG 214
Cdd:TIGR02323 157 LQIARNLVTRPRLVFMDEPTGGLDvSVQARLL-----DLLRGlvrdlGLAVIIVTHDLGVARLLAQRLLVMQQGRVVESG 231


                  ....*...
gi 256041152  215 EVKQIKQD 222
Cdd:TIGR02323 232 LTDQVLDD 239
ugpC PRK11650
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
1-219 7.86e-18

sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;


Pssm-ID: 236947 [Multi-domain]  Cd Length: 356  Bit Score: 82.97  E-value: 7.86e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   1 MNLIEIKHLYKHY-ATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFdpqTDIHaigym 79
Cdd:PRK11650   1 MAGLKLQAVRKSYdGKTQVIKGIDLDVADGEFIVLVGPSGCGKSTLLRMVAGLERITSGEIWIGGRVV---NELE----- 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  80 PEERG---------LYKKMKVGEQALYLAQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHS 150
Cdd:PRK11650  73 PADRDiamvfqnyaLYPHMSVRENMAYGLKIRGMPKAEIEERVAEAARILELEPLLDRKPRELSGGQRQRVAMGRAIVRE 152

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 256041152 151 PDLLILDEPFSGLDpinANLIKQ---EIFDLSKN-GTTIIFSTHrmEQVE--EICDRIVLVNQgkklldGEVKQI 219
Cdd:PRK11650 153 PAVFLFDEPLSNLD---AKLRVQmrlEIQRLHRRlKTTSLYVTH--DQVEamTLADRVVVMNG------GVAEQI 216
PRK14243 PRK14243
phosphate transporter ATP-binding protein; Provisional
 3-206 8.24e-18

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184588 [Multi-domain]  Cd Length: 264  Bit Score: 81.37  E-value: 8.24e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   3 LIEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLR-------MITGifYPDKGEILFNGRP-FDPQTDIH 74
Cdd:PRK14243  10 VLRTENLNVYYGSFLAVKNVWLDIPKNQITAFIGPSGCGKSTILRcfnrlndLIPG--FRVEGKVTFHGKNlYAPDVDPV 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  75 A----IGYM-----PEERGLYKKMKVGEQAL-YLAQLKGMSERDAK-----DKIKywfDKFEINSwynkkvEELSKGMQQ 139
Cdd:PRK14243  88 EvrrrIGMVfqkpnPFPKSIYDNIAYGARINgYKGDMDELVERSLRqaalwDEVK---DKLKQSG------LSLSGGQQQ 158

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 256041152 140 KVQFISTIMHSPDLLILDEPFSGLDPINANLIKQEIFDLsKNGTTIIFSTHRMEQVEEICDRIVLVN 206
Cdd:PRK14243 159 RLCIARAIAVQPEVILMDEPCSALDPISTLRIEELMHEL-KEQYTIIIVTHNMQQAARVSDMTAFFN 224
PRK11000 PRK11000
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
1-209 9.57e-18

maltose/maltodextrin ABC transporter ATP-binding protein MalK;


Pssm-ID: 182893 [Multi-domain]  Cd Length: 369  Bit Score: 82.77  E-value: 9.57e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   1 MNLIEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDpqtDIHaigymP 80
Cdd:PRK11000   1 MASVTLRNVTKAYGDVVISKDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDITSGDLFIGEKRMN---DVP-----P 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  81 EERG---------LYKKMKVGEQALYLAQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSP 151
Cdd:PRK11000  73 AERGvgmvfqsyaLYPHLSVAENMSFGLKLAGAKKEEINQRVNQVAEVLQLAHLLDRKPKALSGGQRQRVAIGRTLVAEP 152

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 256041152 152 DLLILDEPFSGLDpinANLIKQ---EIFDLSKN-GTTIIFSTHrmEQVE--EICDRIVLVNQGK 209
Cdd:PRK11000 153 SVFLLDEPLSNLD---AALRVQmriEISRLHKRlGRTMIYVTH--DQVEamTLADKIVVLDAGR 211
cbiO PRK13648
cobalt transporter ATP-binding subunit; Provisional
 2-231 1.29e-17

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184207 [Multi-domain]  Cd Length: 269  Bit Score: 80.95  E-value: 1.29e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   2 NLIEIKHLYKHYATHKA--VDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPQ--TDIHA-I 76
Cdd:PRK13648   6 SIIVFKNVSFQYQSDASftLKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIFYNNQAITDDnfEKLRKhI 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  77 GYM---PEER--GLYKKMKVgeqALYLAQlKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSP 151
Cdd:PRK13648  86 GIVfqnPDNQfvGSIVKYDV---AFGLEN-HAVPYDEMHRRVSEALKQVDMLERADYEPNALSGGQKQRVAIAGVLALNP 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 152 DLLILDEPFSGLDPINanliKQEIFDL-----SKNGTTIIFSTHRMEQVEEiCDRIVLVNQGKKLLDGEVKQIKQDfKQH 226
Cdd:PRK13648 162 SVIILDEATSMLDPDA----RQNLLDLvrkvkSEHNITIISITHDLSEAME-ADHVIVMNKGTVYKEGTPTEIFDH-AEE 235


                 ....*
gi 256041152 227 LFRIG 231
Cdd:PRK13648 236 LTRIG 240
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
 21-209 1.45e-17

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 83.18  E-value: 1.45e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  21 DISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPF---DPQTDIHA-IGYMPEER---GLYKKMKVGE 93
Cdd:PRK15439 281 NISLEVRAGEILGLAGVVGAGRTELAETLYGLRPARGGRIMLNGKEInalSTAQRLARgLVYLPEDRqssGLYLDAPLAW 360

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  94 QALYLAQ-LKGMSERDAKDK-----------IKYwfdkfeinSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEPFS 161
Cdd:PRK15439 361 NVCALTHnRRGFWIKPARENavleryrralnIKF--------NHAEQAARTLSGGNQQKVLIAKCLEASPQLLIVDEPTR 432

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 256041152 162 GLDPINANLIKQEIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGK 209
Cdd:PRK15439 433 GVDVSARNDIYQLIRSIAAQNVAVLFISSDLEEIEQMADRVLVMHQGE 480
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
5-209 1.96e-17

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 82.52  E-value: 1.96e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   5 EIKHLYKHyaTHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPQTDIHA----IGYMP 80
Cdd:PRK09700 267 EVRNVTSR--DRKKVRDISFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRAGGEIRLNGKDISPRSPLDAvkkgMAYIT 344

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  81 EER---GLYKKMKVGE-----QALYLAQLKG-MSERDAKDKIKYWFDKFEINSW----YNKKVEELSKGMQQKVQFISTI 147
Cdd:PRK09700 345 ESRrdnGFFPNFSIAQnmaisRSLKDGGYKGaMGLFHEVDEQRTAENQRELLALkchsVNQNITELSGGNQQKVLISKWL 424

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 256041152 148 MHSPDLLILDEPFSGLDpINAnliKQEIF----DLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGK 209
Cdd:PRK09700 425 CCCPEVIIFDEPTRGID-VGA---KAEIYkvmrQLADDGKVILMVSSELPEIITVCDRIAVFCEGR 486
PRK03695 PRK03695
vitamin B12-transporter ATPase; Provisional
 22-219 3.99e-17

vitamin B12-transporter ATPase; Provisional


Pssm-ID: 235150 [Multi-domain]  Cd Length: 248  Bit Score: 79.21  E-value: 3.99e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  22 ISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFyPDKGEILFNGRPFD--PQTDI-HAIGYMPEERGLYKKMKVGeQALYL 98
Cdd:PRK03695  15 LSAEVRAGEILHLVGPNGAGKSTLLARMAGLL-PGSGSIQFAGQPLEawSAAELaRHRAYLSQQQTPPFAMPVF-QYLTL 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  99 AQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMH-SPD------LLILDEPFSGLDPINANLI 171
Cdd:PRK03695  93 HQPDKTRTEAVASALNEVAEALGLDDKLGRSVNQLSGGEWQRVRLAAVVLQvWPDinpagqLLLLDEPMNSLDVAQQAAL 172

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 256041152 172 KQEIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQI 219
Cdd:PRK03695 173 DRLLSELCQQGIAVVMSSHDLNHTLRHADRVWLLKQGKLLASGRRDEV 220
cbiO PRK13640
energy-coupling factor transporter ATPase;
2-219 6.17e-17

energy-coupling factor transporter ATPase;


Pssm-ID: 184200 [Multi-domain]  Cd Length: 282  Bit Score: 79.46  E-value: 6.17e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   2 NLIEIKHLYKHYATHK--AVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPD---KGEILFNGRPFDPQT--DIH 74
Cdd:PRK13640   4 NIVEFKHVSFTYPDSKkpALNDISFSIPRGSWTALIGHNGSGKSTISKLINGLLLPDdnpNSKITVDGITLTAKTvwDIR 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  75 -AIGYM---PEERglYKKMKVGEQALYLAQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHS 150
Cdd:PRK13640  84 eKVGIVfqnPDNQ--FVGATVGDDVAFGLENRAVPRPEMIKIVRDVLADVGMLDYIDSEPANLSGGQKQRVAIAGILAVE 161

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 151 PDLLILDEPFSGLDPINANLIKQEIFDLSK-NGTTIIFSTHRMEQVeEICDRIVLVNQGKKLLDGEVKQI 219
Cdd:PRK13640 162 PKIIILDESTSMLDPAGKEQILKLIRKLKKkNNLTVISITHDIDEA-NMADQVLVLDDGKLLAQGSPVEI 230
3a01204 TIGR00955
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ...
 21-230 6.31e-17

The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273361 [Multi-domain]  Cd Length: 617  Bit Score: 81.25  E-value: 6.31e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   21 DISFAIPKGSIFGLLGPNGAGKTTLL-----RMITGIFYpdKGEILFNGRPFDPQtDIHAI-GYMPEERGLYKKMKVGEQ 94
Cdd:TIGR00955  43 NVSGVAKPGELLAVMGSSGAGKTTLMnalafRSPKGVKG--SGSVLLNGMPIDAK-EMRAIsAYVQQDDLFIPTLTVREH 119

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   95 ALYLAQLKgMSERDAKDKIKYWFD------------KFEINSWYNKKVeeLSKGMQQKVQFISTIMHSPDLLILDEPFSG 162
Cdd:TIGR00955 120 LMFQAHLR-MPRRVTKKEKRERVDevlqalglrkcaNTRIGVPGRVKG--LSGGERKRLAFASELLTDPPLLFCDEPTSG 196

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 256041152  163 LDPINANLIKQEIFDLSKNGTTIIFSTHR-MEQVEEICDRIVLVNQGKKLLDGEVKQIKQDFKQHLFRI 230
Cdd:TIGR00955 197 LDSFMAYSVVQVLKGLAQKGKTIICTIHQpSSELFELFDKIILMAEGRVAYLGSPDQAVPFFSDLGHPC 265
cbiO PRK13638
energy-coupling factor ABC transporter ATP-binding protein;
9-215 8.31e-17

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184198 [Multi-domain]  Cd Length: 271  Bit Score: 78.90  E-value: 8.31e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   9 LYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFD--------PQTDIHAIGYMP 80
Cdd:PRK13638   7 LWFRYQDEPVLKGLNLDFSLSPVTGLVGANGCGKSTLFMNLSGLLRPQKGAVLWQGKPLDyskrgllaLRQQVATVFQDP 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  81 EERGLYKKMKvGEQALYLAQLkGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEPF 160
Cdd:PRK13638  87 EQQIFYTDID-SDIAFSLRNL-GVPEAEITRRVDEALTLVDAQHFRHQPIQCLSHGQKKRVAIAGALVLQARYLLLDEPT 164

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 256041152 161 SGLDPINANLIKQEIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGE 215
Cdd:PRK13638 165 AGLDPAGRTQMIAIIRRIVAQGNHVIISSHDIDLIYEISDAVYVLRQGQILTHGA 219
PRK14246 PRK14246
phosphate ABC transporter ATP-binding protein; Provisional
 2-227 8.37e-17

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172734 [Multi-domain]  Cd Length: 257  Bit Score: 78.55  E-value: 8.37e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   2 NLIEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGI--FYPDK----GEILFNGRP---FDPQTD 72
Cdd:PRK14246   9 DVFNISRLYLYINDKAILKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLieIYDSKikvdGKVLYFGKDifqIDAIKL 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  73 IHAIGYMPEERGLYKKMKVGEQALYLAQLKGMSE-RDAKDKIKYWFDKF----EINSWYNKKVEELSKGMQQKVQFISTI 147
Cdd:PRK14246  89 RKEVGMVFQQPNPFPHLSIYDNIAYPLKSHGIKEkREIKKIVEECLRKVglwkEVYDRLNSPASQLSGGQQQRLTIARAL 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 148 MHSPDLLILDEPFSGLDPINANLIKQEIFDLsKNGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQIKQDFKQHL 227
Cdd:PRK14246 169 ALKPKVLLMDEPTSMIDIVNSQAIEKLITEL-KNEIAIVIVSHNPQQVARVADYVAFLYNGELVEWGSSNEIFTSPKNEL 247
PRK13633 PRK13633
energy-coupling factor transporter ATPase;
2-234 9.15e-17

energy-coupling factor transporter ATPase;


Pssm-ID: 237453 [Multi-domain]  Cd Length: 280  Bit Score: 78.98  E-value: 9.15e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   2 NLIEIKHLYKHYA------THKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGrpFDpQTDIHA 75
Cdd:PRK13633   3 EMIKCKNVSYKYEsneestEKLALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKVYVDG--LD-TSDEEN 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  76 IGYMPEERGLYKKMK--------VGEQALYLAQLKGMSERDAKDKIKYWFDKfeINSWYNKKVEE--LSKGMQQKVQFIS 145
Cdd:PRK13633  80 LWDIRNKAGMVFQNPdnqivatiVEEDVAFGPENLGIPPEEIRERVDESLKK--VGMYEYRRHAPhlLSGGQKQRVAIAG 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 146 TIMHSPDLLILDEPFSGLDPINANLIKQEIFDLSKN-GTTIIFSTHRMEQVEEiCDRIVLVNQGKKLLDGEVKQIkqdFK 224
Cdd:PRK13633 158 ILAMRPECIIFDEPTAMLDPSGRREVVNTIKELNKKyGITIILITHYMEEAVE-ADRIIVMDSGKVVMEGTPKEI---FK 233

                        250
                 ....*....|..
gi 256041152 225 Q--HLFRIGFGV 234
Cdd:PRK13633 234 EveMMKKIGLDV 245
PRK13540 PRK13540
cytochrome c biogenesis protein CcmA; Provisional
 1-191 9.50e-17

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 184127 [Multi-domain]  Cd Length: 200  Bit Score: 77.30  E-value: 9.50e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   1 MNLIEIKHlykHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPQ--TDIHAIGY 78
Cdd:PRK13540   2 LDVIELDF---DYHDQPLLQQISFHLPAGGLLHLKGSNGAGKTTLLKLIAGLLNPEKGEILFERQSIKKDlcTYQKQLCF 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  79 MPEERGLYKKMKVGEQALY-LAQLKGMSERDAKDKIkywfdkFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILD 157
Cdd:PRK13540  79 VGHRSGINPYLTLRENCLYdIHFSPGAVGITELCRL------FSLEHLIDYPCGLLSSGQKRQVALLRLWMSKAKLWLLD 152

                        170       180       190
                 ....*....|....*....|....*....|....
gi 256041152 158 EPFSGLDPINANLIKQEIFDLSKNGTTIIFSTHR 191
Cdd:PRK13540 153 EPLVALDELSLLTIITKIQEHRAKGGAVLLTSHQ 186
cbiO PRK13634
cobalt transporter ATP-binding subunit; Provisional
 17-234 1.83e-16

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237454 [Multi-domain]  Cd Length: 290  Bit Score: 78.14  E-value: 1.83e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  17 KAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPQTDihaigympeERGLYK-KMKVG--- 92
Cdd:PRK13634  21 RALYDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVTIGERVITAGKK---------NKKLKPlRKKVGivf 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  93 ---EQALYLAQLK----------GMSERDAKDKIKYWFDKFEIN-SWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDE 158
Cdd:PRK13634  92 qfpEHQLFEETVEkdicfgpmnfGVSEEDAKQKAREMIELVGLPeELLARSPFELSGGQMRRVAIAGVLAMEPEVLVLDE 171

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 256041152 159 PFSGLDPINANLIKQEIFDLSK-NGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQIKQDfKQHLFRIGFGV 234
Cdd:PRK13634 172 PTAGLDPKGRKEMMEMFYKLHKeKGLTTVLVTHSMEDAARYADQIVVMHKGTVFLQGTPREIFAD-PDELEAIGLDL 247
PRK11160 PRK11160
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
 3-209 2.36e-16

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236865 [Multi-domain]  Cd Length: 574  Bit Score: 79.48  E-value: 2.36e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   3 LIEIKHLYKHY--ATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPfdpqtdIHAIGymp 80
Cdd:PRK11160 338 SLTLNNVSFTYpdQPQPVLKGLSLQIKAGEKVALLGRTGCGKSTLLQLLTRAWDPQQGEILLNGQP------IADYS--- 408

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  81 eERGLYKKMKVGEQALYL------------------AQLKGMSERDAKDKIkywFDKFE-INSWYNKKVEELSKGMQQKV 141
Cdd:PRK11160 409 -EAALRQAISVVSQRVHLfsatlrdnlllaapnasdEALIEVLQQVGLEKL---LEDDKgLNAWLGEGGRQLSGGEQRRL 484

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 256041152 142 QFISTIMHSPDLLILDEPFSGLDPINANLIKQEIFDLSKNgTTIIFSTHR---MEQVeeicDRIVLVNQGK 209
Cdd:PRK11160 485 GIARALLHDAPLLLLDEPTEGLDAETERQILELLAEHAQN-KTVLMITHRltgLEQF----DRICVMDNGQ 550
ArpD COG4618
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ...
 19-209 2.51e-16

ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 443660 [Multi-domain]  Cd Length: 563  Bit Score: 79.41  E-value: 2.51e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  19 VDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFD--PQTDIH-AIGYMPEERGLYK-------- 87
Cdd:COG4618  348 LRGVSFSLEPGEVLGVIGPSGSGKSTLARLLVGVWPPTAGSVRLDGADLSqwDREELGrHIGYLPQDVELFDgtiaenia 427

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  88 KM------KVGEqAlylAQLKGMSERdakdkikywfdkfeINSW---YNKKVEE----LSKGMQQKVQFISTIMHSPDLL 154
Cdd:COG4618  428 RFgdadpeKVVA-A---AKLAGVHEM--------------ILRLpdgYDTRIGEggarLSGGQRQRIGLARALYGDPRLV 489

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 256041152 155 ILDEPfsgldpiNANL-------IKQEIFDLSKNGTTIIFSTHRMeQVEEICDRIVLVNQGK 209
Cdd:COG4618  490 VLDEP-------NSNLddegeaaLAAAIRALKARGATVVVITHRP-SLLAAVDKLLVLRDGR 543
ABCC_MRP_domain1 cd03250
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ...
 4-209 2.59e-16

ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213217 [Multi-domain]  Cd Length: 204  Bit Score: 75.97  E-value: 2.59e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLY-----KHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRpfdpqtdihaIGY 78
Cdd:cd03250    1 ISVEDASftwdsGEQETSFTLKDINLEVPKGELVAIVGPVGSGKSSLLSALLGELEKLSGSVSVPGS----------IAY 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  79 MP---------------------EERglYKKmkvgeqALYLAQLkgmsERDakdkikywFDKFE-----------INswy 126
Cdd:cd03250   71 VSqepwiqngtirenilfgkpfdEER--YEK------VIKACAL----EPD--------LEILPdgdlteigekgIN--- 127

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 127 nkkveeLSKGMQQKVQFISTIMHSPDLLILDEPFSGLDP-INANLIKQEIFDLSKNGTTIIFSTHRMEQVEEiCDRIVLV 205
Cdd:cd03250  128 ------LSGGQKQRISLARAVYSDADIYLLDDPLSAVDAhVGRHIFENCILGLLLNNKTRILVTHQLQLLPH-ADQIVVL 200


                 ....
gi 256041152 206 NQGK 209
Cdd:cd03250  201 DNGR 204
GguA NF040905
sugar ABC transporter ATP-binding protein;
3-216 2.98e-16

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 79.06  E-value: 2.98e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   3 LIEIKHLYKHYATH---KAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDK--GEILFNGRPFDPQTDIHAIG 77
Cdd:NF040905 257 VFEVKNWTVYHPLHperKVVDDVSLNVRRGEIVGIAGLMGAGRTELAMSVFGRSYGRNisGTVFKDGKEVDVSTVSDAID 336

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  78 ----YMPEER---GLYKKMKVGEQaLYLAQLKGMSERDAKDKIKywfdKFEINSWYNKK-----------VEELSKGMQQ 139
Cdd:NF040905 337 aglaYVTEDRkgyGLNLIDDIKRN-ITLANLGKVSRRGVIDENE----EIKVAEEYRKKmniktpsvfqkVGNLSGGNQQ 411

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 140 KVQFISTIMHSPDLLILDEPFSGLDpINAnliKQEIF----DLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGKklLDGE 215
Cdd:NF040905 412 KVVLSKWLFTDPDVLILDEPTRGID-VGA---KYEIYtiinELAAEGKGVIVISSELPELLGMCDRIYVMNEGR--ITGE 485


                 .
gi 256041152 216 V 216
Cdd:NF040905 486 L 486
PRK13539 PRK13539
cytochrome c biogenesis protein CcmA; Provisional
 21-190 3.60e-16

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 237421 [Multi-domain]  Cd Length: 207  Bit Score: 75.68  E-value: 3.60e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  21 DISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPQTDIHAIGYMPEERGLYKKMKVGEQALYLAQ 100
Cdd:PRK13539  20 GLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLDGGDIDDPDVAEACHYLGHRNAMKPALTVAENLEFWAA 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 101 LKGMSERDAKDKIkywfDKFEINSWYNKKVEELSKGMQQKVQFIS-TIMHSPdLLILDEPFSGLDPINANLIKQEIFDLS 179
Cdd:PRK13539 100 FLGGEELDIAAAL----EAVGLAPLAHLPFGYLSAGQKRRVALARlLVSNRP-IWILDEPTAALDAAAVALFAELIRAHL 174

                        170
                 ....*....|.
gi 256041152 180 KNGTTIIFSTH 190
Cdd:PRK13539 175 AQGGIVIAATH 185
PRK14267 PRK14267
phosphate ABC transporter ATP-binding protein; Provisional
 1-227 3.71e-16

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184596 [Multi-domain]  Cd Length: 253  Bit Score: 76.80  E-value: 3.71e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   1 MNLIEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPD-----KGEILFNGR-----PFDPQ 70
Cdd:PRK14267   2 KFAIETVNLRVYYGSNHVIKGVDLKIPQNGVFALMGPSGCGKSTLLRTFNRLLELNeearvEGEVRLFGRniyspDVDPI 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  71 TDIHAIGYMPEERGLYKKMKVGEQALYLAQLKGMSE-RDAKDKIKYWFDKF-----EINSWYNKKVEELSKGMQQKVQFI 144
Cdd:PRK14267  82 EVRREVGMVFQYPNPFPHLTIYDNVAIGVKLNGLVKsKKELDERVEWALKKaalwdEVKDRLNDYPSNLSGGQRQRLVIA 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 145 STIMHSPDLLILDEPFSGLDPINANLIKQEIFDLsKNGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQIKQDFK 224
Cdd:PRK14267 162 RALAMKPKILLMDEPTANIDPVGTAKIEELLFEL-KKEYTIVLVTHSPAQAARVSDYVAFLYLGKLIEVGPTRKVFENPE 240


                 ...
gi 256041152 225 QHL 227
Cdd:PRK14267 241 HEL 243
ssuB PRK11247
aliphatic sulfonates transport ATP-binding subunit; Provisional
 6-213 4.64e-16

aliphatic sulfonates transport ATP-binding subunit; Provisional


Pssm-ID: 183055 [Multi-domain]  Cd Length: 257  Bit Score: 76.64  E-value: 4.64e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   6 IKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPF-DPQTDIHaigYMPEERG 84
Cdd:PRK11247  15 LNAVSKRYGERTVLNQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLETPSAGELLAGTAPLaEAREDTR---LMFQDAR 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  85 L--YKKM--KVG--------EQALYLAQLKGMSERdakdkikywfdkfeINSWynkkVEELSKGMQQKVQFISTIMHSPD 152
Cdd:PRK11247  92 LlpWKKVidNVGlglkgqwrDAALQALAAVGLADR--------------ANEW----PAALSGGQKQRVALARALIHRPG 153

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 256041152 153 LLILDEPFSGLDPINANLIKQEIFDL-SKNGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLD 213
Cdd:PRK11247 154 LLLLDEPLGALDALTRIEMQDLIESLwQQHGFTVLLVTHDVSEAVAMADRVLLIEEGKIGLD 215
MK0520 COG2401
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ...
 15-208 5.27e-16

ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];


Pssm-ID: 441957 [Multi-domain]  Cd Length: 222  Bit Score: 75.77  E-value: 5.27e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  15 THKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGI--FYPDKGEILFNGRPFDPQT----DIHAIGYMPEERGLYKK 88
Cdd:COG2401   42 ERYVLRDLNLEIEPGEIVLIVGASGSGKSTLLRLLAGAlkGTPVAGCVDVPDNQFGREAslidAIGRKGDFKDAVELLNA 121

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  89 MKVGEQALYLAqlkgmserdakdkikywfdkfeinswynkKVEELSKGMQQKVQFISTIMHSPDLLILDEPFSGLDPINA 168
Cdd:COG2401  122 VGLSDAVLWLR-----------------------------RFKELSTGQKFRFRLALLLAERPKLLVIDEFCSHLDRQTA 172

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 256041152 169 NLIKQEIFDLS-KNGTTIIFSTHRMEQVEEIC-DRIVLVNQG 208
Cdd:COG2401  173 KRVARNLQKLArRAGITLVVATHHYDVIDDLQpDLLIFVGYG 214
cbiO PRK13649
energy-coupling factor transporter ATPase;
17-222 5.63e-16

energy-coupling factor transporter ATPase;


Pssm-ID: 184208 [Multi-domain]  Cd Length: 280  Bit Score: 76.71  E-value: 5.63e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  17 KAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPQT---DIHAIG-------YMPE----E 82
Cdd:PRK13649  21 RALFDVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVRVDDTLITSTSknkDIKQIRkkvglvfQFPEsqlfE 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  83 RGLYKKMKVGEQALYLAQLKgmSERDAKDKIKYWFDKFEInswYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEPFSG 162
Cdd:PRK13649 101 ETVLKDVAFGPQNFGVSQEE--AEALAREKLALVGISESL---FEKNPFELSGGQMRRVAIAGILAMEPKILVLDEPTAG 175

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 256041152 163 LDPINanliKQEIFDLSK----NGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQIKQD 222
Cdd:PRK13649 176 LDPKG----RKELMTLFKklhqSGMTIVLVTHLMDDVANYADFVYVLEKGKLVLSGKPKDIFQD 235
oppD PRK09473
oligopeptide transporter ATP-binding component; Provisional
 1-231 5.63e-16

oligopeptide transporter ATP-binding component; Provisional


Pssm-ID: 181888 [Multi-domain]  Cd Length: 330  Bit Score: 77.07  E-value: 5.63e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   1 MNLIEIKHLYKHYATHK----AVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPD---KGEILFNGRPF------ 67
Cdd:PRK09473  10 DALLDVKDLRVTFSTPDgdvtAVNDLNFSLRAGETLGIVGESGSGKSQTAFALMGLLAANgriGGSATFNGREIlnlpek 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  68 ---------------DPQTDihaigympeergLYKKMKVGEQALYLAQL-KGMSERDAKDKIKYWFDKFEINSwYNKKV- 130
Cdd:PRK09473  90 elnklraeqismifqDPMTS------------LNPYMRVGEQLMEVLMLhKGMSKAEAFEESVRMLDAVKMPE-ARKRMk 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 131 ---EELSKGMQQKVQFISTIMHSPDLLILDEPFSGLD-PINA------NLIKQEIfdlsknGTTIIFSTHRMEQVEEICD 200
Cdd:PRK09473 157 mypHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDvTVQAqimtllNELKREF------NTAIIMITHDLGVVAGICD 230

                        250       260       270
                 ....*....|....*....|....*....|...
gi 256041152 201 RIVLVNQGKKLLDGEVKQIkqdFKQ--HLFRIG 231
Cdd:PRK09473 231 KVLVMYAGRTMEYGNARDV---FYQpsHPYSIG 260
PRK13657 PRK13657
glucan ABC transporter ATP-binding protein/ permease;
18-209 6.08e-16

glucan ABC transporter ATP-binding protein/ permease;


Pssm-ID: 184214 [Multi-domain]  Cd Length: 588  Bit Score: 78.46  E-value: 6.08e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  18 AVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGrpfdpqTDI---------HAIGYMPEERGLYKK 88
Cdd:PRK13657 350 GVEDVSFEAKPGQTVAIVGPTGAGKSTLINLLQRVFDPQSGRILIDG------TDIrtvtraslrRNIAVVFQDAGLFNR 423

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  89 -----MKVGEQALYLAQLKGMSER-DAKDKIKYWFDKFEINswynkkVEE----LSKGMQQKVQFISTIMHSPDLLILDE 158
Cdd:PRK13657 424 siednIRVGRPDATDEEMRAAAERaQAHDFIERKPDGYDTV------VGErgrqLSGGERQRLAIARALLKDPPILILDE 497

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 256041152 159 PFSGLDPINANLIKQEIFDLSKNGTTIIFStHRMEQVEEiCDRIVLVNQGK 209
Cdd:PRK13657 498 ATSALDVETEAKVKAALDELMKGRTTFIIA-HRLSTVRN-ADRILVFDNGR 546
PRK10247 PRK10247
putative ABC transporter ATP-binding protein YbbL; Provisional
 2-215 6.20e-16

putative ABC transporter ATP-binding protein YbbL; Provisional


Pssm-ID: 182331 [Multi-domain]  Cd Length: 225  Bit Score: 75.52  E-value: 6.20e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   2 NLIEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGrpfdpqTDIHAigYMPE 81
Cdd:PRK10247   6 PLLQLQNVGYLAGDAKILNNISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTLLFEG------EDIST--LKPE 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  82 ErglYKKmkvgeQALYLAQ---LKGMSERD-------------AKDKIKYWFDKFEI-NSWYNKKVEELSKGMQQKVQFI 144
Cdd:PRK10247  78 I---YRQ-----QVSYCAQtptLFGDTVYDnlifpwqirnqqpDPAIFLDDLERFALpDTILTKNIAELSGGEKQRISLI 149

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 256041152 145 STIMHSPDLLILDEPFSGLDPINANLIKQEIFDLSKN-GTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGE 215
Cdd:PRK10247 150 RNLQFMPKVLLLDEITSALDESNKHNVNEIIHRYVREqNIAVLWVTHDKDEINHADKVITLQPHAGEMQEAR 221
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
 3-222 7.39e-16

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 77.74  E-value: 7.39e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   3 LIEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRP--FD-PQTDIHA-IGY 78
Cdd:PRK10762   4 LLQLKGIDKAFPGVKALSGAALNVYPGRVMALVGENGAGKSTMMKVLTGIYTRDAGSILYLGKEvtFNgPKSSQEAgIGI 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  79 MPEERGLYKKMKVGEQaLYLA----------QLKGM-SERD---AKDKIKYwfdkfeiNSwyNKKVEELSKGMQQKVQFI 144
Cdd:PRK10762  84 IHQELNLIPQLTIAEN-IFLGrefvnrfgriDWKKMyAEADkllARLNLRF-------SS--DKLVGELSIGEQQMVEIA 153

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 256041152 145 STIMHSPDLLILDEPFSGL-DPINANLIKQeIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQIKQD 222
Cdd:PRK10762 154 KVLSFESKVIIMDEPTDALtDTETESLFRV-IRELKSQGRGIVYISHRLKEIFEICDDVTVFRDGQFIAEREVADLTED 231
cbiO PRK13643
energy-coupling factor transporter ATPase;
17-222 7.40e-16

energy-coupling factor transporter ATPase;


Pssm-ID: 184203 [Multi-domain]  Cd Length: 288  Bit Score: 76.31  E-value: 7.40e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  17 KAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNG---------RPFDPQTDIHAIGYMPEERGLYK 87
Cdd:PRK13643  20 RALFDIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKVTVGDivvsstskqKEIKPVRKKVGVVFQFPESQLFE 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  88 KMKVGEQAlYLAQLKGMSERDAKdkiKYWFDKFEI----NSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEPFSGL 163
Cdd:PRK13643 100 ETVLKDVA-FGPQNFGIPKEKAE---KIAAEKLEMvglaDEFWEKSPFELSGGQMRRVAIAGILAMEPEVLVLDEPTAGL 175

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 164 DPiNANLIKQEIFD-LSKNGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQIKQD 222
Cdd:PRK13643 176 DP-KARIEMMQLFEsIHQSGQTVVLVTHLMDDVADYADYVYLLEKGHIISCGTPSDVFQE 234
thiQ PRK10771
thiamine ABC transporter ATP-binding protein ThiQ;
3-215 7.94e-16

thiamine ABC transporter ATP-binding protein ThiQ;


Pssm-ID: 182716 [Multi-domain]  Cd Length: 232  Bit Score: 75.39  E-value: 7.94e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   3 LIEIKHLYKHYATHkavddISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNG----------RPfdpqtd 72
Cdd:PRK10771   4 LTDITWLYHHLPMR-----FDLTVERGERVAILGPSGAGKSTLLNLIAGFLTPASGSLTLNGqdhtttppsrRP------ 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  73 ihaIGYMPEERGLYKKMKVgEQALYLAQLKGMS-ERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSP 151
Cdd:PRK10771  73 ---VSMLFQENNLFSHLTV-AQNIGLGLNPGLKlNAAQREKLHAIARQMGIEDLLARLPGQLSGGQRQRVALARCLVREQ 148

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 256041152 152 DLLILDEPFSGLDPInanlIKQEIFDL-----SKNGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGE 215
Cdd:PRK10771 149 PILLLDEPFSALDPA----LRQEMLTLvsqvcQERQLTLLMVSHSLEDAARIAPRSLVVADGRIAWDGP 213
PRK15079 PRK15079
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
 3-205 8.19e-16

oligopeptide ABC transporter ATP-binding protein OppF; Provisional


Pssm-ID: 185037 [Multi-domain]  Cd Length: 331  Bit Score: 76.67  E-value: 8.19e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   3 LIEIKHLYKHY-------------ATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPF-- 67
Cdd:PRK15079   8 LLEVADLKVHFdikdgkqwfwqppKTLKAVDGVTLRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGEVAWLGKDLlg 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  68 -------DPQTDIHAIGYMPEErGLYKKMKVGE---QALYLAQLKgMSERDAKDKIKYWFDKFEI-NSWYNKKVEELSKG 136
Cdd:PRK15079  88 mkddewrAVRSDIQMIFQDPLA-SLNPRMTIGEiiaEPLRTYHPK-LSRQEVKDRVKAMMLKVGLlPNLINRYPHEFSGG 165

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 256041152 137 MQQKVQFISTIMHSPDLLILDEPFSGLD-PINA---NLIKQeifdLSKN-GTTIIFSTHRMEQVEEICDRiVLV 205
Cdd:PRK15079 166 QCQRIGIARALILEPKLIICDEPVSALDvSIQAqvvNLLQQ----LQREmGLSLIFIAHDLAVVKHISDR-VLV 234
phnK PRK11701
phosphonate C-P lyase system protein PhnK; Provisional
 3-164 8.78e-16

phosphonate C-P lyase system protein PhnK; Provisional


Pssm-ID: 183280 [Multi-domain]  Cd Length: 258  Bit Score: 75.73  E-value: 8.78e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   3 LIEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPQtDIHAIGyMPEE 82
Cdd:PRK11701   6 LLSVRGLTKLYGPRKGCRDVSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDAGEVHYRMRDGQLR-DLYALS-EAER 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  83 RGLYK--------------KMKV------GEqalylaQLKGMSER---DAKDKIKYWFDKFEINSwynKKVEEL----SK 135
Cdd:PRK11701  84 RRLLRtewgfvhqhprdglRMQVsaggniGE------RLMAVGARhygDIRATAGDWLERVEIDA---ARIDDLpttfSG 154

                        170       180
                 ....*....|....*....|....*....
gi 256041152 136 GMQQKVQFISTIMHSPDLLILDEPFSGLD 164
Cdd:PRK11701 155 GMQQRLQIARNLVTHPRLVFMDEPTGGLD 183
znuC PRK09544
high-affinity zinc transporter ATPase; Reviewed
 1-207 1.15e-15

high-affinity zinc transporter ATPase; Reviewed


Pssm-ID: 181939 [Multi-domain]  Cd Length: 251  Bit Score: 75.15  E-value: 1.15e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   1 MNLIEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILfngrpfdpQTDIHAIGYMP 80
Cdd:PRK09544   2 TSLVSLENVSVSFGQRRVLSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGVIK--------RNGKLRIGYVP 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  81 EERGLykkmkvgEQALYLAQLKGMSERDA--KDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDE 158
Cdd:PRK09544  74 QKLYL-------DTTLPLTVNRFLRLRPGtkKEDILPALKRVQAGHLIDAPMQKLSGGETQRVLLARALLNRPQLLVLDE 146

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 256041152 159 PFSGLDpINANLIKQEIFDLSKN--GTTIIFSTHRMEQVEEICDRIVLVNQ 207
Cdd:PRK09544 147 PTQGVD-VNGQVALYDLIDQLRRelDCAVLMVSHDLHLVMAKTDEVLCLNH 196
PLN03211 PLN03211
ABC transporter G-25; Provisional
 29-236 1.38e-15

ABC transporter G-25; Provisional


Pssm-ID: 215634 [Multi-domain]  Cd Length: 659  Bit Score: 77.23  E-value: 1.38e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  29 GSIFGLLGPNGAGKTTLLRMITGIFYPD--KGEILFNGRPFDPQTdIHAIGYMPEERGLYKKMKVGEQALYLAQLKGMSE 106
Cdd:PLN03211  94 GEILAVLGPSGSGKSTLLNALAGRIQGNnfTGTILANNRKPTKQI-LKRTGFVTQDDILYPHLTVRETLVFCSLLRLPKS 172

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 107 RDAKDKI--------KYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEPFSGLDPINANLIKQEIFDL 178
Cdd:PLN03211 173 LTKQEKIlvaesvisELGLTKCENTIIGNSFIRGISGGERKRVSIAHEMLINPSLLILDEPTSGLDATAAYRLVLTLGSL 252

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 256041152 179 SKNGTTIIFSTHR-MEQVEEICDRIVLVNQGKKLLDGEVKQIKQDFKQHLFRIGFGVMP 236
Cdd:PLN03211 253 AQKGKTIVTSMHQpSSRVYQMFDSVLVLSEGRCLFFGKGSDAMAYFESVGFSPSFPMNP 311
PRK10575 PRK10575
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
22-246 1.46e-15

Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;


Pssm-ID: 182561 [Multi-domain]  Cd Length: 265  Bit Score: 75.21  E-value: 1.46e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  22 ISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRP---FDPQTDIHAIGYMPEERGLYKKMKVGE----- 93
Cdd:PRK10575  30 LSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPlesWSSKAFARKVAYLPQQLPAAEGMTVRElvaig 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  94 -----QALylaqlkGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEPFSGLDPINA 168
Cdd:PRK10575 110 rypwhGAL------GRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQ 183

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 169 NLIKQEIFDLSK-NGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQIKQ-DFKQHLFRIGFGVMPNFAQVATHHF 246
Cdd:PRK10575 184 VDVLALVHRLSQeRGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAELMRgETLEQIYGIPMGILPHPAGAAPVSF 263
PRK10982 PRK10982
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
 3-209 1.49e-15

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional


Pssm-ID: 182880 [Multi-domain]  Cd Length: 491  Bit Score: 77.08  E-value: 1.49e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   3 LIEIKHLYKhyATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPQTDIHAI----GY 78
Cdd:PRK10982 250 ILEVRNLTS--LRQPSIRDVSFDLHKGEILGIAGLVGAKRTDIVETLFGIREKSAGTITLHGKKINNHNANEAInhgfAL 327

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  79 MPEER---GLYKKMKVGEQAL------YLAQLKGMSERDAKDKIKYWFDKFEINS-WYNKKVEELSKGMQQKVQFISTIM 148
Cdd:PRK10982 328 VTEERrstGIYAYLDIGFNSLisnirnYKNKVGLLDNSRMKSDTQWVIDSMRVKTpGHRTQIGSLSGGNQQKVIIGRWLL 407

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 256041152 149 HSPDLLILDEPFSGLDPINANLIKQEIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGK 209
Cdd:PRK10982 408 TQPEILMLDEPTRGIDVGAKFEIYQLIAELAKKDKGIIIISSEMPELLGITDRILVMSNGL 468
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
 1-228 2.65e-15

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 76.26  E-value: 2.65e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   1 MNLIEIKHLYKHYATHK----AVDDISFAIPKGSIFGLLGPNGAGKT----TLLRMITGIFYPDKGEILFNGRpfdpqtD 72
Cdd:COG4172    4 MPLLSVEDLSVAFGQGGgtveAVKGVSFDIAAGETLALVGESGSGKSvtalSILRLLPDPAAHPSGSILFDGQ------D 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  73 IHAigyMPEE-----RG-------------LYKKMKVGEQ-ALYLAQLKGMSERDAKDKIKYWFDKFEIN------SWYN 127
Cdd:COG4172   78 LLG---LSERelrriRGnriamifqepmtsLNPLHTIGKQiAEVLRLHRGLSGAAARARALELLERVGIPdperrlDAYP 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 128 kkvEELSKGMQQKVQFISTIMHSPDLLILDEPFSGLDPInanlIKQEIFDL-----SKNGTTIIFSTHRMEQVEEICDRI 202
Cdd:COG4172  155 ---HQLSGGQRQRVMIAMALANEPDLLIADEPTTALDVT----VQAQILDLlkdlqRELGMALLLITHDLGVVRRFADRV 227

                        250       260       270
                 ....*....|....*....|....*....|
gi 256041152 203 VLVNQGKKLLDGEVKQI----KQDFKQHLF 228
Cdd:COG4172  228 AVMRQGEIVEQGPTAELfaapQHPYTRKLL 257
CydC TIGR02868
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ...
 4-191 3.56e-15

thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.


Pssm-ID: 274331 [Multi-domain]  Cd Length: 530  Bit Score: 75.86  E-value: 3.56e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152    4 IEIKHLYKHYATHKAV-DDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFD--PQTDIHA-IGYM 79
Cdd:TIGR02868 335 LELRDLSAGYPGAPPVlDGVSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPLQGEVTLDGVPVSslDQDEVRRrVSVC 414

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   80 PEERGLYKKmKVGEQaLYLAQlKGMSERDAKD-----KIKYWFDkfEINSWYNKKVEE----LSKGMQQKVQFISTIMHS 150
Cdd:TIGR02868 415 AQDAHLFDT-TVREN-LRLAR-PDATDEELWAalervGLADWLR--ALPDGLDTVLGEggarLSGGERQRLALARALLAD 489

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 256041152  151 PDLLILDEPFSGLDPINANLIKQEIFDLSKnGTTIIFSTHR 191
Cdd:TIGR02868 490 APILLLDEPTEHLDAETADELLEDLLAALS-GRTVVLITHH 529
ABCD_peroxisomal_ALDP cd03223
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ...
 19-191 7.28e-15

ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).


Pssm-ID: 213190 [Multi-domain]  Cd Length: 166  Bit Score: 71.03  E-value: 7.28e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  19 VDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIfYPdkgeiLFNGRpfdpqtdIHaigyMPEerglykkmkvGEQALYL 98
Cdd:cd03223   17 LKDLSFEIKPGDRLLITGPSGTGKSSLFRALAGL-WP-----WGSGR-------IG----MPE----------GEDLLFL 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  99 AQLKGMSERDAKDKIKY-WFDkfeinswynkkveELSKGMQQKVQFISTIMHSPDLLILDEPFSGLDPINANLIKQEifd 177
Cdd:cd03223   70 PQRPYLPLGTLREQLIYpWDD-------------VLSGGEQQRLAFARLLLHKPKFVFLDEATSALDEESEDRLYQL--- 133

                        170
                 ....*....|....
gi 256041152 178 LSKNGTTIIFSTHR 191
Cdd:cd03223  134 LKELGITVISVGHR 147
ABC_MTABC3_MDL1_MDL2 cd03249
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ...
 4-209 8.84e-15

ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.


Pssm-ID: 213216 [Multi-domain]  Cd Length: 238  Bit Score: 72.57  E-value: 8.84e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYAT---HKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGiFY-PDKGEILFNG---RPFDPQTDIHAI 76
Cdd:cd03249    1 IEFKNVSFRYPSrpdVPILKGLSLTIPPGKTVALVGSSGCGKSTVVSLLER-FYdPTSGEILLDGvdiRDLNLRWLRSQI 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  77 GYMPEERGLYkKMKVGEQALYLAQLKGMSERDAKDKiKYWFDKFeINSW---YNKKVEE----LSKGMQQKVQFISTIMH 149
Cdd:cd03249   80 GLVSQEPVLF-DGTIAENIRYGKPDATDEEVEEAAK-KANIHDF-IMSLpdgYDTLVGErgsqLSGGQKQRIAIARALLR 156

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 150 SPDLLILDEPFSGLDPINANLIkQEIFDLSKNGTTIIFSTHRMEQVEEiCDRIVLVNQGK 209
Cdd:cd03249  157 NPKILLLDEATSALDAESEKLV-QEALDRAMKGRTTIVIAHRLSTIRN-ADLIAVLQNGQ 214
ABCG_PDR_domain2 cd03232
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ...
 20-211 8.94e-15

Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213199 [Multi-domain]  Cd Length: 192  Bit Score: 71.51  E-value: 8.94e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  20 DDISFAIPKGSIFGLLGPNGAGKTTLL-----RMITGIFypdKGEILFNGRPFDPQTDIhAIGYMPEERGLYKKMKVGEQ 94
Cdd:cd03232   24 NNISGYVKPGTLTALMGESGAGKTTLLdvlagRKTAGVI---TGEILINGRPLDKNFQR-STGYVEQQDVHSPNLTVREA 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  95 ALYLAQLKGMSERDAKdkikywfdKFEINswynkkVEELSKgmqqkvqfistimhsPDLLILDEPFSGLDPINANLIKQE 174
Cdd:cd03232  100 LRFSALLRGLSVEQRK--------RLTIG------VELAAK---------------PSILFLDEPTSGLDSQAAYNIVRF 150

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 256041152 175 IFDLSKNGTTIIFSTHR-MEQVEEICDRIVLVNQGKKL 211
Cdd:cd03232  151 LKKLADSGQAILCTIHQpSASIFEKFDRLLLLKRGGKT 188
PRK10908 PRK10908
cell division ATP-binding protein FtsE;
3-209 9.58e-15

cell division ATP-binding protein FtsE;


Pssm-ID: 182829 [Multi-domain]  Cd Length: 222  Bit Score: 72.21  E-value: 9.58e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   3 LIEIKHLYKHY-ATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGR----------PFDPQT 71
Cdd:PRK10908   1 MIRFEHVSKAYlGGRQALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKIWFSGHditrlknrevPFLRRQ 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  72 dihaIGYMPEERGLYKKMKVGEQALYLAQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSP 151
Cdd:PRK10908  81 ----IGMIFQDHHLLMDRTVYDNVAIPLIIAGASGDDIRRRVSAALDKVGLLDKAKNFPIQLSGGEQQRVGIARAVVNKP 156

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 256041152 152 DLLILDEPFSGLDPINANLIKQEIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGK 209
Cdd:PRK10908 157 AVLLADEPTGNLDDALSEGILRLFEEFNRVGVTVLMATHDIGLISRRSYRMLTLSDGH 214
ABC_FeS_Assembly cd03217
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ...
 4-221 1.14e-14

ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.


Pssm-ID: 213184 [Multi-domain]  Cd Length: 200  Bit Score: 71.40  E-value: 1.14e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGI--FYPDKGEILFNGRpfdpqtDIHAIGymPE 81
Cdd:cd03217    1 LEIKDLHVSVGGKEILKGVNLTIKKGEVHALMGPNGSGKSTLAKTIMGHpkYEVTEGEILFKGE------DITDLP--PE 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  82 ER---GLYkkmkVGEQalYLAQLKGMSerdAKDKIKYWFDKFeinswynkkveelSKGMQQKVQFISTIMHSPDLLILDE 158
Cdd:cd03217   73 ERarlGIF----LAFQ--YPPEIPGVK---NADFLRYVNEGF-------------SGGEKKRNEILQLLLLEPDLAILDE 130

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 256041152 159 PFSGLDPINANLIKQEIFDLSKNGTTIIFSTHRMEQVEEI-CDRIVLVNQGKKLLDGEVKQIKQ 221
Cdd:cd03217  131 PDSGLDIDALRLVAEVINKLREEGKSVLIITHYQRLLDYIkPDRVHVLYDGRIVKSGDKELALE 194
ABCC_TAP cd03248
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ...
 10-209 1.54e-14

ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.


Pssm-ID: 213215 [Multi-domain]  Cd Length: 226  Bit Score: 71.73  E-value: 1.54e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  10 YKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFdPQTD---IHA-IGYMPEERGL 85
Cdd:cd03248   21 YPTRPDTLVLQDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQVLLDGKPI-SQYEhkyLHSkVSLVGQEPVL 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  86 YKKMKVGEQALYLAQLKGMSERDAKDkiKYWFDKF--EINSWYNKKVEE----LSKGMQQKVQFISTIMHSPDLLILDEP 159
Cdd:cd03248  100 FARSLQDNIAYGLQSCSFECVKEAAQ--KAHAHSFisELASGYDTEVGEkgsqLSGGQKQRVAIARALIRNPQVLILDEA 177

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 256041152 160 FSGLDPINANLIKQEIFDLSKNgTTIIFSTHRMEQVEEiCDRIVLVNQGK 209
Cdd:cd03248  178 TSALDAESEQQVQQALYDWPER-RTVLVIAHRLSTVER-ADQILVLDGGR 225
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
22-226 1.62e-14

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 73.79  E-value: 1.62e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  22 ISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPQTDIHAI--GYM--PEER---GLYKKMKVGEQ 94
Cdd:PRK11288 272 ISFSVRAGEIVGLFGLVGAGRSELMKLLYGATRRTAGQVYLDGKPIDIRSPRDAIraGIMlcPEDRkaeGIIPVHSVADN 351

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  95 AlylaqlkGMSERDAKDKIKYWFDkfeiNSWYNKKVEE------------------LSKGMQQKV---QFISTIMhspDL 153
Cdd:PRK11288 352 I-------NISARRHHLRAGCLIN----NRWEAENADRfirslniktpsreqlimnLSGGNQQKAilgRWLSEDM---KV 417

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 256041152 154 LILDEPFSGLDPINANLIKQEIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGKklLDGEVKqiKQDFKQH 226
Cdd:PRK11288 418 ILLDEPTRGIDVGAKHEIYNVIYELAAQGVAVLFVSSDLPEVLGVADRIVVMREGR--IAGELA--REQATER 486
DUF4162 pfam13732
Domain of unknown function (DUF4162); This domain is found at the C-terminus of bacterial ABC ...
 214-298 2.22e-14

Domain of unknown function (DUF4162); This domain is found at the C-terminus of bacterial ABC transporter proteins. The function is not known.


Pssm-ID: 463971 [Multi-domain]  Cd Length: 82  Bit Score: 67.23  E-value: 2.22e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  214 GEVKQIKQDFKQHLFRIGFGVMPNFAQVAthHFSIIKQEPLAYTVKLTEGSTNNDILAhFIRHNVPITSFQEILPSINEV 293
Cdd:pfam13732   1 GTLEEIKRSYGRNRIEVETADAEELLELP--GVEEVEEEGGGLELKLEDEEAANELLA-ALLSGGEIRSFEEEEPSLNDI 77


                  ....*
gi 256041152  294 FIQQV 298
Cdd:pfam13732  78 FIEKV 82
3a01208 TIGR00958
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
 3-227 3.30e-14

Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273363 [Multi-domain]  Cd Length: 711  Bit Score: 73.22  E-value: 3.30e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152    3 LIEIKHLYKHYATHKAV---DDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFdPQTDIH----A 75
Cdd:TIGR00958 478 LIEFQDVSFSYPNRPDVpvlKGLTFTLHPGEVVALVGPSGSGKSTVAALLQNLYQPTGGQVLLDGVPL-VQYDHHylhrQ 556

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   76 IGYMPEERGLYKKmKVGEQALYLAQLKGMSERDAKDKIKYWFDKF-EINSWYNKKVEE----LSKGMQQKVQFISTIMHS 150
Cdd:TIGR00958 557 VALVGQEPVLFSG-SVRENIAYGLTDTPDEEIMAAAKAANAHDFImEFPNGYDTEVGEkgsqLSGGQKQRIAIARALVRK 635

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 256041152  151 PDLLILDEPFSGLDPINANLIKQeifDLSKNGTTIIFSTHRMEQVEEiCDRIVLVNQGKKLLDGEVKQI--KQDFKQHL 227
Cdd:TIGR00958 636 PRVLILDEATSALDAECEQLLQE---SRSRASRTVLLIAHRLSTVER-ADQILVLKKGSVVEMGTHKQLmeDQGCYKHL 710
PRK14271 PRK14271
phosphate ABC transporter ATP-binding protein; Provisional
 13-219 3.34e-14

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172759 [Multi-domain]  Cd Length: 276  Bit Score: 71.67  E-value: 3.34e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  13 YATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIF-----YPDKGEILFNGRPFDPQTDI----HAIGYM---- 79
Cdd:PRK14271  31 FAGKTVLDQVSMGFPARAVTSLMGPTGSGKTTFLRTLNRMNdkvsgYRYSGDVLLGGRSIFNYRDVlefrRRVGMLfqrp 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  80 -PEERGLYKKMKVGEQALYLA---QLKGMSERDAKDkIKYWFdkfEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLI 155
Cdd:PRK14271 111 nPFPMSIMDNVLAGVRAHKLVprkEFRGVAQARLTE-VGLWD---AVKDRLSDSPFRLSGGQQQLLCLARTLAVNPEVLL 186

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 256041152 156 LDEPFSGLDPINANLIKQEIFDLSkNGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQI 219
Cdd:PRK14271 187 LDEPTSALDPTTTEKIEEFIRSLA-DRLTVIIVTHNLAQAARISDRAALFFDGRLVEEGPTEQL 249
modC PRK11144
molybdenum ABC transporter ATP-binding protein ModC;
21-209 3.41e-14

molybdenum ABC transporter ATP-binding protein ModC;


Pssm-ID: 182993 [Multi-domain]  Cd Length: 352  Bit Score: 72.21  E-value: 3.41e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  21 DISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRP-FDPQTDIH------AIGYMPEERGLYKKMKVGE 93
Cdd:PRK11144  16 TVNLTLPAQGITAIFGRSGAGKTSLINAISGLTRPQKGRIVLNGRVlFDAEKGIClppekrRIGYVFQDARLFPHYKVRG 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  94 QALYlaqlkGMSERDAK--DK------IKYWFDKFEINswynkkveeLSKGMQQKVQFISTIMHSPDLLILDEPFSGLD- 164
Cdd:PRK11144  96 NLRY-----GMAKSMVAqfDKivallgIEPLLDRYPGS---------LSGGEKQRVAIGRALLTAPELLLMDEPLASLDl 161

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 256041152 165 PinanlIKQEIFD----LSKN-GTTIIFSTHRMEQVEEICDRIVLVNQGK 209
Cdd:PRK11144 162 P-----RKRELLPylerLAREiNIPILYVSHSLDEILRLADRVVVLEQGK 206
ABC_RNaseL_inhibitor_domain2 cd03237
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
 26-164 5.40e-14

The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213204 [Multi-domain]  Cd Length: 246  Bit Score: 70.51  E-value: 5.40e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  26 IPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILfngrpfdpqTDIHAIGYMPEERGLYKKMKVgeQALYLAQLKGMS 105
Cdd:cd03237   22 ISESEVIGILGPNGIGKTTFIKMLAGVLKPDEGDIE---------IELDTVSYKPQYIKADYEGTV--RDLLSSITKDFY 90

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 256041152 106 ERdakdkiKYW----FDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEPFSGLD 164
Cdd:cd03237   91 TH------PYFkteiAKPLQIEQILDREVPELSGGELQRVAIAACLSKDADIYLLDEPSAYLD 147
YddA COG4178
ABC-type uncharacterized transport system, permease and ATPase components [General function ...
 19-191 2.00e-13

ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];


Pssm-ID: 443337 [Multi-domain]  Cd Length: 571  Bit Score: 70.61  E-value: 2.00e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  19 VDDISFAIPKGSifGLL--GPNGAGKTTLLRMITG--------IFYPDKGEILF-NGRPFDPQ-TDIHAIGYmPEERGLY 86
Cdd:COG4178  379 LEDLSLSLKPGE--RLLitGPSGSGKSTLLRAIAGlwpygsgrIARPAGARVLFlPQRPYLPLgTLREALLY-PATAEAF 455

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  87 KKMKVgEQALYLAQLKGMSERdakdkikywFDkfEINSWYNkkveELSKGMQQKVQFISTIMHSPDLLILDEPFSGLDPI 166
Cdd:COG4178  456 SDAEL-REALEAVGLGHLAER---------LD--EEADWDQ----VLSLGEQQRLAFARLLLHKPDWLFLDEATSALDEE 519

                        170       180
                 ....*....|....*....|....*....
gi 256041152 167 NAN----LIKQEIFDlskngTTIIFSTHR 191
Cdd:COG4178  520 NEAalyqLLREELPG-----TTVISVGHR 543
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
 3-219 2.22e-13

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 70.48  E-value: 2.22e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   3 LIEIKHLYKHYAT-----------HKAVDDISFAIPKGSIFGLLGPNGAGKTTL----LRMItgifyPDKGEILFNGRPF 67
Cdd:COG4172  275 LLEARDLKVWFPIkrglfrrtvghVKAVDGVSLTLRRGETLGLVGESGSGKSTLglalLRLI-----PSEGEIRFDGQDL 349

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  68 DpqtdihaiGYMPEE-RGLYKK---------------MKVGE---QALYLAQLkGMSERDAKDKIKYWFDKFEIN-SWYN 127
Cdd:COG4172  350 D--------GLSRRAlRPLRRRmqvvfqdpfgslsprMTVGQiiaEGLRVHGP-GLSAAERRARVAEALEEVGLDpAARH 420

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 128 KKVEELSKGMQQKvqfIST----IMHsPDLLILDEPFSGLDpinaNLIKQEIFDL-----SKNGTTIIFSTHRMEQVEEI 198
Cdd:COG4172  421 RYPHEFSGGQRQR---IAIaralILE-PKLLVLDEPTSALD----VSVQAQILDLlrdlqREHGLAYLFISHDLAVVRAL 492

                        250       260
                 ....*....|....*....|.
gi 256041152 199 CDRIVLVNQGKKLLDGEVKQI 219
Cdd:COG4172  493 AHRVMVMKDGKVVEQGPTEQV 513
PRK14258 PRK14258
phosphate ABC transporter ATP-binding protein; Provisional
 4-200 2.27e-13

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184593 [Multi-domain]  Cd Length: 261  Bit Score: 68.91  E-value: 2.27e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIfYPDKGEI-------LFNGRPFDPQTDIH-- 74
Cdd:PRK14258   8 IKVNNLSFYYDTQKILEGVSMEIYQSKVTAIIGPSGCGKSTFLKCLNRM-NELESEVrvegrveFFNQNIYERRVNLNrl 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  75 --AIGYMPEERGLYKkMKVGEQALYLAQLKGMSERDAKDKI--------KYWFdkfEINSWYNKKVEELSKGMQQKVQFI 144
Cdd:PRK14258  87 rrQVSMVHPKPNLFP-MSVYDNVAYGVKIVGWRPKLEIDDIvesalkdaDLWD---EIKHKIHKSALDLSGGQQQRLCIA 162

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 256041152 145 STIMHSPDLLILDEPFSGLDPINANLIKQEIFDLS-KNGTTIIFSTHRMEQVEEICD 200
Cdd:PRK14258 163 RALAVKPKVLLMDEPCFGLDPIASMKVESLIQSLRlRSELTMVIVSHNLHQVSRLSD 219
PRK10584 PRK10584
putative ABC transporter ATP-binding protein YbbA; Provisional
 2-209 3.23e-13

putative ABC transporter ATP-binding protein YbbA; Provisional


Pssm-ID: 182569 [Multi-domain]  Cd Length: 228  Bit Score: 67.88  E-value: 3.23e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   2 NLIEIKHLYKHYATHKAVDDI----SFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPfdpqtdIHAig 77
Cdd:PRK10584   5 NIVEVHHLKKSVGQGEHELSIltgvELVVKRGETIALIGESGSGKSTLLAILAGLDDGSSGEVSLVGQP------LHQ-- 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  78 yMPEE-RGLYKKMKVG---------------EQALYLAQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKV 141
Cdd:PRK10584  77 -MDEEaRAKLRAKHVGfvfqsfmliptlnalENVELPALLRGESSRQSRNGAKALLEQLGLGKRLDHLPAQLSGGEQQRV 155

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 256041152 142 QFISTIMHSPDLLILDEPFSGLDPINANLIKQEIFDLSKN-GTTIIFSTHRmEQVEEICDRIVLVNQGK 209
Cdd:PRK10584 156 ALARAFNGRPDVLFADEPTGNLDRQTGDKIADLLFSLNREhGTTLILVTHD-LQLAARCDRRLRLVNGQ 223
PRK13538 PRK13538
cytochrome c biogenesis heme-transporting ATPase CcmA;
20-190 3.93e-13

cytochrome c biogenesis heme-transporting ATPase CcmA;


Pssm-ID: 184125 [Multi-domain]  Cd Length: 204  Bit Score: 67.14  E-value: 3.93e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  20 DDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPQTDIHA-----IGYMPeerGLYKKMKVGEQ 94
Cdd:PRK13538  18 SGLSFTLNAGELVQIEGPNGAGKTSLLRILAGLARPDAGEVLWQGEPIRRQRDEYHqdllyLGHQP---GIKTELTALEN 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  95 ALYLAQLKGMSERDAkdkikYW-------FDKFEinswyNKKVEELSKGMQQKVQFISTIMHSPDLLILDEPFSGLDPIN 167
Cdd:PRK13538  95 LRFYQRLHGPGDDEA-----LWealaqvgLAGFE-----DVPVRQLSAGQQRRVALARLWLTRAPLWILDEPFTAIDKQG 164

                        170       180
                 ....*....|....*....|...
gi 256041152 168 ANLIKQEIFDLSKNGTTIIFSTH 190
Cdd:PRK13538 165 VARLEALLAQHAEQGGMVILTTH 187
cbiO PRK13645
energy-coupling factor transporter ATPase;
17-219 6.64e-13

energy-coupling factor transporter ATPase;


Pssm-ID: 184204 [Multi-domain]  Cd Length: 289  Bit Score: 67.73  E-value: 6.64e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  17 KAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPF-----------DPQTDIHAIGYMPEERgL 85
Cdd:PRK13645  25 KALNNTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGLIISETGQTIVGDYAIpanlkkikevkRLRKEIGLVFQFPEYQ-L 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  86 YKKMKVGEQALYLAQLkGMSERDAKDKIKYWFDKFEINSWYNKKVE-ELSKGMQQKVQFISTIMHSPDLLILDEPFSGLD 164
Cdd:PRK13645 104 FQETIEKDIAFGPVNL-GENKQEAYKKVPELLKLVQLPEDYVKRSPfELSGGQKRRVALAGIIAMDGNTLVLDEPTGGLD 182

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 256041152 165 PINANLIKQEIFDLSKN-GTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQI 219
Cdd:PRK13645 183 PKGEEDFINLFERLNKEyKKRIIMVTHNMDQVLRIADEVIVMHEGKVISIGSPFEI 238
PRK10938 PRK10938
putative molybdenum transport ATP-binding protein ModF; Provisional
 2-208 7.88e-13

putative molybdenum transport ATP-binding protein ModF; Provisional


Pssm-ID: 182852 [Multi-domain]  Cd Length: 490  Bit Score: 68.89  E-value: 7.88e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   2 NLIEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGifypDKGE------ILFNGRPFDPQT--DI 73
Cdd:PRK10938 259 PRIVLNNGVVSYNDRPILHNLSWQVNPGEHWQIVGPNGAGKSTLLSLITG----DHPQgysndlTLFGRRRGSGETiwDI 334

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  74 --HaIGYMP-----EER-----------------GLYKKMKVGEQAL---YLAQLkGMSERDAkdkikywfdkfeinswy 126
Cdd:PRK10938 335 kkH-IGYVSsslhlDYRvstsvrnvilsgffdsiGIYQAVSDRQQKLaqqWLDIL-GIDKRTA----------------- 395

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 127 NKKVEELSKGmQQKVQFISTIM--HsPDLLILDEPFSGLDPINANLIKQEIFDLSKNG-TTIIFSTHRMEQVEE-ICDRI 202
Cdd:PRK10938 396 DAPFHSLSWG-QQRLALIVRALvkH-PTLLILDEPLQGLDPLNRQLVRRFVDVLISEGeTQLLFVSHHAEDAPAcITHRL 473


                 ....*.
gi 256041152 203 VLVNQG 208
Cdd:PRK10938 474 EFVPDG 479
lolD PRK11629
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
21-190 9.35e-13

lipoprotein-releasing ABC transporter ATP-binding protein LolD;


Pssm-ID: 183244 [Multi-domain]  Cd Length: 233  Bit Score: 66.76  E-value: 9.35e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  21 DISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPQTDI-------HAIGYMPEERGLYKKMKVGE 93
Cdd:PRK11629  27 NVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNGQPMSKLSSAakaelrnQKLGFIYQFHHLLPDFTALE 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  94 QALYLAQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEPFSGLDPINANLIKQ 173
Cdd:PRK11629 107 NVAMPLLIGKKKPAEINSRALEMLAAVGLEHRANHRPSELSGGERQRVAIARALVNNPRLVLADEPTGNLDARNADSIFQ 186

                        170
                 ....*....|....*...
gi 256041152 174 EIFDLS-KNGTTIIFSTH 190
Cdd:PRK11629 187 LLGELNrLQGTAFLVVTH 204
PRK11174 PRK11174
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
 22-229 1.04e-12

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236870 [Multi-domain]  Cd Length: 588  Bit Score: 68.33  E-value: 1.04e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  22 ISFAIPKGSIFGLLGPNGAGKTTLLRMITGiFYPDKGEILFNG---RPFDPQTDIHAIGYMPEERGLYKkmkvG--EQAL 96
Cdd:PRK11174 369 LNFTLPAGQRIALVGPSGAGKTSLLNALLG-FLPYQGSLKINGielRELDPESWRKHLSWVGQNPQLPH----GtlRDNV 443

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  97 YLAQlKGMSERDAKDKIKywfdkfeiNSWYNKKVEELSKGMQ---------------QKVQFISTIMHSPDLLILDEPFS 161
Cdd:PRK11174 444 LLGN-PDASDEQLQQALE--------NAWVSEFLPLLPQGLDtpigdqaaglsvgqaQRLALARALLQPCQLLLLDEPTA 514

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 256041152 162 GLDPINANLIKQEIFDLSKNGTTIIFsTHRMEQVEEiCDRIVLVNQGKKLLDGEVKQIKQDfkQHLFR 229
Cdd:PRK11174 515 SLDAHSEQLVMQALNAASRRQTTLMV-THQLEDLAQ-WDQIWVMQDGQIVQQGDYAELSQA--GGLFA 578
SapD COG4170
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];
1-244 1.25e-12

ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];


Pssm-ID: 443330 [Multi-domain]  Cd Length: 331  Bit Score: 67.62  E-value: 1.25e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   1 MNLIEIKHLYKHYATH----KAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFyPDKGEILFNGRPFDpqtDIHAI 76
Cdd:COG4170    1 MPLLDIRNLTIEIDTPqgrvKAVDRVSLTLNEGEIRGLVGESGSGKSLIAKAICGIT-KDNWHVTADRFRWN---GIDLL 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  77 GYMPEER-----------------GLYKKMKVGEQ---ALYLAQLKGMSERDAKDKIKY---WFDKFEINswYNKKV--- 130
Cdd:COG4170   77 KLSPRERrkiigreiamifqepssCLDPSAKIGDQlieAIPSWTFKGKWWQRFKWRKKRaieLLHRVGIK--DHKDImns 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 131 --EELSKGMQQKVQFISTIMHSPDLLILDEPFSGLDPINanliKQEIFDL-SK----NGTTIIFSTHRMEQVEEICDRIV 203
Cdd:COG4170  155 ypHELTEGECQKVMIAMAIANQPRLLIADEPTNAMESTT----QAQIFRLlARlnqlQGTSILLISHDLESISQWADTIT 230

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*
gi 256041152 204 LVNQGKKLLDGEVKQIKQD----FKQHLFRigfgVMPNFAQVATH 244
Cdd:COG4170  231 VLYCGQTVESGPTEQILKSphhpYTKALLR----SMPDFRQPLPH 271
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
26-164 1.54e-12

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 67.91  E-value: 1.54e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  26 IPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRpfdpqtdihaIGYMPEERGLYKKMKVGEqalYLaqlkgms 105
Cdd:PRK13409 362 IYEGEVIGIVGPNGIGKTTFAKLLAGVLKPDEGEVDPELK----------ISYKPQYIKPDYDGTVED---LL------- 421

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 256041152 106 eRDAKDKI--KYW----FDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEPFSGLD 164
Cdd:PRK13409 422 -RSITDDLgsSYYkseiIKPLQLERLLDKNVKDLSGGELQRVAIAACLSRDADLYLLDEPSAHLD 485
PRK15064 PRK15064
ABC transporter ATP-binding protein; Provisional
 2-203 2.20e-12

ABC transporter ATP-binding protein; Provisional


Pssm-ID: 237894 [Multi-domain]  Cd Length: 530  Bit Score: 67.61  E-value: 2.20e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   2 NLIEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFngrpfdpqTDIHAIGYMPE 81
Cdd:PRK15064 318 NALEVENLTKGFDNGPLFKNLNLLLEAGERLAIIGENGVGKTTLLRTLVGELEPDSGTVKW--------SENANIGYYAQ 389

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  82 ER--------------GLYKKMKVGEQAlylaqLKGMSERdakdkikYWFDKFEInswyNKKVEELSKGMQQKVQFISTI 147
Cdd:PRK15064 390 DHaydfendltlfdwmSQWRQEGDDEQA-----VRGTLGR-------LLFSQDDI----KKSVKVLSGGEKGRMLFGKLM 453

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 256041152 148 MHSPDLLILDEPFSGLD--PINANLIKQEIFDlskngTTIIFSTHRMEQVEEICDRIV 203
Cdd:PRK15064 454 MQKPNVLVMDEPTNHMDmeSIESLNMALEKYE-----GTLIFVSHDREFVSSLATRII 506
PRK13543 PRK13543
heme ABC exporter ATP-binding protein CcmA;
22-190 3.37e-12

heme ABC exporter ATP-binding protein CcmA;


Pssm-ID: 184129 [Multi-domain]  Cd Length: 214  Bit Score: 64.87  E-value: 3.37e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  22 ISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPQTDIHAIGYMPEERGLYKKMKVGEQALYLAQL 101
Cdd:PRK13543  30 LDFHVDAGEALLVQGDNGAGKTTLLRVLAGLLHVESGQIQIDGKTATRGDRSRFMAYLGHLPGLKADLSTLENLHFLCGL 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 102 KGmseRDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEPFSGLDPINANLIKQEIFDLSKN 181
Cdd:PRK13543 110 HG---RRAKQMPGSALAIVGLAGYEDTLVRQLSAGQKKRLALARLWLSPAPLWLLDEPYANLDLEGITLVNRMISAHLRG 186


                 ....*....
gi 256041152 182 GTTIIFSTH 190
Cdd:PRK13543 187 GGAALVTTH 195
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
 16-230 3.62e-12

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 66.65  E-value: 3.62e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  16 HKAVDDISFAIPKGSIFGLLGPNGAGKTT----LLRMItgifyPDKGEILFNGRP------------------------- 66
Cdd:PRK15134 299 NVVVKNISFTLRPGETLGLVGESGSGKSTtglaLLRLI-----NSQGEIWFDGQPlhnlnrrqllpvrhriqvvfqdpns 373

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  67 -FDPQTDIHAIgympEERGLykkmKVGEQALYLAQ-----LKGMSE--RDAKDKIKYwfdkfeinswynkkVEELSKGMQ 138
Cdd:PRK15134 374 sLNPRLNVLQI----IEEGL----RVHQPTLSAAQreqqvIAVMEEvgLDPETRHRY--------------PAEFSGGQR 431

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 139 QKVQFISTIMHSPDLLILDEPFSGLDpinaNLIKQEIFDL-----SKNGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLD 213
Cdd:PRK15134 432 QRIAIARALILKPSLIILDEPTSSLD----KTVQAQILALlkslqQKHQLAYLFISHDLHVVRALCHQVIVLRQGEVVEQ 507

                        250       260
                 ....*....|....*....|.
gi 256041152 214 GEVKQI----KQDFKQHLFRI 230
Cdd:PRK15134 508 GDCERVfaapQQEYTRQLLAL 528
ABCC_CFTR1 cd03291
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ...
 21-239 5.61e-12

ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.


Pssm-ID: 213258 [Multi-domain]  Cd Length: 282  Bit Score: 65.26  E-value: 5.61e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  21 DISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGR-PFDPQTDIHAIGYMPEE--RGL----YKKMKVGE 93
Cdd:cd03291   55 NINLKIEKGEMLAITGSTGSGKTSLLMLILGELEPSEGKIKHSGRiSFSSQFSWIMPGTIKENiiFGVsydeYRYKSVVK 134

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  94 QALYLAQLKGMSERDakdkikywfdkfeiNSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEPFSGLDPinanLIKQ 173
Cdd:cd03291  135 ACQLEEDITKFPEKD--------------NTVLGEGGITLSGGQRARISLARAVYKDADLYLLDSPFGYLDV----FTEK 196

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 256041152 174 EIFD-----LSKNGTTIIFsTHRMEQVeEICDRIVLVNQGKKLLDG---EVKQIKQDFKQHLfrIGFGVMPNFA 239
Cdd:cd03291  197 EIFEscvckLMANKTRILV-TSKMEHL-KKADKILILHEGSSYFYGtfsELQSLRPDFSSKL--MGYDTFDQFS 266
cbiO PRK13646
energy-coupling factor transporter ATPase;
16-208 5.79e-12

energy-coupling factor transporter ATPase;


Pssm-ID: 184205 [Multi-domain]  Cd Length: 286  Bit Score: 65.19  E-value: 5.79e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  16 HKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPQTDIHAIGYMPEERGLYKKM------ 89
Cdd:PRK13646  20 HQAIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDITITHKTKDKYIRPVRKRIGMVFQFpesqlf 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  90 --KVGEQALYLAQLKGMSERDAKDK-----IKYWFDKfEINSwynKKVEELSKGMQQKVQFISTIMHSPDLLILDEPFSG 162
Cdd:PRK13646 100 edTVEREIIFGPKNFKMNLDEVKNYahrllMDLGFSR-DVMS---QSPFQMSGGQMRKIAIVSILAMNPDIIVLDEPTAG 175

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 256041152 163 LDPINanliKQEIFDLSK-----NGTTIIFSTHRMEQVEEICDRIVLVNQG 208
Cdd:PRK13646 176 LDPQS----KRQVMRLLKslqtdENKTIILVSHDMNEVARYADEVIVMKEG 222
HisP COG4598
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];
4-209 7.00e-12

ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443652 [Multi-domain]  Cd Length: 259  Bit Score: 64.44  E-value: 7.00e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPQTDIHAiGYMPEER 83
Cdd:COG4598    9 LEVRDLHKSFGDLEVLKGVSLTARKGDVISIIGSSGSGKSTFLRCINLLETPDSGEIRVGGEEIRLKPDRDG-ELVPADR 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  84 -----------------GLYKKMKVGEQaLYLA--QLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFI 144
Cdd:COG4598   88 rqlqrirtrlgmvfqsfNLWSHMTVLEN-VIEApvHVLGRPKAEAIERAEALLAKVGLADKRDAYPAHLSGGQQQRAAIA 166

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 256041152 145 STIMHSPDLLILDEPFSGLDPinaNLIkQE----IFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGK 209
Cdd:COG4598  167 RALAMEPEVMLFDEPTSALDP---ELV-GEvlkvMRDLAEEGRTMLVVTHEMGFARDVSSHVVFLHQGR 231
PRK13541 PRK13541
cytochrome c biogenesis protein CcmA; Provisional
 21-190 1.33e-11

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 184128 [Multi-domain]  Cd Length: 195  Bit Score: 62.58  E-value: 1.33e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  21 DISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNG-------RPFdpqtdihaIGYMPEERGLYKKMKVGE 93
Cdd:PRK13541  18 DLSITFLPSAITYIKGANGCGKSSLLRMIAGIMQPSSGNIYYKNcninniaKPY--------CTYIGHNLGLKLEMTVFE 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  94 QALYLAQLKGMSERdAKDKIKYwfdkFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEPFSGLDPINANLIKQ 173
Cdd:PRK13541  90 NLKFWSEIYNSAET-LYAAIHY----FKLHDLLDEKCYSLSSGMQKIVAIARLIACQSDLWLLDEVETNLSKENRDLLNN 164

                        170
                 ....*....|....*..
gi 256041152 174 EIFDLSKNGTTIIFSTH 190
Cdd:PRK13541 165 LIVMKANSGGIVLLSSH 181
dppD PRK11022
dipeptide transporter ATP-binding subunit; Provisional
 1-240 2.14e-11

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 182906 [Multi-domain]  Cd Length: 326  Bit Score: 63.61  E-value: 2.14e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   1 MNLIEIKHLYKHY----ATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITG-IFYPDK---GEILFNGRPF----- 67
Cdd:PRK11022   1 MALLNVDKLSVHFgdesAPFRAVDRISYSVKQGEVVGIVGESGSGKSVSSLAIMGlIDYPGRvmaEKLEFNGQDLqrise 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  68 ----------------DPQTDI---HAIGYMPEE-----RGLYKKMKVgEQALYLAQLKGMSERDAKdkikywFDKFEin 123
Cdd:PRK11022  81 kerrnlvgaevamifqDPMTSLnpcYTVGFQIMEaikvhQGGNKKTRR-QRAIDLLNQVGIPDPASR------LDVYP-- 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 124 swynkkvEELSKGMQQKVQFISTIMHSPDLLILDEPFSGLD-PINANLIKQEIFDLSKNGTTIIFSTHRMEQVEEICDRI 202
Cdd:PRK11022 152 -------HQLSGGMSQRVMIAMAIACRPKLLIADEPTTALDvTIQAQIIELLLELQQKENMALVLITHDLALVAEAAHKI 224

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|..
gi 256041152 203 VLVNQGKKLLDGEVKQI----KQDFKQHLFRigfgVMPNFAQ 240
Cdd:PRK11022 225 IVMYAGQVVETGKAHDIfrapRHPYTQALLR----ALPEFAQ 262
ABCC_NFT1 cd03369
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ...
 4-209 2.34e-11

ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213269 [Multi-domain]  Cd Length: 207  Bit Score: 62.04  E-value: 2.34e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYATH--KAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRpfdpqtDIHAIGYmpe 81
Cdd:cd03369    7 IEVENLSVRYAPDlpPVLKNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAEEGKIEIDGI------DISTIPL--- 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  82 eRGLYKKMKVGEQ--ALYLAQLKgmSERDAKDKikywFDKFEInsWYNKKVEE----LSKGMQQKVQFISTIMHSPDLLI 155
Cdd:cd03369   78 -EDLRSSLTIIPQdpTLFSGTIR--SNLDPFDE----YSDEEI--YGALRVSEgglnLSQGQRQLLCLARALLKRPRVLV 148

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 256041152 156 LDEPFSGLDPINANLIkQEIFDLSKNGTTIIFSTHRMEQVEEiCDRIVLVNQGK 209
Cdd:cd03369  149 LDEATASIDYATDALI-QKTIREEFTNSTILTIAHRLRTIID-YDKILVMDAGE 200
dppF PRK11308
dipeptide transporter ATP-binding subunit; Provisional
 3-219 3.04e-11

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 236898 [Multi-domain]  Cd Length: 327  Bit Score: 63.45  E-value: 3.04e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   3 LIEIKHLYKHY----------ATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGrpfdpqtd 72
Cdd:PRK11308   5 LLQAIDLKKHYpvkrglfkpeRLVKALDGVSFTLERGKTLAVVGESGCGKSTLARLLTMIETPTGGELYYQG-------- 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  73 IHAIGYMPEERGLYKKM----------------KVG---EQALYLAQLKGMSERdaKDKIKYWFDKFEINS-WYNKKVEE 132
Cdd:PRK11308  77 QDLLKADPEAQKLLRQKiqivfqnpygslnprkKVGqilEEPLLINTSLSAAER--REKALAMMAKVGLRPeHYDRYPHM 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 133 LSKGMQQKVQFISTIMHSPDLLILDEPFSGLD-PINA---NLikqeIFDLSKN-GTTIIFSTHRMEQVEEICDRIVLVNQ 207
Cdd:PRK11308 155 FSGGQRQRIAIARALMLDPDVVVADEPVSALDvSVQAqvlNL----MMDLQQElGLSYVFISHDLSVVEHIADEVMVMYL 230

                        250
                 ....*....|..
gi 256041152 208 GKKLLDGEVKQI 219
Cdd:PRK11308 231 GRCVEKGTKEQI 242
PRK10522 PRK10522
multidrug transporter membrane component/ATP-binding component; Provisional
 4-218 4.46e-11

multidrug transporter membrane component/ATP-binding component; Provisional


Pssm-ID: 236707 [Multi-domain]  Cd Length: 547  Bit Score: 63.45  E-value: 4.46e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYATHK-AVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPQ------------ 70
Cdd:PRK10522 323 LELRNVTFAYQDNGfSVGPINLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEILLDGKPVTAEqpedyrklfsav 402

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  71 -TDIHAIGYMPEERGLYKKMKVGEQalYLAQLKgMserdaKDKIkywfdKFEINSWYNKKveeLSKGMQQKVQFISTIMH 149
Cdd:PRK10522 403 fTDFHLFDQLLGPEGKPANPALVEK--WLERLK-M-----AHKL-----ELEDGRISNLK---LSKGQKKRLALLLALAE 466

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 256041152 150 SPDLLILDEPFSGLDPINANLIKQEIFDLSKN-GTTIIFSTHRmEQVEEICDRIVLVNQGK-KLLDGEVKQ 218
Cdd:PRK10522 467 ERDILLLDEWAADQDPHFRREFYQVLLPLLQEmGKTIFAISHD-DHYFIHADRLLEMRNGQlSELTGEERD 536
3a01205 TIGR00956
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
 29-210 5.37e-11

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273362 [Multi-domain]  Cd Length: 1394  Bit Score: 63.59  E-value: 5.37e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152    29 GSIFGLLGPNGAGKTTLL-----RMITGIFypDKGEILFNGRPFDpQTDIHAIGYMpEERGLYKKMKVGEQAL----YLA 99
Cdd:TIGR00956  789 GTLTALMGASGAGKTTLLnvlaeRVTTGVI--TGGDRLVNGRPLD-SSFQRSIGYV-QQQDLHLPTSTVRESLrfsaYLR 864

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   100 QLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGM---QQKVQFIST-IMHSPDLLI-LDEPFSGLDPINANLIKQE 174
Cdd:TIGR00956  865 QPKSVSKSEKMEYVEEVIKLLEMESYADAVVGVPGEGLnveQRKRLTIGVeLVAKPKLLLfLDEPTSGLDSQTAWSICKL 944

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|.
gi 256041152   175 IFDLSKNGTTIIFSTHR-----MEQVeeicDRIVLVNQGKK 210
Cdd:TIGR00956  945 MRKLADHGQAILCTIHQpsailFEEF----DRLLLLQKGGQ 981
cbiO PRK13642
energy-coupling factor transporter ATPase;
3-209 7.74e-11

energy-coupling factor transporter ATPase;


Pssm-ID: 184202 [Multi-domain]  Cd Length: 277  Bit Score: 61.65  E-value: 7.74e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   3 LIEIKHLYKHYATHKAVDD---ISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPQT------DI 73
Cdd:PRK13642   4 ILEVENLVFKYEKESDVNQlngVSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGKVKIDGELLTAENvwnlrrKI 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  74 HAIGYMPEERglYKKMKVGEQALYLAQLKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDL 153
Cdd:PRK13642  84 GMVFQNPDNQ--FVGATVEDDVAFGMENQGIPREEMIKRVDEALLAVNMLDFKTREPARLSGGQKQRVAVAGIIALRPEI 161

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 256041152 154 LILDEPFSGLDPINANLIKQEIFDLS-KNGTTIIFSTHRMEQVEEiCDRIVLVNQGK 209
Cdd:PRK13642 162 IILDESTSMLDPTGRQEIMRVIHEIKeKYQLTVLSITHDLDEAAS-SDRILVMKAGE 217
PRK10789 PRK10789
SmdA family multidrug ABC transporter permease/ATP-binding protein;
4-221 8.79e-11

SmdA family multidrug ABC transporter permease/ATP-binding protein;


Pssm-ID: 182732 [Multi-domain]  Cd Length: 569  Bit Score: 62.81  E-value: 8.79e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFdPQTDIHA-------I 76
Cdd:PRK10789 316 VNIRQFTYPQTDHPALENVNFTLKPGQMLGICGPTGSGKSTLLSLIQRHFDVSEGDIRFHDIPL-TKLQLDSwrsrlavV 394

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  77 GYMP--------EERGLYKKMKVGEQALYLAQLKGMSErdakdkikywfDKFEINSWYNKKVEE----LSKGMQQKVQFI 144
Cdd:PRK10789 395 SQTPflfsdtvaNNIALGRPDATQQEIEHVARLASVHD-----------DILRLPQGYDTEVGErgvmLSGGQKQRISIA 463

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 256041152 145 STIMHSPDLLILDEPFSGLDPINANLIKQEIFDLSKnGTTIIFSTHRMEQVEEiCDRIVLVNQGKKLLDGEVKQIKQ 221
Cdd:PRK10789 464 RALLLNAEILILDDALSAVDGRTEHQILHNLRQWGE-GRTVIISAHRLSALTE-ASEILVMQHGHIAQRGNHDQLAQ 538
ABCC_CFTR2 cd03289
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ...
 4-209 1.11e-10

ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.


Pssm-ID: 213256 [Multi-domain]  Cd Length: 275  Bit Score: 61.02  E-value: 1.11e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHY--ATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDkGEILFNGRPFDP---QTDIHAIGY 78
Cdd:cd03289    3 MTVKDLTAKYteGGNAVLENISFSISPGQRVGLLGRTGSGKSTLLSAFLRLLNTE-GDIQIDGVSWNSvplQKWRKAFGV 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  79 MPEE----RGLYKKM-----KVGEQALYlaqlKGMSERDAKDKIKYWFDKFEINSWYNKKVeeLSKGMQQKVQFISTIMH 149
Cdd:cd03289   82 IPQKvfifSGTFRKNldpygKWSDEEIW----KVAEEVGLKSVIEQFPGQLDFVLVDGGCV--LSHGHKQLMCLARSVLS 155

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 150 SPDLLILDEPFSGLDPINANLIKQeIFDLSKNGTTIIFSTHRMEQVEEiCDRIVLVNQGK 209
Cdd:cd03289  156 KAKILLLDEPSAHLDPITYQVIRK-TLKQAFADCTVILSEHRIEAMLE-CQRFLVIEENK 213
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
 26-186 2.58e-10

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 61.34  E-value: 2.58e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  26 IPK-GSIFGLLGPNGAGKTTLLRMITGIFYP---------DKGEIL--FNGrpfdpqTDIHAigYMpeeRGLY-KKMKVG 92
Cdd:COG1245   95 VPKkGKVTGILGPNGIGKSTALKILSGELKPnlgdydeepSWDEVLkrFRG------TELQD--YF---KKLAnGEIKVA 163

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  93 EQALYLAQ------------LKGMSERDAKDKIKywfDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEPF 160
Cdd:COG1245  164 HKPQYVDLipkvfkgtvrelLEKVDERGKLDELA---EKLGLENILDRDISELSGGELQRVAIAAALLRDADFYFFDEPS 240

                        170       180       190
                 ....*....|....*....|....*....|
gi 256041152 161 SGLD---PIN-ANLIKqeifDLSKNGTTII 186
Cdd:COG1245  241 SYLDiyqRLNvARLIR----ELAEEGKYVL 266
CFTR_protein TIGR01271
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...
 21-227 3.52e-10

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]


Pssm-ID: 273530 [Multi-domain]  Cd Length: 1490  Bit Score: 61.08  E-value: 3.52e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152    21 DISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGR-PFDPQTDihaiGYMPeerGLYKkmkvgEQALYla 99
Cdd:TIGR01271  444 NISFKLEKGQLLAVAGSTGSGKSSLLMMIMGELEPSEGKIKHSGRiSFSPQTS----WIMP---GTIK-----DNIIF-- 509

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   100 qlkGMSerdakdkikywFDKFEINSWYNK-KVEE-------------------LSKGMQQKVQFISTIMHSPDLLILDEP 159
Cdd:TIGR01271  510 ---GLS-----------YDEYRYTSVIKAcQLEEdialfpekdktvlgeggitLSGGQRARISLARAVYKDADLYLLDSP 575

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 256041152   160 FSGLDPinanLIKQEIFD-----LSKNGTTIIFsTHRMEQVEEiCDRIVLVNQGKKLLDG---EVKQIKQDFKQHL 227
Cdd:TIGR01271  576 FTHLDV----VTEKEIFEsclckLMSNKTRILV-TSKLEHLKK-ADKILLLHEGVCYFYGtfsELQAKRPDFSSLL 645
ABC_RNaseL_inhibitor_domain1 cd03236
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
 26-190 3.97e-10

The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213203 [Multi-domain]  Cd Length: 255  Bit Score: 59.30  E-value: 3.97e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  26 IPK-GSIFGLLGPNGAGKTTLLRMITGIFYPDKG---------EILFNGRPFDPQTdihaigYMpeERGLYKKMKVGEQA 95
Cdd:cd03236   22 VPReGQVLGLVGPNGIGKSTALKILAGKLKPNLGkfddppdwdEILDEFRGSELQN------YF--TKLLEGDVKVIVKP 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  96 LYL----AQLKG-----MSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEPFSGLDpi 166
Cdd:cd03236   94 QYVdlipKAVKGkvgelLKKKDERGKLDELVDQLELRHVLDRNIDQLSGGELQRVAIAAALARDADFYFFDEPSSYLD-- 171

                        170       180       190
                 ....*....|....*....|....*....|
gi 256041152 167 nanlIKQE------IFDLSKNGTTIIFSTH 190
Cdd:cd03236  172 ----IKQRlnaarlIRELAEDDNYVLVVEH 197
ycf16 CHL00131
sulfate ABC transporter protein; Validated
 2-190 4.17e-10

sulfate ABC transporter protein; Validated


Pssm-ID: 214372 [Multi-domain]  Cd Length: 252  Bit Score: 59.27  E-value: 4.17e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   2 NLIEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGifYPD----KGEILFNGRP---FDPQTDIH 74
Cdd:CHL00131   6 PILEIKNLHASVNENEILKGLNLSINKGEIHAIMGPNGSGKSTLSKVIAG--HPAykilEGDILFKGESildLEPEERAH 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  75 -----AIGYMPEERGLykkmkVGEQALYLA-----QLKGMSERDAKDKIKYWFDKFEI----NSWYNKKVEE-LSKGMQQ 139
Cdd:CHL00131  84 lgiflAFQYPIEIPGV-----SNADFLRLAynskrKFQGLPELDPLEFLEIINEKLKLvgmdPSFLSRNVNEgFSGGEKK 158

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 256041152 140 KVQFISTIMHSPDLLILDEPFSGLDpINA-NLIKQEIFDLSKNGTTIIFSTH 190
Cdd:CHL00131 159 RNEILQMALLDSELAILDETDSGLD-IDAlKIIAEGINKLMTSENSIILITH 209
PRK11176 PRK11176
lipid A ABC transporter ATP-binding protein/permease MsbA;
4-233 4.57e-10

lipid A ABC transporter ATP-binding protein/permease MsbA;


Pssm-ID: 183016 [Multi-domain]  Cd Length: 582  Bit Score: 60.42  E-value: 4.57e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYAT--HKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDPQT---------- 71
Cdd:PRK11176 342 IEFRNVTFTYPGkeVPALRNINFKIPAGKTVALVGRSGSGKSTIANLLTRFYDIDEGEILLDGHDLRDYTlaslrnqval 421

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  72 ---DIHA--------IGYMPEERglYKKMKVgEQALYLAQlkGMserDAKDKIKYWFDKFeinswynkkVEE----LSKG 136
Cdd:PRK11176 422 vsqNVHLfndtiannIAYARTEQ--YSREQI-EEAARMAY--AM---DFINKMDNGLDTV---------IGEngvlLSGG 484

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 137 MQQKVQFISTIMHSPDLLILDEPFSGLDPINANLIKQEIFDLSKNGTTIIFStHRMEQVEEiCDRIVLVNQGKKLLDGEV 216
Cdd:PRK11176 485 QRQRIAIARALLRDSPILILDEATSALDTESERAIQAALDELQKNRTSLVIA-HRLSTIEK-ADEILVVEDGEIVERGTH 562

                        250       260
                 ....*....|....*....|
gi 256041152 217 KQ-IKQD--FKQhLFRIGFG 233
Cdd:PRK11176 563 AElLAQNgvYAQ-LHKMQFG 581
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
 18-219 5.54e-10

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 60.25  E-value: 5.54e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  18 AVDDISFAIPKGSIFGLLGPNGAGKT----TLLRMIT---GIFYPDK-------GEILFNGRPFDPQ------TDIHAIG 77
Cdd:PRK10261  31 AVRNLSFSLQRGETLAIVGESGSGKSvtalALMRLLEqagGLVQCDKmllrrrsRQVIELSEQSAAQmrhvrgADMAMIF 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  78 YMPEErGLYKKMKVGEQALYLAQL-KGMSERDAKDKIKYWFDKFEI---NSWYNKKVEELSKGMQQKVQFISTIMHSPDL 153
Cdd:PRK10261 111 QEPMT-SLNPVFTVGEQIAESIRLhQGASREEAMVEAKRMLDQVRIpeaQTILSRYPHQLSGGMRQRVMIAMALSCRPAV 189

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 256041152 154 LILDEPFSGLDPINANLIKQEIFDLSKNGTT-IIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQI 219
Cdd:PRK10261 190 LIADEPTTALDVTIQAQILQLIKVLQKEMSMgVIFITHDMGVVAEIADRVLVMYQGEAVETGSVEQI 256
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
 1-209 5.98e-10

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 60.10  E-value: 5.98e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   1 MNLIEIKHL----YKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKT----TLLRMITG--IFYPdKGEILFNGrpfdpQ 70
Cdd:PRK15134   3 QPLLAIENLsvafRQQQTVRTVVNDVSLQIEAGETLALVGESGSGKSvtalSILRLLPSppVVYP-SGDIRFHG-----E 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  71 TDIHAigYMPEERGL--------YKKMKVG-------EQALY--LAQLKGMSERDAKDKIKYWFDKFEINSWYNKKVE-- 131
Cdd:PRK15134  77 SLLHA--SEQTLRGVrgnkiamiFQEPMVSlnplhtlEKQLYevLSLHRGMRREAARGEILNCLDRVGIRQAAKRLTDyp 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 132 -ELSKGMQQKVQFISTIMHSPDLLILDEPFSGLD-PINANL------IKQEIfdlsknGTTIIFSTHRMEQVEEICDRIV 203
Cdd:PRK15134 155 hQLSGGERQRVMIAMALLTRPELLIADEPTTALDvSVQAQIlqllreLQQEL------NMGLLFITHNLSIVRKLADRVA 228


                 ....*.
gi 256041152 204 LVNQGK 209
Cdd:PRK15134 229 VMQNGR 234
PTZ00265 PTZ00265
multidrug resistance protein (mdr1); Provisional
 4-209 7.66e-10

multidrug resistance protein (mdr1); Provisional


Pssm-ID: 240339 [Multi-domain]  Cd Length: 1466  Bit Score: 60.04  E-value: 7.66e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152    4 IEIKHLYKHYATHKAVD---DISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNgrpfDPQT--DIH---- 74
Cdd:PTZ00265  383 IQFKNVRFHYDTRKDVEiykDLNFTLTEGKTYAFVGESGCGKSTILKLIERLYDPTEGDIIIN----DSHNlkDINlkww 458

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   75 --AIGYMPEERGLYK---KMKVGEQALYLAQLKGMSERDAKDKIKYWFDKFEINSW------------------------ 125
Cdd:PTZ00265  459 rsKIGVVSQDPLLFSnsiKNNIKYSLYSLKDLEALSNYYNEDGNDSQENKNKRNSCrakcagdlndmsnttdsneliemr 538

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  126 --YN-----------KKV---------------------EELSKGMQQKVQFISTIMHSPDLLILDEPFSGLDPINANLI 171
Cdd:PTZ00265  539 knYQtikdsevvdvsKKVlihdfvsalpdkyetlvgsnaSKLSGGQKQRISIARAIIRNPKILILDEATSSLDNKSEYLV 618

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|
gi 256041152  172 KQEIFDL--SKNGTTIIFStHRMEQVEEICDRIVLVNQGK 209
Cdd:PTZ00265  619 QKTINNLkgNENRITIIIA-HRLSTIRYANTIFVLSNRER 657
GguA NF040905
sugar ABC transporter ATP-binding protein;
3-222 8.69e-10

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 59.42  E-value: 8.69e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   3 LIEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIfYPD---KGEILFNGRP--FDpqtDIHAig 77
Cdd:NF040905   1 ILEMRGITKTFPGVKALDDVNLSVREGEIHALCGENGAGKSTLMKVLSGV-YPHgsyEGEILFDGEVcrFK---DIRD-- 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  78 ymPEERG---------LYKKMKVGEQaLYLA--QLKGM------SERDAKDKIKywfdKFEINSWYNKKVEELSKGMQQK 140
Cdd:NF040905  75 --SEALGiviihqelaLIPYLSIAEN-IFLGneRAKRGvidwneTNRRARELLA----KVGLDESPDTLVTDIGVGKQQL 147

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 141 VQFISTIMHSPDLLILDEPFSGL-DPINANLIKQeIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVNQGK--KLLDGEVK 217
Cdd:NF040905 148 VEIAKALSKDVKLLILDEPTAALnEEDSAALLDL-LLELKAQGITSIIISHKLNEIRRVADSITVLRDGRtiETLDCRAD 226


                 ....*
gi 256041152 218 QIKQD 222
Cdd:NF040905 227 EVTED 231
CFTR_protein TIGR01271
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...
 19-223 1.06e-09

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]


Pssm-ID: 273530 [Multi-domain]  Cd Length: 1490  Bit Score: 59.54  E-value: 1.06e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152    19 VDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDkGEILFNGRPFDP---QTDIHAIGYMPEERGLYK---KMKVG 92
Cdd:TIGR01271 1235 LQDLSFSVEGGQRVGLLGRTGSGKSTLLSALLRLLSTE-GEIQIDGVSWNSvtlQTWRKAFGVIPQKVFIFSgtfRKNLD 1313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152    93 EQALYLAQ--LKGMSERDAKDKIKYWFDKFEINSWYNKKVeeLSKGMQQKVQFISTIMHSPDLLILDEPFSGLDPINANL 170
Cdd:TIGR01271 1314 PYEQWSDEeiWKVAEEVGLKSVIEQFPDKLDFVLVDGGYV--LSNGHKQLMCLARSILSKAKILLLDEPSAHLDPVTLQI 1391

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 256041152   171 IKQEIFDLSKNgTTIIFSTHRMEQVEEiCDRIVLVNQGK--------KLLDgEVKQIKQDF 223
Cdd:TIGR01271 1392 IRKTLKQSFSN-CTVILSEHRVEALLE-CQQFLVIEGSSvkqydsiqKLLN-ETSLFKQAM 1449
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
 6-164 1.09e-09

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 59.18  E-value: 1.09e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152    6 IKHLYKHYATHKAV-DDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIfypDKGeilFNGRPFdPQTDIhAIGYMPEERG 84
Cdd:TIGR03719   7 MNRVSKVVPPKKEIlKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGV---DKD---FNGEAR-PQPGI-KVGYLPQEPQ 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   85 LYKKMKVGE----------------QALYLAqlkgMSERDAK------------DKIKYWfDKFEINS------------ 124
Cdd:TIGR03719  79 LDPTKTVREnveegvaeikdaldrfNEISAK----YAEPDADfdklaaeqaelqEIIDAA-DAWDLDSqleiamdalrcp 153

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 256041152  125 -WyNKKVEELSKGMQQKVQFISTIMHSPDLLILDEPFSGLD 164
Cdd:TIGR03719 154 pW-DADVTKLSGGERRRVALCRLLLSKPDMLLLDEPTNHLD 193
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
 26-164 1.35e-09

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 59.03  E-value: 1.35e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  26 IPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRpfdpqtdihaIGYMPEerglykkmkvgeqalYLAQLKGMS 105
Cdd:COG1245  363 IREGEVLGIVGPNGIGKTTFAKILAGVLKPDEGEVDEDLK----------ISYKPQ---------------YISPDYDGT 417

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 106 ERD-----AKDKI--KYW----FDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEPFSGLD 164
Cdd:COG1245  418 VEEflrsaNTDDFgsSYYkteiIKPLGLEKLLDKNVKDLSGGELQRVAIAACLSRDADLYLLDEPSAHLD 487
PRK15093 PRK15093
peptide ABC transporter ATP-binding protein SapD;
1-244 1.53e-09

peptide ABC transporter ATP-binding protein SapD;


Pssm-ID: 185049 [Multi-domain]  Cd Length: 330  Bit Score: 58.28  E-value: 1.53e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   1 MNLIEIKHLYKHYATH----KAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIfYPDKGEILFNGRPFDpqtDIHAI 76
Cdd:PRK15093   1 MPLLDIRNLTIEFKTSdgwvKAVDRVSMTLTEGEIRGLVGESGSGKSLIAKAICGV-TKDNWRVTADRMRFD---DIDLL 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  77 GYMPEERglyKKMkVGEQALYLAQLKGM----SERDAKDKIK---------YWFDKFeinSWYNKK-VE----------- 131
Cdd:PRK15093  77 RLSPRER---RKL-VGHNVSMIFQEPQScldpSERVGRQLMQnipgwtykgRWWQRF---GWRKRRaIEllhrvgikdhk 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 132 --------ELSKGMQQKVQFISTIMHSPDLLILDEPFSGLDPINanliKQEIFDL-----SKNGTTIIFSTHRMEQVEEI 198
Cdd:PRK15093 150 damrsfpyELTEGECQKVMIAIALANQPRLLIADEPTNAMEPTT----QAQIFRLltrlnQNNNTTILLISHDLQMLSQW 225

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 256041152 199 CDRIVLVNQGKKLLDGEVKQI----KQDFKQHLFRigfgVMPNFAQVATH 244
Cdd:PRK15093 226 ADKINVLYCGQTVETAPSKELvttpHHPYTQALIR----AIPDFGSAMPH 271
PRK10253 PRK10253
iron-enterobactin ABC transporter ATP-binding protein;
13-219 1.64e-09

iron-enterobactin ABC transporter ATP-binding protein;


Pssm-ID: 182336 [Multi-domain]  Cd Length: 265  Bit Score: 57.69  E-value: 1.64e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  13 YATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNG---RPFDPQTDIHAIGYMPEERGLYKKM 89
Cdd:PRK10253  17 YGKYTVAENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLDGehiQHYASKEVARRIGLLAQNATTPGDI 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  90 KVGE---QALYLAQ-LKGMSERDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEPFSGLDP 165
Cdd:PRK10253  97 TVQElvaRGRYPHQpLFTRWRKEDEEAVTKAMQATGITHLADQSVDTLSGGQRQRAWIAMVLAQETAIMLLDEPTTWLDI 176

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 256041152 166 INANLIKQEIFDLSK-NGTTIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQI 219
Cdd:PRK10253 177 SHQIDLLELLSELNReKGYTLAAVLHDLNQACRYASHLIALREGKIVAQGAPKEI 231
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
26-186 1.83e-09

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 58.67  E-value: 1.83e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  26 IPK-GSIFGLLGPNGAGKTTLLRMITGIFYPDKG---------EIL--FNGrpfdpqTDIHAigYMpeeRGLY-KKMKVG 92
Cdd:PRK13409  95 IPKeGKVTGILGPNGIGKTTAVKILSGELIPNLGdyeeepswdEVLkrFRG------TELQN--YF---KKLYnGEIKVV 163

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  93 EQALYLAQ------------LKGMSERDAKDKIKywfDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEPF 160
Cdd:PRK13409 164 HKPQYVDLipkvfkgkvrelLKKVDERGKLDEVV---ERLGLENILDRDISELSGGELQRVAIAAALLRDADFYFFDEPT 240

                        170       180       190
                 ....*....|....*....|....*....|
gi 256041152 161 SGLD---PIN-ANLIKqeifDLSKNGTTII 186
Cdd:PRK13409 241 SYLDirqRLNvARLIR----ELAEGKYVLV 266
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 28-204 2.95e-09

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 55.07  E-value: 2.95e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152    28 KGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFngrpFDPQTDIHAIGYMPEERGLYKKMKVGEQALYLaqlkgmseR 107
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPGGGVIY----IDGEDILEEVLDQLLLIIVGGKKASGSGELRL--------R 68

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   108 DAKDKIKYwfdkfeinswynkkveelskgmqqkvqfistimHSPDLLILDEPFSGLDPINANLIKQEIFD------LSKN 181
Cdd:smart00382  69 LALALARK---------------------------------LKPDVLILDEITSLLDAEQEALLLLLEELrlllllKSEK 115

                          170       180
                   ....*....|....*....|...
gi 256041152   182 GTTIIFSTHRMEQVEEICDRIVL 204
Cdd:smart00382 116 NLTVILTTNDEKDLGPALLRRRF 138
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
 18-209 3.87e-09

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 57.56  E-value: 3.87e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  18 AVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFDP---------QTDIHAIGYMPEErGLYKK 88
Cdd:PRK10261 339 AVEKVSFDLWPGETLSLVGESGSGKSTTGRALLRLVESQGGEIIFNGQRIDTlspgklqalRRDIQFIFQDPYA-SLDPR 417

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  89 MKVGEQALYLAQLKGMSERDAKDKIKYWFDK----FEINSWynKKVEELSKGMQQKVQFISTIMHSPDLLILDEPFSGLD 164
Cdd:PRK10261 418 QTVGDSIMEPLRVHGLLPGKAAAARVAWLLErvglLPEHAW--RYPHEFSGGQRQRICIARALALNPKVIIADEAVSALD 495

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 256041152 165 -PINANLIKQeIFDLSKN-GTTIIFSTHRMEQVEEICDRIVLVNQGK 209
Cdd:PRK10261 496 vSIRGQIINL-LLDLQRDfGIAYLFISHDMAVVERISHRVAVMYLGQ 541
PRK15112 PRK15112
peptide ABC transporter ATP-binding protein SapF;
3-209 4.40e-09

peptide ABC transporter ATP-binding protein SapF;


Pssm-ID: 185067 [Multi-domain]  Cd Length: 267  Bit Score: 56.34  E-value: 4.40e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   3 LIEIKHLYK---------HYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPF------ 67
Cdd:PRK15112   4 LLEVRNLSKtfryrtgwfRRQTVEAVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELLIDDHPLhfgdys 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  68 -----------DPQTDIHaigymPEERglykkmkVGEqaLYLAQLKGMSERDAKDKIKYWFDKFE----INSWYNKKVEE 132
Cdd:PRK15112  84 yrsqrirmifqDPSTSLN-----PRQR-------ISQ--ILDFPLRLNTDLEPEQREKQIIETLRqvglLPDHASYYPHM 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 133 LSKGMQQKVQFISTIMHSPDLLILDEPFSGLDP------INANLIKQEifdlsKNGTTIIFSTHRMEQVEEICDRIVLVN 206
Cdd:PRK15112 150 LAPGQKQRLGLARALILRPKVIIADEALASLDMsmrsqlINLMLELQE-----KQGISYIYVTQHLGMMKHISDQVLVMH 224


                 ...
gi 256041152 207 QGK 209
Cdd:PRK15112 225 QGE 227
PRK10938 PRK10938
putative molybdenum transport ATP-binding protein ModF; Provisional
 119-210 5.49e-09

putative molybdenum transport ATP-binding protein ModF; Provisional


Pssm-ID: 182852 [Multi-domain]  Cd Length: 490  Bit Score: 56.95  E-value: 5.49e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 119 KFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILDEPFSGLDPINANLIKQEIFDLSKNGTTIIFSTHRMEQVEEI 198
Cdd:PRK10938 122 QFGITALLDRRFKYLSTGETRKTLLCQALMSEPDLLILDEPFDGLDVASRQQLAELLASLHQSGITLVLVLNRFDEIPDF 201

                         90
                 ....*....|....*...
gi 256041152 199 CDRI------VLVNQGKK 210
Cdd:PRK10938 202 VQFAgvladcTLAETGER 219
ABCC_MRP_domain2 cd03244
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ...
 4-209 7.13e-09

ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213211 [Multi-domain]  Cd Length: 221  Bit Score: 55.19  E-value: 7.13e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYATHK--AVDDISFAIPKGSIFGLLGPNGAGKTT----LLRMITgifyPDKGEILFNGRP---FDPQTDIH 74
Cdd:cd03244    3 IEFKNVSLRYRPNLppVLKNISFSIKPGEKVGIVGRTGSGKSSlllaLFRLVE----LSSGSILIDGVDiskIGLHDLRS 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  75 AIGYMPEE--------------RGLYKKMKVgEQALYLAQLKGMSERDAKDKikywfdkfeinswyNKKVEE----LSKG 136
Cdd:cd03244   79 RISIIPQDpvlfsgtirsnldpFGEYSDEEL-WQALERVGLKEFVESLPGGL--------------DTVVEEggenLSVG 143

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 256041152 137 MQQKVQFISTIMHSPDLLILDEPFSGLDPINANLIKQEIFDLSKNgTTIIFSTHRMEQVEEiCDRIVLVNQGK 209
Cdd:cd03244  144 QRQLLCLARALLRKSKILVLDEATASVDPETDALIQKTIREAFKD-CTVLTIAHRLDTIID-SDRILVLDKGR 214
PRK11147 PRK11147
ABC transporter ATPase component; Reviewed
 1-209 7.82e-09

ABC transporter ATPase component; Reviewed


Pssm-ID: 236861 [Multi-domain]  Cd Length: 635  Bit Score: 56.50  E-value: 7.82e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   1 MNLIEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGR------PFDPQTDI- 73
Cdd:PRK11147   1 MSLISIHGAWLSFSDAPLLDNAELHIEDNERVCLVGRNGAGKSTLMKILNGEVLLDDGRIIYEQDlivarlQQDPPRNVe 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  74 ---------------------HAIGYM----PEERGLYKKMKVGEQA--LYLAQLkgmserdaKDKIKYWFDKFEINSwy 126
Cdd:PRK11147  81 gtvydfvaegieeqaeylkryHDISHLvetdPSEKNLNELAKLQEQLdhHNLWQL--------ENRINEVLAQLGLDP-- 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 127 NKKVEELSKGMQQKVQFISTIMHSPDLLILDEPFSGLDpINAnlIKQ-EIFDLSKNGtTIIFSTHRMEQVEEICDRIVLV 205
Cdd:PRK11147 151 DAALSSLSGGWLRKAALGRALVSNPDVLLLDEPTNHLD-IET--IEWlEGFLKTFQG-SIIFISHDRSFIRNMATRIVDL 226


                 ....
gi 256041152 206 NQGK 209
Cdd:PRK11147 227 DRGK 230
PRK10790 PRK10790
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
4-219 1.53e-08

SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;


Pssm-ID: 182733 [Multi-domain]  Cd Length: 592  Bit Score: 55.88  E-value: 1.53e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   4 IEIKHLYKHYATHKAV-DDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNGRPFdpQTDIHAI----GY 78
Cdd:PRK10790 341 IDIDNVSFAYRDDNLVlQNINLSVPSRGFVALVGHTGSGKSTLASLLMGYYPLTEGEIRLDGRPL--SSLSHSVlrqgVA 418

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  79 MPEE------RGLYKKMKVGE--------QALYLAQL----KGMSErdakdkikywfdkfEINSWYNKKVEELSKGMQQK 140
Cdd:PRK10790 419 MVQQdpvvlaDTFLANVTLGRdiseeqvwQALETVQLaelaRSLPD--------------GLYTPLGEQGNNLSVGQKQL 484

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 256041152 141 VQFISTIMHSPDLLILDEPFSGLDPINANLIKQEIFDLSKNgTTIIFSTHRMEQVEEiCDRIVLVNQGKKLLDGEVKQI 219
Cdd:PRK10790 485 LALARVLVQTPQILILDEATANIDSGTEQAIQQALAAVREH-TTLVVIAHRLSTIVE-ADTILVLHRGQAVEQGTHQQL 561
3a01203 TIGR00954
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, ...
 19-191 2.39e-08

Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 273360 [Multi-domain]  Cd Length: 659  Bit Score: 55.14  E-value: 2.39e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   19 VDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIfYPdkgeiLFNGRPFDPQTDihAIGYMPEErglyKKMKVG---EQA 95
Cdd:TIGR00954 468 IESLSFEVPSGNNLLICGPNGCGKSSLFRILGEL-WP-----VYGGRLTKPAKG--KLFYVPQR----PYMTLGtlrDQI 535

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   96 LYLAQLKGMSERDAKDK-IKYWFDKFEINSWYNKKV---------EELSKGMQQKVQFISTIMHSPDLLILDEPFSGLDP 165
Cdd:TIGR00954 536 IYPDSSEDMKRRGLSDKdLEQILDNVQLTHILEREGgwsavqdwmDVLSGGEKQRIAMARLFYHKPQFAILDECTSAVSV 615

                         170       180
                  ....*....|....*....|....*..
gi 256041152  166 InanlIKQEIFDLSKN-GTTIIFSTHR 191
Cdd:TIGR00954 616 D----VEGYMYRLCREfGITLFSVSHR 638
hmuV PRK13547
heme ABC transporter ATP-binding protein;
3-221 2.83e-08

heme ABC transporter ATP-binding protein;


Pssm-ID: 184132 [Multi-domain]  Cd Length: 272  Bit Score: 54.06  E-value: 2.83e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   3 LIEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPD--------KGEILFNGRPFD------ 68
Cdd:PRK13547   1 MLTADHLHVARRHRAILRDLSLRIEPGRVTALLGRNGAGKSTLLKALAGDLTGGgaprgarvTGDVTLNGEPLAaidapr 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  69 --------PQT----------DIHAIGYMPEER----GLYKKMKVGEQALYLAQLKGMSERDakdkikywfdkfeinswy 126
Cdd:PRK13547  81 larlravlPQAaqpafafsarEIVLLGRYPHARragaLTHRDGEIAWQALALAGATALVGRD------------------ 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 127 nkkVEELSKGMQQKVQFISTI---------MHSPDLLILDEPFSGLDPINANLIKQEIFDLSKN---GTTIIfsTHRMEQ 194
Cdd:PRK13547 143 ---VTTLSGGELARVQFARVLaqlwpphdaAQPPRYLLLDEPTAALDLAHQHRLLDTVRRLARDwnlGVLAI--VHDPNL 217

                        250       260
                 ....*....|....*....|....*..
gi 256041152 195 VEEICDRIVLVNQGKKLLDGEVKQIKQ 221
Cdd:PRK13547 218 AARHADRIAMLADGAIVAHGAPADVLT 244
ABC_Class2 cd03227
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ...
 11-203 2.77e-07

ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.


Pssm-ID: 213194 [Multi-domain]  Cd Length: 162  Bit Score: 49.67  E-value: 2.77e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  11 KHYATHKAVDDISFaiPKGSIFGLLGPNGAGKTTLLRmitgifypdkgeilfngrpfdpqtdihAIGYmpeerglykkmk 90
Cdd:cd03227    5 GRFPSYFVPNDVTF--GEGSLTIITGPNGSGKSTILD---------------------------AIGL------------ 43

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  91 vgeqALYLAQLKGMSERDAKDKIKYWFDKFEINSwynkKVEELSKGMQQKVQfISTIMH-----SPDLLILDEPFSGLDP 165
Cdd:cd03227   44 ----ALGGAQSATRRRSGVKAGCIVAAVSAELIF----TRLQLSGGEKELSA-LALILAlaslkPRPLYILDEIDRGLDP 114

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 256041152 166 INANLIKQEIFDLSKNGTTIIFSTHRmEQVEEICDRIV 203
Cdd:cd03227  115 RDGQALAEAILEHLVKGAQVIVITHL-PELAELADKLI 151
ABCG_PDR_domain1 cd03233
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ...
 15-209 4.63e-07

First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213200 [Multi-domain]  Cd Length: 202  Bit Score: 49.57  E-value: 4.63e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  15 THKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGI---FYPDKGEILFNGRPFDPQTDIH--AIGYMPEERGLYKKM 89
Cdd:cd03233   19 KIPILKDFSGVVKPGEMVLVLGRPGSGCSTLLKALANRtegNVSVEGDIHYNGIPYKEFAEKYpgEIIYVSEEDVHFPTL 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  90 KVGEQALYLAQLKGmserdakdkikywfdkfeinswyNKKVEELSKGMQQKVQFISTIMHSPDLLILDEPFSGLDPINAN 169
Cdd:cd03233   99 TVRETLDFALRCKG-----------------------NEFVRGISGGERKRVSIAEALVSRASVLCWDNSTRGLDSSTAL 155

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 256041152 170 LIKQEIFDLSK--NGTTIIFSTHRMEQVEEICDRIVLVNQGK 209
Cdd:cd03233  156 EILKCIRTMADvlKTTTFVSLYQASDEIYDLFDKVLVLYEGR 197
PTZ00265 PTZ00265
multidrug resistance protein (mdr1); Provisional
 85-206 5.13e-07

multidrug resistance protein (mdr1); Provisional


Pssm-ID: 240339 [Multi-domain]  Cd Length: 1466  Bit Score: 51.18  E-value: 5.13e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   85 LYKKMKVGEQALYLAQLKGMSERDAKDK-IKYWFDKFEIN-SWYNKkveELSKGMQQKVQFISTIMHSPDLLILDEPFSG 162
Cdd:PTZ00265 1312 IYENIKFGKEDATREDVKRACKFAAIDEfIESLPNKYDTNvGPYGK---SLSGGQKQRIAIARALLREPKILLLDEATSS 1388

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 256041152  163 LDPINANLIKQEIFDLS-KNGTTIIFSTHRMEQVEEiCDRIVLVN 206
Cdd:PTZ00265 1389 LDSNSEKLIEKTIVDIKdKADKTIITIAHRIASIKR-SDKIVVFN 1432
ABC_UvrA cd03238
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in ...
 14-216 6.33e-07

ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.


Pssm-ID: 213205 [Multi-domain]  Cd Length: 176  Bit Score: 48.86  E-value: 6.33e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  14 ATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRmitGIFYPDKGEILFNGRPFDPQTDIHAIGympeerglykkmkvge 93
Cdd:cd03238    6 ANVHNLQNLDVSIPLNVLVVVTGVSGSGKSTLVN---EGLYASGKARLISFLPKFSRNKLIFID---------------- 66

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  94 qalylaQLKGMSerdakdkikywfdkfEINSWY---NKKVEELSKGMQQKVQFISTIMHSPD--LLILDEPFSGLDPINA 168
Cdd:cd03238   67 ------QLQFLI---------------DVGLGYltlGQKLSTLSGGELQRVKLASELFSEPPgtLFILDEPSTGLHQQDI 125

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 256041152 169 NLIKQEIFDLSKNGTTIIFSTHRmEQVEEICDRIVLVNQGKKLLDGEV 216
Cdd:cd03238  126 NQLLEVIKGLIDLGNTVILIEHN-LDVLSSADWIIDFGPGSGKSGGKV 172
PRK10636 PRK10636
putative ABC transporter ATP-binding protein; Provisional
 3-227 1.52e-06

putative ABC transporter ATP-binding protein; Provisional


Pssm-ID: 236729 [Multi-domain]  Cd Length: 638  Bit Score: 49.78  E-value: 1.52e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   3 LIEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEIlfngrpfdpqtdihaigympee 82
Cdd:PRK10636 312 LLKMEKVSAGYGDRIILDSIKLNLVPGSRIGLLGRNGAGKSTLIKLLAGELAPVSGEI---------------------- 369

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  83 rGLYKKMKVGeqalYLAQ---------------LKGMSERDAKDKIKYWFDKFeinSWYNKKVEE----LSKGMQQKVQF 143
Cdd:PRK10636 370 -GLAKGIKLG----YFAQhqleflradesplqhLARLAPQELEQKLRDYLGGF---GFQGDKVTEetrrFSGGEKARLVL 441

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 144 ISTIMHSPDLLILDEPFSGLDPINANLIKQEIFDLskNGTTIIFStHRMEQVEEICDRIVLVNQGK-KLLDGEVkqikQD 222
Cdd:PRK10636 442 ALIVWQRPNLLLLDEPTNHLDLDMRQALTEALIDF--EGALVVVS-HDRHLLRSTTDDLYLVHDGKvEPFDGDL----ED 514


                 ....*
gi 256041152 223 FKQHL 227
Cdd:PRK10636 515 YQQWL 519
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
 20-164 2.86e-06

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 48.58  E-value: 2.86e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  20 DDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIfypDKGeilFNGRPFdPQTDIhAIGYMPEERGLYK--------KMKV 91
Cdd:PRK11819  24 KDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGV---DKE---FEGEAR-PAPGI-KVGYLPQEPQLDPektvrenvEEGV 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  92 GEQALYLAQLKG----MSERDAK------------DKIKYWfDKFEINS-------------WyNKKVEELSKGMQQKVQ 142
Cdd:PRK11819  96 AEVKAALDRFNEiyaaYAEPDADfdalaaeqgelqEIIDAA-DAWDLDSqleiamdalrcppW-DAKVTKLSGGERRRVA 173

                        170       180
                 ....*....|....*....|..
gi 256041152 143 FISTIMHSPDLLILDEPFSGLD 164
Cdd:PRK11819 174 LCRLLLEKPDMLLLDEPTNHLD 195
AAA_21 pfam13304
AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being ...
 132-190 6.65e-06

AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being of the abortive phage resistance system, in which case the family would be acting as the toxin for a type IV toxin-antitoxin resistance system.


Pssm-ID: 433102 [Multi-domain]  Cd Length: 303  Bit Score: 47.00  E-value: 6.65e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 256041152  132 ELSKGMQQKVQFISTIM---HSPDLLILDEPFSGLDPINANLIKQEIFDLSKNGTTIIFSTH 190
Cdd:pfam13304 236 ELSDGTKRLLALLAALLsalPKGGLLLIDEPESGLHPKLLRRLLELLKELSRNGAQLILTTH 297
PRK11147 PRK11147
ABC transporter ATPase component; Reviewed
 5-60 9.78e-06

ABC transporter ATPase component; Reviewed


Pssm-ID: 236861 [Multi-domain]  Cd Length: 635  Bit Score: 46.87  E-value: 9.78e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 256041152   5 EIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEI 60
Cdd:PRK11147 321 EMENVNYQIDGKQLVKDFSAQVQRGDKIALIGPNGCGKTTLLKLMLGQLQADSGRI 376
PRK10636 PRK10636
putative ABC transporter ATP-binding protein; Provisional
 19-207 1.46e-05

putative ABC transporter ATP-binding protein; Provisional


Pssm-ID: 236729 [Multi-domain]  Cd Length: 638  Bit Score: 46.70  E-value: 1.46e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  19 VDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNG-------RPFDPQTDIHAIGYMPEERGLYKKMKv 91
Cdd:PRK10636  17 LDNATATINPGQKVGLVGKNGCGKSTLLALLKNEISADGGSYTFPGnwqlawvNQETPALPQPALEYVIDGDREYRQLE- 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  92 geqalylAQLKGMSERDAKDKIKYWFDKFE-INSW-------------------YNKKVEELSKGMQQKVQFISTIMHSP 151
Cdd:PRK10636  96 -------AQLHDANERNDGHAIATIHGKLDaIDAWtirsraasllhglgfsneqLERPVSDFSGGWRMRLNLAQALICRS 168

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 256041152 152 DLLILDEPFSGLDpINAnLIKQEIFDLSKNGTTIIFStHRMEQVEEICDRIVLVNQ 207
Cdd:PRK10636 169 DLLLLDEPTNHLD-LDA-VIWLEKWLKSYQGTLILIS-HDRDFLDPIVDKIIHIEQ 221
PLN03140 PLN03140
ABC transporter G family member; Provisional
 21-208 8.38e-05

ABC transporter G family member; Provisional


Pssm-ID: 215599 [Multi-domain]  Cd Length: 1470  Bit Score: 44.45  E-value: 8.38e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   21 DISFAIPKGSIFGLLGPNGAGKTTLLRMI----TGIF---------YPDKGEILFNGRPFDPQTDIH------------- 74
Cdd:PLN03140  898 EVTGAFRPGVLTALMGVSGAGKTTLMDVLagrkTGGYiegdirisgFPKKQETFARISGYCEQNDIHspqvtvresliys 977

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   75 AIGYMPEERGLYKKMKVGEQALYLAQLKGMserdaKDKIKYWfdkfeinswynKKVEELSKGMQQKVQFISTIMHSPDLL 154
Cdd:PLN03140  978 AFLRLPKEVSKEEKMMFVDEVMELVELDNL-----KDAIVGL-----------PGVTGLSTEQRKRLTIAVELVANPSII 1041

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 256041152  155 ILDEPFSGLDPINANLIKQEIFDLSKNGTTIIFSTHRME-QVEEICDRIVLVNQG 208
Cdd:PLN03140 1042 FMDEPTSGLDARAAAIVMRTVRNTVDTGRTVVCTIHQPSiDIFEAFDELLLMKRG 1096
sufC PRK09580
cysteine desulfurase ATPase component; Reviewed
 3-221 1.23e-04

cysteine desulfurase ATPase component; Reviewed


Pssm-ID: 181965 [Multi-domain]  Cd Length: 248  Bit Score: 42.86  E-value: 1.23e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   3 LIEIKHLYKHYATHKAVDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGI--FYPDKGEILFNGRPFdpqtdihaIGYMP 80
Cdd:PRK09580   1 MLSIKDLHVSVEDKAILRGLNLEVRPGEVHAIMGPNGSGKSTLSATLAGRedYEVTGGTVEFKGKDL--------LELSP 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  81 EER---GLYKKMKvgeqalYLAQLKGMSER----DAKDKIKYW-----FDKFEINSWYNKKVEEL--------------- 133
Cdd:PRK09580  73 EDRageGIFMAFQ------YPVEIPGVSNQfflqTALNAVRSYrgqepLDRFDFQDLMEEKIALLkmpedlltrsvnvgf 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 134 SKGMQQKVQFISTIMHSPDLLILDEPFSGLDPINANLIKQEIFDLSKNGTTIIFSTHRMEQVEEI-CDRIVLVNQGKKLL 212
Cdd:PRK09580 147 SGGEKKRNDILQMAVLEPELCILDESDSGLDIDALKIVADGVNSLRDGKRSFIIVTHYQRILDYIkPDYVHVLYQGRIVK 226


                 ....*....
gi 256041152 213 DGEVKQIKQ 221
Cdd:PRK09580 227 SGDFTLVKQ 235
YbjD COG3593
Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM ...
 17-241 1.33e-04

Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM domains [Replication, recombination and repair];


Pssm-ID: 442812 [Multi-domain]  Cd Length: 359  Bit Score: 43.07  E-value: 1.33e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  17 KAVDDISFAIPKGSIFgLLGPNGAGKTTLLRMITGIFYPDKGEIL------FNGRPFDPQTDIHAIGYMPEERGLYKKMK 90
Cdd:COG3593   12 RSIKDLSIELSDDLTV-LVGENNSGKSSILEALRLLLGPSSSRKFdeedfyLGDDPDLPEIEIELTFGSLLSRLLRLLLK 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  91 VGEQALYLAQLKGMSE------RDAKDKIKYWFDKF-------------EINSWYNK-----------KVEELSKGMQQK 140
Cdd:COG3593   91 EEDKEELEEALEELNEelkealKALNELLSEYLKELldgldlelelsldELEDLLKSlslriedgkelPLDRLGSGFQRL 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152 141 VQF--ISTIMH-----SPDLLILDEPFSGLDPINANLIKQEIFDLSKNGTTIIFSTHRMEQVEEIC-DRIVLVNQGKKll 212
Cdd:COG3593  171 ILLalLSALAElkrapANPILLIEEPEAHLHPQAQRRLLKLLKELSEKPNQVIITTHSPHLLSEVPlENIRRLRRDSG-- 248

                        250       260
                 ....*....|....*....|....*....
gi 256041152 213 DGEVKQIKQDFKQHLFRIGFGVMPNFAQV 241
Cdd:COG3593  249 GTTSTKLIDLDDEDLRKLLRYLGVTRSEL 277
COG3950 COG3950
Predicted ATP-binding protein involved in virulence [General function prediction only];
21-188 1.35e-04

Predicted ATP-binding protein involved in virulence [General function prediction only];


Pssm-ID: 443150 [Multi-domain]  Cd Length: 276  Bit Score: 42.68  E-value: 1.35e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  21 DISFAIPKGSIFgLLGPNGAGKTTLLRMITGIFYPDKGEI------LFNGRPFDPQTDIHAIGYMPEERGL-------YK 87
Cdd:COG3950   18 EIDFDNPPRLTV-LVGENGSGKTTLLEAIALALSGLLSRLddvkfrKLLIRNGEFGDSAKLILYYGTSRLLldgplkkLE 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  88 KMKvGEQALYLAQLKGMSERDAK-DKIKYWFDkfeinsWYNKKVEElsKGMQQKVQFISTIMHspdllILDEPFSGLDPI 166
Cdd:COG3950   97 RLK-EEYFSRLDGYDSLLDEDSNlREFLEWLR------EYLEDLEN--KLSDELDEKLEAVRE-----ALNKLLPDFKDI 162

                        170       180
                 ....*....|....*....|..
gi 256041152 167 NANLIKQEIFDLSKNGTTIIFS 188
Cdd:COG3950  163 RIDRDPGRLVILDKNGEELPLN 184
ABC_RNaseL_inhibitor cd03222
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ...
 26-64 1.98e-04

ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213189 [Multi-domain]  Cd Length: 177  Bit Score: 41.40  E-value: 1.98e-04
                         10        20        30
                 ....*....|....*....|....*....|....*....
gi 256041152  26 IPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEILFNG 64
Cdd:cd03222   22 VKEGEVIGIVGPNGTGKTTAVKILAGQLIPNGDNDEWDG 60
PRK00635 PRK00635
excinuclease ABC subunit A; Provisional
 127-216 6.04e-04

excinuclease ABC subunit A; Provisional


Pssm-ID: 234806 [Multi-domain]  Cd Length: 1809  Bit Score: 41.74  E-value: 6.04e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  127 NKKVEELSKGMQQKVQF-------ISTIMHspdllILDEPFSGLDPINANLIKQEIFDLSKNGTTIIFSTHRmEQVEEIC 199
Cdd:PRK00635  471 ERALATLSGGEQERTALakhlgaeLIGITY-----ILDEPSIGLHPQDTHKLINVIKKLRDQGNTVLLVEHD-EQMISLA 544

                          90
                  ....*....|....*..
gi 256041152  200 DRIVLVNQGKKLLDGEV 216
Cdd:PRK00635  545 DRIIDIGPGAGIFGGEV 561
PRK15177 PRK15177
Vi polysaccharide ABC transporter ATP-binding protein VexC;
19-226 8.00e-04

Vi polysaccharide ABC transporter ATP-binding protein VexC;


Pssm-ID: 185099 [Multi-domain]  Cd Length: 213  Bit Score: 40.04  E-value: 8.00e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  19 VDDISFAIPKGSIFGLLGPNGAGKTTLLRMITGIFYPDKGEIL---FNGRPFDPQTDIhaigyMPEERGlykkmkvGEQA 95
Cdd:PRK15177   3 LDKTDFVMGYHEHIGILAAPGSGKTTLTRLLCGLDAPDEGDFIglrGDALPLGANSFI-----LPGLTG-------EENA 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  96 LYLAQLKGMserDAKDKIKYWFDKFEINSWYNKKVEELSKGMQQKVQFISTIMHSPDLLILD-EPFSGLDPINANLIKQE 174
Cdd:PRK15177  71 RMMASLYGL---DGDEFSHFCYQLTQLEQCYTDRVSEYSVTMKTHLAFAINLLLPCRLYIADgKLYTGDNATQLRMQAAL 147

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 256041152 175 IFDLSKNGttIIFSTHRMEQVEEICDRIVLVNQGKKLLDGEVKQIKQDFKQH 226
Cdd:PRK15177 148 ACQLQQKG--LIVLTHNPRLIKEHCHAFGVLLHGKITMCEDLAQATALFEQY 197
SbcC COG0419
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair];
4-54 9.69e-04

DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair];


Pssm-ID: 440188 [Multi-domain]  Cd Length: 204  Bit Score: 39.61  E-value: 9.69e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 256041152   4 IEIKHLYKHYATHKavddISFAipkGSIFGLLGPNGAGKTTLLRMITGIFY 54
Cdd:COG0419    5 LRLENFRSYRDTET----IDFD---DGLNLIVGPNGAGKSTILEAIRYALY 48
AAA_21 pfam13304
AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being ...
 31-247 7.27e-03

AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being of the abortive phage resistance system, in which case the family would be acting as the toxin for a type IV toxin-antitoxin resistance system.


Pssm-ID: 433102 [Multi-domain]  Cd Length: 303  Bit Score: 37.75  E-value: 7.27e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   31 IFGLLGPNGAGKTTLLRMITGIFYPDKG-----------------EILFNGRPFDPQTDIHAIGYMPEERgLYKKMKVGE 93
Cdd:pfam13304   1 INVLIGPNGSGKSNLLEALRFLADFDALvigltdersrnggiggiPSLLNGIDPKEPIEFEISEFLEDGV-RYRYGLDLE 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152   94 QALYLAQLKGMSERDAKDKIKYWFDKFEINSWY-----NKKVEELSKGMQQKVQFISTIMHSPDLLILDEPFSGLDPINA 168
Cdd:pfam13304  80 REDVEEKLSSKPTLLEKRLLLREDSEEREPKFPpeaeeLRLGLDVEERIELSLSELSDLISGLLLLSIISPLSFLLLLDE 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256041152  169 NLIKqEIFDLSKNGTTIIFSTHRMEQVEEICDRIVLVN-QGKKLLDGEVKQIKQDFKQHLFRIGFGVMPNFAQVATHHFS 247
Cdd:pfam13304 160 GLLL-EDWAVLDLAADLALFPDLKELLQRLVRGLKLADlNLSDLGEGIEKSLLVDDRLRERGLILLENGGGGELPAFELS 238
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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