NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|260310440|gb|ACX36508|]
View 

MIP13364p [Drosophila melanogaster]

Protein Classification

EVI5 family protein( domain architecture ID 13892321)

EVI5 family protein similar to human ecotropic viral integration site 5 protein homolog (EVI5) that functions as a regulator of cell cycle progression by stabilizing the FBXO5 protein and promoting cyclin-A accumulation during interphase and may also play a role in cytokinesis

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
TBC smart00164
Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs; Widespread domain present in Gyp6 and ...
113-320 8.86e-72

Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs; Widespread domain present in Gyp6 and Gyp7, thereby giving rise to the notion that it performs a GTP-activator activity on Rab-like GTPases.


:

Pssm-ID: 214540 [Multi-domain]  Cd Length: 216  Bit Score: 233.74  E-value: 8.86e-72
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   113 VRRGIPHHFRAIVWQQLSGASD----GDKKQYAEYIKATSACEKV----IRRDIARTYPEVEFFKEKDGPGQEALFNVIK 184
Cdd:smart00164   1 VRKGVPPSLRGVVWKLLLNAQPmdtsADKDLYSRLLKETAPDDKSivhqIEKDLRRTFPEHSFFQDKEGPGQESLRRVLK 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   185 AYSLHDREVGYCQGSGFIVGLLLMQMP-EEEAFAVLVQIMQQHRMRhMFKPSMSELGLCMYQLENLVQEQIPDMHIHFQQ 263
Cdd:smart00164  81 AYALYNPEVGYCQGMNFLAAPLLLVMEdEEDAFWCLVKLMERYGPN-FYLPDMSGLQLDLLQLDRLVKEYDPDLYKHLKD 159
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 260310440   264 QGFQTTMYASSWFLTLYTTTLNVNLSCRIMDVFLSEGMEFIFKVALALLLTGKDTLL 320
Cdd:smart00164 160 LGITPSLYALRWFLTLFARELPLEIVLRIWDVLFAEGSDFLFRVALALLKLHRDVLL 216
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
358-755 2.77e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 76.90  E-value: 2.77e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 358 KRMKKMEKE------YQDLKKKEQEEMAELRRLRRENC-----LLKQRNELLEAESAELADRLVRGQVSRAEEEETSYAI 426
Cdd:COG1196  200 RQLEPLERQaekaerYRELKEELKELEAELLLLKLRELeaeleELEAELEELEAELEELEAELAELEAELEELRLELEEL 279
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 427 QTELMQLRRSYLEVSHQLENANEEVRGLSLRLQENNNSRQSSIDELCMKEEALKQRDEMVSCLLEELVKVRQGLAESEDQ 506
Cdd:COG1196  280 ELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAE 359
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 507 IRNLKAKVEELEEDKktlrettpdnsvAHLQDELIASKLREAEASLSLKDLKQRVQELSSQWQRQLAENQRSESERTTNA 586
Cdd:COG1196  360 LAEAEEALLEAEAEL------------AEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELE 427
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 587 vdstpkklltnffdsskssEHTQKLEEELMTTRIREMETLTELKELRLKVMELETQVQVSTNQLRRQDEEHKKLKEELEM 666
Cdd:COG1196  428 -------------------EALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAE 488
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 667 AVTREKDMSNKAREQQHRYSDLESRMKdelmnvKIKFTEQSQTVAELKQEISRLETKNSEMLAEGELRANLDDSDKVRDL 746
Cdd:COG1196  489 AAARLLLLLEAEADYEGFLEGVKAALL------LAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAA 562

                 ....*....
gi 260310440 747 QDRLADMKA 755
Cdd:COG1196  563 IEYLKAAKA 571
 
Name Accession Description Interval E-value
TBC smart00164
Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs; Widespread domain present in Gyp6 and ...
113-320 8.86e-72

Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs; Widespread domain present in Gyp6 and Gyp7, thereby giving rise to the notion that it performs a GTP-activator activity on Rab-like GTPases.


Pssm-ID: 214540 [Multi-domain]  Cd Length: 216  Bit Score: 233.74  E-value: 8.86e-72
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   113 VRRGIPHHFRAIVWQQLSGASD----GDKKQYAEYIKATSACEKV----IRRDIARTYPEVEFFKEKDGPGQEALFNVIK 184
Cdd:smart00164   1 VRKGVPPSLRGVVWKLLLNAQPmdtsADKDLYSRLLKETAPDDKSivhqIEKDLRRTFPEHSFFQDKEGPGQESLRRVLK 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   185 AYSLHDREVGYCQGSGFIVGLLLMQMP-EEEAFAVLVQIMQQHRMRhMFKPSMSELGLCMYQLENLVQEQIPDMHIHFQQ 263
Cdd:smart00164  81 AYALYNPEVGYCQGMNFLAAPLLLVMEdEEDAFWCLVKLMERYGPN-FYLPDMSGLQLDLLQLDRLVKEYDPDLYKHLKD 159
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 260310440   264 QGFQTTMYASSWFLTLYTTTLNVNLSCRIMDVFLSEGMEFIFKVALALLLTGKDTLL 320
Cdd:smart00164 160 LGITPSLYALRWFLTLFARELPLEIVLRIWDVLFAEGSDFLFRVALALLKLHRDVLL 216
RabGAP-TBC pfam00566
Rab-GTPase-TBC domain; Identification of a TBC domain in GYP6_YEAST and GYP7_YEAST, which are ...
154-320 3.32e-53

Rab-GTPase-TBC domain; Identification of a TBC domain in GYP6_YEAST and GYP7_YEAST, which are GTPase activator proteins of yeast Ypt6 and Ypt7, implies that these domains are GTPase activator proteins of Rab-like small GTPases.


Pssm-ID: 459855  Cd Length: 178  Bit Score: 182.07  E-value: 3.32e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  154 IRRDIARTYPEVEFFKekDGPGQEALFNVIKAYSLHDREVGYCQGSGFIVGLLLMQ-MPEEEAFAVLVQIMQQHRMRHMF 232
Cdd:pfam00566  12 IEKDVPRTFPHSFFFD--NGPGQNSLRRILKAYSIYNPDVGYCQGMNFIAAPLLLVyLDEEDAFWCFVSLLENYLLRDFY 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  233 KPSMSELGLCMYQLENLVQEQIPDMHIHFQQQGFQTTMYASSWFLTLYTTTLNVNLSCRIMDVFLSEGMEF-IFKVALAL 311
Cdd:pfam00566  90 TPDFPGLKRDLYVFEELLKKKLPKLYKHLKELGLDPDLFASQWFLTLFAREFPLSTVLRIWDYFFLEGEKFvLFRVALAI 169

                  ....*....
gi 260310440  312 LLTGKDTLL 320
Cdd:pfam00566 170 LKRFREELL 178
COG5210 COG5210
GTPase-activating protein [General function prediction only];
109-328 2.07e-42

GTPase-activating protein [General function prediction only];


Pssm-ID: 227535 [Multi-domain]  Cd Length: 496  Bit Score: 161.51  E-value: 2.07e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 109 VSELVRRGIPHHFRAIVWQQLSGASDGDKKQ----------YAEYIKATSACEKVIRRDIARTYPEVEFFKEKDGPGQEA 178
Cdd:COG5210  205 LRELIRKGIPNELRGDVWEFLLGIGFDLDKNpglyerllnlHREAKIPTQEIISQIEKDLSRTFPDNSLFQTEISIRAEN 284
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 179 LFNVIKAYSLHDREVGYCQGSGFIVGLLLMQMPEEE-AFAVLVQIMQQHRMRHMFKPSMSELGLCMYQLENLVQEQIPDM 257
Cdd:COG5210  285 LRRVLKAYSLYNPEVGYVQGMNFLAAPLLLVLESEEqAFWCLVKLLKNYGLPGYFLKNLSGLHRDLKVLDDLVEELDPEL 364
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 260310440 258 HIHFQQQGFQTTMYASSWFLTLYTTTLNVNLSCRIMDVFLSEGMEFIFKVALALLLTGKDTLLCLDMEAML 328
Cdd:COG5210  365 YEHLLREGVVLLMFAFRWFLTLFVREFPLEYALRIWDCLFLEGSSMLFQLALAILKLLRDKLLKLDSDELL 435
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
358-755 2.77e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 76.90  E-value: 2.77e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 358 KRMKKMEKE------YQDLKKKEQEEMAELRRLRRENC-----LLKQRNELLEAESAELADRLVRGQVSRAEEEETSYAI 426
Cdd:COG1196  200 RQLEPLERQaekaerYRELKEELKELEAELLLLKLRELeaeleELEAELEELEAELEELEAELAELEAELEELRLELEEL 279
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 427 QTELMQLRRSYLEVSHQLENANEEVRGLSLRLQENNNSRQSSIDELCMKEEALKQRDEMVSCLLEELVKVRQGLAESEDQ 506
Cdd:COG1196  280 ELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAE 359
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 507 IRNLKAKVEELEEDKktlrettpdnsvAHLQDELIASKLREAEASLSLKDLKQRVQELSSQWQRQLAENQRSESERTTNA 586
Cdd:COG1196  360 LAEAEEALLEAEAEL------------AEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELE 427
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 587 vdstpkklltnffdsskssEHTQKLEEELMTTRIREMETLTELKELRLKVMELETQVQVSTNQLRRQDEEHKKLKEELEM 666
Cdd:COG1196  428 -------------------EALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAE 488
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 667 AVTREKDMSNKAREQQHRYSDLESRMKdelmnvKIKFTEQSQTVAELKQEISRLETKNSEMLAEGELRANLDDSDKVRDL 746
Cdd:COG1196  489 AAARLLLLLEAEADYEGFLEGVKAALL------LAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAA 562

                 ....*....
gi 260310440 747 QDRLADMKA 755
Cdd:COG1196  563 IEYLKAAKA 571
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
358-665 4.78e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 66.62  E-value: 4.78e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   358 KRMKKMEKEYQDLKkkeqeemAELRRLRREncLLKQRNELLEAESAELADRLVRGQVSRAEEEETSYAIQTELMQLRRSY 437
Cdd:TIGR02168  206 ERQAEKAERYKELK-------AELRELELA--LLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEV 276
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   438 LEVS-------HQLENANEEVRGLSLRLQENNNSRQSSIDELCMKEEALKQRDEMVSCLLEELVKVRQGLAESEDQIRNL 510
Cdd:TIGR02168  277 SELEeeieelqKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESL 356
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   511 KAKVEELEEDKKTLRettpdNSVAHLQDELIASKLREAEASLSLKDLKQRVQELSSQWQRQLAENQRSESERTTNAvdst 590
Cdd:TIGR02168  357 EAELEELEAELEELE-----SRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELL---- 427
                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 260310440   591 PKKLLTNFFDSSKSSEHTQKLEEELMTTRIREMETLTELKELRLKVMELETQVQVSTNQLRRQDEEHKKLKEELE 665
Cdd:TIGR02168  428 KKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLE 502
PTZ00121 PTZ00121
MAEBL; Provisional
358-737 4.27e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 60.54  E-value: 4.27e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  358 KRMKKMEKEYQDLKKKEQEEMAELRRLRRENCLLKQRNELLEAESAELADRLVRGQVSRAEEEETSYAIQTELMQLRRsy 437
Cdd:PTZ00121 1476 KKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKK-- 1553
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  438 levSHQLENANEEVRGLSLRLQENNNSRQSSIDELCMKEEalKQRDEMVSCLLEELVKVRQGLAESEDQIRNLKAKVEEL 517
Cdd:PTZ00121 1554 ---AEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAE--EARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKA 1628
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  518 EEDKKTLRETTPDNSvahlQDELIASKLREAEASLSLK--DLKQRVQElssqwQRQLAENQRSESERTTNAVDSTPKKLl 595
Cdd:PTZ00121 1629 EEEKKKVEQLKKKEA----EEKKKAEELKKAEEENKIKaaEEAKKAEE-----DKKKAEEAKKAEEDEKKAAEALKKEA- 1698
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  596 tnffDSSKSSEHTQKLEEElmttRIREMETLTELKELRlkvmeletqvQVSTNQLRRQDEEHKKLKEELEMAVTREKDMS 675
Cdd:PTZ00121 1699 ----EEAKKAEELKKKEAE----EKKKAEELKKAEEEN----------KIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIA 1760
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 260310440  676 NKAREQQHRysdLESRMKDELMNVKIKFTEQSQTVAELKQEISRLETKNSEMLAEGELRANL 737
Cdd:PTZ00121 1761 HLKKEEEKK---AEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNL 1819
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
359-700 7.17e-09

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 59.60  E-value: 7.17e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   359 RMKKMEKEYQDLKKKEQEEMAELRRLRRENCllkqRNELLEAESAElaDRLVRGQVSRAEEEETSYAIQTELMQLRRSYL 438
Cdd:pfam02463  166 RLKRKKKEALKKLIEETENLAELIIDLEELK----LQELKLKEQAK--KALEYYQLKEKLELEEEYLLYLDYLKLNEERI 239
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   439 EVSHQLENANEEVRGLSLRLQENNNS---RQSSIDELCMKEEALKQRDEMVSCLLEELVKVRQGLAESEDQIRNLKAKVE 515
Cdd:pfam02463  240 DLLQELLRDEQEEIESSKQEIEKEEEklaQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKES 319
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   516 ELEEDKKTLRETTPDNSVAHLQDELIASKLREAEASLSLKDLKQRvQELSSQWQRQLAENQRSESERTTNAVDSTPKKLL 595
Cdd:pfam02463  320 EKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKL-QEKLEQLEEELLAKKKLESERLSSAAKLKEEELE 398
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   596 TNFFDSSKSSEHTQKLEEELMTTRIREMETLTELKELRLKVMELETQVQVSTNQLRRQDEEHKKLKEELEMAVTREKDMS 675
Cdd:pfam02463  399 LKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQ 478
                          330       340
                   ....*....|....*....|....*
gi 260310440   676 NKAREQQHRysDLESRMKDELMNVK 700
Cdd:pfam02463  479 LVKLQEQLE--LLLSRQKLEERSQK 501
 
Name Accession Description Interval E-value
TBC smart00164
Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs; Widespread domain present in Gyp6 and ...
113-320 8.86e-72

Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs; Widespread domain present in Gyp6 and Gyp7, thereby giving rise to the notion that it performs a GTP-activator activity on Rab-like GTPases.


Pssm-ID: 214540 [Multi-domain]  Cd Length: 216  Bit Score: 233.74  E-value: 8.86e-72
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   113 VRRGIPHHFRAIVWQQLSGASD----GDKKQYAEYIKATSACEKV----IRRDIARTYPEVEFFKEKDGPGQEALFNVIK 184
Cdd:smart00164   1 VRKGVPPSLRGVVWKLLLNAQPmdtsADKDLYSRLLKETAPDDKSivhqIEKDLRRTFPEHSFFQDKEGPGQESLRRVLK 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   185 AYSLHDREVGYCQGSGFIVGLLLMQMP-EEEAFAVLVQIMQQHRMRhMFKPSMSELGLCMYQLENLVQEQIPDMHIHFQQ 263
Cdd:smart00164  81 AYALYNPEVGYCQGMNFLAAPLLLVMEdEEDAFWCLVKLMERYGPN-FYLPDMSGLQLDLLQLDRLVKEYDPDLYKHLKD 159
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 260310440   264 QGFQTTMYASSWFLTLYTTTLNVNLSCRIMDVFLSEGMEFIFKVALALLLTGKDTLL 320
Cdd:smart00164 160 LGITPSLYALRWFLTLFARELPLEIVLRIWDVLFAEGSDFLFRVALALLKLHRDVLL 216
RabGAP-TBC pfam00566
Rab-GTPase-TBC domain; Identification of a TBC domain in GYP6_YEAST and GYP7_YEAST, which are ...
154-320 3.32e-53

Rab-GTPase-TBC domain; Identification of a TBC domain in GYP6_YEAST and GYP7_YEAST, which are GTPase activator proteins of yeast Ypt6 and Ypt7, implies that these domains are GTPase activator proteins of Rab-like small GTPases.


Pssm-ID: 459855  Cd Length: 178  Bit Score: 182.07  E-value: 3.32e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  154 IRRDIARTYPEVEFFKekDGPGQEALFNVIKAYSLHDREVGYCQGSGFIVGLLLMQ-MPEEEAFAVLVQIMQQHRMRHMF 232
Cdd:pfam00566  12 IEKDVPRTFPHSFFFD--NGPGQNSLRRILKAYSIYNPDVGYCQGMNFIAAPLLLVyLDEEDAFWCFVSLLENYLLRDFY 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  233 KPSMSELGLCMYQLENLVQEQIPDMHIHFQQQGFQTTMYASSWFLTLYTTTLNVNLSCRIMDVFLSEGMEF-IFKVALAL 311
Cdd:pfam00566  90 TPDFPGLKRDLYVFEELLKKKLPKLYKHLKELGLDPDLFASQWFLTLFAREFPLSTVLRIWDYFFLEGEKFvLFRVALAI 169

                  ....*....
gi 260310440  312 LLTGKDTLL 320
Cdd:pfam00566 170 LKRFREELL 178
COG5210 COG5210
GTPase-activating protein [General function prediction only];
109-328 2.07e-42

GTPase-activating protein [General function prediction only];


Pssm-ID: 227535 [Multi-domain]  Cd Length: 496  Bit Score: 161.51  E-value: 2.07e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 109 VSELVRRGIPHHFRAIVWQQLSGASDGDKKQ----------YAEYIKATSACEKVIRRDIARTYPEVEFFKEKDGPGQEA 178
Cdd:COG5210  205 LRELIRKGIPNELRGDVWEFLLGIGFDLDKNpglyerllnlHREAKIPTQEIISQIEKDLSRTFPDNSLFQTEISIRAEN 284
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 179 LFNVIKAYSLHDREVGYCQGSGFIVGLLLMQMPEEE-AFAVLVQIMQQHRMRHMFKPSMSELGLCMYQLENLVQEQIPDM 257
Cdd:COG5210  285 LRRVLKAYSLYNPEVGYVQGMNFLAAPLLLVLESEEqAFWCLVKLLKNYGLPGYFLKNLSGLHRDLKVLDDLVEELDPEL 364
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 260310440 258 HIHFQQQGFQTTMYASSWFLTLYTTTLNVNLSCRIMDVFLSEGMEFIFKVALALLLTGKDTLLCLDMEAML 328
Cdd:COG5210  365 YEHLLREGVVLLMFAFRWFLTLFVREFPLEYALRIWDCLFLEGSSMLFQLALAILKLLRDKLLKLDSDELL 435
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
358-755 2.77e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 76.90  E-value: 2.77e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 358 KRMKKMEKE------YQDLKKKEQEEMAELRRLRRENC-----LLKQRNELLEAESAELADRLVRGQVSRAEEEETSYAI 426
Cdd:COG1196  200 RQLEPLERQaekaerYRELKEELKELEAELLLLKLRELeaeleELEAELEELEAELEELEAELAELEAELEELRLELEEL 279
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 427 QTELMQLRRSYLEVSHQLENANEEVRGLSLRLQENNNSRQSSIDELCMKEEALKQRDEMVSCLLEELVKVRQGLAESEDQ 506
Cdd:COG1196  280 ELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAE 359
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 507 IRNLKAKVEELEEDKktlrettpdnsvAHLQDELIASKLREAEASLSLKDLKQRVQELSSQWQRQLAENQRSESERTTNA 586
Cdd:COG1196  360 LAEAEEALLEAEAEL------------AEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELE 427
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 587 vdstpkklltnffdsskssEHTQKLEEELMTTRIREMETLTELKELRLKVMELETQVQVSTNQLRRQDEEHKKLKEELEM 666
Cdd:COG1196  428 -------------------EALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAE 488
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 667 AVTREKDMSNKAREQQHRYSDLESRMKdelmnvKIKFTEQSQTVAELKQEISRLETKNSEMLAEGELRANLDDSDKVRDL 746
Cdd:COG1196  489 AAARLLLLLEAEADYEGFLEGVKAALL------LAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAA 562

                 ....*....
gi 260310440 747 QDRLADMKA 755
Cdd:COG1196  563 IEYLKAAKA 571
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
358-665 4.78e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 66.62  E-value: 4.78e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   358 KRMKKMEKEYQDLKkkeqeemAELRRLRREncLLKQRNELLEAESAELADRLVRGQVSRAEEEETSYAIQTELMQLRRSY 437
Cdd:TIGR02168  206 ERQAEKAERYKELK-------AELRELELA--LLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEV 276
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   438 LEVS-------HQLENANEEVRGLSLRLQENNNSRQSSIDELCMKEEALKQRDEMVSCLLEELVKVRQGLAESEDQIRNL 510
Cdd:TIGR02168  277 SELEeeieelqKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESL 356
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   511 KAKVEELEEDKKTLRettpdNSVAHLQDELIASKLREAEASLSLKDLKQRVQELSSQWQRQLAENQRSESERTTNAvdst 590
Cdd:TIGR02168  357 EAELEELEAELEELE-----SRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELL---- 427
                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 260310440   591 PKKLLTNFFDSSKSSEHTQKLEEELMTTRIREMETLTELKELRLKVMELETQVQVSTNQLRRQDEEHKKLKEELE 665
Cdd:TIGR02168  428 KKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLE 502
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
435-753 6.64e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 66.24  E-value: 6.64e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   435 RSYLEVSHQLENANEEVRGLSLRLQENNNSRQSSIDELCMKEEALKQRDEMVS----CLLEELVKVRQGLAESEDQIRNL 510
Cdd:TIGR02169  670 RSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEkeieQLEQEEEKLKERLEELEEDLSSL 749
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   511 KAKVEELEEDKKTLRETTPDNsvahlqdELIASKLREAEASLSLKDLKQRVQELSSQWQRQlaENQRSESERTTNAVDST 590
Cdd:TIGR02169  750 EQEIENVKSELKELEARIEEL-------EEDLHKLEEALNDLEARLSHSRIPEIQAELSKL--EEEVSRIEARLREIEQK 820
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   591 PKKLLTNFFDSSKSSEHTQKL-------------EEELMTTRIREMETltELKELRLKVMELEtqvqvstnqlrrqdEEH 657
Cdd:TIGR02169  821 LNRLTLEKEYLEKEIQELQEQridlkeqiksiekEIENLNGKKEELEE--ELEELEAALRDLE--------------SRL 884
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   658 KKLKEELEmavtrekDMSNKAREQQHRYSDLESRMKDELMNVKikftEQSQTVAELKQEISRLETKNSEMLAEGELRANL 737
Cdd:TIGR02169  885 GDLKKERD-------ELEAQLRELERKIEELEAQIEKKRKRLS----ELKAKLEALEEELSEIEDPKGEDEEIPEEELSL 953
                          330
                   ....*....|....*..
gi 260310440   738 DDSDKVRD-LQDRLADM 753
Cdd:TIGR02169  954 EDVQAELQrVEEEIRAL 970
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
379-719 7.90e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 65.85  E-value: 7.90e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   379 AELRRLRRENCLLKQRNELLEAESAELADRLVRGQVSRAEEEETSYAIQTELMQLRRSYLEVSHQLENANEEVRGLSLRL 458
Cdd:TIGR02168  677 REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKEL 756
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   459 QENNNSRQSSIDELCMKEEALKQrdemvscLLEELVKVRQGLAESEDQIRNLKAKVEELEEDKKTLRE--TTPDNSVAHL 536
Cdd:TIGR02168  757 TELEAEIEELEERLEEAEEELAE-------AEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEeaANLRERLESL 829
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   537 QDELIASKLREAEASLSLKDLKQRVQELSSQWQRQLAENQRSESERttnavdstpkKLLTNFFDSSKSSEHTQKLEEELM 616
Cdd:TIGR02168  830 ERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESEL----------EALLNERASLEEALALLRSELEEL 899
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   617 TTRIREMET-----LTELKELRLKVMELETQVQVSTNQLRRQDEehkKLKEE----LEMAVTREKDMSNKAREQQHRYSD 687
Cdd:TIGR02168  900 SEELRELESkrselRRELEELREKLAQLELRLEGLEVRIDNLQE---RLSEEysltLEEAEALENKIEDDEEEARRRLKR 976
                          330       340       350
                   ....*....|....*....|....*....|..
gi 260310440   688 LEsRMKDELMNVKIKFTEQSQTVAELKQEISR 719
Cdd:TIGR02168  977 LE-NKIKELGPVNLAAIEEYEELKERYDFLTA 1007
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
363-642 1.48e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 61.61  E-value: 1.48e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   363 MEKEYQDLKKKEQEEMAELRRLRRENCLLKQRNELLEAESAELADRLVRGQVSRAEEEETSYAIQTELMQLRRSYLEVSH 442
Cdd:TIGR02168  731 LRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRA 810
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   443 QLENANEEVRGLSLRLQENNNSRQSSIDELCMKEEALKQRDEMVSCLLEELVKVRQGLAESEDQIRNLKAKVEELEEDKK 522
Cdd:TIGR02168  811 ELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALA 890
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   523 TLRETTPDNSVAHLQDELIASKLREA--EASLSLKDLKQRVQELSSQWQrQLAENQRSESERTTNAVDSTPKKLLtnfFD 600
Cdd:TIGR02168  891 LLRSELEELSEELRELESKRSELRREleELREKLAQLELRLEGLEVRID-NLQERLSEEYSLTLEEAEALENKIE---DD 966
                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....
gi 260310440   601 SSKSSEHTQKLEEELmtTRIRE--METLTELKELRLKVMELETQ 642
Cdd:TIGR02168  967 EEEARRRLKRLENKI--KELGPvnLAAIEEYEELKERYDFLTAQ 1008
PTZ00121 PTZ00121
MAEBL; Provisional
358-737 4.27e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 60.54  E-value: 4.27e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  358 KRMKKMEKEYQDLKKKEQEEMAELRRLRRENCLLKQRNELLEAESAELADRLVRGQVSRAEEEETSYAIQTELMQLRRsy 437
Cdd:PTZ00121 1476 KKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKK-- 1553
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  438 levSHQLENANEEVRGLSLRLQENNNSRQSSIDELCMKEEalKQRDEMVSCLLEELVKVRQGLAESEDQIRNLKAKVEEL 517
Cdd:PTZ00121 1554 ---AEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAE--EARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKA 1628
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  518 EEDKKTLRETTPDNSvahlQDELIASKLREAEASLSLK--DLKQRVQElssqwQRQLAENQRSESERTTNAVDSTPKKLl 595
Cdd:PTZ00121 1629 EEEKKKVEQLKKKEA----EEKKKAEELKKAEEENKIKaaEEAKKAEE-----DKKKAEEAKKAEEDEKKAAEALKKEA- 1698
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  596 tnffDSSKSSEHTQKLEEElmttRIREMETLTELKELRlkvmeletqvQVSTNQLRRQDEEHKKLKEELEMAVTREKDMS 675
Cdd:PTZ00121 1699 ----EEAKKAEELKKKEAE----EKKKAEELKKAEEEN----------KIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIA 1760
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 260310440  676 NKAREQQHRysdLESRMKDELMNVKIKFTEQSQTVAELKQEISRLETKNSEMLAEGELRANL 737
Cdd:PTZ00121 1761 HLKKEEEKK---AEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNL 1819
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
359-700 7.17e-09

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 59.60  E-value: 7.17e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   359 RMKKMEKEYQDLKKKEQEEMAELRRLRRENCllkqRNELLEAESAElaDRLVRGQVSRAEEEETSYAIQTELMQLRRSYL 438
Cdd:pfam02463  166 RLKRKKKEALKKLIEETENLAELIIDLEELK----LQELKLKEQAK--KALEYYQLKEKLELEEEYLLYLDYLKLNEERI 239
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   439 EVSHQLENANEEVRGLSLRLQENNNS---RQSSIDELCMKEEALKQRDEMVSCLLEELVKVRQGLAESEDQIRNLKAKVE 515
Cdd:pfam02463  240 DLLQELLRDEQEEIESSKQEIEKEEEklaQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKES 319
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   516 ELEEDKKTLRETTPDNSVAHLQDELIASKLREAEASLSLKDLKQRvQELSSQWQRQLAENQRSESERTTNAVDSTPKKLL 595
Cdd:pfam02463  320 EKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKL-QEKLEQLEEELLAKKKLESERLSSAAKLKEEELE 398
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   596 TNFFDSSKSSEHTQKLEEELMTTRIREMETLTELKELRLKVMELETQVQVSTNQLRRQDEEHKKLKEELEMAVTREKDMS 675
Cdd:pfam02463  399 LKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQ 478
                          330       340
                   ....*....|....*....|....*
gi 260310440   676 NKAREQQHRysDLESRMKDELMNVK 700
Cdd:pfam02463  479 LVKLQEQLE--LLLSRQKLEERSQK 501
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
338-744 1.24e-08

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 58.54  E-value: 1.24e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 338 RVEADVEGFFNLAYSIKLNTKRMKKMEKEYQDLKKKEQEemaelrrLRRENCLLKQRNELLEaESAELADRLVRgqVSRA 417
Cdd:PRK03918 311 EIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKE-------LEKRLEELEERHELYE-EAKAKKEELER--LKKR 380
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 418 EEEETSYAIQTELMQLRRSYLEVSHQLENANEEVRGLSLRLQEnnnsRQSSIDEL---------CMKEEALKQRDEMVSC 488
Cdd:PRK03918 381 LTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKE----LKKAIEELkkakgkcpvCGRELTEEHRKELLEE 456
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 489 LLEELVKVRQGLAESEDQIRNLKAKVEELEEDKKTLRETTPDNSVA----HLQDELIASKLREAEA-SLSLKDLKQRVQE 563
Cdd:PRK03918 457 YTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAeqlkELEEKLKKYNLEELEKkAEEYEKLKEKLIK 536
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 564 LSSQWQRQLAENQR-----SESERTTNAVDSTPKKLltnffdssksSEHTQKLEEELMTTRIREMETLTELKELRLKVME 638
Cdd:PRK03918 537 LKGEIKSLKKELEKleelkKKLAELEKKLDELEEEL----------AELLKELEELGFESVEELEERLKELEPFYNEYLE 606
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 639 LETQVQvstnQLRRQDEEHKKLKEELEMAVTREKDMSNKAREQQHRYSDLESRM-KDELMNVKIKFTEQSQTVAELKQEI 717
Cdd:PRK03918 607 LKDAEK----ELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYsEEEYEELREEYLELSRELAGLRAEL 682
                        410       420
                 ....*....|....*....|....*...
gi 260310440 718 SRLETKNSEMLAEGE-LRANLDDSDKVR 744
Cdd:PRK03918 683 EELEKRREEIKKTLEkLKEELEEREKAK 710
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
353-694 2.36e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 57.76  E-value: 2.36e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   353 IKLNTKRMKKMEKEYQDLKK------KEQEEM--------AELRRLRRENCLLKQRNELLEAESAELADRLVRGQVSRAE 418
Cdd:TIGR02168  679 IEELEEKIEELEEKIAELEKalaelrKELEELeeeleqlrKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTE 758
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   419 EEETSYAIQTELMQLRRSYLEVSHQLENANEEVRGLSLRLQENNnsrqSSIDELcmkEEALKQRDEMVSCLLEELVKVRQ 498
Cdd:TIGR02168  759 LEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALR----EALDEL---RAELTLLNEEAANLRERLESLER 831
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   499 GLAESEDQIRNLKAKVEELEEDkktlrettpdnsVAHLQDELIASKLREAEASLSLKDLKQRVQelSSQWQRQLAENQRS 578
Cdd:TIGR02168  832 RIAATERRLEDLEEQIEELSED------------IESLAAEIEELEELIEELESELEALLNERA--SLEEALALLRSELE 897
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   579 ESERTTNAVDSTPKKLLTnffDSSKSSEHTQKLEEELMTTRIREMETLTELKEL-RLKVMELETQVQVSTNQLRRQDEEH 657
Cdd:TIGR02168  898 ELSEELRELESKRSELRR---ELEELREKLAQLELRLEGLEVRIDNLQERLSEEySLTLEEAEALENKIEDDEEEARRRL 974
                          330       340       350       360
                   ....*....|....*....|....*....|....*....|...
gi 260310440   658 KKLKEELE------MAVTREkdmsnkAREQQHRYSDLESRMKD 694
Cdd:TIGR02168  975 KRLENKIKelgpvnLAAIEE------YEELKERYDFLTAQKED 1011
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
379-757 2.91e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 57.39  E-value: 2.91e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   379 AELRRLRRENCLLKQRNELLEAESAELADRLVRGQVSRAEEEEtsyaiqtelmqlrrsYLEVSHQLENAneEVRGLSLRL 458
Cdd:TIGR02169  170 RKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAER---------------YQALLKEKREY--EGYELLKEK 232
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   459 QENNNSRQSSIDELCMKEEALKQRDEMVSCLLEELVKVRQGLAESEDQIRNLKAkvEELEEDKKTLRETTPDnsVAHLQD 538
Cdd:TIGR02169  233 EALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGE--EEQLRVKEKIGELEAE--IASLER 308
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   539 ELIASKLReaeaslsLKDLKQRVQELSSQWQRQLAEnqrseserttnavdstpkklltnffdsskssehTQKLEEELMTT 618
Cdd:TIGR02169  309 SIAEKERE-------LEDAEERLAKLEAEIDKLLAE---------------------------------IEELEREIEEE 348
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   619 RIREMETLTELKELRLKVMELETQVQVSTNQLRRQDEEHKKLKEELEMaVTREKDMSNKAR-----EQQHRYSDLEsRMK 693
Cdd:TIGR02169  349 RKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEK-LKREINELKRELdrlqeELQRLSEELA-DLN 426
                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 260310440   694 DELMNVKIKFTEQSQTVAELKQEISRLETKNSEMLA--EGELRANLDDSDKVRDLQDRLADMKAEY 757
Cdd:TIGR02169  427 AAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAAdlSKYEQELYDLKEEYDRVEKELSKLQREL 492
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
491-751 4.33e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 55.93  E-value: 4.33e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 491 EELVKVRQGLAESEDQIRNLKAKVEELEEDKKTLrettpDNSVAHLQDELIASKLREAEASLSLKDLKQRVQELssqwQR 570
Cdd:COG4942   27 AELEQLQQEIAELEKELAALKKEEKALLKQLAAL-----ERRIAALARRIRALEQELAALEAELAELEKEIAEL----RA 97
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 571 QLAENQRSESERTTNAVDSTPKKLLTNFFDSSKSSEHtqkleeelmttrIREMETLTELKELRLKVMEletqvqvstnQL 650
Cdd:COG4942   98 ELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDA------------VRRLQYLKYLAPARREQAE----------EL 155
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 651 RRQDEEHKKLKEELEMAVTREKDMSNKAREQQHRYSDLESRMKDELMNVKIKFTEQSQTVAELKQEISRLETKNSEMLAE 730
Cdd:COG4942  156 RADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235
                        250       260
                 ....*....|....*....|.
gi 260310440 731 GELRANLDDSDKVRDLQDRLA 751
Cdd:COG4942  236 AAAAAERTPAAGFAALKGKLP 256
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
358-735 5.08e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 56.87  E-value: 5.08e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 358 KRMKKMEKEYQDLKKKEQEEMAELRRLRRENCLLKQRNELLEAESAELADRLVRGQVSRAEEEETSYAIQTELMQLRRSY 437
Cdd:COG1196  414 ERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARL 493
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 438 LEVSHQLENANEEVRGLSLRLQENNNSRQSSIDELCMKEEALKQRDEMVSCLLEELVKVRQGLAESEDQIRNLKAK---- 513
Cdd:COG1196  494 LLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAkagr 573
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 514 VEELEEDKKTLRETTPDNSVAHLQDE---LIASKLREAEASLSLKDL----KQRVQELSSQWQRQLAENQRSESERTTNA 586
Cdd:COG1196  574 ATFLPLDKIRARAALAAALARGAIGAavdLVASDLREADARYYVLGDtllgRTLVAARLEAALRRAVTLAGRLREVTLEG 653
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 587 VDSTPKKLLTNFFDSSKSSEHTQKLEEELmttRIREMETLTELKELRLKVMELETQVQVSTNQLRRQDEEHKKLKEELEM 666
Cdd:COG1196  654 EGGSAGGSLTGGSRRELLAALLEAEAELE---ELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQL 730
                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 260310440 667 AVTREKdmsnkAREQQHRYSDLESRMKDELMNVKIKFTEQSQTVAELKQEISRLETKNseMLAEGELRA 735
Cdd:COG1196  731 EAEREE-----LLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALGPVN--LLAIEEYEE 792
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
356-577 6.97e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 56.10  E-value: 6.97e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 356 NTKRMKKMEKEYQDLKKKEQEEMAELRRLRRENCLLKQRNELLEAESAELADRLVRGQVSRAEEEETSYAIQTELMQLRR 435
Cdd:COG1196  314 LEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALR 393
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 436 SYLEVSHQLENANEEVRGLSLRLQENNNSRQSSIDELcmkEEALKQRDEmvscLLEELVKVRQGLAESEDQIRNLKAKVE 515
Cdd:COG1196  394 AAAELAAQLEELEEAEEALLERLERLEEELEELEEAL---AELEEEEEE----EEEALEEAAEEEAELEEEEEALLELLA 466
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 260310440 516 ELEEDKKTLREttpdnsvahLQDELIASKLREAEASLSLKDLKQRVQELSSQWQRQLAENQR 577
Cdd:COG1196  467 ELLEEAALLEA---------ALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGL 519
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
358-594 8.99e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 55.16  E-value: 8.99e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 358 KRMKKMEKEYQDLKKKEQEEMAELRRLRRENCLLKQRNELLEAESAELADRLVRGQVSRAEEEETSYAIQTELMQL---- 433
Cdd:COG4942   34 QEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELlral 113
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 434 ----RRSYLEVSHQLENANEEVRGLSLrLQENNNSRQSSIDELCMKEEALKQrdemvscLLEELVKVRQGLAESEDQIRN 509
Cdd:COG4942  114 yrlgRQPPLALLLSPEDFLDAVRRLQY-LKYLAPARREQAEELRADLAELAA-------LRAELEAERAELEALLAELEE 185
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 510 LKAKVEELEEDKKTLRETtpdnsvahlqdelIASKLREAEAslSLKDLKQRVQELSSQWQRQLAENQRSESERTTNAVDS 589
Cdd:COG4942  186 ERAALEALKAERQKLLAR-------------LEKELAELAA--ELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAA 250

                 ....*
gi 260310440 590 TPKKL 594
Cdd:COG4942  251 LKGKL 255
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
357-566 9.06e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 55.83  E-value: 9.06e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   357 TKRMKKMEKEYQDLKKKEQEEMAELRRLRRENCLLKQRNELLEAESAELADRLVRGQVSRAEEEETSYAIQTELMQLRRS 436
Cdd:TIGR02168  294 ANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESR 373
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   437 YLEVSHQLENANEEVRGLSLRLQENNNSRQSSIDELCMKEEALKQRDEMVSCLLEELV-----KVRQGLAESEDQIRNLK 511
Cdd:TIGR02168  374 LEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEeaelkELQAELEELEEELEELQ 453
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 260310440   512 AKVEELEEDKKTLREttpdnSVAHLQDELIASKLREAEASLSLKDLKQRVQELSS 566
Cdd:TIGR02168  454 EELERLEEALEELRE-----ELEEAEQALDAAERELAQLQARLDSLERLQENLEG 503
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
364-757 1.08e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 55.43  E-value: 1.08e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 364 EKEYQDLKKKEQEEMAELRRLRRENCLLKQRNELLEAESAELADRlvRGQVSRAEEEetsyaIQTELMQLRRSYLEVSHQ 443
Cdd:PRK02224 271 EREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEAR--REELEDRDEE-----LRDRLEECRVAAQAHNEE 343
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 444 LENANEEVRGLSLRLQENNNSRQSSIDELCMKEEALKQRDEMVSCLLEELVKVRQGLAESEDQIRNLKAKVEELEEDKKT 523
Cdd:PRK02224 344 AESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDE 423
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 524 LRE---------TTPDNSVAHLQDELIASK-------LREAEASLSLKDLKQRVQELssqwqrqlaENQRSESERTTNAV 587
Cdd:PRK02224 424 LREreaeleatlRTARERVEEAEALLEAGKcpecgqpVEGSPHVETIEEDRERVEEL---------EAELEDLEEEVEEV 494
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 588 DstpkKLLTNFFDSSKSSEHTQKLEE--ELMTTRIREMETLTELKELRLKvmeletqvqvstnQLRRQDEEHKKLKEELE 665
Cdd:PRK02224 495 E----ERLERAEDLVEAEDRIERLEErrEDLEELIAERRETIEEKRERAE-------------ELRERAAELEAEAEEKR 557
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 666 MAVTREKDMSNKAREQQHRYSDLESRMKDELMNVKiKFTEQSQTVAELKQEISRLETKNSEMLAEGELRanlddSDKVRD 745
Cdd:PRK02224 558 EAAAEAEEEAEEAREEVAELNSKLAELKERIESLE-RIRTLLAAIADAEDEIERLREKREALAELNDER-----RERLAE 631
                        410
                 ....*....|..
gi 260310440 746 LQDRLADMKAEY 757
Cdd:PRK02224 632 KRERKRELEAEF 643
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
391-577 1.53e-07

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 55.02  E-value: 1.53e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 391 LKQRNELLEAESAELADRL--VRGQVSRAEEEETSYAIQTELMQLRRSYLEVSHQLENANEEVRGLSLRLQENNNSRQSS 468
Cdd:COG3206  166 LELRREEARKALEFLEEQLpeLRKELEEAEAALEEFRQKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAAL 245
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 469 IDELCMKEEALKQ--RDEMVSCLLEELVKVRQGLAE-----SED--QIRNLKAKVEELEEDKKTLRETTpdnsVAHLQDE 539
Cdd:COG3206  246 RAQLGSGPDALPEllQSPVIQQLRAQLAELEAELAElsaryTPNhpDVIALRAQIAALRAQLQQEAQRI----LASLEAE 321
                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 260310440 540 LIASKLREAEASLSLKDLKQRVQELSSQwQRQLAENQR 577
Cdd:COG3206  322 LEALQAREASLQAQLAQLEARLAELPEL-EAELRRLER 358
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
359-532 1.64e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 55.07  E-value: 1.64e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   359 RMKKMEKEYQDLKKKEQEEMAELRRLRRENCLLKQRNELLEAESAELADRLVRGQVSRAEEEETSYAIQTELMQLRRSYL 438
Cdd:TIGR02169  337 EIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQ 416
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   439 EVSHQLENANEEVRGLSLRLQENNNSRQSSIDELCMKEEALKQRDEMVSCLLEELVKVRQGLAESEDQIRNLKAKVEELE 518
Cdd:TIGR02169  417 RLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAE 496
                          170
                   ....*....|....
gi 260310440   519 EDKKTLRETTPDNS 532
Cdd:TIGR02169  497 AQARASEERVRGGR 510
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
357-582 1.86e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 54.94  E-value: 1.86e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 357 TKRMKKMEKEYQDLKKKEQEEMAELRRLRRENCLLKQRNELLEAESAELADRLVRGQVSRAEEEETSYAIQTELMQLRRS 436
Cdd:COG1196  280 ELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAE 359
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 437 YLEVSHQLENANEEVRGLSLRLQENNNSRQSSIDELCMKEEALKQrdemvscLLEELVKVRQGLAESEDQIRNLKAKVEE 516
Cdd:COG1196  360 LAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEE-------LEEAEEALLERLERLEEELEELEEALAE 432
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 260310440 517 LEEDKKTLRETtpdnsvahlQDELIASKLREAEASLSLKDLKQRVQELSSQWQRQLAENQRSESER 582
Cdd:COG1196  433 LEEEEEEEEEA---------LEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEA 489
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
358-756 1.97e-07

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 54.68  E-value: 1.97e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 358 KRMKKMEKEYQDLKKKEQEEMAELRRLRRENCLLKQRNELLEaesaELADRLVRGQVSRAEEEETSYAIQTELMQLRRSY 437
Cdd:PRK03918 193 ELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELE----ELKEEIEELEKELESLEGSKRKLEEKIRELEERI 268
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 438 LEVSHQLENANEEVRglslrlqennnsrqsSIDELCMKEEALKQRDEMVSCLLEELVKVRQGLAESEDQIRNLKAKVEEL 517
Cdd:PRK03918 269 EELKKEIEELEEKVK---------------ELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKEL 333
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 518 EEDKKTLRETtpdnsvahlqdeliasKLREAEASLSLKDLKQRVQELssQWQRQLAENQRSESERTTNavdSTPKKLLTN 597
Cdd:PRK03918 334 EEKEERLEEL----------------KKKLKELEKRLEELEERHELY--EEAKAKKEELERLKKRLTG---LTPEKLEKE 392
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 598 FFDSSKSSEHTQKLEEELmTTRIREMEtlTELKELRLKVMELETQVQVSTNQLRRQDEEHKKlkeELEMAVTRE-KDMSN 676
Cdd:PRK03918 393 LEELEKAKEEIEEEISKI-TARIGELK--KEIKELKKAIEELKKAKGKCPVCGRELTEEHRK---ELLEEYTAElKRIEK 466
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 677 KAREQQHRYSDLESRMK--DELMNVKIKFTEQSQTVAELKQEISRLETKNSEMLAEgelranldDSDKVRDLQDRLADMK 754
Cdd:PRK03918 467 ELKEIEEKERKLRKELRelEKVLKKESELIKLKELAEQLKELEEKLKKYNLEELEK--------KAEEYEKLKEKLIKLK 538

                 ..
gi 260310440 755 AE 756
Cdd:PRK03918 539 GE 540
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
358-721 1.08e-06

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 52.05  E-value: 1.08e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  358 KRMKKMEKEYQDLKKKEQEEMAelrrlrREnclLKQRNELLEAESAELADrlvrgqvsrAEEEETSYAIQTELMQLRRSY 437
Cdd:pfam17380 288 QQQEKFEKMEQERLRQEKEEKA------RE---VERRRKLEEAEKARQAE---------MDRQAAIYAEQERMAMERERE 349
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  438 LEVSHQLEnaneevrglslRLQENNNSRQssiDELCMKEEALKQRDEMVSCLLEELVKVRQGLAESEdqirnlKAKVEEL 517
Cdd:pfam17380 350 LERIRQEE-----------RKRELERIRQ---EEIAMEISRMRELERLQMERQQKNERVRQELEAAR------KVKILEE 409
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  518 EEDKKTLRETTPDNSVAHLQDELIASKLREAEASLSLKDLKQRVQELSSQWQRQLAENQRSESERTTNAVDSTPKklltn 597
Cdd:pfam17380 410 ERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKR----- 484
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  598 ffDSSKSSEHTQKLEEELMTTRIREMETLTELKELRLKVMElETQVQVSTNQLRRQDEEHKKLKEELEmavtREKDMSNK 677
Cdd:pfam17380 485 --DRKRAEEQRRKILEKELEERKQAMIEEERKRKLLEKEME-ERQKAIYEEERRREAEEERRKQQEME----ERRRIQEQ 557
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....
gi 260310440  678 AREQQHRYSDLESRMKDELMNVKIKFTEQSQTVAELKQEISRLE 721
Cdd:pfam17380 558 MRKATEERSRLEAMEREREMMRQIVESEKARAEYEATTPITTIK 601
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
355-583 2.05e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 51.61  E-value: 2.05e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   355 LNTKRMKKMEKEYQDLKKKEQEEMAELRRLRRENCLLKQRNELLEAESAELadrlvrgQVSRAEEEETSYAIQTELMQLR 434
Cdd:TIGR02169  277 LNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKL-------EAEIDKLLAEIEELEREIEEER 349
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   435 RSYLEVSHQLENANEEVRGLSLRLQENNNSRQSSIDELCMKEEALKQRDEMVSCLLEELVKVRQGLAESEDQIRNLKAKV 514
Cdd:TIGR02169  350 KRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAI 429
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 260310440   515 EELEEDKKTLRETTPDNSVAHLQDELIASKLRE--AEASLSLKDLKQRVQELS---SQWQRQL--AENQRSESERT 583
Cdd:TIGR02169  430 AGIEAKINELEEEKEDKALEIKKQEWKLEQLAAdlSKYEQELYDLKEEYDRVEkelSKLQRELaeAEAQARASEER 505
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
354-726 2.30e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 51.51  E-value: 2.30e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   354 KLNTKRMKKMEKEYQDLKKKEQEEMAELRRLRRENCLLKQRNELLEAESAELADRLVRGQV-SRAEEEETSYAIQTELMQ 432
Cdd:pfam02463  644 KESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKeQREKEELKKLKLEAEELL 723
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   433 LRRSYLEVSHQLENANEEVRGLSLRLQENNNSRQSSIDELCMKEEALKQRDEMVSCLLEELVKvrqglAESEDQIRNLKA 512
Cdd:pfam02463  724 ADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKL-----KVEEEKEEKLKA 798
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   513 KVEELEEDKKTLRETtpdnsvAHLQDELIASKLREAEASLSLKDLKQRVQELSSQWQRQLAENQRSESERTTNAVDSTPK 592
Cdd:pfam02463  799 QEEELRALEEELKEE------AELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQEL 872
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   593 KLLTNFFDSSKSSEHTQKLEEELMTTRIREMETLTELKELRLKVMELETQVQVSTNQLRRQDEEHKKLKEELEMavtrEK 672
Cdd:pfam02463  873 LLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEAD----EK 948
                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....
gi 260310440   673 DMSNKAREQQHRYSDLESRMKDELMNVKIKFTEQSQTVAELKQEISRLETKNSE 726
Cdd:pfam02463  949 EKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEE 1002
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
494-757 2.61e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 51.21  E-value: 2.61e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   494 VKVRQGLAESEDQIRNLKAKVEELEED-------KKTLRETTPD--NSVAHLQDELIASKLREAEASLSLKDLKQRVQEL 564
Cdd:TIGR02168  666 AKTNSSILERRREIEELEEKIEELEEKiaelekaLAELRKELEEleEELEQLRKELEELSRQISALRKDLARLEAEVEQL 745
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   565 SSQWQRQLAENQRSESERTtnavdstpkklltnffdsskssehtqKLEEELMTTRIREMETLTELKELRLKVMELETQVQ 644
Cdd:TIGR02168  746 EERIAQLSKELTELEAEIE--------------------------ELEERLEEAEEELAEAEAEIEELEAQIEQLKEELK 799
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   645 VSTNQLRRQDEEHKKLKEELEMAVTREKDMSNKAREQQHRYSDLESR---MKDELMNVKIKFTEQSQTVAELKQEISRL- 720
Cdd:TIGR02168  800 ALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQieeLSEDIESLAAEIEELEELIEELESELEALl 879
                          250       260       270
                   ....*....|....*....|....*....|....*...
gi 260310440   721 ETKNSEMLAEGELRANLDD-SDKVRDLQDRLADMKAEY 757
Cdd:TIGR02168  880 NERASLEEALALLRSELEElSEELRELESKRSELRREL 917
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
362-754 2.92e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 50.89  E-value: 2.92e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   362 KMEKEYQDLKKKEQEEMAELRRLRRENCLLKQRNELL---EAESAELADRLVRGQVSRAEE----EETSYAIQTELM-QL 433
Cdd:pfam15921  367 QFSQESGNLDDQLQKLLADLHKREKELSLEKEQNKRLwdrDTGNSITIDHLRRELDDRNMEvqrlEALLKAMKSECQgQM 446
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   434 RRSYLEVSHQLENAnEEVRGLSLRLQENNNSRQSSIDELCMKEEALKQRDEMVSCLLEELVKVRQGLAESEDQIRNLKAK 513
Cdd:pfam15921  447 ERQMAAIQGKNESL-EKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSR 525
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   514 VEELEEDKKTLRetTPDNSVAHLQDELIASKLREAEASLSLKDLKQRVQ---ELSSQWQRQ----LAENQRSESERTTNA 586
Cdd:pfam15921  526 VDLKLQELQHLK--NEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIEnmtQLVGQHGRTagamQVEKAQLEKEINDRR 603
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   587 VDSTPKKLLTNFFDSSKSSEHTQKLEEELMTTRIREM--ETLTELKELRLKVMELETQVQVSTNQLRRQDEEHKKLK--- 661
Cdd:pfam15921  604 LELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAgsERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKrnf 683
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   662 ----EELEMAVTREK-DMSNKAREQQHRYSDLES----------------------RMKDELMNVKIKFTEQSQTVA--- 711
Cdd:pfam15921  684 rnksEEMETTTNKLKmQLKSAQSELEQTRNTLKSmegsdghamkvamgmqkqitakRGQIDALQSKIQFLEEAMTNAnke 763
                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|...
gi 260310440   712 ---------ELKQEISRLETKNSEMLAEGE-LRAnlddsdKVRDLQDRLADMK 754
Cdd:pfam15921  764 khflkeeknKLSQELSTVATEKNKMAGELEvLRS------QERRLKEKVANME 810
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
357-756 4.66e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 50.42  E-value: 4.66e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 357 TKRMKKMEKEYQDLKKKEQEEMAELRRLRRENCLLKQRNELLEAESAELADRLVRGQVSRAEEEETSYAIQTELMQLRRS 436
Cdd:PRK02224 320 EDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRER 399
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 437 YLEVSHQLENA---NEEVRGLSLRLQENNNSRQSSIDEL------------------CMKE-------EALKQRDEMVSC 488
Cdd:PRK02224 400 FGDAPVDLGNAedfLEELREERDELREREAELEATLRTArerveeaealleagkcpeCGQPvegsphvETIEEDRERVEE 479
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 489 LLEElvkvrqgLAESEDQIRNLKAKVEELEEDKKTLRETTPDNSVAHLQDELIASKLREAEA-SLSLKDLKQRVQELSS- 566
Cdd:PRK02224 480 LEAE-------LEDLEEEVEEVEERLERAEDLVEAEDRIERLEERREDLEELIAERRETIEEkRERAEELRERAAELEAe 552
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 567 -QWQRQLAENQRSESERTTNAVDSTPKKLLTNffdssksSEHTQKLE--EELMTTRIREMETLTELKELRLKVMELETQv 643
Cdd:PRK02224 553 aEEKREAAAEAEEEAEEAREEVAELNSKLAEL-------KERIESLEriRTLLAAIADAEDEIERLREKREALAELNDE- 624
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 644 qvSTNQLRRQDEEHKKLKEELEMAVTREkdmsnkAREQQHRYSDLESRMKDELMNVKIKFTEQSQTVAELKQEISRLETK 723
Cdd:PRK02224 625 --RRERLAEKRERKRELEAEFDEARIEE------AREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELEEL 696
                        410       420       430
                 ....*....|....*....|....*....|....
gi 260310440 724 NSEMLAEGELRANLDD-SDKVRDLQDRLADMKAE 756
Cdd:PRK02224 697 RERREALENRVEALEAlYDEAEELESMYGDLRAE 730
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
362-665 5.44e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 50.06  E-value: 5.44e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 362 KMEKEYQDLKKKEQEEMAELRRLRRENCLLKQRNE-----LLEAESAELADRLVRGQVSRAEEEETSYAIQTELMQLRRS 436
Cdd:PRK03918 388 KLEKELEELEKAKEEIEEEISKITARIGELKKEIKelkkaIEELKKAKGKCPVCGRELTEEHRKELLEEYTAELKRIEKE 467
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 437 YLEVSHQLENANEEVRGL-SLRLQENNNSRQSSI-DELCMKEEALKQRD-EMVSCLLEELVKVRQGLAESEDQIRNLKAK 513
Cdd:PRK03918 468 LKEIEEKERKLRKELRELeKVLKKESELIKLKELaEQLKELEEKLKKYNlEELEKKAEEYEKLKEKLIKLKGEIKSLKKE 547
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 514 VEELEEDKKTLRETtpDNSVAHLQDEL--IASKLREAEASlSLKDLKQRVQELSSQWQRQL-AENQRSESERTTNAVDST 590
Cdd:PRK03918 548 LEKLEELKKKLAEL--EKKLDELEEELaeLLKELEELGFE-SVEELEERLKELEPFYNEYLeLKDAEKELEREEKELKKL 624
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 591 PKKLLTNFFDSSKSSEHTQKL------------EEELMTTRIREMETLTELKELRLKVMELETQVQV---STNQLRRQDE 655
Cdd:PRK03918 625 EEELDKAFEELAETEKRLEELrkeleelekkysEEEYEELREEYLELSRELAGLRAELEELEKRREEikkTLEKLKEELE 704
                        330
                 ....*....|
gi 260310440 656 EHKKLKEELE 665
Cdd:PRK03918 705 EREKAKKELE 714
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
354-756 6.61e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 49.77  E-value: 6.61e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 354 KLNTKRMKKMEKEYQDLKKKEQEEMAELRRLRRenclLKQRNELLEAESAELADRLvrgqvSRAEEEETSYAIQTELMQL 433
Cdd:COG4717   67 ELNLKELKELEEELKEAEEKEEEYAELQEELEE----LEEELEELEAELEELREEL-----EKLEKLLQLLPLYQELEAL 137
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 434 RRSYLEVSHQLENANEEVRGLSlRLQENNNSRQSSIDEL------CMKEEALKQRDEMVScLLEELVKVRQGLAESEDQI 507
Cdd:COG4717  138 EAELAELPERLEELEERLEELR-ELEEELEELEAELAELqeeleeLLEQLSLATEEELQD-LAEELEELQQRLAELEEEL 215
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 508 RNLKAKVEELEEDKKTLRETTPDNSVAHLQDELIASKLREAE------ASLSLKDLKQRVQEL------------SSQWQ 569
Cdd:COG4717  216 EEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAAllallgLGGSLLSLILTIAGVlflvlgllallfLLLAR 295
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 570 RQLAENQRSESERTTNAVDSTPKKLLTNFFDSskssehtQKLEEELMTTRIRE-METLTELKELRLKVMELETQVQVSTN 648
Cdd:COG4717  296 EKASLGKEAEELQALPALEELEEEELEELLAA-------LGLPPDLSPEELLElLDRIEELQELLREAEELEEELQLEEL 368
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 649 QLRRQ---DEEHKKLKEELEMAVTREKDMSNKAREQQHRYSDLESRMKDELMNVKIKFTEQ-SQTVAELKQEISRLETKN 724
Cdd:COG4717  369 EQEIAallAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEElEEELEELEEELEELEEEL 448
                        410       420       430
                 ....*....|....*....|....*....|....*.
gi 260310440 725 SEMLAE-GELRA---NLDDSDKVRDLQDRLADMKAE 756
Cdd:COG4717  449 EELREElAELEAeleQLEEDGELAELLQELEELKAE 484
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
401-754 8.05e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 49.68  E-value: 8.05e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 401 ESAELADRLVRgQVSRAEEEETSY----AIQTELMQLRRSYLEVSHQLENANEEVRGLSLRLQEnnnsRQSSIDELCMKE 476
Cdd:PRK03918 142 ESDESREKVVR-QILGLDDYENAYknlgEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEE----VLREINEISSEL 216
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 477 EALKQRDEMVSCLLEELVKVRQGLAESEDQIRNLKAKVEELEEDKKTLREttpdnsvahlqdeliasklREAEASLSLKD 556
Cdd:PRK03918 217 PELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEE-------------------RIEELKKEIEE 277
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 557 LKQRVQELSSQWQRQLAENQRSESERTTNAVDSTPKKLLTNFfdSSKSSEHTQKLEE-ELMTTRIREMEtlTELKELRLK 635
Cdd:PRK03918 278 LEEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRL--EEEINGIEERIKElEEKEERLEELK--KKLKELEKR 353
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 636 VMELET---------QVQVSTNQL--RRQDEEHKKLKEELEMAVTREKDMSNKAREQQHRYSDLESRMKD------ELMN 698
Cdd:PRK03918 354 LEELEErhelyeeakAKKEELERLkkRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKElkkaieELKK 433
                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 260310440 699 VKIK-------FTEQ--SQTVAELKQEISRLETKNSEML-AEGELRANLDDSDKVRDLQDRLADMK 754
Cdd:PRK03918 434 AKGKcpvcgreLTEEhrKELLEEYTAELKRIEKELKEIEeKERKLRKELRELEKVLKKESELIKLK 499
mukB PRK04863
chromosome partition protein MukB;
364-729 1.65e-05

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 48.80  E-value: 1.65e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  364 EKEYQDLKKKEQEEMAELRRLRRENCLLKQRNELLEAESAELADRLVRGQVSRAEEEetsyaiqtelmqlrrsylevshQ 443
Cdd:PRK04863  292 RRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDHLNLVQTALRQQE----------------------K 349
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  444 LENANEEVRGLSLRLQENNNSRQSSIDELCMKEEALKQRDEMVSCLLEELVKVRQGLAESEDQIRNLKAKVEELEEDKK- 522
Cdd:PRK04863  350 IERYQADLEELEERLEEQNEVVEEADEQQEENEARAEAAEEEVDELKSQLADYQQALDVQQTRAIQYQQAVQALERAKQl 429
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  523 -TLRETTPDNsVAHLQDELIAsklREAEASLSLKDLKQRVqelssqwqrQLAENQRSESERTTNAVDStpkklLTNFFDS 601
Cdd:PRK04863  430 cGLPDLTADN-AEDWLEEFQA---KEQEATEELLSLEQKL---------SVAQAAHSQFEQAYQLVRK-----IAGEVSR 491
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  602 SKSSEHTQKLEEELMTTRIRemetLTELKELRLKVMELETQVQVSTNQLRRQDEEHKKLKEELEmavtREKDMSNKAREQ 681
Cdd:PRK04863  492 SEAWDVARELLRRLREQRHL----AEQLQQLRMRLSELEQRLRQQQRAERLLAEFCKRLGKNLD----DEDELEQLQEEL 563
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*...
gi 260310440  682 QHRYSDLEsrmkDELMNVKIKFTEQSQTVAELKQEISRLETKNSEMLA 729
Cdd:PRK04863  564 EARLESLS----ESVSEARERRMALRQQLEQLQARIQRLAARAPAWLA 607
CCDC22 pfam05667
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ...
466-675 2.84e-05

Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.


Pssm-ID: 461708 [Multi-domain]  Cd Length: 600  Bit Score: 47.71  E-value: 2.84e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  466 QSSIDELCMKEEALKqrdemvscllEELVKVRQGLAESEDQIRNLKAKVEELEEDKKTLRET-----TPDNSVAHLQDEL 540
Cdd:pfam05667 341 QEQLEDLESSIQELE----------KEIKKLESSIKQVEEELEELKEQNEELEKQYKVKKKTldllpDAEENIAKLQALV 410
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  541 IASKlreaeaslslkdlkQRVQELSSQW---QRQLAENQRSESERTTNavdstpkklltnffdssKSSEHTQKLEeelmt 617
Cdd:pfam05667 411 DASA--------------QRLVELAGQWekhRVPLIEEYRALKEAKSN-----------------KEDESQRKLE----- 454
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 260310440  618 triremetltELKELRlkvmeleTQVQVSTNQLRRQDEEHKKLKEELEmavTREKDMS 675
Cdd:pfam05667 455 ----------EIKELR-------EKIKEVAEEAKQKEELYKQLVAEYE---RLPKDVS 492
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
365-552 3.26e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.60  E-value: 3.26e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  365 KEYQDLKKKEQEEMAELRRLRRENclLKQRNELLEAESAELADRLVR--GQVSRAEEEETsyAIQTELMQLRRSYLEVSH 442
Cdd:COG4913   262 ERYAAARERLAELEYLRAALRLWF--AQRRLELLEAELEELRAELARleAELERLEARLD--ALREELDELEAQIRGNGG 337
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  443 Q-LENANEEVRGLSLRLQENNNSRQ--------------SSIDELcmkEEALKQRDEMVSCLLEELVKVRQGLAESEDQI 507
Cdd:COG4913   338 DrLEQLEREIERLERELEERERRRArleallaalglplpASAEEF---AALRAEAAALLEALEEELEALEEALAEAEAAL 414
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 260310440  508 RNLKAKVEELEEDKKTLReTTPDNSVAHLQD--ELIASKLREAEASL 552
Cdd:COG4913   415 RDLRRELRELEAEIASLE-RRKSNIPARLLAlrDALAEALGLDEAEL 460
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
466-756 3.37e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 47.34  E-value: 3.37e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 466 QSSIDELCMKEEALKQRDEMVSCLLEELVKVRQGLAESEDQIRNLKAKVEELEEDKKTLRETTPD--NSVAHLQDElIAS 543
Cdd:PRK02224 219 DEEIERYEEQREQARETRDEADEVLEEHEERREELETLEAEIEDLRETIAETEREREELAEEVRDlrERLEELEEE-RDD 297
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 544 KLREAE-ASLSLKDLKQRVQELSSQWQ--RQLAENQRSESERTTNAVDSTPKKLLTNFFDSSKSSEHTQKLEEELMTTRI 620
Cdd:PRK02224 298 LLAEAGlDDADAEAVEARREELEDRDEelRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEARE 377
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 621 REMETLTELKELRLKVMELETQVQVSTNQLRRQDEEHKKLKEELEMAVTREKDMSNKAREQQHRYSDLE----------- 689
Cdd:PRK02224 378 AVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEalleagkcpec 457
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 260310440 690 ------SRMKDELMNVKIKFTEQSQTVAELKQEISRLETK--NSEMLAEGELRANlDDSDKVRDLQDRLADMKAE 756
Cdd:PRK02224 458 gqpvegSPHVETIEEDRERVEELEAELEDLEEEVEEVEERleRAEDLVEAEDRIE-RLEERREDLEELIAERRET 531
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
357-564 3.52e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 47.37  E-value: 3.52e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   357 TKRMKKMEKEYQDLKKKEQEEMAELRRLRRENCLLKQRNELLEAESAELADRLvrgqvsrAEEEETSYAIQTELMQLRRS 436
Cdd:TIGR02169  715 SRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARI-------EELEEDLHKLEEALNDLEAR 787
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   437 YL-----EVSHQLENANEEVRGLSLRLQE-------------------------------NNNSRQSSIDELCMKEEALK 480
Cdd:TIGR02169  788 LShsripEIQAELSKLEEEVSRIEARLREieqklnrltlekeylekeiqelqeqridlkeQIKSIEKEIENLNGKKEELE 867
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   481 QRDEMVSCLLEELVKVRQGLA----ESEDQIRNLKAKVEELEEDKKTLRETTPDNSVA--HLQDEL------IASKLREA 548
Cdd:TIGR02169  868 EELEELEAALRDLESRLGDLKkerdELEAQLRELERKIEELEAQIEKKRKRLSELKAKleALEEELseiedpKGEDEEIP 947
                          250
                   ....*....|....*.
gi 260310440   549 EASLSLKDLKQRVQEL 564
Cdd:TIGR02169  948 EEELSLEDVQAELQRV 963
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
439-726 3.73e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 47.32  E-value: 3.73e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  439 EVSHQLENANEEVRGLSLRLQENNNSrqssIDELcmkEEALKQRDEMVSCLLEELVKVRQGLAESEDQIRNLKAKVEELE 518
Cdd:TIGR04523 311 ELKSELKNQEKKLEEIQNQISQNNKI----ISQL---NEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYK 383
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  519 EDKKTLRettpdNSVAHLQDELIASKLREAEASLSLKDLKQRVQELSSQWQRQLAENQRSESERTTNAVDSTPKKLLTNF 598
Cdd:TIGR04523 384 QEIKNLE-----SQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKN 458
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  599 FDSSKSSEHTQ--KLEEELMTTRiREMETLTelKELRLKVMELETQvqvsTNQLRRQDEEHKKLKEELEMAVTREKDMSN 676
Cdd:TIGR04523 459 LDNTRESLETQlkVLSRSINKIK-QNLEQKQ--KELKSKEKELKKL----NEEKKELEEKVKDLTKKISSLKEKIEKLES 531
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 260310440  677 KAREQQHRYSDLES---RMKDELMNVKIK--FTEQSQTVAELKQEISRLETKNSE 726
Cdd:TIGR04523 532 EKKEKESKISDLEDelnKDDFELKKENLEkeIDEKNKEIEELKQTQKSLKKKQEE 586
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
363-633 6.93e-05

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 46.04  E-value: 6.93e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  363 MEKEYQDLKKKEQEEMAELRRLRRENCLLKQRNELLEAESAELADRLVRGQVSRAEEEETSYAIQTELMQlrrsylevsh 442
Cdd:pfam07888 113 LSEEKDALLAQRAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEEEAERKQLQAKLQQ---------- 182
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  443 qlenANEEVRGLSLRLQENNNSR----------QSSIDELCMKEEALKQRDEMVSCLLEELVKVRQGLAESEDQIRNLKA 512
Cdd:pfam07888 183 ----TEEELRSLSKEFQELRNSLaqrdtqvlqlQDTITTLTQKLTTAHRKEAENEALLEELRSLQERLNASERKVEGLGE 258
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  513 KVEELEEDKKtlrettpdnsvaHLQDELIASKLREAEASLSLKDLKQRVQELSSQWQ------RQLAENQRSESERTTNA 586
Cdd:pfam07888 259 ELSSMAAQRD------------RTQAELHQARLQAAQLTLQLADASLALREGRARWAqeretlQQSAEADKDRIEKLSAE 326
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 260310440  587 VDSTPKKLltnffdsSKSSEHTQKLEEELM----TTRIREMETLTELKELR 633
Cdd:pfam07888 327 LQRLEERL-------QEERMEREKLEVELGrekdCNRVQLSESRRELQELK 370
PTZ00121 PTZ00121
MAEBL; Provisional
358-754 7.79e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 46.67  E-value: 7.79e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  358 KRMKKMEKEYQDLKKKEQEEMAELRRLRRENCLLKQRNELLEAESAELADRLVRGQVSRAEEEETSYAIQTELMQLRRSY 437
Cdd:PTZ00121 1308 KKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKA 1387
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  438 LEV--SHQLENANEEVRGLSLRLQENNNSRQSSiDELCMKEEALKQRDEMVScLLEELVKVRQGL--AESEDQIRNLKAK 513
Cdd:PTZ00121 1388 EEKkkADEAKKKAEEDKKKADELKKAAAAKKKA-DEAKKKAEEKKKADEAKK-KAEEAKKADEAKkkAEEAKKAEEAKKK 1465
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  514 VEE---LEEDKKTLRETTPDNSVAHLQDELI--ASKLREA-EASLSLKDLKQRVQELSSQWQRQLAENQRSESERTTNAV 587
Cdd:PTZ00121 1466 AEEakkADEAKKKAEEAKKADEAKKKAEEAKkkADEAKKAaEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEK 1545
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  588 ---DSTPKKLLTNFFDSSKSSEHTQKlEEELMTTRIREMETLTELKELRLK-VMELETQVQVSTNQLRRQDEEHKKLKEE 663
Cdd:PTZ00121 1546 kkaDELKKAEELKKAEEKKKAEEAKK-AEEDKNMALRKAEEAKKAEEARIEeVMKLYEEEKKMKAEEAKKAEEAKIKAEE 1624
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  664 LEMAVTREKDMSNKAREQQHRYSDLESRMKDELMNvKIKFTEQSQTVAELKQEISRL-ETKNSEMLAEGELRANLDDSDK 742
Cdd:PTZ00121 1625 LKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEEN-KIKAAEEAKKAEEDKKKAEEAkKAEEDEKKAAEALKKEAEEAKK 1703
                         410
                  ....*....|..
gi 260310440  743 VRDLQDRLADMK 754
Cdd:PTZ00121 1704 AEELKKKEAEEK 1715
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
324-747 1.22e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 45.88  E-value: 1.22e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   324 MEAMLKFFQKELPGRVEADVEGFFNLAYSIKLNTKRMKKMEKEYQDLKKKEQEEMAELRRLRRE-------NCLLKQRNE 396
Cdd:pfam15921  431 LEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSertvsdlTASLQEKER 510
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   397 LLEAESAELADRLVRGQVSRAE------EEETSYAIQTELMQLRRSYLEVSHQLENANEEVRGLS-LRLQENNNSRQSSI 469
Cdd:pfam15921  511 AIEATNAEITKLRSRVDLKLQElqhlknEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTqLVGQHGRTAGAMQV 590
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   470 DELCMKEEALKQRDEmvsclLEELVKVRQglaESEDQIRNLKAKVEELEEDKKTLrettpdnsVAHLQDELIASKLREAE 549
Cdd:pfam15921  591 EKAQLEKEINDRRLE-----LQEFKILKD---KKDAKIRELEARVSDLELEKVKL--------VNAGSERLRAVKDIKQE 654
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   550 ASLSLKDLKQRVQELSSQWQ-----RQLAENQRSESERTTNAVDSTPKKLLTNFFDSSKSSEHTQKLEEELMTTRIREME 624
Cdd:pfam15921  655 RDQLLNEVKTSRNELNSLSEdyevlKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQK 734
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   625 TLT----ELKELRLKVMELETQVQVSTNQLRRQDEEHKKLKEELEMAVTREKDMSNKAREQQHRysdlESRMKDELMNVK 700
Cdd:pfam15921  735 QITakrgQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQ----ERRLKEKVANME 810
                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*..
gi 260310440   701 IKFTEQSQTVAELKQEISRLETKNsemlaegeLRANLDDSDKVRDLQ 747
Cdd:pfam15921  811 VALDKASLQFAECQDIIQRQEQES--------VRLKLQHTLDVKELQ 849
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
349-722 1.34e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 45.73  E-value: 1.34e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   349 LAYSIKLNTKRMKKMEKEYQDLKKKEQEEMAELRRLRRENCLLKQRNELLEAESAELADRLVRGQVS----RAEEEETSY 424
Cdd:TIGR00618  519 DIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDipnlQNITVRLQD 598
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   425 AIQTELMQLRRSYLEVSHQLENANEEVRGLSLRLQENNNSRQSSIDELCMKEEALKQRDEMVScllEELVKVRQGLAESE 504
Cdd:TIGR00618  599 LTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVR---EHALSIRVLPKELL 675
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   505 DQIRNLKAKVEELEEDKKTLRETTPDnsvahlqdelIASKLREAEASLslKDLKQRVQELSsqwqrQLAENQRSESERTT 584
Cdd:TIGR00618  676 ASRQLALQKMQSEKEQLTYWKEMLAQ----------CQTLLRELETHI--EEYDREFNEIE-----NASSSLGSDLAARE 738
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   585 NAVDSTPKKLLTNFFDSSKSS--EHTQKLEEELMttrirEMETLTELKELRLKVMELETQVQVSTNQLRRQDEEHKKLKE 662
Cdd:TIGR00618  739 DALNQSLKELMHQARTVLKARteAHFNNNEEVTA-----ALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIP 813
                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   663 ELEMAVTREKDMSNKAREQQHRYSDLESRMKDELMNVKIKFTEQSQTVAELKQEISRLET 722
Cdd:TIGR00618  814 SDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQ 873
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
354-726 1.49e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 45.40  E-value: 1.49e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  354 KLNTKRMKKmEKEYQDLKKKEQeemaelrrlrRENCLLKQRNELlEAESAELADRLVRGQVSRAEEEETSYAIQTELMQL 433
Cdd:TIGR04523 191 KIKNKLLKL-ELLLSNLKKKIQ----------KNKSLESQISEL-KKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQL 258
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  434 RRSYLEVSHQLENANEEVRGLSLRLQENNNSrqssIDELCMKEEALKQRDE--MVSCLLEELVKVRQGLAESEDQIRNLK 511
Cdd:TIGR04523 259 KDEQNKIKKQLSEKQKELEQNNKKIKELEKQ----LNQLKSEISDLNNQKEqdWNKELKSELKNQEKKLEEIQNQISQNN 334
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  512 AKVEELEED----KKTLRETTPDNS-----VAHLQDELIASKLREAEASLSLKDLKQRVQELSSQWQRQLAENQRSESER 582
Cdd:TIGR04523 335 KIISQLNEQisqlKKELTNSESENSekqreLEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQI 414
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  583 TTNAVDstpKKLLTNFFDSSKSSEHTQKLEEELMTTRIREMETltELKELRLKVMELETQVQVSTNQLRRQDEEHKKLKE 662
Cdd:TIGR04523 415 KKLQQE---KELLEKEIERLKETIIKNNSEIKDLTNQDSVKEL--IIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQK 489
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 260310440  663 ELEMAVTREKDMSNKAREQQHRYSDLESRMKDELMNVKIKFTEQSQTVAELKQEISRLETKNSE 726
Cdd:TIGR04523 490 ELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFE 553
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
475-756 2.03e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 45.05  E-value: 2.03e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   475 KEEALKQRDEMvsclLEELVKVRQGLAESEDQIRNLKAKVEELEEDKKtlrettpdnsvahLQDELiasklREAEASLSL 554
Cdd:TIGR02168  174 RKETERKLERT----RENLDRLEDILNELERQLKSLERQAEKAERYKE-------------LKAEL-----RELELALLV 231
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   555 KDLKQRVQELSsQWQRQLAENQRSESERTTNAVdstpkklltnffdsskssehtqkleeelmttriremETLTELKELRL 634
Cdd:TIGR02168  232 LRLEELREELE-ELQEELKEAEEELEELTAELQ------------------------------------ELEEKLEELRL 274
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   635 KVMELETQVQVSTNQLRRQDEEHKKLKEELEMAVTREKDMSNKAREQQHRYSDLESR---MKDELMNVKIKFTEQSQTVA 711
Cdd:TIGR02168  275 EVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKldeLAEELAELEEKLEELKEELE 354
                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*..
gi 260310440   712 ELKQEISRLETKNSEM-LAEGELRANLDD-SDKVRDLQDRLADMKAE 756
Cdd:TIGR02168  355 SLEAELEELEAELEELeSRLEELEEQLETlRSKVAQLELQIASLNNE 401
PTZ00121 PTZ00121
MAEBL; Provisional
351-754 2.28e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 45.13  E-value: 2.28e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  351 YSIKLNTKRMKKMEKEYQDLKKKEQEEMAELRRLRRENCLLKQRNELLEAESAELADRLVRGQVSRAEEEETSYAIQTEL 430
Cdd:PTZ00121 1081 FDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKA 1160
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  431 MQLRRsyLEVSHQLENAN--------EEVR-GLSLRLQENNNSRQSS--IDELCMKEEALKQRDEMVSCLLEELVKVRQG 499
Cdd:PTZ00121 1161 EDARK--AEEARKAEDAKkaeaarkaEEVRkAEELRKAEDARKAEAArkAEEERKAEEARKAEDAKKAEAVKKAEEAKKD 1238
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  500 LAESE--DQIRNLKA--KVEELEEDKKTLRETTPDNSVAHLQDEL-------IASKLREAEASLSLKDLKQRVQEL-SSQ 567
Cdd:PTZ00121 1239 AEEAKkaEEERNNEEirKFEEARMAHFARRQAAIKAEEARKADELkkaeekkKADEAKKAEEKKKADEAKKKAEEAkKAD 1318
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  568 WQRQLAENQRSESERTTNAVDSTPKKLLTNFFDSSKSSEHTQKLEEELMTTRIREMETLTELKELRLKVMELEtqvqvST 647
Cdd:PTZ00121 1319 EAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKK-----KA 1393
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  648 NQLRRQDEEHKKLKEELEMAVTREKDMSNKAREQQHRYSDLESRMKDElmnvKIKFTEQSQTVAELKQEISRLETKNSEM 727
Cdd:PTZ00121 1394 DEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAE----EAKKADEAKKKAEEAKKAEEAKKKAEEA 1469
                         410       420
                  ....*....|....*....|....*..
gi 260310440  728 LAEGELRANLDDSDKVRDLQDRLADMK 754
Cdd:PTZ00121 1470 KKADEAKKKAEEAKKADEAKKKAEEAK 1496
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
353-541 2.84e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.98  E-value: 2.84e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 353 IKLNTKRMKKMEKEYQDLKKKEQEEMAELRRLRRENCLLKQRNE---LLEAESAELADRLVR--GQVSRaeeeetsyAIQ 427
Cdd:COG4942   78 LAALEAELAELEKEIAELRAELEAQKEELAELLRALYRLGRQPPlalLLSPEDFLDAVRRLQylKYLAP--------ARR 149
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 428 TELMQLRRSYLEVSHQLENANEEVRGLSLRLQENNNSRQSsidelcmKEEALKQRDEMVSCLLEELVKVRQGLAESEDQI 507
Cdd:COG4942  150 EQAEELRADLAELAALRAELEAERAELEALLAELEEERAA-------LEALKAERQKLLARLEKELAELAAELAELQQEA 222
                        170       180       190
                 ....*....|....*....|....*....|....
gi 260310440 508 RNLKAKVEELEEDKKTLRETTPDNSVAHLQDELI 541
Cdd:COG4942  223 EELEALIARLEAEAAAAAERTPAAGFAALKGKLP 256
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
361-748 2.86e-04

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 44.40  E-value: 2.86e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   361 KKMEKEYQDLKKKEQEEMAELRRLRRENC--------------LLKQRNELLEAESAELADRLVRGQVSRAEEEETSYAI 426
Cdd:pfam01576   99 KKMQQHIQDLEEQLDEEEAARQKLQLEKVtteakikkleedilLLEDQNSKLSKERKLLEERISEFTSNLAEEEEKAKSL 178
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   427 Q----------TELMQLRRSYLEVSHQLENANEEVRGLSLRLQENNNSRQSSIDELCMKeeaLKQRDEMVSCLLEELVKV 496
Cdd:pfam01576  179 SklknkheamiSDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQIAELRAQ---LAKKEEELQAALARLEEE 255
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   497 RQGLAESEDQIRNLKAKVEELEEDKKTLR--ETTPDNSVAHLQDELIASKlREAEASLslkDLKQRVQELSSQWQRQLAE 574
Cdd:pfam01576  256 TAQKNNALKKIRELEAQISELQEDLESERaaRNKAEKQRRDLGEELEALK-TELEDTL---DTTAAQQELRSKREQEVTE 331
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   575 NQRSESERTTNAVDSTpkklltnffdSSKSSEHTQKLEE--ELMTTRIREMETLTELKElRLKVMELETQVQVSTNQLRR 652
Cdd:pfam01576  332 LKKALEEETRSHEAQL----------QEMRQKHTQALEEltEQLEQAKRNKANLEKAKQ-ALESENAELQAELRTLQQAK 400
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   653 QDEEHKKLKEELEMAVTREKdmSNKAREQQHRYSDLESRMKDELMNVKIKFTEQSQTVAELKQEISRLETK--NSEMLAE 730
Cdd:pfam01576  401 QDSEHKRKKLEGQLQELQAR--LSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQlqDTQELLQ 478
                          410
                   ....*....|....*...
gi 260310440   731 GELRANLDDSDKVRDLQD 748
Cdd:pfam01576  479 EETRQKLNLSTRLRQLED 496
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
364-689 3.01e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 44.56  E-value: 3.01e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  364 EKEYQDLKKKEQEEMAELRRLRRENCLLKQRNELLEAESAELADRLVRGQVSRAEEEetsyaiqtelmqlrrsylevshQ 443
Cdd:COG3096   291 RRELFGARRQLAEEQYRLVEMARELEELSARESDLEQDYQAASDHLNLVQTALRQQE----------------------K 348
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  444 LENANEEVRGLSLRLQENNNSRQSSIDELCMKEEALKQRDEMVSCLLEELVKVRQGLaeSEDQIRNLKAK--VEELEEDK 521
Cdd:COG3096   349 IERYQEDLEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQAL--DVQQTRAIQYQqaVQALEKAR 426
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  522 KTLREttPDNSVAHLQDELIASKLREAEASLSLKDLKQRV---QELSSQWQRQLAENQRSESERTTNAVDSTPKKLLTNF 598
Cdd:COG3096   427 ALCGL--PDLTPENAEDYLAAFRAKEQQATEEVLELEQKLsvaDAARRQFEKAYELVCKIAGEVERSQAWQTARELLRRY 504
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  599 FDSSKSSEHTQKLEEELmttriREMETLTELKElrlKVMELETQVQVSTNQLRRQDEEHKKLKEELEmavTREKDMSNKA 678
Cdd:COG3096   505 RSQQALAQRLQQLRAQL-----AELEQRLRQQQ---NAERLLEEFCQRIGQQLDAAEELEELLAELE---AQLEELEEQA 573
                         330
                  ....*....|.
gi 260310440  679 REQQHRYSDLE 689
Cdd:COG3096   574 AEAVEQRSELR 584
COG5022 COG5022
Myosin heavy chain [General function prediction only];
506-744 3.38e-04

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 44.30  E-value: 3.38e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  506 QIRNLKAKVEEleedKKTLRETTpDNSVAHLQDELIASKLREAEASLSLKDLKQRVQELSSQWQRQLAENQRSEserTTN 585
Cdd:COG5022   818 CIIKLQKTIKR----EKKLRETE-EVEFSLKAEVLIQKFGRSLKAKKRFSLLKKETIYLQSAQRVELAERQLQE---LKI 889
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  586 AVDSTPKKLLTNFFDSSKSSEHTQKLEEELMTTRIREMETLTELKELRLKVM-----ELETQVQVSTNQLRRQDEEHKKL 660
Cdd:COG5022   890 DVKSISSLKLVNLELESEIIELKKSLSSDLIENLEFKTELIARLKKLLNNIDleegpSIEYVKLPELNKLHEVESKLKET 969
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  661 KEELEMAV---TREKDMSNKAREQQHRYSDLESRMKDELMnvkiKFTEQSQTVAELKQEISRLETKNSEMLAEGELRANL 737
Cdd:COG5022   970 SEEYEDLLkksTILVREGNKANSELKNFKKELAELSKQYG----ALQESTKQLKELPVEVAELQSASKIISSESTELSIL 1045

                  ....*..
gi 260310440  738 DDSDKVR 744
Cdd:COG5022  1046 KPLQKLK 1052
PRK11281 PRK11281
mechanosensitive channel MscK;
463-644 4.17e-04

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 44.13  E-value: 4.17e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  463 NSRQSSIDELcMKEEALKQRDEMVSCLLEELVKVRQGLAESEDQIRNLKAKVEELEEdkkTLRETTpdNSVAHLQDELiA 542
Cdd:PRK11281   39 ADVQAQLDAL-NKQKLLEAEDKLVQQDLEQTLALLDKIDRQKEETEQLKQQLAQAPA---KLRQAQ--AELEALKDDN-D 111
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  543 SKLREAEASLSLKDLKQRVQELSSQ---WQRQLAE------NQRSESERTTNAVDSTPK------KLLTNFFDSSKSSEH 607
Cdd:PRK11281  112 EETRETLSTLSLRQLESRLAQTLDQlqnAQNDLAEynsqlvSLQTQPERAQAALYANSQrlqqirNLLKGGKVGGKALRP 191
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 260310440  608 TQK--LEEEL------MTTRIREME---TLTEL-----KELRLKVMELETQVQ 644
Cdd:PRK11281  192 SQRvlLQAEQallnaqNDLQRKSLEgntQLQDLlqkqrDYLTARIQRLEHQLQ 244
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
442-722 4.50e-04

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 44.06  E-value: 4.50e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   442 HQLENANEEVRGLSLRLQENNNSRQSSIDELCMKEEALKQRDEMVSCLLEElvkVRQGLAESEDQIRNLKAKVEELeEDK 521
Cdd:pfam12128  230 IQAIAGIMKIRPEFTKLQQEFNTLESAELRLSHLHFGYKSDETLIASRQEE---RQETSAELNQLLRTLDDQWKEK-RDE 305
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   522 KTLRETTPDNSVAHLQDELiasKLREAEASLSLK-DLKQRVQELSS--QWQRQLAENQRSESERTTNAVDSTPKkllTNF 598
Cdd:pfam12128  306 LNGELSAADAAVAKDRSEL---EALEDQHGAFLDaDIETAAADQEQlpSWQSELENLEERLKALTGKHQDVTAK---YNR 379
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   599 FDSSKSSEHTQKLEE-ELMTTRIREmETLTELKELRLKVMELETQVQVSTN-QLRRQDEEHKKLK--------------- 661
Cdd:pfam12128  380 RRSKIKEQNNRDIAGiKDKLAKIRE-ARDRQLAVAEDDLQALESELREQLEaGKLEFNEEEYRLKsrlgelklrlnqata 458
                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 260310440   662 -EELEMAVTREKDMSNKAREQQHRYSDLESRMKDELMNVKIKFTEQS-------QTVAELKQEISRLET 722
Cdd:pfam12128  459 tPELLLQLENFDERIERAREEQEAANAEVERLQSELRQARKRRDQASealrqasRRLEERQSALDELEL 527
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
475-756 4.62e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 43.77  E-value: 4.62e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 475 KEEALKQRDEMvsclleelvkvRQGLAESEDQIRNLKAKVEELEEDKKTLREttpdnsVAHLQDELiasKLREAE-ASLS 553
Cdd:COG1196  174 KEEAERKLEAT-----------EENLERLEDILGELERQLEPLERQAEKAER------YRELKEEL---KELEAElLLLK 233
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 554 LKDLKQRVQELSSQwqRQLAENQRSESERTTNAVDSTPKKLLTNFFDSSKSSEHTQKLEEELMTTRIREMETLT----EL 629
Cdd:COG1196  234 LRELEAELEELEAE--LEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIArleeRR 311
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 630 KELRLKVMELETQVQVSTNQLRRQDEEHKKLKEELEMAVTREKDMSNKAREQQHRYSDLESRMKDELMNVKIKFTEQSQT 709
Cdd:COG1196  312 RELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEA 391
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*..
gi 260310440 710 VAELKQEISRLETKNSEMLAEGELRANLDDSDKVRDLQDRLADMKAE 756
Cdd:COG1196  392 LRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEE 438
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
489-733 4.71e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 43.89  E-value: 4.71e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   489 LLEELVKVRQGLAESEDQIRNLKAKVEELEEDKKTLRETTP--DNSVAHLQDELIASKLREAEASLSLKDLKQRVQELSS 566
Cdd:TIGR02168  237 LREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSelEEEIEELQKELYALANEISRLEQQKQILRERLANLER 316
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   567 QWQRQLAENQRSESERttnavdstpkklltnffdsskssehtQKLEEELMTTRIREMETLTELKELRLKVMELETQVQVS 646
Cdd:TIGR02168  317 QLEELEAQLEELESKL--------------------------DELAEELAELEEKLEELKEELESLEAELEELEAELEEL 370
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   647 TNQLRRQDEEHKKLKEEL-----EMAVTREKDMSNKAR--EQQHRYSDLESRMKDELMN-VKIKFTEQSQTVAELKQEIS 718
Cdd:TIGR02168  371 ESRLEELEEQLETLRSKVaqlelQIASLNNEIERLEARleRLEDRRERLQQEIEELLKKlEEAELKELQAELEELEEELE 450
                          250
                   ....*....|....*
gi 260310440   719 RLETKNSEMLAEGEL 733
Cdd:TIGR02168  451 ELQEELERLEEALEE 465
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
364-747 4.88e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 43.80  E-value: 4.88e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   364 EKEYQDLKKKEQEEMAELRRLRRENCLLKQRNELLEAES----------AELAD--RLVRGQVSRAEEEETSYAIQTELM 431
Cdd:TIGR00618  448 TCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETrkkavvlarlLELQEepCPLCGSCIHPNPARQDIDNPGPLT 527
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   432 QLRRSYLEVSHQLENANEEVRGLSLRLQENNNSRQSSIDELCMKEEALKQRDEMVSCLLEELVKVRQGLAESEDQirNLK 511
Cdd:TIGR00618  528 RRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEK--LSE 605
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   512 AKVEELEEDKKTLRETTPDnsvAHLQDELIASKLREAEASLSLKDLKQRVQELSSQWQRQLAENQRSESERTTNAVDSTP 591
Cdd:TIGR00618  606 AEDMLACEQHALLRKLQPE---QDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLAL 682
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   592 KKLltnffDSSKSSEHTQKLEEELMTTRIREMEtlTELKELRLKVMELETQVQVSTNQLRRQDEEHKKLKEELEmavtRE 671
Cdd:TIGR00618  683 QKM-----QSEKEQLTYWKEMLAQCQTLLRELE--THIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELM----HQ 751
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   672 KDMSNKAREQQHRYSDLESRMK----DELMNVKIKFTEQSQTVAELKQEISRLETKNSEMLAEGELRANLDDSDKVRDLQ 747
Cdd:TIGR00618  752 ARTVLKARTEAHFNNNEEVTAAlqtgAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEE 831
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
348-721 8.01e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 43.09  E-value: 8.01e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  348 NLAYSIKLNTKRMKKMEKEYQDLKKKEQEEMAELRRLRREncLLKQRNELLEAESaeladrlvrgQVSRAEEEETSYaiQ 427
Cdd:TIGR04523 107 KINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTE--IKKKEKELEKLNN----------KYNDLKKQKEEL--E 172
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  428 TELMQLRRSYLEVSHQLENANEEVRGLSLRL------QENNNSRQSSIDELcmkEEALKQRDEMVSCLLEELVKVRQGLA 501
Cdd:TIGR04523 173 NELNLLEKEKLNIQKNIDKIKNKLLKLELLLsnlkkkIQKNKSLESQISEL---KKQNNQLKDNIEKKQQEINEKTTEIS 249
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  502 ESEDQIRNLK-----------AKVEELEEDKKTLRETTpdNSVAHLQDELiaSKLREAEASLSLKDLKQRVQelSSQWQR 570
Cdd:TIGR04523 250 NTQTQLNQLKdeqnkikkqlsEKQKELEQNNKKIKELE--KQLNQLKSEI--SDLNNQKEQDWNKELKSELK--NQEKKL 323
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  571 QLAENQRSESERTTNAVDSTPKKLLTNFFDS-SKSSEHTQKLEE---ELMTTRIREMETLTELKELRLKVMELETQVQVS 646
Cdd:TIGR04523 324 EEIQNQISQNNKIISQLNEQISQLKKELTNSeSENSEKQRELEEkqnEIEKLKKENQSYKQEIKNLESQINDLESKIQNQ 403
                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 260310440  647 TNQLRRQDEEHKKLKEELEMAVTREKDMSNKAREQQHRYSDLEsrmkDELMNVKIKFTEQSQTVAELKQEISRLE 721
Cdd:TIGR04523 404 EKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLT----NQDSVKELIIKNLDNTRESLETQLKVLS 474
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
375-567 9.21e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.98  E-value: 9.21e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  375 QEEMAELRRLRRENCLLKQRNELLE------------AESAELADRLV------RGQVSRAEEEETSYAIQTELMQLRRS 436
Cdd:COG4913   231 VEHFDDLERAHEALEDAREQIELLEpirelaeryaaaRERLAELEYLRaalrlwFAQRRLELLEAELEELRAELARLEAE 310
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  437 YLEVSHQLENANEEVRGLSLRLQENNNSRqssIDELcmkEEALKQRDemvscllEELVKVRQGLAESEDQIRNLKAKVEE 516
Cdd:COG4913   311 LERLEARLDALREELDELEAQIRGNGGDR---LEQL---EREIERLE-------RELEERERRRARLEALLAALGLPLPA 377
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 260310440  517 LEEDKKTLRETTPDnSVAHLQDELIASKLREAEASLSLKDLKQRVQELSSQ 567
Cdd:COG4913   378 SAEEFAALRAEAAA-LLEALEEELEALEEALAEAEAALRDLRRELRELEAE 427
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
397-756 1.06e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 42.80  E-value: 1.06e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   397 LLEAESAELADRLVRGQVSRAEEEETSYAIQTELMQLRRSYLEVshQLE-NANEEVRGLSLRLQEN-NNSRQSSIDEL-- 472
Cdd:pfam15921   79 VLEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEM--QMErDAMADIRRRESQSQEDlRNQLQNTVHELea 156
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   473 --CMKEEALKQRDEMVscllEELVKVRQGLAESEDQIRNLKAKVEELEEDKKTLRETTpdnSVAHLQD--ELIASKLREA 548
Cdd:pfam15921  157 akCLKEDMLEDSNTQI----EQLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSM---STMHFRSlgSAISKILREL 229
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   549 EASLSLkdLKQRVQELSSQWQRQLAENQ-------RSESERTTNAVDSTPKKL--LTNFFDSSKSSEHTQKLEEELMTTR 619
Cdd:pfam15921  230 DTEISY--LKGRIFPVEDQLEALKSESQnkielllQQHQDRIEQLISEHEVEItgLTEKASSARSQANSIQSQLEIIQEQ 307
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   620 IREMETLtelkeLRLKVMELETQVQVSTNQLRRQDEEHKKLKEELEMAVTREKDMSNKAREQQHRYSDLESRMKDELMNV 699
Cdd:pfam15921  308 ARNQNSM-----YMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKL 382
                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 260310440   700 KIKFTEQSQTVAELKQEISRL---ETKNSemLAEGELRANLDDSD-KVRDLQDRLADMKAE 756
Cdd:pfam15921  383 LADLHKREKELSLEKEQNKRLwdrDTGNS--ITIDHLRRELDDRNmEVQRLEALLKAMKSE 441
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
348-755 1.50e-03

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 42.02  E-value: 1.50e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  348 NLAYSIKLNTKRMKKMEKEYQ-------DLKKKEQEEMAELRRLRRENCLLKQRnelLEAESAELaDRLVRGQVSRAEEE 420
Cdd:pfam05483 300 DIKMSLQRSMSTQKALEEDLQiatkticQLTEEKEAQMEELNKAKAAHSFVVTE---FEATTCSL-EELLRTEQQRLEKN 375
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  421 ETSYAIQTELMQLRRSYLEVSHQLENANE-------EVRGLSLRLQENNNSRQSSIDELCMKEEAL----KQRDEMVSCL 489
Cdd:pfam05483 376 EDQLKIITMELQKKSSELEEMTKFKNNKEveleelkKILAEDEKLLDEKKQFEKIAEELKGKEQELifllQAREKEIHDL 455
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  490 LEELVKVRQGLAESEDQIRNLKAkveELEEDKKTLRETTPDNSVAHLQDELIASKlrEAEASLSLKDLKQRVQELSSQWQ 569
Cdd:pfam05483 456 EIQLTAIKTSEEHYLKEVEDLKT---ELEKEKLKNIELTAHCDKLLLENKELTQE--ASDMTLELKKHQEDIINCKKQEE 530
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  570 RQLA--ENQRSESERTTNAVDSTPKKLLtnffdsSKSSEHTQKLEEELMTTRIREMETLTELKELRLkvmeletqVQVST 647
Cdd:pfam05483 531 RMLKqiENLEEKEMNLRDELESVREEFI------QKGDEVKCKLDKSEENARSIEYEVLKKEKQMKI--------LENKC 596
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  648 NQLRRQDEEHKKLKEELEMAVTREKDMSNKAREQQHRYSDLESRMKDELMNVKIKFTEQSQTvaeLKQEISRLETKNSEM 727
Cdd:pfam05483 597 NNLKKQIENKNKNIEELHQENKALKKKGSAENKQLNAYEIKVNKLELELASAKQKFEEIIDN---YQKEIEDKKISEEKL 673
                         410       420       430
                  ....*....|....*....|....*....|....
gi 260310440  728 LAEGE-LRANLDDSDKVRD-----LQDRLADMKA 755
Cdd:pfam05483 674 LEEVEkAKAIADEAVKLQKeidkrCQHKIAEMVA 707
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
443-678 1.59e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.67  E-value: 1.59e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 443 QLENANEEVRGLSLRLQENNNSRQSSIDELCMKEEALKQRDEMVSCLLEELVKVRQGLAESEDQIRNLKAKVEELEED-K 521
Cdd:COG4942   28 ELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEElA 107
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 522 KTLRETTPDNSVAHLQDELIASKLREAEASLS-LKDLKQRVQELSSQWQRQLAENQRSESERTTNavdstpkklltnffd 600
Cdd:COG4942  108 ELLRALYRLGRQPPLALLLSPEDFLDAVRRLQyLKYLAPARREQAEELRADLAELAALRAELEAE--------------- 172
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 260310440 601 sskssehtQKLEEELMTTRIREMETLTELKELRLKVM-ELETQVQVSTNQLRRQDEEHKKLKEELEMAVTREKDMSNKA 678
Cdd:COG4942  173 --------RAELEALLAELEEERAALEALKAERQKLLaRLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERT 243
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
359-730 1.75e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 42.08  E-value: 1.75e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   359 RMKKMEKEYQDLKKKEQEEMAELRRLRRENCLLKQRNELLEAESAELADRLVRGQVSRAEEEETSYAIQTELMQLRRSYL 438
Cdd:pfam01576  195 RLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQIS 274
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   439 EVSHQLEN-------ANEEVRGLSLRLQENNNSRQSSIDELCMKEEALKQRDEMVSCL---LEELVKVR----------- 497
Cdd:pfam01576  275 ELQEDLESeraarnkAEKQRRDLGEELEALKTELEDTLDTTAAQQELRSKREQEVTELkkaLEEETRSHeaqlqemrqkh 354
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   498 -QGLAESEDQIRNLKAKVEELEEDKKTLrettpDNSVAHLQDELIASKLREAEASLSLKDLKQRVQELS---SQWQRQLA 573
Cdd:pfam01576  355 tQALEELTEQLEQAKRNKANLEKAKQAL-----ESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQarlSESERQRA 429
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   574 ENQ------RSESERTTNAVDSTPKKLLTNFFDSSKSSEHTQKLEEEL---------MTTRIREMET-----LTELKELR 633
Cdd:pfam01576  430 ELAeklsklQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQELLqeetrqklnLSTRLRQLEDernslQEQLEEEE 509
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   634 LKVMELETQVQVSTNQL----RRQDEE----------HKKLKEELEMAVTREKDMSnkarEQQHRYSDLESRMKDELMNV 699
Cdd:pfam01576  510 EAKRNVERQLSTLQAQLsdmkKKLEEDagtlealeegKKRLQRELEALTQQLEEKA----AAYDKLEKTKNRLQQELDDL 585
                          410       420       430
                   ....*....|....*....|....*....|.
gi 260310440   700 KIKFTEQSQTVAELKQEisrlETKNSEMLAE 730
Cdd:pfam01576  586 LVDLDHQRQLVSNLEKK----QKKFDQMLAE 612
46 PHA02562
endonuclease subunit; Provisional
457-688 1.95e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 41.54  E-value: 1.95e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 457 RLQENNnsrqSSIDELCMKEEALKQRDEMVSCLLEELVKVrqglaeSEDQIRNLKAKVEELEEDKKTLRettpdNSVAHL 536
Cdd:PHA02562 175 KIRELN----QQIQTLDMKIDHIQQQIKTYNKNIEEQRKK------NGENIARKQNKYDELVEEAKTIK-----AEIEEL 239
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 537 QDELIASKLREAEASLSLKDLKQRVQELSSQWQRQLAENQRSESERT----TNAVDSTPKKLLTNffdSSKSSEHTQKLe 612
Cdd:PHA02562 240 TDELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQFQKVIKMYEKGGVcptcTQQISEGPDRITKI---KDKLKELQHSL- 315
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 260310440 613 EELMTTRIREMETLTELKELRLKVMELETQVQVSTNQLRRQDEEHKKLKEELEMAVTREKDMSNKAREQQHRYSDL 688
Cdd:PHA02562 316 EKLDTAIDELEEIMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQDELDKI 391
PLN00181 PLN00181
protein SPA1-RELATED; Provisional
394-597 1.95e-03

protein SPA1-RELATED; Provisional


Pssm-ID: 177776 [Multi-domain]  Cd Length: 793  Bit Score: 41.61  E-value: 1.95e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 394 RNELLEAESA-ELADRLvrgqvsraEEEEtsyaiqtelmqlrrSYLEVSHQLENANEEVrglSLRLQENNNSRQSSIDEL 472
Cdd:PLN00181 272 RENLEEREAAmELRDRI--------EEQE--------------LLLEFLFLIQQRKQEA---ADKLQDTISLLSSDIDQV 326
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 473 CMKEEALKQRDEMVSCLLEELVKVRQGLAESEDQIRNLKAKVEELEEDKKTLRETTP-DNSVAHLQDELIASKLREAEAS 551
Cdd:PLN00181 327 VKRQLVLQQKGSDVRSFLASRKRIRQGAETLAAEEENDDNSSKLDDTLESTLLESSRlMRNLKKLESVYFATRYRQIKAA 406
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 260310440 552 LSLKDLKQRVQELSSqwqrqlaENQRSeSERTTNAVDSTPKKLLTN 597
Cdd:PLN00181 407 AAAEKPLARYYSALS-------ENGRS-SEKSSMSNPAKPPDFYIN 444
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
492-696 2.24e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 40.97  E-value: 2.24e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 492 ELVKVRQGLAESEDQIRNLKAKVEELEEDKKTLREttpdnSVAHLQDELIASKLREAEASLSLKDLKQRVQELSSQWQRQ 571
Cdd:COG3883   17 QIQAKQKELSELQAELEAAQAELDALQAELEELNE-----EYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGER 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 572 LAENQRSESerTTNAVD-----STPKKLLTNFFDSSKSSEHTQKLeeelmttriremetLTELKELRLKVMELETQVQVS 646
Cdd:COG3883   92 ARALYRSGG--SVSYLDvllgsESFSDFLDRLSALSKIADADADL--------------LEELKADKAELEAKKAELEAK 155
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 260310440 647 TNQLRRQDEEHKKLKEELEMAVTREKDMSNKAREQQHRYSDLESRMKDEL 696
Cdd:COG3883  156 LAELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAEL 205
PTZ00121 PTZ00121
MAEBL; Provisional
368-756 2.29e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 41.67  E-value: 2.29e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  368 QDLKKKEQEEMAELRRlRRENclLKQRNELLEAESAELADRLVRGQVSRAEEEETSYAIQTELMQLRRSYLEV------- 440
Cdd:PTZ00121 1191 EELRKAEDARKAEAAR-KAEE--ERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEArmahfar 1267
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  441 ------------SHQLENANEEVRGLSLRLQEnnnsRQSSIDELCMKEEALKQRDEMVSCLLEELVKVRQGLAESEDQIR 508
Cdd:PTZ00121 1268 rqaaikaeearkADELKKAEEKKKADEAKKAE----EKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKK 1343
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  509 NLKAKVEELEEDKKTLRETtpdnsvahlQDELIASKLREAEASLSLKDLKQRVQElssqwqRQLAENQRSESERTTNAVD 588
Cdd:PTZ00121 1344 AAEAAKAEAEAAADEAEAA---------EEKAEAAEKKKEEAKKKADAAKKKAEE------KKKADEAKKKAEEDKKKAD 1408
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  589 STPKKLltnffDSSKSSEHTQKLEEElmttrIREMETLTELKELRLKVMELETQVQVS--TNQLRRQDEEHKKLKEELEM 666
Cdd:PTZ00121 1409 ELKKAA-----AAKKKADEAKKKAEE-----KKKADEAKKKAEEAKKADEAKKKAEEAkkAEEAKKKAEEAKKADEAKKK 1478
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  667 AVTREK--DMSNKAREQQHRYSDLESRMKDELMNVKIKFTEQSQTVAELKQEisrLETKNSEMLAEGELRANLDDSDKVR 744
Cdd:PTZ00121 1479 AEEAKKadEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKA---EEAKKADEAKKAEEKKKADELKKAE 1555
                         410
                  ....*....|..
gi 260310440  745 DLQDRLADMKAE 756
Cdd:PTZ00121 1556 ELKKAEEKKKAE 1567
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
379-737 2.54e-03

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 41.03  E-value: 2.54e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  379 AELRRLRRENCLlKQRNELLEAESAELADRlvrgQVSRAEEEETSYAIQTELMQLRRSYLEVSHQLENANEEVRGLSLRL 458
Cdd:pfam07888  29 AELLQNRLEECL-QERAELLQAQEAANRQR----EKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKY 103
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  459 QENNNSRQSSIDE---LCMKEEALKQR----DEMVSCLLEELVKVRQGLAESEDQIRNLKAKVEELEEDKKTLrETTPDN 531
Cdd:pfam07888 104 KELSASSEELSEEkdaLLAQRAAHEARirelEEDIKTLTQRVLERETELERMKERAKKAGAQRKEEEAERKQL-QAKLQQ 182
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  532 SVAHLQDelIASKLREAEASLSLKDLK-QRVQELSSQWQRQLAENQRSESErttnavDSTPKKLLTNFFDSSKSSEHT-Q 609
Cdd:pfam07888 183 TEEELRS--LSKEFQELRNSLAQRDTQvLQLQDTITTLTQKLTTAHRKEAE------NEALLEELRSLQERLNASERKvE 254
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  610 KLEEELMTTRIREMETLTELKELRLKVMELETQVQVSTNQLRRQDEEHKKLKEELEMAVTREKDMSNKAREQQHRysdLE 689
Cdd:pfam07888 255 GLGEELSSMAAQRDRTQAELHQARLQAAQLTLQLADASLALREGRARWAQERETLQQSAEADKDRIEKLSAELQR---LE 331
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*....
gi 260310440  690 SRMKDELMnvkikftEQSQTVAELKQEISRLETKNSEMLAE-GELRANL 737
Cdd:pfam07888 332 ERLQEERM-------EREKLEVELGREKDCNRVQLSESRRElQELKASL 373
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
354-730 3.27e-03

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 40.96  E-value: 3.27e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  354 KLNTKRMK-KMEKEYQDLKKKEQEEMA---ELRRLRRENC-------LLK-------QRNELLEAESAELADRLVRG--- 412
Cdd:pfam10174 281 KSHSKFMKnKIDQLKQELSKKESELLAlqtKLETLTNQNSdckqhieVLKesltakeQRAAILQTEVDALRLRLEEKesf 360
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  413 ------QVSRAEEEETSYAIQTELMQ------------LRRSYLEVSHQLENANEEVRGLSLRLQENNNSRQSSIDELCM 474
Cdd:pfam10174 361 lnkktkQLQDLTEEKSTLAGEIRDLKdmldvkerkinvLQKKIENLQEQLRDKDKQLAGLKERVKSLQTDSSNTDTALTT 440
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  475 KEEALKQRDEMVSCL-----------LEELVKVRQGLAESEDQIRNLKAKVEELEEDKKTLRETTPDNSVAHLQDEliaS 543
Cdd:pfam10174 441 LEEALSEKERIIERLkeqreredrerLEELESLKKENKDLKEKVSALQPELTEKESSLIDLKEHASSLASSGLKKD---S 517
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  544 KLREAEASlslkdLKQRVQElSSQWQRQLAENQRSESERTTNAVDSTPKKLLTNFFDSSKSSEHTQKLEEELMTTRIREM 623
Cdd:pfam10174 518 KLKSLEIA-----VEQKKEE-CSKLENQLKKAHNAEEAVRTNPEINDRIRLLEQEVARYKEESGKAQAEVERLLGILREV 591
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  624 ETLTELKELRLKVMELETQVQV------STNQLRRQDEEHKKLKEELEMAVTREKDMSNKAREQQ-HRYSDLESRMKDEL 696
Cdd:pfam10174 592 ENEKNDKDKKIAELESLTLRQMkeqnkkVANIKHGQQEMKKKGAQLLEEARRREDNLADNSQQLQlEELMGALEKTRQEL 671
                         410       420       430
                  ....*....|....*....|....*....|....
gi 260310440  697 MNVKIKFTEQSQTVAELKQEISRLETKNSEMLAE 730
Cdd:pfam10174 672 DATKARLSSTQQSLAEKDGHLTNLRAERRKQLEE 705
PRK01156 PRK01156
chromosome segregation protein; Provisional
358-726 3.52e-03

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 41.04  E-value: 3.52e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 358 KRMKKMEKEYQDLKKKEQEEMAELRRLRRENCLLKQRNELLEAESAELADRLVRGQVsraeeeeTSYAIQTELMQLRRSY 437
Cdd:PRK01156 346 SRYDDLNNQILELEGYEMDYNSYLKSIESLKKKIEEYSKNIERMSAFISEILKIQEI-------DPDAIKKELNEINVKL 418
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 438 LEVSHQLENANEEVRGLSLRLQE-NNNSRQSSIDELC----------MKEEALKQRDEMVSCLLEELVKVRQGLAESEDQ 506
Cdd:PRK01156 419 QDISSKVSSLNQRIRALRENLDElSRNMEMLNGQSVCpvcgttlgeeKSNHIINHYNEKKSRLEEKIREIEIEVKDIDEK 498
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 507 IRNLKaKVEELEEDKKTLRETTPDNSVAHLQDELIASKLREAEaslsLKDLKQRVQELSSQWQRQLAENQRSESERTTNA 586
Cdd:PRK01156 499 IVDLK-KRKEYLESEEINKSINEYNKIESARADLEDIKIKINE----LKDKHDKYEEIKNRYKSLKLEDLDSKRTSWLNA 573
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 587 ---VDSTPKKLLTNFFDSSKSS-----EHTQKLEEEL------MTTRIREMEtlTELKELRLKVMELEtQVQVSTNQLRR 652
Cdd:PRK01156 574 lavISLIDIETNRSRSNEIKKQlndleSRLQEIEIGFpddksyIDKSIREIE--NEANNLNNKYNEIQ-ENKILIEKLRG 650
                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 260310440 653 QDEEHKKLKEELEMAVTREKDMSNKAREQQHRYSDLESRMKDELMNVkikfTEQSQTVAELKQEISRLETKNSE 726
Cdd:PRK01156 651 KIDNYKKQIAEIDSIIPDLKEITSRINDIEDNLKKSRKALDDAKANR----ARLESTIEILRTRINELSDRIND 720
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
362-718 3.63e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 40.77  E-value: 3.63e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  362 KMEKEYQDLKKKEQ--EEMAELRRLRRENCLLKQRNELLEAESAELADRLVRGQVSRAEEEETSYAIQTELMQLRRSYLE 439
Cdd:TIGR04523 351 LTNSESENSEKQREleEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIER 430
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  440 VSHQLENANEEVRglslRLQENNNSRQSSIDELCMKEEALKQRDEMVSCLLE----ELVKVRQGLAESEDQIRNLKAKVE 515
Cdd:TIGR04523 431 LKETIIKNNSEIK----DLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINkikqNLEQKQKELKSKEKELKKLNEEKK 506
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  516 ELEEDKKTLREttpdnSVAHLQDELIASKLREAEASLSLKDLKQRVQELSSQWQRQLAENQRSESERTTNAVDSTPKKLL 595
Cdd:TIGR04523 507 ELEEKVKDLTK-----KISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKENLEKEIDEKNKEIEELKQTQKSLK 581
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  596 tnffdssKSSEHTQKLEEELMTtriremetltELKELRLKVMELETQVQVSTNQLRRQDEEHKKLKEELemavTREKDMS 675
Cdd:TIGR04523 582 -------KKQEEKQELIDQKEK----------EKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSII----KNIKSKK 640
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|...
gi 260310440  676 NKAREQQHrysdlesRMKDELMNVKIKFTEQSQTVAELKQEIS 718
Cdd:TIGR04523 641 NKLKQEVK-------QIKETIKEIRNKWPEIIKKIKESKTKID 676
46 PHA02562
endonuclease subunit; Provisional
538-757 4.04e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 40.38  E-value: 4.04e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 538 DELIASKLREAEASLSLKDLKQRVQELSSQWQRQLAENQRSEserttNAVDSTPKKlltNFFDSSKSSEHTQKLEEELMT 617
Cdd:PHA02562 169 DKLNKDKIRELNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKK-----NGENIARKQ---NKYDELVEEAKTIKAEIEELT 240
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 618 TRI----REMETLTE-LKELRLKVMELETQVQvstnQLRRQDEEHKK------LKEELEMAVTREKDMSNKAREQQHRYS 686
Cdd:PHA02562 241 DELlnlvMDIEDPSAaLNKLNTAAAKIKSKIE----QFQKVIKMYEKggvcptCTQQISEGPDRITKIKDKLKELQHSLE 316
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 687 DLESRMkDELMNVKIKFTEQSQTVAEL-------KQEISRLETKNSEMLAE-GELRA-NLDDSDKVRDLQDRLADMKAEY 757
Cdd:PHA02562 317 KLDTAI-DELEEIMDEFNEQSKKLLELknkistnKQSLITLVDKAKKVKAAiEELQAeFVDNAEELAKLQDELDKIVKTK 395
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
490-722 4.09e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 40.72  E-value: 4.09e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   490 LEELVKVRQGLAESEDQIRNLKAKVEELEEDKKTLRETTPD------NSVAHLQDEL--IASKLREAEASLSLKDLKQRV 561
Cdd:TIGR00618  172 LFPLDQYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCmpdtyhERKQVLEKELkhLREALQQTQQSHAYLTQKREA 251
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   562 QELSSQWQRQL---------AENQRSESERTTNAVDSTPKKLltNFFDSSKSSEHTQKLEEELMTTRIREMETLTELKEL 632
Cdd:TIGR00618  252 QEEQLKKQQLLkqlrarieeLRAQEAVLEETQERINRARKAA--PLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMK 329
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440   633 RLKVM----------ELETQVQVSTNQLRRQDEEHKKLKEELEMAVTREKDMSNKAREQQH--RYSDLESRMKDELMNVK 700
Cdd:TIGR00618  330 RAAHVkqqssieeqrRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTltQKLQSLCKELDILQREQ 409
                          250       260
                   ....*....|....*....|..
gi 260310440   701 IKFTEQSQTVAELKQEISRLET 722
Cdd:TIGR00618  410 ATIDTRTSAFRDLQGQLAHAKK 431
HEC1 COG5185
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ...
476-751 5.12e-03

Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 444066 [Multi-domain]  Cd Length: 594  Bit Score: 40.33  E-value: 5.12e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 476 EEALKQRDEMVSCLLEELVKVRQGLAES----EDQIRNLKAKVEELEEDKKTLRETTPDNSVAHLQDEL--IASKLREAE 549
Cdd:COG5185  256 EKLVEQNTDLRLEKLGENAESSKRLNENannlIKQFENTKEKIAEYTKSIDIKKATESLEEQLAAAEAEqeLEESKRETE 335
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 550 ASLslkdlkQRVQELSSQWQRQLAENQRSESERTTNAVDSTpkklltnffDSSKSSEHTQKLEEELMTTRiremetltel 629
Cdd:COG5185  336 TGI------QNLTAEIEQGQESLTENLEAIKEEIENIVGEV---------ELSKSSEELDSFKDTIESTK---------- 390
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 630 KELRLKVMELETQVQVSTNQLRR----QDEEHKKLKEELEMAVTREKDMSNKAREQQHRYSDLESRMKDELMN-----VK 700
Cdd:COG5185  391 ESLDEIPQNQRGYAQEILATLEDtlkaADRQIEELQRQIEQATSSNEEVSKLLNELISELNKVMREADEESQSrleeaYD 470
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|...
gi 260310440 701 IKFTEQSQTVAELKQEISRLETKNSEMLAEGE-LRANLDDS-DKVRDLQDRLA 751
Cdd:COG5185  471 EINRSVRSKKEDLNEELTQIESRVSTLKATLEkLRAKLERQlEGVRSKLDQVA 523
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
459-763 5.93e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 40.11  E-value: 5.93e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  459 QENNNSRQSSIDELCMKEEALKQ-RDEMVSCL-----LEELVKVRQGLAESEDQIRNLKAKVE-ELEEDKKTLRETTPDN 531
Cdd:pfam17380 281 QKAVSERQQQEKFEKMEQERLRQeKEEKAREVerrrkLEEAEKARQAEMDRQAAIYAEQERMAmERERELERIRQEERKR 360
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  532 SVAHLQDELIA---SKLREAEA-SLSLKDLKQRV-QELSSQWQRQLAENQRSESERTTNAVDSTPKKLLTNffdssKSSE 606
Cdd:pfam17380 361 ELERIRQEEIAmeiSRMRELERlQMERQQKNERVrQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEE-----ARQR 435
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  607 HTQKLEEElmttRIREMEtltelkelRLKVMELETQVQVstnQLRRQDEEHKKlKEELEMavtrEKDMSNKAREQQHRYS 686
Cdd:pfam17380 436 EVRRLEEE----RAREME--------RVRLEEQERQQQV---ERLRQQEEERK-RKKLEL----EKEKRDRKRAEEQRRK 495
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  687 DLESRMKDELMNV------------------KIKFTEQSQTVAE----LKQEISRLETKNSEMLAEGELRANLDDSDKVR 744
Cdd:pfam17380 496 ILEKELEERKQAMieeerkrkllekemeerqKAIYEEERRREAEeerrKQQEMEERRRIQEQMRKATEERSRLEAMERER 575
                         330       340
                  ....*....|....*....|....
gi 260310440  745 DLQDRLAD---MKAEYP--TPITS 763
Cdd:pfam17380 576 EMMRQIVEsekARAEYEatTPITT 599
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
483-689 6.86e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 40.00  E-value: 6.86e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 483 DEMVSCLLEELVKVRQGLAES-----EDQIRNLKAKVEELEEDKKTLRETTPDNSVAhLQDELIASKLREAEASLSlkDL 557
Cdd:COG3206  155 NALAEAYLEQNLELRREEARKaleflEEQLPELRKELEEAEAALEEFRQKNGLVDLS-EEAKLLLQQLSELESQLA--EA 231
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 558 KQRVQELSSQW---QRQLAENQRSESERTTNAVdstpkklltnffdsskssehTQKLEEELMTTRIREMETLTELKELRL 634
Cdd:COG3206  232 RAELAEAEARLaalRAQLGSGPDALPELLQSPV--------------------IQQLRAQLAELEAELAELSARYTPNHP 291
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 260310440 635 KVMELETQVQVSTNQLRRQDEE-HKKLKEELEMAVTREKDMSNKAREQQHR----------YSDLE 689
Cdd:COG3206  292 DVIALRAQIAALRAQLQQEAQRiLASLEAELEALQAREASLQAQLAQLEARlaelpeleaeLRRLE 357
HAP1_N pfam04849
HAP1 N-terminal conserved region; This family represents an N-terminal conserved region found ...
355-563 8.24e-03

HAP1 N-terminal conserved region; This family represents an N-terminal conserved region found in several huntingtin-associated protein 1 (HAP1) homologs. HAP1 binds to huntingtin in a polyglutamine repeat-length-dependent manner. However, its possible role in the pathogenesis of Huntington's disease is unclear. This family also includes a similar N-terminal conserved region from hypothetical protein products of ALS2CR3 genes found in the human juvenile amyotrophic lateral sclerosis critical region 2q33-2q34.


Pssm-ID: 461455 [Multi-domain]  Cd Length: 309  Bit Score: 39.24  E-value: 8.24e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  355 LNTKRMKKMEKEYQDLKK-----KEQEEMAEL-----RRLRRENCLLKQRNELLEAESAELADRLVRGQ----------- 413
Cdd:pfam04849  53 LCSDRVSQMTKTYNDIEAvtrllEEKERDLELaarigQSLLKQNSVLTERNEALEEQLGSAREEILQLRhelskkddllq 132
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  414 -VSRAEEEETSYAIQTELMQLRRSYLEVSH--QLENANEEVRGlslrLQENNNSRQSSIDELCMKEEALKQRDEM----- 485
Cdd:pfam04849 133 iYSNDAEESETESSCSTPLRRNESFSSLHGcvQLDALQEKLRG----LEEENLKLRSEASHLKTETDTYEEKEQQlmsdc 208
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  486 ----------VSCLLEELVKVRQGLAESEDQIRNLKAKVEELEEDKKTLRETTPDnsvahLQDELIASKLREAEASLSLK 555
Cdd:pfam04849 209 veqlseanqqMAELSEELARKMEENLRQQEEITSLLAQIVDLQHKCKELGIENEE-----LQQHLQASKEAQRQLTSELQ 283

                  ....*...
gi 260310440  556 DLKQRVQE 563
Cdd:pfam04849 284 ELQDRYAE 291
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
353-693 8.87e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 39.64  E-value: 8.87e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 353 IKLNTKRMKKMEKEYQDLKKKEQEEMAELRRLRREncLLKQRNEL--LEAESAELADRLVRGQVSRAEEEETSYAIQTEL 430
Cdd:PRK02224 344 AESLREDADDLEERAEELREEAAELESELEEAREA--VEDRREEIeeLEEEIEELRERFGDAPVDLGNAEDFLEELREER 421
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 431 MQLRRSYLEVSHQLENANEEVRGLSLRLQENNNSRQSSIDELCMKEEALKQRDEMVSCLLEELvkvrqglAESEDQIRNL 510
Cdd:PRK02224 422 DELREREAELEATLRTARERVEEAEALLEAGKCPECGQPVEGSPHVETIEEDRERVEELEAEL-------EDLEEEVEEV 494
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 511 KAKVEELEEDKKTLRETTPDNSVAHLQDELIASKLREAEA-SLSLKDLKQRVQELSS--QWQRQLAENQRSESERTTNAV 587
Cdd:PRK02224 495 EERLERAEDLVEAEDRIERLEERREDLEELIAERRETIEEkRERAEELRERAAELEAeaEEKREAAAEAEEEAEEAREEV 574
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440 588 DSTPKKL--LTNFFDS---------------------------------------SKSSEHTQKLEEELMTTRIRE---- 622
Cdd:PRK02224 575 AELNSKLaeLKERIESlerirtllaaiadaedeierlrekrealaelnderrerlAEKRERKRELEAEFDEARIEEared 654
                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 260310440 623 -------METLTE-LKELRLKVMELETQVQVSTNQLRRQDEEHKKLkEELEMAVTREKDMSNKAREQQHRYSDLESRMK 693
Cdd:PRK02224 655 keraeeyLEQVEEkLDELREERDDLQAEIGAVENELEELEELRERR-EALENRVEALEALYDEAEELESMYGDLRAELR 732
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
353-732 9.30e-03

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 39.32  E-value: 9.30e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  353 IKLNTKRMKKMEKEYQDLKKKEQEEMAELRRLRRENCLLKQRNELLEAESAELADRLVRGQVSRAEE-----------EE 421
Cdd:pfam05483 115 IEAQRKAIQELQFENEKVSLKLEEEIQENKDLIKENNATRHLCNLLKETCARSAEKTKKYEYEREETrqvymdlnnniEK 194
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  422 TSYAIQTELMQLRRSYLEVSHQLENANEEVRGLSLRLQENNNSRQSSIDELC---------------------------- 473
Cdd:pfam05483 195 MILAFEELRVQAENARLEMHFKLKEDHEKIQHLEEEYKKEINDKEKQVSLLLiqitekenkmkdltflleesrdkanqle 274
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  474 ----MKEEALKQRDEMVSCLLEELVKVRQGLAES-------EDQIRNLKAKVEELEEDKKTLRETTPDNSVAHlqdELIA 542
Cdd:pfam05483 275 ektkLQDENLKELIEKKDHLTKELEDIKMSLQRSmstqkalEEDLQIATKTICQLTEEKEAQMEELNKAKAAH---SFVV 351
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  543 SKLREAEASLS--LKDLKQRVQELSSQWQRQLAENQRSESE-----RTTNAVDSTPKKLLTNFFDSSK---SSEHTQKLE 612
Cdd:pfam05483 352 TEFEATTCSLEelLRTEQQRLEKNEDQLKIITMELQKKSSEleemtKFKNNKEVELEELKKILAEDEKlldEKKQFEKIA 431
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 260310440  613 EELMTTrirEMETLTELKELRLKVMELETQVQVSTNQLRRQDEEHKKLKEELEMAVTREKDM---SNKAREQQHRYSDLE 689
Cdd:pfam05483 432 EELKGK---EQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELtahCDKLLLENKELTQEA 508
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|...
gi 260310440  690 SRMKDELMNVKIKFTEQSQTVAELKQEISRLETKNSEMLAEGE 732
Cdd:pfam05483 509 SDMTLELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDELE 551
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH