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Conserved domains on  [gi|268055390|gb|ACY93072|]
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odorant binding protein 18a [Drosophila melanogaster]

Protein Classification

pheromone/general odorant binding protein( domain architecture ID 10653825)

pheromone/general odorant binding protein (PBP/GOBP) is an olfaction-related protein characterized by six conserved cysteines that are paired in three disulfide bridges

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PhBP smart00708
Insect pheromone/odorant binding protein domains;
26-121 8.31e-09

Insect pheromone/odorant binding protein domains;


:

Pssm-ID: 214783  Cd Length: 103  Bit Score: 49.35  E-value: 8.31e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268055390    26 AEGCLKHHNLTSAQV-QAVAPSTPVADVPvAVKCYSRCLI--QDYFGDDGKIDLQKVGKR------GSQEDHVILSQCKQ 96
Cdd:smart00708   2 REECKKELGVSEADLaDFVKFWREDYPDE-KVKCYIKCVLkkLGLMDDDGKFDAEKLLEQlkaddeMAEELEDIIEKCEK 80

                           90       100
                   ....*....|....*....|....*
gi 268055390    97 QFDgvTNLDTCDYPYLILQCYFKGK 121
Cdd:smart00708  81 KKG--TEEDPCDTAYRVAKCFKKAI 103
 
Name Accession Description Interval E-value
PhBP smart00708
Insect pheromone/odorant binding protein domains;
26-121 8.31e-09

Insect pheromone/odorant binding protein domains;


Pssm-ID: 214783  Cd Length: 103  Bit Score: 49.35  E-value: 8.31e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268055390    26 AEGCLKHHNLTSAQV-QAVAPSTPVADVPvAVKCYSRCLI--QDYFGDDGKIDLQKVGKR------GSQEDHVILSQCKQ 96
Cdd:smart00708   2 REECKKELGVSEADLaDFVKFWREDYPDE-KVKCYIKCVLkkLGLMDDDGKFDAEKLLEQlkaddeMAEELEDIIEKCEK 80

                           90       100
                   ....*....|....*....|....*
gi 268055390    97 QFDgvTNLDTCDYPYLILQCYFKGK 121
Cdd:smart00708  81 KKG--TEEDPCDTAYRVAKCFKKAI 103
PBP_GOBP pfam01395
PBP/GOBP family; The olfactory receptors of terrestrial animals exist in an aqueous ...
 25-119 5.62e-03

PBP/GOBP family; The olfactory receptors of terrestrial animals exist in an aqueous environment, yet detect odorants that are primarily hydrophobic. The aqueous solubility of hydrophobic odorants is thought to be greatly enhanced via odorant binding proteins which exist in the extracellular fluid surrounding the odorant receptors. This family is composed of pheromone binding proteins (PBP), which are male-specific and associate with pheromone-sensitive neurons and general-odorant binding proteins (GOBP).


Pssm-ID: 460193  Cd Length: 109  Bit Score: 33.99  E-value: 5.62e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268055390   25 NAEGCLKHHNLTSAQVQAVAPSTPVADVPVavKCYSRCLIQ--DYFGDDGKIDLQKVG---KRGSQEDHVILSQCKQQFD 99
Cdd:pfam01395  13 ARKECAKELGVSDEDVEKLKKGEFPDDDET--KCYIRCVLKklGLMDDDGGLNKDVLLeqlEPVLDDEKAKEIIEKCQAG 90

                          90       100
                  ....*....|....*....|
gi 268055390  100 GVTnlDTCDYPYLILQCYFK 119
Cdd:pfam01395  91 AVK--DPCETAYKLFKCFYK 108
 
Name Accession Description Interval E-value
PhBP smart00708
Insect pheromone/odorant binding protein domains;
26-121 8.31e-09

Insect pheromone/odorant binding protein domains;


Pssm-ID: 214783  Cd Length: 103  Bit Score: 49.35  E-value: 8.31e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268055390    26 AEGCLKHHNLTSAQV-QAVAPSTPVADVPvAVKCYSRCLI--QDYFGDDGKIDLQKVGKR------GSQEDHVILSQCKQ 96
Cdd:smart00708   2 REECKKELGVSEADLaDFVKFWREDYPDE-KVKCYIKCVLkkLGLMDDDGKFDAEKLLEQlkaddeMAEELEDIIEKCEK 80

                           90       100
                   ....*....|....*....|....*
gi 268055390    97 QFDgvTNLDTCDYPYLILQCYFKGK 121
Cdd:smart00708  81 KKG--TEEDPCDTAYRVAKCFKKAI 103
PBP_GOBP pfam01395
PBP/GOBP family; The olfactory receptors of terrestrial animals exist in an aqueous ...
 25-119 5.62e-03

PBP/GOBP family; The olfactory receptors of terrestrial animals exist in an aqueous environment, yet detect odorants that are primarily hydrophobic. The aqueous solubility of hydrophobic odorants is thought to be greatly enhanced via odorant binding proteins which exist in the extracellular fluid surrounding the odorant receptors. This family is composed of pheromone binding proteins (PBP), which are male-specific and associate with pheromone-sensitive neurons and general-odorant binding proteins (GOBP).


Pssm-ID: 460193  Cd Length: 109  Bit Score: 33.99  E-value: 5.62e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268055390   25 NAEGCLKHHNLTSAQVQAVAPSTPVADVPVavKCYSRCLIQ--DYFGDDGKIDLQKVG---KRGSQEDHVILSQCKQQFD 99
Cdd:pfam01395  13 ARKECAKELGVSDEDVEKLKKGEFPDDDET--KCYIRCVLKklGLMDDDGGLNKDVLLeqlEPVLDDEKAKEIIEKCQAG 90

                          90       100
                  ....*....|....*....|
gi 268055390  100 GVTnlDTCDYPYLILQCYFK 119
Cdd:pfam01395  91 AVK--DPCETAYKLFKCFYK 108
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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