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Conserved domains on  [gi|288895135|gb|ADC66672|]
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protein of unknown function DUF101 [Ferroglobus placidus DSM 10642]

Protein Classification

archease( domain architecture ID 10487813)

archease catalyzes the activation of the RNA ligase RtcB, which joins RNA molecules to form phosphodiester bonds

CATH:  3.55.10.10
Gene Ontology:  GO:0006388|GO:0046872|GO:0072669
SCOP:  4003521

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Archease pfam01951
Archease protein family (MTH1598/TM1083); This archease family of proteins, has two SHS2 ...
2-133 1.14e-40

Archease protein family (MTH1598/TM1083); This archease family of proteins, has two SHS2 domains, with one inserted into another. It is predicted to be an enzyme. It is predicted to act as a chaperone in DNA/RNA metabolism.


:

Pssm-ID: 426527  Cd Length: 136  Bit Score: 131.88  E-value: 1.14e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288895135    2 YRFVEHTADIAFEVEAESLEELFIDAANAFYEAFCNRDLVKEEEERRLELEEEDVEHLLYSWLNEILFLFDAEHFAAKRV 81
Cdd:pfam01951   1 YEYLDHTADVGIEAWGPTLEEAFENAALAMFELMTDLSKVEPKEEREIEVEGEDLEDLLVDWLDELLYLFDTEGLVFSRF 80
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 288895135   82 EVSVENN--SLKARLIGGKITPE--AVKLEPKAITMHKFRVERKDGKFYAFVIIDI 133
Cdd:pfam01951  81 EIEEEEDgyRLEATAYGEPFDPEkhEPKTEVKAVTYHELRIEKEDGGWEAQVVVDI 136
 
Name Accession Description Interval E-value
Archease pfam01951
Archease protein family (MTH1598/TM1083); This archease family of proteins, has two SHS2 ...
2-133 1.14e-40

Archease protein family (MTH1598/TM1083); This archease family of proteins, has two SHS2 domains, with one inserted into another. It is predicted to be an enzyme. It is predicted to act as a chaperone in DNA/RNA metabolism.


Pssm-ID: 426527  Cd Length: 136  Bit Score: 131.88  E-value: 1.14e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288895135    2 YRFVEHTADIAFEVEAESLEELFIDAANAFYEAFCNRDLVKEEEERRLELEEEDVEHLLYSWLNEILFLFDAEHFAAKRV 81
Cdd:pfam01951   1 YEYLDHTADVGIEAWGPTLEEAFENAALAMFELMTDLSKVEPKEEREIEVEGEDLEDLLVDWLDELLYLFDTEGLVFSRF 80
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 288895135   82 EVSVENN--SLKARLIGGKITPE--AVKLEPKAITMHKFRVERKDGKFYAFVIIDI 133
Cdd:pfam01951  81 EIEEEEDgyRLEATAYGEPFDPEkhEPKTEVKAVTYHELRIEKEDGGWEAQVVVDI 136
ARCH COG1371
Archease, activates RNA ligation by RtcB (tRNA splicing) [Translation, ribosomal structure and ...
2-133 2.52e-40

Archease, activates RNA ligation by RtcB (tRNA splicing) [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440982  Cd Length: 139  Bit Score: 131.45  E-value: 2.52e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288895135   2 YRFVEHTADIAFEVEAESLEELFIDAANAFYEAFCNRDLVKEEEERRLELEEEDVEHLLYSWLNEILFLFDAEHFAAKRV 81
Cdd:COG1371    3 YEFLDHTADVGIEAYGPTLEEAFANAALALFALMVDTSKVEPREEREIEVEAEDLEDLLVDWLNELLYLFDTEGLLFSRF 82
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 288895135  82 EVSVENN---SLKARLIGGKITPE--AVKLEPKAITMHKFRVERKDGKFYAFVIIDI 133
Cdd:COG1371   83 EVEIEENggyRLEATARGEPLDPErhEFKVEVKAVTYHELRVEQEDGGWRAQVVVDV 139
Archease PRK00407
Archease protein family (MTH1598/TM1083); This archease family of proteins, has two SHS2 ...
2-133 1.73e-20

Archease protein family (MTH1598/TM1083); This archease family of proteins, has two SHS2 domains, with one inserted into another. It is predicted to be an enzyme. It is predicted to act as a chaperone in DNA/RNA metabolism.


Pssm-ID: 179008  Cd Length: 139  Bit Score: 80.83  E-value: 1.73e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288895135   2 YRFVEHTADIAFEVEAESLEELFIDAANAFYEAFCNRDLVKEEEERRLELEEEDVEHLLYSWLNEILFLFDAEH--FAAK 79
Cdd:PRK00407   4 YEFFEHTADIGIRAYGRTLEEAFENAALAVFDVITDTSKVEPKEEREIEIEGYDLENLLYRWLEELLYYYDSEGlvFSKF 83
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 288895135  80 RVEVSVENNSLKARLIGGKITPEavKLEP----KAITMHKFRVERKDGKFYAFVIIDI 133
Cdd:PRK00407  84 DVKIDEDDMTLKAKAWGEKFDPE--IHERrtvvKAMTYHDMEIEKEDGCWMAQFVVDI 139
 
Name Accession Description Interval E-value
Archease pfam01951
Archease protein family (MTH1598/TM1083); This archease family of proteins, has two SHS2 ...
2-133 1.14e-40

Archease protein family (MTH1598/TM1083); This archease family of proteins, has two SHS2 domains, with one inserted into another. It is predicted to be an enzyme. It is predicted to act as a chaperone in DNA/RNA metabolism.


Pssm-ID: 426527  Cd Length: 136  Bit Score: 131.88  E-value: 1.14e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288895135    2 YRFVEHTADIAFEVEAESLEELFIDAANAFYEAFCNRDLVKEEEERRLELEEEDVEHLLYSWLNEILFLFDAEHFAAKRV 81
Cdd:pfam01951   1 YEYLDHTADVGIEAWGPTLEEAFENAALAMFELMTDLSKVEPKEEREIEVEGEDLEDLLVDWLDELLYLFDTEGLVFSRF 80
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 288895135   82 EVSVENN--SLKARLIGGKITPE--AVKLEPKAITMHKFRVERKDGKFYAFVIIDI 133
Cdd:pfam01951  81 EIEEEEDgyRLEATAYGEPFDPEkhEPKTEVKAVTYHELRIEKEDGGWEAQVVVDI 136
ARCH COG1371
Archease, activates RNA ligation by RtcB (tRNA splicing) [Translation, ribosomal structure and ...
2-133 2.52e-40

Archease, activates RNA ligation by RtcB (tRNA splicing) [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440982  Cd Length: 139  Bit Score: 131.45  E-value: 2.52e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288895135   2 YRFVEHTADIAFEVEAESLEELFIDAANAFYEAFCNRDLVKEEEERRLELEEEDVEHLLYSWLNEILFLFDAEHFAAKRV 81
Cdd:COG1371    3 YEFLDHTADVGIEAYGPTLEEAFANAALALFALMVDTSKVEPREEREIEVEAEDLEDLLVDWLNELLYLFDTEGLLFSRF 82
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 288895135  82 EVSVENN---SLKARLIGGKITPE--AVKLEPKAITMHKFRVERKDGKFYAFVIIDI 133
Cdd:COG1371   83 EVEIEENggyRLEATARGEPLDPErhEFKVEVKAVTYHELRVEQEDGGWRAQVVVDV 139
Archease PRK00407
Archease protein family (MTH1598/TM1083); This archease family of proteins, has two SHS2 ...
2-133 1.73e-20

Archease protein family (MTH1598/TM1083); This archease family of proteins, has two SHS2 domains, with one inserted into another. It is predicted to be an enzyme. It is predicted to act as a chaperone in DNA/RNA metabolism.


Pssm-ID: 179008  Cd Length: 139  Bit Score: 80.83  E-value: 1.73e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288895135   2 YRFVEHTADIAFEVEAESLEELFIDAANAFYEAFCNRDLVKEEEERRLELEEEDVEHLLYSWLNEILFLFDAEH--FAAK 79
Cdd:PRK00407   4 YEFFEHTADIGIRAYGRTLEEAFENAALAVFDVITDTSKVEPKEEREIEIEGYDLENLLYRWLEELLYYYDSEGlvFSKF 83
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 288895135  80 RVEVSVENNSLKARLIGGKITPEavKLEP----KAITMHKFRVERKDGKFYAFVIIDI 133
Cdd:PRK00407  84 DVKIDEDDMTLKAKAWGEKFDPE--IHERrtvvKAMTYHDMEIEKEDGCWMAQFVVDI 139
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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