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Conserved domains on  [gi|314911965|gb|ADT63728|]
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ATP synthase F0 subunit 6, partial (mitochondrion) [Nannoperca oxleyana]

Protein Classification

ATP synthase F0 subunit 6( domain architecture ID 10009577)

ATP synthase F0 subunit 6 is part of the mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V), which produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ATP6 MTH00132
ATP synthase F0 subunit 6; Provisional
 1-179 1.53e-111

ATP synthase F0 subunit 6; Provisional


:

Pssm-ID: 177190  Cd Length: 227  Bit Score: 316.82  E-value: 1.53e-111
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911965   1 MTLSFFDQFMSPVFLGIPLIAIALVLPCIIFPTPTTRWLNNRLLAMQNWFINQFTSQLFLPLNPGAHKWAMVFMSLMLFL 80
Cdd:MTH00132   1 MTLSFFDQFMSPTYLGIPLIALALTLPWILFPTPTSRWLNNRLLTLQGWFINRFTQQLLLPLNVGGHKWALLLTSLMLFL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911965  81 ISLNMLGLLPYTFTPTTQLSLNMGLAVPLWLATVIIGMRNQPTIALGHLLPEGTPTPLIPVLIIIETISHLMRPLALGVR 160
Cdd:MTH00132  81 ITLNMLGLLPYTFTPTTQLSLNMGLAVPLWLATVIIGMRNQPTHALGHLLPEGTPTPLIPVLIIIETISLFIRPLALGVR 160

                        170
                 ....*....|....*....
gi 314911965 161 LTANLTAGHLLIQLIATAA 179
Cdd:MTH00132 161 LTANLTAGHLLIQLIATAA 179
 
Name Accession Description Interval E-value
ATP6 MTH00132
ATP synthase F0 subunit 6; Provisional
 1-179 1.53e-111

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177190  Cd Length: 227  Bit Score: 316.82  E-value: 1.53e-111
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911965   1 MTLSFFDQFMSPVFLGIPLIAIALVLPCIIFPTPTTRWLNNRLLAMQNWFINQFTSQLFLPLNPGAHKWAMVFMSLMLFL 80
Cdd:MTH00132   1 MTLSFFDQFMSPTYLGIPLIALALTLPWILFPTPTSRWLNNRLLTLQGWFINRFTQQLLLPLNVGGHKWALLLTSLMLFL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911965  81 ISLNMLGLLPYTFTPTTQLSLNMGLAVPLWLATVIIGMRNQPTIALGHLLPEGTPTPLIPVLIIIETISHLMRPLALGVR 160
Cdd:MTH00132  81 ITLNMLGLLPYTFTPTTQLSLNMGLAVPLWLATVIIGMRNQPTHALGHLLPEGTPTPLIPVLIIIETISLFIRPLALGVR 160

                        170
                 ....*....|....*....
gi 314911965 161 LTANLTAGHLLIQLIATAA 179
Cdd:MTH00132 161 LTANLTAGHLLIQLIATAA 179
ATP_synt_6_or_A TIGR01131
ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Bacterial forms should be ...
 4-179 7.44e-41

ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Bacterial forms should be designated ATP synthase, F0 subunit A; eukaryotic (chloroplast and mitochondrial) forms should be designated ATP synthase, F0 subunit 6. The F1/F0 ATP synthase is a multisubunit, membrane associated enzyme found in bacteria and mitochondria and chloroplast. This enzyme is principally involved in the synthesis of ATP from ADP and inorganic phosphate by coupling the energy derived from the proton electrochemical gradient across the biological membrane. A brief description of this multisubunit enzyme complex: F1 and F0 represent two major clusters of subunits. Individual subunits in each of these clusters are named differently in prokaryotes and in organelles e.g., mitochondria and chloroplast. The bacterial equivalent of subunit 6 is named subunit 'A'. It has been shown that proton is conducted though this subunit. Typically, deprotonation and reprotonation of the acidic amino acid side-chains are implicated in the process. [Energy metabolism, ATP-proton motive force interconversion]


Pssm-ID: 273458  Cd Length: 226  Bit Score: 137.34  E-value: 7.44e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911965    4 SFFDQFMSPVFLGIPLIAIALVLPCIIFPTPTTRWL-NNRLLAMQNWFINQFTSQLFLPLNPGAHKWAMVFMSLMLFLIS 82
Cdd:TIGR01131   4 QFDISPITLFSLTLLSLILLLSLLIFLISSSLSRWLiPSRWQNLMESIYEFVLSIVKSQIGGKKGKFFPLIFTLFLFILI 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911965   83 LNMLGLLPYTFTPTTQLSLNMGLAVPLWLATVIIGMRNQPTIALGHLLPEGTPTPLIPVLIIIETISHLMRPLALGVRLT 162
Cdd:TIGR01131  84 SNLLGLIPYSFTPTSHLSFTLGLALPLWLGLTISGFRKHPKGFLAHLVPSGTPLPLIPFLVIIETISYLARPISLSVRLF 163

                         170
                  ....*....|....*..
gi 314911965  163 ANLTAGHLLIQLIATAA 179
Cdd:TIGR01131 164 ANISAGHLLLTLLSGLL 180
ATP-synt_Fo_a_6 cd00310
ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms ...
 66-179 5.85e-30

ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms are designated as ATP synthase, Fo complex, subunit a; eukaryotic (chloroplast and mitochondrial) forms are designated as ATP synthase, Fo complex, subunit 6. The F-ATP synthases (also called FoF1-ATPases) consist of two structural domains: F1 (factor one) complex containing the soluble catalytic core, and Fo (oligomycin sensitive factor) complex containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. F-ATP synthases are primarily found in the inner membranes of eukaryotic mitochondria, in the thylakoid membranes of chloroplasts or in the plasma membranes of bacteria. F-ATP synthase has also been found in the archaea Methanosarcina acetivorans. F-ATP synthases are the primary producers of ATP, using the proton gradient generated by oxidative phosphorylation (mitochondria) or photosynthesis (chloroplasts). Alternatively, under conditions of low driving force, ATP synthases function as ATPases, thus generating a transmembrane proton or Na(+) gradient at the expense of energy derived from ATP hydrolysis.


Pssm-ID: 349411 [Multi-domain]  Cd Length: 156  Bit Score: 107.10  E-value: 5.85e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911965  66 AHKWAMVFMSLMLFLISLNMLGLLPYTFTPTTQLSLNMGLAVPLWLATVIIGMRNQPTIALGHLLPEGTPTPLIPVLIII 145
Cdd:cd00310    1 GKKYLPLLGTLFLFILFSNLLGLIPYSFTPTSHLNVTLALALIVFLGVHILGIKKHGLGFFLHFLPPGTPLPLAPLMVPI 80

                         90       100       110
                 ....*....|....*....|....*....|....
gi 314911965 146 ETISHLMRPLALGVRLTANLTAGHLLIQLIATAA 179
Cdd:cd00310   81 ELISELIRPLSLSVRLFANMFAGHLLLALLSGLV 114
ATP-synt_A pfam00119
ATP synthase A chain;
19-179 5.56e-23

ATP synthase A chain;


Pssm-ID: 459679 [Multi-domain]  Cd Length: 216  Bit Score: 90.63  E-value: 5.56e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911965   19 LIAIALVLPCIIFPTP-TTRWLNNRLLAMQNWFINQFTSQLFLPLNP-GAHKWAMVFMSLMLFLISLNMLGLL---PYTF 93
Cdd:pfam00119   5 LIVALILLLFLLLATRkTKKLVPGRLQNFVEMLVEFVDNIVKDNIGKkKGRKFFPLLLTLFFFILVSNLLGLIpksPGGF 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911965   94 TPTTQLSLNMGLAVPLWLATVIIGMRNQPTIA-LGHLLPEGTPTPLIPVLIIIETISHLMRPLALGVRLTANLTAGHLLI 172
Cdd:pfam00119  85 TVTADINVTLALALIVFLLVHYYGIKKHGLGGyFKKLFVPPVPLPLVPLLLPIEIISEFARPVSLSLRLFGNMLAGHLLL 164


                  ....*..
gi 314911965  173 QLIATAA 179
Cdd:pfam00119 165 LLLAGLI 171
AtpB COG0356
FoF1-type ATP synthase, membrane subunit a [Energy production and conversion]; FoF1-type ATP ...
 66-179 6.55e-17

FoF1-type ATP synthase, membrane subunit a [Energy production and conversion]; FoF1-type ATP synthase, membrane subunit a is part of the Pathway/BioSystem: FoF1-type ATP synthase


Pssm-ID: 440125 [Multi-domain]  Cd Length: 212  Bit Score: 74.72  E-value: 6.55e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911965  66 AHKWAMVFMSLMLFLISLNMLGLLPYTFTPTTQLSLNMGLAVPLWLATVIIGMRNQPTIA-LGHLLPEGTPtPLIPVLII 144
Cdd:COG0356   54 GRKFAPLLLTLFLFILVSNLLGLIPGLFPPTADINVTLALALIVFVLVHYYGIKKKGLGGyLKHLFFPPFP-WLAPLMLP 132

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 314911965 145 IETISHLMRPLALGVRLTANLTAGHLLIQLIATAA 179
Cdd:COG0356  133 IEIISELARPLSLSLRLFGNMFAGHIILLLLAGLA 167
 
Name Accession Description Interval E-value
ATP6 MTH00132
ATP synthase F0 subunit 6; Provisional
 1-179 1.53e-111

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177190  Cd Length: 227  Bit Score: 316.82  E-value: 1.53e-111
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911965   1 MTLSFFDQFMSPVFLGIPLIAIALVLPCIIFPTPTTRWLNNRLLAMQNWFINQFTSQLFLPLNPGAHKWAMVFMSLMLFL 80
Cdd:MTH00132   1 MTLSFFDQFMSPTYLGIPLIALALTLPWILFPTPTSRWLNNRLLTLQGWFINRFTQQLLLPLNVGGHKWALLLTSLMLFL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911965  81 ISLNMLGLLPYTFTPTTQLSLNMGLAVPLWLATVIIGMRNQPTIALGHLLPEGTPTPLIPVLIIIETISHLMRPLALGVR 160
Cdd:MTH00132  81 ITLNMLGLLPYTFTPTTQLSLNMGLAVPLWLATVIIGMRNQPTHALGHLLPEGTPTPLIPVLIIIETISLFIRPLALGVR 160

                        170
                 ....*....|....*....
gi 314911965 161 LTANLTAGHLLIQLIATAA 179
Cdd:MTH00132 161 LTANLTAGHLLIQLIATAA 179
ATP6 MTH00073
ATP synthase F0 subunit 6; Provisional
 1-179 3.20e-93

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177144  Cd Length: 227  Bit Score: 270.30  E-value: 3.20e-93
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911965   1 MTLSFFDQFMSPVFLGIPLIAIALVLPCIIFPTPTTRWLNNRLLAMQNWFINQFTSQLFLPLNPGAHKWAMVFMSLMLFL 80
Cdd:MTH00073   1 MNLSFFDQFLSPTLLGIPLIMLAMLLPWLLFPTPTNKWLNNRLSTLQIWFLQNFTKQLMLPLNTPGHKWALILTSLMVFL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911965  81 ISLNMLGLLPYTFTPTTQLSLNMGLAVPLWLATVIIGMRNQPTIALGHLLPEGTPTPLIPVLIIIETISHLMRPLALGVR 160
Cdd:MTH00073  81 ITMNLLGLLPYTFTPTTQLSLNLGLAVPLWLATVLIGLRNQPTASLGHLLPEGTPTLLIPILIIIETISLFIRPLALGVR 160

                        170
                 ....*....|....*....
gi 314911965 161 LTANLTAGHLLIQLIATAA 179
Cdd:MTH00073 161 LTANLTAGHLLIQLISTAT 179
ATP6 MTH00120
ATP synthase F0 subunit 6; Provisional
 1-179 9.12e-87

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177181  Cd Length: 227  Bit Score: 253.98  E-value: 9.12e-87
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911965   1 MTLSFFDQFMSPVFLGIPLIAIALVLPCIIFPTPTTRWLNNRLLAMQNWFINQFTSQLFLPLNPGAHKWAMVFMSLMLFL 80
Cdd:MTH00120   1 MNLNFFDQFSSPELLGIPLILLAMLIPALLIPSPKNRLLTNRLTTLQLWLIKLITKQLMLPLNKKGHKWALILTSLMLLL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911965  81 ISLNMLGLLPYTFTPTTQLSLNMGLAVPLWLATVIIGMRNQPTIALGHLLPEGTPTPLIPVLIIIETISHLMRPLALGVR 160
Cdd:MTH00120  81 LLINLLGLLPYTFTPTTQLSMNMALAIPLWLATVLTGLRNQPTTSLAHLLPEGTPTPLIPALILIETISLLIRPLALGVR 160

                        170
                 ....*....|....*....
gi 314911965 161 LTANLTAGHLLIQLIATAA 179
Cdd:MTH00120 161 LTANLTAGHLLIQLISTAT 179
ATP6 MTH00179
ATP synthase F0 subunit 6; Provisional
 1-179 1.54e-75

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177230  Cd Length: 227  Bit Score: 225.60  E-value: 1.54e-75
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911965   1 MTLSFFDQFMSPVFLGIPLIAIALVLPCIIFPTPTTRWLNNRLLAMQNWFINQFTSQLFLPLNPGAHKWAMVFMSLMLFL 80
Cdd:MTH00179   1 MMLSMFDQFESPSLLGIPLLALALLLPWLLFPSLTNRWLNNRLSTLQSWFFGSFTFQLMQPINKKGHKWAVLFLSLMLFL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911965  81 ISLNMLGLLPYTFTPTTQLSLNMGLAVPLWLATVIIGMRNQPTIALGHLLPEGTPTPLIPVLIIIETISHLMRPLALGVR 160
Cdd:MTH00179  81 LTLNLLGLLPYTFTPTTQLSLNLGLALPLWLGTVLYGLFNQPTIALAHLLPEGTPTPLIPMLVWIETISLLIRPLALGVR 160

                        170
                 ....*....|....*....
gi 314911965 161 LTANLTAGHLLIQLIATAA 179
Cdd:MTH00179 161 LTANITAGHLLMHLISSAV 179
ATP6 MTH00101
ATP synthase F0 subunit 6; Validated
 1-179 6.39e-62

ATP synthase F0 subunit 6; Validated


Pssm-ID: 177163  Cd Length: 226  Bit Score: 190.93  E-value: 6.39e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911965   1 MTLSFFDQFMSPVFLGIPLIAIALVLPCIIFPTPTtRWLNNRLLAMQNWFINQFTSQLFLPLNPGAHKWAMVFMSLMLFL 80
Cdd:MTH00101   1 MNENLFASFITPTILGLPIVTLIIMFPSLLFPTPN-RLINNRLISIQQWLIQLTSKQMMTIHNTKGQTWSLMLMSLILFI 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911965  81 ISLNMLGLLPYTFTPTTQLSLNMGLAVPLWLATVIIGMRNQPTIALGHLLPEGTPTPLIPVLIIIETISHLMRPLALGVR 160
Cdd:MTH00101  80 GSTNLLGLLPHSFTPTTQLSMNLGMAIPLWAGTVITGFRNKTKASLAHFLPQGTPTPLIPMLVIIETISLFIQPMALAVR 159

                        170
                 ....*....|....*....
gi 314911965 161 LTANLTAGHLLIQLIATAA 179
Cdd:MTH00101 160 LTANITAGHLLIHLIGGAT 178
ATP_synt_6_or_A TIGR01131
ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Bacterial forms should be ...
 4-179 7.44e-41

ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Bacterial forms should be designated ATP synthase, F0 subunit A; eukaryotic (chloroplast and mitochondrial) forms should be designated ATP synthase, F0 subunit 6. The F1/F0 ATP synthase is a multisubunit, membrane associated enzyme found in bacteria and mitochondria and chloroplast. This enzyme is principally involved in the synthesis of ATP from ADP and inorganic phosphate by coupling the energy derived from the proton electrochemical gradient across the biological membrane. A brief description of this multisubunit enzyme complex: F1 and F0 represent two major clusters of subunits. Individual subunits in each of these clusters are named differently in prokaryotes and in organelles e.g., mitochondria and chloroplast. The bacterial equivalent of subunit 6 is named subunit 'A'. It has been shown that proton is conducted though this subunit. Typically, deprotonation and reprotonation of the acidic amino acid side-chains are implicated in the process. [Energy metabolism, ATP-proton motive force interconversion]


Pssm-ID: 273458  Cd Length: 226  Bit Score: 137.34  E-value: 7.44e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911965    4 SFFDQFMSPVFLGIPLIAIALVLPCIIFPTPTTRWL-NNRLLAMQNWFINQFTSQLFLPLNPGAHKWAMVFMSLMLFLIS 82
Cdd:TIGR01131   4 QFDISPITLFSLTLLSLILLLSLLIFLISSSLSRWLiPSRWQNLMESIYEFVLSIVKSQIGGKKGKFFPLIFTLFLFILI 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911965   83 LNMLGLLPYTFTPTTQLSLNMGLAVPLWLATVIIGMRNQPTIALGHLLPEGTPTPLIPVLIIIETISHLMRPLALGVRLT 162
Cdd:TIGR01131  84 SNLLGLIPYSFTPTSHLSFTLGLALPLWLGLTISGFRKHPKGFLAHLVPSGTPLPLIPFLVIIETISYLARPISLSVRLF 163

                         170
                  ....*....|....*..
gi 314911965  163 ANLTAGHLLIQLIATAA 179
Cdd:TIGR01131 164 ANISAGHLLLTLLSGLL 180
ATP6 MTH00035
ATP synthase F0 subunit 6; Validated
 4-178 1.17e-39

ATP synthase F0 subunit 6; Validated


Pssm-ID: 177110  Cd Length: 229  Bit Score: 134.33  E-value: 1.17e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911965   4 SFFDQFMSPVFLGIPLIAIALVLPCI-IFPTPTTRWLNNRLLAMQNWFINQFTSQLFLPLNPGAHKWAMVFMSLMLFLIS 82
Cdd:MTH00035   6 SIFGQFSPDTILFIPLTLLSSVIALSwLFFINPTNWLPSRSQSIWLTFRQEILKLIFQNTNPNTAPWAGLLTTVFILILS 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911965  83 LNMLGLLPYTFTPTTQLSLNMGLAVPLWLATVIIGMRNQPTIALGHLLPEGTPTPLIPVLIIIETISHLMRPLALGVRLT 162
Cdd:MTH00035  86 INVLGLFPYAFTSTSHISLTYSLGIPLWMSVNILGFYLAFNSRLSHLVPQGTPSFLIPLMVWIETLSLFAQPIALGLRLA 165

                        170
                 ....*....|....*.
gi 314911965 163 ANLTAGHLLIQLIATA 178
Cdd:MTH00035 166 ANLTAGHLLIFLLSTA 181
ATP6 MTH00157
ATP synthase F0 subunit 6; Provisional
 1-175 8.38e-34

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 214441  Cd Length: 223  Bit Score: 119.12  E-value: 8.38e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911965   1 MTLSFFDQFMSPVFLGIPLIAIALVLPCIIFPTptTRWL-NNRLLAMQNWFINQFTSQLFLPLNPGAHKWAMVFMSLMLF 79
Cdd:MTH00157   1 MMTNLFSIFDPSTSFNLSLNWLSTFLGLLFIPS--SFWLiPSRYNILWNKILKTLHKEFKTLLGPKNKGSTLIFISLFSF 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911965  80 LISLNMLGLLPYTFTPTTQLSLNMGLAVPLWLATVIIGMRNQPTIALGHLLPEGTPTPLIPVLIIIETISHLMRPLALGV 159
Cdd:MTH00157  79 ILFNNFLGLFPYIFTSTSHLSLTLSLALPLWLSFMLFGWINNTNHMFAHLVPQGTPPILMPFMVLIETISNLIRPGTLAV 158

                        170
                 ....*....|....*.
gi 314911965 160 RLTANLTAGHLLIQLI 175
Cdd:MTH00157 159 RLAANMIAGHLLLTLL 174
ATP6 MTH00176
ATP synthase F0 subunit 6; Provisional
 1-178 1.30e-31

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 214449  Cd Length: 229  Bit Score: 113.59  E-value: 1.30e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911965   1 MTLSFFDQFMSPVFLGIPLIAIALVLPCI-IFPTPTTRWL-NNRLLAMQNWFINQFTSQLFLPLNPGAHKWAMVFMSLML 78
Cdd:MTH00176   1 MLVDLFSSFDPPNKNIFSMISLSWITLLLfLLLMPSSVWFcPSKLQVFMLMFSTFLPEMILRSNGSYILGSASIIISLFI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911965  79 FLISLNMLGLLPYTFTPTTQLSLNMGLAVPLWLATVIIGMRNQPTIALGHLLPEGTPTPLIPVLIIIETISHLMRPLALG 158
Cdd:MTH00176  81 LVMSLNLSGLIPYVFTSTSHLVITLSLALPLWLGVILSGFINNFYSRLSHLVPQGTPPLLNPFLVLIELVSLLIRPLTLA 160

                        170       180
                 ....*....|....*....|
gi 314911965 159 VRLTANLTAGHLLIQLIATA 178
Cdd:MTH00176 161 VRLAANLSAGHLLLGLLGAA 180
ATP6 MTH00173
ATP synthase F0 subunit 6; Provisional
 4-176 1.67e-30

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 214448  Cd Length: 231  Bit Score: 110.73  E-value: 1.67e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911965   4 SFFDQFMSPVFLGIPLIAIALVLPCIIFPTPTTrWLNNRLLAMQNWFINQFTSQLFLPLNPGAHKWAMVFMSLMLFLISL 83
Cdd:MTH00173   7 SSFDDHNSSFSSLSFLMWLLSLMSLFFFSSSVW-VSSSNLSSVFKLFVLTVSSQVTRSSGLNLGGFSLLLSSLFLFLISL 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911965  84 NMLGLLPYTFTPTTQLSLNMGLAVPLWLATVIIGMRNQPTIALGHLLPEGTPTPLIPVLIIIETISHLMRPLALGVRLTA 163
Cdd:MTH00173  86 NLSGLLPFVFSVTSHLAFTFSLALPLWLSLILSGLFYNPSKSLAGLVPAGAPAGLNPFLVLIETVSILIRPLTLTVRLLA 165

                        170
                 ....*....|...
gi 314911965 164 NLTAGHLLIQLIA 176
Cdd:MTH00173 166 NISAGHIVLTLIG 178
ATP-synt_Fo_a_6 cd00310
ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms ...
 66-179 5.85e-30

ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms are designated as ATP synthase, Fo complex, subunit a; eukaryotic (chloroplast and mitochondrial) forms are designated as ATP synthase, Fo complex, subunit 6. The F-ATP synthases (also called FoF1-ATPases) consist of two structural domains: F1 (factor one) complex containing the soluble catalytic core, and Fo (oligomycin sensitive factor) complex containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. F-ATP synthases are primarily found in the inner membranes of eukaryotic mitochondria, in the thylakoid membranes of chloroplasts or in the plasma membranes of bacteria. F-ATP synthase has also been found in the archaea Methanosarcina acetivorans. F-ATP synthases are the primary producers of ATP, using the proton gradient generated by oxidative phosphorylation (mitochondria) or photosynthesis (chloroplasts). Alternatively, under conditions of low driving force, ATP synthases function as ATPases, thus generating a transmembrane proton or Na(+) gradient at the expense of energy derived from ATP hydrolysis.


Pssm-ID: 349411 [Multi-domain]  Cd Length: 156  Bit Score: 107.10  E-value: 5.85e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911965  66 AHKWAMVFMSLMLFLISLNMLGLLPYTFTPTTQLSLNMGLAVPLWLATVIIGMRNQPTIALGHLLPEGTPTPLIPVLIII 145
Cdd:cd00310    1 GKKYLPLLGTLFLFILFSNLLGLIPYSFTPTSHLNVTLALALIVFLGVHILGIKKHGLGFFLHFLPPGTPLPLAPLMVPI 80

                         90       100       110
                 ....*....|....*....|....*....|....
gi 314911965 146 ETISHLMRPLALGVRLTANLTAGHLLIQLIATAA 179
Cdd:cd00310   81 ELISELIRPLSLSVRLFANMFAGHLLLALLSGLV 114
ATP6 MTH00172
ATP synthase F0 subunit 6; Provisional
 1-176 1.16e-23

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 214447  Cd Length: 232  Bit Score: 93.18  E-value: 1.16e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911965   1 MTLSFFDQFMSPVFLG--------IPLIAIALVLPCIIFPTPTtrwlnnRLLAMQNWFINQFTSQLFLPLNPGAHKWAMV 72
Cdd:MTH00172   1 MSSSYFDQFNIVWLIGltnssimmILVIIVVLLLFKGIKLIPK------RWQSIIEIIYNHFHGVVKDNLGNEGLKYFPF 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911965  73 FMSLMLFLISLNMLGLLPYTFTPTTQLSLNMGLAVPLWLATVIIGMRNQPTIALGHLLPEGTPTPLIPVLIIIETISHLM 152
Cdd:MTH00172  75 IISLFFFIVFLNLLGLFPYVFTPTTHIVVTLGLSFSIIIGVTLAGFWRFKWDFFSILMPSGAPLGLAPLLVLIETVSYIS 154

                        170       180
                 ....*....|....*....|....
gi 314911965 153 RPLALGVRLTANLTAGHLLIQLIA 176
Cdd:MTH00172 155 RAISLGVRLAANLSAGHLLFAILA 178
ATP6 MTH00005
ATP synthase F0 subunit 6; Provisional
 4-179 3.25e-23

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 164583  Cd Length: 231  Bit Score: 91.72  E-value: 3.25e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911965   4 SFFDQFMSPVFLGIPLIAIALVLPCIIFPTPTTRWL-NNRLLAMQNWFINQFTSQLFLPLNPGAHKWAMVFMSLMLFLIS 82
Cdd:MTH00005   7 SSFDPATNSLFNNLSSTAFWAFNFSIILLLSSSFWItPNRLSSIMSPPKSTMHTQLSRTFGKHLKGFSSLISALFTMIIL 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911965  83 LNMLGLLPYTFTPTTQLSLNMGLAVPLWLATVIIGMRNQPTIALGHLLPEGTPTPLIPVLIIIETISHLMRPLALGVRLT 162
Cdd:MTH00005  87 MNLSGLLPYVFSTSSHLIFTLTLGLPLWLSLIMSSVTFSPKKFAAHLLPGGAPDWLNPFLVLIETISILVRPITLSFRLA 166

                        170
                 ....*....|....*..
gi 314911965 163 ANLTAGHLLIQLIATAA 179
Cdd:MTH00005 167 ANMSAGHIVLSLIGIYA 183
ATP-synt_A pfam00119
ATP synthase A chain;
19-179 5.56e-23

ATP synthase A chain;


Pssm-ID: 459679 [Multi-domain]  Cd Length: 216  Bit Score: 90.63  E-value: 5.56e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911965   19 LIAIALVLPCIIFPTP-TTRWLNNRLLAMQNWFINQFTSQLFLPLNP-GAHKWAMVFMSLMLFLISLNMLGLL---PYTF 93
Cdd:pfam00119   5 LIVALILLLFLLLATRkTKKLVPGRLQNFVEMLVEFVDNIVKDNIGKkKGRKFFPLLLTLFFFILVSNLLGLIpksPGGF 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911965   94 TPTTQLSLNMGLAVPLWLATVIIGMRNQPTIA-LGHLLPEGTPTPLIPVLIIIETISHLMRPLALGVRLTANLTAGHLLI 172
Cdd:pfam00119  85 TVTADINVTLALALIVFLLVHYYGIKKHGLGGyFKKLFVPPVPLPLVPLLLPIEIISEFARPVSLSLRLFGNMLAGHLLL 164


                  ....*..
gi 314911965  173 QLIATAA 179
Cdd:pfam00119 165 LLLAGLI 171
ATP6 MTH00175
ATP synthase F0 subunit 6; Provisional
 74-176 9.80e-19

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177228  Cd Length: 244  Bit Score: 80.44  E-value: 9.80e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911965  74 MSLMLFLISLNMLGLLPYTFTPTTQLSLNMGLAVPLWLATVIIGMRNQPTIALGHLLPEGTPTPLIPVLIIIETISHLMR 153
Cdd:MTH00175  87 LSLFLFIAILNILGLFPYVFTPTAHIIITFGLSLSIIIAVTLLGFLTFKWNFLSILMPGGAPLVLAPFLVLIETLSYLIR 166

                         90       100
                 ....*....|....*....|...
gi 314911965 154 PLALGVRLTANLTAGHLLIQLIA 176
Cdd:MTH00175 167 AISLGVRLAANISAGHLLFAILS 189
AtpB COG0356
FoF1-type ATP synthase, membrane subunit a [Energy production and conversion]; FoF1-type ATP ...
 66-179 6.55e-17

FoF1-type ATP synthase, membrane subunit a [Energy production and conversion]; FoF1-type ATP synthase, membrane subunit a is part of the Pathway/BioSystem: FoF1-type ATP synthase


Pssm-ID: 440125 [Multi-domain]  Cd Length: 212  Bit Score: 74.72  E-value: 6.55e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911965  66 AHKWAMVFMSLMLFLISLNMLGLLPYTFTPTTQLSLNMGLAVPLWLATVIIGMRNQPTIA-LGHLLPEGTPtPLIPVLII 144
Cdd:COG0356   54 GRKFAPLLLTLFLFILVSNLLGLIPGLFPPTADINVTLALALIVFVLVHYYGIKKKGLGGyLKHLFFPPFP-WLAPLMLP 132

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 314911965 145 IETISHLMRPLALGVRLTANLTAGHLLIQLIATAA 179
Cdd:COG0356  133 IEIISELARPLSLSLRLFGNMFAGHIILLLLAGLA 167
PRK05815 PRK05815
F0F1 ATP synthase subunit A; Validated
 67-179 1.05e-14

F0F1 ATP synthase subunit A; Validated


Pssm-ID: 235617  Cd Length: 227  Bit Score: 69.05  E-value: 1.05e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911965  67 HKWAMVFMSLMLFLISLNMLGLLP-YTFTPTTQLSLNMGLAVPLWLATVIIGMRNQptiALGHLLPEGTPTPlIPVLIII 145
Cdd:PRK05815  70 KKFAPLAFTLFLFILLMNLLGLIPyLLFPPTADINVTLALALIVFVLVIYYGIKKK---GLGGYLKEFYLQP-HPLLLPI 145

                         90       100       110
                 ....*....|....*....|....*....|....
gi 314911965 146 ETISHLMRPLALGVRLTANLTAGHLLIQLIATAA 179
Cdd:PRK05815 146 EIISEFSRPISLSLRLFGNMLAGELILALIALLG 179
ATP6 MTH00174
ATP synthase F0 subunit 6; Provisional
 41-179 2.07e-14

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 133799  Cd Length: 252  Bit Score: 68.81  E-value: 2.07e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911965  41 NRLLAMQNWFINQFTSQLFLPLNPGAHKWAMVFMSLMLFLISLNMLGLLPYTFTPTTQLSLNMGLAVPLWLATVIIGMRN 120
Cdd:MTH00174  62 NRILVGLELIYSHFYTVLKDNLGNKGGNYLAFVLSLFILILFGNGLGLFPYVFTPTVHMVITLGLSFAIIVGTTLAGLIT 141

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 314911965 121 QPTIALGHLLPEGTPTPLIPVLIIIETISHLMRPLALGVRLTANLTAGHLLIQLIATAA 179
Cdd:MTH00174 142 FRFNFFSILMPQGAPLALAPLLTIIETLSYISRAISLGVRLAANISSGHLLFSIIASFA 200
ATP6 MTH00087
ATP synthase F0 subunit 6; Provisional
 71-175 8.64e-11

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177152  Cd Length: 195  Bit Score: 58.07  E-value: 8.64e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911965  71 MVFMSLMLFLISLNMLGLLPYTFTPTTQLSLNMGLAVPLWLATVIIGMRNQptIALGHLLPEGTPTPLIP-VLIIIETIS 149
Cdd:MTH00087  53 VISFFTFIVLLLFCFGGLFPYSFSPCGMVEFTFLYALVAWLSTFLSFLSKS--EKFSVYLSKGSDSFLKTfSMLFVEIVS 130

                         90       100
                 ....*....|....*....|....*.
gi 314911965 150 HLMRPLALGVRLTANLTAGHLLIQLI 175
Cdd:MTH00087 131 ELSRPLALTLRLTVNLMVGHLISSLL 156
PRK13419 PRK13419
F0F1 ATP synthase subunit A; Provisional
 64-172 6.45e-10

F0F1 ATP synthase subunit A; Provisional


Pssm-ID: 237381  Cd Length: 342  Bit Score: 56.67  E-value: 6.45e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911965  64 PGAHKWAMVFMSLMLFLISLNMLGLLPYTFTPTTQLSLNMGLAVPLWLATVIIGMRNQPTIALGHLLPEGTPTPLIPVLI 143
Cdd:PRK13419 165 HGYEKFLPYLLTVFFFILVCNLLGLVPYGATATGNINVTLTLAVFTFFITQYAAIKAHGIKGYLAHLTGGTHWSLWIIMI 244

                         90       100
                 ....*....|....*....|....*....
gi 314911965 144 IIETISHLMRPLALGVRLTANLTAGHLLI 172
Cdd:PRK13419 245 PIEFIGLFTKPFALTVRLFANMTAGHIVI 273
PRK13417 PRK13417
F0F1 ATP synthase subunit A; Provisional
 94-172 2.15e-06

F0F1 ATP synthase subunit A; Provisional


Pssm-ID: 237380  Cd Length: 352  Bit Score: 46.42  E-value: 2.15e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911965  94 TPTTQLSLNMGLAVPLWLATVIIGMRNQPTIALGHLLPEGTPTPLIPVLIIIETI-SHLMRPLALGVRLTANLTAGHLLI 172
Cdd:PRK13417 217 TVTGDISVTMTLALLTMFLIYGAGFSYQGPKFIWHSVPNGVPLLLYPIMWPLEFIvSPMAKTFALTVRLLANMTAGHVII 296
ATP6 MTH00050
ATP synthase F0 subunit 6; Validated
 71-168 3.05e-03

ATP synthase F0 subunit 6; Validated


Pssm-ID: 177125  Cd Length: 170  Bit Score: 36.40  E-value: 3.05e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911965  71 MVFMSLMLFLISLNMLGLLPYTFTPTTQLSLNMGLAVPLWLATVIIGMRNQPTIALGHLLPEGTPTPLIPVLIIIETISH 150
Cdd:MTH00050  24 YYYSVVLFIVLFLFLLYRLPYIYSPFLFVVFLFVVVFPLFISLFLSRVFDSLNEFFSSFVPVGTPLYICPFVCIAETISY 103

                         90
                 ....*....|....*...
gi 314911965 151 LMRPLALGVRLTANLTAG 168
Cdd:MTH00050 104 IIRPVVLILRPFINISLG 121
PRK13420 PRK13420
F0F1 ATP synthase subunit A; Provisional
 74-176 4.37e-03

F0F1 ATP synthase subunit A; Provisional


Pssm-ID: 237382 [Multi-domain]  Cd Length: 226  Bit Score: 36.64  E-value: 4.37e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911965  74 MSLMLFLISLNMLGLLPYTFTPTTQLSLNMGLAVPLWLATVIIGMRNQPTIA-LGHLLpegTPTpliPVLIIIETISHLM 152
Cdd:PRK13420  79 GTLWIFILVANLIGLIPGFHSPTADLSVTAALALLVFFSVHWFGIRAEGLREyLKHYL---SPS---PFLLPFHLISEIT 152

                         90       100
                 ....*....|....*....|....*..
gi 314911965 153 RPLALGVRLTAN---LTAGHLLIQLIA 176
Cdd:PRK13420 153 RTLALAVRLFGNimsLELAALLVLLVA 179
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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