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Conserved domains on  [gi|314911973|gb|ADT63732|]
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ATP synthase F0 subunit 6, partial (mitochondrion) [Oreochromis sp. TP]

Protein Classification

ATP synthase F0 subunit 6( domain architecture ID 10009577)

ATP synthase F0 subunit 6 is part of the mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V), which produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ATP6 MTH00132
ATP synthase F0 subunit 6; Provisional
 1-179 8.06e-119

ATP synthase F0 subunit 6; Provisional


:

Pssm-ID: 177190  Cd Length: 227  Bit Score: 335.30  E-value: 8.06e-119
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911973   1 MTLSFFDQFMSPTYLGIPLIALALSLPWILYPKPTTRWLNNRLITLQGWFINRFTQQIFQPLSLGGHKWATLLASLMLFL 80
Cdd:MTH00132   1 MTLSFFDQFMSPTYLGIPLIALALTLPWILFPTPTSRWLNNRLLTLQGWFINRFTQQLLLPLNVGGHKWALLLTSLMLFL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911973  81 ITLNMLGLLPYTFTPTTQLSLNMAFAVPLWLATVIIGMRNQPTHALGHLLPEGTPTLLIPVLIIIETISLFIRPLALGVR 160
Cdd:MTH00132  81 ITLNMLGLLPYTFTPTTQLSLNMGLAVPLWLATVIIGMRNQPTHALGHLLPEGTPTPLIPVLIIIETISLFIRPLALGVR 160

                        170
                 ....*....|....*....
gi 314911973 161 LTANLTAGHLLIQLIATAA 179
Cdd:MTH00132 161 LTANLTAGHLLIQLIATAA 179
 
Name Accession Description Interval E-value
ATP6 MTH00132
ATP synthase F0 subunit 6; Provisional
 1-179 8.06e-119

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177190  Cd Length: 227  Bit Score: 335.30  E-value: 8.06e-119
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911973   1 MTLSFFDQFMSPTYLGIPLIALALSLPWILYPKPTTRWLNNRLITLQGWFINRFTQQIFQPLSLGGHKWATLLASLMLFL 80
Cdd:MTH00132   1 MTLSFFDQFMSPTYLGIPLIALALTLPWILFPTPTSRWLNNRLLTLQGWFINRFTQQLLLPLNVGGHKWALLLTSLMLFL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911973  81 ITLNMLGLLPYTFTPTTQLSLNMAFAVPLWLATVIIGMRNQPTHALGHLLPEGTPTLLIPVLIIIETISLFIRPLALGVR 160
Cdd:MTH00132  81 ITLNMLGLLPYTFTPTTQLSLNMGLAVPLWLATVIIGMRNQPTHALGHLLPEGTPTPLIPVLIIIETISLFIRPLALGVR 160

                        170
                 ....*....|....*....
gi 314911973 161 LTANLTAGHLLIQLIATAA 179
Cdd:MTH00132 161 LTANLTAGHLLIQLIATAA 179
ATP_synt_6_or_A TIGR01131
ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Bacterial forms should be ...
 4-179 2.42e-41

ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Bacterial forms should be designated ATP synthase, F0 subunit A; eukaryotic (chloroplast and mitochondrial) forms should be designated ATP synthase, F0 subunit 6. The F1/F0 ATP synthase is a multisubunit, membrane associated enzyme found in bacteria and mitochondria and chloroplast. This enzyme is principally involved in the synthesis of ATP from ADP and inorganic phosphate by coupling the energy derived from the proton electrochemical gradient across the biological membrane. A brief description of this multisubunit enzyme complex: F1 and F0 represent two major clusters of subunits. Individual subunits in each of these clusters are named differently in prokaryotes and in organelles e.g., mitochondria and chloroplast. The bacterial equivalent of subunit 6 is named subunit 'A'. It has been shown that proton is conducted though this subunit. Typically, deprotonation and reprotonation of the acidic amino acid side-chains are implicated in the process. [Energy metabolism, ATP-proton motive force interconversion]


Pssm-ID: 273458  Cd Length: 226  Bit Score: 138.49  E-value: 2.42e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911973    4 SFFDQFMSPTYLGIPLIALALSLPWILYPKPTTRWL-NNRLITLQGWFINRFTQQIFQPLSLGGHKWATLLASLMLFLIT 82
Cdd:TIGR01131   4 QFDISPITLFSLTLLSLILLLSLLIFLISSSLSRWLiPSRWQNLMESIYEFVLSIVKSQIGGKKGKFFPLIFTLFLFILI 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911973   83 LNMLGLLPYTFTPTTQLSLNMAFAVPLWLATVIIGMRNQPTHALGHLLPEGTPTLLIPVLIIIETISLFIRPLALGVRLT 162
Cdd:TIGR01131  84 SNLLGLIPYSFTPTSHLSFTLGLALPLWLGLTISGFRKHPKGFLAHLVPSGTPLPLIPFLVIIETISYLARPISLSVRLF 163

                         170
                  ....*....|....*..
gi 314911973  163 ANLTAGHLLIQLIATAA 179
Cdd:TIGR01131 164 ANISAGHLLLTLLSGLL 180
ATP-synt_Fo_a_6 cd00310
ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms ...
 66-179 4.75e-32

ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms are designated as ATP synthase, Fo complex, subunit a; eukaryotic (chloroplast and mitochondrial) forms are designated as ATP synthase, Fo complex, subunit 6. The F-ATP synthases (also called FoF1-ATPases) consist of two structural domains: F1 (factor one) complex containing the soluble catalytic core, and Fo (oligomycin sensitive factor) complex containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. F-ATP synthases are primarily found in the inner membranes of eukaryotic mitochondria, in the thylakoid membranes of chloroplasts or in the plasma membranes of bacteria. F-ATP synthase has also been found in the archaea Methanosarcina acetivorans. F-ATP synthases are the primary producers of ATP, using the proton gradient generated by oxidative phosphorylation (mitochondria) or photosynthesis (chloroplasts). Alternatively, under conditions of low driving force, ATP synthases function as ATPases, thus generating a transmembrane proton or Na(+) gradient at the expense of energy derived from ATP hydrolysis.


Pssm-ID: 349411 [Multi-domain]  Cd Length: 156  Bit Score: 112.49  E-value: 4.75e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911973  66 GHKWATLLASLMLFLITLNMLGLLPYTFTPTTQLSLNMAFAVPLWLATVIIGMRNQPTHALGHLLPEGTPTLLIPVLIII 145
Cdd:cd00310    1 GKKYLPLLGTLFLFILFSNLLGLIPYSFTPTSHLNVTLALALIVFLGVHILGIKKHGLGFFLHFLPPGTPLPLAPLMVPI 80

                         90       100       110
                 ....*....|....*....|....*....|....
gi 314911973 146 ETISLFIRPLALGVRLTANLTAGHLLIQLIATAA 179
Cdd:cd00310   81 ELISELIRPLSLSVRLFANMFAGHLLLALLSGLV 114
ATP-synt_A pfam00119
ATP synthase A chain;
19-179 9.61e-25

ATP synthase A chain;


Pssm-ID: 459679 [Multi-domain]  Cd Length: 216  Bit Score: 95.25  E-value: 9.61e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911973   19 LIALALSLPWILYPKPTTRWLNNRLITLQGWFINRFTQQIFQPL-SLGGHKWATLLASLMLFLITLNMLGLL---PYTFT 94
Cdd:pfam00119   6 IVALILLLFLLLATRKTKKLVPGRLQNFVEMLVEFVDNIVKDNIgKKKGRKFFPLLLTLFFFILVSNLLGLIpksPGGFT 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911973   95 PTTQLSLNMAFAVPLWLATVIIGMRNQPTHA-LGHLLPEGTPTLLIPVLIIIETISLFIRPLALGVRLTANLTAGHLLIQ 173
Cdd:pfam00119  86 VTADINVTLALALIVFLLVHYYGIKKHGLGGyFKKLFVPPVPLPLVPLLLPIEIISEFARPVSLSLRLFGNMLAGHLLLL 165


                  ....*.
gi 314911973  174 LIATAA 179
Cdd:pfam00119 166 LLAGLI 171
AtpB COG0356
FoF1-type ATP synthase, membrane subunit a [Energy production and conversion]; FoF1-type ATP ...
 66-179 4.87e-19

FoF1-type ATP synthase, membrane subunit a [Energy production and conversion]; FoF1-type ATP synthase, membrane subunit a is part of the Pathway/BioSystem: FoF1-type ATP synthase


Pssm-ID: 440125 [Multi-domain]  Cd Length: 212  Bit Score: 80.50  E-value: 4.87e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911973  66 GHKWATLLASLMLFLITLNMLGLLPYTFTPTTQLSLNMAFAVPLWLATVIIGMRNQ-PTHALGHLLPEGTPtLLIPVLII 144
Cdd:COG0356   54 GRKFAPLLLTLFLFILVSNLLGLIPGLFPPTADINVTLALALIVFVLVHYYGIKKKgLGGYLKHLFFPPFP-WLAPLMLP 132

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 314911973 145 IETISLFIRPLALGVRLTANLTAGHLLIQLIATAA 179
Cdd:COG0356  133 IEIISELARPLSLSLRLFGNMFAGHIILLLLAGLA 167
 
Name Accession Description Interval E-value
ATP6 MTH00132
ATP synthase F0 subunit 6; Provisional
 1-179 8.06e-119

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177190  Cd Length: 227  Bit Score: 335.30  E-value: 8.06e-119
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911973   1 MTLSFFDQFMSPTYLGIPLIALALSLPWILYPKPTTRWLNNRLITLQGWFINRFTQQIFQPLSLGGHKWATLLASLMLFL 80
Cdd:MTH00132   1 MTLSFFDQFMSPTYLGIPLIALALTLPWILFPTPTSRWLNNRLLTLQGWFINRFTQQLLLPLNVGGHKWALLLTSLMLFL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911973  81 ITLNMLGLLPYTFTPTTQLSLNMAFAVPLWLATVIIGMRNQPTHALGHLLPEGTPTLLIPVLIIIETISLFIRPLALGVR 160
Cdd:MTH00132  81 ITLNMLGLLPYTFTPTTQLSLNMGLAVPLWLATVIIGMRNQPTHALGHLLPEGTPTPLIPVLIIIETISLFIRPLALGVR 160

                        170
                 ....*....|....*....
gi 314911973 161 LTANLTAGHLLIQLIATAA 179
Cdd:MTH00132 161 LTANLTAGHLLIQLIATAA 179
ATP6 MTH00073
ATP synthase F0 subunit 6; Provisional
 1-179 2.11e-96

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177144  Cd Length: 227  Bit Score: 278.39  E-value: 2.11e-96
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911973   1 MTLSFFDQFMSPTYLGIPLIALALSLPWILYPKPTTRWLNNRLITLQGWFINRFTQQIFQPLSLGGHKWATLLASLMLFL 80
Cdd:MTH00073   1 MNLSFFDQFLSPTLLGIPLIMLAMLLPWLLFPTPTNKWLNNRLSTLQIWFLQNFTKQLMLPLNTPGHKWALILTSLMVFL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911973  81 ITLNMLGLLPYTFTPTTQLSLNMAFAVPLWLATVIIGMRNQPTHALGHLLPEGTPTLLIPVLIIIETISLFIRPLALGVR 160
Cdd:MTH00073  81 ITMNLLGLLPYTFTPTTQLSLNLGLAVPLWLATVLIGLRNQPTASLGHLLPEGTPTLLIPILIIIETISLFIRPLALGVR 160

                        170
                 ....*....|....*....
gi 314911973 161 LTANLTAGHLLIQLIATAA 179
Cdd:MTH00073 161 LTANLTAGHLLIQLISTAT 179
ATP6 MTH00120
ATP synthase F0 subunit 6; Provisional
 1-179 4.86e-86

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177181  Cd Length: 227  Bit Score: 252.05  E-value: 4.86e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911973   1 MTLSFFDQFMSPTYLGIPLIALALSLPWILYPKPTTRWLNNRLITLQGWFINRFTQQIFQPLSLGGHKWATLLASLMLFL 80
Cdd:MTH00120   1 MNLNFFDQFSSPELLGIPLILLAMLIPALLIPSPKNRLLTNRLTTLQLWLIKLITKQLMLPLNKKGHKWALILTSLMLLL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911973  81 ITLNMLGLLPYTFTPTTQLSLNMAFAVPLWLATVIIGMRNQPTHALGHLLPEGTPTLLIPVLIIIETISLFIRPLALGVR 160
Cdd:MTH00120  81 LLINLLGLLPYTFTPTTQLSMNMALAIPLWLATVLTGLRNQPTTSLAHLLPEGTPTPLIPALILIETISLLIRPLALGVR 160

                        170
                 ....*....|....*....
gi 314911973 161 LTANLTAGHLLIQLIATAA 179
Cdd:MTH00120 161 LTANLTAGHLLIQLISTAT 179
ATP6 MTH00179
ATP synthase F0 subunit 6; Provisional
 1-179 3.32e-80

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177230  Cd Length: 227  Bit Score: 237.54  E-value: 3.32e-80
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911973   1 MTLSFFDQFMSPTYLGIPLIALALSLPWILYPKPTTRWLNNRLITLQGWFINRFTQQIFQPLSLGGHKWATLLASLMLFL 80
Cdd:MTH00179   1 MMLSMFDQFESPSLLGIPLLALALLLPWLLFPSLTNRWLNNRLSTLQSWFFGSFTFQLMQPINKKGHKWAVLFLSLMLFL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911973  81 ITLNMLGLLPYTFTPTTQLSLNMAFAVPLWLATVIIGMRNQPTHALGHLLPEGTPTLLIPVLIIIETISLFIRPLALGVR 160
Cdd:MTH00179  81 LTLNLLGLLPYTFTPTTQLSLNLGLALPLWLGTVLYGLFNQPTIALAHLLPEGTPTPLIPMLVWIETISLLIRPLALGVR 160

                        170
                 ....*....|....*....
gi 314911973 161 LTANLTAGHLLIQLIATAA 179
Cdd:MTH00179 161 LTANITAGHLLMHLISSAV 179
ATP6 MTH00101
ATP synthase F0 subunit 6; Validated
 1-179 8.11e-61

ATP synthase F0 subunit 6; Validated


Pssm-ID: 177163  Cd Length: 226  Bit Score: 188.24  E-value: 8.11e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911973   1 MTLSFFDQFMSPTYLGIPLIALALSLPWILYPKPTtRWLNNRLITLQGWFINRFTQQIFQPLSLGGHKWATLLASLMLFL 80
Cdd:MTH00101   1 MNENLFASFITPTILGLPIVTLIIMFPSLLFPTPN-RLINNRLISIQQWLIQLTSKQMMTIHNTKGQTWSLMLMSLILFI 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911973  81 ITLNMLGLLPYTFTPTTQLSLNMAFAVPLWLATVIIGMRNQPTHALGHLLPEGTPTLLIPVLIIIETISLFIRPLALGVR 160
Cdd:MTH00101  80 GSTNLLGLLPHSFTPTTQLSMNLGMAIPLWAGTVITGFRNKTKASLAHFLPQGTPTPLIPMLVIIETISLFIQPMALAVR 159

                        170
                 ....*....|....*....
gi 314911973 161 LTANLTAGHLLIQLIATAA 179
Cdd:MTH00101 160 LTANITAGHLLIHLIGGAT 178
ATP_synt_6_or_A TIGR01131
ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Bacterial forms should be ...
 4-179 2.42e-41

ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Bacterial forms should be designated ATP synthase, F0 subunit A; eukaryotic (chloroplast and mitochondrial) forms should be designated ATP synthase, F0 subunit 6. The F1/F0 ATP synthase is a multisubunit, membrane associated enzyme found in bacteria and mitochondria and chloroplast. This enzyme is principally involved in the synthesis of ATP from ADP and inorganic phosphate by coupling the energy derived from the proton electrochemical gradient across the biological membrane. A brief description of this multisubunit enzyme complex: F1 and F0 represent two major clusters of subunits. Individual subunits in each of these clusters are named differently in prokaryotes and in organelles e.g., mitochondria and chloroplast. The bacterial equivalent of subunit 6 is named subunit 'A'. It has been shown that proton is conducted though this subunit. Typically, deprotonation and reprotonation of the acidic amino acid side-chains are implicated in the process. [Energy metabolism, ATP-proton motive force interconversion]


Pssm-ID: 273458  Cd Length: 226  Bit Score: 138.49  E-value: 2.42e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911973    4 SFFDQFMSPTYLGIPLIALALSLPWILYPKPTTRWL-NNRLITLQGWFINRFTQQIFQPLSLGGHKWATLLASLMLFLIT 82
Cdd:TIGR01131   4 QFDISPITLFSLTLLSLILLLSLLIFLISSSLSRWLiPSRWQNLMESIYEFVLSIVKSQIGGKKGKFFPLIFTLFLFILI 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911973   83 LNMLGLLPYTFTPTTQLSLNMAFAVPLWLATVIIGMRNQPTHALGHLLPEGTPTLLIPVLIIIETISLFIRPLALGVRLT 162
Cdd:TIGR01131  84 SNLLGLIPYSFTPTSHLSFTLGLALPLWLGLTISGFRKHPKGFLAHLVPSGTPLPLIPFLVIIETISYLARPISLSVRLF 163

                         170
                  ....*....|....*..
gi 314911973  163 ANLTAGHLLIQLIATAA 179
Cdd:TIGR01131 164 ANISAGHLLLTLLSGLL 180
ATP6 MTH00035
ATP synthase F0 subunit 6; Validated
 4-178 2.49e-41

ATP synthase F0 subunit 6; Validated


Pssm-ID: 177110  Cd Length: 229  Bit Score: 138.57  E-value: 2.49e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911973   4 SFFDQFMSPTYLGIPL--IALALSLPWILYPKPTTrWLNNRLITLQGWFINRFTQQIFQPLSLGGHKWATLLASLMLFLI 81
Cdd:MTH00035   6 SIFGQFSPDTILFIPLtlLSSVIALSWLFFINPTN-WLPSRSQSIWLTFRQEILKLIFQNTNPNTAPWAGLLTTVFILIL 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911973  82 TLNMLGLLPYTFTPTTQLSLNMAFAVPLWLATVIIGMRNQPTHALGHLLPEGTPTLLIPVLIIIETISLFIRPLALGVRL 161
Cdd:MTH00035  85 SINVLGLFPYAFTSTSHISLTYSLGIPLWMSVNILGFYLAFNSRLSHLVPQGTPSFLIPLMVWIETLSLFAQPIALGLRL 164

                        170
                 ....*....|....*..
gi 314911973 162 TANLTAGHLLIQLIATA 178
Cdd:MTH00035 165 AANLTAGHLLIFLLSTA 181
ATP6 MTH00157
ATP synthase F0 subunit 6; Provisional
 72-175 5.00e-34

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 214441  Cd Length: 223  Bit Score: 119.50  E-value: 5.00e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911973  72 LLASLMLFLITLNMLGLLPYTFTPTTQLSLNMAFAVPLWLATVIIGMRNQPTHALGHLLPEGTPTLLIPVLIIIETISLF 151
Cdd:MTH00157  71 IFISLFSFILFNNFLGLFPYIFTSTSHLSLTLSLALPLWLSFMLFGWINNTNHMFAHLVPQGTPPILMPFMVLIETISNL 150

                         90       100
                 ....*....|....*....|....
gi 314911973 152 IRPLALGVRLTANLTAGHLLIQLI 175
Cdd:MTH00157 151 IRPGTLAVRLAANMIAGHLLLTLL 174
ATP6 MTH00173
ATP synthase F0 subunit 6; Provisional
 1-176 1.47e-33

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 214448  Cd Length: 231  Bit Score: 118.81  E-value: 1.47e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911973   1 MTLSFFDQFMSPTYLGIPLIALALSLP-WILYPKPTTRWLN-NRLITLQGWFINRFTQQIFQPLSLGGHKWATLLASLML 78
Cdd:MTH00173   1 MMVDLFSSFDDHNSSFSSLSFLMWLLSlMSLFFFSSSVWVSsSNLSSVFKLFVLTVSSQVTRSSGLNLGGFSLLLSSLFL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911973  79 FLITLNMLGLLPYTFTPTTQLSLNMAFAVPLWLATVIIGMRNQPTHALGHLLPEGTPTLLIPVLIIIETISLFIRPLALG 158
Cdd:MTH00173  81 FLISLNLSGLLPFVFSVTSHLAFTFSLALPLWLSLILSGLFYNPSKSLAGLVPAGAPAGLNPFLVLIETVSILIRPLTLT 160

                        170
                 ....*....|....*...
gi 314911973 159 VRLTANLTAGHLLIQLIA 176
Cdd:MTH00173 161 VRLLANISAGHIVLTLIG 178
ATP6 MTH00176
ATP synthase F0 subunit 6; Provisional
 1-178 3.63e-32

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 214449  Cd Length: 229  Bit Score: 115.13  E-value: 3.63e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911973   1 MTLSFFDQFMSPTYLGIPLIALALSLPWI-LYPKPTTRWL-NNRLITLQGWFINRFTQQIFQPLSLGGHKWATLLASLML 78
Cdd:MTH00176   1 MLVDLFSSFDPPNKNIFSMISLSWITLLLfLLLMPSSVWFcPSKLQVFMLMFSTFLPEMILRSNGSYILGSASIIISLFI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911973  79 FLITLNMLGLLPYTFTPTTQLSLNMAFAVPLWLATVIIGMRNQPTHALGHLLPEGTPTLLIPVLIIIETISLFIRPLALG 158
Cdd:MTH00176  81 LVMSLNLSGLIPYVFTSTSHLVITLSLALPLWLGVILSGFINNFYSRLSHLVPQGTPPLLNPFLVLIELVSLLIRPLTLA 160

                        170       180
                 ....*....|....*....|
gi 314911973 159 VRLTANLTAGHLLIQLIATA 178
Cdd:MTH00176 161 VRLAANLSAGHLLLGLLGAA 180
ATP-synt_Fo_a_6 cd00310
ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms ...
 66-179 4.75e-32

ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms are designated as ATP synthase, Fo complex, subunit a; eukaryotic (chloroplast and mitochondrial) forms are designated as ATP synthase, Fo complex, subunit 6. The F-ATP synthases (also called FoF1-ATPases) consist of two structural domains: F1 (factor one) complex containing the soluble catalytic core, and Fo (oligomycin sensitive factor) complex containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. F-ATP synthases are primarily found in the inner membranes of eukaryotic mitochondria, in the thylakoid membranes of chloroplasts or in the plasma membranes of bacteria. F-ATP synthase has also been found in the archaea Methanosarcina acetivorans. F-ATP synthases are the primary producers of ATP, using the proton gradient generated by oxidative phosphorylation (mitochondria) or photosynthesis (chloroplasts). Alternatively, under conditions of low driving force, ATP synthases function as ATPases, thus generating a transmembrane proton or Na(+) gradient at the expense of energy derived from ATP hydrolysis.


Pssm-ID: 349411 [Multi-domain]  Cd Length: 156  Bit Score: 112.49  E-value: 4.75e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911973  66 GHKWATLLASLMLFLITLNMLGLLPYTFTPTTQLSLNMAFAVPLWLATVIIGMRNQPTHALGHLLPEGTPTLLIPVLIII 145
Cdd:cd00310    1 GKKYLPLLGTLFLFILFSNLLGLIPYSFTPTSHLNVTLALALIVFLGVHILGIKKHGLGFFLHFLPPGTPLPLAPLMVPI 80

                         90       100       110
                 ....*....|....*....|....*....|....
gi 314911973 146 ETISLFIRPLALGVRLTANLTAGHLLIQLIATAA 179
Cdd:cd00310   81 ELISELIRPLSLSVRLFANMFAGHLLLALLSGLV 114
ATP6 MTH00005
ATP synthase F0 subunit 6; Provisional
 4-179 1.62e-25

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 164583  Cd Length: 231  Bit Score: 97.88  E-value: 1.62e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911973   4 SFFDQFMSPTYLGI-PLIALALSLPWILYPKPTTRWLNNRLITLQGWFINRFTQQIFQPLSLGGHKWATLLASLMLFLIT 82
Cdd:MTH00005   7 SSFDPATNSLFNNLsSTAFWAFNFSIILLLSSSFWITPNRLSSIMSPPKSTMHTQLSRTFGKHLKGFSSLISALFTMIIL 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911973  83 LNMLGLLPYTFTPTTQLSLNMAFAVPLWLATVIIGMRNQPTHALGHLLPEGTPTLLIPVLIIIETISLFIRPLALGVRLT 162
Cdd:MTH00005  87 MNLSGLLPYVFSTSSHLIFTLTLGLPLWLSLIMSSVTFSPKKFAAHLLPGGAPDWLNPFLVLIETISILVRPITLSFRLA 166

                        170
                 ....*....|....*..
gi 314911973 163 ANLTAGHLLIQLIATAA 179
Cdd:MTH00005 167 ANMSAGHIVLSLIGIYA 183
ATP-synt_A pfam00119
ATP synthase A chain;
19-179 9.61e-25

ATP synthase A chain;


Pssm-ID: 459679 [Multi-domain]  Cd Length: 216  Bit Score: 95.25  E-value: 9.61e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911973   19 LIALALSLPWILYPKPTTRWLNNRLITLQGWFINRFTQQIFQPL-SLGGHKWATLLASLMLFLITLNMLGLL---PYTFT 94
Cdd:pfam00119   6 IVALILLLFLLLATRKTKKLVPGRLQNFVEMLVEFVDNIVKDNIgKKKGRKFFPLLLTLFFFILVSNLLGLIpksPGGFT 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911973   95 PTTQLSLNMAFAVPLWLATVIIGMRNQPTHA-LGHLLPEGTPTLLIPVLIIIETISLFIRPLALGVRLTANLTAGHLLIQ 173
Cdd:pfam00119  86 VTADINVTLALALIVFLLVHYYGIKKHGLGGyFKKLFVPPVPLPLVPLLLPIEIISEFARPVSLSLRLFGNMLAGHLLLL 165


                  ....*.
gi 314911973  174 LIATAA 179
Cdd:pfam00119 166 LLAGLI 171
ATP6 MTH00172
ATP synthase F0 subunit 6; Provisional
 1-176 1.51e-24

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 214447  Cd Length: 232  Bit Score: 95.49  E-value: 1.51e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911973   1 MTLSFFDQFMSPTYLGI--PLIALALSLPWILYPKPTTRWLNNRLITLQGWFINRFTQQIFQPLSLGGHKWATLLASLML 78
Cdd:MTH00172   1 MSSSYFDQFNIVWLIGLtnSSIMMILVIIVVLLLFKGIKLIPKRWQSIIEIIYNHFHGVVKDNLGNEGLKYFPFIISLFF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911973  79 FLITLNMLGLLPYTFTPTTQLSLNMAFAVPLWLATVIIGMRNQPTHALGHLLPEGTPTLLIPVLIIIETISLFIRPLALG 158
Cdd:MTH00172  81 FIVFLNLLGLFPYVFTPTTHIVVTLGLSFSIIIGVTLAGFWRFKWDFFSILMPSGAPLGLAPLLVLIETVSYISRAISLG 160

                        170
                 ....*....|....*...
gi 314911973 159 VRLTANLTAGHLLIQLIA 176
Cdd:MTH00172 161 VRLAANLSAGHLLFAILA 178
ATP6 MTH00175
ATP synthase F0 subunit 6; Provisional
 66-176 2.35e-19

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177228  Cd Length: 244  Bit Score: 81.98  E-value: 2.35e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911973  66 GHKWATLLASLMLFLITLNMLGLLPYTFTPTTQLSLNMAFAVPLWLATVIIGMRNQPTHALGHLLPEGTPTLLIPVLIII 145
Cdd:MTH00175  79 GQKYFPFILSLFLFIAILNILGLFPYVFTPTAHIIITFGLSLSIIIAVTLLGFLTFKWNFLSILMPGGAPLVLAPFLVLI 158

                         90       100       110
                 ....*....|....*....|....*....|.
gi 314911973 146 ETISLFIRPLALGVRLTANLTAGHLLIQLIA 176
Cdd:MTH00175 159 ETLSYLIRAISLGVRLAANISAGHLLFAILS 189
AtpB COG0356
FoF1-type ATP synthase, membrane subunit a [Energy production and conversion]; FoF1-type ATP ...
 66-179 4.87e-19

FoF1-type ATP synthase, membrane subunit a [Energy production and conversion]; FoF1-type ATP synthase, membrane subunit a is part of the Pathway/BioSystem: FoF1-type ATP synthase


Pssm-ID: 440125 [Multi-domain]  Cd Length: 212  Bit Score: 80.50  E-value: 4.87e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911973  66 GHKWATLLASLMLFLITLNMLGLLPYTFTPTTQLSLNMAFAVPLWLATVIIGMRNQ-PTHALGHLLPEGTPtLLIPVLII 144
Cdd:COG0356   54 GRKFAPLLLTLFLFILVSNLLGLIPGLFPPTADINVTLALALIVFVLVHYYGIKKKgLGGYLKHLFFPPFP-WLAPLMLP 132

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 314911973 145 IETISLFIRPLALGVRLTANLTAGHLLIQLIATAA 179
Cdd:COG0356  133 IEIISELARPLSLSLRLFGNMFAGHIILLLLAGLA 167
PRK05815 PRK05815
F0F1 ATP synthase subunit A; Validated
 66-179 1.63e-15

F0F1 ATP synthase subunit A; Validated


Pssm-ID: 235617  Cd Length: 227  Bit Score: 71.36  E-value: 1.63e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911973  66 GHKWATLLASLMLFLITLNMLGLLP-YTFTPTTQLSLNMAFAVPLWLATVIIGMRNqptHALGHLLPEGTPTLlIPVLII 144
Cdd:PRK05815  69 GKKFAPLAFTLFLFILLMNLLGLIPyLLFPPTADINVTLALALIVFVLVIYYGIKK---KGLGGYLKEFYLQP-HPLLLP 144

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 314911973 145 IETISLFIRPLALGVRLTANLTAGHLLIQLIATAA 179
Cdd:PRK05815 145 IEIISEFSRPISLSLRLFGNMLAGELILALIALLG 179
ATP6 MTH00174
ATP synthase F0 subunit 6; Provisional
 41-179 2.00e-13

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 133799  Cd Length: 252  Bit Score: 66.12  E-value: 2.00e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911973  41 NRLITLQGWFINRFTQQIFQPLSLGGHKWATLLASLMLFLITLNMLGLLPYTFTPTTQLSLNMAFAVPLWLATVIIGMRN 120
Cdd:MTH00174  62 NRILVGLELIYSHFYTVLKDNLGNKGGNYLAFVLSLFILILFGNGLGLFPYVFTPTVHMVITLGLSFAIIVGTTLAGLIT 141

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 314911973 121 QPTHALGHLLPEGTPTLLIPVLIIIETISLFIRPLALGVRLTANLTAGHLLIQLIATAA 179
Cdd:MTH00174 142 FRFNFFSILMPQGAPLALAPLLTIIETLSYISRAISLGVRLAANISSGHLLFSIIASFA 200
PRK13419 PRK13419
F0F1 ATP synthase subunit A; Provisional
 73-172 1.62e-12

F0F1 ATP synthase subunit A; Provisional


Pssm-ID: 237381  Cd Length: 342  Bit Score: 64.38  E-value: 1.62e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911973  73 LASLMLFLITLNMLGLLPYTFTPTTQLSLNMAFAVPLWLATVIIGMRNQPTHALGHLLPEGTPTLLIPVLIIIETISLFI 152
Cdd:PRK13419 174 LLTVFFFILVCNLLGLVPYGATATGNINVTLTLAVFTFFITQYAAIKAHGIKGYLAHLTGGTHWSLWIIMIPIEFIGLFT 253

                         90       100
                 ....*....|....*....|
gi 314911973 153 RPLALGVRLTANLTAGHLLI 172
Cdd:PRK13419 254 KPFALTVRLFANMTAGHIVI 273
ATP6 MTH00087
ATP synthase F0 subunit 6; Provisional
 75-175 3.49e-11

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177152  Cd Length: 195  Bit Score: 59.22  E-value: 3.49e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911973  75 SLMLFLITLNMLGLLPYTFTPTTQLSLNMAFAVPLWLATVIIGMRNQptHALGHLLPEGTPTLLIP-VLIIIETISLFIR 153
Cdd:MTH00087  57 FTFIVLLLFCFGGLFPYSFSPCGMVEFTFLYALVAWLSTFLSFLSKS--EKFSVYLSKGSDSFLKTfSMLFVEIVSELSR 134

                         90       100
                 ....*....|....*....|..
gi 314911973 154 PLALGVRLTANLTAGHLLIQLI 175
Cdd:MTH00087 135 PLALTLRLTVNLMVGHLISSLL 156
PRK13417 PRK13417
F0F1 ATP synthase subunit A; Provisional
 94-172 5.14e-05

F0F1 ATP synthase subunit A; Provisional


Pssm-ID: 237380  Cd Length: 352  Bit Score: 42.57  E-value: 5.14e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911973  94 TPTTQLSLNMAFAVPLWLATVIIGMRNQPTHALGHLLPEGTPTLLIPVLIIIETI-SLFIRPLALGVRLTANLTAGHLLI 172
Cdd:PRK13417 217 TVTGDISVTMTLALLTMFLIYGAGFSYQGPKFIWHSVPNGVPLLLYPIMWPLEFIvSPMAKTFALTVRLLANMTAGHVII 296
PRK13421 PRK13421
F0F1 ATP synthase subunit A; Provisional
 56-179 6.86e-05

F0F1 ATP synthase subunit A; Provisional


Pssm-ID: 237383  Cd Length: 223  Bit Score: 41.60  E-value: 6.86e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911973  56 QQIFQPLSLGGHKWATLLASLMLFLITLNMLGLLPYTFTPTTQLSLNMAFAVPLWLATVIIGMRNQptHALGHLLPEGTP 135
Cdd:PRK13421  64 AQIRDTMQTDPAPYRALIGTLFLFVLVANWSSLVPGVEPPTAHLETDAALALIVFLATIYYGVRAR--GVRGYLATFAEP 141

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 314911973 136 TLLIPVLIIIETISlfiRPLALGVRLTANLTAGHLLIQLIATAA 179
Cdd:PRK13421 142 TWVMIPLNLVEQLT---RTFSLIVRLFGNVMSGVFVIGIVLSLA 182
PRK13420 PRK13420
F0F1 ATP synthase subunit A; Provisional
 72-176 7.51e-04

F0F1 ATP synthase subunit A; Provisional


Pssm-ID: 237382 [Multi-domain]  Cd Length: 226  Bit Score: 38.57  E-value: 7.51e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911973  72 LLASLMLFLITLNMLGLLPYTFTPTTQLSLNMAFAVPLWLATVIIGMRNQPTHA-LGHLLpegTPTlliPVLIIIETISL 150
Cdd:PRK13420  77 FVGTLWIFILVANLIGLIPGFHSPTADLSVTAALALLVFFSVHWFGIRAEGLREyLKHYL---SPS---PFLLPFHLISE 150

                         90       100
                 ....*....|....*....|....*....
gi 314911973 151 FIRPLALGVRLTAN---LTAGHLLIQLIA 176
Cdd:PRK13420 151 ITRTLALAVRLFGNimsLELAALLVLLVA 179
ATP6 MTH00050
ATP synthase F0 subunit 6; Validated
 75-168 4.30e-03

ATP synthase F0 subunit 6; Validated


Pssm-ID: 177125  Cd Length: 170  Bit Score: 36.02  E-value: 4.30e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911973  75 SLMLFLITLNMLGLLPYTFTPTTQLSLNMAFAVPLWLATVIIGMRNQPTHALGHLLPEGTPTLLIPVLIIIETISLFIRP 154
Cdd:MTH00050  28 VVLFIVLFLFLLYRLPYIYSPFLFVVFLFVVVFPLFISLFLSRVFDSLNEFFSSFVPVGTPLYICPFVCIAETISYIIRP 107

                         90
                 ....*....|....
gi 314911973 155 LALGVRLTANLTAG 168
Cdd:MTH00050 108 VVLILRPFINISLG 121
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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