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Conserved domains on  [gi|314911987|gb|ADT63739|]
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ATP synthase F0 subunit 6, partial (mitochondrion) [Retropinna semoni]

Protein Classification

ATP synthase F0 subunit 6( domain architecture ID 10009577)

ATP synthase F0 subunit 6 is part of the mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V), which produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ATP6 MTH00132
ATP synthase F0 subunit 6; Provisional
 1-179 3.10e-106

ATP synthase F0 subunit 6; Provisional


:

Pssm-ID: 177190  Cd Length: 227  Bit Score: 303.33  E-value: 3.10e-106
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911987   1 MTLSFFDQFMSPTLFGIPLIALALFLPWILFPTPSSRWLNNRLLGLQSWSINRFTQQLLLPLNLGGHKWAVILTSLMLFL 80
Cdd:MTH00132   1 MTLSFFDQFMSPTYLGIPLIALALTLPWILFPTPTSRWLNNRLLTLQGWFINRFTQQLLLPLNVGGHKWALLLTSLMLFL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911987  81 ITINMLGLLPYTYTPTTQLSLNLGLAVPLWLATVIIGLRNQPTAALGHLLPEGTPVPLIPILIIIETISLFIRPLALGVR 160
Cdd:MTH00132  81 ITLNMLGLLPYTFTPTTQLSLNMGLAVPLWLATVIIGMRNQPTHALGHLLPEGTPTPLIPVLIIIETISLFIRPLALGVR 160

                        170
                 ....*....|....*....
gi 314911987 161 LTANLTAGHLLIQLIATAA 179
Cdd:MTH00132 161 LTANLTAGHLLIQLIATAA 179
 
Name Accession Description Interval E-value
ATP6 MTH00132
ATP synthase F0 subunit 6; Provisional
 1-179 3.10e-106

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177190  Cd Length: 227  Bit Score: 303.33  E-value: 3.10e-106
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911987   1 MTLSFFDQFMSPTLFGIPLIALALFLPWILFPTPSSRWLNNRLLGLQSWSINRFTQQLLLPLNLGGHKWAVILTSLMLFL 80
Cdd:MTH00132   1 MTLSFFDQFMSPTYLGIPLIALALTLPWILFPTPTSRWLNNRLLTLQGWFINRFTQQLLLPLNVGGHKWALLLTSLMLFL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911987  81 ITINMLGLLPYTYTPTTQLSLNLGLAVPLWLATVIIGLRNQPTAALGHLLPEGTPVPLIPILIIIETISLFIRPLALGVR 160
Cdd:MTH00132  81 ITLNMLGLLPYTFTPTTQLSLNMGLAVPLWLATVIIGMRNQPTHALGHLLPEGTPTPLIPVLIIIETISLFIRPLALGVR 160

                        170
                 ....*....|....*....
gi 314911987 161 LTANLTAGHLLIQLIATAA 179
Cdd:MTH00132 161 LTANLTAGHLLIQLIATAA 179
ATP_synt_6_or_A TIGR01131
ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Bacterial forms should be ...
 6-179 6.00e-37

ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Bacterial forms should be designated ATP synthase, F0 subunit A; eukaryotic (chloroplast and mitochondrial) forms should be designated ATP synthase, F0 subunit 6. The F1/F0 ATP synthase is a multisubunit, membrane associated enzyme found in bacteria and mitochondria and chloroplast. This enzyme is principally involved in the synthesis of ATP from ADP and inorganic phosphate by coupling the energy derived from the proton electrochemical gradient across the biological membrane. A brief description of this multisubunit enzyme complex: F1 and F0 represent two major clusters of subunits. Individual subunits in each of these clusters are named differently in prokaryotes and in organelles e.g., mitochondria and chloroplast. The bacterial equivalent of subunit 6 is named subunit 'A'. It has been shown that proton is conducted though this subunit. Typically, deprotonation and reprotonation of the acidic amino acid side-chains are implicated in the process. [Energy metabolism, ATP-proton motive force interconversion]


Pssm-ID: 273458  Cd Length: 226  Bit Score: 127.32  E-value: 6.00e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911987    6 FDQFMSP--TLFGIPLIALALFLPWILFPTPSS---RWLNNRLLGLQSWSINRFTQQLLLPLNLGGHKWAVILTSLMLFL 80
Cdd:TIGR01131   2 FSQFDISpiTLFSLTLLSLILLLSLLIFLISSSlsrWLIPSRWQNLMESIYEFVLSIVKSQIGGKKGKFFPLIFTLFLFI 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911987   81 ITINMLGLLPYTYTPTTQLSLNLGLAVPLWLATVIIGLRNQPTAALGHLLPEGTPVPLIPILIIIETISLFIRPLALGVR 160
Cdd:TIGR01131  82 LISNLLGLIPYSFTPTSHLSFTLGLALPLWLGLTISGFRKHPKGFLAHLVPSGTPLPLIPFLVIIETISYLARPISLSVR 161

                         170
                  ....*....|....*....
gi 314911987  161 LTANLTAGHLLIQLIATAA 179
Cdd:TIGR01131 162 LFANISAGHLLLTLLSGLL 180
ATP-synt_Fo_a_6 cd00310
ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms ...
 66-179 6.58e-27

ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms are designated as ATP synthase, Fo complex, subunit a; eukaryotic (chloroplast and mitochondrial) forms are designated as ATP synthase, Fo complex, subunit 6. The F-ATP synthases (also called FoF1-ATPases) consist of two structural domains: F1 (factor one) complex containing the soluble catalytic core, and Fo (oligomycin sensitive factor) complex containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. F-ATP synthases are primarily found in the inner membranes of eukaryotic mitochondria, in the thylakoid membranes of chloroplasts or in the plasma membranes of bacteria. F-ATP synthase has also been found in the archaea Methanosarcina acetivorans. F-ATP synthases are the primary producers of ATP, using the proton gradient generated by oxidative phosphorylation (mitochondria) or photosynthesis (chloroplasts). Alternatively, under conditions of low driving force, ATP synthases function as ATPases, thus generating a transmembrane proton or Na(+) gradient at the expense of energy derived from ATP hydrolysis.


Pssm-ID: 349411 [Multi-domain]  Cd Length: 156  Bit Score: 99.40  E-value: 6.58e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911987  66 GHKWAVILTSLMLFLITINMLGLLPYTYTPTTQLSLNLGLAVPLWLATVIIGLRNQPTAALGHLLPEGTPVPLIPILIII 145
Cdd:cd00310    1 GKKYLPLLGTLFLFILFSNLLGLIPYSFTPTSHLNVTLALALIVFLGVHILGIKKHGLGFFLHFLPPGTPLPLAPLMVPI 80

                         90       100       110
                 ....*....|....*....|....*....|....
gi 314911987 146 ETISLFIRPLALGVRLTANLTAGHLLIQLIATAA 179
Cdd:cd00310   81 ELISELIRPLSLSVRLFANMFAGHLLLALLSGLV 114
ATP-synt_A pfam00119
ATP synthase A chain;
65-179 2.70e-19

ATP synthase A chain;


Pssm-ID: 459679 [Multi-domain]  Cd Length: 216  Bit Score: 81.00  E-value: 2.70e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911987   65 GGHKWAVILTSLMLFLITINMLGLL---PYTYTPTTQLSLNLGLAVPLWLATVIIGLRNQPTAA-LGHLLPEGTPVPLIP 140
Cdd:pfam00119  53 KGRKFFPLLLTLFFFILVSNLLGLIpksPGGFTVTADINVTLALALIVFLLVHYYGIKKHGLGGyFKKLFVPPVPLPLVP 132

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 314911987  141 ILIIIETISLFIRPLALGVRLTANLTAGHLLIQLIATAA 179
Cdd:pfam00119 133 LLLPIEIISEFARPVSLSLRLFGNMLAGHLLLLLLAGLI 171
AtpB COG0356
FoF1-type ATP synthase, membrane subunit a [Energy production and conversion]; FoF1-type ATP ...
 66-179 3.60e-14

FoF1-type ATP synthase, membrane subunit a [Energy production and conversion]; FoF1-type ATP synthase, membrane subunit a is part of the Pathway/BioSystem: FoF1-type ATP synthase


Pssm-ID: 440125 [Multi-domain]  Cd Length: 212  Bit Score: 67.41  E-value: 3.60e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911987  66 GHKWAVILTSLMLFLITINMLGLLPYTYTPTTQLSLNLGLAVPLWLATVIIGLRNQPTAA-LGHLLPEGTPVPLIPILII 144
Cdd:COG0356   54 GRKFAPLLLTLFLFILVSNLLGLIPGLFPPTADINVTLALALIVFVLVHYYGIKKKGLGGyLKHLFFPPFPWLAPLMLPI 133

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 314911987 145 iETISLFIRPLALGVRLTANLTAGHLLIQLIATAA 179
Cdd:COG0356  134 -EIISELARPLSLSLRLFGNMFAGHIILLLLAGLA 167
 
Name Accession Description Interval E-value
ATP6 MTH00132
ATP synthase F0 subunit 6; Provisional
 1-179 3.10e-106

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177190  Cd Length: 227  Bit Score: 303.33  E-value: 3.10e-106
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911987   1 MTLSFFDQFMSPTLFGIPLIALALFLPWILFPTPSSRWLNNRLLGLQSWSINRFTQQLLLPLNLGGHKWAVILTSLMLFL 80
Cdd:MTH00132   1 MTLSFFDQFMSPTYLGIPLIALALTLPWILFPTPTSRWLNNRLLTLQGWFINRFTQQLLLPLNVGGHKWALLLTSLMLFL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911987  81 ITINMLGLLPYTYTPTTQLSLNLGLAVPLWLATVIIGLRNQPTAALGHLLPEGTPVPLIPILIIIETISLFIRPLALGVR 160
Cdd:MTH00132  81 ITLNMLGLLPYTFTPTTQLSLNMGLAVPLWLATVIIGMRNQPTHALGHLLPEGTPTPLIPVLIIIETISLFIRPLALGVR 160

                        170
                 ....*....|....*....
gi 314911987 161 LTANLTAGHLLIQLIATAA 179
Cdd:MTH00132 161 LTANLTAGHLLIQLIATAA 179
ATP6 MTH00073
ATP synthase F0 subunit 6; Provisional
 1-179 3.32e-91

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177144  Cd Length: 227  Bit Score: 265.29  E-value: 3.32e-91
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911987   1 MTLSFFDQFMSPTLFGIPLIALALFLPWILFPTPSSRWLNNRLLGLQSWSINRFTQQLLLPLNLGGHKWAVILTSLMLFL 80
Cdd:MTH00073   1 MNLSFFDQFLSPTLLGIPLIMLAMLLPWLLFPTPTNKWLNNRLSTLQIWFLQNFTKQLMLPLNTPGHKWALILTSLMVFL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911987  81 ITINMLGLLPYTYTPTTQLSLNLGLAVPLWLATVIIGLRNQPTAALGHLLPEGTPVPLIPILIIIETISLFIRPLALGVR 160
Cdd:MTH00073  81 ITMNLLGLLPYTFTPTTQLSLNLGLAVPLWLATVLIGLRNQPTASLGHLLPEGTPTLLIPILIIIETISLFIRPLALGVR 160

                        170
                 ....*....|....*....
gi 314911987 161 LTANLTAGHLLIQLIATAA 179
Cdd:MTH00073 161 LTANLTAGHLLIQLISTAT 179
ATP6 MTH00120
ATP synthase F0 subunit 6; Provisional
 1-179 6.04e-80

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177181  Cd Length: 227  Bit Score: 236.64  E-value: 6.04e-80
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911987   1 MTLSFFDQFMSPTLFGIPLIALALFLPWILFPTPSSRWLNNRLLGLQSWSINRFTQQLLLPLNLGGHKWAVILTSLMLFL 80
Cdd:MTH00120   1 MNLNFFDQFSSPELLGIPLILLAMLIPALLIPSPKNRLLTNRLTTLQLWLIKLITKQLMLPLNKKGHKWALILTSLMLLL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911987  81 ITINMLGLLPYTYTPTTQLSLNLGLAVPLWLATVIIGLRNQPTAALGHLLPEGTPVPLIPILIIIETISLFIRPLALGVR 160
Cdd:MTH00120  81 LLINLLGLLPYTFTPTTQLSMNMALAIPLWLATVLTGLRNQPTTSLAHLLPEGTPTPLIPALILIETISLLIRPLALGVR 160

                        170
                 ....*....|....*....
gi 314911987 161 LTANLTAGHLLIQLIATAA 179
Cdd:MTH00120 161 LTANLTAGHLLIQLISTAT 179
ATP6 MTH00179
ATP synthase F0 subunit 6; Provisional
 1-179 2.53e-73

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177230  Cd Length: 227  Bit Score: 220.20  E-value: 2.53e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911987   1 MTLSFFDQFMSPTLFGIPLIALALFLPWILFPTPSSRWLNNRLLGLQSWSINRFTQQLLLPLNLGGHKWAVILTSLMLFL 80
Cdd:MTH00179   1 MMLSMFDQFESPSLLGIPLLALALLLPWLLFPSLTNRWLNNRLSTLQSWFFGSFTFQLMQPINKKGHKWAVLFLSLMLFL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911987  81 ITINMLGLLPYTYTPTTQLSLNLGLAVPLWLATVIIGLRNQPTAALGHLLPEGTPVPLIPILIIIETISLFIRPLALGVR 160
Cdd:MTH00179  81 LTLNLLGLLPYTFTPTTQLSLNLGLALPLWLGTVLYGLFNQPTIALAHLLPEGTPTPLIPMLVWIETISLLIRPLALGVR 160

                        170
                 ....*....|....*....
gi 314911987 161 LTANLTAGHLLIQLIATAA 179
Cdd:MTH00179 161 LTANITAGHLLMHLISSAV 179
ATP6 MTH00101
ATP synthase F0 subunit 6; Validated
 1-179 9.96e-58

ATP synthase F0 subunit 6; Validated


Pssm-ID: 177163  Cd Length: 226  Bit Score: 180.53  E-value: 9.96e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911987   1 MTLSFFDQFMSPTLFGIPLIALALFLPWILFPTPSsRWLNNRLLGLQSWSINRFTQQLLLPLNLGGHKWAVILTSLMLFL 80
Cdd:MTH00101   1 MNENLFASFITPTILGLPIVTLIIMFPSLLFPTPN-RLINNRLISIQQWLIQLTSKQMMTIHNTKGQTWSLMLMSLILFI 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911987  81 ITINMLGLLPYTYTPTTQLSLNLGLAVPLWLATVIIGLRNQPTAALGHLLPEGTPVPLIPILIIIETISLFIRPLALGVR 160
Cdd:MTH00101  80 GSTNLLGLLPHSFTPTTQLSMNLGMAIPLWAGTVITGFRNKTKASLAHFLPQGTPTPLIPMLVIIETISLFIQPMALAVR 159

                        170
                 ....*....|....*....
gi 314911987 161 LTANLTAGHLLIQLIATAA 179
Cdd:MTH00101 160 LTANITAGHLLIHLIGGAT 178
ATP_synt_6_or_A TIGR01131
ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Bacterial forms should be ...
 6-179 6.00e-37

ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Bacterial forms should be designated ATP synthase, F0 subunit A; eukaryotic (chloroplast and mitochondrial) forms should be designated ATP synthase, F0 subunit 6. The F1/F0 ATP synthase is a multisubunit, membrane associated enzyme found in bacteria and mitochondria and chloroplast. This enzyme is principally involved in the synthesis of ATP from ADP and inorganic phosphate by coupling the energy derived from the proton electrochemical gradient across the biological membrane. A brief description of this multisubunit enzyme complex: F1 and F0 represent two major clusters of subunits. Individual subunits in each of these clusters are named differently in prokaryotes and in organelles e.g., mitochondria and chloroplast. The bacterial equivalent of subunit 6 is named subunit 'A'. It has been shown that proton is conducted though this subunit. Typically, deprotonation and reprotonation of the acidic amino acid side-chains are implicated in the process. [Energy metabolism, ATP-proton motive force interconversion]


Pssm-ID: 273458  Cd Length: 226  Bit Score: 127.32  E-value: 6.00e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911987    6 FDQFMSP--TLFGIPLIALALFLPWILFPTPSS---RWLNNRLLGLQSWSINRFTQQLLLPLNLGGHKWAVILTSLMLFL 80
Cdd:TIGR01131   2 FSQFDISpiTLFSLTLLSLILLLSLLIFLISSSlsrWLIPSRWQNLMESIYEFVLSIVKSQIGGKKGKFFPLIFTLFLFI 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911987   81 ITINMLGLLPYTYTPTTQLSLNLGLAVPLWLATVIIGLRNQPTAALGHLLPEGTPVPLIPILIIIETISLFIRPLALGVR 160
Cdd:TIGR01131  82 LISNLLGLIPYSFTPTSHLSFTLGLALPLWLGLTISGFRKHPKGFLAHLVPSGTPLPLIPFLVIIETISYLARPISLSVR 161

                         170
                  ....*....|....*....
gi 314911987  161 LTANLTAGHLLIQLIATAA 179
Cdd:TIGR01131 162 LFANISAGHLLLTLLSGLL 180
ATP6 MTH00035
ATP synthase F0 subunit 6; Validated
 4-178 2.88e-35

ATP synthase F0 subunit 6; Validated


Pssm-ID: 177110  Cd Length: 229  Bit Score: 123.16  E-value: 2.88e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911987   4 SFFDQFMSPTLFGIPLIALALF--LPWILFPTPSSrWLNNRLLGLQSWSINRFTQQLLLPLNLGGHKWAVILTSLMLFLI 81
Cdd:MTH00035   6 SIFGQFSPDTILFIPLTLLSSViaLSWLFFINPTN-WLPSRSQSIWLTFRQEILKLIFQNTNPNTAPWAGLLTTVFILIL 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911987  82 TINMLGLLPYTYTPTTQLSLNLGLAVPLWLATVIIGLRNQPTAALGHLLPEGTPVPLIPILIIIETISLFIRPLALGVRL 161
Cdd:MTH00035  85 SINVLGLFPYAFTSTSHISLTYSLGIPLWMSVNILGFYLAFNSRLSHLVPQGTPSFLIPLMVWIETLSLFAQPIALGLRL 164

                        170
                 ....*....|....*..
gi 314911987 162 TANLTAGHLLIQLIATA 178
Cdd:MTH00035 165 AANLTAGHLLIFLLSTA 181
ATP6 MTH00157
ATP synthase F0 subunit 6; Provisional
 1-175 1.79e-28

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 214441  Cd Length: 223  Bit Score: 105.25  E-value: 1.79e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911987   1 MTLSFFDQFMSPTLFGIPLIALALFLPWILFPtpSSRWL-NNRLLGLQSWSINRFTQQLLLPLNLGGHKWAVILTSLMLF 79
Cdd:MTH00157   1 MMTNLFSIFDPSTSFNLSLNWLSTFLGLLFIP--SSFWLiPSRYNILWNKILKTLHKEFKTLLGPKNKGSTLIFISLFSF 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911987  80 LITINMLGLLPYTYTPTTQLSLNLGLAVPLWLATVIIGLRNQPTAALGHLLPEGTPVPLIPILIIIETISLFIRPLALGV 159
Cdd:MTH00157  79 ILFNNFLGLFPYIFTSTSHLSLTLSLALPLWLSFMLFGWINNTNHMFAHLVPQGTPPILMPFMVLIETISNLIRPGTLAV 158

                        170
                 ....*....|....*.
gi 314911987 160 RLTANLTAGHLLIQLI 175
Cdd:MTH00157 159 RLAANMIAGHLLLTLL 174
ATP6 MTH00173
ATP synthase F0 subunit 6; Provisional
 4-176 6.23e-28

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 214448  Cd Length: 231  Bit Score: 104.18  E-value: 6.23e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911987   4 SFFDQFMSPTLFGIPLIALALFLPWILFPTPSSrWLNNRLLGLQSWSINRFTQQLLLPLNLGGHKWAVILTSLMLFLITI 83
Cdd:MTH00173   7 SSFDDHNSSFSSLSFLMWLLSLMSLFFFSSSVW-VSSSNLSSVFKLFVLTVSSQVTRSSGLNLGGFSLLLSSLFLFLISL 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911987  84 NMLGLLPYTYTPTTQLSLNLGLAVPLWLATVIIGLRNQPTAALGHLLPEGTPVPLIPILIIIETISLFIRPLALGVRLTA 163
Cdd:MTH00173  86 NLSGLLPFVFSVTSHLAFTFSLALPLWLSLILSGLFYNPSKSLAGLVPAGAPAGLNPFLVLIETVSILIRPLTLTVRLLA 165

                        170
                 ....*....|...
gi 314911987 164 NLTAGHLLIQLIA 176
Cdd:MTH00173 166 NISAGHIVLTLIG 178
ATP-synt_Fo_a_6 cd00310
ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms ...
 66-179 6.58e-27

ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms are designated as ATP synthase, Fo complex, subunit a; eukaryotic (chloroplast and mitochondrial) forms are designated as ATP synthase, Fo complex, subunit 6. The F-ATP synthases (also called FoF1-ATPases) consist of two structural domains: F1 (factor one) complex containing the soluble catalytic core, and Fo (oligomycin sensitive factor) complex containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. F-ATP synthases are primarily found in the inner membranes of eukaryotic mitochondria, in the thylakoid membranes of chloroplasts or in the plasma membranes of bacteria. F-ATP synthase has also been found in the archaea Methanosarcina acetivorans. F-ATP synthases are the primary producers of ATP, using the proton gradient generated by oxidative phosphorylation (mitochondria) or photosynthesis (chloroplasts). Alternatively, under conditions of low driving force, ATP synthases function as ATPases, thus generating a transmembrane proton or Na(+) gradient at the expense of energy derived from ATP hydrolysis.


Pssm-ID: 349411 [Multi-domain]  Cd Length: 156  Bit Score: 99.40  E-value: 6.58e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911987  66 GHKWAVILTSLMLFLITINMLGLLPYTYTPTTQLSLNLGLAVPLWLATVIIGLRNQPTAALGHLLPEGTPVPLIPILIII 145
Cdd:cd00310    1 GKKYLPLLGTLFLFILFSNLLGLIPYSFTPTSHLNVTLALALIVFLGVHILGIKKHGLGFFLHFLPPGTPLPLAPLMVPI 80

                         90       100       110
                 ....*....|....*....|....*....|....
gi 314911987 146 ETISLFIRPLALGVRLTANLTAGHLLIQLIATAA 179
Cdd:cd00310   81 ELISELIRPLSLSVRLFANMFAGHLLLALLSGLV 114
ATP6 MTH00176
ATP synthase F0 subunit 6; Provisional
 1-178 2.10e-26

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 214449  Cd Length: 229  Bit Score: 100.11  E-value: 2.10e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911987   1 MTLSFFDQFMSPTLFGIPLIALALFLPWI-LFPTPSSRWL--NNRLLGLQSWSiNRFTQQLLLPLNLGGHKWAVILTSLM 77
Cdd:MTH00176   1 MLVDLFSSFDPPNKNIFSMISLSWITLLLfLLLMPSSVWFcpSKLQVFMLMFS-TFLPEMILRSNGSYILGSASIIISLF 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911987  78 LFLITINMLGLLPYTYTPTTQLSLNLGLAVPLWLATVIIGLRNQPTAALGHLLPEGTPVPLIPILIIIETISLFIRPLAL 157
Cdd:MTH00176  80 ILVMSLNLSGLIPYVFTSTSHLVITLSLALPLWLGVILSGFINNFYSRLSHLVPQGTPPLLNPFLVLIELVSLLIRPLTL 159

                        170       180
                 ....*....|....*....|.
gi 314911987 158 GVRLTANLTAGHLLIQLIATA 178
Cdd:MTH00176 160 AVRLAANLSAGHLLLGLLGAA 180
ATP6 MTH00005
ATP synthase F0 subunit 6; Provisional
 4-179 4.75e-23

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 164583  Cd Length: 231  Bit Score: 91.33  E-value: 4.75e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911987   4 SFFDQFMSPTLFGIPLIALALFLPWILFPTPSSRWL-NNRLLGLQSWSINRFTQQLLLPLNLGGHKWAVILTSLMLFLIT 82
Cdd:MTH00005   7 SSFDPATNSLFNNLSSTAFWAFNFSIILLLSSSFWItPNRLSSIMSPPKSTMHTQLSRTFGKHLKGFSSLISALFTMIIL 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911987  83 INMLGLLPYTYTPTTQLSLNLGLAVPLWLATVIIGLRNQPTAALGHLLPEGTPVPLIPILIIIETISLFIRPLALGVRLT 162
Cdd:MTH00005  87 MNLSGLLPYVFSTSSHLIFTLTLGLPLWLSLIMSSVTFSPKKFAAHLLPGGAPDWLNPFLVLIETISILVRPITLSFRLA 166

                        170
                 ....*....|....*..
gi 314911987 163 ANLTAGHLLIQLIATAA 179
Cdd:MTH00005 167 ANMSAGHIVLSLIGIYA 183
ATP6 MTH00172
ATP synthase F0 subunit 6; Provisional
 1-176 1.06e-20

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 214447  Cd Length: 232  Bit Score: 85.09  E-value: 1.06e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911987   1 MTLSFFDQFMSPTLFGI--PLIALALFLPWILFPTPSSRWLNNRLLGLQSWSINRFTQQLLLPLNLGGHKWAVILTSLML 78
Cdd:MTH00172   1 MSSSYFDQFNIVWLIGLtnSSIMMILVIIVVLLLFKGIKLIPKRWQSIIEIIYNHFHGVVKDNLGNEGLKYFPFIISLFF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911987  79 FLITINMLGLLPYTYTPTTQLSLNLGLAVPLWLATVIIGLRNQPTAALGHLLPEGTPVPLIPILIIIETISLFIRPLALG 158
Cdd:MTH00172  81 FIVFLNLLGLFPYVFTPTTHIVVTLGLSFSIIIGVTLAGFWRFKWDFFSILMPSGAPLGLAPLLVLIETVSYISRAISLG 160

                        170
                 ....*....|....*...
gi 314911987 159 VRLTANLTAGHLLIQLIA 176
Cdd:MTH00172 161 VRLAANLSAGHLLFAILA 178
ATP-synt_A pfam00119
ATP synthase A chain;
65-179 2.70e-19

ATP synthase A chain;


Pssm-ID: 459679 [Multi-domain]  Cd Length: 216  Bit Score: 81.00  E-value: 2.70e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911987   65 GGHKWAVILTSLMLFLITINMLGLL---PYTYTPTTQLSLNLGLAVPLWLATVIIGLRNQPTAA-LGHLLPEGTPVPLIP 140
Cdd:pfam00119  53 KGRKFFPLLLTLFFFILVSNLLGLIpksPGGFTVTADINVTLALALIVFLLVHYYGIKKHGLGGyFKKLFVPPVPLPLVP 132

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 314911987  141 ILIIIETISLFIRPLALGVRLTANLTAGHLLIQLIATAA 179
Cdd:pfam00119 133 LLLPIEIISEFARPVSLSLRLFGNMLAGHLLLLLLAGLI 171
ATP6 MTH00175
ATP synthase F0 subunit 6; Provisional
 1-176 4.64e-17

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177228  Cd Length: 244  Bit Score: 75.81  E-value: 4.64e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911987   1 MTLSFFDQFMSPTLFGIPlialALFLPWILFPTPSSR---------WL---NNRLLGLQSWSINRFTQ---QLLLPLNLG 65
Cdd:MTH00175   1 MLAAYFDQFNIIRLITIQ----AFLGDWLVTFTNSSMmmvlaviifWLllkGDKLIPNRWQSIMELIYlniRSVVHDNLG 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911987  66 --GHKWAVILTSLMLFLITINMLGLLPYTYTPTTQLSLNLGLAVPLWLATVIIGLRNQPTAALGHLLPEGTPVPLIPILI 143
Cdd:MTH00175  77 ksGQKYFPFILSLFLFIAILNILGLFPYVFTPTAHIIITFGLSLSIIIAVTLLGFLTFKWNFLSILMPGGAPLVLAPFLV 156

                        170       180       190
                 ....*....|....*....|....*....|...
gi 314911987 144 IIETISLFIRPLALGVRLTANLTAGHLLIQLIA 176
Cdd:MTH00175 157 LIETLSYLIRAISLGVRLAANISAGHLLFAILS 189
AtpB COG0356
FoF1-type ATP synthase, membrane subunit a [Energy production and conversion]; FoF1-type ATP ...
 66-179 3.60e-14

FoF1-type ATP synthase, membrane subunit a [Energy production and conversion]; FoF1-type ATP synthase, membrane subunit a is part of the Pathway/BioSystem: FoF1-type ATP synthase


Pssm-ID: 440125 [Multi-domain]  Cd Length: 212  Bit Score: 67.41  E-value: 3.60e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911987  66 GHKWAVILTSLMLFLITINMLGLLPYTYTPTTQLSLNLGLAVPLWLATVIIGLRNQPTAA-LGHLLPEGTPVPLIPILII 144
Cdd:COG0356   54 GRKFAPLLLTLFLFILVSNLLGLIPGLFPPTADINVTLALALIVFVLVHYYGIKKKGLGGyLKHLFFPPFPWLAPLMLPI 133

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 314911987 145 iETISLFIRPLALGVRLTANLTAGHLLIQLIATAA 179
Cdd:COG0356  134 -EIISELARPLSLSLRLFGNMFAGHIILLLLAGLA 167
PRK05815 PRK05815
F0F1 ATP synthase subunit A; Validated
 66-179 2.55e-12

F0F1 ATP synthase subunit A; Validated


Pssm-ID: 235617  Cd Length: 227  Bit Score: 62.50  E-value: 2.55e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911987  66 GHKWAVILTSLMLFLITINMLGLLP-YTYTPTTQLSLNLGLAVPLWLATVIIGLRNQPTAA-LGHLLPEGTPVPLIPili 143
Cdd:PRK05815  69 GKKFAPLAFTLFLFILLMNLLGLIPyLLFPPTADINVTLALALIVFVLVIYYGIKKKGLGGyLKEFYLQPHPLLLPI--- 145

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 314911987 144 iiETISLFIRPLALGVRLTANLTAGHLLIQLIATAA 179
Cdd:PRK05815 146 --EIISEFSRPISLSLRLFGNMLAGELILALIALLG 179
ATP6 MTH00174
ATP synthase F0 subunit 6; Provisional
 63-179 6.25e-12

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 133799  Cd Length: 252  Bit Score: 61.88  E-value: 6.25e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911987  63 NLGGHKWAVILtSLMLFLITINMLGLLPYTYTPTTQLSLNLGLAVPLWLATVIIGLRNQPTAALGHLLPEGTPVPLIPIL 142
Cdd:MTH00174  85 NKGGNYLAFVL-SLFILILFGNGLGLFPYVFTPTVHMVITLGLSFAIIVGTTLAGLITFRFNFFSILMPQGAPLALAPLL 163

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 314911987 143 IIIETISLFIRPLALGVRLTANLTAGHLLIQLIATAA 179
Cdd:MTH00174 164 TIIETLSYISRAISLGVRLAANISSGHLLFSIIASFA 200
PRK13419 PRK13419
F0F1 ATP synthase subunit A; Provisional
 73-172 1.02e-10

F0F1 ATP synthase subunit A; Provisional


Pssm-ID: 237381  Cd Length: 342  Bit Score: 58.99  E-value: 1.02e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911987  73 LTSLMLFLITINMLGLLPYTYTPTTQLSLNLGLAVPLWLATVIIGLRNQPTAALGHLLPEGTPVPLIPILIIIETISLFI 152
Cdd:PRK13419 174 LLTVFFFILVCNLLGLVPYGATATGNINVTLTLAVFTFFITQYAAIKAHGIKGYLAHLTGGTHWSLWIIMIPIEFIGLFT 253

                         90       100
                 ....*....|....*....|
gi 314911987 153 RPLALGVRLTANLTAGHLLI 172
Cdd:PRK13419 254 KPFALTVRLFANMTAGHIVI 273
ATP6 MTH00087
ATP synthase F0 subunit 6; Provisional
 71-175 1.20e-08

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177152  Cd Length: 195  Bit Score: 52.29  E-value: 1.20e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911987  71 VILTSLMLFLITINMLGLLPYTYTPTTQLSLNLGLAVPLWLATVIIGLRNQptAALGHLLPEGTPV-PLIPILIIIETIS 149
Cdd:MTH00087  53 VISFFTFIVLLLFCFGGLFPYSFSPCGMVEFTFLYALVAWLSTFLSFLSKS--EKFSVYLSKGSDSfLKTFSMLFVEIVS 130

                         90       100
                 ....*....|....*....|....*.
gi 314911987 150 LFIRPLALGVRLTANLTAGHLLIQLI 175
Cdd:MTH00087 131 ELSRPLALTLRLTVNLMVGHLISSLL 156
PRK13417 PRK13417
F0F1 ATP synthase subunit A; Provisional
 94-172 1.18e-03

F0F1 ATP synthase subunit A; Provisional


Pssm-ID: 237380  Cd Length: 352  Bit Score: 38.33  E-value: 1.18e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314911987  94 TPTTQLSLNLGLAVPLWLATVIIGLRNQPTAALGHLLPEGTPVPLIPILIIIETI-SLFIRPLALGVRLTANLTAGHLLI 172
Cdd:PRK13417 217 TVTGDISVTMTLALLTMFLIYGAGFSYQGPKFIWHSVPNGVPLLLYPIMWPLEFIvSPMAKTFALTVRLLANMTAGHVII 296
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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