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Concise Results
Standard Results
Full Results
DNA polymerase II large subunit [Methanobacterium lacus]
Protein Classification
similar to DNA polymerase II large subunit ( domain architecture ID 11480105 )
protein similar to DNA polymerase II large subunit
List of domain hits
Name
Accession
Description
Interval
E-value
PRK04023
PRK04023 DNA polymerase II large subunit; Validated
1-1108
0e+00
DNA polymerase II large subunit; Validated
Pssm-ID: 235202 [Multi-domain]
Cd Length: 1121
Bit Score: 1814.89
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 1 MG YFE V LEKE TLK LYEIA KS ARSKG H D IEL E P EIPLAKD L AERVEGLVG P KGVA A RI K ELE TDI SREE V A FQ IA R EI V td 80
Cdd:PRK04023 6 ED YFE R LEKE LDE LYEIA EK ARSKG L D PSD E V EIPLAKD M AERVEGLVG I KGVA E RI R ELE KEM SREE A A LE IA K EI A -- 83
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 81 tdv EG RDDTLEVR E QKS DQA I RTALAILTEGVVAAPLEGIAK L KIK R N F D SGY YLA V Y F AGPIRSAGGTA A AL A VL I GDY 160
Cdd:PRK04023 84 --- EG KVGEFDSK E EAA DQA V RTALAILTEGVVAAPLEGIAK V KIK K N D D GTE YLA I Y Y AGPIRSAGGTA Q AL S VL V GDY 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 161 I R IS L E LD T YKP V D T EIERYVEE V ELY E s EVT N LQYSP KP EE V R KA V K NIPVE VT GEPT DKI EVS - HRDLERVETN N IRG 239
Cdd:PRK04023 161 V R RK L G LD R YKP T D D EIERYVEE I ELY K - EVT S LQYSP SD EE I R LI V R NIPVE ID GEPT EDE EVS g HRDLERVETN R IRG 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 240 G A LL AI AEG VIQ KAPK VM KY AK KLKIDGW D WL G E FSKAP - DPNADDSDAAP K VD DKY M RDII G GRPV MAY P QA KGGFRLR 318
Cdd:PRK04023 240 G M LL VL AEG IAL KAPK IL KY VD KLKIDGW E WL E E LISGK k EKEEEEEKKKI K PK DKY L RDII A GRPV FSH P SR KGGFRLR 319
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 319 YGRSRN A G L A AM G V HP S TM EIVE - F L AVGTQ M K I ERPGK GN CVVP C DSIEGP I V K LK D G S VV KVESEQQ AK K I KYQ VEEI 397
Cdd:PRK04023 320 YGRSRN T G F A TA G I HP A TM YLLD d F I AVGTQ L K V ERPGK AA CVVP V DSIEGP T V R LK N G D VV RIDDVEE AK E I RDD VEEI 399
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 398 VF LG DM L VPF G E FL R NNH IM LP AGW C S EWW V Q TIQKSESYQ E SDL D I kslet E KIDAKT A FE ISE K Y D VPLHP D YTY CY H 477
Cdd:PRK04023 400 LD LG EI L INY G D FL E NNH PL LP SSY C E EWW I Q ELEAAGAEY E PEF D L ----- E NPSQEE A LK ISE E Y G VPLHP K YTY LW H 474
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 478 D VTTQDINE L I qfinrelktsddpdl K A VSERIYD E g S G G L K L PI S PE - KRILE V LG I PH EIDGDELI I sr E D AY V LL NT 556
Cdd:PRK04023 475 D ISKEELEA L R --------------- N A LAGGGIL E - E G V L V L DL S EG v KRILE K LG V PH RVRDGKIV I -- E E AY P LL YS 536
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 557 L NRPVET E ------- GSN T LEAVN SIAPVQ I MA KAPT YL GAR V GRPEK S KERKMKP AP H A LFPIG TN GG NR R N I ID AAK - 628
Cdd:PRK04023 537 L GLDELE E lkkkldd GSN V LEAVN ELSGFE I RP KAPT RI GAR M GRPEK A KERKMKP PV H V LFPIG NA GG ST R D I NK AAK y 616
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 629 KGTI N V D I A R C KC TE CG VGSMQAL CP V CG AR T ----------------------- EPT SSG K KR I N L AN L LKK A Y EN V G V 685
Cdd:PRK04023 617 KGTI E V E I G R R KC PS CG KETFYRR CP F CG TH T epvyrcprcgieveedecekcgr EPT PYS K RK I D L KE L YDR A L EN L G E 696
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 686 RK - I DE I KGV V G MI S E DK F PEPLEKGILRAK N DV FT FKD A T I R H D S T N LPLTHF I P S EIGV TPQ KL L ELGYT N DI H G DKI 764
Cdd:PRK04023 697 RK n F DE V KGV K G LT S K DK I PEPLEKGILRAK H DV YV FKD G T V R Y D M T D LPLTHF R P R EIGV SVE KL R ELGYT H DI Y G NPL 776
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 765 E DP DQIVE I K I QDV VV S ENCGD YL I RV SH F V DDLLE QL YGLE R FYNV QT REDL V G Q LV V GLAPHTSAGV L GRI V GFTKA A 844
Cdd:PRK04023 777 E SE DQIVE L K V QDV II S RDAAE YL L RV AK F I DDLLE KY YGLE P FYNV EK REDL I G H LV I GLAPHTSAGV V GRI I GFTKA N 856
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 845 CC YAHPYFH S AKRRNCD S DED SI MLLLD A LLNFS KV YLP ST RGG K MDAPLVL SS RIDP E E I DDE S HN I D AMPYI PLE L YE 924
Cdd:PRK04023 857 VG YAHPYFH A AKRRNCD G DED CV MLLLD G LLNFS RS YLP DK RGG Q MDAPLVL TT RIDP K E V DDE A HN M D VVWRY PLE F YE 936
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 925 K TL DFEK P SD V L D LV D N V KR RLGT ED QY Q G LIYS H T TS S I HS GPKV CL YKTL PT M K EK VDG Q IK LA ER IRAVD QKG V V E G 1004
Cdd:PRK04023 937 A TL EGAD P KE V E D IM D T V ED RLGT PE QY E G FMFT H D TS D I AA GPKV SA YKTL GS M E EK MEA Q LE LA RK IRAVD ERD V A E R 1016
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 1005 V LT SHFLPD MA GN S RAFSRQ KV RCTKCG R KYRR I PLSG N C S - CG S NLIL SIS KGSV V KYLE I SK N L SQR Y PIDE Y LV QR I 1083
Cdd:PRK04023 1017 V IS SHFLPD LI GN L RAFSRQ EF RCTKCG A KYRR P PLSG K C P k CG G NLIL TVH KGSV E KYLE V SK K L AEE Y GVSD Y TK QR L 1096
1130 1140
....*....|....*....|....*
gi 325331683 1084 EL I E TS I N SLFE S DKSKQS S L DV F L 1108
Cdd:PRK04023 1097 EL L E RG I K SLFE N DKSKQS G L SD F F 1121
Name
Accession
Description
Interval
E-value
PRK04023
PRK04023 DNA polymerase II large subunit; Validated
1-1108
0e+00
DNA polymerase II large subunit; Validated
Pssm-ID: 235202 [Multi-domain]
Cd Length: 1121
Bit Score: 1814.89
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 1 MG YFE V LEKE TLK LYEIA KS ARSKG H D IEL E P EIPLAKD L AERVEGLVG P KGVA A RI K ELE TDI SREE V A FQ IA R EI V td 80
Cdd:PRK04023 6 ED YFE R LEKE LDE LYEIA EK ARSKG L D PSD E V EIPLAKD M AERVEGLVG I KGVA E RI R ELE KEM SREE A A LE IA K EI A -- 83
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 81 tdv EG RDDTLEVR E QKS DQA I RTALAILTEGVVAAPLEGIAK L KIK R N F D SGY YLA V Y F AGPIRSAGGTA A AL A VL I GDY 160
Cdd:PRK04023 84 --- EG KVGEFDSK E EAA DQA V RTALAILTEGVVAAPLEGIAK V KIK K N D D GTE YLA I Y Y AGPIRSAGGTA Q AL S VL V GDY 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 161 I R IS L E LD T YKP V D T EIERYVEE V ELY E s EVT N LQYSP KP EE V R KA V K NIPVE VT GEPT DKI EVS - HRDLERVETN N IRG 239
Cdd:PRK04023 161 V R RK L G LD R YKP T D D EIERYVEE I ELY K - EVT S LQYSP SD EE I R LI V R NIPVE ID GEPT EDE EVS g HRDLERVETN R IRG 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 240 G A LL AI AEG VIQ KAPK VM KY AK KLKIDGW D WL G E FSKAP - DPNADDSDAAP K VD DKY M RDII G GRPV MAY P QA KGGFRLR 318
Cdd:PRK04023 240 G M LL VL AEG IAL KAPK IL KY VD KLKIDGW E WL E E LISGK k EKEEEEEKKKI K PK DKY L RDII A GRPV FSH P SR KGGFRLR 319
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 319 YGRSRN A G L A AM G V HP S TM EIVE - F L AVGTQ M K I ERPGK GN CVVP C DSIEGP I V K LK D G S VV KVESEQQ AK K I KYQ VEEI 397
Cdd:PRK04023 320 YGRSRN T G F A TA G I HP A TM YLLD d F I AVGTQ L K V ERPGK AA CVVP V DSIEGP T V R LK N G D VV RIDDVEE AK E I RDD VEEI 399
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 398 VF LG DM L VPF G E FL R NNH IM LP AGW C S EWW V Q TIQKSESYQ E SDL D I kslet E KIDAKT A FE ISE K Y D VPLHP D YTY CY H 477
Cdd:PRK04023 400 LD LG EI L INY G D FL E NNH PL LP SSY C E EWW I Q ELEAAGAEY E PEF D L ----- E NPSQEE A LK ISE E Y G VPLHP K YTY LW H 474
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 478 D VTTQDINE L I qfinrelktsddpdl K A VSERIYD E g S G G L K L PI S PE - KRILE V LG I PH EIDGDELI I sr E D AY V LL NT 556
Cdd:PRK04023 475 D ISKEELEA L R --------------- N A LAGGGIL E - E G V L V L DL S EG v KRILE K LG V PH RVRDGKIV I -- E E AY P LL YS 536
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 557 L NRPVET E ------- GSN T LEAVN SIAPVQ I MA KAPT YL GAR V GRPEK S KERKMKP AP H A LFPIG TN GG NR R N I ID AAK - 628
Cdd:PRK04023 537 L GLDELE E lkkkldd GSN V LEAVN ELSGFE I RP KAPT RI GAR M GRPEK A KERKMKP PV H V LFPIG NA GG ST R D I NK AAK y 616
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 629 KGTI N V D I A R C KC TE CG VGSMQAL CP V CG AR T ----------------------- EPT SSG K KR I N L AN L LKK A Y EN V G V 685
Cdd:PRK04023 617 KGTI E V E I G R R KC PS CG KETFYRR CP F CG TH T epvyrcprcgieveedecekcgr EPT PYS K RK I D L KE L YDR A L EN L G E 696
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 686 RK - I DE I KGV V G MI S E DK F PEPLEKGILRAK N DV FT FKD A T I R H D S T N LPLTHF I P S EIGV TPQ KL L ELGYT N DI H G DKI 764
Cdd:PRK04023 697 RK n F DE V KGV K G LT S K DK I PEPLEKGILRAK H DV YV FKD G T V R Y D M T D LPLTHF R P R EIGV SVE KL R ELGYT H DI Y G NPL 776
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 765 E DP DQIVE I K I QDV VV S ENCGD YL I RV SH F V DDLLE QL YGLE R FYNV QT REDL V G Q LV V GLAPHTSAGV L GRI V GFTKA A 844
Cdd:PRK04023 777 E SE DQIVE L K V QDV II S RDAAE YL L RV AK F I DDLLE KY YGLE P FYNV EK REDL I G H LV I GLAPHTSAGV V GRI I GFTKA N 856
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 845 CC YAHPYFH S AKRRNCD S DED SI MLLLD A LLNFS KV YLP ST RGG K MDAPLVL SS RIDP E E I DDE S HN I D AMPYI PLE L YE 924
Cdd:PRK04023 857 VG YAHPYFH A AKRRNCD G DED CV MLLLD G LLNFS RS YLP DK RGG Q MDAPLVL TT RIDP K E V DDE A HN M D VVWRY PLE F YE 936
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 925 K TL DFEK P SD V L D LV D N V KR RLGT ED QY Q G LIYS H T TS S I HS GPKV CL YKTL PT M K EK VDG Q IK LA ER IRAVD QKG V V E G 1004
Cdd:PRK04023 937 A TL EGAD P KE V E D IM D T V ED RLGT PE QY E G FMFT H D TS D I AA GPKV SA YKTL GS M E EK MEA Q LE LA RK IRAVD ERD V A E R 1016
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 1005 V LT SHFLPD MA GN S RAFSRQ KV RCTKCG R KYRR I PLSG N C S - CG S NLIL SIS KGSV V KYLE I SK N L SQR Y PIDE Y LV QR I 1083
Cdd:PRK04023 1017 V IS SHFLPD LI GN L RAFSRQ EF RCTKCG A KYRR P PLSG K C P k CG G NLIL TVH KGSV E KYLE V SK K L AEE Y GVSD Y TK QR L 1096
1130 1140
....*....|....*....|....*
gi 325331683 1084 EL I E TS I N SLFE S DKSKQS S L DV F L 1108
Cdd:PRK04023 1097 EL L E RG I K SLFE N DKSKQS G L SD F F 1121
polC
TIGR00354 DNA polymerase, archaeal type II, large subunit; This model represents the large subunit, DP2, ...
1-1107
0e+00
DNA polymerase, archaeal type II, large subunit; This model represents the large subunit, DP2, of a two subunit novel Archaeal replicative DNA polymerase first characterized for Pyrococcus furiosus. Structure of DP2 appears to be organized as a ~950 residue component separated from a ~300 residue component by a ~150 residue intein. The other subunit, DP1, has sequence similarity to the eukaryotic DNA polymerase delta small subunit. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273031 [Multi-domain]
Cd Length: 1095
Bit Score: 1566.80
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 1 MG YFE V L EK E TLKL Y E IA KS AR S KG H D I EL EP EIPLAKD L AERVEGLVGP K G V A A RI K ELE TDIS RE EV AF Q IA R EIV TD 80
Cdd:TIGR00354 4 RR YFE S L MV E LDRI Y R IA EA AR K KG L D P EL SV EIPLAKD M AERVEGLVGP Q G L A K RI M ELE GGLG RE LI AF K IA D EIV EG 83
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 81 T dv E G RD D tlev R E QKS DQA I RTALAILTEGVVAAPLEGIA KLK IKRNFD SGY YLAVY F AGPIRSAGGTA A AL A VL IG DY 160
Cdd:TIGR00354 84 K -- F G EM D ---- K E KAA DQA V RTALAILTEGVVAAPLEGIA RVR IKRNFD KSN YLAVY Y AGPIRSAGGTA Q AL S VL VA DY 157
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 161 I R ISLE LD T YKP VDT EIERYVEEVELY E SEV T NLQY S P KPE E V R K AV K NIP V E V TGEPTD KI EVS - HRDL E RVETN NI RG 239
Cdd:TIGR00354 158 V R RAAG LD R YKP TEE EIERYVEEVELY K SEV A NLQY L P SDD E I R L AV S NIP I E I TGEPTD SV EVS g HRDL P RVETN RV RG 237
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 240 GALL A I A EGV IQ KAPK VM K YAKK L K I D GWDWL GEFS -- K APDPNADDSDAAP K VD DKY MR DII G GRPV M A Y P QA KGGFRL 317
Cdd:TIGR00354 238 GALL V I V EGV AL KAPK LL K MVDE L G I E GWDWL DALI kg K GDKGSEGEEKVVI K AK DKY LS DII A GRPV L A H P SR KGGFRL 317
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 318 RYGR S RN A G L A AM GVHP S TM EIV EF L AVGTQ M K I ERPGK GN CVVP C D S IEGP I VKLK D G S V VKVESEQQ AK KIKYQ VEEI 397
Cdd:TIGR00354 318 RYGR A RN T G F A TV GVHP A TM YLL EF V AVGTQ L K V ERPGK AG CVVP V D T IEGP T VKLK N G D V IRINTLEE AK AVRGE VEEI 397
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 398 V FLGD M LV PF G E FL R NNH IML PA G WC S EWW V Q TIQ K SESYQESD l D IKSLET E K idakt A FEISEKYD VPLHP D YTY CY H 477
Cdd:TIGR00354 398 L FLGD I LV NY G D FL E NNH PLI PA S WC E EWW I Q EAE K ANLSYLRG - D YRKISE E E ----- A LKLCDEFH VPLHP R YTY LW H 471
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 478 DV TTQ D INE L IQFINREL K T s DDPDL K AVSERIY D egsgglklpi S PE KRILE V LG IP H EIDGDELI I SRE ---- DAYV L 553
Cdd:TIGR00354 472 DV SVE D YRY L RNWLSDNG K L - EGKHG K SDLLLPE D ---------- S RV KRILE A LG LE H KVRESFVV I ETW rafi RCLG L 540
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 554 LNT L NRPV E T e GSNT LE A VN S I A P VQIMA KA PT Y L GAR V GRPEK S KERKM K P A PH A LFPIG TN GGN R R N I ID A AKKG - T I 632
Cdd:TIGR00354 541 DEK L SKVL E V - SKDV LE I VN G I S P IKVRP KA LS Y I GAR M GRPEK A KERKM S P P PH I LFPIG MA GGN T R D I KN A INYT k E I 619
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 633 N V D IA RC KC TE CG VG S MQAL CPVCG AR TE PTSS GK KRIN L AN L LKK A YE N V G VR K I D E IKGV V GM I S ED K F PEPLEKGIL 712
Cdd:TIGR00354 620 E V E IA IR KC PQ CG KE S FWLK CPVCG EL TE QLYY GK RKVD L RE L YEE A IA N L G EY K F D T IKGV K GM T S KT K I PEPLEKGIL 699
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 713 RAKN D V FT FKD A T I R H D S T N LP L THF I P S EIGV TPQ KL L ELGY TN D IH G DKIE D PD QIVE I K I QDV VVS E N C GD YL I RV S 792
Cdd:TIGR00354 700 RAKN G V YV FKD G T A R F D A T D LP I THF K P A EIGV SVE KL R ELGY ER D YY G AELK D EN QIVE L K P QDV IIP E S C AE YL V RV A 779
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 793 H F V DDLLE QL Y GL ERFYNV QTR EDL V G Q LV V GLAPHTSAGVLGRI V GFT K A ACC YAHPYFH S AKRRNCD S DEDS I MLLLD 872
Cdd:TIGR00354 780 N F I DDLLE KF Y KM ERFYNV KSV EDL I G H LV I GLAPHTSAGVLGRI I GFT D A LAG YAHPYFH A AKRRNCD G DEDS F MLLLD 859
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 873 ALLNFSK VY LP ST RGG K MDAPLVL SSRI DP E E I D D E S HN I D A M PYI PLE L YE K T LD F EK P SD V L D L V DN V KR RLG TED QY 952
Cdd:TIGR00354 860 ALLNFSK KF LP DK RGG Q MDAPLVL TTIV DP R E V D K E V HN M D T M ERY PLE F YE A T MR F PS P KE V E D Y V EK V ED RLG KPE QY 939
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 953 Q GL IYS H T TS S I HS GPKVC L YK T L P TM K EKV DG Q IK LA ER IRAVD QKG V V E G V LT SHFLPD MA GN S RAFSRQ K VRCTKC G 1032
Cdd:TIGR00354 940 C GL FFT H D TS R I DA GPKVC A YK S L K TM Q EKV YS Q ME LA RK IRAVD ERD V A E R V IN SHFLPD II GN L RAFSRQ E VRCTKC N 1019
1050 1060 1070 1080 1090 1100 1110
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 325331683 1033 R KYRRIPL S G N C - S CG S NL I L SI SKGSV V KYLE I SK N L SQR Y PIDE Y LV QR IELI E TS INS L FE SDK SKQ S SL DV F 1107
Cdd:TIGR00354 1020 T KYRRIPL V G K C l K CG N NL T L TV SKGSV M KYLE L SK F L AEN Y NVSS Y TK QR LMIL E QG INS M FE NGT SKQ V SL SD F 1095
PolC_DP2
pfam03833 DNA polymerase II large subunit DP2;
3-859
0e+00
DNA polymerase II large subunit DP2;
Pssm-ID: 427537
Cd Length: 866
Bit Score: 1364.91
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 3 YFE V LEKE TLKL YEIA KS ARS K G H D IEL E P EIPLAKDLA E RVE G L V G P KGVA A RI K ELE TDI SREE V A FQ IA R EI V tdtd 82
Cdd:pfam03833 2 YFE R LEKE LDEA YEIA EK ARS R G L D PSP E V EIPLAKDLA D RVE K L L G I KGVA E RI R ELE KTM SREE A A LE IA K EI A ---- 77
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 83 v EG RDDTLEVR E QKS DQA I RTALAILTEGVVAAPLEGIA KL KIK R N F D SGY YL A VY F AGPIRSAGGTA A AL A VL IG DY I R 162
Cdd:pfam03833 78 - EG KVGDFDSK E EAL DQA V RTALAILTEGVVAAPLEGIA RV KIK K N D D GTE YL S VY Y AGPIRSAGGTA Q AL S VL VA DY V R 156
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 163 IS L EL D T YKP V D T EIERYVEE V ELY ES e VT N LQYSP KP EE V R KA V K N I PV EVT GEPT DKI EVS - HRDLERVETN NI RGG A 241
Cdd:pfam03833 157 RL L GI D R YKP R D E EIERYVEE I ELY KR - VT H LQYSP SD EE I R LI V R N C PV CID GEPT EDE EVS g HRDLERVETN RV RGG M 235
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 242 L L AI AEG VIQ KAPK VM K YA KKL K IDGW D WL G E F --- S KA PDPNADDSDAAP K VD DKY M RD I I G GRPV MAY P QAK GGFRLR 318
Cdd:pfam03833 236 C L VL AEG IAL KAPK IL K HV KKL G IDGW E WL D E L ikg D KA EKTGEEEEKPRV K PK DKY L RD L I A GRPV FSH P SRP GGFRLR 315
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 319 YGRSRN A G L A AM G V HP S TM E I V - E F L AVGTQ M K I ERPGK GNC VVP C DSIEGP I V K LK D G S VV KVESEQQ A KK I KYQ VEEI 397
Cdd:pfam03833 316 YGRSRN T G F A TA G I HP A TM H I L d D F I AVGTQ L K V ERPGK AAG VVP V DSIEGP T V R LK N G D VV RIDDVEE A LE I RND VEEI 395
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 398 VF LG DM L VPF G E FL R NNH IML P AGW C S EWW V Q TIQKSESYQESD ldikslet E KID A KT A F EIS EK Y D VPLHPDYTY CY H 477
Cdd:pfam03833 396 LD LG EI L INY G D FL E NNH PLV P SSY C E EWW I Q ELEAAGADVQAL -------- E DPT A EE A L EIS KE Y G VPLHPDYTY LW H 467
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 478 D VTTQDI N E L IQFINREL K TS ddpdlkavseriydegs G G L K LP IS PE - KRILE V L GI PH EIDGDEL II sr E D A Y V LL NT 556
Cdd:pfam03833 468 D ISVEEL N A L ADAVAKGG K IG ----------------- G V L V LP LD PE i KRILE K L LV PH KVRDGKI II -- D D W Y P LL RC 528
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 557 L NRPVET ------ E GSNT LEAVN SIAPVQIM A K APT YL GAR V GRPEKSKERKMKP AP H A LFPIG TN GG N RR N I ID AAK -- 628
Cdd:pfam03833 529 L GLDEDL gklske E RKDA LEAVN ELSGFKVR A R APT RI GAR M GRPEKSKERKMKP PV H V LFPIG EA GG S RR D I AE AAK ya 608
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 629 -- KG T I N V D I A R CK C TE CG VGSMQAL CP V CGA R TEP ----------------------- T SSG K KR I N L ANLLKK A Y EN V 683
Cdd:pfam03833 609 en KG E I E V E I G R RR C PN CG KETFENR CP D CGA H TEP vyvcpkcgievedekcpkcgrea T CVS K IK I D L KKEYRR A L EN L 688
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 684 G V R -- KI DE I KGV V G MI S E DK F PEPLEKGILRAK ND V FT FKD A T I R H D S T N LPLTHF I P S EIGV TPQ KL L ELGYT N DI H G 761
Cdd:pfam03833 689 G E R en AL DE L KGV K G LT S K DK T PEPLEKGILRAK HG V SV FKD G T V R Y D M T D LPLTHF R P R EIGV SVE KL R ELGYT H DI Y G 768
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 762 DKI E DP DQIVE I K I QD VVV SE NCGD YL IR V SH F V DDLLE QL YGLE R FYNV QT REDL V G Q LV V GLAPHTSAGVLGRI V GFT 841
Cdd:pfam03833 769 KPL E SE DQIVE L K V QD IIL SE DAAE YL LK V AK F I DDLLE KY YGLE P FYNV ED REDL I G H LV I GLAPHTSAGVLGRI I GFT 848
890
....*....|....*...
gi 325331683 842 KA ACC YAHPYFH S AKRRN 859
Cdd:pfam03833 849 KA SVG YAHPYFH A AKRRN 866
PolC
COG1933 Archaeal DNA polymerase II, large subunit [Replication, recombination and repair];
40-1107
0e+00
Archaeal DNA polymerase II, large subunit [Replication, recombination and repair];
Pssm-ID: 441536 [Multi-domain]
Cd Length: 1075
Bit Score: 940.46
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 40 LA E RVEGLV G PKGV AA RIKELETDIS R EEV A FQIAREIVTDTDVEGRDDT LE VRE qks D QAIRTALAI LTEGVVAA PLE G 119
Cdd:COG1933 7 EL E EELAEE G EEEI AA ELGAERAGEA R AGL A AELEAKVRAVLKLLEAAAA LE AGI --- D AEAGAGALA LTEGVVAA AGQ G 83
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 120 IAKLK IK RNFDSGYYLAVYFA G PIRSAG G TA A ALAV L I G DYI R IS LE LDT Y -- KPVDT E IE R YV E EVELY E SEVTNLQ - Y 196
Cdd:COG1933 84 AEAAA IK AAGGGAVEGSIVRR G GGGRVR G GE A EEEA L A G EVR R KV LE IED Y dr LSEVD E EV R EE E LLLAE E EDEEEEE e E 163
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 197 SPKP EE VRKAVKNIPV E VTGEPTDKIE V SHRDLERVETNNIR G GA LL AIAE G VIQKAPKVMKYAK K LKIDGWDW L GEFSK 276
Cdd:COG1933 164 EVED EE ADEVEEDDEE E GGLGLELRAL V LVVGRDLKADKAEG G NV LL TDLD G EGEEGEDDEGDEG K DEDGEEAV L RDEGG 243
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 277 A P DPNADDSDAAPKVDD K YMRDIIGGRPVMAYPQAKGGFRLRYGRSRNA G L A AM G VH PS TMEI V EFLA V GTQMKIERPGK 356
Cdd:COG1933 244 G P LEPLVGGRVGDLARE K GGTLAALVAGGGRILAGLLLGDGAVTLGEAL G V A VV G GA PS EGGG V GLEG V VVVLRGGSLVV 323
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 357 GNC V VPCDSIEGPIVKLKDGSVVKVESEQQAKKIKYQVEEIVFLGDMLVPFG E FLRNNHIMLPAGWCS E WWVQTIQKS ES 436
Cdd:COG1933 324 LGV V AAVKITGRVEEEIVVKEEDDLDEREIDLDDELLGPGEPEELLVAELLE E PDGEELSGEVEEEEE E LDELEEEAE ES 403
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 437 YQ E S D L D IKS L ETEKI DA KTAFEIS E KYDVP L HPDYTYCYHDVTTQDIN EL IQFINRELKTSDDPD L KAVS E RIYDEGSG 516
Cdd:COG1933 404 RE E G D E D EEE L TEREE DA LSLKLEL E RELEG L LTEEEEELLELLEELLL EL LDEELEDELILELLI L LEEE E EEELILDL 483
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 517 G L K L PI S PE K RI L EV L GIPHEIDG D ELIISREDAYVLLNTLN R PVETEG S NTLEAVNSIAP V QIMAKAPTY LG ARVGRPE 596
Cdd:COG1933 484 L L E L DL S EL K KG L KL L SDREVAPF D LESGGLVALKSRMVRPR R RERRDL S DRRRTLEPAGE V GPPIGDVGL LG RGLRGAA 563
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 597 KSKERKMKPAPHALF PI GTNGGNRRNIIDAAKKGTINVDIAR C KCTE C GVG S MQAL CP V CG ART EP TS S GK K RIN L ANL L 676
Cdd:COG1933 564 DTDLKEAAGVGLFKE PI LRLECCECGEPSCEICIECGLEKPY C LICC C PDE S GRDE CP C CG CGR EP ST S SR K DFP L KKR L 643
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 677 KK A Y EN VGV R KI D EI KGV V G MI S E DK F PEPLEKGILRAK N DV FT FKD A T I R H D S T N LPLTHF I PSEIGVT PQ KL L ELGYT 756
Cdd:COG1933 644 AA A E EN GRE R AL D PL KGV K G LT S R DK T PEPLEKGILRAK H DV SV FKD G T V R Y D M T D LPLTHF R PSEIGVT VE KL R ELGYT 723
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 757 N DI H G DKI E DP DQ I VE I K I QD VVV SE NCGD YL I RV SH F V DDLLE QL YGLE R FYN VQT REDL V G Q LV V GLAPHTSAGV L GR 836
Cdd:COG1933 724 E DI L G KPL E SE DQ L VE L K V QD III SE DAAE YL L RV AK F I DDLLE KY YGLE P FYN AED REDL I G H LV I GLAPHTSAGV V GR 803
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 837 I V GFT K A ACC YAHPYFH S AKRRNCD S DED SI MLLLD A LLNFS KVY LP ST RGG K MDAPLVL S SRIDP E EIDDE S HN I D AMP 916
Cdd:COG1933 804 I I GFT L A VVG YAHPYFH A AKRRNCD G DED CV MLLLD G LLNFS RSF LP DK RGG L MDAPLVL T SRIDP S EIDDE A HN M D VVS 883
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 917 YI PLE L YE K TL DFEK P SD V L DL V D N V KR RLGT ED QY Q G LIYS H T TS S I HS GP KVCL YKTL PT M KE K V D G Q IK LA ER IRAV 996
Cdd:COG1933 884 RY PLE F YE A TL EMAD P KE V E DL I D I V ED RLGT DG QY E G FGFT H D TS D I AA GP DLSA YKTL GS M MD K M D A Q LE LA RK IRAV 963
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 997 D QKG V V E G V LT SHFLPD MA GN S RAFSRQ KV RC T KCG R KYRR I PL S G N C - S CG S N L IL SISK GSV V KYLE IS K NLSQR Y PI 1075
Cdd:COG1933 964 D ETD V A E R V IE SHFLPD LI GN L RAFSRQ EF RC L KCG A KYRR M PL T G K C r K CG G N V IL TVHE GSV N KYLE TA K KVAEE Y DV 1043
1050 1060 1070
....*....|....*....|....*....|..
gi 325331683 1076 DE Y LV QR I E LI E T SI N SLFE S DK S KQS S L DV F 1107
Cdd:COG1933 1044 RD Y TK QR L E IL E R SI E SLFE N DK N KQS G L AD F 1075
Name
Accession
Description
Interval
E-value
PRK04023
PRK04023 DNA polymerase II large subunit; Validated
1-1108
0e+00
DNA polymerase II large subunit; Validated
Pssm-ID: 235202 [Multi-domain]
Cd Length: 1121
Bit Score: 1814.89
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 1 MG YFE V LEKE TLK LYEIA KS ARSKG H D IEL E P EIPLAKD L AERVEGLVG P KGVA A RI K ELE TDI SREE V A FQ IA R EI V td 80
Cdd:PRK04023 6 ED YFE R LEKE LDE LYEIA EK ARSKG L D PSD E V EIPLAKD M AERVEGLVG I KGVA E RI R ELE KEM SREE A A LE IA K EI A -- 83
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 81 tdv EG RDDTLEVR E QKS DQA I RTALAILTEGVVAAPLEGIAK L KIK R N F D SGY YLA V Y F AGPIRSAGGTA A AL A VL I GDY 160
Cdd:PRK04023 84 --- EG KVGEFDSK E EAA DQA V RTALAILTEGVVAAPLEGIAK V KIK K N D D GTE YLA I Y Y AGPIRSAGGTA Q AL S VL V GDY 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 161 I R IS L E LD T YKP V D T EIERYVEE V ELY E s EVT N LQYSP KP EE V R KA V K NIPVE VT GEPT DKI EVS - HRDLERVETN N IRG 239
Cdd:PRK04023 161 V R RK L G LD R YKP T D D EIERYVEE I ELY K - EVT S LQYSP SD EE I R LI V R NIPVE ID GEPT EDE EVS g HRDLERVETN R IRG 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 240 G A LL AI AEG VIQ KAPK VM KY AK KLKIDGW D WL G E FSKAP - DPNADDSDAAP K VD DKY M RDII G GRPV MAY P QA KGGFRLR 318
Cdd:PRK04023 240 G M LL VL AEG IAL KAPK IL KY VD KLKIDGW E WL E E LISGK k EKEEEEEKKKI K PK DKY L RDII A GRPV FSH P SR KGGFRLR 319
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 319 YGRSRN A G L A AM G V HP S TM EIVE - F L AVGTQ M K I ERPGK GN CVVP C DSIEGP I V K LK D G S VV KVESEQQ AK K I KYQ VEEI 397
Cdd:PRK04023 320 YGRSRN T G F A TA G I HP A TM YLLD d F I AVGTQ L K V ERPGK AA CVVP V DSIEGP T V R LK N G D VV RIDDVEE AK E I RDD VEEI 399
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 398 VF LG DM L VPF G E FL R NNH IM LP AGW C S EWW V Q TIQKSESYQ E SDL D I kslet E KIDAKT A FE ISE K Y D VPLHP D YTY CY H 477
Cdd:PRK04023 400 LD LG EI L INY G D FL E NNH PL LP SSY C E EWW I Q ELEAAGAEY E PEF D L ----- E NPSQEE A LK ISE E Y G VPLHP K YTY LW H 474
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 478 D VTTQDINE L I qfinrelktsddpdl K A VSERIYD E g S G G L K L PI S PE - KRILE V LG I PH EIDGDELI I sr E D AY V LL NT 556
Cdd:PRK04023 475 D ISKEELEA L R --------------- N A LAGGGIL E - E G V L V L DL S EG v KRILE K LG V PH RVRDGKIV I -- E E AY P LL YS 536
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 557 L NRPVET E ------- GSN T LEAVN SIAPVQ I MA KAPT YL GAR V GRPEK S KERKMKP AP H A LFPIG TN GG NR R N I ID AAK - 628
Cdd:PRK04023 537 L GLDELE E lkkkldd GSN V LEAVN ELSGFE I RP KAPT RI GAR M GRPEK A KERKMKP PV H V LFPIG NA GG ST R D I NK AAK y 616
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 629 KGTI N V D I A R C KC TE CG VGSMQAL CP V CG AR T ----------------------- EPT SSG K KR I N L AN L LKK A Y EN V G V 685
Cdd:PRK04023 617 KGTI E V E I G R R KC PS CG KETFYRR CP F CG TH T epvyrcprcgieveedecekcgr EPT PYS K RK I D L KE L YDR A L EN L G E 696
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 686 RK - I DE I KGV V G MI S E DK F PEPLEKGILRAK N DV FT FKD A T I R H D S T N LPLTHF I P S EIGV TPQ KL L ELGYT N DI H G DKI 764
Cdd:PRK04023 697 RK n F DE V KGV K G LT S K DK I PEPLEKGILRAK H DV YV FKD G T V R Y D M T D LPLTHF R P R EIGV SVE KL R ELGYT H DI Y G NPL 776
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 765 E DP DQIVE I K I QDV VV S ENCGD YL I RV SH F V DDLLE QL YGLE R FYNV QT REDL V G Q LV V GLAPHTSAGV L GRI V GFTKA A 844
Cdd:PRK04023 777 E SE DQIVE L K V QDV II S RDAAE YL L RV AK F I DDLLE KY YGLE P FYNV EK REDL I G H LV I GLAPHTSAGV V GRI I GFTKA N 856
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 845 CC YAHPYFH S AKRRNCD S DED SI MLLLD A LLNFS KV YLP ST RGG K MDAPLVL SS RIDP E E I DDE S HN I D AMPYI PLE L YE 924
Cdd:PRK04023 857 VG YAHPYFH A AKRRNCD G DED CV MLLLD G LLNFS RS YLP DK RGG Q MDAPLVL TT RIDP K E V DDE A HN M D VVWRY PLE F YE 936
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 925 K TL DFEK P SD V L D LV D N V KR RLGT ED QY Q G LIYS H T TS S I HS GPKV CL YKTL PT M K EK VDG Q IK LA ER IRAVD QKG V V E G 1004
Cdd:PRK04023 937 A TL EGAD P KE V E D IM D T V ED RLGT PE QY E G FMFT H D TS D I AA GPKV SA YKTL GS M E EK MEA Q LE LA RK IRAVD ERD V A E R 1016
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 1005 V LT SHFLPD MA GN S RAFSRQ KV RCTKCG R KYRR I PLSG N C S - CG S NLIL SIS KGSV V KYLE I SK N L SQR Y PIDE Y LV QR I 1083
Cdd:PRK04023 1017 V IS SHFLPD LI GN L RAFSRQ EF RCTKCG A KYRR P PLSG K C P k CG G NLIL TVH KGSV E KYLE V SK K L AEE Y GVSD Y TK QR L 1096
1130 1140
....*....|....*....|....*
gi 325331683 1084 EL I E TS I N SLFE S DKSKQS S L DV F L 1108
Cdd:PRK04023 1097 EL L E RG I K SLFE N DKSKQS G L SD F F 1121
polC
TIGR00354 DNA polymerase, archaeal type II, large subunit; This model represents the large subunit, DP2, ...
1-1107
0e+00
DNA polymerase, archaeal type II, large subunit; This model represents the large subunit, DP2, of a two subunit novel Archaeal replicative DNA polymerase first characterized for Pyrococcus furiosus. Structure of DP2 appears to be organized as a ~950 residue component separated from a ~300 residue component by a ~150 residue intein. The other subunit, DP1, has sequence similarity to the eukaryotic DNA polymerase delta small subunit. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273031 [Multi-domain]
Cd Length: 1095
Bit Score: 1566.80
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 1 MG YFE V L EK E TLKL Y E IA KS AR S KG H D I EL EP EIPLAKD L AERVEGLVGP K G V A A RI K ELE TDIS RE EV AF Q IA R EIV TD 80
Cdd:TIGR00354 4 RR YFE S L MV E LDRI Y R IA EA AR K KG L D P EL SV EIPLAKD M AERVEGLVGP Q G L A K RI M ELE GGLG RE LI AF K IA D EIV EG 83
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 81 T dv E G RD D tlev R E QKS DQA I RTALAILTEGVVAAPLEGIA KLK IKRNFD SGY YLAVY F AGPIRSAGGTA A AL A VL IG DY 160
Cdd:TIGR00354 84 K -- F G EM D ---- K E KAA DQA V RTALAILTEGVVAAPLEGIA RVR IKRNFD KSN YLAVY Y AGPIRSAGGTA Q AL S VL VA DY 157
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 161 I R ISLE LD T YKP VDT EIERYVEEVELY E SEV T NLQY S P KPE E V R K AV K NIP V E V TGEPTD KI EVS - HRDL E RVETN NI RG 239
Cdd:TIGR00354 158 V R RAAG LD R YKP TEE EIERYVEEVELY K SEV A NLQY L P SDD E I R L AV S NIP I E I TGEPTD SV EVS g HRDL P RVETN RV RG 237
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 240 GALL A I A EGV IQ KAPK VM K YAKK L K I D GWDWL GEFS -- K APDPNADDSDAAP K VD DKY MR DII G GRPV M A Y P QA KGGFRL 317
Cdd:TIGR00354 238 GALL V I V EGV AL KAPK LL K MVDE L G I E GWDWL DALI kg K GDKGSEGEEKVVI K AK DKY LS DII A GRPV L A H P SR KGGFRL 317
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 318 RYGR S RN A G L A AM GVHP S TM EIV EF L AVGTQ M K I ERPGK GN CVVP C D S IEGP I VKLK D G S V VKVESEQQ AK KIKYQ VEEI 397
Cdd:TIGR00354 318 RYGR A RN T G F A TV GVHP A TM YLL EF V AVGTQ L K V ERPGK AG CVVP V D T IEGP T VKLK N G D V IRINTLEE AK AVRGE VEEI 397
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 398 V FLGD M LV PF G E FL R NNH IML PA G WC S EWW V Q TIQ K SESYQESD l D IKSLET E K idakt A FEISEKYD VPLHP D YTY CY H 477
Cdd:TIGR00354 398 L FLGD I LV NY G D FL E NNH PLI PA S WC E EWW I Q EAE K ANLSYLRG - D YRKISE E E ----- A LKLCDEFH VPLHP R YTY LW H 471
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 478 DV TTQ D INE L IQFINREL K T s DDPDL K AVSERIY D egsgglklpi S PE KRILE V LG IP H EIDGDELI I SRE ---- DAYV L 553
Cdd:TIGR00354 472 DV SVE D YRY L RNWLSDNG K L - EGKHG K SDLLLPE D ---------- S RV KRILE A LG LE H KVRESFVV I ETW rafi RCLG L 540
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 554 LNT L NRPV E T e GSNT LE A VN S I A P VQIMA KA PT Y L GAR V GRPEK S KERKM K P A PH A LFPIG TN GGN R R N I ID A AKKG - T I 632
Cdd:TIGR00354 541 DEK L SKVL E V - SKDV LE I VN G I S P IKVRP KA LS Y I GAR M GRPEK A KERKM S P P PH I LFPIG MA GGN T R D I KN A INYT k E I 619
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 633 N V D IA RC KC TE CG VG S MQAL CPVCG AR TE PTSS GK KRIN L AN L LKK A YE N V G VR K I D E IKGV V GM I S ED K F PEPLEKGIL 712
Cdd:TIGR00354 620 E V E IA IR KC PQ CG KE S FWLK CPVCG EL TE QLYY GK RKVD L RE L YEE A IA N L G EY K F D T IKGV K GM T S KT K I PEPLEKGIL 699
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 713 RAKN D V FT FKD A T I R H D S T N LP L THF I P S EIGV TPQ KL L ELGY TN D IH G DKIE D PD QIVE I K I QDV VVS E N C GD YL I RV S 792
Cdd:TIGR00354 700 RAKN G V YV FKD G T A R F D A T D LP I THF K P A EIGV SVE KL R ELGY ER D YY G AELK D EN QIVE L K P QDV IIP E S C AE YL V RV A 779
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 793 H F V DDLLE QL Y GL ERFYNV QTR EDL V G Q LV V GLAPHTSAGVLGRI V GFT K A ACC YAHPYFH S AKRRNCD S DEDS I MLLLD 872
Cdd:TIGR00354 780 N F I DDLLE KF Y KM ERFYNV KSV EDL I G H LV I GLAPHTSAGVLGRI I GFT D A LAG YAHPYFH A AKRRNCD G DEDS F MLLLD 859
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 873 ALLNFSK VY LP ST RGG K MDAPLVL SSRI DP E E I D D E S HN I D A M PYI PLE L YE K T LD F EK P SD V L D L V DN V KR RLG TED QY 952
Cdd:TIGR00354 860 ALLNFSK KF LP DK RGG Q MDAPLVL TTIV DP R E V D K E V HN M D T M ERY PLE F YE A T MR F PS P KE V E D Y V EK V ED RLG KPE QY 939
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 953 Q GL IYS H T TS S I HS GPKVC L YK T L P TM K EKV DG Q IK LA ER IRAVD QKG V V E G V LT SHFLPD MA GN S RAFSRQ K VRCTKC G 1032
Cdd:TIGR00354 940 C GL FFT H D TS R I DA GPKVC A YK S L K TM Q EKV YS Q ME LA RK IRAVD ERD V A E R V IN SHFLPD II GN L RAFSRQ E VRCTKC N 1019
1050 1060 1070 1080 1090 1100 1110
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 325331683 1033 R KYRRIPL S G N C - S CG S NL I L SI SKGSV V KYLE I SK N L SQR Y PIDE Y LV QR IELI E TS INS L FE SDK SKQ S SL DV F 1107
Cdd:TIGR00354 1020 T KYRRIPL V G K C l K CG N NL T L TV SKGSV M KYLE L SK F L AEN Y NVSS Y TK QR LMIL E QG INS M FE NGT SKQ V SL SD F 1095
PRK14714
PRK14714 DNA-directed DNA polymerase II large subunit;
3-1108
0e+00
DNA-directed DNA polymerase II large subunit;
Pssm-ID: 237798 [Multi-domain]
Cd Length: 1337
Bit Score: 1484.56
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 3 YFE V LE K E TL K L YE I A KS AR SK G H D IEL E P EIP L A K D L A E RVE G L V G PK GVA A RI K ELE TDI SREE V A FQ I AREI V tdtd 82
Cdd:PRK14714 10 YFE R LE R E LD K A YE V A EA AR AR G L D PSP E V EIP I A R D M A D RVE N L L G ID GVA E RI R ELE GEM SREE A A LK I VDDF V ---- 85
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 83 v EG RDDTLEVR E Q K SDQ A I RTA L A I LTEGVVAAP L EGIA KLK IK R N F D SGY YLAVY F AGPIRSAGGTA A AL A VL I GDY I R 162
Cdd:PRK14714 86 - EG KFGDYDTK E G K AEG A V RTA V A L LTEGVVAAP I EGIA RVE IK K N D D GTE YLAVY Y AGPIRSAGGTA Q AL S VL V GDY V R 164
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 163 IS L EL D T YKP VDT EIERY V EE VE LY E SE VT n LQYSP KPE E V R KAVK N I P VEVT GE P T DKI EVS - HRDLERVETN NI RGG A 241
Cdd:PRK14714 165 AK L GI D R YKP REE EIERY A EE ID LY D SE TG - LQYSP SEK E I R LIAE N C P IMID GE A T GDE EVS g HRDLERVETN SL RGG M 243
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 242 L L AI AEG VIQ KAPK VM KY AK K L K ID GWDWL G E F ------ S K APDPNADDSD ------------- AAPKVD DKY M RD I IGG 302
Cdd:PRK14714 244 C L VL AEG IAL KAPK IQ KY TR K M K EE GWDWL Q E L idgtie G K SDAGEEGEEE elstdadeyekgp PRIAPS DKY L RD L IGG 323
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 303 RPV MAY P QAK GGFRLRYGRSRN A G L A AM GVHP S TM EI V - E FLAVGTQMK I ERPGK GNC VVP C D S IEGP I VKL KD G S V VK V 381
Cdd:PRK14714 324 RPV FSH P SRN GGFRLRYGRSRN T G F A TA GVHP A TM HL V d D FLAVGTQMK T ERPGK AAG VVP V D T IEGP T VKL AN G D V RR V 403
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 382 ESEQQ A KKIKYQ VEEI VFL G DM LV PF GEF LR NNH IM LPA GW C S EWW V Q TIQ K SESYQESDL D IKSLETEKIDAKT A FEIS 461
Cdd:PRK14714 404 DDPEE A LEVRNG VEEI LDV G EY LV NY GEF VE NNH PL LPA SY C E EWW I Q ELV K AGADVQALE D KPFVDLTRPTVEE A AHWA 483
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 462 EK Y DV PLHP D YTY CY HD VTTQDINE L IQFI nrelktsddpd LK A VSER I YDEGS G G L K LP IS P E - KR I LE V L GI PH EIDG 540
Cdd:PRK14714 484 TE Y GA PLHP Y YTY LW HD ISVEQVRA L ADAV ----------- AD A ETRG I GFADD G V L V LP LT P T v KR T LE L L LV PH TVRE 552
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 541 D ELI I sr E D AYV LL NT L NRPV ----------- ETE G S N TLEAV N SI AP VQIMAK APT YL G A R V GRPEKSK E RKMKP AP H A 609
Cdd:PRK14714 553 D RIR I -- P D WRP LL RS L GLDL sseaalewefa PKD G H N AIDLI N EL AP FKVRER APT RI G N R M GRPEKSK P RKMKP PV H T 630
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 610 LFPIG TN GG NR R NIID AAK K -------- G T I N V DIA R CK C TE CG VGSMQAL CP V CG AR TEP ------------------- 662
Cdd:PRK14714 631 LFPIG EA GG AQ R DVAK AAK H apdmsdeg G V I E V EVG R RR C PS CG TETYENR CP D CG TH TEP vyvcpdcgaevppdesgrv 710
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 663 --------- T SSGKKR IN LANLLKK A Y ENVG V R K -- I D EI KGV V G MI S ED K F PEPLEKGILRAK N DV FT FKD A T I R H D S T 731
Cdd:PRK14714 711 ecprcdvel T PYQRRT IN VKEEYRS A L ENVG E R E na F D LL KGV K G LT S RE K I PEPLEKGILRAK H DV YV FKD G T V R Y D M T 790
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 732 N LP L THF I P S EIGV TPQ KL L ELGYT N DIHGD KIEDP DQ I VE I K I QD V V V S ENCGD YL IR V SH FVDDLLE QL YGL E RFYNV 811
Cdd:PRK14714 791 D LP V THF R P R EIGV SVE KL R ELGYT Q DIHGD PLVHE DQ V VE L K V QD I V L S DGAAE YL LK V AK FVDDLLE KF YGL P RFYNV 870
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 812 QT REDLVG Q LV V GLAPHTSAGV L GRI V GFT K A ACC YAHPYFH S AKRRN -------------------------------- 859
Cdd:PRK14714 871 EK REDLVG H LV I GLAPHTSAGV V GRI I GFT S A NVG YAHPYFH A AKRRN cfhgdtrilvqddggwhrdpirifveerldle 950
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 --------------------------------------------------------------------------------
Cdd:PRK14714 951 dpgyddfgtvyqkpkrdvkvysvdengkvvltditsvskhpapdhlirfetergrsltvtpdhamlvwdggylekkrafe 1030
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 860 --------------------------------------------------------- CD S DED SI MLLLD A LLNFSK VY L 882
Cdd:PRK14714 1031 vkegdavpvpegveetgvvladevvsieyvesdddfvycltvaeyhtvvangiftgq CD G DED CV MLLLD G LLNFSK SF L 1110
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 883 P ST RGGKMDAPLVL S SRIDP E EIDDE S HN I D AMP Y I PLE L YE K TL DFEK P S DV L DL VDN V KR RLGT ED QY Q G LIYS H T TS 962
Cdd:PRK14714 1111 P EK RGGKMDAPLVL T SRIDP S EIDDE A HN M D VVR Y Y PLE F YE A TL EMAD P K DV E DL IER V ED RLGT PE QY E G FGFT H D TS 1190
1210 1220 1230 1240 1250 1260 1270 1280
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 963 S I HS GPK VCL YKTL PT M KE K V D G Q IK LA ER IRAVD QKG V V E G V LTS HF L PD MA GN S RAFSRQ KV RC T KCG R KYRR I PL S G 1042
Cdd:PRK14714 1191 D I AL GPK LSA YKTL GS M LD K M D A Q LE LA RK IRAVD EHD V A E R V INY HF I PD LI GN L RAFSRQ EF RC L KCG T KYRR M PL A G 1270
1290 1300 1310 1320 1330 1340
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 325331683 1043 N C S - CG SNL IL SISK GSV V KYL EIS K NLSQR Y PID EY LV QR I E LIETS I N SLFE S DK S KQS S L DV F L 1108
Cdd:PRK14714 1271 K C R k CG GRI IL TVHE GSV E KYL DTA K MVATE Y NVR EY TK QR L E VLDRD I E SLFE N DK N KQS G L AD F M 1337
PolC_DP2
pfam03833 DNA polymerase II large subunit DP2;
3-859
0e+00
DNA polymerase II large subunit DP2;
Pssm-ID: 427537
Cd Length: 866
Bit Score: 1364.91
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 3 YFE V LEKE TLKL YEIA KS ARS K G H D IEL E P EIPLAKDLA E RVE G L V G P KGVA A RI K ELE TDI SREE V A FQ IA R EI V tdtd 82
Cdd:pfam03833 2 YFE R LEKE LDEA YEIA EK ARS R G L D PSP E V EIPLAKDLA D RVE K L L G I KGVA E RI R ELE KTM SREE A A LE IA K EI A ---- 77
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 83 v EG RDDTLEVR E QKS DQA I RTALAILTEGVVAAPLEGIA KL KIK R N F D SGY YL A VY F AGPIRSAGGTA A AL A VL IG DY I R 162
Cdd:pfam03833 78 - EG KVGDFDSK E EAL DQA V RTALAILTEGVVAAPLEGIA RV KIK K N D D GTE YL S VY Y AGPIRSAGGTA Q AL S VL VA DY V R 156
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 163 IS L EL D T YKP V D T EIERYVEE V ELY ES e VT N LQYSP KP EE V R KA V K N I PV EVT GEPT DKI EVS - HRDLERVETN NI RGG A 241
Cdd:pfam03833 157 RL L GI D R YKP R D E EIERYVEE I ELY KR - VT H LQYSP SD EE I R LI V R N C PV CID GEPT EDE EVS g HRDLERVETN RV RGG M 235
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 242 L L AI AEG VIQ KAPK VM K YA KKL K IDGW D WL G E F --- S KA PDPNADDSDAAP K VD DKY M RD I I G GRPV MAY P QAK GGFRLR 318
Cdd:pfam03833 236 C L VL AEG IAL KAPK IL K HV KKL G IDGW E WL D E L ikg D KA EKTGEEEEKPRV K PK DKY L RD L I A GRPV FSH P SRP GGFRLR 315
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 319 YGRSRN A G L A AM G V HP S TM E I V - E F L AVGTQ M K I ERPGK GNC VVP C DSIEGP I V K LK D G S VV KVESEQQ A KK I KYQ VEEI 397
Cdd:pfam03833 316 YGRSRN T G F A TA G I HP A TM H I L d D F I AVGTQ L K V ERPGK AAG VVP V DSIEGP T V R LK N G D VV RIDDVEE A LE I RND VEEI 395
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 398 VF LG DM L VPF G E FL R NNH IML P AGW C S EWW V Q TIQKSESYQESD ldikslet E KID A KT A F EIS EK Y D VPLHPDYTY CY H 477
Cdd:pfam03833 396 LD LG EI L INY G D FL E NNH PLV P SSY C E EWW I Q ELEAAGADVQAL -------- E DPT A EE A L EIS KE Y G VPLHPDYTY LW H 467
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 478 D VTTQDI N E L IQFINREL K TS ddpdlkavseriydegs G G L K LP IS PE - KRILE V L GI PH EIDGDEL II sr E D A Y V LL NT 556
Cdd:pfam03833 468 D ISVEEL N A L ADAVAKGG K IG ----------------- G V L V LP LD PE i KRILE K L LV PH KVRDGKI II -- D D W Y P LL RC 528
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 557 L NRPVET ------ E GSNT LEAVN SIAPVQIM A K APT YL GAR V GRPEKSKERKMKP AP H A LFPIG TN GG N RR N I ID AAK -- 628
Cdd:pfam03833 529 L GLDEDL gklske E RKDA LEAVN ELSGFKVR A R APT RI GAR M GRPEKSKERKMKP PV H V LFPIG EA GG S RR D I AE AAK ya 608
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 629 -- KG T I N V D I A R CK C TE CG VGSMQAL CP V CGA R TEP ----------------------- T SSG K KR I N L ANLLKK A Y EN V 683
Cdd:pfam03833 609 en KG E I E V E I G R RR C PN CG KETFENR CP D CGA H TEP vyvcpkcgievedekcpkcgrea T CVS K IK I D L KKEYRR A L EN L 688
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 684 G V R -- KI DE I KGV V G MI S E DK F PEPLEKGILRAK ND V FT FKD A T I R H D S T N LPLTHF I P S EIGV TPQ KL L ELGYT N DI H G 761
Cdd:pfam03833 689 G E R en AL DE L KGV K G LT S K DK T PEPLEKGILRAK HG V SV FKD G T V R Y D M T D LPLTHF R P R EIGV SVE KL R ELGYT H DI Y G 768
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 762 DKI E DP DQIVE I K I QD VVV SE NCGD YL IR V SH F V DDLLE QL YGLE R FYNV QT REDL V G Q LV V GLAPHTSAGVLGRI V GFT 841
Cdd:pfam03833 769 KPL E SE DQIVE L K V QD IIL SE DAAE YL LK V AK F I DDLLE KY YGLE P FYNV ED REDL I G H LV I GLAPHTSAGVLGRI I GFT 848
890
....*....|....*...
gi 325331683 842 KA ACC YAHPYFH S AKRRN 859
Cdd:pfam03833 849 KA SVG YAHPYFH A AKRRN 866
PRK14715
PRK14715 DNA-directed DNA polymerase II large subunit;
3-874
0e+00
DNA-directed DNA polymerase II large subunit;
Pssm-ID: 237799 [Multi-domain]
Cd Length: 1627
Bit Score: 971.63
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 3 YFE VLEK E TLKL Y E IA KSA R S KG H D IELEP EIPLA K D L A E RVEGLVGPKGVA A RI K EL ETDISR E EV A FQI A R EIV tdtd 82
Cdd:PRK14715 13 YFE NIQR E VDRI Y K IA EKC R A KG K D PSDDV EIPLA T D M A D RVEGLVGPKGVA E RI R EL VKELGK E PA A LEV A K EIV ---- 88
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 83 v EG RDDT L E v R E QKSD QA I RTALAILTEG V VAAPLEGIA KL KIKRN F D SGY YLA V Y F AGPIRSAGGTA A AL A VL I GDY I R 162
Cdd:PRK14715 89 - EG KFGD L S - K E KYAE QA V RTALAILTEG I VAAPLEGIA DV KIKRN E D GSE YLA I Y Y AGPIRSAGGTA Q AL S VL V GDY V R 166
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 163 ISLE LD T YKP VDT EIERYVEEV E LY E SEV TNL QYSP KPE E V R K A VK NIP V E V TGE P TD KI EVS - HRDL E RVETN NI RGGA 241
Cdd:PRK14715 167 KKMG LD R YKP SED EIERYVEEV D LY Q SEV GRF QYSP EAD E I R T A MR NIP I E I TGE E TD DV EVS g HRDL P RVETN HL RGGA 246
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 242 LL AIA EGV IQ KAPK VMKYAK KL K I D GWDWL G E FSKA ------- PDPNADDSDAAPKVDD ------------------- K Y 295
Cdd:PRK14715 247 LL VLV EGV LL KAPK ILRHVD KL G I E GWDWL K E LKEK keekdee KSEEVKTEEVDEEFEE eekgfyyelyekvnieank K F 326
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 296 MRDI I G GRPV M A Y P QAK GGFRLRYGRSRN A G L A AM G V HP ST M EI V - EF L A V GTQ M K I ERPGK GN CVVP C DSIE G PIVKLK 374
Cdd:PRK14715 327 IKEV I A GRPV F A H P STN GGFRLRYGRSRN T G F A TW G F HP AL M YL V d EF M A I GTQ L K T ERPGK AT CVVP V DSIE P PIVKLK 406
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 375 D GSVV K V ESEQQ A KKIKYQ VEEI V FLGD M LV PF G E FL R NNH IM LP AG WC S EW WV Q T - I Q K SES Y QESDL dikslet EKID 453
Cdd:PRK14715 407 N GSVV R V DTIEK A IEVRNR VEEI L FLGD A LV NY G D FL E NNH TL LP SN WC E EW YE Q E l I A K NIE Y DPEFI ------- NNPT 479
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 454 AKT A FEISEKY D V PLHP D YTY CY HDV TTQD I NE L IQFI nrelktsddpd L KA v S E RIYDEGSGGLKLPISP E ----- KRI 528
Cdd:PRK14715 480 PEE A IHFALVT D T PLHP R YTY YW HDV SKEE I EL L RKWL ----------- L GG - K E EWFEGKKNVWAVKVVL E ddkki KRI 547
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 529 LE VL G I PH EIDGD E L --- I I SR E DA Y V LL NT L NRPV E TEGS ------------- N TLEAV N SIAPVQIMAKAPT Y L GAR V 592
Cdd:PRK14715 548 LE LI G C PH RVERS E N rnk V I VI E EY Y P LL YS L GTDL E NLKD lvqnweekakpfk N VIHFI N LLSRFELRRRGYS Y I GAR M 627
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 593 GRPEK SKE RKMKP APHA LFPIG TN GG NR R N I ID A AKKG - T INVD IA RC KC TE CG VGSMQAL CP V CG A R T E PTSSGKKR I N 671
Cdd:PRK14715 628 GRPEK AAP RKMKP PVNV LFPIG NA GG QV R L I NK A VEEN k T DDIE IA FF KC PK CG KVGLYHV CP F CG T R V E LKPYARRE I P 707
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 672 LANLLKK A Y EN VGVR K IDEI K GVV GM I S ED K FP EPLEKGILRAKNDV FT FKD A TIR H D S T NL P L THF I PSEI G V TPQ KL L 751
Cdd:PRK14715 708 PKDYWYA A L EN LKIN K PGDV K CIK GM T S KY K IV EPLEKGILRAKNDV YV FKD G TIR F D C T DV P I THF K PSEI N V SVE KL R 787
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 752 ELGY TN DI H G DKI E DP DQI V E I K I QDV VVSE NC GD Y LIR V SH F V DDLLE QL Y G L E RFYNV QTR EDL V G Q LV V G L APHTSA 831
Cdd:PRK14715 788 ELGY DK DI E G KPL E RD DQI L E L K V QDV IIPY NC AE Y FLK V AR F I DDLLE KF Y K L D RFYNV KKK EDL I G H LV I G M APHTSA 867
890 900 910 920
....*....|....*....|....*....|....*....|...
gi 325331683 832 G VL GRI V G FTK A ACC YAHPYFH S AKRRNC DSDEDS I MLLL D AL 874
Cdd:PRK14715 868 G MV GRI I G YSD A LVG YAHPYFH A AKRRNC FPGDTR I LVNI D GN 910
PolC
COG1933 Archaeal DNA polymerase II, large subunit [Replication, recombination and repair];
40-1107
0e+00
Archaeal DNA polymerase II, large subunit [Replication, recombination and repair];
Pssm-ID: 441536 [Multi-domain]
Cd Length: 1075
Bit Score: 940.46
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 40 LA E RVEGLV G PKGV AA RIKELETDIS R EEV A FQIAREIVTDTDVEGRDDT LE VRE qks D QAIRTALAI LTEGVVAA PLE G 119
Cdd:COG1933 7 EL E EELAEE G EEEI AA ELGAERAGEA R AGL A AELEAKVRAVLKLLEAAAA LE AGI --- D AEAGAGALA LTEGVVAA AGQ G 83
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 120 IAKLK IK RNFDSGYYLAVYFA G PIRSAG G TA A ALAV L I G DYI R IS LE LDT Y -- KPVDT E IE R YV E EVELY E SEVTNLQ - Y 196
Cdd:COG1933 84 AEAAA IK AAGGGAVEGSIVRR G GGGRVR G GE A EEEA L A G EVR R KV LE IED Y dr LSEVD E EV R EE E LLLAE E EDEEEEE e E 163
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 197 SPKP EE VRKAVKNIPV E VTGEPTDKIE V SHRDLERVETNNIR G GA LL AIAE G VIQKAPKVMKYAK K LKIDGWDW L GEFSK 276
Cdd:COG1933 164 EVED EE ADEVEEDDEE E GGLGLELRAL V LVVGRDLKADKAEG G NV LL TDLD G EGEEGEDDEGDEG K DEDGEEAV L RDEGG 243
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 277 A P DPNADDSDAAPKVDD K YMRDIIGGRPVMAYPQAKGGFRLRYGRSRNA G L A AM G VH PS TMEI V EFLA V GTQMKIERPGK 356
Cdd:COG1933 244 G P LEPLVGGRVGDLARE K GGTLAALVAGGGRILAGLLLGDGAVTLGEAL G V A VV G GA PS EGGG V GLEG V VVVLRGGSLVV 323
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 357 GNC V VPCDSIEGPIVKLKDGSVVKVESEQQAKKIKYQVEEIVFLGDMLVPFG E FLRNNHIMLPAGWCS E WWVQTIQKS ES 436
Cdd:COG1933 324 LGV V AAVKITGRVEEEIVVKEEDDLDEREIDLDDELLGPGEPEELLVAELLE E PDGEELSGEVEEEEE E LDELEEEAE ES 403
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 437 YQ E S D L D IKS L ETEKI DA KTAFEIS E KYDVP L HPDYTYCYHDVTTQDIN EL IQFINRELKTSDDPD L KAVS E RIYDEGSG 516
Cdd:COG1933 404 RE E G D E D EEE L TEREE DA LSLKLEL E RELEG L LTEEEEELLELLEELLL EL LDEELEDELILELLI L LEEE E EEELILDL 483
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 517 G L K L PI S PE K RI L EV L GIPHEIDG D ELIISREDAYVLLNTLN R PVETEG S NTLEAVNSIAP V QIMAKAPTY LG ARVGRPE 596
Cdd:COG1933 484 L L E L DL S EL K KG L KL L SDREVAPF D LESGGLVALKSRMVRPR R RERRDL S DRRRTLEPAGE V GPPIGDVGL LG RGLRGAA 563
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 597 KSKERKMKPAPHALF PI GTNGGNRRNIIDAAKKGTINVDIAR C KCTE C GVG S MQAL CP V CG ART EP TS S GK K RIN L ANL L 676
Cdd:COG1933 564 DTDLKEAAGVGLFKE PI LRLECCECGEPSCEICIECGLEKPY C LICC C PDE S GRDE CP C CG CGR EP ST S SR K DFP L KKR L 643
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 677 KK A Y EN VGV R KI D EI KGV V G MI S E DK F PEPLEKGILRAK N DV FT FKD A T I R H D S T N LPLTHF I PSEIGVT PQ KL L ELGYT 756
Cdd:COG1933 644 AA A E EN GRE R AL D PL KGV K G LT S R DK T PEPLEKGILRAK H DV SV FKD G T V R Y D M T D LPLTHF R PSEIGVT VE KL R ELGYT 723
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 757 N DI H G DKI E DP DQ I VE I K I QD VVV SE NCGD YL I RV SH F V DDLLE QL YGLE R FYN VQT REDL V G Q LV V GLAPHTSAGV L GR 836
Cdd:COG1933 724 E DI L G KPL E SE DQ L VE L K V QD III SE DAAE YL L RV AK F I DDLLE KY YGLE P FYN AED REDL I G H LV I GLAPHTSAGV V GR 803
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 837 I V GFT K A ACC YAHPYFH S AKRRNCD S DED SI MLLLD A LLNFS KVY LP ST RGG K MDAPLVL S SRIDP E EIDDE S HN I D AMP 916
Cdd:COG1933 804 I I GFT L A VVG YAHPYFH A AKRRNCD G DED CV MLLLD G LLNFS RSF LP DK RGG L MDAPLVL T SRIDP S EIDDE A HN M D VVS 883
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 917 YI PLE L YE K TL DFEK P SD V L DL V D N V KR RLGT ED QY Q G LIYS H T TS S I HS GP KVCL YKTL PT M KE K V D G Q IK LA ER IRAV 996
Cdd:COG1933 884 RY PLE F YE A TL EMAD P KE V E DL I D I V ED RLGT DG QY E G FGFT H D TS D I AA GP DLSA YKTL GS M MD K M D A Q LE LA RK IRAV 963
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 997 D QKG V V E G V LT SHFLPD MA GN S RAFSRQ KV RC T KCG R KYRR I PL S G N C - S CG S N L IL SISK GSV V KYLE IS K NLSQR Y PI 1075
Cdd:COG1933 964 D ETD V A E R V IE SHFLPD LI GN L RAFSRQ EF RC L KCG A KYRR M PL T G K C r K CG G N V IL TVHE GSV N KYLE TA K KVAEE Y DV 1043
1050 1060 1070
....*....|....*....|....*....|..
gi 325331683 1076 DE Y LV QR I E LI E T SI N SLFE S DK S KQS S L DV F 1107
Cdd:COG1933 1044 RD Y TK QR L E IL E R SI E SLFE N DK N KQS G L AD F 1075
PRK14715
PRK14715 DNA-directed DNA polymerase II large subunit;
859-1107
2.25e-93
DNA-directed DNA polymerase II large subunit;
Pssm-ID: 237799 [Multi-domain]
Cd Length: 1627
Bit Score: 328.34
E-value: 2.25e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 859 N CD S DED SIM LLLDA L LNFSK VY LP ST RGG K MDAPLVL SS R I DP E E I D D E S HN I D A M P Y I PLE L YEKTL DFEK P SD V LDL 938
Cdd:PRK14715 1376 Q CD G DED AVF LLLDA F LNFSK YF LP DK RGG Q MDAPLVL TT R L DP K E V D G E V HN M D T M W Y Y PLE F YEKTL EMPS P KE V KEF 1455
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 939 VDN V KR RLG TED QY Q G LI Y S H T T SS I HS GPK V C L YKTL PT M K EK VDG Q IKL AE R IRA V D QKG V V E G V LT SHF L PD MA GN S 1018
Cdd:PRK14715 1456 IET V ED RLG KPE QY E G IG Y T H E T DD I GL GPK I C A YKTL GS M L EK TAR Q LAV AE K IRA T D ERD V A E K V IQ SHF V PD LI GN L 1535
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325331683 1019 RAFSRQ KV RC t KCG R KYRR I PL S G N C - S CGS N LIL SI SKG S V V KY LEIS K NLSQR Y PIDE Y LV QR IEL I ETS I N SLFE S D 1097
Cdd:PRK14715 1536 RAFSRQ EF RC - KCG A KYRR V PL K G K C p K CGS K LIL TV SKG A V E KY MPVA K MMAEK Y NVND Y TK QR LCI I KEG I K SLFE N D 1614
250
....*....|
gi 325331683 1098 K S KQ SS LD V F 1107
Cdd:PRK14715 1615 K R KQ VK LD D F 1624
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
