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Conserved domains on  [gi|410066324|gb|AFV57850|]
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ATP synthase F0 subunit 6, partial (mitochondrion) [Leiopotherapon unicolor]

Protein Classification

ATP synthase F0 subunit 6( domain architecture ID 10009577)

ATP synthase F0 subunit 6 is part of the mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V), which produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ATP6 MTH00132
ATP synthase F0 subunit 6; Provisional
 1-193 1.69e-118

ATP synthase F0 subunit 6; Provisional


:

Pssm-ID: 177190  Cd Length: 227  Bit Score: 334.92  E-value: 1.69e-118
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 410066324   1 MTLSFFDQFMSPSLLGIPLMALALTLPWTLFPTPTPRWLHSRMLALQSWFINRFAQELLLPLSPAGHKWAMLFTSLMLYL 80
Cdd:MTH00132   1 MTLSFFDQFMSPTYLGIPLIALALTLPWILFPTPTSRWLNNRLLTLQGWFINRFTQQLLLPLNVGGHKWALLLTSLMLFL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 410066324  81 ISLNMLGLLPYTFTPTTQLSLNLGLAVPLWLATVIIGMRNQPTIALGHLLPEGTPTPLIPVLIIIETISLFIRPIALGVR 160
Cdd:MTH00132  81 ITLNMLGLLPYTFTPTTQLSLNMGLAVPLWLATVIIGMRNQPTHALGHLLPEGTPTPLIPVLIIIETISLFIRPLALGVR 160

                        170       180       190
                 ....*....|....*....|....*....|...
gi 410066324 161 LTANLTAGHLLIQLIATAAFVLLPLMPTVAILT 193
Cdd:MTH00132 161 LTANLTAGHLLIQLIATAAFVLLPLMPTVAILT 193
 
Name Accession Description Interval E-value
ATP6 MTH00132
ATP synthase F0 subunit 6; Provisional
 1-193 1.69e-118

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177190  Cd Length: 227  Bit Score: 334.92  E-value: 1.69e-118
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 410066324   1 MTLSFFDQFMSPSLLGIPLMALALTLPWTLFPTPTPRWLHSRMLALQSWFINRFAQELLLPLSPAGHKWAMLFTSLMLYL 80
Cdd:MTH00132   1 MTLSFFDQFMSPTYLGIPLIALALTLPWILFPTPTSRWLNNRLLTLQGWFINRFTQQLLLPLNVGGHKWALLLTSLMLFL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 410066324  81 ISLNMLGLLPYTFTPTTQLSLNLGLAVPLWLATVIIGMRNQPTIALGHLLPEGTPTPLIPVLIIIETISLFIRPIALGVR 160
Cdd:MTH00132  81 ITLNMLGLLPYTFTPTTQLSLNMGLAVPLWLATVIIGMRNQPTHALGHLLPEGTPTPLIPVLIIIETISLFIRPLALGVR 160

                        170       180       190
                 ....*....|....*....|....*....|...
gi 410066324 161 LTANLTAGHLLIQLIATAAFVLLPLMPTVAILT 193
Cdd:MTH00132 161 LTANLTAGHLLIQLIATAAFVLLPLMPTVAILT 193
ATP_synt_6_or_A TIGR01131
ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Bacterial forms should be ...
 4-193 9.76e-40

ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Bacterial forms should be designated ATP synthase, F0 subunit A; eukaryotic (chloroplast and mitochondrial) forms should be designated ATP synthase, F0 subunit 6. The F1/F0 ATP synthase is a multisubunit, membrane associated enzyme found in bacteria and mitochondria and chloroplast. This enzyme is principally involved in the synthesis of ATP from ADP and inorganic phosphate by coupling the energy derived from the proton electrochemical gradient across the biological membrane. A brief description of this multisubunit enzyme complex: F1 and F0 represent two major clusters of subunits. Individual subunits in each of these clusters are named differently in prokaryotes and in organelles e.g., mitochondria and chloroplast. The bacterial equivalent of subunit 6 is named subunit 'A'. It has been shown that proton is conducted though this subunit. Typically, deprotonation and reprotonation of the acidic amino acid side-chains are implicated in the process. [Energy metabolism, ATP-proton motive force interconversion]


Pssm-ID: 273458  Cd Length: 226  Bit Score: 135.03  E-value: 9.76e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 410066324    4 SFFDQFMSPSLLGIPLMALALTLPWTLFPTPTPRWL-HSRMLALQSWFINRFAQELLLPLSPAGHKWAMLFTSLMLYLIS 82
Cdd:TIGR01131   4 QFDISPITLFSLTLLSLILLLSLLIFLISSSLSRWLiPSRWQNLMESIYEFVLSIVKSQIGGKKGKFFPLIFTLFLFILI 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 410066324   83 LNMLGLLPYTFTPTTQLSLNLGLAVPLWLATVIIGMRNQPTIALGHLLPEGTPTPLIPVLIIIETISLFIRPIALGVRLT 162
Cdd:TIGR01131  84 SNLLGLIPYSFTPTSHLSFTLGLALPLWLGLTISGFRKHPKGFLAHLVPSGTPLPLIPFLVIIETISYLARPISLSVRLF 163

                         170       180       190
                  ....*....|....*....|....*....|.
gi 410066324  163 ANLTAGHLLIQLIATAAFVLLPLMPTVAILT 193
Cdd:TIGR01131 164 ANISAGHLLLTLLSGLLFSLMSSAIFALLLL 194
ATP-synt_Fo_a_6 cd00310
ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms ...
 66-192 3.16e-31

ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms are designated as ATP synthase, Fo complex, subunit a; eukaryotic (chloroplast and mitochondrial) forms are designated as ATP synthase, Fo complex, subunit 6. The F-ATP synthases (also called FoF1-ATPases) consist of two structural domains: F1 (factor one) complex containing the soluble catalytic core, and Fo (oligomycin sensitive factor) complex containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. F-ATP synthases are primarily found in the inner membranes of eukaryotic mitochondria, in the thylakoid membranes of chloroplasts or in the plasma membranes of bacteria. F-ATP synthase has also been found in the archaea Methanosarcina acetivorans. F-ATP synthases are the primary producers of ATP, using the proton gradient generated by oxidative phosphorylation (mitochondria) or photosynthesis (chloroplasts). Alternatively, under conditions of low driving force, ATP synthases function as ATPases, thus generating a transmembrane proton or Na(+) gradient at the expense of energy derived from ATP hydrolysis.


Pssm-ID: 349411 [Multi-domain]  Cd Length: 156  Bit Score: 110.95  E-value: 3.16e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 410066324  66 GHKWAMLFTSLMLYLISLNMLGLLPYTFTPTTQLSLNLGLAVPLWLATVIIGMRNQPTIALGHLLPEGTPTPLIPVLIII 145
Cdd:cd00310    1 GKKYLPLLGTLFLFILFSNLLGLIPYSFTPTSHLNVTLALALIVFLGVHILGIKKHGLGFFLHFLPPGTPLPLAPLMVPI 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 410066324 146 ETISLFIRPIALGVRLTANLTAGHLLIQLIATAAFVLLPLMPTVAIL 192
Cdd:cd00310   81 ELISELIRPLSLSVRLFANMFAGHLLLALLSGLVPSLLSSVGLLPLL 127
ATP-synt_A pfam00119
ATP synthase A chain;
66-193 2.90e-25

ATP synthase A chain;


Pssm-ID: 459679 [Multi-domain]  Cd Length: 216  Bit Score: 97.18  E-value: 2.90e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 410066324   66 GHKWAMLFTSLMLYLISLNMLGLL---PYTFTPTTQLSLNLGLAVPLWLATVIIGMRNQPTIA-LGHLLPEGTPTPLIPV 141
Cdd:pfam00119  54 GRKFFPLLLTLFFFILVSNLLGLIpksPGGFTVTADINVTLALALIVFLLVHYYGIKKHGLGGyFKKLFVPPVPLPLVPL 133

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 410066324  142 LIIIETISLFIRPIALGVRLTANLTAGHLLIQLIATAAFVLLPLMPTVAILT 193
Cdd:pfam00119 134 LLPIEIISEFARPVSLSLRLFGNMLAGHLLLLLLAGLIFALLSAGFLLGVIP 185
AtpB COG0356
FoF1-type ATP synthase, membrane subunit a [Energy production and conversion]; FoF1-type ATP ...
 61-191 7.86e-19

FoF1-type ATP synthase, membrane subunit a [Energy production and conversion]; FoF1-type ATP synthase, membrane subunit a is part of the Pathway/BioSystem: FoF1-type ATP synthase


Pssm-ID: 440125 [Multi-domain]  Cd Length: 212  Bit Score: 80.12  E-value: 7.86e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 410066324  61 PLSPAGHKWAMLFTSLMLYLISLNMLGLLPYTFTPTTQLSLNLGLAVPLWLATVIIGMRNQPTIA-LGHLLPEGTPtPLI 139
Cdd:COG0356   49 TIGKKGRKFAPLLLTLFLFILVSNLLGLIPGLFPPTADINVTLALALIVFVLVHYYGIKKKGLGGyLKHLFFPPFP-WLA 127

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 410066324 140 PVLIIIETISLFIRPIALGVRLTANLTAGHLLIQLIATAAFVLLPLMPTVAI 191
Cdd:COG0356  128 PLMLPIEIISELARPLSLSLRLFGNMFAGHIILLLLAGLAPFLLLGVLSLLL 179
 
Name Accession Description Interval E-value
ATP6 MTH00132
ATP synthase F0 subunit 6; Provisional
 1-193 1.69e-118

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177190  Cd Length: 227  Bit Score: 334.92  E-value: 1.69e-118
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 410066324   1 MTLSFFDQFMSPSLLGIPLMALALTLPWTLFPTPTPRWLHSRMLALQSWFINRFAQELLLPLSPAGHKWAMLFTSLMLYL 80
Cdd:MTH00132   1 MTLSFFDQFMSPTYLGIPLIALALTLPWILFPTPTSRWLNNRLLTLQGWFINRFTQQLLLPLNVGGHKWALLLTSLMLFL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 410066324  81 ISLNMLGLLPYTFTPTTQLSLNLGLAVPLWLATVIIGMRNQPTIALGHLLPEGTPTPLIPVLIIIETISLFIRPIALGVR 160
Cdd:MTH00132  81 ITLNMLGLLPYTFTPTTQLSLNMGLAVPLWLATVIIGMRNQPTHALGHLLPEGTPTPLIPVLIIIETISLFIRPLALGVR 160

                        170       180       190
                 ....*....|....*....|....*....|...
gi 410066324 161 LTANLTAGHLLIQLIATAAFVLLPLMPTVAILT 193
Cdd:MTH00132 161 LTANLTAGHLLIQLIATAAFVLLPLMPTVAILT 193
ATP6 MTH00073
ATP synthase F0 subunit 6; Provisional
 1-193 8.11e-97

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177144  Cd Length: 227  Bit Score: 280.31  E-value: 8.11e-97
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 410066324   1 MTLSFFDQFMSPSLLGIPLMALALTLPWTLFPTPTPRWLHSRMLALQSWFINRFAQELLLPLSPAGHKWAMLFTSLMLYL 80
Cdd:MTH00073   1 MNLSFFDQFLSPTLLGIPLIMLAMLLPWLLFPTPTNKWLNNRLSTLQIWFLQNFTKQLMLPLNTPGHKWALILTSLMVFL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 410066324  81 ISLNMLGLLPYTFTPTTQLSLNLGLAVPLWLATVIIGMRNQPTIALGHLLPEGTPTPLIPVLIIIETISLFIRPIALGVR 160
Cdd:MTH00073  81 ITMNLLGLLPYTFTPTTQLSLNLGLAVPLWLATVLIGLRNQPTASLGHLLPEGTPTLLIPILIIIETISLFIRPLALGVR 160

                        170       180       190
                 ....*....|....*....|....*....|...
gi 410066324 161 LTANLTAGHLLIQLIATAAFVLLPLMPTVAILT 193
Cdd:MTH00073 161 LTANLTAGHLLIQLISTATLVLLPLMPTVSILT 193
ATP6 MTH00120
ATP synthase F0 subunit 6; Provisional
 1-193 2.39e-86

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177181  Cd Length: 227  Bit Score: 253.59  E-value: 2.39e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 410066324   1 MTLSFFDQFMSPSLLGIPLMALALTLPWTLFPTPTPRWLHSRMLALQSWFINRFAQELLLPLSPAGHKWAMLFTSLMLYL 80
Cdd:MTH00120   1 MNLNFFDQFSSPELLGIPLILLAMLIPALLIPSPKNRLLTNRLTTLQLWLIKLITKQLMLPLNKKGHKWALILTSLMLLL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 410066324  81 ISLNMLGLLPYTFTPTTQLSLNLGLAVPLWLATVIIGMRNQPTIALGHLLPEGTPTPLIPVLIIIETISLFIRPIALGVR 160
Cdd:MTH00120  81 LLINLLGLLPYTFTPTTQLSMNMALAIPLWLATVLTGLRNQPTTSLAHLLPEGTPTPLIPALILIETISLLIRPLALGVR 160

                        170       180       190
                 ....*....|....*....|....*....|...
gi 410066324 161 LTANLTAGHLLIQLIATAAFVLLPLMPTVAILT 193
Cdd:MTH00120 161 LTANLTAGHLLIQLISTATLNLLPTMPTLSLLT 193
ATP6 MTH00179
ATP synthase F0 subunit 6; Provisional
 1-193 5.70e-80

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177230  Cd Length: 227  Bit Score: 237.54  E-value: 5.70e-80
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 410066324   1 MTLSFFDQFMSPSLLGIPLMALALTLPWTLFPTPTPRWLHSRMLALQSWFINRFAQELLLPLSPAGHKWAMLFTSLMLYL 80
Cdd:MTH00179   1 MMLSMFDQFESPSLLGIPLLALALLLPWLLFPSLTNRWLNNRLSTLQSWFFGSFTFQLMQPINKKGHKWAVLFLSLMLFL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 410066324  81 ISLNMLGLLPYTFTPTTQLSLNLGLAVPLWLATVIIGMRNQPTIALGHLLPEGTPTPLIPVLIIIETISLFIRPIALGVR 160
Cdd:MTH00179  81 LTLNLLGLLPYTFTPTTQLSLNLGLALPLWLGTVLYGLFNQPTIALAHLLPEGTPTPLIPMLVWIETISLLIRPLALGVR 160

                        170       180       190
                 ....*....|....*....|....*....|...
gi 410066324 161 LTANLTAGHLLIQLIATAAFVLLPLMPTVAILT 193
Cdd:MTH00179 161 LTANITAGHLLMHLISSAVFVLMNFMGMVALLT 193
ATP6 MTH00101
ATP synthase F0 subunit 6; Validated
 1-193 4.84e-61

ATP synthase F0 subunit 6; Validated


Pssm-ID: 177163  Cd Length: 226  Bit Score: 189.39  E-value: 4.84e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 410066324   1 MTLSFFDQFMSPSLLGIPLMALALTLPWTLFPTPTpRWLHSRMLALQSWFINRFAQELLLPLSPAGHKWAMLFTSLMLYL 80
Cdd:MTH00101   1 MNENLFASFITPTILGLPIVTLIIMFPSLLFPTPN-RLINNRLISIQQWLIQLTSKQMMTIHNTKGQTWSLMLMSLILFI 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 410066324  81 ISLNMLGLLPYTFTPTTQLSLNLGLAVPLWLATVIIGMRNQPTIALGHLLPEGTPTPLIPVLIIIETISLFIRPIALGVR 160
Cdd:MTH00101  80 GSTNLLGLLPHSFTPTTQLSMNLGMAIPLWAGTVITGFRNKTKASLAHFLPQGTPTPLIPMLVIIETISLFIQPMALAVR 159

                        170       180       190
                 ....*....|....*....|....*....|...
gi 410066324 161 LTANLTAGHLLIQLIATAAFVLLPLMPTVAILT 193
Cdd:MTH00101 160 LTANITAGHLLIHLIGGATLALMSISTTTALIT 192
ATP6 MTH00035
ATP synthase F0 subunit 6; Validated
 4-182 2.75e-40

ATP synthase F0 subunit 6; Validated


Pssm-ID: 177110  Cd Length: 229  Bit Score: 136.64  E-value: 2.75e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 410066324   4 SFFDQFMSPSLLGIPL--MALALTLPWTLFPTPTpRWLHSRMLALQSWFINRFAQELLLPLSPAGHKWAMLFTSLMLYLI 81
Cdd:MTH00035   6 SIFGQFSPDTILFIPLtlLSSVIALSWLFFINPT-NWLPSRSQSIWLTFRQEILKLIFQNTNPNTAPWAGLLTTVFILIL 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 410066324  82 SLNMLGLLPYTFTPTTQLSLNLGLAVPLWLATVIIGMRNQPTIALGHLLPEGTPTPLIPVLIIIETISLFIRPIALGVRL 161
Cdd:MTH00035  85 SINVLGLFPYAFTSTSHISLTYSLGIPLWMSVNILGFYLAFNSRLSHLVPQGTPSFLIPLMVWIETLSLFAQPIALGLRL 164

                        170       180
                 ....*....|....*....|.
gi 410066324 162 TANLTAGHLLIQLIATAAFVL 182
Cdd:MTH00035 165 AANLTAGHLLIFLLSTAIWEL 185
ATP_synt_6_or_A TIGR01131
ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Bacterial forms should be ...
 4-193 9.76e-40

ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Bacterial forms should be designated ATP synthase, F0 subunit A; eukaryotic (chloroplast and mitochondrial) forms should be designated ATP synthase, F0 subunit 6. The F1/F0 ATP synthase is a multisubunit, membrane associated enzyme found in bacteria and mitochondria and chloroplast. This enzyme is principally involved in the synthesis of ATP from ADP and inorganic phosphate by coupling the energy derived from the proton electrochemical gradient across the biological membrane. A brief description of this multisubunit enzyme complex: F1 and F0 represent two major clusters of subunits. Individual subunits in each of these clusters are named differently in prokaryotes and in organelles e.g., mitochondria and chloroplast. The bacterial equivalent of subunit 6 is named subunit 'A'. It has been shown that proton is conducted though this subunit. Typically, deprotonation and reprotonation of the acidic amino acid side-chains are implicated in the process. [Energy metabolism, ATP-proton motive force interconversion]


Pssm-ID: 273458  Cd Length: 226  Bit Score: 135.03  E-value: 9.76e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 410066324    4 SFFDQFMSPSLLGIPLMALALTLPWTLFPTPTPRWL-HSRMLALQSWFINRFAQELLLPLSPAGHKWAMLFTSLMLYLIS 82
Cdd:TIGR01131   4 QFDISPITLFSLTLLSLILLLSLLIFLISSSLSRWLiPSRWQNLMESIYEFVLSIVKSQIGGKKGKFFPLIFTLFLFILI 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 410066324   83 LNMLGLLPYTFTPTTQLSLNLGLAVPLWLATVIIGMRNQPTIALGHLLPEGTPTPLIPVLIIIETISLFIRPIALGVRLT 162
Cdd:TIGR01131  84 SNLLGLIPYSFTPTSHLSFTLGLALPLWLGLTISGFRKHPKGFLAHLVPSGTPLPLIPFLVIIETISYLARPISLSVRLF 163

                         170       180       190
                  ....*....|....*....|....*....|.
gi 410066324  163 ANLTAGHLLIQLIATAAFVLLPLMPTVAILT 193
Cdd:TIGR01131 164 ANISAGHLLLTLLSGLLFSLMSSAIFALLLL 194
ATP6 MTH00157
ATP synthase F0 subunit 6; Provisional
 41-193 5.79e-34

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 214441  Cd Length: 223  Bit Score: 119.89  E-value: 5.79e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 410066324  41 SRMLALQSWFINRFAQELLLPLSPAGHKWAMLFTSLMLYLISLNMLGLLPYTFTPTTQLSLNLGLAVPLWLATVIIGMRN 120
Cdd:MTH00157  40 SRYNILWNKILKTLHKEFKTLLGPKNKGSTLIFISLFSFILFNNFLGLFPYIFTSTSHLSLTLSLALPLWLSFMLFGWIN 119

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 410066324 121 QPTIALGHLLPEGTPTPLIPVLIIIETISLFIRPIALGVRLTANLTAGHLLIQLIATAAFVLLPLMPTVAILT 193
Cdd:MTH00157 120 NTNHMFAHLVPQGTPPILMPFMVLIETISNLIRPGTLAVRLAANMIAGHLLLTLLGNTGPSLSSMILSILILI 192
ATP6 MTH00176
ATP synthase F0 subunit 6; Provisional
 1-193 9.13e-32

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 214449  Cd Length: 229  Bit Score: 114.36  E-value: 9.13e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 410066324   1 MTLSFFDQFMSPSLLGIPLMALALTLPWT-LFPTPTPRWL-HSRMLALQSWFINRFAQELLLPLSPAGHKWAMLFTSLML 78
Cdd:MTH00176   1 MLVDLFSSFDPPNKNIFSMISLSWITLLLfLLLMPSSVWFcPSKLQVFMLMFSTFLPEMILRSNGSYILGSASIIISLFI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 410066324  79 YLISLNMLGLLPYTFTPTTQLSLNLGLAVPLWLATVIIGMRNQPTIALGHLLPEGTPTPLIPVLIIIETISLFIRPIALG 158
Cdd:MTH00176  81 LVMSLNLSGLIPYVFTSTSHLVITLSLALPLWLGVILSGFINNFYSRLSHLVPQGTPPLLNPFLVLIELVSLLIRPLTLA 160

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 410066324 159 VRLTANLTAGHLLIQLIATAAFVLLPLMPTVAILT 193
Cdd:MTH00176 161 VRLAANLSAGHLLLGLLGAAMWGLLPVSPLIGFLL 195
ATP-synt_Fo_a_6 cd00310
ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms ...
 66-192 3.16e-31

ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms are designated as ATP synthase, Fo complex, subunit a; eukaryotic (chloroplast and mitochondrial) forms are designated as ATP synthase, Fo complex, subunit 6. The F-ATP synthases (also called FoF1-ATPases) consist of two structural domains: F1 (factor one) complex containing the soluble catalytic core, and Fo (oligomycin sensitive factor) complex containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. F-ATP synthases are primarily found in the inner membranes of eukaryotic mitochondria, in the thylakoid membranes of chloroplasts or in the plasma membranes of bacteria. F-ATP synthase has also been found in the archaea Methanosarcina acetivorans. F-ATP synthases are the primary producers of ATP, using the proton gradient generated by oxidative phosphorylation (mitochondria) or photosynthesis (chloroplasts). Alternatively, under conditions of low driving force, ATP synthases function as ATPases, thus generating a transmembrane proton or Na(+) gradient at the expense of energy derived from ATP hydrolysis.


Pssm-ID: 349411 [Multi-domain]  Cd Length: 156  Bit Score: 110.95  E-value: 3.16e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 410066324  66 GHKWAMLFTSLMLYLISLNMLGLLPYTFTPTTQLSLNLGLAVPLWLATVIIGMRNQPTIALGHLLPEGTPTPLIPVLIII 145
Cdd:cd00310    1 GKKYLPLLGTLFLFILFSNLLGLIPYSFTPTSHLNVTLALALIVFLGVHILGIKKHGLGFFLHFLPPGTPLPLAPLMVPI 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 410066324 146 ETISLFIRPIALGVRLTANLTAGHLLIQLIATAAFVLLPLMPTVAIL 192
Cdd:cd00310   81 ELISELIRPLSLSVRLFANMFAGHLLLALLSGLVPSLLSSVGLLPLL 127
ATP6 MTH00173
ATP synthase F0 subunit 6; Provisional
 4-176 3.53e-29

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 214448  Cd Length: 231  Bit Score: 107.64  E-value: 3.53e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 410066324   4 SFFDQFMSPSLLGIPLMALALTLPWTLFPTPTpRWLHSRMLALQSWFINRFAQELLLPLSPAGHKWAMLFTSLMLYLISL 83
Cdd:MTH00173   7 SSFDDHNSSFSSLSFLMWLLSLMSLFFFSSSV-WVSSSNLSSVFKLFVLTVSSQVTRSSGLNLGGFSLLLSSLFLFLISL 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 410066324  84 NMLGLLPYTFTPTTQLSLNLGLAVPLWLATVIIGMRNQPTIALGHLLPEGTPTPLIPVLIIIETISLFIRPIALGVRLTA 163
Cdd:MTH00173  86 NLSGLLPFVFSVTSHLAFTFSLALPLWLSLILSGLFYNPSKSLAGLVPAGAPAGLNPFLVLIETVSILIRPLTLTVRLLA 165

                        170
                 ....*....|...
gi 410066324 164 NLTAGHLLIQLIA 176
Cdd:MTH00173 166 NISAGHIVLTLIG 178
ATP6 MTH00172
ATP synthase F0 subunit 6; Provisional
 1-183 2.39e-25

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 214447  Cd Length: 232  Bit Score: 97.80  E-value: 2.39e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 410066324   1 MTLSFFDQFMSPSLLGI--PLMALALTLPWTLFPTPTPRWLHSRMLALQSWFINRFAQELLLPLSPAGHKWAMLFTSLML 78
Cdd:MTH00172   1 MSSSYFDQFNIVWLIGLtnSSIMMILVIIVVLLLFKGIKLIPKRWQSIIEIIYNHFHGVVKDNLGNEGLKYFPFIISLFF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 410066324  79 YLISLNMLGLLPYTFTPTTQLSLNLGLAVPLWLATVIIGMRNQPTIALGHLLPEGTPTPLIPVLIIIETISLFIRPIALG 158
Cdd:MTH00172  81 FIVFLNLLGLFPYVFTPTTHIVVTLGLSFSIIIGVTLAGFWRFKWDFFSILMPSGAPLGLAPLLVLIETVSYISRAISLG 160

                        170       180
                 ....*....|....*....|....*
gi 410066324 159 VRLTANLTAGHLLIQLIATAAFVLL 183
Cdd:MTH00172 161 VRLAANLSAGHLLFAILAGFGFNML 185
ATP-synt_A pfam00119
ATP synthase A chain;
66-193 2.90e-25

ATP synthase A chain;


Pssm-ID: 459679 [Multi-domain]  Cd Length: 216  Bit Score: 97.18  E-value: 2.90e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 410066324   66 GHKWAMLFTSLMLYLISLNMLGLL---PYTFTPTTQLSLNLGLAVPLWLATVIIGMRNQPTIA-LGHLLPEGTPTPLIPV 141
Cdd:pfam00119  54 GRKFFPLLLTLFFFILVSNLLGLIpksPGGFTVTADINVTLALALIVFLLVHYYGIKKHGLGGyFKKLFVPPVPLPLVPL 133

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 410066324  142 LIIIETISLFIRPIALGVRLTANLTAGHLLIQLIATAAFVLLPLMPTVAILT 193
Cdd:pfam00119 134 LLPIEIISEFARPVSLSLRLFGNMLAGHLLLLLLAGLIFALLSAGFLLGVIP 185
ATP6 MTH00005
ATP synthase F0 subunit 6; Provisional
 72-179 1.03e-22

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 164583  Cd Length: 231  Bit Score: 90.95  E-value: 1.03e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 410066324  72 LFTSLMLYLISLNMLGLLPYTFTPTTQLSLNLGLAVPLWLATVIIGMRNQPTIALGHLLPEGTPTPLIPVLIIIETISLF 151
Cdd:MTH00005  76 LISALFTMIILMNLSGLLPYVFSTSSHLIFTLTLGLPLWLSLIMSSVTFSPKKFAAHLLPGGAPDWLNPFLVLIETISIL 155

                         90       100
                 ....*....|....*....|....*...
gi 410066324 152 IRPIALGVRLTANLTAGHLLIQLIATAA 179
Cdd:MTH00005 156 VRPITLSFRLAANMSAGHIVLSLIGIYA 183
ATP6 MTH00175
ATP synthase F0 subunit 6; Provisional
 1-183 1.18e-19

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177228  Cd Length: 244  Bit Score: 83.13  E-value: 1.18e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 410066324   1 MTLSFFDQFMSPSLLGIP---------------LMALALTLPWTLFPTP--TPRWLHSRMLALQSwFINRFAQElllPLS 63
Cdd:MTH00175   1 MLAAYFDQFNIIRLITIQaflgdwlvtftnssmMMVLAVIIFWLLLKGDklIPNRWQSIMELIYL-NIRSVVHD---NLG 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 410066324  64 PAGHKWAMLFTSLMLYLISLNMLGLLPYTFTPTTQLSLNLGLAVPLWLATVIIGMRNQPTIALGHLLPEGTPTPLIPVLI 143
Cdd:MTH00175  77 KSGQKYFPFILSLFLFIAILNILGLFPYVFTPTAHIIITFGLSLSIIIAVTLLGFLTFKWNFLSILMPGGAPLVLAPFLV 156

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 410066324 144 IIETISLFIRPIALGVRLTANLTAGHLLIQLIATAAFVLL 183
Cdd:MTH00175 157 LIETLSYLIRAISLGVRLAANISAGHLLFAILSGFAFNML 196
AtpB COG0356
FoF1-type ATP synthase, membrane subunit a [Energy production and conversion]; FoF1-type ATP ...
 61-191 7.86e-19

FoF1-type ATP synthase, membrane subunit a [Energy production and conversion]; FoF1-type ATP synthase, membrane subunit a is part of the Pathway/BioSystem: FoF1-type ATP synthase


Pssm-ID: 440125 [Multi-domain]  Cd Length: 212  Bit Score: 80.12  E-value: 7.86e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 410066324  61 PLSPAGHKWAMLFTSLMLYLISLNMLGLLPYTFTPTTQLSLNLGLAVPLWLATVIIGMRNQPTIA-LGHLLPEGTPtPLI 139
Cdd:COG0356   49 TIGKKGRKFAPLLLTLFLFILVSNLLGLIPGLFPPTADINVTLALALIVFVLVHYYGIKKKGLGGyLKHLFFPPFP-WLA 127

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 410066324 140 PVLIIIETISLFIRPIALGVRLTANLTAGHLLIQLIATAAFVLLPLMPTVAI 191
Cdd:COG0356  128 PLMLPIEIISELARPLSLSLRLFGNMFAGHIILLLLAGLAPFLLLGVLSLLL 179
PRK05815 PRK05815
F0F1 ATP synthase subunit A; Validated
 66-193 8.31e-17

F0F1 ATP synthase subunit A; Validated


Pssm-ID: 235617  Cd Length: 227  Bit Score: 75.22  E-value: 8.31e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 410066324  66 GHKWAMLFTSLMLYLISLNMLGLLP-YTFTPTTQLSLNLGLAVPLWLATVIIGMRNQptiALGHLLPEGTPTPlIPVLII 144
Cdd:PRK05815  69 GKKFAPLAFTLFLFILLMNLLGLIPyLLFPPTADINVTLALALIVFVLVIYYGIKKK---GLGGYLKEFYLQP-HPLLLP 144

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 410066324 145 IETISLFIRPIALGVRLTANLTAGHLLIQLIATAAFVLLPLMPTVAILT 193
Cdd:PRK05815 145 IEIISEFSRPISLSLRLFGNMLAGELILALIALLGGAGLLLALAPLILP 193
ATP6 MTH00174
ATP synthase F0 subunit 6; Provisional
 62-183 7.47e-14

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 133799  Cd Length: 252  Bit Score: 67.66  E-value: 7.47e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 410066324  62 LSPAGHKWAMLFTSLMLYLISLNMLGLLPYTFTPTTQLSLNLGLAVPLWLATVIIGMRNQPTIALGHLLPEGTPTPLIPV 141
Cdd:MTH00174  83 LGNKGGNYLAFVLSLFILILFGNGLGLFPYVFTPTVHMVITLGLSFAIIVGTTLAGLITFRFNFFSILMPQGAPLALAPL 162

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 410066324 142 LIIIETISLFIRPIALGVRLTANLTAGHLLIQLIATAAFVLL 183
Cdd:MTH00174 163 LTIIETLSYISRAISLGVRLAANISSGHLLFSIIASFAWKMI 204
PRK13419 PRK13419
F0F1 ATP synthase subunit A; Provisional
 72-182 3.89e-11

F0F1 ATP synthase subunit A; Provisional


Pssm-ID: 237381  Cd Length: 342  Bit Score: 60.53  E-value: 3.89e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 410066324  72 LFTSLMLYLIsLNMLGLLPYTFTPTTQLSLNLGLAVPLWLATVIIGMRNQPTIALGHLLPEGTPTPLIPVLIIIETISLF 151
Cdd:PRK13419 174 LLTVFFFILV-CNLLGLVPYGATATGNINVTLTLAVFTFFITQYAAIKAHGIKGYLAHLTGGTHWSLWIIMIPIEFIGLF 252

                         90       100       110
                 ....*....|....*....|....*....|.
gi 410066324 152 IRPIALGVRLTANLTAGHLLIQLIATAAFVL 182
Cdd:PRK13419 253 TKPFALTVRLFANMTAGHIVILSLIFISFIL 283
ATP6 MTH00087
ATP synthase F0 subunit 6; Provisional
 71-175 2.63e-09

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177152  Cd Length: 195  Bit Score: 54.21  E-value: 2.63e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 410066324  71 MLFTSLMLYLISLNMLGLLPYTFTPTTQLSLNLGLAVPLWLATVIIGMRNQptIALGHLLPEGTPTPLIP-VLIIIETIS 149
Cdd:MTH00087  53 VISFFTFIVLLLFCFGGLFPYSFSPCGMVEFTFLYALVAWLSTFLSFLSKS--EKFSVYLSKGSDSFLKTfSMLFVEIVS 130

                         90       100
                 ....*....|....*....|....*.
gi 410066324 150 LFIRPIALGVRLTANLTAGHLLIQLI 175
Cdd:MTH00087 131 ELSRPLALTLRLTVNLMVGHLISSLL 156
PRK13417 PRK13417
F0F1 ATP synthase subunit A; Provisional
 94-172 1.20e-04

F0F1 ATP synthase subunit A; Provisional


Pssm-ID: 237380  Cd Length: 352  Bit Score: 41.80  E-value: 1.20e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 410066324  94 TPTTQLSLNLGLAVPLWLATVIIGMRNQPTIALGHLLPEGTPTPLIPVLIIIETI-SLFIRPIALGVRLTANLTAGHLLI 172
Cdd:PRK13417 217 TVTGDISVTMTLALLTMFLIYGAGFSYQGPKFIWHSVPNGVPLLLYPIMWPLEFIvSPMAKTFALTVRLLANMTAGHVII 296
ATP6 MTH00050
ATP synthase F0 subunit 6; Validated
 71-168 1.38e-03

ATP synthase F0 subunit 6; Validated


Pssm-ID: 177125  Cd Length: 170  Bit Score: 37.94  E-value: 1.38e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 410066324  71 MLFTSLMLYLISLNMLGLLPYTFTPTTQLSLNLGLAVPLWLATVIIGMRNQPTIALGHLLPEGTPTPLIPVLIIIETISL 150
Cdd:MTH00050  24 YYYSVVLFIVLFLFLLYRLPYIYSPFLFVVFLFVVVFPLFISLFLSRVFDSLNEFFSSFVPVGTPLYICPFVCIAETISY 103

                         90
                 ....*....|....*...
gi 410066324 151 FIRPIALGVRLTANLTAG 168
Cdd:MTH00050 104 IIRPVVLILRPFINISLG 121
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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