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Conserved domains on  [gi|559158796|gb|AHB01278|]
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spermidine/putrescine ABC transporter ATPase subunit [Brucella ceti TE10759-12]

Protein Classification

ABC transporter ATP-binding protein( domain architecture ID 11467437)

ABC transporter ATP-binding protein is the ATPase catalytic subunit of an ATP transporter complex responsible for coupling the energy of ATP hydrolysis to the import of one or more from a variety of substrates including Fe(3+) ions and polyamines such as spermidine and putrescine

CATH:  3.40.50.300
EC:  7.-.-.-
Gene Ontology:  GO:0042626|GO:0140359|GO:0005524|GO:0016887
PubMed:  25750732|24638992
SCOP:  4003976
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PotA COG3842
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...
 1-353 0e+00

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];


:

Pssm-ID: 443052 [Multi-domain]  Cd Length: 353  Bit Score: 535.45  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   1 MAFLNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQRNIGMV 80
Cdd:COG3842    3 MPALELENVSKRYGDVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDVTGLPPEKRNVGMV 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  81 FQAYALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEP 160
Cdd:COG3842   83 FQDYALFPHLTVAENVAFGLRMRGVPKAEIRARVAELLELVGLEGLADRYPHQLSGGQQQRVALARALAPEPRVLLLDEP 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 161 LSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNRPASRFVASFVGTLNML 240
Cdd:COG3842  163 LSALDAKLREEMREELRRLQRELGITFIYVTHDQEEALALADRIAVMNDGRIEQVGTPEEIYERPATRFVADFIGEANLL 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 241 EASVSEPAQNSIDLDGRQITVQeTLAHHPKGKPLTLALRPEAVSLeARKSHDTSLEATIDDVHFLGSVIRTRVILGKN-R 319
Cdd:COG3842  243 PGTVLGDEGGGVRTGGRTLEVP-ADAGLAAGGPVTVAIRPEDIRL-SPEGPENGLPGTVEDVVFLGSHVRYRVRLGDGqE 320

                        330       340       350
                 ....*....|....*....|....*....|....
gi 559158796 320 LSFDTFNDpTHPPPQRGDKVTVHFASHDLLVLAD 353
Cdd:COG3842  321 LVVRVPNR-AALPLEPGDRVGLSWDPEDVVVLPA 353
 
Name Accession Description Interval E-value
PotA COG3842
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...
 1-353 0e+00

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443052 [Multi-domain]  Cd Length: 353  Bit Score: 535.45  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   1 MAFLNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQRNIGMV 80
Cdd:COG3842    3 MPALELENVSKRYGDVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDVTGLPPEKRNVGMV 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  81 FQAYALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEP 160
Cdd:COG3842   83 FQDYALFPHLTVAENVAFGLRMRGVPKAEIRARVAELLELVGLEGLADRYPHQLSGGQQQRVALARALAPEPRVLLLDEP 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 161 LSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNRPASRFVASFVGTLNML 240
Cdd:COG3842  163 LSALDAKLREEMREELRRLQRELGITFIYVTHDQEEALALADRIAVMNDGRIEQVGTPEEIYERPATRFVADFIGEANLL 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 241 EASVSEPAQNSIDLDGRQITVQeTLAHHPKGKPLTLALRPEAVSLeARKSHDTSLEATIDDVHFLGSVIRTRVILGKN-R 319
Cdd:COG3842  243 PGTVLGDEGGGVRTGGRTLEVP-ADAGLAAGGPVTVAIRPEDIRL-SPEGPENGLPGTVEDVVFLGSHVRYRVRLGDGqE 320

                        330       340       350
                 ....*....|....*....|....*....|....
gi 559158796 320 LSFDTFNDpTHPPPQRGDKVTVHFASHDLLVLAD 353
Cdd:COG3842  321 LVVRVPNR-AALPLEPGDRVGLSWDPEDVVVLPA 353
PhnT2 TIGR03265
putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ...
 1-313 4.55e-147

putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ATP-binding protein is found in a number of genomes in operon-like contexts strongly suggesting a substrate specificity for 2-aminoethylphosphonate (2-AEP). The characterized PhnSTUV system is absent in the genomes in which this system is found. These genomes encode systems for the catabolism of 2-AEP, making the need for a 2-AEP-specific transporter likely. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274496 [Multi-domain]  Cd Length: 353  Bit Score: 419.06  E-value: 4.55e-147
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796    1 MAFLNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQRNIGMV 80
Cdd:TIGR03265   2 SPYLSIDNIRKRFGAFTALKDISLSVKKGEFVCLLGPSGCGKTTLLRIIAGLERQTAGTIYQGGRDITRLPPQKRDYGIV 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   81 FQAYALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEP 160
Cdd:TIGR03265  82 FQSYALFPNLTVADNIAYGLKNRGMGRAEVAERVAELLDLVGLPGSERKYPGQLSGGQQQRVALARALATSPGLLLLDEP 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  161 LSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNRPASRFVASFVGTLNML 240
Cdd:TIGR03265 162 LSALDARVREHLRTEIRQLQRRLGVTTIMVTHDQEEALSMADRIVVMNHGVIEQVGTPQEIYRHPATPFVADFVGEVNWL 241

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 559158796  241 EASVSEPAQNSIDldgrQITVQETLAHHPKGKPLTLALRPEAVSLEARKSHDTSLEATIDDVHFLGSVIRTRV 313
Cdd:TIGR03265 242 PGTRGGGSRARVG----GLTLACAPGLAQPGASVRLAVRPEDIRVSPAGNAANLLLARVEDMEFLGAFYRLRL 310
ABC_PotA_N cd03300
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ...
 4-235 2.42e-133

ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213267 [Multi-domain]  Cd Length: 232  Bit Score: 379.66  E-value: 2.42e-133
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQRNIGMVFQA 83
Cdd:cd03300    1 IELENVSKFYGGFVALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDGKDITNLPPHKRPVNTVFQN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  84 YALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSA 163
Cdd:cd03300   81 YALFPHLTVFENIAFGLRLKKLPKAEIKERVAEALDLVQLEGYANRKPSQLSGGQQQRVAIARALVNEPKVLLLDEPLGA 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 559158796 164 LDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNRPASRFVASFVG 235
Cdd:cd03300  161 LDLKLRKDMQLELKRLQKELGITFVFVTHDQEEALTMSDRIAVMNKGKIQQIGTPEEIYEEPANRFVADFIG 232
potA PRK09452
spermidine/putrescine ABC transporter ATP-binding protein PotA;
4-341 1.26e-132

spermidine/putrescine ABC transporter ATP-binding protein PotA;


Pssm-ID: 236523 [Multi-domain]  Cd Length: 375  Bit Score: 383.14  E-value: 1.26e-132
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQRNIGMVFQA 83
Cdd:PRK09452  15 VELRGISKSFDGKEVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIMLDGQDITHVPAENRHVNTVFQS 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  84 YALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSA 163
Cdd:PRK09452  95 YALFPHMTVFENVAFGLRMQKTPAAEITPRVMEALRMVQLEEFAQRKPHQLSGGQQQRVAIARAVVNKPKVLLLDESLSA 174

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 164 LDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNRPASRFVASFVGTLNMLEAS 243
Cdd:PRK09452 175 LDYKLRKQMQNELKALQRKLGITFVFVTHDQEEALTMSDRIVVMRDGRIEQDGTPREIYEEPKNLFVARFIGEINIFDAT 254

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 244 VSEPAQNS---IDLDGRQITVQETLAHHPkGKPLTLALRPEAVSLEARkSHDTSLEAT---IDDVHFLGSVIRTRVIL-- 315
Cdd:PRK09452 255 VIERLDEQrvrANVEGRECNIYVNFAVEP-GQKLHVLLRPEDLRVEEI-NDDEHAEGLigyVRERNYKGMTLDSVVELen 332

                        330       340       350
                 ....*....|....*....|....*....|
gi 559158796 316 GKNRLSFDTFN--DPT--HPPpqrGDKVTV 341
Cdd:PRK09452 333 GKMVMVSEFFNedDPDfdHSL---GQKVAV 359
tungstate_WtpC NF040840
tungstate ABC transporter ATP-binding protein WtpC;
19-316 1.40e-98

tungstate ABC transporter ATP-binding protein WtpC;


Pssm-ID: 468779 [Multi-domain]  Cd Length: 347  Bit Score: 295.45  E-value: 1.40e-98
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  19 VHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQRNIGMVFQAYALFPNMTVAQNVSF 98
Cdd:NF040840  16 LRDISLEVKEGEYFIILGPSGAGKTVLLELIAGIWPPDSGKIYLDGKDITNLPPEKRGIAYVYQNYMLFPHKTVFENIAF 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  99 GLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSALDAKIRISLREEIRA 178
Cdd:NF040840  96 GLKLRKVPKEEIERKVKEIMELLGISHLLHRKPRTLSGGEQQRVALARALIIEPKLLLLDEPLSALDVQTRDELIREMKR 175

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 179 IQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNRPASRFVASFVGTLNMLEASVSEPAQ-NSIDLDGR 257
Cdd:NF040840 176 WHREFGFTAIHVTHNFEEALSLADRVGIMLNGRLSQVGDVREVFRRPKNEFVARFVGFENIIEGVAEKGGEgTILDTGNI 255

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 559158796 258 QItvqeTLAHHPKGKpLTLALRPEAVSLEARK---SHDTSLEATIDDVHFLGSVIRTRVILG 316
Cdd:NF040840 256 KI----ELPEEKKGK-VRIGIRPEDITISTEKvktSARNEFKGKVEEIEDLGPLVKLTLDVG 312
ABC_ATP_DarD NF038007
darobactin export ABC transporter ATP-binding protein;
4-211 3.19e-58

darobactin export ABC transporter ATP-binding protein;


Pssm-ID: 411600 [Multi-domain]  Cd Length: 218  Bit Score: 187.62  E-value: 3.19e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNT----VVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQRN--- 76
Cdd:NF038007   2 LNMQNAEKCYITKTiktkVLNHLNFSVEKGDFVSIMGPSGSGKSTLLNIIGMFDSLDSGSLTLAGKEVTNLSYSQKIilr 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  77 ---IGMVFQAYALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQ 153
Cdd:NF038007  82 relIGYIFQSFNLIPHLSIFDNVALPLKYRGVAKKERIERVNQVLNLFGIDNRRNHKPMQLSGGQQQRVAIARAMVSNPA 161

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 559158796 154 VLLLDEPLSALDAKIRISLREEIRAIQQKlGITTVFVTHdQEEALSISDRIVVMHEGR 211
Cdd:NF038007 162 LLLADEPTGNLDSKNARAVLQQLKYINQK-GTTIIMVTH-SDEASTYGNRIINMKDGK 217
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
 19-162 6.82e-52

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 168.98  E-value: 6.82e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   19 VHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVV--NLRPNQRNIGMVFQAYALFPNMTVAQNV 96
Cdd:pfam00005   1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTddERKSLRKEIGYVFQDPQLFPRLTVRENL 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   97 SFGLRVSGKSRSEIDATVKEMLSLIRLDHLADR----YPYQMSGGQQQRVALARALATKPQVLLLDEPLS 162
Cdd:pfam00005  81 RLGLLLKGLSKREKDARAEEALEKLGLGDLADRpvgeRPGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
12-207 1.86e-28

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 109.25  E-value: 1.86e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  12 SFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQRNIGmvfqayALFPnMT 91
Cdd:NF040873   1 GYGGRPVLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTVRRAGGARVAYVPQRSEVP------DSLP-LT 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  92 VAQNVSFGL----RVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSALDAK 167
Cdd:NF040873  74 VRDLVAMGRwarrGLWRRLTRDDRAAVDDALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLLLDEPTTGLDAE 153

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 559158796 168 IRISLREEIRAIQQKlGITTVFVTHDQEEALSIsDRIVVM 207
Cdd:NF040873 154 SRERIIALLAEEHAR-GATVVVVTHDLELVRRA-DPCVLL 191
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
7-211 5.37e-23

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 100.20  E-value: 5.37e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   7 KNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSI-----EIDGKDvVNLRpnqRNIGMVF 81
Cdd:NF033858 270 RGLTMRFGDFTAVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAwlfgqPVDAGD-IATR---RRVGYMS 345

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  82 QAYALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPL 161
Cdd:NF033858 346 QAFSLYGELTVRQNLELHARLFHLPAAEIAARVAEMLERFDLADVADALPDSLPLGIRQRLSLAVAVIHKPELLILDEPT 425

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 559158796 162 SALDAKIR-------ISL-REEiraiqqklGItTVFV-THDQEEALSiSDRIVVMHEGR 211
Cdd:NF033858 426 SGVDPVARdmfwrllIELsRED--------GV-TIFIsTHFMNEAER-CDRISLMHAGR 474
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
4-215 1.23e-12

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 68.22  E-value: 1.23e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVlRMIAGFETPDNGSIEIDGKD-VVNLRPNQRNIGMVFQ 82
Cdd:NF000106  14 VEVRGLVKHFGEVKAVDGVDLDVREGTVLGVLGP*GAA**RG-ALPAHV*GPDAGRRPWRF*TwCANRRALRRTIG*HRP 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  83 A-YALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPL 161
Cdd:NF000106  93 Vr*GRRESFSGRENLYMIGR*LDLSRKDARARADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPT 172

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 162 SALDAKIRISLREEIRAIQQKlGITTVFVTHDQEEA------LSISDRIVVMHEGRADQI 215
Cdd:NF000106 173 TGLDPRTRNEVWDEVRSMVRD-GATVLLTTQYMEEAeqlaheLTVIDRGRVIADGKVDEL 231
GguA NF040905
sugar ABC transporter ATP-binding protein;
4-211 5.09e-12

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 66.74  E-value: 5.09e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAG------FEtpdnGSIEIDGKdVVNLR----PN 73
Cdd:NF040905   2 LEMRGITKTFPGVKALDDVNLSVREGEIHALCGENGAGKSTLMKVLSGvyphgsYE----GEILFDGE-VCRFKdirdSE 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  74 QRNIGMVFQAYALFPNMTVAQNVSFGLRVSGK---SRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALAT 150
Cdd:NF040905  77 ALGIVIIHQELALIPYLSIAENIFLGNERAKRgviDWNETNRRARELLAKVGLDESPDTLVTDIGVGKQQLVEIAKALSK 156

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 559158796 151 KPQVLLLDEPLSALDAKIRISLREEIRAIQQKlGITTVFVTHDQEEALSISDRIVVMHEGR 211
Cdd:NF040905 157 DVKLLILDEPTAALNEEDSAALLDLLLELKAQ-GITSIIISHKLNEIRRVADSITVLRDGR 216
GguA NF040905
sugar ABC transporter ATP-binding protein;
18-211 5.52e-12

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 66.74  E-value: 5.52e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  18 VVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAG--FETPDNGSIEIDGKDVvNLRPNQRNI--GMVF-----QAYALFP 88
Cdd:NF040905 275 VVDDVSLNVRRGEIVGIAGLMGAGRTELAMSVFGrsYGRNISGTVFKDGKEV-DVSTVSDAIdaGLAYvtedrKGYGLNL 353

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  89 NMTVAQNVSF-GL-RVSgkSRSEIDAtVKEMLSlirldhlADRYPYQM--------------SGGQQQRVALARALATKP 152
Cdd:NF040905 354 IDDIKRNITLaNLgKVS--RRGVIDE-NEEIKV-------AEEYRKKMniktpsvfqkvgnlSGGNQQKVVLSKWLFTDP 423

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 559158796 153 QVLLLDEPLSALD--AKIrislreEIRAIQQKL---GITTVFVTHDQEEALSISDRIVVMHEGR 211
Cdd:NF040905 424 DVLILDEPTRGIDvgAKY------EIYTIINELaaeGKGVIVISSELPELLGMCDRIYVMNEGR 481
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 28-207 7.60e-12

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 62.39  E-value: 7.60e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796    28 KGEFVSFLGPSGCGKTTVLRMIAGFETPDNGS-IEIDGkdvvnlrpnqrnigmvfqayalfpnmtvaqnvsfglrvsgks 106
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPGGGvIYIDG------------------------------------------ 38

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   107 rseidATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSALDAKIRISLREEIRA-----IQQ 181
Cdd:smart00382  39 -----EDILEEVLDQLLLIIVGGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLLLLEELrllllLKS 113

                          170       180       190
                   ....*....|....*....|....*....|.
gi 559158796   182 KLGITTVFVTHDQEEALS-----ISDRIVVM 207
Cdd:smart00382 114 EKNLTVILTTNDEKDLGPallrrRFDRRIVL 144
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
6-231 3.13e-11

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 64.76  E-value: 3.13e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   6 IKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQRNIGMVfqAYA 85
Cdd:NF033858   4 LEGVSHRYGKTVALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRVEVLGGDMADARHRRAVCPRI--AYM 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  86 -------LFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLD 158
Cdd:NF033858  82 pqglgknLYPTLSVFENLDFFGRLFGQDAAERRRRIDELLRATGLAPFADRPAGKLSGGMKQKLGLCCALIHDPDLLILD 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 159 EPLSALDAKIRI---SLREEIRAiqQKLGITTVFVTHDQEEALSIsDRIVVMHEGRADQIGSPFDIYNRPASR-----FV 230
Cdd:NF033858 162 EPTTGVDPLSRRqfwELIDRIRA--ERPGMSVLVATAYMEEAERF-DWLVAMDAGRVLATGTPAELLARTGADtleaaFI 238


                 .
gi 559158796 231 A 231
Cdd:NF033858 239 A 239
 
Name Accession Description Interval E-value
PotA COG3842
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...
 1-353 0e+00

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443052 [Multi-domain]  Cd Length: 353  Bit Score: 535.45  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   1 MAFLNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQRNIGMV 80
Cdd:COG3842    3 MPALELENVSKRYGDVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDVTGLPPEKRNVGMV 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  81 FQAYALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEP 160
Cdd:COG3842   83 FQDYALFPHLTVAENVAFGLRMRGVPKAEIRARVAELLELVGLEGLADRYPHQLSGGQQQRVALARALAPEPRVLLLDEP 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 161 LSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNRPASRFVASFVGTLNML 240
Cdd:COG3842  163 LSALDAKLREEMREELRRLQRELGITFIYVTHDQEEALALADRIAVMNDGRIEQVGTPEEIYERPATRFVADFIGEANLL 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 241 EASVSEPAQNSIDLDGRQITVQeTLAHHPKGKPLTLALRPEAVSLeARKSHDTSLEATIDDVHFLGSVIRTRVILGKN-R 319
Cdd:COG3842  243 PGTVLGDEGGGVRTGGRTLEVP-ADAGLAAGGPVTVAIRPEDIRL-SPEGPENGLPGTVEDVVFLGSHVRYRVRLGDGqE 320

                        330       340       350
                 ....*....|....*....|....*....|....
gi 559158796 320 LSFDTFNDpTHPPPQRGDKVTVHFASHDLLVLAD 353
Cdd:COG3842  321 LVVRVPNR-AALPLEPGDRVGLSWDPEDVVVLPA 353
MalK COG3839
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ...
 1-350 6.22e-167

ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];


Pssm-ID: 443050 [Multi-domain]  Cd Length: 352  Bit Score: 469.17  E-value: 6.22e-167
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   1 MAFLNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQRNIGMV 80
Cdd:COG3839    1 MASLELENVSKSYGGVEALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPTSGEILIGGRDVTDLPPKDRNIAMV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  81 FQAYALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEP 160
Cdd:COG3839   81 FQSYALYPHMTVYENIAFPLKLRKVPKAEIDRRVREAAELLGLEDLLDRKPKQLSGGQRQRVALGRALVREPKVFLLDEP 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 161 LSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNRPASRFVASFVGT--LN 238
Cdd:COG3839  161 LSNLDAKLRVEMRAEIKRLHRRLGTTTIYVTHDQVEAMTLADRIAVMNDGRIQQVGTPEELYDRPANLFVAGFIGSppMN 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 239 MLEASVSEpaqNSIDLDGRQITVQETLAHHPkGKPLTLALRPEAVSLEArkSHDTSLEATIDDVHFLGSVIRTRVILGKN 318
Cdd:COG3839  241 LLPGTVEG---GGVRLGGVRLPLPAALAAAA-GGEVTLGIRPEHLRLAD--EGDGGLEATVEVVEPLGSETLVHVRLGGQ 314

                        330       340       350
                 ....*....|....*....|....*....|..
gi 559158796 319 RLSFDTfndPTHPPPQRGDKVTVHFASHDLLV 350
Cdd:COG3839  315 ELVARV---PGDTRLRPGDTVRLAFDPERLHL 343
PhnT2 TIGR03265
putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ...
 1-313 4.55e-147

putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ATP-binding protein is found in a number of genomes in operon-like contexts strongly suggesting a substrate specificity for 2-aminoethylphosphonate (2-AEP). The characterized PhnSTUV system is absent in the genomes in which this system is found. These genomes encode systems for the catabolism of 2-AEP, making the need for a 2-AEP-specific transporter likely. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274496 [Multi-domain]  Cd Length: 353  Bit Score: 419.06  E-value: 4.55e-147
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796    1 MAFLNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQRNIGMV 80
Cdd:TIGR03265   2 SPYLSIDNIRKRFGAFTALKDISLSVKKGEFVCLLGPSGCGKTTLLRIIAGLERQTAGTIYQGGRDITRLPPQKRDYGIV 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   81 FQAYALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEP 160
Cdd:TIGR03265  82 FQSYALFPNLTVADNIAYGLKNRGMGRAEVAERVAELLDLVGLPGSERKYPGQLSGGQQQRVALARALATSPGLLLLDEP 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  161 LSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNRPASRFVASFVGTLNML 240
Cdd:TIGR03265 162 LSALDARVREHLRTEIRQLQRRLGVTTIMVTHDQEEALSMADRIVVMNHGVIEQVGTPQEIYRHPATPFVADFVGEVNWL 241

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 559158796  241 EASVSEPAQNSIDldgrQITVQETLAHHPKGKPLTLALRPEAVSLEARKSHDTSLEATIDDVHFLGSVIRTRV 313
Cdd:TIGR03265 242 PGTRGGGSRARVG----GLTLACAPGLAQPGASVRLAVRPEDIRVSPAGNAANLLLARVEDMEFLGAFYRLRL 310
CysA COG1118
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ...
 4-350 1.86e-145

ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440735 [Multi-domain]  Cd Length: 348  Bit Score: 414.54  E-value: 1.86e-145
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDV-VNLRPNQRNIGMVFQ 82
Cdd:COG1118    3 IEVRNISKRFGSFTLLDDVSLEIASGELVALLGPSGSGKTTLLRIIAGLETPDSGRIVLNGRDLfTNLPPRERRVGFVFQ 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  83 AYALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLS 162
Cdd:COG1118   83 HYALFPHMTVAENIAFGLRVRPPSKAEIRARVEELLELVQLEGLADRYPSQLSGGQRQRVALARALAVEPEVLLLDEPFG 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 163 ALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNRPASRFVASFVGTLNMLEA 242
Cdd:COG1118  163 ALDAKVRKELRRWLRRLHDELGGTTVFVTHDQEEALELADRVVVMNQGRIEQVGTPDEVYDRPATPFVARFLGCVNVLRG 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 243 SVSEPAqnsIDLDGRQITVQETLAHHPKgkplTLALRPEAVSLEARKSHDTSLEATIDDVHFLGSVIRTRVILGKN---- 318
Cdd:COG1118  243 RVIGGQ---LEADGLTLPVAEPLPDGPA----VAGVRPHDIEVSREPEGENTFPATVARVSELGPEVRVELKLEDGegqp 315

                        330       340       350
                 ....*....|....*....|....*....|....*
gi 559158796 319 ---RLSFDTFNDpthPPPQRGDKVTVHFASHDLLV 350
Cdd:COG1118  316 leaEVTKEAWAE---LGLAPGDPVYLRPRPARVFL 347
ABC_PotA_N cd03300
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ...
 4-235 2.42e-133

ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213267 [Multi-domain]  Cd Length: 232  Bit Score: 379.66  E-value: 2.42e-133
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQRNIGMVFQA 83
Cdd:cd03300    1 IELENVSKFYGGFVALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDGKDITNLPPHKRPVNTVFQN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  84 YALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSA 163
Cdd:cd03300   81 YALFPHLTVFENIAFGLRLKKLPKAEIKERVAEALDLVQLEGYANRKPSQLSGGQQQRVAIARALVNEPKVLLLDEPLGA 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 559158796 164 LDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNRPASRFVASFVG 235
Cdd:cd03300  161 LDLKLRKDMQLELKRLQKELGITFVFVTHDQEEALTMSDRIAVMNKGKIQQIGTPEEIYEEPANRFVADFIG 232
potA PRK09452
spermidine/putrescine ABC transporter ATP-binding protein PotA;
4-341 1.26e-132

spermidine/putrescine ABC transporter ATP-binding protein PotA;


Pssm-ID: 236523 [Multi-domain]  Cd Length: 375  Bit Score: 383.14  E-value: 1.26e-132
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQRNIGMVFQA 83
Cdd:PRK09452  15 VELRGISKSFDGKEVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIMLDGQDITHVPAENRHVNTVFQS 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  84 YALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSA 163
Cdd:PRK09452  95 YALFPHMTVFENVAFGLRMQKTPAAEITPRVMEALRMVQLEEFAQRKPHQLSGGQQQRVAIARAVVNKPKVLLLDESLSA 174

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 164 LDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNRPASRFVASFVGTLNMLEAS 243
Cdd:PRK09452 175 LDYKLRKQMQNELKALQRKLGITFVFVTHDQEEALTMSDRIVVMRDGRIEQDGTPREIYEEPKNLFVARFIGEINIFDAT 254

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 244 VSEPAQNS---IDLDGRQITVQETLAHHPkGKPLTLALRPEAVSLEARkSHDTSLEAT---IDDVHFLGSVIRTRVIL-- 315
Cdd:PRK09452 255 VIERLDEQrvrANVEGRECNIYVNFAVEP-GQKLHVLLRPEDLRVEEI-NDDEHAEGLigyVRERNYKGMTLDSVVELen 332

                        330       340       350
                 ....*....|....*....|....*....|
gi 559158796 316 GKNRLSFDTFN--DPT--HPPpqrGDKVTV 341
Cdd:PRK09452 333 GKMVMVSEFFNedDPDfdHSL---GQKVAV 359
fbpC PRK11432
ferric ABC transporter ATP-binding protein;
3-353 2.23e-125

ferric ABC transporter ATP-binding protein;


Pssm-ID: 183133 [Multi-domain]  Cd Length: 351  Bit Score: 364.04  E-value: 2.23e-125
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   3 FLNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQRNIGMVFQ 82
Cdd:PRK11432   6 FVVLKNITKRFGSNTVIDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQIFIDGEDVTHRSIQQRDICMVFQ 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  83 AYALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLS 162
Cdd:PRK11432  86 SYALFPHMSLGENVGYGLKMLGVPKEERKQRVKEALELVDLAGFEDRYVDQISGGQQQRVALARALILKPKVLLFDEPLS 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 163 ALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNRPASRFVASFVGTLNMLEA 242
Cdd:PRK11432 166 NLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDTVIVMNKGKIMQIGSPQELYRQPASRFMASFMGDANIFPA 245

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 243 SVSepaQNSIDLDGRQITVQETLAHHPKGKPLTLALRPEAVSLEARKShdTSLEATIDDVHFLGSVIRTRVILGKNRLSF 322
Cdd:PRK11432 246 TLS---GDYVDIYGYRLPRPAAFAFNLPDGECTVGVRPEAITLSEQGE--ESQRCTIKHVAYMGPQYEVTVDWHGQELLL 320

                        330       340       350
                 ....*....|....*....|....*....|.
gi 559158796 323 DTfnDPTHPPPQRGDKVTVHFASHDLLVLAD 353
Cdd:PRK11432 321 QV--NATQLQPDLGEHYYLEIHPYGMFLLAD 349
ugpC PRK11650
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
1-348 1.27e-121

sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;


Pssm-ID: 236947 [Multi-domain]  Cd Length: 356  Bit Score: 354.53  E-value: 1.27e-121
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   1 MAFLNIKNLKKSFGTNT-VVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQRNIGM 79
Cdd:PRK11650   1 MAGLKLQAVRKSYDGKTqVIKGIDLDVADGEFIVLVGPSGCGKSTLLRMVAGLERITSGEIWIGGRVVNELEPADRDIAM 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  80 VFQAYALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDE 159
Cdd:PRK11650  81 VFQNYALYPHMSVRENMAYGLKIRGMPKAEIEERVAEAARILELEPLLDRKPRELSGGQRQRVAMGRAIVREPAVFLFDE 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 160 PLSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNRPASRFVASFVGT--L 237
Cdd:PRK11650 161 PLSNLDAKLRVQMRLEIQRLHRRLKTTSLYVTHDQVEAMTLADRVVVMNGGVAEQIGTPVEVYEKPASTFVASFIGSpaM 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 238 NMLEASVSEpAQNSIDLDGRQITVQETLAHHPKGKPLTLALRPEAVSLEarkSHDTSLEATIDDVHFLG--SVIRTRviL 315
Cdd:PRK11650 241 NLLDGRVSA-DGAAFELAGGIALPLGGGYRQYAGRKLTLGIRPEHIALS---SAEGGVPLTVDTVELLGadNLAHGR--W 314

                        330       340       350
                 ....*....|....*....|....*....|...
gi 559158796 316 GKNRLSFDTfndPTHPPPQRGDKVTVHFASHDL 348
Cdd:PRK11650 315 GGQPLVVRL---PHQERPAAGSTLWLHLPANQL 344
ABC_Carb_Solutes_like cd03259
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ...
 4-216 6.33e-121

ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213226 [Multi-domain]  Cd Length: 213  Bit Score: 347.20  E-value: 6.33e-121
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQRNIGMVFQA 83
Cdd:cd03259    1 LELKGLSKTYGSVRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILIDGRDVTGVPPERRNIGMVFQD 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  84 YALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSA 163
Cdd:cd03259   81 YALFPHLTVAENIAFGLKLRGVPKAEIRARVRELLELVGLEGLLNRYPHELSGGQQQRVALARALAREPSLLLLDEPLSA 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 559158796 164 LDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIG 216
Cdd:cd03259  161 LDAKLREELREELKELQRELGITTIYVTHDQEEALALADRIAVMNEGRIVQVG 213
potA TIGR01187
spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine ...
 35-351 2.18e-116

spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine/putrescine ABC transporter, ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Polyamines like spermidine and putrescine play vital role in cell proliferation, differentiation, and ion homeostasis. The concentration of polyamines within the cell are regulated by biosynthesis, degradation and transport (uptake and efflux included). [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 162242 [Multi-domain]  Cd Length: 325  Bit Score: 340.24  E-value: 2.18e-116
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   35 LGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQRNIGMVFQAYALFPNMTVAQNVSFGLRVSGKSRSEIDATV 114
Cdd:TIGR01187   2 LGPSGCGKTTLLRLLAGFEQPDSGSIMLDGEDVTNVPPHLRHINMVFQSYALFPHMTVEENVAFGLKMRKVPRAEIKPRV 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  115 KEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSALDAKIRISLREEIRAIQQKLGITTVFVTHDQ 194
Cdd:TIGR01187  82 LEALRLVQLEEFADRKPHQLSGGQQQRVALARALVFKPKILLLDEPLSALDKKLRDQMQLELKTIQEQLGITFVFVTHDQ 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  195 EEALSISDRIVVMHEGRADQIGSPFDIYNRPASRFVASFVGTLNMLEASVSEPAQNSIDLDGRQITVQE--TLAHHPKGK 272
Cdd:TIGR01187 162 EEAMTMSDRIAIMRKGKIAQIGTPEEIYEEPANLFVARFIGEINVFEATVIERKSEQVVLAGVEGRRCDiyTDVPVEKDQ 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  273 PLTLALRPEAVSL--EARKSHDTSLEATIDDVHFLGSVIRTRVIL---GKNRLSFDTFNDPTHPPPQRGDKVTVHFASHD 347
Cdd:TIGR01187 242 PLHVVLRPEKIVIeeEDEANSSNAIIGHVIDITYLGMTLEVHVRLetgQKVLVSEFFNEDDPHMSPSIGDRVGLTWHPGS 321


                  ....
gi 559158796  348 LLVL 351
Cdd:TIGR01187 322 EVVL 325
ABC_CysA_sulfate_importer cd03296
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ...
 6-235 3.40e-113

ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213263 [Multi-domain]  Cd Length: 239  Bit Score: 328.91  E-value: 3.40e-113
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   6 IKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQRNIGMVFQAYA 85
Cdd:cd03296    5 VRNVSKRFGDFVALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFGGEDATDVPVQERNVGFVFQHYA 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  86 LFPNMTVAQNVSFGLRVSGKSR----SEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPL 161
Cdd:cd03296   85 LFRHMTVFDNVAFGLRVKPRSErppeAEIRAKVHELLKLVQLDWLADRYPAQLSGGQRQRVALARALAVEPKVLLLDEPF 164

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 559158796 162 SALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNRPASRFVASFVG 235
Cdd:cd03296  165 GALDAKVRKELRRWLRRLHDELHVTTVFVTHDQEEALEVADRVVVMNKGRIEQVGTPDEVYDHPASPFVYSFLG 238
ABC_MalK_N cd03301
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ...
 4-216 1.57e-112

The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.


Pssm-ID: 213268 [Multi-domain]  Cd Length: 213  Bit Score: 326.13  E-value: 1.57e-112
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQRNIGMVFQA 83
Cdd:cd03301    1 VELENVTKRFGNVTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYIGGRDVTDLPPKDRDIAMVFQN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  84 YALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSA 163
Cdd:cd03301   81 YALYPHMTVYDNIAFGLKLRKVPKDEIDERVREVAELLQIEHLLDRKPKQLSGGQRQRVALGRAIVREPKVFLMDEPLSN 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 559158796 164 LDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIG 216
Cdd:cd03301  161 LDAKLRVQMRAELKRLQQRLGTTTIYVTHDQVEAMTMADRIAVMNDGQIQQIG 213
TauB COG1116
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ...
 1-207 6.74e-106

ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440733 [Multi-domain]  Cd Length: 260  Bit Score: 310.87  E-value: 6.74e-106
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   1 MAFLNIKNLKKSF----GTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNqrn 76
Cdd:COG1116    5 APALELRGVSKRFptggGGVTALDDVSLTVAAGEFVALVGPSGCGKSTLLRLIAGLEKPTSGEVLVDGKPVTGPGPD--- 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  77 IGMVFQAYALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLL 156
Cdd:COG1116   82 RGVVFQEPALLPWLTVLDNVALGLELRGVPKAERRERARELLELVGLAGFEDAYPHQLSGGMRQRVAIARALANDPEVLL 161

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 559158796 157 LDEPLSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVM 207
Cdd:COG1116  162 MDEPFGALDALTRERLQDELLRLWQETGKTVLFVTHDVDEAVFLADRVVVL 212
3a0106s01 TIGR00968
sulfate ABC transporter, ATP-binding protein; [Transport and binding proteins, Anions]
 6-240 9.47e-105

sulfate ABC transporter, ATP-binding protein; [Transport and binding proteins, Anions]


Pssm-ID: 130041 [Multi-domain]  Cd Length: 237  Bit Score: 307.11  E-value: 9.47e-105
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796    6 IKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQRNIGMVFQAYA 85
Cdd:TIGR00968   3 IANISKRFGSFQALDDVNLEVPTGSLVALLGPSGSGKSTLLRIIAGLEQPDSGRIRLNGQDATRVHARDRKIGFVFQHYA 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   86 LFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSALD 165
Cdd:TIGR00968  83 LFKHLTVRDNIAFGLEIRKHPKAKIKARVEELLELVQLEGLGDRYPNQLSGGQRQRVALARALAVEPQVLLLDEPFGALD 162

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 559158796  166 AKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNRPASRFVASFVGTLNML 240
Cdd:TIGR00968 163 AKVRKELRSWLRKLHDEVHVTTVFVTHDQEEAMEVADRIVVMSNGKIEQIGSPDEVYDHPANPFVMSFLGEVNVL 237
PRK10851 PRK10851
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
6-306 5.98e-104

sulfate/thiosulfate ABC transporter ATP-binding protein CysA;


Pssm-ID: 182778 [Multi-domain]  Cd Length: 353  Bit Score: 309.32  E-value: 5.98e-104
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   6 IKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQRNIGMVFQAYA 85
Cdd:PRK10851   5 IANIKKSFGRTQVLNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIRFHGTDVSRLHARDRKVGFVFQHYA 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  86 LFPNMTVAQNVSFGLRV----SGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPL 161
Cdd:PRK10851  85 LFRHMTVFDNIAFGLTVlprrERPNAAAIKAKVTQLLEMVQLAHLADRYPAQLSGGQKQRVALARALAVEPQILLLDEPF 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 162 SALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNRPASRFVASFVGTLNMLE 241
Cdd:PRK10851 165 GALDAQVRKELRRWLRQLHEELKFTSVFVTHDQEEAMEVADRVVVMSQGNIEQAGTPDQVWREPATRFVLEFMGEVNRLQ 244

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 559158796 242 ASVSepaqnsidldGRQITVQetlAHH------PKGK-PLTLALRPEAVSLEARKSHDTSLEATIDDVHFLG 306
Cdd:PRK10851 245 GTIR----------GGQFHVG---AHRwplgytPAYQgPVDLFLRPWEVDISRRTSLDSPLPVQVLEVSPKG 303
PRK11000 PRK11000
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
1-306 1.21e-101

maltose/maltodextrin ABC transporter ATP-binding protein MalK;


Pssm-ID: 182893 [Multi-domain]  Cd Length: 369  Bit Score: 304.26  E-value: 1.21e-101
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   1 MAFLNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQRNIGMV 80
Cdd:PRK11000   1 MASVTLRNVTKAYGDVVISKDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDITSGDLFIGEKRMNDVPPAERGVGMV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  81 FQAYALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEP 160
Cdd:PRK11000  81 FQSYALYPHLSVAENMSFGLKLAGAKKEEINQRVNQVAEVLQLAHLLDRKPKALSGGQRQRVAIGRTLVAEPSVFLLDEP 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 161 LSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNRPASRFVASFVGT--LN 238
Cdd:PRK11000 161 LSNLDAALRVQMRIEISRLHKRLGRTMIYVTHDQVEAMTLADKIVVLDAGRVAQVGKPLELYHYPANRFVAGFIGSpkMN 240

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 559158796 239 MLEASVS--EPAQNSIDLDGRQ---ITVQETLAHhpKGKPLTLALRPEAVsLEARKShDTSLEATIDDVHFLG 306
Cdd:PRK11000 241 FLPVKVTatAIEQVQVELPNRQqvwLPVEGRGVQ--VGANMSLGIRPEHL-LPSDIA-DVTLEGEVQVVEQLG 309
potG PRK11607
putrescine ABC transporter ATP-binding subunit PotG;
4-285 1.81e-101

putrescine ABC transporter ATP-binding subunit PotG;


Pssm-ID: 183226 [Multi-domain]  Cd Length: 377  Bit Score: 304.07  E-value: 1.81e-101
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQRNIGMVFQA 83
Cdd:PRK11607  20 LEIRNLTKSFDGQHAVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIMLDGVDLSHVPPYQRPINMMFQS 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  84 YALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSA 163
Cdd:PRK11607 100 YALFPHMTVEQNIAFGLKQDKLPKAEIASRVNEMLGLVHMQEFAKRKPHQLSGGQRQRVALARSLAKRPKLLLLDEPMGA 179

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 164 LDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNRPASRFVASFVGTLNMLEAS 243
Cdd:PRK11607 180 LDKKLRDRMQLEVVDILERVGVTCVMVTHDQEEAMTMAGRIAIMNRGKFVQIGEPEEIYEHPTTRYSAEFIGSVNVFEGV 259

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|..
gi 559158796 244 VSEPAQNSIDLDGRQITvqetlahHP----------KGKPLTLALRPEAVSL 285
Cdd:PRK11607 260 LKERQEDGLVIDSPGLV-------HPlkvdadasvvDNVPVHVALRPEKIML 304
OpuBA COG1125
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and ...
 6-235 1.29e-100

ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440742 [Multi-domain]  Cd Length: 306  Bit Score: 299.31  E-value: 1.29e-100
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   6 IKNLKKSF-GTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQ--RNIGMVFQ 82
Cdd:COG1125    4 FENVTKRYpDGTVAVDDLSLTIPAGEFTVLVGPSGCGKTTTLRMINRLIEPTSGRILIDGEDIRDLDPVElrRRIGYVIQ 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  83 AYALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLD--HLADRYPYQMSGGQQQRVALARALATKPQVLLLDEP 160
Cdd:COG1125   84 QIGLFPHMTVAENIATVPRLLGWDKERIRARVDELLELVGLDpeEYRDRYPHELSGGQQQRVGVARALAADPPILLMDEP 163

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 559158796 161 LSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNRPASRFVASFVG 235
Cdd:COG1125  164 FGALDPITREQLQDELLRLQRELGKTIVFVTHDIDEALKLGDRIAVMREGRIVQYDTPEEILANPANDFVADFVG 238
ABC_NrtD_SsuB_transporters cd03293
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ...
 4-221 5.58e-100

ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213260 [Multi-domain]  Cd Length: 220  Bit Score: 294.38  E-value: 5.58e-100
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTN----TVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNqrnIGM 79
Cdd:cd03293    1 LEVRNVSKTYGGGggavTALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLVDGEPVTGPGPD---RGY 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  80 VFQAYALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDE 159
Cdd:cd03293   78 VFQQDALLPWLTVLDNVALGLELQGVPKAEARERAEELLELVGLSGFENAYPHQLSGGMRQRVALARALAVDPDVLLLDE 157

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 559158796 160 PLSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRAdQIGSPFDI 221
Cdd:cd03293  158 PFSALDALTREQLQEELLDIWRETGKTVLLVTHDIDEAVFLADRVVVLSARPG-RIVAEVEV 218
tungstate_WtpC NF040840
tungstate ABC transporter ATP-binding protein WtpC;
19-316 1.40e-98

tungstate ABC transporter ATP-binding protein WtpC;


Pssm-ID: 468779 [Multi-domain]  Cd Length: 347  Bit Score: 295.45  E-value: 1.40e-98
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  19 VHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQRNIGMVFQAYALFPNMTVAQNVSF 98
Cdd:NF040840  16 LRDISLEVKEGEYFIILGPSGAGKTVLLELIAGIWPPDSGKIYLDGKDITNLPPEKRGIAYVYQNYMLFPHKTVFENIAF 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  99 GLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSALDAKIRISLREEIRA 178
Cdd:NF040840  96 GLKLRKVPKEEIERKVKEIMELLGISHLLHRKPRTLSGGEQQRVALARALIIEPKLLLLDEPLSALDVQTRDELIREMKR 175

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 179 IQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNRPASRFVASFVGTLNMLEASVSEPAQ-NSIDLDGR 257
Cdd:NF040840 176 WHREFGFTAIHVTHNFEEALSLADRVGIMLNGRLSQVGDVREVFRRPKNEFVARFVGFENIIEGVAEKGGEgTILDTGNI 255

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 559158796 258 QItvqeTLAHHPKGKpLTLALRPEAVSLEARK---SHDTSLEATIDDVHFLGSVIRTRVILG 316
Cdd:NF040840 256 KI----ELPEEKKGK-VRIGIRPEDITISTEKvktSARNEFKGKVEEIEDLGPLVKLTLDVG 312
ABC_ModC_like cd03299
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ...
 4-239 2.32e-94

ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213266 [Multi-domain]  Cd Length: 235  Bit Score: 280.76  E-value: 2.32e-94
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGtNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQRNIGMVFQA 83
Cdd:cd03299    1 LKVENLSKDWK-EFKLKNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKILLNGKDITNLPPEKRDISYVPQN 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  84 YALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSA 163
Cdd:cd03299   80 YALFPHMTVYKNIAYGLKKRKVDKKEIERKVLEIAEMLGIDHLLNRKPETLSGGEQQRVAIARALVVNPKILLLDEPFSA 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 559158796 164 LDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNRPASRFVASFVGTLNM 239
Cdd:cd03299  160 LDVRTKEKLREELKKIRKEFGVTVLHVTHDFEEAWALADKVAIMLNGKLIQVGKPEEVFKKPKNEFVAEFLGFNNI 235
ABC_OpuCA_Osmoprotection cd03295
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ...
 4-235 5.87e-93

ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213262 [Multi-domain]  Cd Length: 242  Bit Score: 277.26  E-value: 5.87e-93
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSF-GTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQ--RNIGMV 80
Cdd:cd03295    1 IEFENVTKRYgGGKKAVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIFIDGEDIREQDPVElrRKIGYV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  81 FQAYALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLD--HLADRYPYQMSGGQQQRVALARALATKPQVLLLD 158
Cdd:cd03295   81 IQQIGLFPHMTVEENIALVPKLLKWPKEKIRERADELLALVGLDpaEFADRYPHELSGGQQQRVGVARALAADPPLLLMD 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 559158796 159 EPLSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNRPASRFVASFVG 235
Cdd:cd03295  161 EPFGALDPITRDQLQEEFKRLQQELGKTIVFVTHDIDEAFRLADRIAIMKNGEIVQVGTPDEILRSPANDFVAEFVG 237
GlnQ COG1126
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ...
 4-227 7.79e-84

ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440743 [Multi-domain]  Cd Length: 239  Bit Score: 254.15  E-value: 7.79e-84
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDV----VNLRPNQRNIGM 79
Cdd:COG1126    2 IEIENLHKSFGDLEVLKGISLDVEKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTITVDGEDLtdskKDINKLRRKVGM 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  80 VFQAYALFPNMTVAQNVSFGLR-VSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLD 158
Cdd:COG1126   82 VFQQFNLFPHLTVLENVTLAPIkVKKMSKAEAEERAMELLERVGLADKADAYPAQLSGGQQQRVAIARALAMEPKVMLFD 161

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 559158796 159 EPLSALD--------AKIRiSLREEiraiqqklGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNRPAS 227
Cdd:COG1126  162 EPTSALDpelvgevlDVMR-DLAKE--------GMTMVVVTHEMGFAREVADRVVFMDGGRIVEEGPPEEFFENPQH 229
MlaF COG1127
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ...
 6-218 2.28e-83

ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440744 [Multi-domain]  Cd Length: 241  Bit Score: 252.98  E-value: 2.28e-83
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   6 IKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQ-----RNIGMV 80
Cdd:COG1127    8 VRNLTKSFGDRVVLDGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSGEILVDGQDITGLSEKElyelrRRIGML 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  81 FQAYALFPNMTVAQNVSFGLRV-SGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDE 159
Cdd:COG1127   88 FQGGALFDSLTVFENVAFPLREhTDLSEAEIRELVLEKLELVGLPGAADKMPSELSGGMRKRVALARALALDPEILLYDE 167

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 559158796 160 PLSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSP 218
Cdd:COG1127  168 PTAGLDPITSAVIDELIRELRDELGLTSVVVTHDLDSAFAIADRVAVLADGKIIAEGTP 226
ABC_MJ0796_LolCDE_FtsE cd03255
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ...
 4-211 7.64e-82

ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.


Pssm-ID: 213222 [Multi-domain]  Cd Length: 218  Bit Score: 248.17  E-value: 7.64e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTN----TVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQR---- 75
Cdd:cd03255    1 IELKNLSKTYGGGgekvQALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDGTDISKLSEKELaafr 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  76 --NIGMVFQAYALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQ 153
Cdd:cd03255   81 rrHIGFVFQSFNLLPDLTALENVELPLLLAGVPKKERRERAEELLERVGLGDRLNHYPSELSGGQQQRVAIARALANDPK 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 559158796 154 VLLLDEPLSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEAlSISDRIVVMHEGR 211
Cdd:cd03255  161 IILADEPTGNLDSETGKEVMELLRELNKEAGTTIVVVTHDPELA-EYADRIIELRDGK 217
ABC_Class3 cd03229
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ...
 4-211 1.48e-81

ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213196 [Multi-domain]  Cd Length: 178  Bit Score: 245.94  E-value: 1.48e-81
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDV----VNLRPNQRNIGM 79
Cdd:cd03229    1 LELKNVSKRYGQKTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIDGEDLtdleDELPPLRRRIGM 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  80 VFQAYALFPNMTVAQNVSFGLrvsgksrseidatvkemlslirldhladrypyqmSGGQQQRVALARALATKPQVLLLDE 159
Cdd:cd03229   81 VFQDFALFPHLTVLENIALGL----------------------------------SGGQQQRVALARALAMDPDVLLLDE 126

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 559158796 160 PLSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGR 211
Cdd:cd03229  127 PTSALDPITRREVRALLKSLQAQLGITVVLVTHDLDEAARLADRVVVLRDGK 178
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
 4-225 1.47e-80

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 254.83  E-value: 1.47e-80
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTN-----TVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQ---- 74
Cdd:COG1123  261 LEVRNLSKRYPVRgkggvRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRPTSGSILFDGKDLTKLSRRSlrel 340

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  75 -RNIGMVFQ--AYALFPNMTVAQNVSFGLRVSGK-SRSEIDATVKEMLSLIRLD-HLADRYPYQMSGGQQQRVALARALA 149
Cdd:COG1123  341 rRRVQMVFQdpYSSLNPRMTVGDIIAEPLRLHGLlSRAERRERVAELLERVGLPpDLADRYPHELSGGQRQRVAIARALA 420

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 559158796 150 TKPQVLLLDEPLSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNRP 225
Cdd:COG1123  421 LEPKLLILDEPTSALDVSVQAQILNLLRDLQRELGLTYLFISHDLAVVRYIADRVAVMYDGRIVEDGPTEEVFANP 496
LolD COG1136
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
4-211 5.54e-80

ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440751 [Multi-domain]  Cd Length: 227  Bit Score: 243.80  E-value: 5.54e-80
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTN----TVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQR---- 75
Cdd:COG1136    5 LELRNLTKSYGTGegevTALRGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVLIDGQDISSLSERELarlr 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  76 --NIGMVFQAYALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQ 153
Cdd:COG1136   85 rrHIGFVFQFFNLLPELTALENVALPLLLAGVSRKERRERARELLERVGLGDRLDHRPSQLSGGQQQRVAIARALVNRPK 164

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 559158796 154 VLLLDEPLSALDAKIRISLREEIRAIQQKLGITTVFVTHDqEEALSISDRIVVMHEGR 211
Cdd:COG1136  165 LILADEPTGNLDSKTGEEVLELLRELNRELGTTIVMVTHD-PELAARADRVIRLRDGR 221
AbcC COG1135
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
6-259 2.70e-78

ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440750 [Multi-domain]  Cd Length: 339  Bit Score: 243.45  E-value: 2.70e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   6 IKNLKKSFGTN----TVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQ-----RN 76
Cdd:COG1135    4 LENLSKTFPTKggpvTALDDVSLTIEKGEIFGIIGYSGAGKSTLIRCINLLERPTSGSVLVDGVDLTALSERElraarRK 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  77 IGMVFQAYALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLL 156
Cdd:COG1135   84 IGMIFQHFNLLSSRTVAENVALPLEIAGVPKAEIRKRVAELLELVGLSDKADAYPSQLSGGQKQRVGIARALANNPKVLL 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 157 LDEPLSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNRPASRFVASFVGT 236
Cdd:COG1135  164 CDEATSALDPETTRSILDLLKDINRELGLTIVLITHEMDVVRRICDRVAVLENGRIVEQGPVLDVFANPQSELTRRFLPT 243

                        250       260
                 ....*....|....*....|...
gi 559158796 237 LNMLEASVSEPAQNSIDLDGRQI 259
Cdd:COG1135  244 VLNDELPEELLARLREAAGGGRL 266
ABC_ModC_molybdenum_transporter cd03297
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ...
 21-216 4.02e-78

ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213264 [Multi-domain]  Cd Length: 214  Bit Score: 238.73  E-value: 4.02e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  21 DFNLAVG---KGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDG------KDVVNLRPNQRNIGMVFQAYALFPNMT 91
Cdd:cd03297   12 DFTLKIDfdlNEEVTGIFGASGAGKSTLLRCIAGLEKPDGGTIVLNGtvlfdsRKKINLPPQQRKIGLVFQQYALFPHLN 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  92 VAQNVSFGLRvsGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSALDAKIRIS 171
Cdd:cd03297   92 VRENLAFGLK--RKRNREDRISVDELLDLLGLDHLLNRYPAQLSGGEKQRVALARALAAQPELLLLDEPFSALDRALRLQ 169

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 559158796 172 LREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIG 216
Cdd:cd03297  170 LLPELKQIKKNLNIPVIFVTHDLSEAEYLADRIVVMEDGRLQYIG 214
ABC_Pro_Gly_Betaine cd03294
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ...
 9-234 4.24e-78

ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213261 [Multi-domain]  Cd Length: 269  Bit Score: 240.62  E-value: 4.24e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   9 LKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQ------RNIGMVFQ 82
Cdd:cd03294   30 ILKKTGQTVGVNDVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIEPTSGKVLIDGQDIAAMSRKElrelrrKKISMVFQ 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  83 AYALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLS 162
Cdd:cd03294  110 SFALLPHRTVLENVAFGLEVQGVPRAEREERAAEALELVGLEGWEHKYPDELSGGMQQRVGLARALAVDPDILLMDEAFS 189

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 559158796 163 ALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNRPASRFVASFV 234
Cdd:cd03294  190 ALDPLIRREMQDELLRLQAELQKTIVFITHDLDEALRLGDRIAIMKDGRLVQVGTPEEILTNPANDYVREFF 261
ABC_Org_Solvent_Resistant cd03261
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ...
 6-221 6.52e-77

ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213228 [Multi-domain]  Cd Length: 235  Bit Score: 236.24  E-value: 6.52e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   6 IKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQ-----RNIGMV 80
Cdd:cd03261    3 LRGLTKSFGGRTVLKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDGEDISGLSEAElyrlrRRMGML 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  81 FQAYALFPNMTVAQNVSFGLRVSGK-SRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDE 159
Cdd:cd03261   83 FQSGALFDSLTVFENVAFPLREHTRlSEEEIREIVLEKLEAVGLRGAEDLYPAELSGGMKKRVALARALALDPELLLYDE 162

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 559158796 160 PLSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDI 221
Cdd:cd03261  163 PTAGLDPIASGVIDDLIRSLKKELGLTSIMVTHDLDTAFAIADRIAVLYDGKIVAEGTPEEL 224
ABC_MetN_methionine_transporter cd03258
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ...
 4-225 1.58e-75

ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213225 [Multi-domain]  Cd Length: 233  Bit Score: 232.47  E-value: 1.58e-75
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTN----TVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVV-----NLRPNQ 74
Cdd:cd03258    2 IELKNVSKVFGDTggkvTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLVDGTDLTllsgkELRKAR 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  75 RNIGMVFQAYALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQV 154
Cdd:cd03258   82 RRIGMIFQHFNLLSSRTVFENVALPLEIAGVPKAEIEERVLELLELVGLEDKADAYPAQLSGGQKQRVGIARALANNPKV 161

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 559158796 155 LLLDEPLSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNRP 225
Cdd:cd03258  162 LLCDEATSALDPETTQSILALLRDINRELGLTIVLITHEMEVVKRICDRVAVMEKGEVVEEGTVEEVFANP 232
ModC COG4148
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ...
 8-303 7.27e-75

ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis


Pssm-ID: 443319 [Multi-domain]  Cd Length: 358  Bit Score: 234.99  E-value: 7.27e-75
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   8 NLKKSFGtntvvhDFNLAV-----GKGefVSFL-GPSGCGKTTVLRMIAGFETPDNGSIEIDGKDV------VNLRPNQR 75
Cdd:COG4148    6 DFRLRRG------GFTLDVdftlpGRG--VTALfGPSGSGKTTLLRAIAGLERPDSGRIRLGGEVLqdsargIFLPPHRR 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  76 NIGMVFQAYALFPNMTVAQNVSFGLRVSGKSRSEID-ATVKEMLsliRLDHLADRYPYQMSGGQQQRVALARALATKPQV 154
Cdd:COG4148   78 RIGYVFQEARLFPHLSVRGNLLYGRKRAPRAERRISfDEVVELL---GIGHLLDRRPATLSGGERQRVAIGRALLSSPRL 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 155 LLLDEPLSALDAKirisLREEI----RAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNRPASRFV 230
Cdd:COG4148  155 LLMDEPLAALDLA----RKAEIlpylERLRDELDIPILYVSHSLDEVARLADHVVLLEQGRVVASGPLAEVLSRPDLLPL 230

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 231 ASFVGTLNMLEASVSEPAQN----SIDLDGRQITVQetLAHHPKGKPLTLALRPEAVSLEARKSHDTS----LEATIDDV 302
Cdd:COG4148  231 AGGEEAGSVLEATVAAHDPDygltRLALGGGRLWVP--RLDLPPGTRVRVRIRARDVSLALEPPEGSSilniLPGRVVEI 308


                 .
gi 559158796 303 H 303
Cdd:COG4148  309 E 309
proV TIGR01186
glycine betaine/L-proline transport ATP binding subunit; This model describes the glycine ...
 11-246 1.03e-74

glycine betaine/L-proline transport ATP binding subunit; This model describes the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Functionally, this transport system is involved in osmoregulation. Under conditions of stress, the organism recruits these transport system to accumulate glycine betaine and other solutes which offer osmo-protection. It has been demonstrated that glycine betaine uptake is accompanied by symport with sodium ions. The locus has been named variously as proU or opuA. A gene library from L.lactis functionally complements an E.coli proU mutant. The comlementing locus is similar to a opuA locus in B.sutlis. This clarifies the differences in nomenclature. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 130254 [Multi-domain]  Cd Length: 363  Bit Score: 235.13  E-value: 1.03e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   11 KSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQ------RNIGMVFQAY 84
Cdd:TIGR01186   1 KKTGGKKGVNDADLAIAKGEIFVIMGLSGSGKSTTVRMLNRLIEPTAGQIFIDGENIMKQSPVElrevrrKKIGMVFQQF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   85 ALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSAL 164
Cdd:TIGR01186  81 ALFPHMTILQNTSLGPELLGWPEQERKEKALELLKLVGLEEYEHRYPDELSGGMQQRVGLARALAAEPDILLMDEAFSAL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  165 DAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNRPASRFVASFVGTLNMLEASV 244
Cdd:TIGR01186 161 DPLIRDSMQDELKKLQATLQKTIVFITHDLDEAIRIGDRIVIMKAGEIVQVGTPDEILRNPANEYVEEFIGKVDLSQVFD 240


                  ..
gi 559158796  245 SE 246
Cdd:TIGR01186 241 AE 242
CcmA COG1131
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
4-211 1.18e-74

ABC-type multidrug transport system, ATPase component [Defense mechanisms];


Pssm-ID: 440746 [Multi-domain]  Cd Length: 236  Bit Score: 230.34  E-value: 1.18e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPN-QRNIGMVFQ 82
Cdd:COG1131    1 IEVRGLTKRYGDKTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVLGEDVARDPAEvRRRIGYVPQ 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  83 AYALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLS 162
Cdd:COG1131   81 EPALYPDLTVRENLRFFARLYGLPRKEARERIDELLELFGLTDAADRKVGTLSGGMKQRLGLALALLHDPELLILDEPTS 160

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 559158796 163 ALDAKIRISLREEIRAIQQKlGITTVFVTHDQEEALSISDRIVVMHEGR 211
Cdd:COG1131  161 GLDPEARRELWELLRELAAE-GKTVLLSTHYLEEAERLCDRVAIIDKGR 208
EcfA2 COG1122
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ...
 4-225 2.13e-74

Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];


Pssm-ID: 440739 [Multi-domain]  Cd Length: 230  Bit Score: 229.53  E-value: 2.13e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSF-GTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQ--RNIGMV 80
Cdd:COG1122    1 IELENLSFSYpGGTPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVDGKDITKKNLRElrRKVGLV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  81 FQ--AYALFpNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLD 158
Cdd:COG1122   81 FQnpDDQLF-APTVEEDVAFGPENLGLPREEIRERVEEALELVGLEHLADRPPHELSGGQKQRVAIAGVLAMEPEVLVLD 159

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 559158796 159 EPLSALDAKIRISLREEIRAIQQKlGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNRP 225
Cdd:COG1122  160 EPTAGLDPRGRRELLELLKRLNKE-GKTVIIVTHDLDLVAELADRVIVLDDGRIVADGTPREVFSDY 225
ABC_HisP_GlnQ cd03262
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ...
 4-211 3.68e-74

ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.


Pssm-ID: 213229 [Multi-domain]  Cd Length: 213  Bit Score: 228.18  E-value: 3.68e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPN----QRNIGM 79
Cdd:cd03262    1 IEIKNLHKSFGDFHVLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIIDGLKLTDDKKNinelRQKVGM 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  80 VFQAYALFPNMTVAQNVSFGLR-VSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLD 158
Cdd:cd03262   81 VFQQFNLFPHLTVLENITLAPIkVKGMSKAEAEERALELLEKVGLADKADAYPAQLSGGQQQRVAIARALAMNPKVMLFD 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 559158796 159 EPLSALDAKIRISLREEIRAIQQKlGITTVFVTHDQEEALSISDRIVVMHEGR 211
Cdd:cd03262  161 EPTSALDPELVGEVLDVMKDLAEE-GMTMVVVTHEMGFAREVADRVIFMDDGR 212
ThiQ COG3840
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
4-236 5.40e-72

ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];


Pssm-ID: 443051 [Multi-domain]  Cd Length: 232  Bit Score: 223.48  E-value: 5.40e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVvhDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQRNIGMVFQA 83
Cdd:COG3840    2 LRLDDLTYRYGDFPL--RFDLTIAAGERVAILGPSGAGKSTLLNLIAGFLPPDSGRILWNGQDLTALPPAERPVSMLFQE 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  84 YALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSA 163
Cdd:COG3840   80 NNLFPHLTVAQNIGLGLRPGLKLTAEQRAQVEQALERVGLAGLLDRLPGQLSGGQRQRVALARCLVRKRPILLLDEPFSA 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 559158796 164 LDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNRPASRFVASFVGT 236
Cdd:COG3840  160 LDPALRQEMLDLVDELCRERGLTVLMVTHDPEDAARIADRVLLVADGRIAADGPTAALLDGEPPPALAAYLGI 232
DppF COG1124
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
 4-227 1.90e-71

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440741 [Multi-domain]  Cd Length: 248  Bit Score: 222.76  E-value: 1.90e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGT----NTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVN--LRPNQRNI 77
Cdd:COG1124    2 LEVRNLSVSYGQggrrVPVLKDVSLEVAPGESFGLVGESGSGKSTLLRALAGLERPWSGEVTFDGRPVTRrrRKAFRRRV 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  78 GMVFQAY--ALFPNMTVAQNVSFGLRVSGksRSEIDATVKEMLSLIRLD-HLADRYPYQMSGGQQQRVALARALATKPQV 154
Cdd:COG1124   82 QMVFQDPyaSLHPRHTVDRILAEPLRIHG--LPDREERIAELLEQVGLPpSFLDRYPHQLSGGQRQRVAIARALILEPEL 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 559158796 155 LLLDEPLSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNRPAS 227
Cdd:COG1124  160 LLLDEPTSALDVSVQAEILNLLKDLREERGLTYLFVSHDLAVVAHLCDRVAVMQNGRIVEELTVADLLAGPKH 232
ABC_NikE_OppD_transporters cd03257
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ...
 4-211 2.65e-69

ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.


Pssm-ID: 213224 [Multi-domain]  Cd Length: 228  Bit Score: 216.60  E-value: 2.65e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSF----GTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQRN--- 76
Cdd:cd03257    2 LEVKNLSVSFptggGSVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFDGKDLLKLSRRLRKirr 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  77 --IGMVFQAY--ALFPNMTVAQNVSFGLRVSGKSR--SEIDATVKEMLSLIRLD-HLADRYPYQMSGGQQQRVALARALA 149
Cdd:cd03257   82 keIQMVFQDPmsSLNPRMTIGEQIAEPLRIHGKLSkkEARKEAVLLLLVGVGLPeEVLNRYPHELSGGQRQRVAIARALA 161

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 559158796 150 TKPQVLLLDEPLSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGR 211
Cdd:cd03257  162 LNPKLLIADEPTSALDVSVQAQILDLLKKLQEELGLTLLFITHDLGVVAKIADRVAVMYAGK 223
TauB COG4525
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];
1-231 8.18e-69

ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443596 [Multi-domain]  Cd Length: 262  Bit Score: 216.27  E-value: 8.18e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   1 MAFLNIKNLKKSFG----TNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQrn 76
Cdd:COG4525    1 MSMLTVRHVSVRYPgggqPQPALQDVSLTIESGEFVVALGASGCGKTTLLNLIAGFLAPSSGEITLDGVPVTGPGADR-- 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  77 iGMVFQAYALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLL 156
Cdd:COG4525   79 -GVVFQKDALLPWLNVLDNVAFGLRLRGVPKAERRARAEELLALVGLADFARRRIWQLSGGMRQRVGIARALAADPRFLL 157

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 559158796 157 LDEPLSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVM--HEGR-ADQIGSPFdiynrpASRFVA 231
Cdd:COG4525  158 MDEPFGALDALTREQMQELLLDVWQRTGKGVFLITHSVEEALFLATRLVVMspGPGRiVERLELDF------SRRFLA 229
FtsE COG2884
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
6-211 1.25e-67

Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442130 [Multi-domain]  Cd Length: 223  Bit Score: 211.83  E-value: 1.25e-67
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   6 IKNLKKSFGTN-TVVHDFNLAVGKGEFVsFL-GPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQ-----RNIG 78
Cdd:COG2884    4 FENVSKRYPGGrEALSDVSLEIEKGEFV-FLtGPSGAGKSTLLKLLYGEERPTSGQVLVNGQDLSRLKRREipylrRRIG 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  79 MVFQAYALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLD 158
Cdd:COG2884   83 VVFQDFRLLPDRTVYENVALPLRVTGKSRKEIRRRVREVLDLVGLSDKAKALPHELSGGEQQRVAIARALVNRPELLLAD 162

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 559158796 159 EPLSALDAK--IRI-SLREEIRaiqqKLGITTVFVTHDQEEALSISDRIVVMHEGR 211
Cdd:COG2884  163 EPTGNLDPEtsWEImELLEEIN----RRGTTVLIATHDLELVDRMPKRVLELEDGR 214
ABC_cobalt_CbiO_domain1 cd03225
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ...
 6-211 2.59e-67

First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213192 [Multi-domain]  Cd Length: 211  Bit Score: 210.79  E-value: 2.59e-67
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   6 IKNLKKSFGTNT--VVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQ--RNIGMVF 81
Cdd:cd03225    2 LKNLSFSYPDGArpALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDGKDLTKLSLKElrRKVGLVF 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  82 QayalFP-----NMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLL 156
Cdd:cd03225   82 Q----NPddqffGPTVEEEVAFGLENLGLPEEEIEERVEEALELVGLEGLRDRSPFTLSGGQKQRVAIAGVLAMDPDILL 157

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 559158796 157 LDEPLSALDAKIRISLREEIRAIQQKlGITTVFVTHDQEEALSISDRIVVMHEGR 211
Cdd:cd03225  158 LDEPTAGLDPAGRRELLELLKKLKAE-GKTIIIVTHDLDLLLELADRVIVLEDGK 211
glnQ PRK09493
glutamine ABC transporter ATP-binding protein GlnQ;
4-233 7.95e-67

glutamine ABC transporter ATP-binding protein GlnQ;


Pssm-ID: 181906 [Multi-domain]  Cd Length: 240  Bit Score: 210.72  E-value: 7.95e-67
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQRNI----GM 79
Cdd:PRK09493   2 IEFKNVSKHFGPTQVLHNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITSGDLIVDGLKVNDPKVDERLIrqeaGM 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  80 VFQAYALFPNMTVAQNVSFG-LRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLD 158
Cdd:PRK09493  82 VFQQFYLFPHLTALENVMFGpLRVRGASKEEAEKQARELLAKVGLAERAHHYPSELSGGQQQRVAIARALAVKPKLMLFD 161

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 559158796 159 EPLSALDAKirisLREEIRAIQQKL---GITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNRPASRFVASF 233
Cdd:PRK09493 162 EPTSALDPE----LRHEVLKVMQDLaeeGMTMVIVTHEIGFAEKVASRLIFIDKGRIAEDGDPQVLIKNPPSQRLQEF 235
FepC COG1120
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ...
 4-218 1.35e-65

ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];


Pssm-ID: 440737 [Multi-domain]  Cd Length: 254  Bit Score: 207.97  E-value: 1.35e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQ--RNIGMVF 81
Cdd:COG1120    2 LEAENLSVGYGGRPVLDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLLDGRDLASLSRRElaRRIAYVP 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  82 QAYALFPNMTVAQNVSFG----LRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLL 157
Cdd:COG1120   82 QEPPAPFGLTVRELVALGryphLGLFGRPSAEDREAVEEALERTGLEHLADRPVDELSGGERQRVLIARALAQEPPLLLL 161

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 559158796 158 DEPLSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSP 218
Cdd:COG1120  162 DEPTSHLDLAHQLEVLELLRRLARERGRTVVMVLHDLNLAARYADRLVLLKDGRIVAQGPP 222
LivG COG0411
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ...
 1-226 2.75e-65

ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];


Pssm-ID: 440180 [Multi-domain]  Cd Length: 257  Bit Score: 207.20  E-value: 2.75e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   1 MAFLNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQRN---I 77
Cdd:COG0411    2 DPLLEVRGLTKRFGGLVAVDDVSLEVERGEIVGLIGPNGAGKTTLFNLITGFYRPTSGRILFDGRDITGLPPHRIArlgI 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  78 GMVFQAYALFPNMTVAQNV---------------SFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRV 142
Cdd:COG0411   82 ARTFQNPRLFPELTVLENVlvaaharlgrgllaaLLRLPRARREEREARERAEELLERVGLADRADEPAGNLSYGQQRRL 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 143 ALARALATKPQVLLLDEPLSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGR--ADqiGSPFD 220
Cdd:COG0411  162 EIARALATEPKLLLLDEPAAGLNPEETEELAELIRRLRDERGITILLIEHDMDLVMGLADRIVVLDFGRviAE--GTPAE 239


                 ....*.
gi 559158796 221 IYNRPA 226
Cdd:COG0411  240 VRADPR 245
metN PRK11153
DL-methionine transporter ATP-binding subunit; Provisional
 6-232 1.04e-64

DL-methionine transporter ATP-binding subunit; Provisional


Pssm-ID: 236863 [Multi-domain]  Cd Length: 343  Bit Score: 208.50  E-value: 1.04e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   6 IKNLKKSFGTN----TVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQ-----RN 76
Cdd:PRK11153   4 LKNISKVFPQGgrtiHALNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGRVLVDGQDLTALSEKElrkarRQ 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  77 IGMVFQAYALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLL 156
Cdd:PRK11153  84 IGMIFQHFNLLSSRTVFDNVALPLELAGTPKAEIKARVTELLELVGLSDKADRYPAQLSGGQKQRVAIARALASNPKVLL 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 157 LDEPLSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNRP----ASRFVAS 232
Cdd:PRK11153 164 CDEATSALDPATTRSILELLKDINRELGLTIVLITHEMDVVKRICDRVAVIDAGRLVEQGTVSEVFSHPkhplTREFIQS 243
ABC_PstB_phosphate_transporter cd03260
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ...
 4-218 1.11e-64

ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).


Pssm-ID: 213227 [Multi-domain]  Cd Length: 227  Bit Score: 204.72  E-value: 1.11e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGF-----ETPDNGSIEIDGKDVVNLRPN----Q 74
Cdd:cd03260    1 IELRDLNVYYGDKHALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRLndlipGAPDEGEVLLDGKDIYDLDVDvlelR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  75 RNIGMVFQAYALFPnMTVAQNVSFGLRVSG-KSRSEIDATVKEMLSLIRL-DHLADR-YPYQMSGGQQQRVALARALATK 151
Cdd:cd03260   81 RRVGMVFQKPNPFP-GSIYDNVAYGLRLHGiKLKEELDERVEEALRKAALwDEVKDRlHALGLSGGQQQRLCLARALANE 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 559158796 152 PQVLLLDEPLSALD----AKIrislrEE-IRAIQQKlgITTVFVTHDQEEALSISDRIVVMHEGRADQIGSP 218
Cdd:cd03260  160 PEVLLLDEPTSALDpistAKI-----EElIAELKKE--YTIVIVTHNMQQAARVADRTAFLLNGRLVEFGPT 224
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
 4-227 1.15e-64

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 213.23  E-value: 1.15e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSF--GTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFeTPDN----GSIEIDGKDVVNLRPNQR-- 75
Cdd:COG1123    5 LEVRDLSVRYpgGDVPAVDGVSLTIAPGETVALVGESGSGKSTLALALMGL-LPHGgrisGEVLLDGRDLLELSEALRgr 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  76 NIGMVFQ--AYALFPnMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQ 153
Cdd:COG1123   84 RIGMVFQdpMTQLNP-VTVGDQIAEALENLGLSRAEARARVLELLEAVGLERRLDRYPHQLSGGQRQRVAIAMALALDPD 162

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 559158796 154 VLLLDEPLSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNRPAS 227
Cdd:COG1123  163 LLIADEPTTALDVTTQAEILDLLRELQRERGTTVLLITHDLGVVAEIADRVVVMDDGRIVEDGPPEEILAAPQA 236
NatA COG4555
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ...
 4-224 1.04e-63

ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 443618 [Multi-domain]  Cd Length: 243  Bit Score: 202.78  E-value: 1.04e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRP-NQRNIGMVFQ 82
Cdd:COG4555    2 IEVENLSKKYGKVPALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILIDGEDVRKEPReARRQIGVLPD 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  83 AYALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLS 162
Cdd:COG4555   82 ERGLYDRLTVRENIRYFAELYGLFDEELKKRIEELIELLGLEEFLDRRVGELSTGMKKKVALARALVHDPKVLLLDEPTN 161

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 559158796 163 ALDAKIRISLREEIRAIqQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNR 224
Cdd:COG4555  162 GLDVMARRLLREILRAL-KKEGKTVLFSSHIMQEVEALCDRVVILHKGKVVAQGSLDELREE 222
artP PRK11124
arginine transporter ATP-binding subunit; Provisional
 6-211 1.87e-63

arginine transporter ATP-binding subunit; Provisional


Pssm-ID: 182980 [Multi-domain]  Cd Length: 242  Bit Score: 202.17  E-value: 1.87e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   6 IKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEI-----------DGKDVVNLRpnq 74
Cdd:PRK11124   5 LNGINCFYGAHQALFDITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLNIagnhfdfsktpSDKAIRELR--- 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  75 RNIGMVFQAYALFPNMTVAQN-VSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQ 153
Cdd:PRK11124  82 RNVGMVFQQYNLWPHLTVQQNlIEAPCRVLGLSKDQALARAEKLLERLRLKPYADRFPLHLSGGQQQRVAIARALMMEPQ 161

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 559158796 154 VLLLDEPLSALDAKIRISLREEIRAIQQKlGITTVFVTHDQEEALSISDRIVVMHEGR 211
Cdd:PRK11124 162 VLLFDEPTAALDPEITAQIVSIIRELAET-GITQVIVTHEVEVARKTASRVVYMENGH 218
ntrCD TIGR01184
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ...
 21-228 4.89e-63

nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]


Pssm-ID: 130252 [Multi-domain]  Cd Length: 230  Bit Score: 200.38  E-value: 4.89e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   21 DFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQRnigMVFQAYALFPNMTVAQNVSFGL 100
Cdd:TIGR01184   3 GVNLTIQQGEFISLIGHSGCGKSTLLNLISGLAQPTSGGVILEGKQITEPGPDRM---VVFQNYSLLPWLTVRENIALAV 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  101 R--VSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSALDAKIRISLREEIRA 178
Cdd:TIGR01184  80 DrvLPDLSKSERRAIVEEHIALVGLTEAADKRPGQLSGGMKQRVAIARALSIRPKVLLLDEPFGALDALTRGNLQEELMQ 159

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 559158796  179 IQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDI-YNRPASR 228
Cdd:TIGR01184 160 IWEEHRVTVLMVTHDVDEALLLSDRVVMLTNGPAANIGQILEVpFPRPRDR 210
DppD COG0444
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
 4-226 1.71e-62

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440213 [Multi-domain]  Cd Length: 320  Bit Score: 202.21  E-value: 1.71e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTN----TVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETP---DNGSIEIDGKDVVNLRPNQ-- 74
Cdd:COG0444    2 LEVRNLKVYFPTRrgvvKAVDGVSFDVRRGETLGLVGESGSGKSTLARAILGLLPPpgiTSGEILFDGEDLLKLSEKElr 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  75 ----RNIGMVFQ-AY-ALFPNMTVAQNVSFGLRVSGK-SRSEIDATVKEMLSLIRLD---HLADRYPYQMSGGQQQRVAL 144
Cdd:COG0444   82 kirgREIQMIFQdPMtSLNPVMTVGDQIAEPLRIHGGlSKAEARERAIELLERVGLPdpeRRLDRYPHELSGGMRQRVMI 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 145 ARALATKPQVLLLDEPLSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNR 224
Cdd:COG0444  162 ARALALEPKLLIADEPTTALDVTIQAQILNLLKDLQRELGLAILFITHDLGVVAEIADRVAVMYAGRIVEEGPVEELFEN 241


                 ..
gi 559158796 225 PA 226
Cdd:COG0444  242 PR 243
ABC_Mj1267_LivG_branched cd03219
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ...
 4-226 2.14e-62

ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).


Pssm-ID: 213186 [Multi-domain]  Cd Length: 236  Bit Score: 199.20  E-value: 2.14e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQRN---IGMV 80
Cdd:cd03219    1 LEVRGLTKRFGGLVALDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSVLFDGEDITGLPPHEIArlgIGRT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  81 FQAYALFPNMTVAQNV----------SFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALAT 150
Cdd:cd03219   81 FQIPRLFPELTVLENVmvaaqartgsGLLLARARREEREARERAEELLERVGLADLADRPAGELSYGQQRRLEIARALAT 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 559158796 151 KPQVLLLDEPLSALDAKIRISLREEIRAIQQKlGITTVFVTHDQEEALSISDRIVVMHEGR--ADqiGSPFDIYNRPA 226
Cdd:cd03219  161 DPKLLLLDEPAAGLNPEETEELAELIRELRER-GITVLLVEHDMDVVMSLADRVTVLDQGRviAE--GTPDEVRNNPR 235
ECF_ATPase_2 TIGR04521
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...
 4-225 7.07e-62

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the downstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 275314 [Multi-domain]  Cd Length: 277  Bit Score: 199.21  E-value: 7.07e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796    4 LNIKNLKKSFGTNT-----VVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDV-----VNLRPN 73
Cdd:TIGR04521   1 IKLKNVSYIYQPGTpfekkALDDVSLTIEDGEFVAIIGHTGSGKSTLIQHLNGLLKPTSGTVTIDGRDItakkkKKLKDL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   74 QRNIGMVFQ--AYALFPNmTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDH-LADRYPYQMSGGQQQRVALARALAT 150
Cdd:TIGR04521  81 RKKVGLVFQfpEHQLFEE-TVYKDIAFGPKNLGLSEEEAEERVKEALELVGLDEeYLERSPFELSGGQMRRVAIAGVLAM 159

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 559158796  151 KPQVLLLDEPLSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNRP 225
Cdd:TIGR04521 160 EPEVLILDEPTAGLDPKGRKEILDLFKRLHKEKGLTVILVTHSMEDVAEYADRVIVMHKGKIVLDGTPREVFSDV 234
AppF COG4608
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ...
 4-226 1.95e-61

ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443658 [Multi-domain]  Cd Length: 329  Bit Score: 199.57  E-value: 1.95e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSF--------GTNTVVH---DFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVN--- 69
Cdd:COG4608    8 LEVRDLKKHFpvrgglfgRTVGVVKavdGVSFDIRRGETLGLVGESGCGKSTLGRLLLRLEEPTSGEILFDGQDITGlsg 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  70 --LRPNQRNIGMVFQ-AYA-LFPNMTVAQNVSFGLRVSG-KSRSEIDATVKEMLSLIRL--DHlADRYPYQMSGGQQQRV 142
Cdd:COG4608   88 reLRPLRRRMQMVFQdPYAsLNPRMTVGDIIAEPLRIHGlASKAERRERVAELLELVGLrpEH-ADRYPHEFSGGQRQRI 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 143 ALARALATKPQVLLLDEPLSALDAKIR---ISLREEiraIQQKLGITTVFVTHDqeeaLS----ISDRIVVMHEGRADQI 215
Cdd:COG4608  167 GIARALALNPKLIVCDEPVSALDVSIQaqvLNLLED---LQDELGLTYLFISHD----LSvvrhISDRVAVMYLGKIVEI 239

                        250
                 ....*....|.
gi 559158796 216 GSPFDIYNRPA 226
Cdd:COG4608  240 APRDELYARPL 250
ABC_DR_subfamily_A cd03230
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ...
 4-211 4.26e-61

ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213197 [Multi-domain]  Cd Length: 173  Bit Score: 193.38  E-value: 4.26e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPN-QRNIGMVFQ 82
Cdd:cd03230    1 IEVRNLSKRYGKKTALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKVLGKDIKKEPEEvKRRIGYLPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  83 AYALFPNMTVAQNVSFglrvsgksrseidatvkemlslirldhladrypyqmSGGQQQRVALARALATKPQVLLLDEPLS 162
Cdd:cd03230   81 EPSLYENLTVRENLKL------------------------------------SGGMKQRLALAQALLHDPELLILDEPTS 124

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 559158796 163 ALDAKIRISLREEIRAIQQKlGITTVFVTHDQEEALSISDRIVVMHEGR 211
Cdd:cd03230  125 GLDPESRREFWELLRELKKE-GKTILLSSHILEEAERLCDRVAILNNGR 172
PhnC COG3638
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and ...
 4-211 1.15e-60

ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 442855 [Multi-domain]  Cd Length: 249  Bit Score: 194.89  E-value: 1.15e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSF-GTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQ-----RNI 77
Cdd:COG3638    3 LELRNLSKRYpGGTPALDDVSLEIERGEFVALIGPSGAGKSTLLRCLNGLVEPTSGEILVDGQDVTALRGRAlrrlrRRI 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  78 GMVFQAYALFPNMTVAQNVSFGL--RVSG-KS------RSEIDAtVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARAL 148
Cdd:COG3638   83 GMIFQQFNLVPRLSVLTNVLAGRlgRTSTwRSllglfpPEDRER-ALEALERVGLADKAYQRADQLSGGQQQRVAIARAL 161

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 559158796 149 ATKPQVLLLDEPLSALD---AKIRISLreeIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGR 211
Cdd:COG3638  162 VQEPKLILADEPVASLDpktARQVMDL---LRRIAREDGITVVVNLHQVDLARRYADRIIGLRDGR 224
ArtP COG4161
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
6-211 6.28e-60

ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443326 [Multi-domain]  Cd Length: 242  Bit Score: 192.92  E-value: 6.28e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   6 IKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDG-----------KDVVNLRpnq 74
Cdd:COG4161    5 LKNINCFYGSHQALFDINLECPSGETLVLLGPSGAGKSSLLRVLNLLETPDSGQLNIAGhqfdfsqkpseKAIRLLR--- 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  75 RNIGMVFQAYALFPNMTVAQN-VSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQ 153
Cdd:COG4161   82 QKVGMVFQQYNLWPHLTVMENlIEAPCKVLGLSKEQAREKAMKLLARLRLTDKADRFPLHLSGGQQQRVAIARALMMEPQ 161

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 559158796 154 VLLLDEPLSALDAKIRISLREEIRAIQQKlGITTVFVTHDQEEALSISDRIVVMHEGR 211
Cdd:COG4161  162 VLLFDEPTAALDPEITAQVVEIIRELSQT-GITQVIVTHEVEFARKVASQVVYMEKGR 218
YnjD COG4136
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ...
 4-209 1.43e-59

ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];


Pssm-ID: 443311 [Multi-domain]  Cd Length: 211  Bit Score: 190.77  E-value: 1.43e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPD---NGSIEIDGKDVVNLRPNQRNIGMV 80
Cdd:COG4136    2 LSLENLTITLGGRPLLAPLSLTVAPGEILTLMGPSGSGKSTLLAAIAGTLSPAfsaSGEVLLNGRRLTALPAEQRRIGIL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  81 FQAYALFPNMTVAQNVSFGLRvSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEP 160
Cdd:COG4136   82 FQDDLLFPHLSVGENLAFALP-PTIGRAQRRARVEQALEEAGLAGFADRDPATLSGGQRARVALLRALLAEPRALLLDEP 160

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 559158796 161 LSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISdRIVVMHE 209
Cdd:COG4136  161 FSKLDAALRAQFREFVFEQIRQRGIPALLVTHDEEDAPAAG-RVLDLGN 208
ABC_ATP_DarD NF038007
darobactin export ABC transporter ATP-binding protein;
4-211 3.19e-58

darobactin export ABC transporter ATP-binding protein;


Pssm-ID: 411600 [Multi-domain]  Cd Length: 218  Bit Score: 187.62  E-value: 3.19e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNT----VVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQRN--- 76
Cdd:NF038007   2 LNMQNAEKCYITKTiktkVLNHLNFSVEKGDFVSIMGPSGSGKSTLLNIIGMFDSLDSGSLTLAGKEVTNLSYSQKIilr 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  77 ---IGMVFQAYALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQ 153
Cdd:NF038007  82 relIGYIFQSFNLIPHLSIFDNVALPLKYRGVAKKERIERVNQVLNLFGIDNRRNHKPMQLSGGQQQRVAIARAMVSNPA 161

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 559158796 154 VLLLDEPLSALDAKIRISLREEIRAIQQKlGITTVFVTHdQEEALSISDRIVVMHEGR 211
Cdd:NF038007 162 LLLADEPTGNLDSKNARAVLQQLKYINQK-GTTIIMVTH-SDEASTYGNRIINMKDGK 217
PstB COG1117
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ...
 4-211 8.96e-58

ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440734 [Multi-domain]  Cd Length: 258  Bit Score: 187.94  E-value: 8.96e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLR-------MIAGFETpdNGSIEIDGK-------DVVN 69
Cdd:COG1117   12 IEVRNLNVYYGDKQALKDINLDIPENKVTALIGPSGCGKSTLLRclnrmndLIPGARV--EGEILLDGEdiydpdvDVVE 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  70 LRpnqRNIGMVFQAYALFPnMTVAQNVSFGLRVSG-KSRSEIDATVKEmlSLIRL---DHLADR---YPYQMSGGQQQRV 142
Cdd:COG1117   90 LR---RRVGMVFQKPNPFP-KSIYDNVAYGLRLHGiKSKSELDEIVEE--SLRKAalwDEVKDRlkkSALGLSGGQQQRL 163

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 559158796 143 ALARALATKPQVLLLDEPLSALD----AKIrislrEE-IRAIQQKLGIttVFVTHDQEEALSISDRIVVMHEGR 211
Cdd:COG1117  164 CIARALAVEPEVLLMDEPTSALDpistAKI-----EElILELKKDYTI--VIVTHNMQQAARVSDYTAFFYLGE 230
ABC_Iron-Siderophores_B12_Hemin cd03214
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ...
 6-216 7.64e-57

ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.


Pssm-ID: 213181 [Multi-domain]  Cd Length: 180  Bit Score: 182.64  E-value: 7.64e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   6 IKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQRnigmvfqaya 85
Cdd:cd03214    2 VENLSVGYGGRTVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLDGKDLASLSPKEL---------- 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  86 lfpnmtvAQNVSFglrvsgksrseidatVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSALD 165
Cdd:cd03214   72 -------ARKIAY---------------VPQALELLGLAHLADRPFNELSGGERQRVLLARALAQEPPILLLDEPTSHLD 129

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 559158796 166 AKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIG 216
Cdd:cd03214  130 IAHQIELLELLRRLARERGKTVVMVLHDLNLAARYADRVILLKDGRIVAQG 180
modC_ABC TIGR02142
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ...
 8-299 4.82e-56

molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]


Pssm-ID: 131197 [Multi-domain]  Cd Length: 354  Bit Score: 186.47  E-value: 4.82e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796    8 NLKKSFGTNTVvhDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDV------VNLRPNQRNIGMVF 81
Cdd:TIGR02142   4 RFSKRLGDFSL--DADFTLPGQGVTAIFGRSGSGKTTLIRLIAGLTRPDEGEIVLNGRTLfdsrkgIFLPPEKRRIGYVF 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   82 QAYALFPNMTVAQNVSFGL-RVSGKSRSEIDATVKEMLSLirlDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEP 160
Cdd:TIGR02142  82 QEARLFPHLSVRGNLRYGMkRARPSERRISFERVIELLGI---GHLLGRLPGRLSGGEKQRVAIGRALLSSPRLLLMDEP 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  161 LSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNRPASRFVA-SFVGTLNm 239
Cdd:TIGR02142 159 LAALDDPRKYEILPYLERLHAEFGIPILYVSHSLQEVLRLADRVVVLEDGRVAAAGPIAEVWASPDLPWLArEDQGSLI- 237

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 559158796  240 lEASVSEPAQN----SIDLDGRQITVQETLAhhPKGKPLTLALRPEAVSLEARKSHDTS----LEATI 299
Cdd:TIGR02142 238 -EGVVAEHDQHygltALRLGGGHLWVPENLG--PTGARLRLRVPARDVSLALQKPEATSirniLPARV 302
HisP COG4598
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];
4-232 4.88e-56

ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443652 [Multi-domain]  Cd Length: 259  Bit Score: 183.46  E-value: 4.88e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGkDVVNLRPNQR-------- 75
Cdd:COG4598    9 LEVRDLHKSFGDLEVLKGVSLTARKGDVISIIGSSGSGKSTFLRCINLLETPDSGEIRVGG-EEIRLKPDRDgelvpadr 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  76 --------NIGMVFQAYALFPNMTVAQNVSFG-LRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALAR 146
Cdd:COG4598   88 rqlqrirtRLGMVFQSFNLWSHMTVLENVIEApVHVLGRPKAEAIERAEALLAKVGLADKRDAYPAHLSGGQQQRAAIAR 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 147 ALATKPQVLLLDEPLSALDAKIrisLREEIRAIQQ--KLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNR 224
Cdd:COG4598  168 ALAMEPEVMLFDEPTSALDPEL---VGEVLKVMRDlaEEGRTMLVVTHEMGFARDVSSHVVFLHQGRIEEQGPPAEVFGN 244

                        250
                 ....*....|..
gi 559158796 225 PAS----RFVAS 232
Cdd:COG4598  245 PKSerlrQFLSS 256
FtsE TIGR02673
cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC ...
 6-211 7.25e-56

cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC transporter ATP-binding protein family. This protein, and its permease partner FtsX, localize to the division site. In a number of species, the ftsEX gene pair is located next to FtsY, the signal recognition particle-docking protein. [Cellular processes, Cell division]


Pssm-ID: 131721 [Multi-domain]  Cd Length: 214  Bit Score: 181.68  E-value: 7.25e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796    6 IKNLKKSFGTNT-VVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQ-----RNIGM 79
Cdd:TIGR02673   4 FHNVSKAYPGGVaALHDVSLHIRKGEFLFLTGPSGAGKTTLLKLLYGALTPSRGQVRIAGEDVNRLRGRQlpllrRRIGV 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   80 VFQAYALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDE 159
Cdd:TIGR02673  84 VFQDFRLLPDRTVYENVALPLEVRGKKEREIQRRVGAALRQVGLEHKADAFPEQLSGGEQQRVAIARAIVNSPPLLLADE 163

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 559158796  160 PLSALDAkiriSLREEIRAIQQKL---GITTVFVTHDQEEALSISDRIVVMHEGR 211
Cdd:TIGR02673 164 PTGNLDP----DLSERILDLLKRLnkrGTTVIVATHDLSLVDRVAHRVIILDDGR 214
LptB COG1137
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ...
 1-228 7.46e-56

ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440752 [Multi-domain]  Cd Length: 240  Bit Score: 182.15  E-value: 7.46e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   1 MAFLNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQR---NI 77
Cdd:COG1137    1 MMTLEAENLVKSYGKRTVVKDVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGRIFLDGEDITHLPMHKRarlGI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  78 GMVFQAYALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLL 157
Cdd:COG1137   81 GYLPQEASIFRKLTVEDNILAVLELRKLSKKEREERLEELLEEFGITHLRKSKAYSLSGGERRRVEIARALATNPKFILL 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 559158796 158 DEPLSALDAkirISLrEEIRAIQQKL---GItTVFVT-HDQEEALSISDRIVVMHEGRADQIGSPFDIYNRPASR 228
Cdd:COG1137  161 DEPFAGVDP---IAV-ADIQKIIRHLkerGI-GVLITdHNVRETLGICDRAYIISEGKVLAEGTPEEILNNPLVR 230
FetA COG4619
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
4-211 8.41e-56

ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443661 [Multi-domain]  Cd Length: 209  Bit Score: 181.17  E-value: 8.41e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQ--RNIGMVF 81
Cdd:COG4619    1 LELEGLSFRVGGKPILSPVSLTLEAGECVAITGPSGSGKSTLLRALADLDPPTSGEIYLDGKPLSAMPPPEwrRQVAYVP 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  82 QAYALFPNmTVAQNVSFGLRVSGKSRSEidATVKEMLSLIRLDH-LADRYPYQMSGGQQQRVALARALATKPQVLLLDEP 160
Cdd:COG4619   81 QEPALWGG-TVRDNLPFPFQLRERKFDR--ERALELLERLGLPPdILDKPVERLSGGERQRLALIRALLLQPDVLLLDEP 157

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 559158796 161 LSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGR 211
Cdd:COG4619  158 TSALDPENTRRVEELLREYLAEEGRAVLWVSHDPEQIERVADRVLTLEAGR 208
3a0107s01c2 TIGR00972
phosphate ABC transporter, ATP-binding protein; This model represents the ATP-binding protein ...
 4-234 1.11e-55

phosphate ABC transporter, ATP-binding protein; This model represents the ATP-binding protein of a family of ABC transporters for inorganic phosphate. In the model species Escherichia coli, a constitutive transporter for inorganic phosphate, with low affinity, is also present. The high affinity transporter that includes this polypeptide is induced when extracellular phosphate concentrations are low. The proteins most similar to the members of this family but not included appear to be amino acid transporters. [Transport and binding proteins, Anions]


Pssm-ID: 273372 [Multi-domain]  Cd Length: 247  Bit Score: 182.11  E-value: 1.11e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796    4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLR-------MIAGFETpdNGSIEIDGK-------DVVN 69
Cdd:TIGR00972   2 IEIENLNLFYGEKEALKNINLDIPKNQVTALIGPSGCGKSTLLRslnrmndLVPGVRI--EGKVLFDGQdiydkkiDVVE 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   70 LRpnqRNIGMVFQAYALFPnMTVAQNVSFGLRVSG-KSRSEIDATVKEMLSLIRL-DHLADR---YPYQMSGGQQQRVAL 144
Cdd:TIGR00972  80 LR---RRVGMVFQKPNPFP-MSIYDNIAYGPRLHGiKDKKELDEIVEESLKKAALwDEVKDRlhdSALGLSGGQQQRLCI 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  145 ARALATKPQVLLLDEPLSALDAKIRISLREEIRAIQQKLgiTTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNR 224
Cdd:TIGR00972 156 ARALAVEPEVLLLDEPTSALDPIATGKIEELIQELKKKY--TIVIVTHNMQQAARISDRTAFFYDGELVEYGPTEQIFTN 233

                         250
                  ....*....|
gi 559158796  225 PASRFVASFV 234
Cdd:TIGR00972 234 PKEKRTEDYI 243
tauB PRK11248
taurine ABC transporter ATP-binding subunit;
4-210 5.15e-55

taurine ABC transporter ATP-binding subunit;


Pssm-ID: 183056 [Multi-domain]  Cd Length: 255  Bit Score: 180.67  E-value: 5.15e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNlrPNQRNiGMVFQA 83
Cdd:PRK11248   2 LQISHLYADYGGKPALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSITLDGKPVEG--PGAER-GVVFQN 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  84 YALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSA 163
Cdd:PRK11248  79 EGLLPWRNVQDNVAFGLQLAGVEKMQRLEIAHQMLKKVGLEGAEKRYIWQLSGGQRQRVGIARALAANPQLLLLDEPFGA 158

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 559158796 164 LDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEG 210
Cdd:PRK11248 159 LDAFTREQMQTLLLKLWQETGKQVLLITHDIEEAVFMATELVLLSPG 205
ABC_YhbG cd03218
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ...
 4-228 5.77e-55

ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.


Pssm-ID: 213185 [Multi-domain]  Cd Length: 232  Bit Score: 179.66  E-value: 5.77e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQR---NIGMV 80
Cdd:cd03218    1 LRAENLSKRYGKRKVVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILLDGQDITKLPMHKRarlGIGYL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  81 FQAYALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEP 160
Cdd:cd03218   81 PQEASIFRKLTVEENILAVLEIRGLSKKEREEKLEELLEEFHITHLRKSKASSLSGGERRRVEIARALATNPKFLLLDEP 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 559158796 161 LSALDAkirISLReEIRAIQQKL---GITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNRPASR 228
Cdd:cd03218  161 FAGVDP---IAVQ-DIQKIIKILkdrGIGVLITDHNVRETLSITDRAYIIYEGKVLAEGTPEEIAANELVR 227
ABC_phnC TIGR02315
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of ...
 4-211 2.34e-54

phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of phosphorus-containing organic compound with a stable direct C-P bond rather than a C-O-P linkage. A number of bacterial species have operons, typically about 14 genes in size, with genes for ATP-dependent transport of phosphonates, degradation, and regulation of the expression of the system. Members of this protein family are the ATP-binding cassette component of tripartite ABC transporters of phosphonates. [Transport and binding proteins, Anions]


Pssm-ID: 131368 [Multi-domain]  Cd Length: 243  Bit Score: 178.65  E-value: 2.34e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796    4 LNIKNLKKSFGTNTVV-HDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVN-----LRPNQRNI 77
Cdd:TIGR02315   2 LEVENLSKVYPNGKQAlKNINLNINPGEFVAIIGPSGAGKSTLLRCINRLVEPSSGSILLEGTDITKlrgkkLRKLRRRI 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   78 GMVFQAYALFPNMTVAQNVSFGlRVSGK----------SRSEIdATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARA 147
Cdd:TIGR02315  82 GMIFQHYNLIERLTVLENVLHG-RLGYKptwrsllgrfSEEDK-ERALSALERVGLADKAYQRADQLSGGQQQRVAIARA 159

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 559158796  148 LATKPQVLLLDEPLSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGR 211
Cdd:TIGR02315 160 LAQQPDLILADEPIASLDPKTSKQVMDYLKRINKEDGITVIINLHQVDLAKKYADRIVGLKAGE 223
ABC_PhnC_transporter cd03256
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ...
 4-211 2.96e-54

ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213223 [Multi-domain]  Cd Length: 241  Bit Score: 178.15  E-value: 2.96e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNT-VVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQ-----RNI 77
Cdd:cd03256    1 IEVENLSKTYPNGKkALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIDGTDINKLKGKAlrqlrRQI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  78 GMVFQAYALFPNMTVAQNVSFG-------LRVSGKSRSEID-ATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALA 149
Cdd:cd03256   81 GMIFQQFNLIERLSVLENVLSGrlgrrstWRSLFGLFPKEEkQRALAALERVGLLDKAYQRADQLSGGQQQRVAIARALM 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 559158796 150 TKPQVLLLDEPLSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGR 211
Cdd:cd03256  161 QQPKLILADEPVASLDPASSRQVMDLLKRINREEGITVIVSLHQVDLAREYADRIVGLKDGR 222
ECF_ATPase_1 TIGR04520
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...
 6-224 8.07e-54

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 275313 [Multi-domain]  Cd Length: 268  Bit Score: 178.01  E-value: 8.07e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796    6 IKNLKKSF--GTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVV---NLRPNQRNIGMV 80
Cdd:TIGR04520   3 VENVSFSYpeSEKPALKNVSLSIEKGEFVAIIGHNGSGKSTLAKLLNGLLLPTSGKVTVDGLDTLdeeNLWEIRKKVGMV 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   81 FQayalfpN-------MTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQ 153
Cdd:TIGR04520  83 FQ------NpdnqfvgATVEDDVAFGLENLGVPREEMRKRVDEALKLVGMEDFRDREPHLLSGGQKQRVAIAGVLAMRPD 156

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 559158796  154 VLLLDEPLSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSiSDRIVVMHEGRADQIGSPFDIYNR 224
Cdd:TIGR04520 157 IIILDEATSMLDPKGRKEVLETIRKLNKEEGITVISITHDMEEAVL-ADRVIVMNKGKIVAEGTPREIFSQ 226
L_ocin_972_ABC TIGR03608
putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly ...
 6-205 1.02e-53

putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly wide distribution consists of a polypeptide related to the lactococcin 972 (see TIGR01653) and multiple-membrane-spanning putative immunity protein (see TIGR01654). This model represents a small clade within the ABC transporters that regularly are found adjacent to these bacteriocin system gene pairs and are likely serve as export proteins. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]


Pssm-ID: 188353 [Multi-domain]  Cd Length: 206  Bit Score: 175.88  E-value: 1.02e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796    6 IKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQ-----RN-IGM 79
Cdd:TIGR03608   1 LKNISKKFGDKVILDDLNLTIEKGKMYAIIGESGSGKSTLLNIIGLLEKFDSGQVYLNGQETPPLNSKKaskfrREkLGY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   80 VFQAYALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDE 159
Cdd:TIGR03608  81 LFQNFALIENETVEENLDLGLKYKKLSKKEKREKKKEALEKVGLNLKLKQKIYELSGGEQQRVALARAILKPPPLILADE 160

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 559158796  160 PLSALDAKIrislREEIRAIQQKL---GITTVFVTHDQEEAlSISDRIV 205
Cdd:TIGR03608 161 PTGSLDPKN----RDEVLDLLLELndeGKTIIIVTHDPEVA-KQADRVI 204
thiQ PRK10771
thiamine ABC transporter ATP-binding protein ThiQ;
22-211 2.40e-53

thiamine ABC transporter ATP-binding protein ThiQ;


Pssm-ID: 182716 [Multi-domain]  Cd Length: 232  Bit Score: 175.54  E-value: 2.40e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  22 FNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQRNIGMVFQAYALFPNMTVAQNVSFGLR 101
Cdd:PRK10771  18 FDLTVERGERVAILGPSGAGKSTLLNLIAGFLTPASGSLTLNGQDHTTTPPSRRPVSMLFQENNLFSHLTVAQNIGLGLN 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 102 VSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSALDAKIR---ISLREEIRA 178
Cdd:PRK10771  98 PGLKLNAAQREKLHAIARQMGIEDLLARLPGQLSGGQRQRVALARCLVREQPILLLDEPFSALDPALRqemLTLVSQVCQ 177

                        170       180       190
                 ....*....|....*....|....*....|...
gi 559158796 179 IQQklgITTVFVTHDQEEALSISDRIVVMHEGR 211
Cdd:PRK10771 178 ERQ---LTLLMVSHSLEDAARIAPRSLVVADGR 207
ABC_TM1139_LivF_branched cd03224
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ...
 4-215 4.86e-53

ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.


Pssm-ID: 213191 [Multi-domain]  Cd Length: 222  Bit Score: 174.54  E-value: 4.86e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQRN---IGMV 80
Cdd:cd03224    1 LEVENLNAGYGKSQILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFDGRDITGLPPHERAragIGYV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  81 FQAYALFPNMTVAQNVSFGLRVsgKSRSEIDATVKEMLSLI-RLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDE 159
Cdd:cd03224   81 PEGRRIFPELTVEENLLLGAYA--RRRAKRKARLERVYELFpRLKERRKQLAGTLSGGEQQMLAIARALMSRPKLLLLDE 158

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 559158796 160 PLSALDAKIRISLREEIRAIQQKlGITTVFVTHDQEEALSISDRIVVM------HEGRADQI 215
Cdd:cd03224  159 PSEGLAPKIVEEIFEAIRELRDE-GVTILLVEQNARFALEIADRAYVLergrvvLEGTAAEL 219
ABC_subfamily_A cd03263
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ...
 4-218 6.21e-53

ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.


Pssm-ID: 213230 [Multi-domain]  Cd Length: 220  Bit Score: 174.23  E-value: 6.21e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFG--TNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPN-QRNIGMV 80
Cdd:cd03263    1 LQIRNLTKTYKkgTKPAVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYINGYSIRTDRKAaRQSLGYC 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  81 FQAYALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEP 160
Cdd:cd03263   81 PQFDALFDELTVREHLRFYARLKGLPKSEIKEEVELLLRVLGLTDKANKRARTLSGGMKRKLSLAIALIGGPSVLLLDEP 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 559158796 161 LSALDAKIRISLREEIRAIQQKLGIttVFVTHDQEEALSISDRIVVMHEGRADQIGSP 218
Cdd:cd03263  161 TSGLDPASRRAIWDLILEVRKGRSI--ILTTHSMDEAEALCDRIAIMSDGKLRCIGSP 216
thiQ TIGR01277
thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ...
 22-216 7.16e-53

thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ATPase subunit ThiQ of the ThiBPQ thiamine (and thiamine pyrophosphate) ABC transporter in several Proteobacteria. This protein is found so far only in Proteobacteria, and is found in complete genomes only if the ThiB and ThiP subunits are also found. [Transport and binding proteins, Other]


Pssm-ID: 130344 [Multi-domain]  Cd Length: 213  Bit Score: 173.89  E-value: 7.16e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   22 FNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQRNIGMVFQAYALFPNMTVAQNVSFGLR 101
Cdd:TIGR01277  17 FDLNVADGEIVAIMGPSGAGKSTLLNLIAGFIEPASGSIKVNDQSHTGLAPYQRPVSMLFQENNLFAHLTVRQNIGLGLH 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  102 VSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSALDAKIRISLREEIRAIQQ 181
Cdd:TIGR01277  97 PGLKLNAEQQEKVVDAAQQVGIADYLDRLPEQLSGGQRQRVALARCLVRPNPILLLDEPFSALDPLLREEMLALVKQLCS 176

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 559158796  182 KLGITTVFVTHDQEEALSISDRIVVMHEGRADQIG 216
Cdd:TIGR01277 177 ERQRTLLMVTHHLSDARAIASQIAVVSQGKIKVVS 211
YbbA COG4181
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ...
 4-211 8.94e-53

Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443338 [Multi-domain]  Cd Length: 233  Bit Score: 174.16  E-value: 8.94e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTN----TVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQR---- 75
Cdd:COG4181    9 IELRGLTKTVGTGagelTILKGISLEVEAGESVAIVGASGSGKSTLLGLLAGLDRPTSGTVRLAGQDLFALDEDARarlr 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  76 --NIGMVFQAYALFPNMTVAQNVSFGLRVSGksRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQ 153
Cdd:COG4181   89 arHVGFVFQSFQLLPTLTALENVMLPLELAG--RRDARARARALLERVGLGHRLDHYPAQLSGGEQQRVALARAFATEPA 166

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 559158796 154 VLLLDEPLSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSiSDRIVVMHEGR 211
Cdd:COG4181  167 ILFADEPTGNLDAATGEQIIDLLFELNRERGTTLVLVTHDPALAAR-CDRVLRLRAGR 223
ABC_ThiQ_thiamine_transporter cd03298
ATP-binding cassette domain of the thiamine transport system; Part of the ...
 21-211 1.27e-52

ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213265 [Multi-domain]  Cd Length: 211  Bit Score: 173.06  E-value: 1.27e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  21 DFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQRNIGMVFQAYALFPNMTVAQNVSFGL 100
Cdd:cd03298   16 HFDLTFAQGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLINGVDVTAAPPADRPVSMLFQENNLFAHLTVEQNVGLGL 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 101 RVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSALDAKIRISLREEIRAIQ 180
Cdd:cd03298   96 SPGLKLTAEDRQAIEVALARVGLAGLEKRLPGELSGGERQRVALARVLVRDKPVLLLDEPFAALDPALRAEMLDLVLDLH 175

                        170       180       190
                 ....*....|....*....|....*....|.
gi 559158796 181 QKLGITTVFVTHDQEEALSISDRIVVMHEGR 211
Cdd:cd03298  176 AETKMTVLMVTHQPEDAKRLAQRVVFLDNGR 206
ABC_ATPase cd00267
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ...
 6-211 1.73e-52

ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213179 [Multi-domain]  Cd Length: 157  Bit Score: 170.89  E-value: 1.73e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   6 IKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDV--VNLRPNQRNIGMVFQa 83
Cdd:cd00267    2 IENLSFRYGGRTALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDGKDIakLPLEELRRRIGYVPQ- 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  84 yalfpnmtvaqnvsfglrvsgksrseidatvkemlslirldhladrypyqMSGGQQQRVALARALATKPQVLLLDEPLSA 163
Cdd:cd00267   81 --------------------------------------------------LSGGQRQRVALARALLLNPDLLLLDEPTSG 110

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 559158796 164 LDAKIRISLREEIRAIQQKlGITTVFVTHDQEEALSISDRIVVMHEGR 211
Cdd:cd00267  111 LDPASRERLLELLRELAEE-GRTVIIVTHDPELAELAADRVIVLKDGK 157
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
 19-162 6.82e-52

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 168.98  E-value: 6.82e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   19 VHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVV--NLRPNQRNIGMVFQAYALFPNMTVAQNV 96
Cdd:pfam00005   1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTddERKSLRKEIGYVFQDPQLFPRLTVRENL 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   97 SFGLRVSGKSRSEIDATVKEMLSLIRLDHLADR----YPYQMSGGQQQRVALARALATKPQVLLLDEPLS 162
Cdd:pfam00005  81 RLGLLLKGLSKREKDARAEEALEKLGLGDLADRpvgeRPGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
ABC_NatA_sodium_exporter cd03266
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ...
 4-211 1.29e-51

ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.


Pssm-ID: 213233 [Multi-domain]  Cd Length: 218  Bit Score: 170.63  E-value: 1.29e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNT----VVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVV-NLRPNQRNIG 78
Cdd:cd03266    2 ITADALTKRFRDVKktvqAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATVDGFDVVkEPAEARRRLG 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  79 MVFQAYALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLD 158
Cdd:cd03266   82 FVSDSTGLYDRLTARENLEYFAGLYGLKGDELTARLEELADRLGMEELLDRRVGGFSTGMRQKVAIARALVHDPPVLLLD 161

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 559158796 159 EPLSALDAKIRISLREEIRAiQQKLGITTVFVTHDQEEALSISDRIVVMHEGR 211
Cdd:cd03266  162 EPTTGLDVMATRALREFIRQ-LRALGKCILFSTHIMQEVERLCDRVVVLHRGR 213
ABC_FtsE cd03292
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ...
 7-211 1.42e-51

Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages


Pssm-ID: 213259 [Multi-domain]  Cd Length: 214  Bit Score: 170.67  E-value: 1.42e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   7 KNLKKSFGTNTV-VHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQ-----RNIGMV 80
Cdd:cd03292    4 INVTKTYPNGTAaLDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVNGQDVSDLRGRAipylrRKIGVV 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  81 FQAYALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEP 160
Cdd:cd03292   84 FQDFRLLPDRNVYENVAFALEVTGVPPREIRKRVPAALELVGLSHKHRALPAELSGGEQQRVAIARAIVNSPTILIADEP 163

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 559158796 161 LSALDAKiriSLREEIRAIQQ--KLGITTVFVTHDQEEALSISDRIVVMHEGR 211
Cdd:cd03292  164 TGNLDPD---TTWEIMNLLKKinKAGTTVVVATHAKELVDTTRHRVIALERGK 213
ssuB PRK11247
aliphatic sulfonates transport ATP-binding subunit; Provisional
 4-211 3.58e-51

aliphatic sulfonates transport ATP-binding subunit; Provisional


Pssm-ID: 183055 [Multi-domain]  Cd Length: 257  Bit Score: 171.01  E-value: 3.58e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQRnigMVFQA 83
Cdd:PRK11247  13 LLLNAVSKRYGERTVLNQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLETPSAGELLAGTAPLAEAREDTR---LMFQD 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  84 YALFPNMTVAQNVSFGLRvsGKSRSEidatVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSA 163
Cdd:PRK11247  90 ARLLPWKKVIDNVGLGLK--GQWRDA----ALQALAAVGLADRANEWPAALSGGQKQRVALARALIHRPGLLLLDEPLGA 163

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 559158796 164 LDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGR 211
Cdd:PRK11247 164 LDALTRIEMQDLIESLWQQHGFTVLLVTHDVSEAVAMADRVLLIEEGK 211
PRK11264 PRK11264
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
 1-211 4.81e-51

putative amino-acid ABC transporter ATP-binding protein YecC; Provisional


Pssm-ID: 183063 [Multi-domain]  Cd Length: 250  Bit Score: 170.32  E-value: 4.81e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   1 MAFLNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSI-----EIDGKDVVN-----L 70
Cdd:PRK11264   1 MSAIEVKNLVKKFHGQTVLHGIDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGTIrvgdiTIDTARSLSqqkglI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  71 RPNQRNIGMVFQAYALFPNMTVAQNVSFG-LRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALA 149
Cdd:PRK11264  81 RQLRQHVGFVFQNFNLFPHRTVLENIIEGpVIVKGEPKEEATARARELLAKVGLAGKETSYPRRLSGGQQQRVAIARALA 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 559158796 150 TKPQVLLLDEPLSALDAKIRISLREEIRAIQQKlGITTVFVTHDQEEALSISDRIVVMHEGR 211
Cdd:PRK11264 161 MRPEVILFDEPTSALDPELVGEVLNTIRQLAQE-KRTMVIVTHEMSFARDVADRAIFMDQGR 221
ectoine_ehuA TIGR03005
ectoine/hydroxyectoine ABC transporter, ATP-binding protein; Members of this family are the ...
 4-234 1.08e-50

ectoine/hydroxyectoine ABC transporter, ATP-binding protein; Members of this family are the ATP-binding protein of a conserved four gene ABC transporter operon found next to ectoine unilization operons and ectoine biosynthesis operons. Ectoine is a compatible solute that protects enzymes from high osmolarity. It is released by some species in response to hypoosmotic shock, and it is taken up by a number of bacteria as a compatible solute or for consumption. This family shows strong sequence similiarity to a number of amino acid ABC transporter ATP-binding proteins.


Pssm-ID: 132050 [Multi-domain]  Cd Length: 252  Bit Score: 169.63  E-value: 1.08e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796    4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGK---------------DVV 68
Cdd:TIGR03005   1 VRFSDVTKRFGILTVLDGLNFSVAAGEKVALIGPSGSGKSTILRILMTLEPIDEGQIQVEGEqlyhmpgrngplvpaDEK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   69 NLRPNQRNIGMVFQAYALFPNMTVAQNVSFG-LRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARA 147
Cdd:TIGR03005  81 HLRQMRNKIGMVFQSFNLFPHKTVLDNVTEApVLVLGMARAEAEKRAMELLDMVGLADKADHMPAQLSGGQQQRVAIARA 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  148 LATKPQVLLLDEPLSALDAKirisLREEIRAIQQKLG----ITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYN 223
Cdd:TIGR03005 161 LAMRPKVMLFDEVTSALDPE----LVGEVLNVIRRLAsehdLTMLLVTHEMGFAREFADRVCFFDKGRIVEQGKPDEIFR 236

                         250
                  ....*....|.
gi 559158796  224 RPASRFVASFV 234
Cdd:TIGR03005 237 QPKEERTREFL 247
CcmA COG4133
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ...
 4-197 8.52e-50

ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443308 [Multi-domain]  Cd Length: 206  Bit Score: 165.73  E-value: 8.52e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPN-QRNIGMVFQ 82
Cdd:COG4133    3 LEAENLSCRRGERLLFSGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLWNGEPIRDAREDyRRRLAYLGH 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  83 AYALFPNMTVAQNVSFGLRVSGKSRSeiDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLS 162
Cdd:COG4133   83 ADGLKPELTVRENLRFWAALYGLRAD--REAIDEALEAVGLAGLADLPVRQLSAGQKRRVALARLLLSPAPLWLLDEPFT 160

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 559158796 163 ALDAKIRISLREEIRAiQQKLGITTVFVTHDQEEA 197
Cdd:COG4133  161 ALDAAGVALLAELIAA-HLARGGAVLLTTHQPLEL 194
ZnuC COG1121
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ...
 1-211 9.36e-50

ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440738 [Multi-domain]  Cd Length: 245  Bit Score: 166.80  E-value: 9.36e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   1 MAFLNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRpnqRNIGMV 80
Cdd:COG1121    4 MPAIELENLTVSYGGRPVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRLFGKPPRRAR---RRIGYV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  81 FQAYAL---FPnMTVAQNVSFGL----RVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQ 153
Cdd:COG1121   81 PQRAEVdwdFP-ITVRDVVLMGRygrrGLFRRPSRADREAVDEALERVGLEDLADRPIGELSGGQQQRVLLARALAQDPD 159

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 559158796 154 VLLLDEPLSALDAKIRISLREEIRAIQQKlGITTVFVTHDQEEALSISDRIVVMHEGR 211
Cdd:COG1121  160 LLLLDEPFAGVDAATEEALYELLRELRRE-GKTILVVTHDLGAVREYFDRVLLLNRGL 216
PhnK COG1101
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 4-211 1.16e-49

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 440718 [Multi-domain]  Cd Length: 264  Bit Score: 167.18  E-value: 1.16e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSF--GT---NTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQR--N 76
Cdd:COG1101    2 LELKNLSKTFnpGTvneKRALDGLNLTIEEGDFVTVIGSNGAGKSTLLNAIAGSLPPDSGSILIDGKDVTKLPEYKRakY 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  77 IGMVFQAYAL--FPNMTVAQNVS--------FGLRvSGKSRSEIDAtVKEMLSLIRLDhLADRYPYQM---SGGQQQRVA 143
Cdd:COG1101   82 IGRVFQDPMMgtAPSMTIEENLAlayrrgkrRGLR-RGLTKKRREL-FRELLATLGLG-LENRLDTKVgllSGGQRQALS 158

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 559158796 144 LARALATKPQVLLLDEPLSALD---AKIRISLREEIraIQQKlGITTVFVTHDQEEALSISDRIVVMHEGR 211
Cdd:COG1101  159 LLMATLTKPKLLLLDEHTAALDpktAALVLELTEKI--VEEN-NLTTLMVTHNMEQALDYGNRLIMMHEGR 226
ABC_DrrA cd03265
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ...
 6-218 1.44e-49

Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213232 [Multi-domain]  Cd Length: 220  Bit Score: 165.62  E-value: 1.44e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   6 IKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVV-NLRPNQRNIGMVFQAY 84
Cdd:cd03265    3 VENLVKKYGDFEAVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRATVAGHDVVrEPREVRRRIGIVFQDL 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  85 ALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSAL 164
Cdd:cd03265   83 SVDDELTGWENLYIHARLYGVPGAERRERIDELLDFVGLLEAADRLVKTYSGGMRRRLEIARSLVHRPEVLFLDEPTIGL 162

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 559158796 165 DAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSP 218
Cdd:cd03265  163 DPQTRAHVWEYIEKLKEEFGMTILLTTHYMEEAEQLCDRVAIIDHGRIIAEGTP 216
ABC_BcrA_bacitracin_resist cd03268
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ...
 4-211 1.74e-49

ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.


Pssm-ID: 213235 [Multi-domain]  Cd Length: 208  Bit Score: 164.70  E-value: 1.74e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQRNIGMVFQA 83
Cdd:cd03268    1 LKTNDLTKTYGKKRVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEITFDGKSYQKNIEALRRIGALIEA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  84 YALFPNMTVAQNVSFGLRVSGKSRSEIDatvkEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSA 163
Cdd:cd03268   81 PGFYPNLTARENLRLLARLLGIRKKRID----EVLDVVGLKDSAKKKVKGFSLGMKQRLGIALALLGNPDLLILDEPTNG 156

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 559158796 164 LDAKIRISLREEIRAIQQKlGITTVFVTHDQEEALSISDRIVVMHEGR 211
Cdd:cd03268  157 LDPDGIKELRELILSLRDQ-GITVLISSHLLSEIQKVADRIGIINKGK 203
cbiO PRK13637
energy-coupling factor transporter ATPase;
21-223 2.46e-49

energy-coupling factor transporter ATPase;


Pssm-ID: 237455 [Multi-domain]  Cd Length: 287  Bit Score: 167.15  E-value: 2.46e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  21 DFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDV----VNLRPNQRNIGMVFQ--AYALFPNmTVAQ 94
Cdd:PRK13637  25 NVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIIIDGVDItdkkVKLSDIRKKVGLVFQypEYQLFEE-TIEK 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  95 NVSFGLRVSGKSRSEIDATVKEMLSLIRLDH--LADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSALDAKIRISL 172
Cdd:PRK13637 104 DIAFGPINLGLSEEEIENRVKRAMNIVGLDYedYKDKSPFELSGGQKRRVAIAGVVAMEPKILILDEPTAGLDPKGRDEI 183

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 559158796 173 REEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYN 223
Cdd:PRK13637 184 LNKIKELHKEYNMTIILVSHSMEDVAKLADRIIVMNKGKCELQGTPREVFK 234
LivF COG0410
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ...
 1-211 4.03e-49

ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];


Pssm-ID: 440179 [Multi-domain]  Cd Length: 236  Bit Score: 164.77  E-value: 4.03e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   1 MAFLNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQRN---I 77
Cdd:COG0410    1 MPMLEVENLHAGYGGIHVLHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPRSGSIRFDGEDITGLPPHRIArlgI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  78 GMVFQAYALFPNMTVAQNVSFGLRVsGKSRSEIDATVKEMLSLI-----RLDHLADrypyQMSGGQQQRVALARALATKP 152
Cdd:COG0410   81 GYVPEGRRIFPSLTVEENLLLGAYA-RRDRAEVRADLERVYELFprlkeRRRQRAG----TLSGGEQQMLAIGRALMSRP 155

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 559158796 153 QVLLLDEPLSALDAKIRISLREEIRAIQQKlGITTVFVTHDQEEALSISDRIVVMHEGR 211
Cdd:COG0410  156 KLLLLDEPSLGLAPLIVEEIFEIIRRLNRE-GVTILLVEQNARFALEIADRAYVLERGR 213
PRK10070 PRK10070
proline/glycine betaine ABC transporter ATP-binding protein ProV;
14-233 9.91e-49

proline/glycine betaine ABC transporter ATP-binding protein ProV;


Pssm-ID: 182221 [Multi-domain]  Cd Length: 400  Bit Score: 168.67  E-value: 9.91e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  14 GTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRP------NQRNIGMVFQAYALF 87
Cdd:PRK10070  39 GLSLGVKDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGVDIAKISDaelrevRRKKIAMVFQSFALM 118

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  88 PNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSALDAK 167
Cdd:PRK10070 119 PHMTVLDNTAFGMELAGINAEERREKALDALRQVGLENYAHSYPDELSGGMRQRVGLARALAINPDILLMDEAFSALDPL 198

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 559158796 168 IRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNRPASRFVASF 233
Cdd:PRK10070 199 IRTEMQDELVKLQAKHQRTIVFISHDLDEAMRIGDRIAIMQNGEVVQVGTPDEILNNPANDYVRTF 264
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
 4-225 3.10e-48

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 170.25  E-value: 3.10e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSF-----------GTNTVVHDFNLAVGKGEFVSFLGPSGCGKTT----VLRMIagfetPDNGSIEIDGKDVV 68
Cdd:COG4172  276 LEARDLKVWFpikrglfrrtvGHVKAVDGVSLTLRRGETLGLVGESGSGKSTlglaLLRLI-----PSEGEIRFDGQDLD 350

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  69 NL-----RPNQRNIGMVFQ-AYA-LFPNMTVAQNVSFGLRV--SGKSRSEIDATVKEMLSLIRLDH-LADRYPYQMSGGQ 138
Cdd:COG4172  351 GLsrralRPLRRRMQVVFQdPFGsLSPRMTVGQIIAEGLRVhgPGLSAAERRARVAEALEEVGLDPaARHRYPHEFSGGQ 430

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 139 QQRVALARALATKPQVLLLDEPLSALDAKIRISLREEIRAIQQKLGITTVFVTHDqeeaLS----ISDRIVVMHEGRADQ 214
Cdd:COG4172  431 RQRIAIARALILEPKLLVLDEPTSALDVSVQAQILDLLRDLQREHGLAYLFISHD----LAvvraLAHRVMVMKDGKVVE 506

                        250
                 ....*....|.
gi 559158796 215 IGSPFDIYNRP 225
Cdd:COG4172  507 QGPTEQVFDAP 517
ABC_Metallic_Cations cd03235
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ...
 6-207 6.31e-48

ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.


Pssm-ID: 213202 [Multi-domain]  Cd Length: 213  Bit Score: 160.78  E-value: 6.31e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   6 IKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRpnqRNIGMVFQAYA 85
Cdd:cd03235    2 VEDLTVSYGGHPVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRVFGKPLEKER---KRIGYVPQRRS 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  86 L---FPnMTVAQNVSFGL--------RVSGKSRSEIDatvkEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQV 154
Cdd:cd03235   79 IdrdFP-ISVRDVVLMGLyghkglfrRLSKADKAKVD----EALERVGLSELADRQIGELSGGQQQRVLLARALVQDPDL 153

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 559158796 155 LLLDEPLSALDAKIRISLREEIRAIQQKlGITTVFVTHDQEEALSISDRIVVM 207
Cdd:cd03235  154 LLLDEPFAGVDPKTQEDIYELLRELRRE-GMTILVVTHDLGLVLEYFDRVLLL 205
nickel_nikE TIGR02769
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a ...
 4-234 2.77e-47

nickel import ATP-binding protein NikE; This family represents the NikE subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 131816 [Multi-domain]  Cd Length: 265  Bit Score: 161.13  E-value: 2.77e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796    4 LNIKNLKKSFGTN---------TVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQ 74
Cdd:TIGR02769   3 LEVRDVTHTYRTGglfgakqraPVLTNVSLSIEEGETVGLLGRSGCGKSTLARLLLGLEKPAQGTVSFRGQDLYQLDRKQ 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   75 -----RNIGMVFQ-AYALF-PNMTVAQNVSFGLR-VSGKSRSEIDATVKEMLSLIRL-DHLADRYPYQMSGGQQQRVALA 145
Cdd:TIGR02769  83 rrafrRDVQLVFQdSPSAVnPRMTVRQIIGEPLRhLTSLDESEQKARIAELLDMVGLrSEDADKLPRQLSGGQLQRINIA 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  146 RALATKPQVLLLDEPLSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGR--ADQIGSPFDIYN 223
Cdd:TIGR02769 163 RALAVKPKLIVLDEAVSNLDMVLQAVILELLRKLQQAFGTAYLFITHDLRLVQSFCQRVAVMDKGQivEECDVAQLLSFK 242

                         250
                  ....*....|.
gi 559158796  224 RPASRFVASFV 234
Cdd:TIGR02769 243 HPAGRNLQSAV 253
SunT COG2274
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ...
 18-218 4.52e-47

ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];


Pssm-ID: 441875 [Multi-domain]  Cd Length: 711  Bit Score: 169.63  E-value: 4.52e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  18 VVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQ--RNIGMVFQAYALFpNMTVAQN 95
Cdd:COG2274  490 VLDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEPTSGRILIDGIDLRQIDPASlrRQIGVVLQDVFLF-SGTIREN 568

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  96 VSFGlrvsgksRSEI-DATVKEMLSLIRLDHLADRYP--YQM---------SGGQQQRVALARALATKPQVLLLDEPLSA 163
Cdd:COG2274  569 ITLG-------DPDAtDEEIIEAARLAGLHDFIEALPmgYDTvvgeggsnlSGGQRQRLAIARALLRNPRILILDEATSA 641

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 559158796 164 LDAKIRISLREEIRAIQQklGITTVFVTHDqEEALSISDRIVVMHEGRADQIGSP 218
Cdd:COG2274  642 LDAETEAIILENLRRLLK--GRTVIIIAHR-LSTIRLADRIIVLDKGRIVEDGTH 693
nikE PRK10419
nickel ABC transporter ATP-binding protein NikE;
1-228 1.02e-46

nickel ABC transporter ATP-binding protein NikE;


Pssm-ID: 236689 [Multi-domain]  Cd Length: 268  Bit Score: 159.47  E-value: 1.02e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   1 MAFLNIKNLKKSFGTN---------TVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNL- 70
Cdd:PRK10419   1 MTLLNVSGLSHHYAHGglsgkhqhqTVLNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVSWRGEPLAKLn 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  71 ----RPNQRNIGMVFQ--AYALFPNMTVAQNVSFGLR-VSGKSRSEIDATVKEMLSLIRLD-HLADRYPYQMSGGQQQRV 142
Cdd:PRK10419  81 raqrKAFRRDIQMVFQdsISAVNPRKTVREIIREPLRhLLSLDKAERLARASEMLRAVDLDdSVLDKRPPQLSGGQLQRV 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 143 ALARALATKPQVLLLDEPLSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGR--ADQIGSPFD 220
Cdd:PRK10419 161 CLARALAVEPKLLILDEAVSNLDLVLQAGVIRLLKKLQQQFGTACLFITHDLRLVERFCQRVMVMDNGQivETQPVGDKL 240


                 ....*...
gi 559158796 221 IYNRPASR 228
Cdd:PRK10419 241 TFSSPAGR 248
cbiO PRK13650
energy-coupling factor transporter ATPase;
1-263 1.72e-46

energy-coupling factor transporter ATPase;


Pssm-ID: 184209 [Multi-domain]  Cd Length: 279  Bit Score: 159.51  E-value: 1.72e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   1 MAFLNIKNLKKSFGTNT---VVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDG-----KDVVNLRp 72
Cdd:PRK13650   2 SNIIEVKNLTFKYKEDQekyTLNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIIDGdllteENVWDIR- 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  73 nqRNIGMVFQ-AYALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATK 151
Cdd:PRK13650  81 --HKIGMVFQnPDNQFVGATVEDDVAFGLENKGIPHEEMKERVNEALELVGMQDFKEREPARLSGGQKQRVAIAGAVAMR 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 152 PQVLLLDEPLSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEaLSISDRIVVMHEGRADQIGSPFDIYNRPAS---- 227
Cdd:PRK13650 159 PKIIILDEATSMLDPEGRLELIKTIKGIRDDYQMTVISITHDLDE-VALSDRVLVMKNGQVESTSTPRELFSRGNDllql 237

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 559158796 228 ----RFVASFVGTLNmleasvsepaQNSIDLDGRQITVQE 263
Cdd:PRK13650 238 gldiPFTTSLVQSLR----------QNGYDLPEGYLTEKE 267
ABCC_MRP_Like cd03228
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ...
 4-211 1.89e-46

ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213195 [Multi-domain]  Cd Length: 171  Bit Score: 155.62  E-value: 1.89e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNT--VVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDV--VNLRPNQRNIGM 79
Cdd:cd03228    1 IEFKNVSFSYPGRPkpVLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILIDGVDLrdLDLESLRKNIAY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  80 VFQAYALFpNMTVAQNVsfglrvsgksrseidatvkemlslirldhladrypyqMSGGQQQRVALARALATKPQVLLLDE 159
Cdd:cd03228   81 VPQDPFLF-SGTIRENI-------------------------------------LSGGQRQRIAIARALLRDPPILILDE 122

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 559158796 160 PLSALDAKIRISLREEIRAIQQklGITTVFVTHDqEEALSISDRIVVMHEGR 211
Cdd:cd03228  123 ATSALDPETEALILEALRALAK--GKTVIVIAHR-LSTIRDADRIIVLDDGR 171
cbiO PRK13635
energy-coupling factor ABC transporter ATP-binding protein;
19-222 3.20e-46

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184195 [Multi-domain]  Cd Length: 279  Bit Score: 158.64  E-value: 3.20e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  19 VHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDG-----KDVVNLRpnqRNIGMVFQ-AYALFPNMTV 92
Cdd:PRK13635  23 LKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTITVGGmvlseETVWDVR---RQVGMVFQnPDNQFVGATV 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  93 AQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSALDAKIRISL 172
Cdd:PRK13635 100 QDDVAFGLENIGVPREEMVERVDQALRQVGMEDFLNREPHRLSGGQKQRVAIAGVLALQPDIIILDEATSMLDPRGRREV 179

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 559158796 173 REEIRAIQQKLGITTVFVTHDQEEALSiSDRIVVMHEGRADQIGSPFDIY 222
Cdd:PRK13635 180 LETVRQLKEQKGITVLSITHDLDEAAQ-ADRVIVMNKGEILEEGTPEEIF 228
LPS_export_lptB TIGR04406
LPS export ABC transporter ATP-binding protein; Members of this fmaily are LptB, the ...
 4-230 1.26e-45

LPS export ABC transporter ATP-binding protein; Members of this fmaily are LptB, the ATP-binding cassette protein of an ABC transporter involved in lipopolysaccharide export. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]


Pssm-ID: 275199 [Multi-domain]  Cd Length: 239  Bit Score: 155.90  E-value: 1.26e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796    4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNL---RPNQRNIGMV 80
Cdd:TIGR04406   2 LVAENLIKSYKKRKVVNDVSLSVKSGEIVGLLGPNGAGKTTSFYMIVGLVRPDAGKILIDGQDITHLpmhERARLGIGYL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   81 FQAYALFPNMTVAQNVSFGLRVSGK-SRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDE 159
Cdd:TIGR04406  82 PQEASIFRKLTVEENIMAVLEIRKDlDRAEREERLEALLEEFQISHLRDNKAMSLSGGERRRVEIARALATNPKFILLDE 161

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 559158796  160 PLSALDAKIRISLREEIRAIQQKlGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNRPASRFV 230
Cdd:TIGR04406 162 PFAGVDPIAVGDIKKIIKHLKER-GIGVLITDHNVRETLDICDRAYIISDGKVLAEGTPAEIVANEKVRRV 231
LolD_lipo_ex TIGR02211
lipoprotein releasing system, ATP-binding protein; This model represents LolD, a member of the ...
 4-211 4.98e-45

lipoprotein releasing system, ATP-binding protein; This model represents LolD, a member of the ABC transporter family (pfam00005). LolD is involved in localization of lipoproteins in some bacteria. It works with a transmembrane protein LolC, which in some species is a paralogous pair LolC and LolE. Depending on whether the residue immediately following the new, modified N-terminal Cys residue, the nascent lipoprotein may be carried further by LolA and LolB to the outer membrane, or remain at the inner membrane. The top scoring proteins excluded by this model include homologs from the archaeal genus Methanosarcina. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 131266 [Multi-domain]  Cd Length: 221  Bit Score: 153.66  E-value: 4.98e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796    4 LNIKNLKKSFGTN----TVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQR---- 75
Cdd:TIGR02211   2 LKCENLGKRYQEGkldtRVLKGVSLSIGKGEIVAIVGSSGSGKSTLLHLLGGLDNPTSGEVLFNGQSLSKLSSNERaklr 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   76 --NIGMVFQAYALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQ 153
Cdd:TIGR02211  82 nkKLGFIYQFHHLLPDFTALENVAMPLLIGKKSVKEAKERAYEMLEKVGLEHRINHRPSELSGGERQRVAIARALVNQPS 161

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 559158796  154 VLLLDEPLSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSIsDRIVVMHEGR 211
Cdd:TIGR02211 162 LVLADEPTGNLDNNNAKIIFDLMLELNRELNTSFLVVTHDLELAKKL-DRVLEMKDGQ 218
cbiO PRK13634
cobalt transporter ATP-binding subunit; Provisional
 21-226 1.52e-44

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237454 [Multi-domain]  Cd Length: 290  Bit Score: 154.79  E-value: 1.52e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  21 DFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEI------DGKDVVNLRPNQRNIGMVFQayalFPNM---- 90
Cdd:PRK13634  25 DVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVTIgervitAGKKNKKLKPLRKKVGIVFQ----FPEHqlfe 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  91 -TVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDH-LADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSALDAKI 168
Cdd:PRK13634 101 eTVEKDICFGPMNFGVSEEDAKQKAREMIELVGLPEeLLARSPFELSGGQMRRVAIAGVLAMEPEVLVLDEPTAGLDPKG 180

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 559158796 169 RISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNRPA 226
Cdd:PRK13634 181 RKEMMEMFYKLHKEKGLTTVLVTHSMEDAARYADQIVVMHKGTVFLQGTPREIFADPD 238
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
1-289 3.09e-44

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 158.64  E-value: 3.09e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   1 MAFLNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQ---RNI 77
Cdd:COG1129    2 EPLLEMRGISKSFGGVKALDGVSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDSGEILLDGEPVRFRSPRDaqaAGI 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  78 GMVFQAYALFPNMTVAQNVSFGLRVSGK---SRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQV 154
Cdd:COG1129   82 AIIHQELNLVPNLSVAENIFLGREPRRGgliDWRAMRRRARELLARLGLDIDPDTPVGDLSVAQQQLVEIARALSRDARV 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 155 LLLDEPLSALDAKIRISLREEIRAIQQKlGITTVFVTHDQEEALSISDRIVVMHEGRadqigspfdiynrpasrfvasFV 234
Cdd:COG1129  162 LILDEPTASLTEREVERLFRIIRRLKAQ-GVAIIYISHRLDEVFEIADRVTVLRDGR---------------------LV 219

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 559158796 235 GTLNMLEASVSEPAQNSIdldGRQITVQETLAHHPKGKP------LTLALRPEAVSLEARK 289
Cdd:COG1129  220 GTGPVAELTEDELVRLMV---GRELEDLFPKRAAAPGEVvlevegLSVGGVVRDVSFSVRA 277
COG4559 COG4559
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];
4-218 1.29e-43

ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443620 [Multi-domain]  Cd Length: 258  Bit Score: 151.04  E-value: 1.29e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQ--RNIGMVF 81
Cdd:COG4559    2 LEAENLSVRLGGRTLLDDVSLTLRPGELTAIIGPNGAGKSTLLKLLTGELTPSSGEVRLNGRPLAAWSPWElaRRRAVLP 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  82 QAYAL-FPnMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADR-YPyQMSGGQQQRVALARALA-------TKP 152
Cdd:COG4559   82 QHSSLaFP-FTVEEVVALGRAPHGSSAAQDRQIVREALALVGLAHLAGRsYQ-TLSGGEQQRVQLARVLAqlwepvdGGP 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 559158796 153 QVLLLDEPLSALD-----AKIRIsLREEIRAiqqklGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSP 218
Cdd:COG4559  160 RWLFLDEPTSALDlahqhAVLRL-ARQLARR-----GGGVVAVLHDLNLAAQYADRILLLHQGRLVAQGTP 224
PRK10619 PRK10619
histidine ABC transporter ATP-binding protein HisP;
4-234 1.76e-43

histidine ABC transporter ATP-binding protein HisP;


Pssm-ID: 182592 [Multi-domain]  Cd Length: 257  Bit Score: 150.89  E-value: 1.76e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPN---------- 73
Cdd:PRK10619   6 LNVIDLHKRYGEHEVLKGVSLQANAGDVISIIGSSGSGKSTFLRCINFLEKPSEGSIVVNGQTINLVRDKdgqlkvadkn 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  74 -----QRNIGMVFQAYALFPNMTVAQNV-SFGLRVSGKSRSEIDATVKEMLSLIRLDHLA-DRYPYQMSGGQQQRVALAR 146
Cdd:PRK10619  86 qlrllRTRLTMVFQHFNLWSHMTVLENVmEAPIQVLGLSKQEARERAVKYLAKVGIDERAqGKYPVHLSGGQQQRVSIAR 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 147 ALATKPQVLLLDEPLSALDAKirisLREEIRAIQQKL---GITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYN 223
Cdd:PRK10619 166 ALAMEPEVLLFDEPTSALDPE----LVGEVLRIMQQLaeeGKTMVVVTHEMGFARHVSSHVIFLHQGKIEEEGAPEQLFG 241

                        250
                 ....*....|.
gi 559158796 224 RPASRFVASFV 234
Cdd:PRK10619 242 NPQSPRLQQFL 252
YhaQ COG4152
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 4-262 1.80e-43

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443322 [Multi-domain]  Cd Length: 298  Bit Score: 151.80  E-value: 1.80e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVnlRPNQRNIGmvfqa 83
Cdd:COG4152    2 LELKGLTKRFGDKTAVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGEVLWDGEPLD--PEDRRRIG----- 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  84 Y-----ALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLD 158
Cdd:COG4152   75 YlpeerGLYPKMKVGEQLVYLARLKGLSKAEAKRRADEWLERLGLGDRANKKVEELSKGNQQKVQLIAALLHDPELLILD 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 159 EPLSALD---AKIrisLREEIRAIQQKlGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNRPASRFVasFVG 235
Cdd:COG4152  155 EPFSGLDpvnVEL---LKDVIRELAAK-GTTVIFSSHQMELVEELCDRIVIINKGRKVLSGSVDEIRRQFGRNTL--RLE 228

                        250       260
                 ....*....|....*....|....*..
gi 559158796 236 TLNMLEASVSEPAQNSIDLDGRQITVQ 262
Cdd:COG4152  229 ADGDAGWLRALPGVTVVEEDGDGAELK 255
MdlB COG1132
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
14-218 4.08e-43

ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];


Pssm-ID: 440747 [Multi-domain]  Cd Length: 579  Bit Score: 156.86  E-value: 4.08e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  14 GTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQ--RNIGMVFQAYALFpNMT 91
Cdd:COG1132  351 GDRPVLKDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDPTSGRILIDGVDIRDLTLESlrRQIGVVPQDTFLF-SGT 429

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  92 VAQNVSFGlrvsgksRSEI-DATVKEMLSLIRLDHLADRYP--YQ---------MSGGQQQRVALARALATKPQVLLLDE 159
Cdd:COG1132  430 IRENIRYG-------RPDAtDEEVEEAAKAAQAHEFIEALPdgYDtvvgergvnLSGGQRQRIAIARALLKDPPILILDE 502

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 559158796 160 PLSALD----AKIRISLREEIRaiqqklGITTVFVTHDqeeaLS---ISDRIVVMHEGRADQIGSP 218
Cdd:COG1132  503 ATSALDteteALIQEALERLMK------GRTTIVIAHR----LStirNADRILVLDDGRIVEQGTH 558
modC PRK11144
molybdenum ABC transporter ATP-binding protein ModC;
36-302 4.72e-43

molybdenum ABC transporter ATP-binding protein ModC;


Pssm-ID: 182993 [Multi-domain]  Cd Length: 352  Bit Score: 152.34  E-value: 4.72e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  36 GPSGCGKTTVLRMIAGFETPDNGSIEIDGK---DV---VNLRPNQRNIGMVFQAYALFPNMTVAQNVSFGlrVSGKSRSE 109
Cdd:PRK11144  31 GRSGAGKTSLINAISGLTRPQKGRIVLNGRvlfDAekgICLPPEKRRIGYVFQDARLFPHYKVRGNLRYG--MAKSMVAQ 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 110 IDATVkemlSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSALDAKIRISLREEIRAIQQKLGITTVF 189
Cdd:PRK11144 109 FDKIV----ALLGIEPLLDRYPGSLSGGEKQRVAIGRALLTAPELLLMDEPLASLDLPRKRELLPYLERLAREINIPILY 184

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 190 VTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNRPASRFVASFVGTLNMLEASVSEP----AQNSIDLDGRQITVQETL 265
Cdd:PRK11144 185 VSHSLDEILRLADRVVVLEQGKVKAFGPLEEVWASSAMRPWLPKEEQSSILKVTVLEHhphyAMTALALGDQHLWVNKLD 264

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|.
gi 559158796 266 AhhPKGKPLTLALRPEAVSLEARKSHDTS----LEATIDDV 302
Cdd:PRK11144 265 A--PLGTALRIRIQASDVSLVLQPPQQSSirniLRAKVVEI 303
hmuV PRK13548
hemin importer ATP-binding subunit; Provisional
 2-220 1.25e-42

hemin importer ATP-binding subunit; Provisional


Pssm-ID: 237422 [Multi-domain]  Cd Length: 258  Bit Score: 148.77  E-value: 1.25e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   2 AFLNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQ--RNIGM 79
Cdd:PRK13548   1 AMLEARNLSVRLGGRTLLDDVSLTLRPGEVVAILGPNGAGKSTLLRALSGELSPDSGEVRLNGRPLADWSPAElaRRRAV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  80 VFQAYAL-FPnMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADR-YPyQMSGGQQQRVALARALA------TK 151
Cdd:PRK13548  81 LPQHSSLsFP-FTVEEVVAMGRAPHGLSRAEDDALVAAALAQVDLAHLAGRdYP-QLSGGEQQRVQLARVLAqlwepdGP 158

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 559158796 152 PQVLLLDEPLSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFD 220
Cdd:PRK13548 159 PRWLLLDEPTSALDLAHQHHVLRLARQLAHERGLAVIVVLHDLNLAARYADRIVLLHQGRLVADGTPAE 227
ABC_drug_resistance_like cd03264
ABC-type multidrug transport system, ATPase component; The biological function of this family ...
 4-211 1.85e-42

ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213231 [Multi-domain]  Cd Length: 211  Bit Score: 146.57  E-value: 1.85e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVsFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPN-QRNIGMVFQ 82
Cdd:cd03264    1 LQLENLTKRYGKKRALDGVSLTLGPGMYG-LLGPNGAGKTTLMRILATLTPPSSGTIRIDGQDVLKQPQKlRRRIGYLPQ 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  83 AYALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLS 162
Cdd:cd03264   80 EFGVYPNFTVREFLDYIAWLKGIPSKEVKARVDEVLELVNLGDRAKKKIGSLSGGMRRRVGIAQALVGDPSILIVDEPTA 159

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 559158796 163 ALDAKIRISLREEIraiqQKLGITTVFV--THDQEEALSISDRIVVMHEGR 211
Cdd:cd03264  160 GLDPEERIRFRNLL----SELGEDRIVIlsTHIVEDVESLCNQVAVLNKGK 206
SapF COG4167
ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms];
1-225 3.80e-42

ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms];


Pssm-ID: 443328 [Multi-domain]  Cd Length: 265  Bit Score: 147.68  E-value: 3.80e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   1 MAFLNIKNLKKSFGTNT---------VVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVV--N 69
Cdd:COG4167    2 SALLEVRNLSKTFKYRTglfrrqqfeAVKPVSFTLEAGQTLAIIGENGSGKSTLAKMLAGIIEPTSGEILINGHKLEygD 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  70 LRPNQRNIGMVFQ--AYALFPNMTVAQNVSFGLRVSGK-SRSEIDATVKEMLSLIRL--DHlADRYPYQMSGGQQQRVAL 144
Cdd:COG4167   82 YKYRCKHIRMIFQdpNTSLNPRLNIGQILEEPLRLNTDlTAEEREERIFATLRLVGLlpEH-ANFYPHMLSSGQKQRVAL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 145 ARALATKPQVLLLDEPLSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNR 224
Cdd:COG4167  161 ARALILQPKIIIADEALAALDMSVRSQIINLMLELQEKLGISYIYVSQHLGIVKHISDKVLVMHQGEVVEYGKTAEVFAN 240


                 .
gi 559158796 225 P 225
Cdd:COG4167  241 P 241
ABC_putative_ATPase cd03269
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ...
 4-212 4.35e-42

ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213236 [Multi-domain]  Cd Length: 210  Bit Score: 145.89  E-value: 4.35e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLrpNQRNIGMVFQA 83
Cdd:cd03269    1 LEVENVTKRFGRVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFDGKPLDIA--ARNRIGYLPEE 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  84 YALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSA 163
Cdd:cd03269   79 RGLYPKMKVIDQLVYLAQLKGLKKEEARRRIDEWLERLELSEYANKRVEELSKGNQQKVQFIAAVIHDPELLILDEPFSG 158

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 559158796 164 LDAKIRISLREEIRAIQQKlGITTVFVTHDQEEALSISDRIVVMHEGRA 212
Cdd:cd03269  159 LDPVNVELLKDVIRELARA-GKTVILSTHQMELVEELCDRVLLLNKGRA 206
CeuD COG4604
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ...
 6-221 9.02e-42

ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443654 [Multi-domain]  Cd Length: 252  Bit Score: 146.00  E-value: 9.02e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   6 IKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQ--RNIGMVFQA 83
Cdd:COG4604    4 IKNVSKRYGGKVVLDDVSLTIPKGGITALIGPNGAGKSTLLSMISRLLPPDSGEVLVDGLDVATTPSRElaKRLAILRQE 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  84 YALFPNMTVAQNVSFGlRV---SGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEP 160
Cdd:COG4604   84 NHINSRLTVRELVAFG-RFpysKGRLTAEDREIIDEAIAYLDLEDLADRYLDELSGGQRQRAFIAMVLAQDTDYVLLDEP 162

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 559158796 161 LSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDI 221
Cdd:COG4604  163 LNNLDMKHSVQMMKLLRRLADELGKTVVIVLHDINFASCYADHIVAMKDGRVVAQGTPEEI 223
ModF COG1119
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ...
 1-211 1.15e-41

ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];


Pssm-ID: 440736 [Multi-domain]  Cd Length: 250  Bit Score: 146.00  E-value: 1.15e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   1 MAFLNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETP-DNGSIEIDGK-----DVVNLRpnq 74
Cdd:COG1119    1 DPLLELRNVTVRRGGKTILDDISWTVKPGEHWAILGPNGAGKSTLLSLITGDLPPtYGNDVRLFGErrggeDVWELR--- 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  75 RNIGMV--FQAYALFPNMTVAQNV------SFGL--RVSgksrSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVAL 144
Cdd:COG1119   78 KRIGLVspALQLRFPRDETVLDVVlsgffdSIGLyrEPT----DEQRERARELLELLGLAHLADRPFGTLSQGEQRRVLI 153

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 559158796 145 ARALATKPQVLLLDEPLSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGR 211
Cdd:COG1119  154 ARALVKDPELLILDEPTAGLDLGARELLLALLDKLAAEGAPTLVLVTHHVEEIPPGITHVLLLKDGR 220
ABC_Carb_Monos_I cd03216
First domain of the ATP-binding cassette component of monosaccharide transport system; This ...
 4-211 1.34e-41

First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213183 [Multi-domain]  Cd Length: 163  Bit Score: 142.95  E-value: 1.34e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPN---QRNIGMV 80
Cdd:cd03216    1 LELRGITKRFGGVKALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEILVDGKEVSFASPRdarRAGIAMV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  81 fqayalfpnmtvaqnvsfglrvsgksrseidatvkemlslirldhladrypYQMSGGQQQRVALARALATKPQVLLLDEP 160
Cdd:cd03216   81 ---------------------------------------------------YQLSVGERQMVEIARALARNARLLILDEP 109

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 559158796 161 LSALDAKIRISLREEIRAIQQKlGITTVFVTHDQEEALSISDRIVVMHEGR 211
Cdd:cd03216  110 TAALTPAEVERLFKVIRRLRAQ-GVAVIFISHRLDEVFEIADRVTVLRDGR 159
CydD COG4988
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ...
 14-218 2.49e-41

ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444012 [Multi-domain]  Cd Length: 563  Bit Score: 151.83  E-value: 2.49e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  14 GTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPN--QRNIGMVFQAYALFPnMT 91
Cdd:COG4988  348 GGRPALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPYSGSILINGVDLSDLDPAswRRQIAWVPQNPYLFA-GT 426

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  92 VAQNVSFGlrvsgksrsEIDATVKEMLSLIR---LDHLADRYP-----------YQMSGGQQQRVALARALATKPQVLLL 157
Cdd:COG4988  427 IRENLRLG---------RPDASDEELEAALEaagLDEFVAALPdgldtplgeggRGLSGGQAQRLALARALLRDAPLLLL 497

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 559158796 158 DEPLSALDAKIRISLREEIRAIQQklGITTVFVTHDqEEALSISDRIVVMHEGRADQIGSP 218
Cdd:COG4988  498 DEPTAHLDAETEAEILQALRRLAK--GRTVILITHR-LALLAQADRILVLDDGRIVEQGTH 555
CydC COG4987
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ...
 14-218 3.25e-41

ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444011 [Multi-domain]  Cd Length: 569  Bit Score: 151.84  E-value: 3.25e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  14 GTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQ--RNIGMVFQAYALFpNMT 91
Cdd:COG4987  346 AGRPVLDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDPQSGSITLGGVDLRDLDEDDlrRRIAVVPQRPHLF-DTT 424

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  92 VAQNVSFGlrvsgksRSEI-DATVKEMLSLIRLDHLADRYPY-----------QMSGGQQQRVALARALATKPQVLLLDE 159
Cdd:COG4987  425 LRENLRLA-------RPDAtDEELWAALERVGLGDWLAALPDgldtwlgeggrRLSGGERRRLALARALLRDAPILLLDE 497

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 559158796 160 PLSALDAKIRISLREEIRAIQQklGITTVFVTHDqEEALSISDRIVVMHEGRADQIGSP 218
Cdd:COG4987  498 PTEGLDAATEQALLADLLEALA--GRTVLLITHR-LAGLERMDRILVLEDGRIVEQGTH 553
cbiO PRK13632
cobalt transporter ATP-binding subunit; Provisional
 6-223 2.89e-40

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237452 [Multi-domain]  Cd Length: 271  Bit Score: 142.82  E-value: 2.89e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   6 IKNLKKSFGT--NTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVV--NLRPNQRNIGMVF 81
Cdd:PRK13632  10 VENVSFSYPNseNNALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIKIDGITISkeNLKEIRKKIGIIF 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  82 Q-AYALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEP 160
Cdd:PRK13632  90 QnPDNQFIGATVEDDIAFGLENKKVPPKKMKDIIDDLAKKVGMEDYLDKEPQNLSGGQKQRVAIASVLALNPEIIIFDES 169

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 559158796 161 LSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALsISDRIVVMHEGRADQIGSPFDIYN 223
Cdd:PRK13632 170 TSMLDPKGKREIKKIMVDLRKTRKKTLISITHDMDEAI-LADKVIVFSEGKLIAQGKPKEILN 231
ABC_MTABC3_MDL1_MDL2 cd03249
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ...
 16-217 3.86e-40

ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.


Pssm-ID: 213216 [Multi-domain]  Cd Length: 238  Bit Score: 141.52  E-value: 3.86e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  16 NTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDV--VNLRPNQRNIGMVFQAYALFpNMTVA 93
Cdd:cd03249   16 VPILKGLSLTIPPGKTVALVGSSGCGKSTVVSLLERFYDPTSGEILLDGVDIrdLNLRWLRSQIGLVSQEPVLF-DGTIA 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  94 QNVSFGLRvsgksrseiDATVKEMLSLIRL-------DHLADRY-----PY--QMSGGQQQRVALARALATKPQVLLLDE 159
Cdd:cd03249   95 ENIRYGKP---------DATDEEVEEAAKKanihdfiMSLPDGYdtlvgERgsQLSGGQKQRIAIARALLRNPKILLLDE 165

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 559158796 160 PLSALDAkirislrEEIRAIQQKL-----GITTVFVTHdqeeALSI---SDRIVVMHEGRADQIGS 217
Cdd:cd03249  166 ATSALDA-------ESEKLVQEALdramkGRTTIVIAH----RLSTirnADLIAVLQNGQVVEQGT 220
dppF PRK11308
dipeptide transporter ATP-binding subunit; Provisional
 22-225 3.93e-40

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 236898 [Multi-domain]  Cd Length: 327  Bit Score: 143.95  E-value: 3.93e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  22 FNLAVGKGEFVsfLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVV--------NLRpnqRNIGMVFQ-AYA-LFPNMT 91
Cdd:PRK11308  36 FTLERGKTLAV--VGESGCGKSTLARLLTMIETPTGGELYYQGQDLLkadpeaqkLLR---QKIQIVFQnPYGsLNPRKK 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  92 VAQNVSFGLRVSGK-SRSEIDATVKEMLSLI--RLDHlADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSALDAKI 168
Cdd:PRK11308 111 VGQILEEPLLINTSlSAAERREKALAMMAKVglRPEH-YDRYPHMFSGGQRQRIAIARALMLDPDVVVADEPVSALDVSV 189

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 559158796 169 RISLREEIRAIQQKLGITTVFVTHDqeeaLS----ISDRIVVMHEGRADQIGSPFDIYNRP 225
Cdd:PRK11308 190 QAQVLNLMMDLQQELGLSYVFISHD----LSvvehIADEVMVMYLGRCVEKGTKEQIFNNP 246
urea_trans_UrtE TIGR03410
urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC ...
 4-211 5.05e-40

urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC transporter ATP-binding subunits associated with urea transport and metabolism. This protein is found in a conserved five-gene transport operon typically found adjacent to urease genes. It was shown in Cyanobacteria that disruption leads to the loss of high-affinity urea transport activity. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274567 [Multi-domain]  Cd Length: 230  Bit Score: 140.74  E-value: 5.05e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796    4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQR---NIGMV 80
Cdd:TIGR03410   1 LEVSNLNVYYGQSHILRGVSLEVPKGEVTCVLGRNGVGKTTLLKTLMGLLPVKSGSIRLDGEDITKLPPHERaraGIAYV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   81 FQAYALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLirLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEP 160
Cdd:TIGR03410  81 PQGREIFPRLTVEENLLTGLAALPRRSRKIPDEIYELFPV--LKEMLGRRGGDLSGGQQQQLAIARALVTRPKLLLLDEP 158

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 559158796  161 LSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGR 211
Cdd:TIGR03410 159 TEGIQPSIIKDIGRVIRRLRAEGGMAILLVEQYLDFARELADRYYVMERGR 209
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
 1-211 5.72e-40

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 147.91  E-value: 5.72e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   1 MAFLNIKNLKKSFGTN----TVVHDFNLAVGKGEFVSFLGPSGCGKT----TVLRMIAGFETPDNGSIEIDGKDVVNLRP 72
Cdd:COG4172    4 MPLLSVEDLSVAFGQGggtvEAVKGVSFDIAAGETLALVGESGSGKSvtalSILRLLPDPAAHPSGSILFDGQDLLGLSE 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  73 NQ------RNIGMVFQ--AYALFPNMTVAQNVSFGLRV-SGKSRSEIDATVKEMLSLIRLDHLA---DRYPYQMSGGQQQ 140
Cdd:COG4172   84 RElrrirgNRIAMIFQepMTSLNPLHTIGKQIAEVLRLhRGLSGAAARARALELLERVGIPDPErrlDAYPHQLSGGQRQ 163

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 559158796 141 RVALARALATKPQVLLLDEPLSALDAKIRISLREEIRAIQQKLGITTVFVTHDqeeaLSI----SDRIVVMHEGR 211
Cdd:COG4172  164 RVMIAMALANEPDLLIADEPTTALDVTVQAQILDLLKDLQRELGMALLLITHD----LGVvrrfADRVAVMRQGE 234
PRK15079 PRK15079
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
 4-225 6.44e-40

oligopeptide ABC transporter ATP-binding protein OppF; Provisional


Pssm-ID: 185037 [Multi-domain]  Cd Length: 331  Bit Score: 143.69  E-value: 6.44e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFG-------------TNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNL 70
Cdd:PRK15079   9 LEVADLKVHFDikdgkqwfwqppkTLKAVDGVTLRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGEVAWLGKDLLGM 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  71 RPNQR-----NIGMVFQ--AYALFPNMTVAQNVSFGLRV--SGKSRSEIDATVKEMLSLIRL-DHLADRYPYQMSGGQQQ 140
Cdd:PRK15079  89 KDDEWravrsDIQMIFQdpLASLNPRMTIGEIIAEPLRTyhPKLSRQEVKDRVKAMMLKVGLlPNLINRYPHEFSGGQCQ 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 141 RVALARALATKPQVLLLDEPLSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFD 220
Cdd:PRK15079 169 RIGIARALILEPKLIICDEPVSALDVSIQAQVVNLLQQLQREMGLSLIFIAHDLAVVKHISDRVLVMYLGHAVELGTYDE 248


                 ....*
gi 559158796 221 IYNRP 225
Cdd:PRK15079 249 VYHNP 253
PRK13537 PRK13537
nodulation factor ABC transporter ATP-binding protein NodI;
2-218 3.16e-39

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237420 [Multi-domain]  Cd Length: 306  Bit Score: 141.10  E-value: 3.16e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   2 AFLNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQR-NIGMV 80
Cdd:PRK13537   6 APIDFRNVEKRYGDKLVVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLCGEPVPSRARHARqRVGVV 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  81 FQAYALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEP 160
Cdd:PRK13537  86 PQFDNLDPDFTVRENLLVFGRYFGLSAAAARALVPPLLEFAKLENKADAKVGELSGGMKRRLTLARALVNDPDVLVLDEP 165

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 559158796 161 LSALDAKIRISLREEIRAIQQKlGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSP 218
Cdd:PRK13537 166 TTGLDPQARHLMWERLRSLLAR-GKTILLTTHFMEEAERLCDRLCVIEEGRKIAEGAP 222
PRK13536 PRK13536
nodulation factor ABC transporter ATP-binding protein NodI;
4-221 4.26e-39

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237419 [Multi-domain]  Cd Length: 340  Bit Score: 141.51  E-value: 4.26e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDV-VNLRPNQRNIGMVFQ 82
Cdd:PRK13536  42 IDLAGVSKSYGDKAVVNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKITVLGVPVpARARLARARIGVVPQ 121

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  83 AYALFPNMTVAQN-VSFGlRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPL 161
Cdd:PRK13536 122 FDNLDLEFTVRENlLVFG-RYFGMSTREIEAVIPSLLEFARLESKADARVSDLSGGMKRRLTLARALINDPQLLILDEPT 200

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 162 SALDAKIRISLREEIRAIQQKlGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDI 221
Cdd:PRK13536 201 TGLDPHARHLIWERLRSLLAR-GKTILLTTHFMEEAERLCDRLCVLEAGRKIAEGRPHAL 259
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
 4-211 4.71e-39

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 144.78  E-value: 4.71e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQ---RNIGMV 80
Cdd:COG3845    6 LELRGITKRFGGVVANDDVSLTVRPGEIHALLGENGAGKSTLMKILYGLYQPDSGEILIDGKPVRIRSPRDaiaLGIGMV 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  81 FQAYALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLA---DRYPYQMSGGQQQRVALARALATKPQVLLL 157
Cdd:COG3845   86 HQHFMLVPNLTVAENIVLGLEPTKGGRLDRKAARARIRELSERYGLDvdpDAKVEDLSVGEQQRVEILKALYRGARILIL 165

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 559158796 158 DEPLSAL-----DAKIRI--SLREEiraiqqklGITTVFVTHDQEEALSISDRIVVMHEGR 211
Cdd:COG3845  166 DEPTAVLtpqeaDELFEIlrRLAAE--------GKSIIFITHKLREVMAIADRVTVLRRGK 218
PRK14267 PRK14267
phosphate ABC transporter ATP-binding protein; Provisional
 4-234 4.54e-38

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184596 [Multi-domain]  Cd Length: 253  Bit Score: 136.51  E-value: 4.54e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGF-----ETPDNGSIEIDGKDVVNLRPN----Q 74
Cdd:PRK14267   5 IETVNLRVYYGSNHVIKGVDLKIPQNGVFALMGPSGCGKSTLLRTFNRLlelneEARVEGEVRLFGRNIYSPDVDpievR 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  75 RNIGMVFQAYALFPNMTVAQNVSFGLRVSG--KSRSEIDATVKEMLSLIRL-DHLADR---YPYQMSGGQQQRVALARAL 148
Cdd:PRK14267  85 REVGMVFQYPNPFPHLTIYDNVAIGVKLNGlvKSKKELDERVEWALKKAALwDEVKDRlndYPSNLSGGQRQRLVIARAL 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 149 ATKPQVLLLDEPLSALD----AKIrislrEEIrAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNR 224
Cdd:PRK14267 165 AMKPKILLMDEPTANIDpvgtAKI-----EEL-LFELKKEYTIVLVTHSPAQAARVSDYVAFLYLGKLIEVGPTRKVFEN 238

                        250
                 ....*....|
gi 559158796 225 PASRFVASFV 234
Cdd:PRK14267 239 PEHELTEKYV 248
PRK14247 PRK14247
phosphate ABC transporter ATP-binding protein; Provisional
 1-234 7.29e-38

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172735 [Multi-domain]  Cd Length: 250  Bit Score: 135.81  E-value: 7.29e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   1 MAFLNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGF-----ETPDNGSIEIDGKD-----VVNL 70
Cdd:PRK14247   1 MNKIEIRDLKVSFGQVEVLDGVNLEIPDNTITALMGPSGSGKSTLLRVFNRLielypEARVSGEVYLDGQDifkmdVIEL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  71 RpnqRNIGMVFQAYALFPNMTVAQNVSFGLRVS--GKSRSEIDATVKEMLSLIRL-DHLADRY---PYQMSGGQQQRVAL 144
Cdd:PRK14247  81 R---RRVQMVFQIPNPIPNLSIFENVALGLKLNrlVKSKKELQERVRWALEKAQLwDEVKDRLdapAGKLSGGQQQRLCI 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 145 ARALATKPQVLLLDEPLSALD----AKIrislreEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFD 220
Cdd:PRK14247 158 ARALAFQPEVLLADEPTANLDpentAKI------ESLFLELKKDMTIVLVTHFPQQAARISDYVAFLYKGQIVEWGPTRE 231

                        250
                 ....*....|....
gi 559158796 221 IYNRPASRFVASFV 234
Cdd:PRK14247 232 VFTNPRHELTEKYV 245
ABC_Carb_Monos_II cd03215
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ...
 18-211 9.55e-38

Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213182 [Multi-domain]  Cd Length: 182  Bit Score: 133.33  E-value: 9.55e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  18 VVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQR-NIGMVF-----QAYALFPNMT 91
Cdd:cd03215   15 AVRDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGEITLDGKPVTRRSPRDAiRAGIAYvpedrKREGLVLDLS 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  92 VAQNVSFglrvsgksrseidatvkemlslirldhladryPYQMSGGQQQRVALARALATKPQVLLLDEPLSALDakirIS 171
Cdd:cd03215   95 VAENIAL--------------------------------SSLLSGGNQQKVVLARWLARDPRVLILDEPTRGVD----VG 138

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 559158796 172 LREEIRAIQQKL---GITTVFVTHDQEEALSISDRIVVMHEGR 211
Cdd:cd03215  139 AKAEIYRLIRELadaGKAVLLISSELDELLGLCDRILVMYEGR 181
ABC_cobalt_CbiO_domain2 cd03226
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ...
 6-210 1.25e-37

Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213193 [Multi-domain]  Cd Length: 205  Bit Score: 133.92  E-value: 1.25e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   6 IKNLKKSFGTNT-VVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVvNLRPNQRNIGMVFQ-- 82
Cdd:cd03226    2 IENISFSYKKGTeILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSGSILLNGKPI-KAKERRKSIGYVMQdv 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  83 AYALFPNmTVAQNVSFGLRVSGKSRSEIDatvkEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLS 162
Cdd:cd03226   81 DYQLFTD-SVREELLLGLKELDAGNEQAE----TVLKDLDLYALKERHPLSLSGGQKQRLAIAAALLSGKDLLIFDEPTS 155

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 559158796 163 ALDAKIRISLREEIRAIqQKLGITTVFVTHDQEEALSISDRIVVMHEG 210
Cdd:cd03226  156 GLDYKNMERVGELIREL-AAQGKAVIVITHDYEFLAKVCDRVLLLANG 202
PRK14239 PRK14239
phosphate transporter ATP-binding protein; Provisional
 2-228 1.40e-37

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184585 [Multi-domain]  Cd Length: 252  Bit Score: 135.29  E-value: 1.40e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   2 AFLNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGF-----ETPDNGSIEIDGK-------DVVN 69
Cdd:PRK14239   4 PILQVSDLSVYYNKKKALNSVSLDFYPNEITALIGPSGSGKSTLLRSINRMndlnpEVTITGSIVYNGHniysprtDTVD 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  70 LRpnqRNIGMVFQAYALFPnMTVAQNVSFGLRVSG-KSRSEIDATVKEMLSLIRL-----DHLADRyPYQMSGGQQQRVA 143
Cdd:PRK14239  84 LR---KEIGMVFQQPNPFP-MSIYENVVYGLRLKGiKDKQVLDEAVEKSLKGASIwdevkDRLHDS-ALGLSGGQQQRVC 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 144 LARALATKPQVLLLDEPLSALDAKIRISLREEIRAIQQKLgiTTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYN 223
Cdd:PRK14239 159 IARVLATSPKIILLDEPTSALDPISAGKIEETLLGLKDDY--TMLLVTRSMQQASRISDRTGFFLDGDLIEYNDTKQMFM 236


                 ....*
gi 559158796 224 RPASR 228
Cdd:PRK14239 237 NPKHK 241
livG PRK11300
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
 4-225 2.76e-37

leucine/isoleucine/valine transporter ATP-binding subunit; Provisional


Pssm-ID: 183080 [Multi-domain]  Cd Length: 255  Bit Score: 134.35  E-value: 2.76e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLrPNQR--NIGMV- 80
Cdd:PRK11300   6 LSVSGLMMRFGGLLAVNNVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTILLRGQHIEGL-PGHQiaRMGVVr 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  81 -FQAYALFPNMT------VAQ------NVSFGL-RVSGKSRSEIDATVKEM--LSLIRLDHLADRYPYQMSGGQQQRVAL 144
Cdd:PRK11300  85 tFQHVRLFREMTvienllVAQhqqlktGLFSGLlKTPAFRRAESEALDRAAtwLERVGLLEHANRQAGNLAYGQQRRLEI 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 145 ARALATKPQVLLLDEPLSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNR 224
Cdd:PRK11300 165 ARCMVTQPEILMLDEPAAGLNPKETKELDELIAELRNEHNVTVLLIEHDMKLVMGISDRIYVVNQGTPLANGTPEEIRNN 244


                 .
gi 559158796 225 P 225
Cdd:PRK11300 245 P 245
btuD PRK09536
corrinoid ABC transporter ATPase; Reviewed
 1-236 2.97e-37

corrinoid ABC transporter ATPase; Reviewed


Pssm-ID: 236554 [Multi-domain]  Cd Length: 402  Bit Score: 138.05  E-value: 2.97e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   1 MAFLNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNL--RPNQRNIG 78
Cdd:PRK09536   1 MPMIDVSDLSVEFGDTTVLDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLVAGDDVEALsaRAASRRVA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  79 MVFQAYALFPNMTVAQNVSFGlRVSGKSR-----SEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQ 153
Cdd:PRK09536  81 SVPQDTSLSFEFDVRQVVEMG-RTPHRSRfdtwtETDRAAVERAMERTGVAQFADRPVTSLSGGERQRVLLARALAQATP 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 154 VLLLDEPLSALDAKIRISLREEIRAIQQKlGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNRPASR--FVA 231
Cdd:PRK09536 160 VLLLDEPTASLDINHQVRTLELVRRLVDD-GKTAVAAIHDLDLAARYCDELVLLADGRVRAAGPPADVLTADTLRaaFDA 238


                 ....*.
gi 559158796 232 -SFVGT 236
Cdd:PRK09536 239 rTAVGT 244
fecE PRK11231
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
4-221 3.21e-37

Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;


Pssm-ID: 183044 [Multi-domain]  Cd Length: 255  Bit Score: 134.37  E-value: 3.21e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQ--RNIGMVF 81
Cdd:PRK11231   3 LRTENLTVGYGTKRILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDKPISMLSSRQlaRRLALLP 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  82 QAYALFPNMTVAQNVSFG----LRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLL 157
Cdd:PRK11231  83 QHHLTPEGITVRELVAYGrspwLSLWGRLSAEDNARVNQAMEQTRINHLADRRLTDLSGGQRQRAFLAMVLAQDTPVVLL 162

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 559158796 158 DEPLSALDAKIRISLREEIRAIQQKlGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDI 221
Cdd:PRK11231 163 DEPTTYLDINHQVELMRLMRELNTQ-GKTVVTVLHDLNQASRYCDHLVVLANGHVMAQGTPEEV 225
PhnL COG4778
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ...
 4-211 3.55e-37

Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];


Pssm-ID: 443809 [Multi-domain]  Cd Length: 229  Bit Score: 133.33  E-value: 3.55e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSF------GTN-TVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKD---------- 66
Cdd:COG4778    5 LEVENLSKTFtlhlqgGKRlPVLDGVSFSVAAGECVALTGPSGAGKSTLLKCIYGNYLPDSGSILVRHDGgwvdlaqasp 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  67 --VVNLRpnQRNIGMVFQAYALFPNMT----VAQnvsfGLRVSGKSRSEIDATVKEMLSLIRLD-HLADRYPYQMSGGQQ 139
Cdd:COG4778   85 reILALR--RRTIGYVSQFLRVIPRVSaldvVAE----PLLERGVDREEARARARELLARLNLPeRLWDLPPATFSGGEQ 158

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 559158796 140 QRVALARALATKPQVLLLDEPLSALDAKIRISLREEIRAIQQKlGITTVFVTHDQEEALSISDRIVVMHEGR 211
Cdd:COG4778  159 QRVNIARGFIADPPLLLLDEPTASLDAANRAVVVELIEEAKAR-GTAIIGIFHDEEVREAVADRVVDVTPFS 229
PRK11831 PRK11831
phospholipid ABC transporter ATP-binding protein MlaF;
4-228 5.53e-36

phospholipid ABC transporter ATP-binding protein MlaF;


Pssm-ID: 236997 [Multi-domain]  Cd Length: 269  Bit Score: 131.43  E-value: 5.53e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQ-----RNIG 78
Cdd:PRK11831   8 VDMRGVSFTRGNRCIFDNISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHGEILFDGENIPAMSRSRlytvrKRMS 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  79 MVFQAYALFPNMTVAQNVSFGLRVSGKSRSEI-DATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLL 157
Cdd:PRK11831  88 MLFQSGALFTDMNVFDNVAYPLREHTQLPAPLlHSTVMMKLEAVGLRGAAKLMPSELSGGMARRAALARAIALEPDLIMF 167

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 559158796 158 DEPLSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNRPASR 228
Cdd:PRK11831 168 DEPFVGQDPITMGVLVKLISELNSALGVTCVVVSHDVPEVLSIADHAYIVADKKIVAHGSAQALQANPDPR 238
cbiO PRK13640
energy-coupling factor transporter ATPase;
18-225 5.85e-36

energy-coupling factor transporter ATPase;


Pssm-ID: 184200 [Multi-domain]  Cd Length: 282  Bit Score: 131.85  E-value: 5.85e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  18 VVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPD---NGSIEIDG-----KDVVNLRpnqRNIGMVFQ-AYALFP 88
Cdd:PRK13640  22 ALNDISFSIPRGSWTALIGHNGSGKSTISKLINGLLLPDdnpNSKITVDGitltaKTVWDIR---EKVGIVFQnPDNQFV 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  89 NMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSALDAKI 168
Cdd:PRK13640  99 GATVGDDVAFGLENRAVPRPEMIKIVRDVLADVGMLDYIDSEPANLSGGQKQRVAIAGILAVEPKIIILDESTSMLDPAG 178

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 559158796 169 RISLREEIRAIQQKLGITTVFVTHDQEEAlSISDRIVVMHEGRADQIGSPFDIYNRP 225
Cdd:PRK13640 179 KEQILKLIRKLKKKNNLTVISITHDIDEA-NMADQVLVLDDGKLLAQGSPVEIFSKV 234
ABCC_Protease_Secretion cd03246
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ...
 14-212 1.09e-35

ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.


Pssm-ID: 213213 [Multi-domain]  Cd Length: 173  Bit Score: 127.72  E-value: 1.09e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  14 GTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQ--RNIGMVFQAYALFPNmT 91
Cdd:cd03246   13 AEPPVLRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRLDGADISQWDPNElgDHVGYLPQDDELFSG-S 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  92 VAQNVsfglrvsgksrseidatvkemlslirldhladrypyqMSGGQQQRVALARALATKPQVLLLDEPLSALDAKIRIS 171
Cdd:cd03246   92 IAENI-------------------------------------LSGGQRQRLGLARALYGNPRILVLDEPNSHLDVEGERA 134

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 559158796 172 LREEIRAIqQKLGITTVFVTHdQEEALSISDRIVVMHEGRA 212
Cdd:cd03246  135 LNQAIAAL-KAAGATRIVIAH-RPETLASADRILVLEDGRV 173
ABCC_MsbA cd03251
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ...
 18-217 2.08e-35

ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213218 [Multi-domain]  Cd Length: 234  Bit Score: 128.89  E-value: 2.08e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  18 VVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDV--VNLRPNQRNIGMVFQAYALFpNMTVAQN 95
Cdd:cd03251   17 VLRDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDVDSGRILIDGHDVrdYTLASLRRQIGLVSQDVFLF-NDTVAEN 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  96 VSFGLRvsGKSRSEIDATVKEMLSLIRLDHLADRYP-------YQMSGGQQQRVALARALATKPQVLLLDEPLSALDAki 168
Cdd:cd03251   96 IAYGRP--GATREEVEEAARAANAHEFIMELPEGYDtvigergVKLSGGQRQRIAIARALLKDPPILILDEATSALDT-- 171

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 559158796 169 rislrEEIRAIQQKL-----GITTVFVTHdqeeALSI---SDRIVVMHEGRADQIGS 217
Cdd:cd03251  172 -----ESERLVQAALerlmkNRTTFVIAH----RLSTienADRIVVLEDGKIVERGT 219
nickel_nikD TIGR02770
nickel import ATP-binding protein NikD; This family represents the NikD subunit of a ...
 19-235 2.21e-35

nickel import ATP-binding protein NikD; This family represents the NikD subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. NikD and NikE are homologous. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 131817 [Multi-domain]  Cd Length: 230  Bit Score: 128.64  E-value: 2.21e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   19 VHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPD----NGSIEIDGKDVVNLRPNQRNIGMVFQA--YALFPNMTV 92
Cdd:TIGR02770   2 VQDLNLSLKRGEVLALVGESGSGKSLTCLAILGLLPPGltqtSGEILLDGRPLLPLSIRGRHIATIMQNprTAFNPLFTM 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   93 AQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDH---LADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSALDAKIR 169
Cdd:TIGR02770  82 GNHAIETLRSLGKLSKQARALILEALEAVGLPDpeeVLKKYPFQLSGGMLQRVMIALALLLEPPFLIADEPTTDLDVVNQ 161

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 559158796  170 ISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNRPASRFVASFVG 235
Cdd:TIGR02770 162 ARVLKLLRELRQLFGTGILLITHDLGVVARIADEVAVMDDGRIVERGTVKEIFYNPKHETTRKLLS 227
PRK13633 PRK13633
energy-coupling factor transporter ATPase;
17-222 4.93e-35

energy-coupling factor transporter ATPase;


Pssm-ID: 237453 [Multi-domain]  Cd Length: 280  Bit Score: 129.44  E-value: 4.93e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  17 TVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDG---KDVVNLRPNQRNIGMVFQAyalfP-NMTV 92
Cdd:PRK13633  24 LALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKVYVDGldtSDEENLWDIRNKAGMVFQN----PdNQIV 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  93 A----QNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSALDAKI 168
Cdd:PRK13633 100 AtiveEDVAFGPENLGIPPEEIRERVDESLKKVGMYEYRRHAPHLLSGGQKQRVAIAGILAMRPECIIFDEPTAMLDPSG 179

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 559158796 169 RISLREEIRAIQQKLGITTVFVTHDQEEALSiSDRIVVMHEGRADQIGSPFDIY 222
Cdd:PRK13633 180 RREVVNTIKELNKKYGITIILITHYMEEAVE-ADRIIVMDSGKVVMEGTPKEIF 232
cbiO PRK13649
energy-coupling factor transporter ATPase;
21-224 7.11e-35

energy-coupling factor transporter ATPase;


Pssm-ID: 184208 [Multi-domain]  Cd Length: 280  Bit Score: 128.71  E-value: 7.11e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  21 DFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVN------LRPNQRNIGMVFQayalFPNM---- 90
Cdd:PRK13649  25 DVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVRVDDTLITStsknkdIKQIRKKVGLVFQ----FPESqlfe 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  91 -TVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDH-LADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSALDAKI 168
Cdd:PRK13649 101 eTVLKDVAFGPQNFGVSQEEAEALAREKLALVGISEsLFEKNPFELSGGQMRRVAIAGILAMEPKILVLDEPTAGLDPKG 180

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 559158796 169 RISLREEIRAIQQKlGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNR 224
Cdd:PRK13649 181 RKELMTLFKKLHQS-GMTIVLVTHLMDDVANYADFVYVLEKGKLVLSGKPKDIFQD 235
ABCC_ATM1_transporter cd03253
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ...
 12-218 1.22e-34

ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213220 [Multi-domain]  Cd Length: 236  Bit Score: 126.96  E-value: 1.22e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  12 SFGTNT---VVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDV--VNLRPNQRNIGMVFQAYAL 86
Cdd:cd03253    7 TFAYDPgrpVLKDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSILIDGQDIreVTLDSLRRAIGVVPQDTVL 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  87 FpNMTVAQNVSFGlrvsgksrsEIDATVKEMLSLIRLDHLAD---RYP--YQ---------MSGGQQQRVALARALATKP 152
Cdd:cd03253   87 F-NDTIGYNIRYG---------RPDATDEEVIEAAKAAQIHDkimRFPdgYDtivgerglkLSGGEKQRVAIARAILKNP 156

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 559158796 153 QVLLLDEPLSALDakiriSLREeiRAIQQKL-----GITTVFVTHDQEEALSiSDRIVVMHEGRADQIGSP 218
Cdd:cd03253  157 PILLLDEATSALD-----THTE--REIQAALrdvskGRTTIVIAHRLSTIVN-ADKIIVLKDGRIVERGTH 219
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
4-211 1.71e-34

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 132.06  E-value: 1.71e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLkksfGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQ--RNiGMVF 81
Cdd:COG1129  257 LEVEGL----SVGGVVRDVSFSVRAGEILGIAGLVGAGRTELARALFGADPADSGEIRLDGKPVRIRSPRDaiRA-GIAY 331

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  82 -----QAYALFPNMTVAQNVSFGL--RVSGK---SRSEIDATVKEMLSL--IRLDHladryPYQ----MSGGQQQRVALA 145
Cdd:COG1129  332 vpedrKGEGLVLDLSIRENITLASldRLSRGgllDRRRERALAEEYIKRlrIKTPS-----PEQpvgnLSGGNQQKVVLA 406

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 559158796 146 RALATKPQVLLLDEPLSALD--AKirislrEEIRAIQQKL---GITTVFVTHDQEEALSISDRIVVMHEGR 211
Cdd:COG1129  407 KWLATDPKVLILDEPTRGIDvgAK------AEIYRLIRELaaeGKAVIVISSELPELLGLSDRILVMREGR 471
cbiO PRK13642
energy-coupling factor transporter ATPase;
4-222 3.10e-34

energy-coupling factor transporter ATPase;


Pssm-ID: 184202 [Multi-domain]  Cd Length: 277  Bit Score: 127.13  E-value: 3.10e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFN---LAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGK-----DVVNLRpnqR 75
Cdd:PRK13642   5 LEVENLVFKYEKESDVNQLNgvsFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGKVKIDGElltaeNVWNLR---R 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  76 NIGMVFQ-AYALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQV 154
Cdd:PRK13642  82 KIGMVFQnPDNQFVGATVEDDVAFGMENQGIPREEMIKRVDEALLAVNMLDFKTREPARLSGGQKQRVAVAGIIALRPEI 161

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 559158796 155 LLLDEPLSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSiSDRIVVMHEGRADQIGSPFDIY 222
Cdd:PRK13642 162 IILDESTSMLDPTGRQEIMRVIHEIKEKYQLTVLSITHDLDEAAS-SDRILVMKAGEIIKEAAPSELF 228
PRK14258 PRK14258
phosphate ABC transporter ATP-binding protein; Provisional
 4-225 5.04e-34

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184593 [Multi-domain]  Cd Length: 261  Bit Score: 126.30  E-value: 5.04e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGF-----ETPDNGSIEIDGKDV----VNLRPNQ 74
Cdd:PRK14258   8 IKVNNLSFYYDTQKILEGVSMEIYQSKVTAIIGPSGCGKSTFLKCLNRMnelesEVRVEGRVEFFNQNIyerrVNLNRLR 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  75 RNIGMVFQAYALFPnMTVAQNVSFGLRVSG-KSRSEIDATVKEMLSLIRL----DHLADRYPYQMSGGQQQRVALARALA 149
Cdd:PRK14258  88 RQVSMVHPKPNLFP-MSVYDNVAYGVKIVGwRPKLEIDDIVESALKDADLwdeiKHKIHKSALDLSGGQQQRLCIARALA 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 150 TKPQVLLLDEPLSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMH--EGRADQI---GSPFDIYNR 224
Cdd:PRK14258 167 VKPKVLLMDEPCFGLDPIASMKVESLIQSLRLRSELTMVIVSHNLHQVSRLSDFTAFFKgnENRIGQLvefGLTKKIFNS 246


                 .
gi 559158796 225 P 225
Cdd:PRK14258 247 P 247
ArpD COG4618
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ...
 14-216 5.83e-34

ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 443660 [Multi-domain]  Cd Length: 563  Bit Score: 131.41  E-value: 5.83e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  14 GTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQ--RNIGMVFQAYALFPNmT 91
Cdd:COG4618  343 SKRPILRGVSFSLEPGEVLGVIGPSGSGKSTLARLLVGVWPPTAGSVRLDGADLSQWDREElgRHIGYLPQDVELFDG-T 421

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  92 VAQNVS-FGlrvsgksrsEID----------ATVKEMLSlirldHLADRY-------PYQMSGGQQQRVALARALATKPQ 153
Cdd:COG4618  422 IAENIArFG---------DADpekvvaaaklAGVHEMIL-----RLPDGYdtrigegGARLSGGQRQRIGLARALYGDPR 487

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 559158796 154 VLLLDEPLSALDAKIRISLREEIRAIQQKlGITTVFVTHDQeEALSISDRIVVMHEGRADQIG 216
Cdd:COG4618  488 LVVLDEPNSNLDDEGEAALAAAIRALKAR-GATVVVITHRP-SLLAAVDKLLVLRDGRVQAFG 548
cbiO PRK13648
cobalt transporter ATP-binding subunit; Provisional
 21-223 6.76e-34

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184207 [Multi-domain]  Cd Length: 269  Bit Score: 126.02  E-value: 6.76e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  21 DFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVV--NLRPNQRNIGMVFQ-AYALFPNMTVAQNVS 97
Cdd:PRK13648  27 DVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIFYNNQAITddNFEKLRKHIGIVFQnPDNQFVGSIVKYDVA 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  98 FGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSALDAKIRISLREEIR 177
Cdd:PRK13648 107 FGLENHAVPYDEMHRRVSEALKQVDMLERADYEPNALSGGQKQRVAIAGVLALNPSVIILDEATSMLDPDARQNLLDLVR 186

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 559158796 178 AIQQKLGITTVFVTHDQEEALSiSDRIVVMHEGRADQIGSPFDIYN 223
Cdd:PRK13648 187 KVKSEHNITIISITHDLSEAME-ADHVIVMNKGTVYKEGTPTEIFD 231
PRK09984 PRK09984
phosphonate ABC transporter ATP-binding protein;
4-210 1.29e-33

phosphonate ABC transporter ATP-binding protein;


Pssm-ID: 182182 [Multi-domain]  Cd Length: 262  Bit Score: 125.13  E-value: 1.29e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNG----------SIEIDGKDVVNLRPN 73
Cdd:PRK09984   5 IRVEKLAKTFNQHQALHAVDLNIHHGEMVALLGPSGSGKSTLLRHLSGLITGDKSagshiellgrTVQREGRLARDIRKS 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  74 QRNIGMVFQAYALFPNMTVAQNVSFGLR---------VSGKSRSEIDATVkEMLSLIRLDHLADRYPYQMSGGQQQRVAL 144
Cdd:PRK09984  85 RANTGYIFQQFNLVNRLSVLENVLIGALgstpfwrtcFSWFTREQKQRAL-QALTRVGMVHFAHQRVSTLSGGQQQRVAI 163

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 559158796 145 ARALATKPQVLLLDEPLSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEG 210
Cdd:PRK09984 164 ARALMQQAKVILADEPIASLDPESARIVMDTLRDINQNDGITVVVTLHQVDYALRYCERIVALRQG 229
ABCC_bacteriocin_exporters cd03245
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ...
 16-211 1.60e-33

ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.


Pssm-ID: 213212 [Multi-domain]  Cd Length: 220  Bit Score: 123.47  E-value: 1.60e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  16 NTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPN--QRNIGMVFQAYALFpNMTVA 93
Cdd:cd03245   17 IPALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLDGTDIRQLDPAdlRRNIGYVPQDVTLF-YGTLR 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  94 QNVSFGLRVSGksrseiDATVKEMLSLIRLDHLADRYP-----------YQMSGGQQQRVALARALATKPQVLLLDEPLS 162
Cdd:cd03245   96 DNITLGAPLAD------DERILRAAELAGVTDFVNKHPngldlqigergRGLSGGQRQAVALARALLNDPPILLLDEPTS 169

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 559158796 163 ALDakiRISLREEIRAIQQKL-GITTVFVTHDQeEALSISDRIVVMHEGR 211
Cdd:cd03245  170 AMD---MNSEERLKERLRQLLgDKTLIIITHRP-SLLDLVDRIIVMDSGR 215
cbiO PRK13647
cobalt transporter ATP-binding subunit; Provisional
 24-218 2.25e-33

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237457 [Multi-domain]  Cd Length: 274  Bit Score: 124.85  E-value: 2.25e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  24 LAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVV--NLRPNQRNIGMVFQAY--ALFpNMTVAQNVSFG 99
Cdd:PRK13647  26 LSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGRVKVMGREVNaeNEKWVRSKVGLVFQDPddQVF-SSTVWDDVAFG 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 100 LRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSALDAKIRISLReEIRAI 179
Cdd:PRK13647 105 PVNMGLDKDEVERRVEEALKAVRMWDFRDKPPYHLSYGQKKRVAIAGVLAMDPDVIVLDEPMAYLDPRGQETLM-EILDR 183

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 559158796 180 QQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSP 218
Cdd:PRK13647 184 LHNQGKTVIVATHDVDLAAEWADQVIVLKEGRVLAEGDK 222
PRK10908 PRK10908
cell division ATP-binding protein FtsE;
21-211 3.63e-33

cell division ATP-binding protein FtsE;


Pssm-ID: 182829 [Multi-domain]  Cd Length: 222  Bit Score: 122.68  E-value: 3.63e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  21 DFNLAVGKGEFVSflGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQ-----RNIGMVFQAYALFPNMTVAQN 95
Cdd:PRK10908  22 TFHMRPGEMAFLT--GHSGAGKSTLLKLICGIERPSAGKIWFSGHDITRLKNREvpflrRQIGMIFQDHHLLMDRTVYDN 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  96 VSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSALDAKIR---ISL 172
Cdd:PRK10908 100 VAIPLIIAGASGDDIRRRVSAALDKVGLLDKAKNFPIQLSGGEQQRVGIARAVVNKPAVLLADEPTGNLDDALSegiLRL 179

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 559158796 173 REEIraiqQKLGITTVFVTHDQEEALSISDRIVVMHEGR 211
Cdd:PRK10908 180 FEEF----NRVGVTVLMATHDIGLISRRSYRMLTLSDGH 214
cbiO PRK13652
cobalt transporter ATP-binding subunit; Provisional
 1-225 3.82e-33

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 172200 [Multi-domain]  Cd Length: 277  Bit Score: 124.14  E-value: 3.82e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   1 MAFLNIKNLKKSFGTNT-VVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVV--NLRPNQRNI 77
Cdd:PRK13652   1 MHLIETRDLCYSYSGSKeALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSVLIRGEPITkeNIREVRKFV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  78 GMVFQAY--ALFpNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVL 155
Cdd:PRK13652  81 GLVFQNPddQIF-SPTVEQDIAFGPINLGLDEETVAHRVSSALHMLGLEELRDRVPHHLSGGEKKRVAIAGVIAMEPQVL 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 156 LLDEPLSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNRP 225
Cdd:PRK13652 160 VLDEPTAGLDPQGVKELIDFLNDLPETYGMTVIFSTHQLDLVPEMADYIYVMDKGRIVAYGTVEEIFLQP 229
ABC_KpsT_Wzt cd03220
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ...
 4-216 4.75e-33

ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.


Pssm-ID: 213187 [Multi-domain]  Cd Length: 224  Bit Score: 122.26  E-value: 4.75e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLrpnqrNIGMVFQa 83
Cdd:cd03220   23 LGILGRKGEVGEFWALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTVTVRGRVSSLL-----GLGGGFN- 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  84 yalfPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRyPYQM-SGGQQQRVALARALATKPQVLLLDEPLS 162
Cdd:cd03220   97 ----PELTGRENIYLNGRLLGLSRKEIDEKIDEIIEFSELGDFIDL-PVKTySSGMKARLAFAIATALEPDILLIDEVLA 171

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 559158796 163 ALDAKIRISLREEIRAIQQKlGITTVFVTHDQEEALSISDRIVVMHEGRADQIG 216
Cdd:cd03220  172 VGDAAFQEKCQRRLRELLKQ-GKTVILVSHDPSSIKRLCDRALVLEKGKIRFDG 224
PRK10535 PRK10535
macrolide ABC transporter ATP-binding protein/permease MacB;
2-239 6.34e-33

macrolide ABC transporter ATP-binding protein/permease MacB;


Pssm-ID: 182528 [Multi-domain]  Cd Length: 648  Bit Score: 129.07  E-value: 6.34e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   2 AFLNIKNLKKSF----GTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQ--- 74
Cdd:PRK10535   3 ALLELKDIRRSYpsgeEQVEVLKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSGTYRVAGQDVATLDADAlaq 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  75 ---RNIGMVFQAYALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATK 151
Cdd:PRK10535  83 lrrEHFGFIFQRYHLLSHLTAAQNVEVPAVYAGLERKQRLLRAQELLQRLGLEDRVEYQPSQLSGGQQQRVSIARALMNG 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 152 PQVLLLDEPLSALDAKIrislREEIRAIQQKL---GITTVFVTHDQEEALSiSDRIVVMHEGR----------ADQIGSP 218
Cdd:PRK10535 163 GQVILADEPTGALDSHS----GEEVMAILHQLrdrGHTVIIVTHDPQVAAQ-AERVIEIRDGEivrnppaqekVNVAGGT 237

                        250       260
                 ....*....|....*....|...
gi 559158796 219 FDIYNRPAS--RFVASFVGTLNM 239
Cdd:PRK10535 238 EPVVNTASGwrQFVSGFREALTM 260
lolD PRK11629
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
18-214 7.60e-33

lipoprotein-releasing ABC transporter ATP-binding protein LolD;


Pssm-ID: 183244 [Multi-domain]  Cd Length: 233  Bit Score: 122.23  E-value: 7.60e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  18 VVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNL----RPNQRN--IGMVFQAYALFPNMT 91
Cdd:PRK11629  24 VLHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNGQPMSKLssaaKAELRNqkLGFIYQFHHLLPDFT 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  92 VAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSALDAKIRIS 171
Cdd:PRK11629 104 ALENVAMPLLIGKKKPAEINSRALEMLAAVGLEHRANHRPSELSGGERQRVAIARALVNNPRLVLADEPTGNLDARNADS 183

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 559158796 172 LREEIRAIQQKLGITTVFVTHDQEEALSISdRIVVMHEGRADQ 214
Cdd:PRK11629 184 IFQLLGELNRLQGTAFLVVTHDLQLAKRMS-RQLEMRDGRLTA 225
PRK14243 PRK14243
phosphate transporter ATP-binding protein; Provisional
 4-234 8.30e-33

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184588 [Multi-domain]  Cd Length: 264  Bit Score: 122.97  E-value: 8.30e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLR-------MIAGFETpdNGSIEIDGK-------DVVN 69
Cdd:PRK14243  11 LRTENLNVYYGSFLAVKNVWLDIPKNQITAFIGPSGCGKSTILRcfnrlndLIPGFRV--EGKVTFHGKnlyapdvDPVE 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  70 LRpnqRNIGMVFQAYALFPNmTVAQNVSFGLRVSGkSRSEIDATVKEMLSLIRL-DHLADRYP---YQMSGGQQQRVALA 145
Cdd:PRK14243  89 VR---RRIGMVFQKPNPFPK-SIYDNIAYGARING-YKGDMDELVERSLRQAALwDEVKDKLKqsgLSLSGGQQQRLCIA 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 146 RALATKPQVLLLDEPLSALDAKIRISLREEIRAIQQKLgiTTVFVTHDQEEALSISDrIVVMHEGRADQIGS------PF 219
Cdd:PRK14243 164 RAIAVQPEVILMDEPCSALDPISTLRIEELMHELKEQY--TIIIVTHNMQQAARVSD-MTAFFNVELTEGGGrygylvEF 240

                        250
                 ....*....|....*....
gi 559158796 220 D----IYNRPASRFVASFV 234
Cdd:PRK14243 241 DrtekIFNSPQQQATRDYV 259
cbiO PRK13639
cobalt transporter ATP-binding subunit; Provisional
 4-225 9.74e-33

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184199 [Multi-domain]  Cd Length: 275  Bit Score: 122.88  E-value: 9.74e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHD-FNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDG-------KDVVNLRpnqR 75
Cdd:PRK13639   2 LETRDLKYSYPDGTEALKgINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEVLIKGepikydkKSLLEVR---K 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  76 NIGMVFQAY--ALFPNmTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQ 153
Cdd:PRK13639  79 TVGIVFQNPddQLFAP-TVEEDVAFGPLNLGLSKEEVEKRVKEALKAVGMEGFENKPPHHLSGGQKKRVAIAGILAMKPE 157

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 559158796 154 VLLLDEPLSALDAKIRISLREEIRAIQQKlGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNRP 225
Cdd:PRK13639 158 IIVLDEPTSGLDPMGASQIMKLLYDLNKE-GITIIISTHDVDLVPVYADKVYVMSDGKIIKEGTPKEVFSDI 228
PRK10895 PRK10895
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
 1-223 1.14e-32

lipopolysaccharide ABC transporter ATP-binding protein; Provisional


Pssm-ID: 182817 [Multi-domain]  Cd Length: 241  Bit Score: 121.92  E-value: 1.14e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   1 MAFLNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDvVNLRP----NQRN 76
Cdd:PRK10895   1 MATLTAKNLAKAYKGRRVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDED-ISLLPlharARRG 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  77 IGMVFQAYALFPNMTVAQNVSFGLRVSGKSRSEIDAT-VKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVL 155
Cdd:PRK10895  80 IGYLPQEASIFRRLSVYDNLMAVLQIRDDLSAEQREDrANELMEEFHIEHLRDSMGQSLSGGERRRVEIARALAANPKFI 159

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 559158796 156 LLDEPLSALDAKIRISLREEIRAIQQKlGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYN 223
Cdd:PRK10895 160 LLDEPFAGVDPISVIDIKRIIEHLRDS-GLGVLITDHNVRETLAVCERAYIVSQGHLIAHGTPTEILQ 226
cbiO PRK13643
energy-coupling factor transporter ATPase;
21-222 1.58e-32

energy-coupling factor transporter ATPase;


Pssm-ID: 184203 [Multi-domain]  Cd Length: 288  Bit Score: 122.92  E-value: 1.58e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  21 DFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIdGKDVVN-------LRPNQRNIGMVFQayalFPNM--- 90
Cdd:PRK13643  24 DIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKVTV-GDIVVSstskqkeIKPVRKKVGVVFQ----FPESqlf 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  91 --TVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLD-HLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSALDAK 167
Cdd:PRK13643  99 eeTVLKDVAFGPQNFGIPKEKAEKIAAEKLEMVGLAdEFWEKSPFELSGGQMRRVAIAGILAMEPEVLVLDEPTAGLDPK 178

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 559158796 168 IRISLREEIRAIQQKlGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIY 222
Cdd:PRK13643 179 ARIEMMQLFESIHQS-GQTVVLVTHLMDDVADYADYVYLLEKGHIISCGTPSDVF 232
NHLM_micro_ABC2 TIGR03797
NHLM bacteriocin system ABC transporter, ATP-binding protein; Members of this protein family ...
 18-225 1.75e-32

NHLM bacteriocin system ABC transporter, ATP-binding protein; Members of this protein family are ABC transporter ATP-binding subunits, part of a three-gene putative bacteriocin transport operon. The other subunits include another ATP-binding subunit (TIGR03796), which has an N-terminal leader sequence cleavage domain, and an HlyD homolog (TIGR03794). In a number of genomes, members of protein families related to nitrile hydratase alpha subunit or to nif11 have undergone paralogous family expansions, with members possessing a putative bacteriocin cleavage region ending with a classic Gly-Gly motif. Those sets of putative bacteriocins, members of this protein family and its partners TIGR03794 and TIGR03796, and cyclodehydratase/docking scaffold fusion proteins of thiazole/oxazole biosynthesis frequently show correlated species distribution and co-clustering within many of those genomes. [Transport and binding proteins, Amino acids, peptides and amines, Cellular processes, Biosynthesis of natural products]


Pssm-ID: 274789 [Multi-domain]  Cd Length: 686  Bit Score: 128.15  E-value: 1.75e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   18 VVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDV--VNLRPNQRNIGMVFQAYALFPNmTVAQN 95
Cdd:TIGR03797 468 ILDDVSLQIEPGEFVAIVGPSGSGKSTLLRLLLGFETPESGSVFYDGQDLagLDVQAVRRQLGVVLQNGRLMSG-SIFEN 546

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   96 VSFGLRVsgksrseidaTVKEMLSLIRLDHLAD---RYPYQM-----------SGGQQQRVALARALATKPQVLLLDEPL 161
Cdd:TIGR03797 547 IAGGAPL----------TLDEAWEAARMAGLAEdirAMPMGMhtvisegggtlSGGQRQRLLIARALVRKPRILLFDEAT 616

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 559158796  162 SALDAKIRISLREEIraiqQKLGITTVFVTHdqeeALSI---SDRIVVMHEGRADQIGSPFDIYNRP 225
Cdd:TIGR03797 617 SALDNRTQAIVSESL----ERLKVTRIVIAH----RLSTirnADRIYVLDAGRVVQQGTYDELMARE 675
cbiO PRK13645
energy-coupling factor transporter ATPase;
23-223 2.45e-32

energy-coupling factor transporter ATPase;


Pssm-ID: 184204 [Multi-domain]  Cd Length: 289  Bit Score: 122.42  E-value: 2.45e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  23 NLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNG-------SIEIDGKDVVNLRPNQRNIGMVFQ--AYALFPNmTVA 93
Cdd:PRK13645  31 SLTFKKNKVTCVIGTTGSGKSTMIQLTNGLIISETGqtivgdyAIPANLKKIKEVKRLRKEIGLVFQfpEYQLFQE-TIE 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  94 QNVSFGLRVSGKSRSEIDATVKEMLSLIRL-DHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSALDAKIRISL 172
Cdd:PRK13645 110 KDIAFGPVNLGENKQEAYKKVPELLKLVQLpEDYVKRSPFELSGGQKRRVALAGIIAMDGNTLVLDEPTGGLDPKGEEDF 189

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 559158796 173 REEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYN 223
Cdd:PRK13645 190 INLFERLNKEYKKRIIMVTHNMDQVLRIADEVIVMHEGKVISIGSPFEIFS 240
PRK14271 PRK14271
phosphate ABC transporter ATP-binding protein; Provisional
 8-235 2.54e-32

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172759 [Multi-domain]  Cd Length: 276  Bit Score: 122.13  E-value: 2.54e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   8 NLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRM-------IAGFETpdNGSIEIDGKDVVNLR---PNQRNI 77
Cdd:PRK14271  26 NLTLGFAGKTVLDQVSMGFPARAVTSLMGPTGSGKTTFLRTlnrmndkVSGYRY--SGDVLLGGRSIFNYRdvlEFRRRV 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  78 GMVFQAYALFPnMTVAQNVSFGLRVSG-KSRSEIDATVKEMLSLIRL-DHLADRY---PYQMSGGQQQRVALARALATKP 152
Cdd:PRK14271 104 GMLFQRPNPFP-MSIMDNVLAGVRAHKlVPRKEFRGVAQARLTEVGLwDAVKDRLsdsPFRLSGGQQQLLCLARTLAVNP 182

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 153 QVLLLDEPLSALDAKIRISLREEIRAIQQKLgiTTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNRP----ASR 228
Cdd:PRK14271 183 EVLLLDEPTSALDPTTTEKIEEFIRSLADRL--TVIIVTHNLAQAARISDRAALFFDGRLVEEGPTEQLFSSPkhaeTAR 260


                 ....*..
gi 559158796 229 FVASFVG 235
Cdd:PRK14271 261 YVAGLSG 267
CydD TIGR02857
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ...
 14-207 3.57e-32

thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD


Pssm-ID: 274323 [Multi-domain]  Cd Length: 529  Bit Score: 126.25  E-value: 3.57e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   14 GTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPN--QRNIGMVFQAYALFPNmT 91
Cdd:TIGR02857 333 GRRPALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEGSIAVNGVPLADADADswRDQIAWVPQHPFLFAG-T 411

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   92 VAQNVSFGLRvsGKSRSEIDATVK-----EMLSLIR--LDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSAL 164
Cdd:TIGR02857 412 IAENIRLARP--DASDAEIREALEragldEFVAALPqgLDTPIGEGGAGLSGGQAQRLALARAFLRDAPLLLLDEPTAHL 489

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 559158796  165 DAKIRISLREEIRAIQQklGITTVFVTHDqEEALSISDRIVVM 207
Cdd:TIGR02857 490 DAETEAEVLEALRALAQ--GRTVLLVTHR-LALAALADRIVVL 529
type_I_sec_PrtD TIGR01842
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in ...
 14-211 4.56e-32

type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 200134 [Multi-domain]  Cd Length: 544  Bit Score: 125.92  E-value: 4.56e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   14 GTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQ--RNIGMVFQAYALFPNmT 91
Cdd:TIGR01842 329 GKKPTLRGISFSLQAGEALAIIGPSGSGKSTLARLIVGIWPPTSGSVRLDGADLKQWDRETfgKHIGYLPQDVELFPG-T 407

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   92 VAQNVS-FGLRVSgkSRSEIDAT----VKEMLslIRLDHLADRY----PYQMSGGQQQRVALARALATKPQVLLLDEPLS 162
Cdd:TIGR01842 408 VAENIArFGENAD--PEKIIEAAklagVHELI--LRLPDGYDTVigpgGATLSGGQRQRIALARALYGDPKLVVLDEPNS 483

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 559158796  163 ALDAKIRISLREEIRAIQQKlGITTVFVTHdQEEALSISDRIVVMHEGR 211
Cdd:TIGR01842 484 NLDEEGEQALANAIKALKAR-GITVVVITH-RPSLLGCVDKILVLQDGR 530
PRK10247 PRK10247
putative ABC transporter ATP-binding protein YbbL; Provisional
 2-214 5.12e-32

putative ABC transporter ATP-binding protein YbbL; Provisional


Pssm-ID: 182331 [Multi-domain]  Cd Length: 225  Bit Score: 119.82  E-value: 5.12e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   2 AFLNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQ--RNIGM 79
Cdd:PRK10247   6 PLLQLQNVGYLAGDAKILNNISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTLLFEGEDISTLKPEIyrQQVSY 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  80 VFQAYALFPNmTVAQNVSFGLRVSGKsRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDE 159
Cdd:PRK10247  86 CAQTPTLFGD-TVYDNLIFPWQIRNQ-QPDPAIFLDDLERFALPDTILTKNIAELSGGEKQRISLIRNLQFMPKVLLLDE 163

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 559158796 160 PLSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEaLSISDRIVVM--HEGRADQ 214
Cdd:PRK10247 164 ITSALDESNKHNVNEIIHRYVREQNIAVLWVTHDKDE-INHADKVITLqpHAGEMQE 219
COG4586 COG4586
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 19-211 1.05e-31

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443643 [Multi-domain]  Cd Length: 323  Bit Score: 121.35  E-value: 1.05e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  19 VHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRP-NQRNIGMVF-QAYALFPNMTVAQnv 96
Cdd:COG4586   38 VDDISFTIEPGEIVGFIGPNGAGKSTTIKMLTGILVPTSGEVRVLGYVPFKRRKeFARRIGVVFgQRSQLWWDLPAID-- 115

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  97 SFGL--RVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSALDAKIRISLRE 174
Cdd:COG4586  116 SFRLlkAIYRIPDAEYKKRLDELVELLDLGELLDTPVRQLSLGQRMRCELAAALLHRPKILFLDEPTIGLDVVSKEAIRE 195

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 559158796 175 EIRAIQQKLGITTVFVTHDQE--EALsiSDRIVVMHEGR 211
Cdd:COG4586  196 FLKEYNRERGTTILLTSHDMDdiEAL--CDRVIVIDHGR 232
TagH COG1134
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ...
 10-224 1.17e-31

ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440749 [Multi-domain]  Cd Length: 245  Bit Score: 119.42  E-value: 1.17e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  10 KKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKdVVNLrpnqRNIGMVFQayalfPN 89
Cdd:COG1134   33 RTRREEFWALKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTSGRVEVNGR-VSAL----LELGAGFH-----PE 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  90 MTVAQNVSFGLRVSGKSRSEIDAtvkemlsliRLDHLAD-------------RYpyqmSGGQQQRVALARALATKPQVLL 156
Cdd:COG1134  103 LTGRENIYLNGRLLGLSRKEIDE---------KFDEIVEfaelgdfidqpvkTY----SSGMRARLAFAVATAVDPDILL 169

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 559158796 157 LDEPLSALDAKIRISLREEIRAIQQKlGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNR 224
Cdd:COG1134  170 VDEVLAVGDAAFQKKCLARIRELRES-GRTVIFVSHSMGAVRRLCDRAIWLEKGRLVMDGDPEEVIAA 236
ABCC_Glucan_exporter_like cd03254
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ...
 18-218 1.68e-31

ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213221 [Multi-domain]  Cd Length: 229  Bit Score: 118.48  E-value: 1.68e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  18 VVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDV--VNLRPNQRNIGMVFQAYALFPNmTVAQN 95
Cdd:cd03254   18 VLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQILIDGIDIrdISRKSLRSMIGVVLQDTFLFSG-TIMEN 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  96 VSFGLRVSGKSRSEIDATVKEMLSLIRldHLADRYPYQM-------SGGQQQRVALARALATKPQVLLLDEPLSALDAKI 168
Cdd:cd03254   97 IRLGRPNATDEEVIEAAKEAGAHDFIM--KLPNGYDTVLgenggnlSQGERQLLAIARAMLRDPKILILDEATSNIDTET 174

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 559158796 169 RISLREEIRAIQQklGITTVFVTHdqeeALSI---SDRIVVMHEGRADQIGSP 218
Cdd:cd03254  175 EKLIQEALEKLMK--GRTSIIIAH----RLSTiknADKILVLDDGKIIEEGTH 221
PRK13651 PRK13651
cobalt transporter ATP-binding subunit; Provisional
 6-223 1.87e-31

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184210 [Multi-domain]  Cd Length: 305  Bit Score: 120.19  E-value: 1.87e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   6 IKNLKKSFGTNT-----VVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKD-------------- 66
Cdd:PRK13651   5 VKNIVKIFNKKLptelkALDNVSVEINQGEFIAIIGQTGSGKTTFIEHLNALLLPDTGTIEWIFKDeknkkktkekekvl 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  67 ------------VVNLRPNQRNIGMVFQ--AYALFPNmTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLD-HLADRYP 131
Cdd:PRK13651  85 eklviqktrfkkIKKIKEIRRRVGVVFQfaEYQLFEQ-TIEKDIIFGPVSMGVSKEEAKKRAAKYIELVGLDeSYLQRSP 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 132 YQMSGGQQQRVALARALATKPQVLLLDEPLSALDAKIRIslreEIRAIQQKL---GITTVFVTHDQEEALSISDRIVVMH 208
Cdd:PRK13651 164 FELSGGQKRRVALAGILAMEPDFLVFDEPTAGLDPQGVK----EILEIFDNLnkqGKTIILVTHDLDNVLEWTKRTIFFK 239

                        250
                 ....*....|....*
gi 559158796 209 EGRADQIGSPFDIYN 223
Cdd:PRK13651 240 DGKIIKDGDTYDILS 254
cbiO PRK13646
energy-coupling factor transporter ATPase;
19-223 4.68e-31

energy-coupling factor transporter ATPase;


Pssm-ID: 184205 [Multi-domain]  Cd Length: 286  Bit Score: 118.73  E-value: 4.68e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  19 VHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVN------LRPNQRNIGMVFQayalFPNM-- 90
Cdd:PRK13646  23 IHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDITITHktkdkyIRPVRKRIGMVFQ----FPESql 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  91 ---TVAQNVSFGLRVSGKSRSEI-DATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSALDA 166
Cdd:PRK13646  99 fedTVEREIIFGPKNFKMNLDEVkNYAHRLLMDLGFSRDVMSQSPFQMSGGQMRKIAIVSILAMNPDIIVLDEPTAGLDP 178

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 559158796 167 KIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYN 223
Cdd:PRK13646 179 QSKRQVMRLLKSLQTDENKTIILVSHDMNEVARYADEVIVMKEGSIVSQTSPKELFK 235
PRK10584 PRK10584
putative ABC transporter ATP-binding protein YbbA; Provisional
 4-197 6.18e-31

putative ABC transporter ATP-binding protein YbbA; Provisional


Pssm-ID: 182569 [Multi-domain]  Cd Length: 228  Bit Score: 116.80  E-value: 6.18e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTN----TVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQR---- 75
Cdd:PRK10584   7 VEVHHLKKSVGQGehelSILTGVELVVKRGETIALIGESGSGKSTLLAILAGLDDGSSGEVSLVGQPLHQMDEEARaklr 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  76 --NIGMVFQAYALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLI----RLDHLadryPYQMSGGQQQRVALARALA 149
Cdd:PRK10584  87 akHVGFVFQSFMLIPTLNALENVELPALLRGESSRQSRNGAKALLEQLglgkRLDHL----PAQLSGGEQQRVALARAFN 162

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 559158796 150 TKPQVLLLDEPLSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEA 197
Cdd:PRK10584 163 GRPDVLFADEPTGNLDRQTGDKIADLLFSLNREHGTTLILVTHDLQLA 210
cbiO PRK13636
cobalt transporter ATP-binding subunit; Provisional
 21-222 7.94e-31

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184196 [Multi-domain]  Cd Length: 283  Bit Score: 118.03  E-value: 7.94e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  21 DFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDV-------VNLRpnqRNIGMVFQA--YALFpNMT 91
Cdd:PRK13636  24 GININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRILFDGKPIdysrkglMKLR---ESVGMVFQDpdNQLF-SAS 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  92 VAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSALDAKIRIS 171
Cdd:PRK13636 100 VYQDVSFGAVNLKLPEDEVRKRVDNALKRTGIEHLKDKPTHCLSFGQKKRVAIAGVLVMEPKVLVLDEPTAGLDPMGVSE 179

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 559158796 172 LREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIY 222
Cdd:PRK13636 180 IMKLLVEMQKELGLTIIIATHDIDIVPLYCDNVFVMKEGRVILQGNPKEVF 230
PRK14246 PRK14246
phosphate ABC transporter ATP-binding protein; Provisional
 4-234 1.08e-30

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172734 [Multi-domain]  Cd Length: 257  Bit Score: 117.07  E-value: 1.08e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGK-----------DVVNLRp 72
Cdd:PRK14246  11 FNISRLYLYINDKAILKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLIEIYDSKIKVDGKvlyfgkdifqiDAIKLR- 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  73 nqRNIGMVFQAYALFPNMTVAQNVSFGLRVSG-KSRSEIDATVKEMLSLIRL-DHLADRY---PYQMSGGQQQRVALARA 147
Cdd:PRK14246  90 --KEVGMVFQQPNPFPHLSIYDNIAYPLKSHGiKEKREIKKIVEECLRKVGLwKEVYDRLnspASQLSGGQQQRLTIARA 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 148 LATKPQVLLLDEPLSALDAKIRISLREEIRAIQQKlgITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNRPAS 227
Cdd:PRK14246 168 LALKPKVLLMDEPTSMIDIVNSQAIEKLITELKNE--IAIVIVSHNPQQVARVADYVAFLYNGELVEWGSSNEIFTSPKN 245


                 ....*..
gi 559158796 228 RFVASFV 234
Cdd:PRK14246 246 ELTEKYV 252
ABC_NatA_like cd03267
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ...
 17-211 1.17e-30

ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.


Pssm-ID: 213234 [Multi-domain]  Cd Length: 236  Bit Score: 116.28  E-value: 1.17e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  17 TVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPN-QRNIGMVF-QAYALFPNMTVAQ 94
Cdd:cd03267   35 EALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVRVAGLVPWKRRKKfLRRIGVVFgQKTQLWWDLPVID 114

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  95 NVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSALDAKIRISLRE 174
Cdd:cd03267  115 SFYLLAAIYDLPPARFKKRLDELSELLDLEELLDTPVRQLSLGQRMRAEIAAALLHEPEILFLDEPTIGLDVVAQENIRN 194

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 559158796 175 EIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGR 211
Cdd:cd03267  195 FLKEYNRERGTTVLLTSHYMKDIEALARRVLVIDKGR 231
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
 9-229 1.19e-30

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 121.74  E-value: 1.19e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   9 LKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTT----VLRMIAGfetpdNGSIEIDGKDVVNLRPNQ-----RNIGM 79
Cdd:PRK15134 292 LKRTVDHNVVVKNISFTLRPGETLGLVGESGSGKSTtglaLLRLINS-----QGEIWFDGQPLHNLNRRQllpvrHRIQV 366

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  80 VFQ--AYALFPNMTVAQNVSFGLRVSGK--SRSEIDATVKEMLSLIRLD-HLADRYPYQMSGGQQQRVALARALATKPQV 154
Cdd:PRK15134 367 VFQdpNSSLNPRLNVLQIIEEGLRVHQPtlSAAQREQQVIAVMEEVGLDpETRHRYPAEFSGGQRQRIAIARALILKPSL 446

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 559158796 155 LLLDEPLSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNRPASRF 229
Cdd:PRK15134 447 IILDEPTSSLDKTVQAQILALLKSLQQKHQLAYLFISHDLHVVRALCHQVIVLRQGEVVEQGDCERVFAAPQQEY 521
type_I_sec_LssB TIGR03375
type I secretion system ATPase, LssB family; Type I protein secretion is a system in some ...
 18-213 1.21e-30

type I secretion system ATPase, LssB family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. This model is related to models TIGR01842 and TIGR01846, and to bacteriocin ABC transporters that cleave their substrates during export. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]


Pssm-ID: 274550 [Multi-domain]  Cd Length: 694  Bit Score: 122.67  E-value: 1.21e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   18 VVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPN--QRNIGMVFQAYALFpNMTVAQN 95
Cdd:TIGR03375 480 ALDNVSLTIRPGEKVAIIGRIGSGKSTLLKLLLGLYQPTEGSVLLDGVDIRQIDPAdlRRNIGYVPQDPRLF-YGTLRDN 558

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   96 VSFGlrvsgkSRSEIDATVKEMLSLIRLDHLADRYP--YQM---------SGGQQQRVALARALATKPQVLLLDEPLSAL 164
Cdd:TIGR03375 559 IALG------APYADDEEILRAAELAGVTEFVRRHPdgLDMqigergrslSGGQRQAVALARALLRDPPILLLDEPTSAM 632

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 559158796  165 DAKiriSLREEIRAIQQKL-GITTVFVTHDQeEALSISDRIVVMHEGR--AD 213
Cdd:TIGR03375 633 DNR---SEERFKDRLKRWLaGKTLVLVTHRT-SLLDLVDRIIVMDNGRivAD 680
cbiO PRK13644
energy-coupling factor transporter ATPase;
4-250 4.30e-30

energy-coupling factor transporter ATPase;


Pssm-ID: 106587 [Multi-domain]  Cd Length: 274  Bit Score: 115.85  E-value: 4.30e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNT-VVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVN---LRPNQRNIGM 79
Cdd:PRK13644   2 IRLENVSYSYPDGTpALENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLVSGIDTGDfskLQGIRKLVGI 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  80 VFQ-AYALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLD 158
Cdd:PRK13644  82 VFQnPETQFVGRTVEEDLAFGPENLCLPPIEIRKRVDRALAEIGLEKYRHRSPKTLSGGQGQCVALAGILTMEPECLIFD 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 159 EPLSALDAKIRISLREEIRAIQQKlGITTVFVTHDQEEaLSISDRIVVMHEGRADQIGSPFDIYNRPASRfvasfvgTLN 238
Cdd:PRK13644 162 EVTSMLDPDSGIAVLERIKKLHEK-GKTIVYITHNLEE-LHDADRIIVMDRGKIVLEGEPENVLSDVSLQ-------TLG 232

                        250
                 ....*....|..
gi 559158796 239 MLEASVSEPAQN 250
Cdd:PRK13644 233 LTPPSLIELAEN 244
ABCC_Hemolysin cd03252
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ...
 18-217 4.69e-30

ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.


Pssm-ID: 213219 [Multi-domain]  Cd Length: 237  Bit Score: 114.89  E-value: 4.69e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  18 VVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPN--QRNIGMVFQAYALFpNMTVAQN 95
Cdd:cd03252   17 ILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLVDGHDLALADPAwlRRQVGVVLQENVLF-NRSIRDN 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  96 VSFGlrVSGKSRSEIDATVK-----EMLSLIRL--DHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSALDAki 168
Cdd:cd03252   96 IALA--DPGMSMERVIEAAKlagahDFISELPEgyDTIVGEQGAGLSGGQRQRIAIARALIHNPRILIFDEATSALDY-- 171

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 559158796 169 rislrEEIRAIQQKL-----GITTVFVTHdQEEALSISDRIVVMHEGRADQIGS 217
Cdd:cd03252  172 -----ESEHAIMRNMhdicaGRTVIIIAH-RLSTVKNADRIIVMEKGRIVEQGS 219
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
 4-221 5.44e-30

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 119.91  E-value: 5.44e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796    4 LNIKNLKKSF-----GTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEI----DGKDVVNLRPNQ 74
Cdd:TIGR03269 280 IKVRNVSKRYisvdrGVVKAVDNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGEVNVrvgdEWVDMTKPGPDG 359

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   75 RN-----IGMVFQAYALFPNMTVAQNV--SFGLrvsgksrsEIDATVKEMLSLIRL----------DHLADRYPYQMSGG 137
Cdd:TIGR03269 360 RGrakryIGILHQEYDLYPHRTVLDNLteAIGL--------ELPDELARMKAVITLkmvgfdeekaEEILDKYPDELSEG 431

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  138 QQQRVALARALATKPQVLLLDEPLSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGS 217
Cdd:TIGR03269 432 ERHRVALAQVLIKEPRIVILDEPTGTMDPITKVDVTHSILKAREEMEQTFIIVSHDMDFVLDVCDRAALMRDGKIVKIGD 511


                  ....
gi 559158796  218 PFDI 221
Cdd:TIGR03269 512 PEEI 515
PRK15112 PRK15112
peptide ABC transporter ATP-binding protein SapF;
4-235 7.47e-30

peptide ABC transporter ATP-binding protein SapF;


Pssm-ID: 185067 [Multi-domain]  Cd Length: 267  Bit Score: 115.27  E-value: 7.47e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNT---------VVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVV--NLRP 72
Cdd:PRK15112   5 LEVRNLSKTFRYRTgwfrrqtveAVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELLIDDHPLHfgDYSY 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  73 NQRNIGMVFQ--AYALFPNMTVAQNVSFGLRV----SGKSRSE-IDATVKeMLSLIRlDHlADRYPYQMSGGQQQRVALA 145
Cdd:PRK15112  85 RSQRIRMIFQdpSTSLNPRQRISQILDFPLRLntdlEPEQREKqIIETLR-QVGLLP-DH-ASYYPHMLAPGQKQRLGLA 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 146 RALATKPQVLLLDEPLSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNRP 225
Cdd:PRK15112 162 RALILRPKVIIADEALASLDMSMRSQLINLMLELQEKQGISYIYVTQHLGMMKHISDQVLVMHQGEVVERGSTADVLASP 241

                        250
                 ....*....|....
gi 559158796 226 ----ASRFVASFVG 235
Cdd:PRK15112 242 lhelTKRLIAGHFG 255
cbiO PRK13631
cobalt transporter ATP-binding subunit; Provisional
 4-226 1.82e-29

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237451 [Multi-domain]  Cd Length: 320  Bit Score: 115.33  E-value: 1.82e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNT-----VVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIdgKDVVN--------- 69
Cdd:PRK13631  22 LRVKNLYCVFDEKQenelvALNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLIKSKYGTIQV--GDIYIgdkknnhel 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  70 -LRPNQRNI----------GMVFQ--AYALFPNmTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDH-LADRYPYQMS 135
Cdd:PRK13631 100 iTNPYSKKIknfkelrrrvSMVFQfpEYQLFKD-TIEKDIMFGPVALGVKKSEAKKLAKFYLNKMGLDDsYLERSPFGLS 178

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 136 GGQQQRVALARALATKPQVLLLDEPLSALDAKiriSLREEIRAIQ--QKLGITTVFVTHDQEEALSISDRIVVMHEGRAD 213
Cdd:PRK13631 179 GGQKRRVAIAGILAIQPEILIFDEPTAGLDPK---GEHEMMQLILdaKANNKTVFVITHTMEHVLEVADEVIVMDKGKIL 255

                        250
                 ....*....|...
gi 559158796 214 QIGSPFDIYNRPA 226
Cdd:PRK13631 256 KTGTPYEIFTDQH 268
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
 4-242 2.85e-29

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 118.42  E-value: 2.85e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSF----GTNTVVHDFNLAVGKGEFVSFLGPSGCGKT-TVLRMIAGFETPdNGSIEIDG-------KDVVNLR 71
Cdd:PRK10261  13 LAVENLNIAFmqeqQKIAAVRNLSFSLQRGETLAIVGESGSGKSvTALALMRLLEQA-GGLVQCDKmllrrrsRQVIELS 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  72 PNQR---------NIGMVFQA--YALFPNMTVAQNVSFGLRV-SGKSRSEIDATVKEMLSLIRL---DHLADRYPYQMSG 136
Cdd:PRK10261  92 EQSAaqmrhvrgaDMAMIFQEpmTSLNPVFTVGEQIAESIRLhQGASREEAMVEAKRMLDQVRIpeaQTILSRYPHQLSG 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 137 GQQQRVALARALATKPQVLLLDEPLSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIG 216
Cdd:PRK10261 172 GMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQKEMSMGVIFITHDMGVVAEIADRVLVMYQGEAVETG 251

                        250       260
                 ....*....|....*....|....*.
gi 559158796 217 SPFDIYNRPASRFVASFVGTLNMLEA 242
Cdd:PRK10261 252 SVEQIFHAPQHPYTRALLAAVPQLGA 277
PRK10253 PRK10253
iron-enterobactin ABC transporter ATP-binding protein;
7-221 3.18e-29

iron-enterobactin ABC transporter ATP-binding protein;


Pssm-ID: 182336 [Multi-domain]  Cd Length: 265  Bit Score: 113.54  E-value: 3.18e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   7 KNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQ--RNIGMVFQAY 84
Cdd:PRK10253  11 EQLTLGYGKYTVAENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLDGEHIQHYASKEvaRRIGLLAQNA 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  85 ALFPNMTVAQNVSFGLR----VSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEP 160
Cdd:PRK10253  91 TTPGDITVQELVARGRYphqpLFTRWRKEDEEAVTKAMQATGITHLADQSVDTLSGGQRQRAWIAMVLAQETAIMLLDEP 170

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 559158796 161 LSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDI 221
Cdd:PRK10253 171 TTWLDISHQIDLLELLSELNREKGYTLAAVLHDLNQACRYASHLIALREGKIVAQGAPKEI 231
cbiO PRK13641
energy-coupling factor transporter ATPase;
21-225 3.22e-29

energy-coupling factor transporter ATPase;


Pssm-ID: 237456 [Multi-domain]  Cd Length: 287  Bit Score: 113.77  E-value: 3.22e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  21 DFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVV------NLRPNQRNIGMVFQ--AYALFPNmTV 92
Cdd:PRK13641  25 NISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIAGYHITpetgnkNLKKLRKKVSLVFQfpEAQLFEN-TV 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  93 AQNVSFGLRVSGKSRSEIDATVKEMLSLIRL-DHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSALDAKIRIS 171
Cdd:PRK13641 104 LKDVEFGPKNFGFSEDEAKEKALKWLKKVGLsEDLISKSPFELSGGQMRRVAIAGVMAYEPEILCLDEPAAGLDPEGRKE 183

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 559158796 172 LReEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNRP 225
Cdd:PRK13641 184 MM-QLFKDYQKAGHTVILVTHNMDDVAEYADDVLVLEHGKLIKHASPKEIFSDK 236
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
 4-210 3.48e-29

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 117.46  E-value: 3.48e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPN---QRNIGMV 80
Cdd:PRK15439  12 LCARSISKQYSGVEVLKGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGTLEIGGNPCARLTPAkahQLGIYLV 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  81 FQAYALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADrypyQMSGGQQQRVALARALATKPQVLLLDEP 160
Cdd:PRK15439  92 PQEPLLFPNLSVKENILFGLPKRQASMQKMKQLLAALGCQLDLDSSAG----SLEVADRQIVEILRGLMRDSRILILDEP 167

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 559158796 161 LSALDAKIRISLREEIRAIQQKlGITTVFVTHDQEEALSISDRIVVMHEG 210
Cdd:PRK15439 168 TASLTPAETERLFSRIRELLAQ-GVGIVFISHKLPEIRQLADRISVMRDG 216
oppD PRK09473
oligopeptide transporter ATP-binding component; Provisional
 1-226 1.62e-28

oligopeptide transporter ATP-binding component; Provisional


Pssm-ID: 181888 [Multi-domain]  Cd Length: 330  Bit Score: 112.90  E-value: 1.62e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   1 MAFLNIKNLKKSFGTN----TVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPD---NGSIEIDGKDVVNLRPN 73
Cdd:PRK09473  10 DALLDVKDLRVTFSTPdgdvTAVNDLNFSLRAGETLGIVGESGSGKSQTAFALMGLLAANgriGGSATFNGREILNLPEK 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  74 QRN------IGMVFQ--AYALFPNMTVAQNVSFGLRV-SGKSRSE-IDATVKeMLSLIRLDHLADR---YPYQMSGGQQQ 140
Cdd:PRK09473  90 ELNklraeqISMIFQdpMTSLNPYMRVGEQLMEVLMLhKGMSKAEaFEESVR-MLDAVKMPEARKRmkmYPHEFSGGMRQ 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 141 RVALARALATKPQVLLLDEPLSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFD 220
Cdd:PRK09473 169 RVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGNARD 248


                 ....*.
gi 559158796 221 IYNRPA 226
Cdd:PRK09473 249 VFYQPS 254
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
12-207 1.86e-28

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 109.25  E-value: 1.86e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  12 SFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQRNIGmvfqayALFPnMT 91
Cdd:NF040873   1 GYGGRPVLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTVRRAGGARVAYVPQRSEVP------DSLP-LT 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  92 VAQNVSFGL----RVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSALDAK 167
Cdd:NF040873  74 VRDLVAMGRwarrGLWRRLTRDDRAAVDDALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLLLDEPTTGLDAE 153

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 559158796 168 IRISLREEIRAIQQKlGITTVFVTHDQEEALSIsDRIVVM 207
Cdd:NF040873 154 SRERIIALLAEEHAR-GATVVVVTHDLELVRRA-DPCVLL 191
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
 29-225 2.63e-28

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 115.72  E-value: 2.63e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  29 GEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQ-----RNIGMVFQ-AYA-LFPNMTVAQNVSFGLR 101
Cdd:PRK10261 350 GETLSLVGESGSGKSTTGRALLRLVESQGGEIIFNGQRIDTLSPGKlqalrRDIQFIFQdPYAsLDPRQTVGDSIMEPLR 429

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 102 VSGKSRSEIDAT-VKEMLSLIRL--DHlADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSALDAKIRISLREEIRA 178
Cdd:PRK10261 430 VHGLLPGKAAAArVAWLLERVGLlpEH-AWRYPHEFSGGQRQRICIARALALNPKVIIADEAVSALDVSIRGQIINLLLD 508

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 559158796 179 IQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNRP 225
Cdd:PRK10261 509 LQRDFGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGPRRAVFENP 555
ccmA TIGR01189
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ...
 21-192 3.82e-28

heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]


Pssm-ID: 273491 [Multi-domain]  Cd Length: 198  Bit Score: 108.60  E-value: 3.82e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   21 DFNLAvgKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPN-QRNIGMVFQAYALFPNMTVAQNVSFG 99
Cdd:TIGR01189  20 SFTLN--AGEALQVTGPNGIGKTTLLRILAGLLRPDSGEVRWNGTPLAEQRDEpHENILYLGHLPGLKPELSALENLHFW 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  100 LRVSGKSrseiDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSALDAKIRISLREEIRAI 179
Cdd:TIGR01189  98 AAIHGGA----QRTIEDALAAVGLTGFEDLPAAQLSAGQQRRLALARLWLSRRPLWILDEPTTALDKAGVALLAGLLRAH 173

                         170
                  ....*....|...
gi 559158796  180 QQKLGItTVFVTH 192
Cdd:TIGR01189 174 LARGGI-VLLTTH 185
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
 6-242 6.15e-28

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 115.50  E-value: 6.15e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796     6 IKNLKKSFGT--NTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDV-VNLRPNQRNIGMVFQ 82
Cdd:TIGR01257  931 VKNLVKIFEPsgRPAVDRLNITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGKDIeTNLDAVRQSLGMCPQ 1010

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796    83 AYALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLS 162
Cdd:TIGR01257 1011 HNILFHHLTVAEHILFYAQLKGRSWEEAQLEMEAMLEDTGLHHKRNEEAQDLSGGMQRKLSVAIAFVGDAKVVVLDEPTS 1090

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   163 ALDAKIRISLREEIraIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNRPASRFVASFVGTLNMLEA 242
Cdd:TIGR01257 1091 GVDPYSRRSIWDLL--LKYRSGRTIIMSTHHMDEADLLGDRIAIISQGRLYCSGTPLFLKNCFGTGFYLTLVRKMKNIQS 1168
ABCG_EPDR cd03213
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ...
 17-211 7.49e-28

Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.


Pssm-ID: 213180 [Multi-domain]  Cd Length: 194  Bit Score: 107.64  E-value: 7.49e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  17 TVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAG--FETPDNGSIEIDGKDVVNLRPNQRnIGMVFQAYALFPNMTVAQ 94
Cdd:cd03213   23 QLLKNVSGKAKPGELTAIMGPSGAGKSTLLNALAGrrTGLGVSGEVLINGRPLDKRSFRKI-IGYVPQDDILHPTLTVRE 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  95 NVSFGLRVSGksrseidatvkemlslirldhladrypyqMSGGQQQRVALARALATKPQVLLLDEPLSALDAKIRISLRE 174
Cdd:cd03213  102 TLMFAAKLRG-----------------------------LSGGERKRVSIALELVSNPSLLFLDEPTSGLDSSSALQVMS 152

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 559158796 175 EIRAIQQkLGITTVFVTHD-QEEALSISDRIVVMHEGR 211
Cdd:cd03213  153 LLRRLAD-TGRTIICSIHQpSSEIFELFDKLLLLSQGR 189
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
 6-193 8.78e-28

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 113.62  E-value: 8.78e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   6 IKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGkdvvNLRpnqrnIGMVFQAYA 85
Cdd:COG0488    1 LENLSKSFGGRPLLDDVSLSINPGDRIGLVGRNGAGKSTLLKILAGELEPDSGEVSIPK----GLR-----IGYLPQEPP 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  86 LFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLS----LIRLDHLADRY------------------------PYQ---- 133
Cdd:COG0488   72 LDDDLTVLDTVLDGDAELRALEAELEELEAKLAEpdedLERLAELQEEFealggweaearaeeilsglgfpeeDLDrpvs 151

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 559158796 134 -MSGGQQQRVALARALATKPQVLLLDEPLSALDAKIRISLREEIRAIQqklgITTVFVTHD 193
Cdd:COG0488  152 eLSGGWRRRVALARALLSEPDLLLLDEPTNHLDLESIEWLEEFLKNYP----GTVLVVSHD 208
ABCF_EF-3 cd03221
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ...
 4-211 6.86e-27

ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.


Pssm-ID: 213188 [Multi-domain]  Cd Length: 144  Bit Score: 103.68  E-value: 6.86e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIeidgkdvvnlrpnqrnigmvfqa 83
Cdd:cd03221    1 IELENLSKTYGGKLLLKDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEGIV----------------------- 57

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  84 yalfpnmTVAQNVSFGlrvsgksrseidatvkemlslirldHLAdrypyQMSGGQQQRVALARALATKPQVLLLDEPLSA 163
Cdd:cd03221   58 -------TWGSTVKIG-------------------------YFE-----QLSGGEKMRLALAKLLLENPNLLLLDEPTNH 100

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 559158796 164 LDAKIRISLREEIRAIQQklgiTTVFVTHDQEEALSISDRIVVMHEGR 211
Cdd:cd03221  101 LDLESIEALEEALKEYPG----TVILVSHDRYFLDQVATKIIELEDGK 144
dppD PRK11022
dipeptide transporter ATP-binding subunit; Provisional
 1-225 8.70e-27

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 182906 [Multi-domain]  Cd Length: 326  Bit Score: 108.29  E-value: 8.70e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   1 MAFLNIKNLKKSFGTNTV----VHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGF-ETPDN---GSIEIDGKDVVNLRP 72
Cdd:PRK11022   1 MALLNVDKLSVHFGDESApfraVDRISYSVKQGEVVGIVGESGSGKSVSSLAIMGLiDYPGRvmaEKLEFNGQDLQRISE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  73 NQR------NIGMVFQ--AYALFPNMTVAQNVSFGLRV-SGKSRSEIDATVKEMLSLIRLDHLADR---YPYQMSGGQQQ 140
Cdd:PRK11022  81 KERrnlvgaEVAMIFQdpMTSLNPCYTVGFQIMEAIKVhQGGNKKTRRQRAIDLLNQVGIPDPASRldvYPHQLSGGMSQ 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 141 RVALARALATKPQVLLLDEPLSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFD 220
Cdd:PRK11022 161 RVMIAMAIACRPKLLIADEPTTALDVTIQAQIIELLLELQQKENMALVLITHDLALVAEAAHKIIVMYAGQVVETGKAHD 240


                 ....*
gi 559158796 221 IYNRP 225
Cdd:PRK11022 241 IFRAP 245
MsbA_lipidA TIGR02203
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide ...
 18-211 1.35e-26

lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide chain transporter in the ATP-binding cassette (ABC) transporter family, MsbA, which exports lipid A. It may also act in multidrug resistance. Lipid A, a part of lipopolysaccharide, is found in the outer leaflet of the outer membrane of most Gram-negative bacteria. Members of this family are restricted to the Proteobacteria (although lipid A is more broadly distributed) and often are clustered with lipid A biosynthesis genes. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]


Pssm-ID: 131258 [Multi-domain]  Cd Length: 571  Bit Score: 110.58  E-value: 1.35e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   18 VVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDV--VNLRPNQRNIGMVFQAYALFpNMTVAQN 95
Cdd:TIGR02203 347 ALDSISLVIEPGETVALVGRSGSGKSTLVNLIPRFYEPDSGQILLDGHDLadYTLASLRRQVALVSQDVVLF-NDTIANN 425

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   96 VSFGlRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQ-------MSGGQQQRVALARALATKPQVLLLDEPLSALDAki 168
Cdd:TIGR02203 426 IAYG-RTEQADRAEIERALAAAYAQDFVDKLPLGLDTPigengvlLSGGQRQRLAIARALLKDAPILILDEATSALDN-- 502

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 559158796  169 rislrEEIRAIQQKL-----GITTVFVTHdqeeALSI---SDRIVVMHEGR 211
Cdd:TIGR02203 503 -----ESERLVQAALerlmqGRTTLVIAH----RLSTiekADRIVVMDDGR 544
livF PRK11614
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
1-211 1.59e-26

high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;


Pssm-ID: 183231 [Multi-domain]  Cd Length: 237  Bit Score: 105.35  E-value: 1.59e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   1 MAFLNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVN---LRPNQRNI 77
Cdd:PRK11614   3 KVMLSFDKVSAHYGKIQALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVFDGKDITDwqtAKIMREAV 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  78 GMVFQAYALFPNMTVAQNVSFGLRVSgkSRSEIDATVKEMLSLI-RLDHLADRYPYQMSGGQQQRVALARALATKPQVLL 156
Cdd:PRK11614  83 AIVPEGRRVFSRMTVEENLAMGGFFA--ERDQFQERIKWVYELFpRLHERRIQRAGTMSGGEQQMLAIGRALMSQPRLLL 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 559158796 157 LDEPLSALDAKIRISLREEIRAIQQKlGITTVFVTHDQEEALSISDRIVVMHEGR 211
Cdd:PRK11614 161 LDEPSLGLAPIIIQQIFDTIEQLREQ-GMTIFLVEQNANQALKLADRGYVLENGH 214
ATM1 COG5265
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ...
 20-211 1.83e-26

ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444078 [Multi-domain]  Cd Length: 605  Bit Score: 110.29  E-value: 1.83e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  20 HDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDV--VNLRPNQRNIGMVFQAYALFpNMTVAQNVS 97
Cdd:COG5265  375 KGVSFEVPAGKTVAIVGPSGAGKSTLARLLFRFYDVTSGRILIDGQDIrdVTQASLRAAIGIVPQDTVLF-NDTIAYNIA 453

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  98 FGlrvsgksrsEIDATVKEMLSLIRLDHLAD---RYP--YQ---------MSGGQQQRVALARALATKPQVLLLDEPLSA 163
Cdd:COG5265  454 YG---------RPDASEEEVEAAARAAQIHDfieSLPdgYDtrvgerglkLSGGEKQRVAIARTLLKNPPILIFDEATSA 524

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 559158796 164 LDAkirislREEiRAIQQKL-----GITTVFVTHdqeeALSI---SDRIVVMHEGR 211
Cdd:COG5265  525 LDS------RTE-RAIQAALrevarGRTTLVIAH----RLSTivdADEILVLEAGR 569
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
 4-211 2.01e-26

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 109.77  E-value: 2.01e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIdGKDVvnlrpnqrNIGMVFQA 83
Cdd:COG0488  316 LELEGLSKSYGDKTLLDDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAGELEPDSGTVKL-GETV--------KIGYFDQH 386

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  84 YALF-PNMTVAQNVSfglRVS-GKSRSEIDATVKEML-------SLIRldhladrypyQMSGGQQQRVALARALATKPQV 154
Cdd:COG0488  387 QEELdPDKTVLDELR---DGApGGTEQEVRGYLGRFLfsgddafKPVG----------VLSGGEKARLALAKLLLSPPNV 453

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 559158796 155 LLLDEPLSALDAkirislrEEIRAIQQKL----GiTTVFVTHDQEEALSISDRIVVMHEGR 211
Cdd:COG0488  454 LLLDEPTNHLDI-------ETLEALEEALddfpG-TVLLVSHDRYFLDRVATRILEFEDGG 506
CP_lyasePhnK TIGR02323
phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P ...
 2-216 2.90e-26

phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P lyase systems for utilization of phosphonates. These systems resemble phosphonatase-based systems in having a three component ABC transporter, where TIGR01097 is the permease, TIGR01098 is the phosphonates binding protein, and TIGR02315 is the ATP-binding cassette (ABC) protein. They differ, however, in having, typically, ten or more additional genes, many of which are believed to form a membrane-associated complex. This protein (PhnK) and the adjacent-encoded PhnL resemble transporter ATP-binding proteins but are suggested, based on mutatgenesis studies, to be part of this complex rather than part of a transporter per se. [Central intermediary metabolism, Phosphorus compounds]


Pssm-ID: 188208 [Multi-domain]  Cd Length: 253  Bit Score: 105.30  E-value: 2.90e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796    2 AFLNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNL------RPNQR 75
Cdd:TIGR02323   2 PLLQVSGLSKSYGGGKGCRDVSFDLYPGEVLGIVGESGSGKSTLLGCLAGRLAPDHGTATYIMRSGAELelyqlsEAERR 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   76 NI-----GMVFQAYALFPNMTVAQNVSFGLR---VSGKSRSEIDATVKEMLSLIRLDH-LADRYPYQMSGGQQQRVALAR 146
Cdd:TIGR02323  82 RLmrtewGFVHQNPRDGLRMRVSAGANIGERlmaIGARHYGNIRATAQDWLEEVEIDPtRIDDLPRAFSGGMQQRLQIAR 161

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  147 ALATKPQVLLLDEPLSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIG 216
Cdd:TIGR02323 162 NLVTRPRLVFMDEPTGGLDVSVQARLLDLLRGLVRDLGLAVIIVTHDLGVARLLAQRLLVMQQGRVVESG 231
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
 4-211 3.33e-26

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 108.86  E-value: 3.33e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAG---FETPDnGSIEIDGKDVV--NLRPNQRN-I 77
Cdd:PRK13549   6 LEMKNITKTFGGVKALDNVSLKVRAGEIVSLCGENGAGKSTLMKVLSGvypHGTYE-GEIIFEGEELQasNIRDTERAgI 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  78 GMVFQAYALFPNMTVAQNVSFGLRVSGKSRSEIDATV---KEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQV 154
Cdd:PRK13549  85 AIIHQELALVKELSVLENIFLGNEITPGGIMDYDAMYlraQKLLAQLKLDINPATPVGNLGLGQQQLVEIAKALNKQARL 164

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 559158796 155 LLLDEPLSALDAK-IRIsLREEIRAIQQKlGITTVFVTHDQEEALSISDRIVVMHEGR 211
Cdd:PRK13549 165 LILDEPTASLTESeTAV-LLDIIRDLKAH-GIACIYISHKLNEVKAISDTICVIRDGR 220
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
 4-211 4.37e-26

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 108.58  E-value: 4.37e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLK-KSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQ-RNIGMVF 81
Cdd:COG3845  258 LEVENLSvRDDRGVPALKDVSLEVRAGEILGIAGVAGNGQSELAEALAGLRPPASGSIRLDGEDITGLSPRErRRLGVAY 337

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  82 -----QAYALFPNMTVAQNVSFGLRVSGK-------SRSEIDATVKEMLSL--IR---LDHLADrypyQMSGGQQQRVAL 144
Cdd:COG3845  338 ipedrLGRGLVPDMSVAENLILGRYRRPPfsrggflDRKAIRAFAEELIEEfdVRtpgPDTPAR----SLSGGNQQKVIL 413

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 559158796 145 ARALATKPQVLLLDEPLSALDAKIRISLREEIRAIQQKlGITTVFVTHDQEEALSISDRIVVMHEGR 211
Cdd:COG3845  414 ARELSRDPKLLIAAQPTRGLDVGAIEFIHQRLLELRDA-GAAVLLISEDLDEILALSDRIAVMYEGR 479
ABCC_cytochrome_bd cd03247
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ...
 4-211 5.10e-26

ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.


Pssm-ID: 213214 [Multi-domain]  Cd Length: 178  Bit Score: 102.39  E-value: 5.10e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTN--TVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQRN-IGMV 80
Cdd:cd03247    1 LSINNVSFSYPEQeqQVLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGEITLDGVPVSDLEKALSSlISVL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  81 FQAYALFpNMTVAQNVsfGLRvsgksrseidatvkemlslirldhladrypyqMSGGQQQRVALARALATKPQVLLLDEP 160
Cdd:cd03247   81 NQRPYLF-DTTLRNNL--GRR--------------------------------FSGGERQRLALARILLQDAPIVLLDEP 125

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 559158796 161 LSALDAKIRISLREEIraIQQKLGITTVFVTHdQEEALSISDRIVVMHEGR 211
Cdd:cd03247  126 TVGLDPITERQLLSLI--FEVLKDKTLIWITH-HLTGIEHMDKILFLENGK 173
PRK13657 PRK13657
glucan ABC transporter ATP-binding protein/ permease;
14-220 5.42e-26

glucan ABC transporter ATP-binding protein/ permease;


Pssm-ID: 184214 [Multi-domain]  Cd Length: 588  Bit Score: 108.90  E-value: 5.42e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  14 GTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDV--VNLRPNQRNIGMVFQAYALFpNMT 91
Cdd:PRK13657 346 NSRQGVEDVSFEAKPGQTVAIVGPTGAGKSTLINLLQRVFDPQSGRILIDGTDIrtVTRASLRRNIAVVFQDAGLF-NRS 424

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  92 VAQNvsfgLRVsGKSrseiDATVKEML--------------SLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLL 157
Cdd:PRK13657 425 IEDN----IRV-GRP----DATDEEMRaaaeraqahdfierKPDGYDTVVGERGRQLSGGERQRLAIARALLKDPPILIL 495

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 559158796 158 DEPLSALDAKIRISLREEIRAIQQklGITTVFVTHdqeeALSI---SDRIVVMHEGRADQIGSpFD 220
Cdd:PRK13657 496 DEATSALDVETEAKVKAALDELMK--GRTTFIIAH----RLSTvrnADRILVFDNGRVVESGS-FD 554
ABCC_MRP_domain1 cd03250
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ...
 10-211 5.57e-26

ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213217 [Multi-domain]  Cd Length: 204  Bit Score: 102.93  E-value: 5.57e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  10 KKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKdvvnlrpnqrnIGMVFQaYALFPN 89
Cdd:cd03250   12 SGEQETSFTLKDINLEVPKGELVAIVGPVGSGKSSLLSALLGELEKLSGSVSVPGS-----------IAYVSQ-EPWIQN 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  90 MTVAQNVSFGlrvsgksrSEIDA----TVKEMLSLIR-LDHLADRYPYQ-------MSGGQQQRVALARALATKPQVLLL 157
Cdd:cd03250   80 GTIRENILFG--------KPFDEeryeKVIKACALEPdLEILPDGDLTEigekginLSGGQKQRISLARAVYSDADIYLL 151

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 559158796 158 DEPLSALDAKIRISLREeiRAIQQKL--GITTVFVTHdQEEALSISDRIVVMHEGR 211
Cdd:cd03250  152 DDPLSAVDAHVGRHIFE--NCILGLLlnNKTRILVTH-QLQLLPHADQIVVLDNGR 204
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
 4-211 1.31e-25

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 107.22  E-value: 1.31e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796    4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPD--NGSIEIDGKDVV--NLRPNQR-NIG 78
Cdd:TIGR02633   2 LEMKGIVKTFGGVKALDGIDLEVRPGECVGLCGENGAGKSTLMKILSGVYPHGtwDGEIYWSGSPLKasNIRDTERaGIV 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   79 MVFQAYALFPNMTVAQNVSFGLRVSGK-SRSEIDATV---KEMLSLIRLDHLADRYPY-QMSGGQQQRVALARALATKPQ 153
Cdd:TIGR02633  82 IIHQELTLVPELSVAENIFLGNEITLPgGRMAYNAMYlraKNLLRELQLDADNVTRPVgDYGGGQQQLVEIAKALNKQAR 161

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 559158796  154 VLLLDEPLSALDAKIRISLREEIRAIQQKlGITTVFVTHDQEEALSISDRIVVMHEGR 211
Cdd:TIGR02633 162 LLILDEPSSSLTEKETEILLDIIRDLKAH-GVACVYISHKLNEVKAVCDTICVIRDGQ 218
SufC COG0396
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ...
 4-211 2.99e-25

Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440165 [Multi-domain]  Cd Length: 245  Bit Score: 102.07  E-value: 2.99e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFE--TPDNGSIEIDGKDVVNLRPNQR---NIG 78
Cdd:COG0396    1 LEIKNLHVSVEGKEILKGVNLTIKPGEVHAIMGPNGSGKSTLAKVLMGHPkyEVTSGSILLDGEDILELSPDERaraGIF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  79 MVFQAYALFPNMTVAQnvsFgLR--VSGKSRSEIDA-----TVKEMLSLIRLDH-LADRY-PYQMSGGQQQRVALARALA 149
Cdd:COG0396   81 LAFQYPVEIPGVSVSN---F-LRtaLNARRGEELSAreflkLLKEKMKELGLDEdFLDRYvNEGFSGGEKKRNEILQMLL 156

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 559158796 150 TKPQVLLLDEPLSALDA-KIRIsLREEIRAIQQKlGITTVFVTHdQEEALSI--SDRIVVMHEGR 211
Cdd:COG0396  157 LEPKLAILDETDSGLDIdALRI-VAEGVNKLRSP-DRGILIITH-YQRILDYikPDFVHVLVDGR 218
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
 1-280 3.43e-25

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 106.33  E-value: 3.43e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   1 MAFLNIKNLKKSF----GTNTVVHDFNLAVGKGEFVSFLGPSGCGKT-TVLRMIAGFETPD----NGSIEIDGKDVVN-- 69
Cdd:PRK15134   3 QPLLAIENLSVAFrqqqTVRTVVNDVSLQIEAGETLALVGESGSGKSvTALSILRLLPSPPvvypSGDIRFHGESLLHas 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  70 ------LRPNQrnIGMVFQA--YALFPNMTVAQNVSFGLRVSGKSRSEidATVKEMLSL-----IR--LDHLADrYPYQM 134
Cdd:PRK15134  83 eqtlrgVRGNK--IAMIFQEpmVSLNPLHTLEKQLYEVLSLHRGMRRE--AARGEILNCldrvgIRqaAKRLTD-YPHQL 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 135 SGGQQQRVALARALATKPQVLLLDEPLSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQ 214
Cdd:PRK15134 158 SGGERQRVMIAMALLTRPELLIADEPTTALDVSVQAQILQLLRELQQELNMGLLFITHNLSIVRKLADRVAVMQNGRCVE 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 215 IGSPFDIYNRPASRFvasfvgTLNMLEAS-----VSEPAQNSIDLDGRQITV---------QETLAHHPKGKPLTLALRP 280
Cdd:PRK15134 238 QNRAATLFSAPTHPY------TQKLLNSEpsgdpVPLPEPASPLLDVEQLQVafpirkgilKRTVDHNVVVKNISFTLRP 311
phnK PRK11701
phosphonate C-P lyase system protein PhnK; Provisional
 4-211 5.04e-25

phosphonate C-P lyase system protein PhnK; Provisional


Pssm-ID: 183280 [Multi-domain]  Cd Length: 258  Bit Score: 101.93  E-value: 5.04e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNL------RPNQRNI 77
Cdd:PRK11701   7 LSVRGLTKLYGPRKGCRDVSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDAGEVHYRMRDGQLRdlyalsEAERRRL 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  78 -----GMVFQ--AYALFPNMTVAQNVS-----FGLRVSGKSRS---------EIDATvkemlsliRLDHLadryPYQMSG 136
Cdd:PRK11701  87 lrtewGFVHQhpRDGLRMQVSAGGNIGerlmaVGARHYGDIRAtagdwlervEIDAA--------RIDDL----PTTFSG 154

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 559158796 137 GQQQRVALARALATKPQVLLLDEPLSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGR 211
Cdd:PRK11701 155 GMQQRLQIARNLVTHPRLVFMDEPTGGLDVSVQARLLDLLRGLVRELGLAVVIVTHDLAVARLLAHRLLVMKQGR 229
CydC TIGR02868
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ...
 14-193 8.26e-25

thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.


Pssm-ID: 274331 [Multi-domain]  Cd Length: 530  Bit Score: 105.14  E-value: 8.26e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   14 GTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQ--RNIGMVFQAYALFpNMT 91
Cdd:TIGR02868 346 GAPPVLDGVSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPLQGEVTLDGVPVSSLDQDEvrRRVSVCAQDAHLF-DTT 424

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   92 VAQNVSFGlrvsgksRSEI-DATVKEMLSLIRLDHLADRYPYQM-----------SGGQQQRVALARALATKPQVLLLDE 159
Cdd:TIGR02868 425 VRENLRLA-------RPDAtDEELWAALERVGLADWLRALPDGLdtvlgeggarlSGGERQRLALARALLADAPILLLDE 497

                         170       180       190
                  ....*....|....*....|....*....|....
gi 559158796  160 PLSALDAKIRISLREEIRAIQQklGITTVFVTHD 193
Cdd:TIGR02868 498 PTEHLDAETADELLEDLLAALS--GRTVVLITHH 529
YddA COG4178
ABC-type uncharacterized transport system, permease and ATPase components [General function ...
 17-192 1.05e-24

ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];


Pssm-ID: 443337 [Multi-domain]  Cd Length: 571  Bit Score: 104.89  E-value: 1.05e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  17 TVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEidgkdvvnlRPNQRNigMVF---QAYalFPNMTVA 93
Cdd:COG4178  377 PLLEDLSLSLKPGERLLITGPSGSGKSTLLRAIAGLWPYGSGRIA---------RPAGAR--VLFlpqRPY--LPLGTLR 443

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  94 QNVSFGLRVSGKSrseiDATVKEMLSLIRLDHLADRY------PYQMSGGQQQRVALARALATKPQVLLLDEPLSALDAK 167
Cdd:COG4178  444 EALLYPATAEAFS----DAELREALEAVGLGHLAERLdeeadwDQVLSLGEQQRLAFARLLLHKPDWLFLDEATSALDEE 519

                        170       180
                 ....*....|....*....|....*.
gi 559158796 168 IRISLreeIRAIQQKL-GITTVFVTH 192
Cdd:COG4178  520 NEAAL---YQLLREELpGTTVISVGH 542
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
 4-262 3.53e-24

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 103.34  E-value: 3.53e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796    4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFET--PDNGSI----------------EIDGK 65
Cdd:TIGR03269   1 IEVKNLTKKFDGKEVLKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGMDQyePTSGRIiyhvalcekcgyverpSKVGE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   66 --------------DVVNL-----RPNQRNIGMVFQ-AYALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDH 125
Cdd:TIGR03269  81 pcpvcggtlepeevDFWNLsdklrRRIRKRIAIMLQrTFALYGDDTVLDNVLEALEEIGYEGKEAVGRAVDLIEMVQLSH 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  126 LADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIV 205
Cdd:TIGR03269 161 RITHIARDLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEAVKASGISMVLTSHWPEVIEDLSDKAI 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 559158796  206 VMHEGRADQIGSPFDIynrpASRFVASFVGTLNMLEASVSEPAQNSIDLDGRQITVQ 262
Cdd:TIGR03269 241 WLENGEIKEEGTPDEV----VAVFMEGVSEVEKECEVEVGEPIIKVRNVSKRYISVD 293
PRK13539 PRK13539
cytochrome c biogenesis protein CcmA; Provisional
 4-166 5.92e-24

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 237421 [Multi-domain]  Cd Length: 207  Bit Score: 97.64  E-value: 5.92e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQRnigmvfQA 83
Cdd:PRK13539   3 LEGEDLACVRGGRVLFSGLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLDGGDIDDPDVAEA------CH 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  84 Y-----ALFPNMTVAQNVSFGLRVSGKSRSEIDATvkemLSLIRLDHLADRyPYQM-SGGQQQRVALARALATKPQVLLL 157
Cdd:PRK13539  77 YlghrnAMKPALTVAENLEFWAAFLGGEELDIAAA----LEAVGLAPLAHL-PFGYlSAGQKRRVALARLLVSNRPIWIL 151


                 ....*....
gi 559158796 158 DEPLSALDA 166
Cdd:PRK13539 152 DEPTAALDA 160
znuC PRK09544
high-affinity zinc transporter ATPase; Reviewed
 6-193 7.31e-24

high-affinity zinc transporter ATPase; Reviewed


Pssm-ID: 181939 [Multi-domain]  Cd Length: 251  Bit Score: 98.65  E-value: 7.31e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   6 IKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEidgkdvvnlRPNQRNIGMVFQAYA 85
Cdd:PRK09544   7 LENVSVSFGQRRVLSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGVIK---------RNGKLRIGYVPQKLY 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  86 LFPnmTVAQNVSFGLRVSGKSRSeidATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSALD 165
Cdd:PRK09544  78 LDT--TLPLTVNRFLRLRPGTKK---EDILPALKRVQAGHLIDAPMQKLSGGETQRVLLARALLNRPQLLVLDEPTQGVD 152

                        170       180
                 ....*....|....*....|....*...
gi 559158796 166 AKIRISLREEIRAIQQKLGITTVFVTHD 193
Cdd:PRK09544 153 VNGQVALYDLIDQLRRELDCAVLMVSHD 180
PRK11174 PRK11174
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
 21-217 8.01e-24

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236870 [Multi-domain]  Cd Length: 588  Bit Score: 102.23  E-value: 8.01e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  21 DFNLAvgKGEFVSFLGPSGCGKTTVLRMIAGFeTPDNGSIEIDGKDVVNLRPNQ--RNIGMVFQAYALFPNmTVAQNVSF 98
Cdd:PRK11174 370 NFTLP--AGQRIALVGPSGAGKTSLLNALLGF-LPYQGSLKINGIELRELDPESwrKHLSWVGQNPQLPHG-TLRDNVLL 445

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  99 GlrvsgksrsEIDATVKEMLSLIR-------LDHLADRYPYQ-------MSGGQQQRVALARALATKPQVLLLDEPLSAL 164
Cdd:PRK11174 446 G---------NPDASDEQLQQALEnawvsefLPLLPQGLDTPigdqaagLSVGQAQRLALARALLQPCQLLLLDEPTASL 516

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 559158796 165 DAKiriSLREEIRAIQQ-KLGITTVFVTHdQEEALSISDRIVVMHEGRADQIGS 217
Cdd:PRK11174 517 DAH---SEQLVMQALNAaSRRQTTLMVTH-QLEDLAQWDQIWVMQDGQIVQQGD 566
3a01208 TIGR00958
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
 18-225 8.10e-24

Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273363 [Multi-domain]  Cd Length: 711  Bit Score: 102.49  E-value: 8.10e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   18 VVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVV--NLRPNQRNIGMVFQAYALFpNMTVAQN 95
Cdd:TIGR00958 496 VLKGLTFTLHPGEVVALVGPSGSGKSTVAALLQNLYQPTGGQVLLDGVPLVqyDHHYLHRQVALVGQEPVLF-SGSVREN 574

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   96 VSFGLRVSGKSrsEIDATVKEMLSLIRLDHLADRYPY-------QMSGGQQQRVALARALATKPQVLLLDEPLSALDAKI 168
Cdd:TIGR00958 575 IAYGLTDTPDE--EIMAAAKAANAHDFIMEFPNGYDTevgekgsQLSGGQKQRIAIARALVRKPRVLILDEATSALDAEC 652

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  169 RISLREEiraiQQKLGITTVFVTHDqeeaLSI---SDRIVVMHEGRADQIGSPFDIYNRP 225
Cdd:TIGR00958 653 EQLLQES----RSRASRTVLLIAHR----LSTverADQILVLKKGSVVEMGTHKQLMEDQ 704
ABCC_TAP cd03248
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ...
 18-211 1.92e-23

ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.


Pssm-ID: 213215 [Multi-domain]  Cd Length: 226  Bit Score: 96.77  E-value: 1.92e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  18 VVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVvNLRPNQ---RNIGMVFQAYALFPNmTVAQ 94
Cdd:cd03248   29 VLQDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQVLLDGKPI-SQYEHKylhSKVSLVGQEPVLFAR-SLQD 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  95 NVSFGLR-------VSGKSRSEIDATVKEMLSLIRLDhlADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSALDAK 167
Cdd:cd03248  107 NIAYGLQscsfecvKEAAQKAHAHSFISELASGYDTE--VGEKGSQLSGGQKQRVAIARALIRNPQVLILDEATSALDAE 184

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 559158796 168 IRISLREeirAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGR 211
Cdd:cd03248  185 SEQQVQQ---ALYDWPERRTVLVIAHRLSTVERADQILVLDGGR 225
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
 4-242 2.95e-23

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 100.46  E-value: 2.95e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLkksfgTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQ--RNiGMVF 81
Cdd:PRK10762 258 LKVDNL-----SGPGVNDVSFTLRKGEILGVSGLMGAGRTELMKVLYGALPRTSGYVTLDGHEVVTRSPQDglAN-GIVY 331

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  82 -----QAYALFPNMTVAQNVSF-GLRVSGKSRSEIDATVKEML--SLIRLDHLadRYPYQ------MSGGQQQRVALARA 147
Cdd:PRK10762 332 isedrKRDGLVLGMSVKENMSLtALRYFSRAGGSLKHADEQQAvsDFIRLFNI--KTPSMeqaiglLSGGNQQKVAIARG 409

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 148 LATKPQVLLLDEPLSALDakirISLREEI-RAIQQ--KLGITTVFVTHDQEEALSISDRIVVMHEGRadqIGSPFDIYNR 224
Cdd:PRK10762 410 LMTRPKVLILDEPTRGVD----VGAKKEIyQLINQfkAEGLSIILVSSEMPEVLGMSDRILVMHEGR---ISGEFTREQA 482

                        250
                 ....*....|....*...
gi 559158796 225 PASRFVASFVGTLNMLEA 242
Cdd:PRK10762 483 TQEKLMAAAVGKLNRVNQ 500
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
7-211 5.37e-23

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 100.20  E-value: 5.37e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   7 KNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSI-----EIDGKDvVNLRpnqRNIGMVF 81
Cdd:NF033858 270 RGLTMRFGDFTAVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAwlfgqPVDAGD-IATR---RRVGYMS 345

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  82 QAYALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPL 161
Cdd:NF033858 346 QAFSLYGELTVRQNLELHARLFHLPAAEIAARVAEMLERFDLADVADALPDSLPLGIRQRLSLAVAVIHKPELLILDEPT 425

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 559158796 162 SALDAKIR-------ISL-REEiraiqqklGItTVFV-THDQEEALSiSDRIVVMHEGR 211
Cdd:NF033858 426 SGVDPVARdmfwrllIELsRED--------GV-TIFIsTHFMNEAER-CDRISLMHAGR 474
PRK13538 PRK13538
cytochrome c biogenesis heme-transporting ATPase CcmA;
3-167 7.22e-23

cytochrome c biogenesis heme-transporting ATPase CcmA;


Pssm-ID: 184125 [Multi-domain]  Cd Length: 204  Bit Score: 94.49  E-value: 7.22e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   3 FLNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPN-QRNIGMVF 81
Cdd:PRK13538   1 MLEARNLACERDERILFSGLSFTLNAGELVQIEGPNGAGKTSLLRILAGLARPDAGEVLWQGEPIRRQRDEyHQDLLYLG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  82 QAYALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRypyQMSGGQQQRVALARALATKPQVLLLDEPL 161
Cdd:PRK13538  81 HQPGIKTELTALENLRFYQRLHGPGDDEALWEALAQVGLAGFEDVPVR---QLSAGQQRRVALARLWLTRAPLWILDEPF 157


                 ....*.
gi 559158796 162 SALDAK 167
Cdd:PRK13538 158 TAIDKQ 163
ABC_FeS_Assembly cd03217
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ...
 4-211 1.07e-22

ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.


Pssm-ID: 213184 [Multi-domain]  Cd Length: 200  Bit Score: 94.13  E-value: 1.07e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFE--TPDNGSIEIDGKDVVNLRPNQR---NIG 78
Cdd:cd03217    1 LEIKDLHVSVGGKEILKGVNLTIKKGEVHALMGPNGSGKSTLAKTIMGHPkyEVTEGEILFKGEDITDLPPEERarlGIF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  79 MVFQAYALFPNMTVAQ-----NVSFglrvsgksrseidatvkemlslirldhladrypyqmSGGQQQRVALARALATKPQ 153
Cdd:cd03217   81 LAFQYPPEIPGVKNADflryvNEGF------------------------------------SGGEKKRNEILQLLLLEPD 124

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 559158796 154 VLLLDEPLSALDAKiriSLREEIRAIQQ--KLGITTVFVTHDQEEALSI-SDRIVVMHEGR 211
Cdd:cd03217  125 LAILDEPDSGLDID---ALRLVAEVINKlrEEGKSVLIITHYQRLLDYIkPDRVHVLYDGR 182
ABCG_White cd03234
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ...
 18-211 2.16e-22

White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.


Pssm-ID: 213201 [Multi-domain]  Cd Length: 226  Bit Score: 93.87  E-value: 2.16e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  18 VVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFEtpDNGSIeIDGKDVVNLRPN-----QRNIGMVFQAYALFPNMTV 92
Cdd:cd03234   22 ILNDVSLHVESGQVMAILGSSGSGKTTLLDAISGRV--EGGGT-TSGQILFNGQPRkpdqfQKCVAYVRQDDILLPGLTV 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  93 AQNVSFGLRV------SGKSRSEIDATVkeMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSALDA 166
Cdd:cd03234   99 RETLTYTAILrlprksSDAIRKKRVEDV--LLRDLALTRIGGNLVKGISGGERRRVSIAVQLLWDPKVLILDEPTSGLDS 176

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 559158796 167 KIRISLREEIR--AIQQKLGITTVfvtHD-QEEALSISDRIVVMHEGR 211
Cdd:cd03234  177 FTALNLVSTLSqlARRNRIVILTI---HQpRSDLFRLFDRILLLSSGE 221
ABC_CcmA_heme_exporter cd03231
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ...
 4-192 2.64e-22

Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.


Pssm-ID: 213198 [Multi-domain]  Cd Length: 201  Bit Score: 92.94  E-value: 2.64e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPN-QRNIGMVFQ 82
Cdd:cd03231    1 LEADELTCERDGRALFSGLSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVLLNGGPLDFQRDSiARGLLYLGH 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  83 AYALFPNMTVAQNVSFGLRVSGksrseiDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLS 162
Cdd:cd03231   81 APGIKTTLSVLENLRFWHADHS------DEQVEEALARVGLNGFEDRPVAQLSAGQQRRVALARLLLSGRPLWILDEPTT 154

                        170       180       190
                 ....*....|....*....|....*....|
gi 559158796 163 ALDAKIRISLREEIRAIQQKLGItTVFVTH 192
Cdd:cd03231  155 ALDKAGVARFAEAMAGHCARGGM-VVLTTH 183
BtuD COG4138
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ...
 22-211 1.42e-21

ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];


Pssm-ID: 443313 [Multi-domain]  Cd Length: 248  Bit Score: 92.21  E-value: 1.42e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  22 FNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFeTPDNGSIEIDGKDVVNLRPNQ--RNIGMVFQAYALFPNMTVAQNVSFG 99
Cdd:COG4138   15 ISAQVNAGELIHLIGPNGAGKSTLLARMAGL-LPGQGEILLNGRPLSDWSAAElaRHRAYLSQQQSPPFAMPVFQYLALH 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 100 LRVSGkSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARAL-----ATKP--QVLLLDEPLSALDAKIRISL 172
Cdd:COG4138   94 QPAGA-SSEAVEQLLAQLAEALGLEDKLSRPLTQLSGGEWQRVRLAAVLlqvwpTINPegQLLLLDEPMNSLDVAQQAAL 172

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 559158796 173 REEIRAIQQkLGITTVFVTHDQEEALSISDRIVVMHEGR 211
Cdd:COG4138  173 DRLLRELCQ-QGITVVMSSHDLNHTLRHADRVWLLKQGK 210
PRK13540 PRK13540
cytochrome c biogenesis protein CcmA; Provisional
 4-202 1.58e-21

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 184127 [Multi-domain]  Cd Length: 200  Bit Score: 90.78  E-value: 1.58e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDV-VNLRPNQRNIGMVFQ 82
Cdd:PRK13540   2 LDVIELDFDYHDQPLLQQISFHLPAGGLLHLKGSNGAGKTTLLKLIAGLLNPEKGEILFERQSIkKDLCTYQKQLCFVGH 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  83 AYALFPNMTVAQNVSFGLRVSGKSRsEIDatvkEMLSLIRLDHLADrYPYQM-SGGQQQRVALARALATKPQVLLLDEPL 161
Cdd:PRK13540  82 RSGINPYLTLRENCLYDIHFSPGAV-GIT----ELCRLFSLEHLID-YPCGLlSSGQKRQVALLRLWMSKAKLWLLDEPL 155

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 559158796 162 SALDAKIRISLREEIRAIQQKLGitTVFVTHDQEEALSISD 202
Cdd:PRK13540 156 VALDELSLLTIITKIQEHRAKGG--AVLLTSHQDLPLNKAD 194
bacteriocin_ABC TIGR01193
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The ...
 4-224 4.47e-21

ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The amino terminal domain (pfam03412) processes the N-terminal leader peptide from the bacteriocin while C-terminal domains resemble ABC transporter membrane protein and ATP-binding cassette domain. In general, bacteriocins are agents which are responsible for killing or inhibiting the closely related species or even different strains of the same species. Bacteriocins are usually encoded by bacterial plasmids. Bacteriocins are named after the species and hence in literature one encounters various names e.g., leucocin from Leuconostic geldium; pedicocin from Pedicoccus acidilactici; sakacin from Lactobacillus sake etc. [Protein fate, Protein and peptide secretion and trafficking, Protein fate, Protein modification and repair, Transport and binding proteins, Other]


Pssm-ID: 130261 [Multi-domain]  Cd Length: 708  Bit Score: 94.42  E-value: 4.47e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796    4 LNIKNLKKSFGTNT-VVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQ--RNIGMV 80
Cdd:TIGR01193 474 IVINDVSYSYGYGSnILSDISLTIKMNSKTTIVGMSGSGKSTLAKLLVGFFQARSGEILLNGFSLKDIDRHTlrQFINYL 553

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   81 FQAYALFPNmTVAQNVSFGLRvSGKSRSEIDATVKemLSLIRLDHLADRYPYQ---------MSGGQQQRVALARALATK 151
Cdd:TIGR01193 554 PQEPYIFSG-SILENLLLGAK-ENVSQDEIWAACE--IAEIKDDIENMPLGYQtelseegssISGGQKQRIALARALLTD 629

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 559158796  152 PQVLLLDEPLSALDAKIRISLREEIRAIQQKlgiTTVFVTHDQEEAlSISDRIVVMHEGRADQIGSPFDIYNR 224
Cdd:TIGR01193 630 SKVLILDESTSNLDTITEKKIVNNLLNLQDK---TIIFVAHRLSVA-KQSDKIIVLDHGKIIEQGSHDELLDR 698
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
1-235 5.53e-21

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 93.82  E-value: 5.53e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   1 MAFLNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVnlRPNQRN---- 76
Cdd:PRK11288   2 SPYLSFDGIGKTFPGVKALDDISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGSILIDGQEMR--FASTTAalaa 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  77 -IGMVFQAYALFPNMTVAQNVSFGlRVSGKS----RSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATK 151
Cdd:PRK11288  80 gVAIIYQELHLVPEMTVAENLYLG-QLPHKGgivnRRLLNYEAREQLEHLGVDIDPDTPLKYLSIGQRQMVEIAKALARN 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 152 PQVLLLDEPLSALDAK--------IRiSLREEIRAIqqklgittVFVTHDQEEALSISDRIVVMHEGRadQIGSPFDIYN 223
Cdd:PRK11288 159 ARVIAFDEPTSSLSAReieqlfrvIR-ELRAEGRVI--------LYVSHRMEEIFALCDAITVFKDGR--YVATFDDMAQ 227

                        250
                 ....*....|..
gi 559158796 224 RPASRFVASFVG 235
Cdd:PRK11288 228 VDRDQLVQAMVG 239
ABCC_NFT1 cd03369
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ...
 4-218 8.50e-21

ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213269 [Multi-domain]  Cd Length: 207  Bit Score: 89.01  E-value: 8.50e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTN--TVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDV--VNLRPNQRNIGM 79
Cdd:cd03369    7 IEVENLSVRYAPDlpPVLKNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAEEGKIEIDGIDIstIPLEDLRSSLTI 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  80 VFQAYALFpnmtvaqnvsfglrvSGKSRSEIDatvkemlsliRLDHLADRYPYQ----------MSGGQQQRVALARALA 149
Cdd:cd03369   87 IPQDPTLF---------------SGTIRSNLD----------PFDEYSDEEIYGalrvsegglnLSQGQRQLLCLARALL 141

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 559158796 150 TKPQVLLLDEPLSAL----DAKIRISLREEIRaiqqklGITTVFVTHdQEEALSISDRIVVMHEGRADQIGSP 218
Cdd:cd03369  142 KRPRVLVLDEATASIdyatDALIQKTIREEFT------NSTILTIAH-RLRTIIDYDKILVMDAGEVKEYDHP 207
ABCG_PDR_domain1 cd03233
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ...
 1-211 1.06e-20

First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213200 [Multi-domain]  Cd Length: 202  Bit Score: 88.47  E-value: 1.06e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   1 MAFLNI-KNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGfETPDNGSIE-------IDGKDvvNLRP 72
Cdd:cd03233    4 LSWRNIsFTTGKGRSKIPILKDFSGVVKPGEMVLVLGRPGSGCSTLLKALAN-RTEGNVSVEgdihyngIPYKE--FAEK 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  73 NQRNIGMVFQAYALFPNMTVAQNVSFGLRVSGksrseidatvkemlslirldhlaDRYPYQMSGGQQQRVALARALATKP 152
Cdd:cd03233   81 YPGEIIYVSEEDVHFPTLTVRETLDFALRCKG-----------------------NEFVRGISGGERKRVSIAEALVSRA 137

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 559158796 153 QVLLLDEPLSALDAKIRISLREEIRAIQQKLGiTTVFVTHDQ--EEALSISDRIVVMHEGR 211
Cdd:cd03233  138 SVLCWDNSTRGLDSSTALEILKCIRTMADVLK-TTTFVSLYQasDEIYDLFDKVLVLYEGR 197
SapD COG4170
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];
1-225 1.10e-20

ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];


Pssm-ID: 443330 [Multi-domain]  Cd Length: 331  Bit Score: 91.12  E-value: 1.10e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   1 MAFLNIKNLKKSFGTNT----VVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFeTPDNGSIEID-----GKDVVNLR 71
Cdd:COG4170    1 MPLLDIRNLTIEIDTPQgrvkAVDRVSLTLNEGEIRGLVGESGSGKSLIAKAICGI-TKDNWHVTADrfrwnGIDLLKLS 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  72 PNQR------NIGMVFQ---AYaLFPNMTVAQNVSFGL---RVSGK------SRSEIdatVKEMLSL--IRlDHLA--DR 129
Cdd:COG4170   80 PRERrkiigrEIAMIFQepsSC-LDPSAKIGDQLIEAIpswTFKGKwwqrfkWRKKR---AIELLHRvgIK-DHKDimNS 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 130 YPYQMSGGQQQRVALARALATKPQVLLLDEPLSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHE 209
Cdd:COG4170  155 YPHELTEGECQKVMIAMAIANQPRLLIADEPTNAMESTTQAQIFRLLARLNQLQGTSILLISHDLESISQWADTITVLYC 234

                        250
                 ....*....|....*.
gi 559158796 210 GRADQIGSPFDIYNRP 225
Cdd:COG4170  235 GQTVESGPTEQILKSP 250
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
 19-211 1.66e-20

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 92.20  E-value: 1.66e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   19 VHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAG-FETPDNGSIEIDGKDVVNLRPNQ---RNIGMV---FQAYALFPNMT 91
Cdd:TIGR02633 276 VDDVSFSLRRGEILGVAGLVGAGRTELVQALFGaYPGKFEGNVFINGKPVDIRNPAQairAGIAMVpedRKRHGIVPILG 355

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   92 VAQNVSFGL--RVSGKSRSEIDATVKEMLSLIRLDHLADRYPY----QMSGGQQQRVALARALATKPQVLLLDEPLSALD 165
Cdd:TIGR02633 356 VGKNITLSVlkSFCFKMRIDAAAELQIIGSAIQRLKVKTASPFlpigRLSGGNQQKAVLAKMLLTNPRVLILDEPTRGVD 435

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 559158796  166 AKIRISLREEIRAIQQKlGITTVFVTHDQEEALSISDRIVVMHEGR 211
Cdd:TIGR02633 436 VGAKYEIYKLINQLAQE-GVAIIVVSSELAEVLGLSDRVLVIGEGK 480
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
 4-193 2.21e-20

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 92.31  E-value: 2.21e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796    4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIdGKDVVnlrpnqrnIGMVFQA 83
Cdd:TIGR03719 323 IEAENLTKAFGDKLLIDDLSFKLPPGGIVGVIGPNGAGKSTLFRMITGQEQPDSGTIEI-GETVK--------LAYVDQS 393

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   84 Y-ALFPNMTVAQNVSFGLrvsgksrSEIDATVKEMLSLIRLDHL----ADRYPY--QMSGGQQQRVALARALATKPQVLL 156
Cdd:TIGR03719 394 RdALDPNKTVWEEISGGL-------DIIKLGKREIPSRAYVGRFnfkgSDQQKKvgQLSGGERNRVHLAKTLKSGGNVLL 466

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 559158796  157 LDEPLSALDAkirislrEEIRAIQQKL---GITTVFVTHD 193
Cdd:TIGR03719 467 LDEPTNDLDV-------ETLRALEEALlnfAGCAVVISHD 499
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
 18-211 2.37e-20

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 91.91  E-value: 2.37e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  18 VVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAG-FETPDNGSIEIDGKDVVNLRPNQ---RNIGMVFQ---AYALFPNM 90
Cdd:PRK13549 277 RVDDVSFSLRRGEILGIAGLVGAGRTELVQCLFGaYPGRWEGEIFIDGKPVKIRNPQQaiaQGIAMVPEdrkRDGIVPVM 356

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  91 TVAQNVSFGL--RVSGKSR----SEIDATVKEMLSL-IRLDHLADRYPyQMSGGQQQRVALARALATKPQVLLLDEPLSA 163
Cdd:PRK13549 357 GVGKNITLAAldRFTGGSRiddaAELKTILESIQRLkVKTASPELAIA-RLSGGNQQKAVLAKCLLLNPKILILDEPTRG 435

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 559158796 164 LDakirISLREEI-RAIQQ--KLGITTVFVTHDQEEALSISDRIVVMHEGR 211
Cdd:PRK13549 436 ID----VGAKYEIyKLINQlvQQGVAIIVISSELPEVLGLSDRVLVMHEGK 482
ABCD_peroxisomal_ALDP cd03223
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ...
 16-192 3.66e-20

ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).


Pssm-ID: 213190 [Multi-domain]  Cd Length: 166  Bit Score: 86.05  E-value: 3.66e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  16 NTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEidgkdvvnlRPNQRNIGMVFQAyalfPNMTvaqn 95
Cdd:cd03223   14 RVLLKDLSFEIKPGDRLLITGPSGTGKSSLFRALAGLWPWGSGRIG---------MPEGEDLLFLPQR----PYLP---- 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  96 vsfglrvsgksrseiDATVKEMLSlirldhladrYPYQM--SGGQQQRVALARALATKPQVLLLDEPLSALDAKIRISLR 173
Cdd:cd03223   77 ---------------LGTLREQLI----------YPWDDvlSGGEQQRLAFARLLLHKPKFVFLDEATSALDEESEDRLY 131

                        170
                 ....*....|....*....
gi 559158796 174 EEIRaiqqKLGITTVFVTH 192
Cdd:cd03223  132 QLLK----ELGITVISVGH 146
cbiO PRK13638
energy-coupling factor ABC transporter ATP-binding protein;
18-224 3.82e-20

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184198 [Multi-domain]  Cd Length: 271  Bit Score: 88.91  E-value: 3.82e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  18 VVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDV----VNLRPNQRNIGMVFQAyalfPNMTV- 92
Cdd:PRK13638  16 VLKGLNLDFSLSPVTGLVGANGCGKSTLFMNLSGLLRPQKGAVLWQGKPLdyskRGLLALRQQVATVFQD----PEQQIf 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  93 ----AQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRyPYQ-MSGGQQQRVALARALATKPQVLLLDEPLSALDAK 167
Cdd:PRK13638  92 ytdiDSDIAFSLRNLGVPEAEITRRVDEALTLVDAQHFRHQ-PIQcLSHGQKKRVAIAGALVLQARYLLLDEPTAGLDPA 170

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 559158796 168 IRISLREEIRAIQQKlGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNR 224
Cdd:PRK13638 171 GRTQMIAIIRRIVAQ-GNHVIISSHDIDLIYEISDAVYVLRQGQILTHGAPGEVFAC 226
PRK10575 PRK10575
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
17-221 4.58e-20

Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;


Pssm-ID: 182561 [Multi-domain]  Cd Length: 265  Bit Score: 88.31  E-value: 4.58e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  17 TVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVV--NLRPNQRNIGMVFQAYALFPNMTVAQ 94
Cdd:PRK10575  25 TLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLEswSSKAFARKVAYLPQQLPAAEGMTVRE 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  95 NVSFGLR----VSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSALDAKIRI 170
Cdd:PRK10575 105 LVAIGRYpwhgALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQV 184

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 559158796 171 SLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDI 221
Cdd:PRK10575 185 DVLALVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEL 235
ABC_RNaseL_inhibitor_domain2 cd03237
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
 21-206 4.64e-20

The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213204 [Multi-domain]  Cd Length: 246  Bit Score: 87.85  E-value: 4.64e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  21 DFNLAVGKGEF-----VSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVvNLRPNQrnIGMVFQayalfpnMTVAQN 95
Cdd:cd03237   12 EFTLEVEGGSIsesevIGILGPNGIGKTTFIKMLAGVLKPDEGDIEIELDTV-SYKPQY--IKADYE-------GTVRDL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  96 VSFGLRVSGKS---RSEIdatvkemLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSALDAKIRISL 172
Cdd:cd03237   82 LSSITKDFYTHpyfKTEI-------AKPLQIEQILDREVPELSGGELQRVAIAACLSKDADIYLLDEPSAYLDVEQRLMA 154

                        170       180       190
                 ....*....|....*....|....*....|....
gi 559158796 173 REEIRAIQQKLGITTVFVTHDQEEALSISDRIVV 206
Cdd:cd03237  155 SKVIRRFAENNEKTAFVVEHDIIMIDYLADRLIV 188
nikD PRK10418
nickel transporter ATP-binding protein NikD; Provisional
 19-228 9.19e-20

nickel transporter ATP-binding protein NikD; Provisional


Pssm-ID: 236688 [Multi-domain]  Cd Length: 254  Bit Score: 87.45  E-value: 9.19e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  19 VHDFNLAVGKGEFVSFLGPSGCGKT----TVLRMIAGFETPDNGSIEIDGKDVVNLRPNQRNIGMVFQA--YALFPNMTV 92
Cdd:PRK10418  19 VHGVSLTLQRGRVLALVGGSGSGKSltcaAALGILPAGVRQTAGRVLLDGKPVAPCALRGRKIATIMQNprSAFNPLHTM 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  93 AQNVSFGLRVSGKSRSeiDATVKEMLSLIRLDH---LADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSALD--AK 167
Cdd:PRK10418  99 HTHARETCLALGKPAD--DATLTAALEAVGLENaarVLKLYPFEMSGGMLQRMMIALALLCEAPFIIADEPTTDLDvvAQ 176

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 559158796 168 IRI-SLREEIRAiQQKLGIttVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNRPASR 228
Cdd:PRK10418 177 ARIlDLLESIVQ-KRALGM--LLVTHDMGVVARLADDVAVMSHGRIVEQGDVETLFNAPKHA 235
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
 8-221 9.66e-20

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 90.23  E-value: 9.66e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   8 NLKKSFGtntvvhDFNLAVG-----KGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDgkdvvnlrpnqrnigmvfq 82
Cdd:COG1245  346 DLTKSYG------GFSLEVEggeirEGEVLGIVGPNGIGKTTFAKILAGVLKPDEGEVDED------------------- 400

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  83 ayalfpnmtvaqnvsfgLRVSGKS---RSEIDATVKEMLS---------------LIR---LDHLADRYPYQMSGGQQQR 141
Cdd:COG1245  401 -----------------LKISYKPqyiSPDYDGTVEEFLRsantddfgssyykteIIKplgLEKLLDKNVKDLSGGELQR 463

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 142 VALARALATKPQVLLLDEPLSALDAKIRISLREEIRAIQQKLGITTVFVTHDqeeaLS----ISDRIVVM-----HEGRA 212
Cdd:COG1245  464 VAIAACLSRDADLYLLDEPSAHLDVEQRLAVAKAIRRFAENRGKTAMVVDHD----IYlidyISDRLMVFegepgVHGHA 539


                 ....*....
gi 559158796 213 DqigSPFDI 221
Cdd:COG1245  540 S---GPMDM 545
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
3-210 1.39e-19

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 89.46  E-value: 1.39e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   3 FLNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPN---QRNIGM 79
Cdd:PRK09700   5 YISMAGIGKSFGPVHALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNINYNKLDHKlaaQLGIGI 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  80 VFQAYALFPNMTVAQNVSFGLRVSGK-------SRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKP 152
Cdd:PRK09700  85 IYQELSVIDELTVLENLYIGRHLTKKvcgvniiDWREMRVRAAMMLLRVGLKVDLDEKVANLSISHKQMLEIAKTLMLDA 164

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 559158796 153 QVLLLDEPLSALDAK-------IRISLREEIRAIqqklgittVFVTHDQEEALSISDRIVVMHEG 210
Cdd:PRK09700 165 KVIIMDEPTSSLTNKevdylflIMNQLRKEGTAI--------VYISHKLAEIRRICDRYTVMKDG 221
PRK11176 PRK11176
lipid A ABC transporter ATP-binding protein/permease MsbA;
20-211 1.46e-19

lipid A ABC transporter ATP-binding protein/permease MsbA;


Pssm-ID: 183016 [Multi-domain]  Cd Length: 582  Bit Score: 89.69  E-value: 1.46e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  20 HDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDV-----VNLRpnqRNIGMVFQAYALFpNMTVAQ 94
Cdd:PRK11176 360 RNINFKIPAGKTVALVGRSGSGKSTIANLLTRFYDIDEGEILLDGHDLrdytlASLR---NQVALVSQNVHLF-NDTIAN 435

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  95 NVSFGlRVSGKSRSEIDATVK---EMLSLIRLDHLADRYPYQ----MSGGQQQRVALARALATKPQVLLLDEPLSALDAk 167
Cdd:PRK11176 436 NIAYA-RTEQYSREQIEEAARmayAMDFINKMDNGLDTVIGEngvlLSGGQRQRIAIARALLRDSPILILDEATSALDT- 513

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 559158796 168 irislrEEIRAIQQKLGI----TTVFVTHDQEEALSISDRIVVMHEGR 211
Cdd:PRK11176 514 ------ESERAIQAALDElqknRTSLVIAHRLSTIEKADEILVVEDGE 555
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
8-221 1.83e-19

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 89.48  E-value: 1.83e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   8 NLKKSFGtntvvhDFNLAVG-----KGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDgkdvvnlrpnqrnigmvfq 82
Cdd:PRK13409 345 DLTKKLG------DFSLEVEggeiyEGEVIGIVGPNGIGKTTFAKLLAGVLKPDEGEVDPE------------------- 399

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  83 ayalfpnmtvaqnvsfgLRVSGKS---RSEIDATVKEMLSLI-----------------RLDHLADRYPYQMSGGQQQRV 142
Cdd:PRK13409 400 -----------------LKISYKPqyiKPDYDGTVEDLLRSItddlgssyykseiikplQLERLLDKNVKDLSGGELQRV 462

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 143 ALARALATKPQVLLLDEPLSALDAKIRISLREEIRAIQQKLGITTVFVTHD---QEealSISDRIVVM-----HEGRADq 214
Cdd:PRK13409 463 AIAACLSRDADLYLLDEPSAHLDVEQRLAVAKAIRRIAEEREATALVVDHDiymID---YISDRLMVFegepgKHGHAS- 538


                 ....*..
gi 559158796 215 igSPFDI 221
Cdd:PRK13409 539 --GPMDM 543
PRK10790 PRK10790
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
4-217 3.76e-19

SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;


Pssm-ID: 182733 [Multi-domain]  Cd Length: 592  Bit Score: 88.62  E-value: 3.76e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGT-NTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNL--RPNQRNIGMV 80
Cdd:PRK10790 341 IDIDNVSFAYRDdNLVLQNINLSVPSRGFVALVGHTGSGKSTLASLLMGYYPLTEGEIRLDGRPLSSLshSVLRQGVAMV 420

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  81 FQ-----AYALFPNMTVAQNVSfglrvsgksrseiDATVKEMLSLIRLDHLADRYP-----------YQMSGGQQQRVAL 144
Cdd:PRK10790 421 QQdpvvlADTFLANVTLGRDIS-------------EEQVWQALETVQLAELARSLPdglytplgeqgNNLSVGQKQLLAL 487

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 559158796 145 ARALATKPQVLLLDEPLSALDAKIRISLREEIRAIQQKlgiTTVFVTHDQEEALSISDRIVVMHEGRADQIGS 217
Cdd:PRK10790 488 ARVLVQTPQILILDEATANIDSGTEQAIQQALAAVREH---TTLVVIAHRLSTIVEADTILVLHRGQAVEQGT 557
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
20-211 3.85e-19

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 88.43  E-value: 3.85e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  20 HDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKdVVNLRPNQRNI--GMVF-----QAYALFPNMTV 92
Cdd:PRK11288 270 EPISFSVRAGEIVGLFGLVGAGRSELMKLLYGATRRTAGQVYLDGK-PIDIRSPRDAIraGIMLcpedrKAEGIIPVHSV 348

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  93 AQNVS---------FGLRVSGKSRSEidatvkemlslirldhLADRYPYQM--------------SGGQQQRVALARALA 149
Cdd:PRK11288 349 ADNINisarrhhlrAGCLINNRWEAE----------------NADRFIRSLniktpsreqlimnlSGGNQQKAILGRWLS 412

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 559158796 150 TKPQVLLLDEPLSALDakirISLREEIRAIQQKL---GITTVFVTHDQEEALSISDRIVVMHEGR 211
Cdd:PRK11288 413 EDMKVILLDEPTRGID----VGAKHEIYNVIYELaaqGVAVLFVSSDLPEVLGVADRIVVMREGR 473
ABCC_MRP_domain2 cd03244
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ...
 6-218 5.98e-19

ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213211 [Multi-domain]  Cd Length: 221  Bit Score: 84.08  E-value: 5.98e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   6 IKNLKKSF--GTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTV----LRMIagfeTPDNGSIEIDGKDVVNLRPNQ--RNI 77
Cdd:cd03244    5 FKNVSLRYrpNLPPVLKNISFSIKPGEKVGIVGRTGSGKSSLllalFRLV----ELSSGSILIDGVDISKIGLHDlrSRI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  78 GMVFQAYALFPNmTVAQNV-SFGLrvsgKSRSEI-----DATVKEMLS--LIRLDHLADRYPYQMSGGQQQRVALARALA 149
Cdd:cd03244   81 SIIPQDPVLFSG-TIRSNLdPFGE----YSDEELwqaleRVGLKEFVEslPGGLDTVVEEGGENLSVGQRQLLCLARALL 155

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 559158796 150 TKPQVLLLDEPLSALD----AKIRISLREEIRaiqqklGITTVFVTHDQEEALSiSDRIVVMHEGRADQIGSP 218
Cdd:cd03244  156 RKSKILVLDEATASVDpetdALIQKTIREAFK------DCTVLTIAHRLDTIID-SDRILVLDKGRVVEFDSP 221
PRK11160 PRK11160
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
 4-211 6.14e-19

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236865 [Multi-domain]  Cd Length: 574  Bit Score: 87.96  E-value: 6.14e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLkkSFG----TNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVV-----NLRpnq 74
Cdd:PRK11160 339 LTLNNV--SFTypdqPQPVLKGLSLQIKAGEKVALLGRTGCGKSTLLQLLTRAWDPQQGEILLNGQPIAdyseaALR--- 413

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  75 RNIGMVFQAYALFpNMTVAQNVSFGlrvsgkSRSEIDATVKEMLSLIRLDHLAD-------------RypyQMSGGQQQR 141
Cdd:PRK11160 414 QAISVVSQRVHLF-SATLRDNLLLA------APNASDEALIEVLQQVGLEKLLEddkglnawlgeggR---QLSGGEQRR 483

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 559158796 142 VALARALATKPQVLLLDEPLSALDAK----IRISLREEiraIQQKlgiTTVFVTHdQEEALSISDRIVVMHEGR 211
Cdd:PRK11160 484 LGIARALLHDAPLLLLDEPTEGLDAEterqILELLAEH---AQNK---TVLMITH-RLTGLEQFDRICVMDNGQ 550
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
 21-211 1.79e-18

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 86.26  E-value: 1.79e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  21 DFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQR-NIGMVF-----QAYALFPNMTVAQ 94
Cdd:PRK15439 281 NISLEVRAGEILGLAGVVGAGRTELAETLYGLRPARGGRIMLNGKEINALSTAQRlARGLVYlpedrQSSGLYLDAPLAW 360

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  95 NVSfGLRVSGKS---RSEIDATVKEML--SL-IRLDHlADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSALDAKI 168
Cdd:PRK15439 361 NVC-ALTHNRRGfwiKPARENAVLERYrrALnIKFNH-AEQAARTLSGGNQQKVLIAKCLEASPQLLIVDEPTRGVDVSA 438

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 559158796 169 RISLREEIRAIQQKlGITTVFVTHDQEEALSISDRIVVMHEGR 211
Cdd:PRK15439 439 RNDIYQLIRSIAAQ-NVAVLFISSDLEEIEQMADRVLVMHQGE 480
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
 2-210 2.05e-18

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 86.21  E-value: 2.05e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   2 AFLNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRP---NQRNIG 78
Cdd:PRK10762   3 ALLQLKGIDKAFPGVKALSGAALNVYPGRVMALVGENGAGKSTMMKVLTGIYTRDAGSILYLGKEVTFNGPkssQEAGIG 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  79 MVFQAYALFPNMTVAQNV--------SFGLRVSGKSRSEIDAtvkeMLSLIRLDHLADRYPYQMSGGQQQRVALARALAT 150
Cdd:PRK10762  83 IIHQELNLIPQLTIAENIflgrefvnRFGRIDWKKMYAEADK----LLARLNLRFSSDKLVGELSIGEQQMVEIAKVLSF 158

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 559158796 151 KPQVLLLDEPLSALDAKIRISLREEIRAIQ-QKLGIttVFVTHDQEEALSISDRIVVMHEG 210
Cdd:PRK10762 159 ESKVIIMDEPTDALTDTETESLFRVIRELKsQGRGI--VYISHRLKEIFEICDDVTVFRDG 217
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
19-215 4.47e-18

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 85.22  E-value: 4.47e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  19 VHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPN---QRNIGMVFQAY---ALFPNMTV 92
Cdd:PRK09700 279 VRDISFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRAGGEIRLNGKDISPRSPLdavKKGMAYITESRrdnGFFPNFSI 358

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  93 AQNVS-------------FGLrVSGKSRSEIDATVKEMLSLirLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDE 159
Cdd:PRK09700 359 AQNMAisrslkdggykgaMGL-FHEVDEQRTAENQRELLAL--KCHSVNQNITELSGGNQQKVLISKWLCCCPEVIIFDE 435

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 559158796 160 PLSALDakirISLREEIRAIQQKL---GITTVFVTHDQEEALSISDRIVVMHEGRADQI 215
Cdd:PRK09700 436 PTRGID----VGAKAEIYKVMRQLaddGKVILMVSSELPEIITVCDRIAVFCEGRLTQI 490
3a01204 TIGR00955
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ...
 29-218 2.42e-17

The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273361 [Multi-domain]  Cd Length: 617  Bit Score: 83.17  E-value: 2.42e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   29 GEFVSFLGPSGCGKTTVLRMIAGFETPD---NGSIEIDGKdVVNLRPNQRNIGMVFQAYALFPNMTVAQNVSF------G 99
Cdd:TIGR00955  51 GELLAVMGSSGAGKTTLMNALAFRSPKGvkgSGSVLLNGM-PIDAKEMRAISAYVQQDDLFIPTLTVREHLMFqahlrmP 129

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  100 LRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQM---SGGQQQRVALARALATKPQVLLLDEPLSALDAKIRISLREEI 176
Cdd:TIGR00955 130 RRVTKKEKRERVDEVLQALGLRKCANTRIGVPGRVkglSGGERKRLAFASELLTDPPLLFCDEPTSGLDSFMAYSVVQVL 209

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 559158796  177 RAIQQKlGITTVFVTHD-QEEALSISDRIVVMHEGRADQIGSP 218
Cdd:TIGR00955 210 KGLAQK-GKTIICTIHQpSSELFELFDKIILMAEGRVAYLGSP 251
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
 7-165 2.56e-17

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 82.86  E-value: 2.56e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   7 KNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIdGKDVvnlrpnqrNIGMVFQAY-A 85
Cdd:PRK11819 328 ENLSKSFGDRLLIDDLSFSLPPGGIVGIIGPNGAGKSTLFKMITGQEQPDSGTIKI-GETV--------KLAYVDQSRdA 398

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  86 LFPNMTVAQNVSFGL---RVSGK---SRSEIDA----------TVKemlslirldhladrypyQMSGGQQQRVALARALA 149
Cdd:PRK11819 399 LDPNKTVWEEISGGLdiiKVGNReipSRAYVGRfnfkggdqqkKVG-----------------VLSGGERNRLHLAKTLK 461

                        170
                 ....*....|....*.
gi 559158796 150 TKPQVLLLDEPLSALD 165
Cdd:PRK11819 462 QGGNVLLLDEPTNDLD 477
hmuV PRK13547
heme ABC transporter ATP-binding protein;
4-226 1.01e-16

heme ABC transporter ATP-binding protein;


Pssm-ID: 184132 [Multi-domain]  Cd Length: 272  Bit Score: 79.10  E-value: 1.01e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGfETPD---------NGSIEIDGKDVVNLRPNQ 74
Cdd:PRK13547   2 LTADHLHVARRHRAILRDLSLRIEPGRVTALLGRNGAGKSTLLKALAG-DLTGggaprgarvTGDVTLNGEPLAAIDAPR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  75 ---RNIGMVFQAYALFPnMTVAQNVSFG----LRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARA 147
Cdd:PRK13547  81 larLRAVLPQAAQPAFA-FSAREIVLLGryphARRAGALTHRDGEIAWQALALAGATALVGRDVTTLSGGELARVQFARV 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 148 LA---------TKPQVLLLDEPLSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSP 218
Cdd:PRK13547 160 LAqlwpphdaaQPPRYLLLDEPTAALDLAHQHRLLDTVRRLARDWNLGVLAIVHDPNLAARHADRIAMLADGAIVAHGAP 239


                 ....*...
gi 559158796 219 FDIYnRPA 226
Cdd:PRK13547 240 ADVL-TPA 246
PRK15093 PRK15093
peptide ABC transporter ATP-binding protein SapD;
1-225 1.31e-16

peptide ABC transporter ATP-binding protein SapD;


Pssm-ID: 185049 [Multi-domain]  Cd Length: 330  Bit Score: 79.46  E-value: 1.31e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   1 MAFLNIKNLKKSFGTN----TVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFeTPDNGSI-----EIDGKDVVNLR 71
Cdd:PRK15093   1 MPLLDIRNLTIEFKTSdgwvKAVDRVSMTLTEGEIRGLVGESGSGKSLIAKAICGV-TKDNWRVtadrmRFDDIDLLRLS 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  72 PNQR------NIGMVFQ--AYALFPNMTVAQNVSFGL-----------RVSGKSRSEIdatvkEMLSLIRL-DH--LADR 129
Cdd:PRK15093  80 PRERrklvghNVSMIFQepQSCLDPSERVGRQLMQNIpgwtykgrwwqRFGWRKRRAI-----ELLHRVGIkDHkdAMRS 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 130 YPYQMSGGQQQRVALARALATKPQVLLLDEPLSALDAKIRISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHE 209
Cdd:PRK15093 155 FPYELTEGECQKVMIAIALANQPRLLIADEPTNAMEPTTQAQIFRLLTRLNQNNNTTILLISHDLQMLSQWADKINVLYC 234

                        250
                 ....*....|....*.
gi 559158796 210 GRADQIGSPFDIYNRP 225
Cdd:PRK15093 235 GQTVETAPSKELVTTP 250
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
 4-217 1.67e-16

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 81.21  E-value: 1.67e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796     4 LNIKNLKKSF-GTNTVVHDfNLAVG--KGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVV-NLRPNQRNIGM 79
Cdd:TIGR01257 1938 LRLNELTKVYsGTSSPAVD-RLCVGvrPGECFGLLGVNGAGKTTTFKMLTGDTTVTSGDATVAGKSILtNISDVHQNMGY 2016

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796    80 VFQAYALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDE 159
Cdd:TIGR01257 2017 CPQFDAIDDLLTGREHLYLYARLRGVPAEEIEKVANWSIQSLGLSLYADRLAGTYSGGNKRKLSTAIALIGCPPLVLLDE 2096

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 559158796   160 PLSALDAKIRISLREEIRAIQQKlGITTVFVTHDQEEALSISDRIVVMHEGRADQIGS 217
Cdd:TIGR01257 2097 PTTGMDPQARRMLWNTIVSIIRE-GRAVVLTSHSMEECEALCTRLAIMVKGAFQCLGT 2153
PRK10789 PRK10789
SmdA family multidrug ABC transporter permease/ATP-binding protein;
5-216 2.39e-16

SmdA family multidrug ABC transporter permease/ATP-binding protein;


Pssm-ID: 182732 [Multi-domain]  Cd Length: 569  Bit Score: 80.14  E-value: 2.39e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   5 NIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPN--QRNIGMVFQ 82
Cdd:PRK10789 317 NIRQFTYPQTDHPALENVNFTLKPGQMLGICGPTGSGKSTLLSLIQRHFDVSEGDIRFHDIPLTKLQLDswRSRLAVVSQ 396

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  83 AYALFPNmTVAQNVSFGlrvsgksrsEIDATVKEMLSLIRLDHLAD---RYP--YQ---------MSGGQQQRVALARAL 148
Cdd:PRK10789 397 TPFLFSD-TVANNIALG---------RPDATQQEIEHVARLASVHDdilRLPqgYDtevgergvmLSGGQKQRISIARAL 466

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 559158796 149 ATKPQVLLLDEPLSALDAKIRISLREEIRAIQQKlgiTTVFVTHDQEEALSISDRIVVMHEGRADQIG 216
Cdd:PRK10789 467 LLNAEILILDDALSAVDGRTEHQILHNLRQWGEG---RTVIISAHRLSALTEASEILVMQHGHIAQRG 531
MK0520 COG2401
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ...
 17-210 9.63e-16

ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];


Pssm-ID: 441957 [Multi-domain]  Cd Length: 222  Bit Score: 75.38  E-value: 9.63e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  17 TVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFE--TPDNGSIEIDgkdvvnlrpnQRNIGmvfqayalfPNMTVAQ 94
Cdd:COG2401   44 YVLRDLNLEIEPGEIVLIVGASGSGKSTLLRLLAGALkgTPVAGCVDVP----------DNQFG---------REASLID 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  95 NVSfglrvsgksrseIDATVKEMLSLIRLDHLAD-----RYPYQMSGGQQQRVALARALATKPQVLLLDEPLSALDAKIR 169
Cdd:COG2401  105 AIG------------RKGDFKDAVELLNAVGLSDavlwlRRFKELSTGQKFRFRLALLLAERPKLLVIDEFCSHLDRQTA 172

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 559158796 170 ISLREEIRAIQQKLGITTVFVTHDQE--EALsISDRIVVMHEG 210
Cdd:COG2401  173 KRVARNLQKLARRAGITLVVATHHYDviDDL-QPDLLIFVGYG 214
MRP_assoc_pro TIGR00957
multi drug resistance-associated protein (MRP); This model describes multi drug ...
 19-217 1.25e-15

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]


Pssm-ID: 188098 [Multi-domain]  Cd Length: 1522  Bit Score: 78.45  E-value: 1.25e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796    19 VHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKdvVNLRPNQrnigmvfqayALFPNMTVAQNVSF 98
Cdd:TIGR00957  654 LNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVHMKGS--VAYVPQQ----------AWIQNDSLRENILF 721

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796    99 GLRVSGKS-RSEIDATVkeMLSLIRLDHLADRYP-----YQMSGGQQQRVALARALATKPQVLLLDEPLSALDAKIRISL 172
Cdd:TIGR00957  722 GKALNEKYyQQVLEACA--LLPDLEILPSGDRTEigekgVNLSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAHVGKHI 799

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 559158796   173 REEIRAIQQKL-GITTVFVTHDQeEALSISDRIVVMHEGRADQIGS 217
Cdd:TIGR00957  800 FEHVIGPEGVLkNKTRILVTHGI-SYLPQVDVIIVMSGGKISEMGS 844
PLN03130 PLN03130
ABC transporter C family member; Provisional
 21-217 1.36e-15

ABC transporter C family member; Provisional


Pssm-ID: 215595 [Multi-domain]  Cd Length: 1622  Bit Score: 78.24  E-value: 1.36e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   21 DFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGfETP--DNGSIEIDGKdvvnlrpnqrnIGMVFQAYALFpNMTVAQNVSF 98
Cdd:PLN03130  635 NINLDVPVGSLVAIVGSTGEGKTSLISAMLG-ELPprSDASVVIRGT-----------VAYVPQVSWIF-NATVRDNILF 701

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   99 GLRV-SGKSRSEIDAT-VKEMLSLI---RLDHLADRyPYQMSGGQQQRVALARALATKPQVLLLDEPLSALDAKI----- 168
Cdd:PLN03130  702 GSPFdPERYERAIDVTaLQHDLDLLpggDLTEIGER-GVNISGGQKQRVSMARAVYSNSDVYIFDDPLSALDAHVgrqvf 780

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 559158796  169 RISLREEIRaiqqklGITTVFVThDQEEALSISDRIVVMHEGRADQIGS 217
Cdd:PLN03130  781 DKCIKDELR------GKTRVLVT-NQLHFLSQVDRIILVHEGMIKEEGT 822
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
 6-193 1.44e-15

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 77.67  E-value: 1.44e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796    6 IKNLKKSFGTN-TVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETpdngsiEIDGKdvVNLRPNqRNIGMVFQAY 84
Cdd:TIGR03719   7 MNRVSKVVPPKkEILKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVDK------DFNGE--ARPQPG-IKVGYLPQEP 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   85 ALFPNMTVAQNVSFGLR-----------VSGK---SRSEIDATVKEMLSLI-------------RLDHLAD--RYP---- 131
Cdd:TIGR03719  78 QLDPTKTVRENVEEGVAeikdaldrfneISAKyaePDADFDKLAAEQAELQeiidaadawdldsQLEIAMDalRCPpwda 157

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 559158796  132 --YQMSGGQQQRVALARALATKPQVLLLDEPLSALDAkirislrEEIRAIQQKL----GiTTVFVTHD 193
Cdd:TIGR03719 158 dvTKLSGGERRRVALCRLLLSKPDMLLLDEPTNHLDA-------ESVAWLERHLqeypG-TVVAVTHD 217
PRK15064 PRK15064
ABC transporter ATP-binding protein; Provisional
 4-215 1.91e-15

ABC transporter ATP-binding protein; Provisional


Pssm-ID: 237894 [Multi-domain]  Cd Length: 530  Bit Score: 77.24  E-value: 1.91e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKdvvnlrpnqRNIGMVFQ- 82
Cdd:PRK15064 320 LEVENLTKGFDNGPLFKNLNLLLEAGERLAIIGENGVGKTTLLRTLVGELEPDSGTVKWSEN---------ANIGYYAQd 390

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  83 AYALFPN-MTVAQNVSfglrvSGKSRSEIDATVKEMLSliRLDHLADRYPYQ---MSGGQQQRVALARALATKPQVLLLD 158
Cdd:PRK15064 391 HAYDFENdLTLFDWMS-----QWRQEGDDEQAVRGTLG--RLLFSQDDIKKSvkvLSGGEKGRMLFGKLMMQKPNVLVMD 463

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 159 EPLSALDAkirislrEEIRAIQQKLGI---TTVFVTHDQEEALSISDRIVvmhEGRADQI 215
Cdd:PRK15064 464 EPTNHMDM-------ESIESLNMALEKyegTLIFVSHDREFVSSLATRII---EITPDGV 513
PLN03211 PLN03211
ABC transporter G-25; Provisional
 6-211 2.23e-15

ABC transporter G-25; Provisional


Pssm-ID: 215634 [Multi-domain]  Cd Length: 659  Bit Score: 77.23  E-value: 2.23e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   6 IKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDN--GSIEIDGKDVVnlRPNQRNIGMVFQA 83
Cdd:PLN03211  71 ISDETRQIQERTILNGVTGMASPGEILAVLGPSGSGKSTLLNALAGRIQGNNftGTILANNRKPT--KQILKRTGFVTQD 148

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  84 YALFPNMTVAQNVSFG--LRV----SGKSRSEIDATVKEMLSLIRLDH--LADRYPYQMSGGQQQRVALARALATKPQVL 155
Cdd:PLN03211 149 DILYPHLTVRETLVFCslLRLpkslTKQEKILVAESVISELGLTKCENtiIGNSFIRGISGGERKRVSIAHEMLINPSLL 228

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 559158796 156 LLDEPLSALDAKIRISLREEIRAIQQKlGITTVFVTHD-QEEALSISDRIVVMHEGR 211
Cdd:PLN03211 229 ILDEPTSGLDATAAYRLVLTLGSLAQK-GKTIVTSMHQpSSRVYQMFDSVLVLSEGR 284
PTZ00265 PTZ00265
multidrug resistance protein (mdr1); Provisional
 56-217 2.35e-15

multidrug resistance protein (mdr1); Provisional


Pssm-ID: 240339 [Multi-domain]  Cd Length: 1466  Bit Score: 77.38  E-value: 2.35e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   56 DNGSIEIDGKDVV--NLRPNQRNIGMVFQAYALFpNMTVAQNVSFGLRvsgksrseiDAT---VKEMLSLIRLDH----L 126
Cdd:PTZ00265 1275 NSGKILLDGVDICdyNLKDLRNLFSIVSQEPMLF-NMSIYENIKFGKE---------DATredVKRACKFAAIDEfiesL 1344

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  127 ADRY-----PY--QMSGGQQQRVALARALATKPQVLLLDEPLSALDAKIRISLREEIRAIQQKLGITTVFVTHdQEEALS 199
Cdd:PTZ00265 1345 PNKYdtnvgPYgkSLSGGQKQRIAIARALLREPKILLLDEATSSLDSNSEKLIEKTIVDIKDKADKTIITIAH-RIASIK 1423

                         170
                  ....*....|....*...
gi 559158796  200 ISDRIVVMHEgrADQIGS 217
Cdd:PTZ00265 1424 RSDKIVVFNN--PDRTGS 1439
PRK13543 PRK13543
heme ABC exporter ATP-binding protein CcmA;
21-205 4.27e-15

heme ABC exporter ATP-binding protein CcmA;


Pssm-ID: 184129 [Multi-domain]  Cd Length: 214  Bit Score: 73.34  E-value: 4.27e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  21 DFNLAVGKGEFVSflGPSGCGKTTVLRMIAGFETPDNGSIEIDGKdvvnlrPNQRNIGMVFQAY-----ALFPNMTVAQN 95
Cdd:PRK13543  31 DFHVDAGEALLVQ--GDNGAGKTTLLRVLAGLLHVESGQIQIDGK------TATRGDRSRFMAYlghlpGLKADLSTLEN 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  96 VSFGLRVSGKSRSEIDATVkemLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSALDAKiRISLREE 175
Cdd:PRK13543 103 LHFLCGLHGRRAKQMPGSA---LAIVGLAGYEDTLVRQLSAGQKKRLALARLWLSPAPLWLLDEPYANLDLE-GITLVNR 178

                        170       180       190
                 ....*....|....*....|....*....|
gi 559158796 176 IRAIQQKLGITTVFVTHDQEEALSISDRIV 205
Cdd:PRK13543 179 MISAHLRGGGAALVTTHGAYAAPPVRTRML 208
PRK03695 PRK03695
vitamin B12-transporter ATPase; Provisional
 22-218 5.81e-15

vitamin B12-transporter ATPase; Provisional


Pssm-ID: 235150 [Multi-domain]  Cd Length: 248  Bit Score: 73.43  E-value: 5.81e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  22 FNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFeTPDNGSIEIDGKDVVNLRPN---QRNIGMVFQAYALFpNMTVAQNVSf 98
Cdd:PRK03695  15 LSAEVRAGEILHLVGPNGAGKSTLLARMAGL-LPGSGSIQFAGQPLEAWSAAelaRHRAYLSQQQTPPF-AMPVFQYLT- 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  99 gLRVSGKSRSEIDATVKEML-SLIRLDHLADRYPYQMSGGQQQRVALARAL-----ATKP--QVLLLDEPLSALDAKIRI 170
Cdd:PRK03695  92 -LHQPDKTRTEAVASALNEVaEALGLDDKLGRSVNQLSGGEWQRVRLAAVVlqvwpDINPagQLLLLDEPMNSLDVAQQA 170

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 559158796 171 SLREEIRAIQQkLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGSP 218
Cdd:PRK03695 171 ALDRLLSELCQ-QGIAVVMSSHDLNHTLRHADRVWLLKQGKLLASGRR 217
ycf16 CHL00131
sulfate ABC transporter protein; Validated
 4-217 6.79e-15

sulfate ABC transporter protein; Validated


Pssm-ID: 214372 [Multi-domain]  Cd Length: 252  Bit Score: 73.52  E-value: 6.79e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFetPD----NGSIEIDGKDVVNLRPNQRN--- 76
Cdd:CHL00131   8 LEIKNLHASVNENEILKGLNLSINKGEIHAIMGPNGSGKSTLSKVIAGH--PAykilEGDILFKGESILDLEPEERAhlg 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  77 IGMVFQAYALFPNMTvaqNVSFgLRVSGKSR------SEIDA-----TVKEMLSLIRLD-HLADRYPYQ-MSGGQQQRVA 143
Cdd:CHL00131  86 IFLAFQYPIEIPGVS---NADF-LRLAYNSKrkfqglPELDPlefleIINEKLKLVGMDpSFLSRNVNEgFSGGEKKRNE 161

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 559158796 144 LARALATKPQVLLLDEPLSALDAKIRISLREEIRAIQQKlGITTVFVTHDQEEALSIS-DRIVVMHEGRADQIGS 217
Cdd:CHL00131 162 ILQMALLDSELAILDETDSGLDIDALKIIAEGINKLMTS-ENSIILITHYQRLLDYIKpDYVHVMQNGKIIKTGD 235
PLN03232 PLN03232
ABC transporter C family member; Provisional
 15-217 1.25e-14

ABC transporter C family member; Provisional


Pssm-ID: 215640 [Multi-domain]  Cd Length: 1495  Bit Score: 75.40  E-value: 1.25e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   15 TNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETP-DNGSIEIDGkdvvnlrpnqrNIGMVFQAYALFpNMTVA 93
Cdd:PLN03232  629 SKPTLSDINLEIPVGSLVAIVGGTGEGKTSLISAMLGELSHaETSSVVIRG-----------SVAYVPQVSWIF-NATVR 696

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   94 QNVSFGLRV-SGKSRSEIDATVkemlslirLDHLADRYP-----------YQMSGGQQQRVALARALATKPQVLLLDEPL 161
Cdd:PLN03232  697 ENILFGSDFeSERYWRAIDVTA--------LQHDLDLLPgrdlteigergVNISGGQKQRVSMARAVYSNSDIYIFDDPL 768

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 559158796  162 SALDAKI-----RISLREEIRaiqqklGITTVFVThDQEEALSISDRIVVMHEGRADQIGS 217
Cdd:PLN03232  769 SALDAHVahqvfDSCMKDELK------GKTRVLVT-NQLHFLPLMDRIILVSEGMIKEEGT 822
PTZ00265 PTZ00265
multidrug resistance protein (mdr1); Provisional
 4-192 1.33e-14

multidrug resistance protein (mdr1); Provisional


Pssm-ID: 240339 [Multi-domain]  Cd Length: 1466  Bit Score: 75.07  E-value: 1.33e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796    4 LNIKNLKKSFGTNTVVH---DFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDG----KDvVNLRPNQRN 76
Cdd:PTZ00265  383 IQFKNVRFHYDTRKDVEiykDLNFTLTEGKTYAFVGESGCGKSTILKLIERLYDPTEGDIIINDshnlKD-INLKWWRSK 461

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   77 IGMVFQAYALFPNmTVAQNVSFGL--------------------------RVSGKSR----------------------- 107
Cdd:PTZ00265  462 IGVVSQDPLLFSN-SIKNNIKYSLyslkdlealsnyynedgndsqenknkRNSCRAKcagdlndmsnttdsneliemrkn 540

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  108 ------SEIDATVKEMLSLIRLDHLADRY-------PYQMSGGQQQRVALARALATKPQVLLLDEPLSALDAKIRISLRE 174
Cdd:PTZ00265  541 yqtikdSEVVDVSKKVLIHDFVSALPDKYetlvgsnASKLSGGQKQRISIARAIIRNPKILILDEATSSLDNKSEYLVQK 620

                         250
                  ....*....|....*...
gi 559158796  175 EIRAIQQKLGITTVFVTH 192
Cdd:PTZ00265  621 TINNLKGNENRITIIIAH 638
3a01205 TIGR00956
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
 29-215 1.50e-14

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273362 [Multi-domain]  Cd Length: 1394  Bit Score: 75.15  E-value: 1.50e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796    29 GEFVSFLGPSGCGKTTVLRMIA----GFETPDNGSIEIDGKDVVNLRPNQRniGMVF---QAYALFPNMTVAQNVSF--- 98
Cdd:TIGR00956   87 GELTVVLGRPGSGCSTLLKTIAsntdGFHIGVEGVITYDGITPEEIKKHYR--GDVVynaETDVHFPHLTVGETLDFaar 164

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796    99 ----GLRVSGKSRSEIDATVKEM-LSLIRLDH-----LADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSALDAKI 168
Cdd:TIGR00956  165 cktpQNRPDGVSREEYAKHIADVyMATYGLSHtrntkVGNDFVRGVSGGERKRVSIAEASLGGAKIQCWDNATRGLDSAT 244

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 559158796   169 RIslrEEIRAIQQKLGI--TTVFVTHDQ--EEALSISDRIVVMHEGRadQI 215
Cdd:TIGR00956  245 AL---EFIRALKTSANIldTTPLVAIYQcsQDAYELFDKVIVLYEGY--QI 290
ABCG_PDR_domain2 cd03232
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ...
 14-210 1.44e-13

Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213199 [Multi-domain]  Cd Length: 192  Bit Score: 68.42  E-value: 1.44e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  14 GTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETpdNGSIEidGKDVVNLRPN----QRNIGMVFQAYALFPN 89
Cdd:cd03232   18 GKRQLLNNISGYVKPGTLTALMGESGAGKTTLLDVLAGRKT--AGVIT--GEILINGRPLdknfQRSTGYVEQQDVHSPN 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  90 MTVAQnvsfGLRVSGKSRSeidatvkemLSLirldhladrypyqmsgGQQQRVALARALATKPQVLLLDEPLSALDAKIR 169
Cdd:cd03232   94 LTVRE----ALRFSALLRG---------LSV----------------EQRKRLTIGVELAAKPSILFLDEPTSGLDSQAA 144

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 559158796 170 ISLreeIRAIqQKLGIT--TVFVTHDQEEALSIS--DRIVVMHEG 210
Cdd:cd03232  145 YNI---VRFL-KKLADSgqAILCTIHQPSASIFEkfDRLLLLKRG 185
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
 35-193 2.39e-13

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 70.92  E-value: 2.39e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  35 LGPSGCGKTTVLRMIAGFETPDNGSieidgkdvVNLRPNQRnIGMVFQAYALFPNMTVAQNVSFGLR-----------VS 103
Cdd:PRK11819  39 LGLNGAGKSTLLRIMAGVDKEFEGE--------ARPAPGIK-VGYLPQEPQLDPEKTVRENVEEGVAevkaaldrfneIY 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 104 GK---SRSEIDATVKEMLSLI-RLDHL--------------ADRYP------YQMSGGQQQRVALARALATKPQVLLLDE 159
Cdd:PRK11819 110 AAyaePDADFDALAAEQGELQeIIDAAdawdldsqleiamdALRCPpwdakvTKLSGGERRRVALCRLLLEKPDMLLLDE 189

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 559158796 160 PLSALDAkirislrEEIRAIQQKL----GiTTVFVTHD 193
Cdd:PRK11819 190 PTNHLDA-------ESVAWLEQFLhdypG-TVVAVTHD 219
PRK11147 PRK11147
ABC transporter ATPase component; Reviewed
 1-205 2.70e-13

ABC transporter ATPase component; Reviewed


Pssm-ID: 236861 [Multi-domain]  Cd Length: 635  Bit Score: 70.75  E-value: 2.70e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   1 MAFLNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDgKDVVNLRPNQ---RNI 77
Cdd:PRK11147   1 MSLISIHGAWLSFSDAPLLDNAELHIEDNERVCLVGRNGAGKSTLMKILNGEVLLDDGRIIYE-QDLIVARLQQdppRNV 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  78 -GMVF---------QAYALFPNMTVAQNVsfGLRVSGKSRSEI---------------DATVKEMLSLIRLDhlADRYPY 132
Cdd:PRK11147  80 eGTVYdfvaegieeQAEYLKRYHDISHLV--ETDPSEKNLNELaklqeqldhhnlwqlENRINEVLAQLGLD--PDAALS 155

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 559158796 133 QMSGGQQQRVALARALATKPQVLLLDEPLSALDAkirislrEEIRAIQQKL----GiTTVFVTHDQEEALSISDRIV 205
Cdd:PRK11147 156 SLSGGWLRKAALGRALVSNPDVLLLDEPTNHLDI-------ETIEWLEGFLktfqG-SIIFISHDRSFIRNMATRIV 224
ABCC_SUR1_N cd03290
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ...
 12-210 5.62e-13

ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.


Pssm-ID: 213257 [Multi-domain]  Cd Length: 218  Bit Score: 67.36  E-value: 5.62e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  12 SFGTN-TVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVN---LRPNQRNIGMVfqAYA-- 85
Cdd:cd03290    9 SWGSGlATLSNINIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVHWSNKNESEpsfEATRSRNRYSV--AYAaq 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  86 --LFPNMTVAQNVSFGLRVSgKSRSEidaTVKEMLSL---IRLDHLADRYP-----YQMSGGQQQRVALARALATKPQVL 155
Cdd:cd03290   87 kpWLLNATVEENITFGSPFN-KQRYK---AVTDACSLqpdIDLLPFGDQTEigergINLSGGQRQRICVARALYQNTNIV 162

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 559158796 156 LLDEPLSALDAKIRISLREE-IRAIQQKLGITTVFVTHdQEEALSISDRIVVMHEG 210
Cdd:cd03290  163 FLDDPFSALDIHLSDHLMQEgILKFLQDDKRTLVLVTH-KLQYLPHADWIIAMKDG 217
PRK13541 PRK13541
cytochrome c biogenesis protein CcmA; Provisional
 16-169 5.93e-13

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 184128 [Multi-domain]  Cd Length: 195  Bit Score: 66.82  E-value: 5.93e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  16 NTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNL-RPNQRNIGmvfQAYALFPNMTVAQ 94
Cdd:PRK13541  13 QKNLFDLSITFLPSAITYIKGANGCGKSSLLRMIAGIMQPSSGNIYYKNCNINNIaKPYCTYIG---HNLGLKLEMTVFE 89

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 559158796  95 NVSFGLRVSGKSrseidATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSALDAKIR 169
Cdd:PRK13541  90 NLKFWSEIYNSA-----ETLYAAIHYFKLHDLLDEKCYSLSSGMQKIVAIARLIACQSDLWLLDEVETNLSKENR 159
ABCC_CFTR1 cd03291
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ...
 16-210 6.83e-13

ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.


Pssm-ID: 213258 [Multi-domain]  Cd Length: 282  Bit Score: 67.96  E-value: 6.83e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  16 NTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKdvvnlrpnqrnIGMVFQAYALFPNmTVAQN 95
Cdd:cd03291   50 APVLKNINLKIEKGEMLAITGSTGSGKTSLLMLILGELEPSEGKIKHSGR-----------ISFSSQFSWIMPG-TIKEN 117

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  96 VSFGLrvsgksrSEIDATVKEMLSLIRLDHLADRYPYQ-----------MSGGQQQRVALARALATKPQVLLLDEPLSAL 164
Cdd:cd03291  118 IIFGV-------SYDEYRYKSVVKACQLEEDITKFPEKdntvlgeggitLSGGQRARISLARAVYKDADLYLLDSPFGYL 190

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 559158796 165 DakirISLREEI------RAIQQKlgiTTVFVTHDQEEaLSISDRIVVMHEG 210
Cdd:cd03291  191 D----VFTEKEIfescvcKLMANK---TRILVTSKMEH-LKKADKILILHEG 234
PRK15056 PRK15056
manganese/iron ABC transporter ATP-binding protein;
16-193 7.73e-13

manganese/iron ABC transporter ATP-binding protein;


Pssm-ID: 185016 [Multi-domain]  Cd Length: 272  Bit Score: 67.99  E-value: 7.73e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  16 NTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVvNLRPNQRNIGMVFQAYAL---FPnMTV 92
Cdd:PRK15056  20 HTALRDASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLASGKISILGQPT-RQALQKNLVAYVPQSEEVdwsFP-VLV 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  93 AQNVSFGL--------RVSGKSRSEIDAtvkemlSLIRLDHLADRYPY--QMSGGQQQRVALARALATKPQVLLLDEPLS 162
Cdd:PRK15056  98 EDVVMMGRyghmgwlrRAKKRDRQIVTA------ALARVDMVEFRHRQigELSGGQKKRVFLARAIAQQGQVILLDEPFT 171

                        170       180       190
                 ....*....|....*....|....*....|....
gi 559158796 163 ALDAKIR---ISLREEIRAiqqkLGITTVFVTHD 193
Cdd:PRK15056 172 GVDVKTEariISLLRELRD----EGKTMLVSTHN 201
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
 22-208 7.95e-13

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 69.43  E-value: 7.95e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  22 FNLAV-GKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDG--KDVVnlrpnQRNIGMVFQAYalFP-----NMTVA 93
Cdd:COG1245   91 YGLPVpKKGKVTGILGPNGIGKSTALKILSGELKPNLGDYDEEPswDEVL-----KRFRGTELQDY--FKklangEIKVA 163

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  94 ---QNVSF-GLRVSGKSRSEIDAT-----VKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSAL 164
Cdd:COG1245  164 hkpQYVDLiPKVFKGTVRELLEKVdergkLDELAEKLGLENILDRDISELSGGELQRVAIAAALLRDADFYFFDEPSSYL 243

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 559158796 165 DAKIRISLREEIRAIQQKlGITTVFVTHDqeeaLSI----SDRIVVMH 208
Cdd:COG1245  244 DIYQRLNVARLIRELAEE-GKYVLVVEHD----LAIldylADYVHILY 286
CFTR_protein TIGR01271
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...
 18-210 8.34e-13

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]


Pssm-ID: 273530 [Multi-domain]  Cd Length: 1490  Bit Score: 69.55  E-value: 8.34e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796    18 VVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKdvvnlrpnqrnIGMVFQAYALFPNmTVAQNVS 97
Cdd:TIGR01271  441 VLKNISFKLEKGQLLAVAGSTGSGKSSLLMMIMGELEPSEGKIKHSGR-----------ISFSPQTSWIMPG-TIKDNII 508

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796    98 FGLRVSG-KSRSEIDA-TVKEMLSLIRLDhlaDRYPY-----QMSGGQQQRVALARALATKPQVLLLDEPLSALDakirI 170
Cdd:TIGR01271  509 FGLSYDEyRYTSVIKAcQLEEDIALFPEK---DKTVLgeggiTLSGGQRARISLARAVYKDADLYLLDSPFTHLD----V 581

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|..
gi 559158796   171 SLREEI--RAIQQKLGITTVFVTHDQEEALSISDRIVVMHEG 210
Cdd:TIGR01271  582 VTEKEIfeSCLCKLMSNKTRILVTSKLEHLKKADKILLLHEG 623
ABC_RNaseL_inhibitor cd03222
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ...
 26-208 1.01e-12

ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213189 [Multi-domain]  Cd Length: 177  Bit Score: 65.67  E-value: 1.01e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  26 VGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVnLRPnqrnigmvfqayalfpnmtvaQNVSfglrvsgk 105
Cdd:cd03222   22 VKEGEVIGIVGPNGTGKTTAVKILAGQLIPNGDNDEWDGITPV-YKP---------------------QYID-------- 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 106 srseidatvkemlslirldhladrypyqMSGGQQQRVALARALATKPQVLLLDEPLSALDAKIRISLREEIRAIQQKLGI 185
Cdd:cd03222   72 ----------------------------LSGGELQRVAIAAALLRNATFYLFDEPSAYLDIEQRLNAARAIRRLSEEGKK 123

                        170       180
                 ....*....|....*....|...
gi 559158796 186 TTVFVTHDQEEALSISDRIVVMH 208
Cdd:cd03222  124 TALVVEHDLAVLDYLSDRIHVFE 146
PRK11147 PRK11147
ABC transporter ATPase component; Reviewed
 6-195 1.18e-12

ABC transporter ATPase component; Reviewed


Pssm-ID: 236861 [Multi-domain]  Cd Length: 635  Bit Score: 68.82  E-value: 1.18e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   6 IKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVnlrpnqrnigmvfqAY- 84
Cdd:PRK11147 322 MENVNYQIDGKQLVKDFSAQVQRGDKIALIGPNGCGKTTLLKLMLGQLQADSGRIHCGTKLEV--------------AYf 387

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  85 -----ALFPNMTVAQNVSFG---LRVSGKSRSEidatvkemlslirLDHLAD--------RYPYQ-MSGGQQQRVALARa 147
Cdd:PRK11147 388 dqhraELDPEKTVMDNLAEGkqeVMVNGRPRHV-------------LGYLQDflfhpkraMTPVKaLSGGERNRLLLAR- 453

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 559158796 148 LATKPQVLL-LDEPLSALDAKIrISLREEIRAIQQKlgiTTVFVTHDQE 195
Cdd:PRK11147 454 LFLKPSNLLiLDEPTNDLDVET-LELLEELLDSYQG---TVLLVSHDRQ 498
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
4-215 1.23e-12

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 68.22  E-value: 1.23e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVlRMIAGFETPDNGSIEIDGKD-VVNLRPNQRNIGMVFQ 82
Cdd:NF000106  14 VEVRGLVKHFGEVKAVDGVDLDVREGTVLGVLGP*GAA**RG-ALPAHV*GPDAGRRPWRF*TwCANRRALRRTIG*HRP 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  83 A-YALFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPL 161
Cdd:NF000106  93 Vr*GRRESFSGRENLYMIGR*LDLSRKDARARADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPT 172

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 162 SALDAKIRISLREEIRAIQQKlGITTVFVTHDQEEA------LSISDRIVVMHEGRADQI 215
Cdd:NF000106 173 TGLDPRTRNEVWDEVRSMVRD-GATVLLTTQYMEEAeqlaheLTVIDRGRVIADGKVDEL 231
ABC_RNaseL_inhibitor_domain1 cd03236
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
 29-208 1.26e-12

The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213203 [Multi-domain]  Cd Length: 255  Bit Score: 67.01  E-value: 1.26e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  29 GEFVSFLGPSGCGKTTVLRMIAGFETPDNGSI--EIDGKDVVN-------------LRPNQRNIGMVFQAYALFPNmtva 93
Cdd:cd03236   26 GQVLGLVGPNGIGKSTALKILAGKLKPNLGKFddPPDWDEILDefrgselqnyftkLLEGDVKVIVKPQYVDLIPK---- 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  94 qnvsfglRVSGKSRSEIDAT-----VKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSALDAKI 168
Cdd:cd03236  102 -------AVKGKVGELLKKKdergkLDELVDQLELRHVLDRNIDQLSGGELQRVAIAAALARDADFYFFDEPSSYLDIKQ 174

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 559158796 169 RISLREEIRAIQQKlGITTVFVTHDqeeaLSI----SDRIVVMH 208
Cdd:cd03236  175 RLNAARLIRELAED-DNYVLVVEHD----LAVldylSDYIHCLY 213
PLN03232 PLN03232
ABC transporter C family member; Provisional
 18-229 1.30e-12

ABC transporter C family member; Provisional


Pssm-ID: 215640 [Multi-domain]  Cd Length: 1495  Bit Score: 69.23  E-value: 1.30e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   18 VVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVN--LRPNQRNIGMVFQAYALFpnmtvAQN 95
Cdd:PLN03232 1251 VLHGLSFFVSPSEKVGVVGRTGAGKSSMLNALFRIVELEKGRIMIDDCDVAKfgLTDLRRVLSIIPQSPVLF-----SGT 1325

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   96 VSFGLRVSGKSRseiDATVKEMLSLIRLDHLADRYPYQM-----------SGGQQQRVALARALATKPQVLLLDEPLSAL 164
Cdd:PLN03232 1326 VRFNIDPFSEHN---DADLWEALERAHIKDVIDRNPFGLdaevseggenfSVGQRQLLSLARALLRRSKILVLDEATASV 1402

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 559158796  165 DAK----IRISLREEIRAiqqklgITTVFVTHDQEEALSiSDRIVVMHEGRADQIGSPFDIYNRPASRF 229
Cdd:PLN03232 1403 DVRtdslIQRTIREEFKS------CTMLVIAHRLNTIID-CDKILVLSSGQVLEYDSPQELLSRDTSAF 1464
GguA NF040905
sugar ABC transporter ATP-binding protein;
4-211 5.09e-12

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 66.74  E-value: 5.09e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAG------FEtpdnGSIEIDGKdVVNLR----PN 73
Cdd:NF040905   2 LEMRGITKTFPGVKALDDVNLSVREGEIHALCGENGAGKSTLMKVLSGvyphgsYE----GEILFDGE-VCRFKdirdSE 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  74 QRNIGMVFQAYALFPNMTVAQNVSFGLRVSGK---SRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALAT 150
Cdd:NF040905  77 ALGIVIIHQELALIPYLSIAENIFLGNERAKRgviDWNETNRRARELLAKVGLDESPDTLVTDIGVGKQQLVEIAKALSK 156

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 559158796 151 KPQVLLLDEPLSALDAKIRISLREEIRAIQQKlGITTVFVTHDQEEALSISDRIVVMHEGR 211
Cdd:NF040905 157 DVKLLILDEPTAALNEEDSAALLDLLLELKAQ-GITSIIISHKLNEIRRVADSITVLRDGR 216
GguA NF040905
sugar ABC transporter ATP-binding protein;
18-211 5.52e-12

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 66.74  E-value: 5.52e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  18 VVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAG--FETPDNGSIEIDGKDVvNLRPNQRNI--GMVF-----QAYALFP 88
Cdd:NF040905 275 VVDDVSLNVRRGEIVGIAGLMGAGRTELAMSVFGrsYGRNISGTVFKDGKEV-DVSTVSDAIdaGLAYvtedrKGYGLNL 353

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  89 NMTVAQNVSF-GL-RVSgkSRSEIDAtVKEMLSlirldhlADRYPYQM--------------SGGQQQRVALARALATKP 152
Cdd:NF040905 354 IDDIKRNITLaNLgKVS--RRGVIDE-NEEIKV-------AEEYRKKMniktpsvfqkvgnlSGGNQQKVVLSKWLFTDP 423

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 559158796 153 QVLLLDEPLSALD--AKIrislreEIRAIQQKL---GITTVFVTHDQEEALSISDRIVVMHEGR 211
Cdd:NF040905 424 DVLILDEPTRGIDvgAKY------EIYTIINELaaeGKGVIVISSELPELLGMCDRIYVMNEGR 481
TOBE_2 pfam08402
TOBE domain; The TOBE domain (Transport-associated OB) always occurs as a dimer as the ...
 276-351 6.14e-12

TOBE domain; The TOBE domain (Transport-associated OB) always occurs as a dimer as the C-terminal strand of each domain is supplied by the partner. Probably involved in the recognition of small ligands such as molybdenum and sulphate. Found in ABC transporters immediately after the ATPase domain. In this family a strong RPE motif is found at the presumed N-terminus of the domain.


Pssm-ID: 462465 [Multi-domain]  Cd Length: 73  Bit Score: 60.33  E-value: 6.14e-12
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 559158796  276 LALRPEAVSLEARkshDTSLEATIDDVHFLGSVIRTRVILGKNRLSFDTFNDPTHPPPQRGDKVTVHFASHDLLVL 351
Cdd:pfam08402   1 LAIRPEKIRLAAA---ANGLSGTVTDVEYLGDHTRYHVELAGGEELVVRVPNAHARPPAPGDRVGLGWDPEDAHVL 73
PTZ00243 PTZ00243
ABC transporter; Provisional
 18-220 6.52e-12

ABC transporter; Provisional


Pssm-ID: 240327 [Multi-domain]  Cd Length: 1560  Bit Score: 67.11  E-value: 6.52e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   18 VVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGfetpdngSIEIDGKDVVNlrpnQRNIGMVFQAyALFPNMTVAQNVS 97
Cdd:PTZ00243  675 LLRDVSVSVPRGKLTVVLGATGSGKSTLLQSLLS-------QFEISEGRVWA----ERSIAYVPQQ-AWIMNATVRGNIL 742

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   98 F-----GLRVSGKSR-SEIDATVKEMLSliRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSALDAKIRIS 171
Cdd:PTZ00243  743 FfdeedAARLADAVRvSQLEADLAQLGG--GLETEIGEKGVNLSGGQKARVSLARAVYANRDVYLLDDPLSALDAHVGER 820

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 559158796  172 LREEIraIQQKL-GITTVFVTHdQEEALSISDRIVVMHEGRADQIGSPFD 220
Cdd:PTZ00243  821 VVEEC--FLGALaGKTRVLATH-QVHVVPRADYVVALGDGRVEFSGSSAD 867
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 28-207 7.60e-12

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 62.39  E-value: 7.60e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796    28 KGEFVSFLGPSGCGKTTVLRMIAGFETPDNGS-IEIDGkdvvnlrpnqrnigmvfqayalfpnmtvaqnvsfglrvsgks 106
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPGGGvIYIDG------------------------------------------ 38

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   107 rseidATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSALDAKIRISLREEIRA-----IQQ 181
Cdd:smart00382  39 -----EDILEEVLDQLLLIIVGGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLLLLEELrllllLKS 113

                          170       180       190
                   ....*....|....*....|....*....|.
gi 559158796   182 KLGITTVFVTHDQEEALS-----ISDRIVVM 207
Cdd:smart00382 114 EKNLTVILTTNDEKDLGPallrrRFDRRIVL 144
sufC PRK09580
cysteine desulfurase ATPase component; Reviewed
 4-211 1.02e-11

cysteine desulfurase ATPase component; Reviewed


Pssm-ID: 181965 [Multi-domain]  Cd Length: 248  Bit Score: 64.04  E-value: 1.02e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFE--TPDNGSIEIDGKDVVNLRPNQRNIGMVF 81
Cdd:PRK09580   2 LSIKDLHVSVEDKAILRGLNLEVRPGEVHAIMGPNGSGKSTLSATLAGREdyEVTGGTVEFKGKDLLELSPEDRAGEGIF 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  82 QAYAlFPNMTVAQNVSFGLRVSGKS-----------RSEIDATVKEMLSLIRL--DHLADRYPYQMSGGQQQRVALARAL 148
Cdd:PRK09580  82 MAFQ-YPVEIPGVSNQFFLQTALNAvrsyrgqepldRFDFQDLMEEKIALLKMpeDLLTRSVNVGFSGGEKKRNDILQMA 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 559158796 149 ATKPQVLLLDEPLSALDAK-IRI------SLREEIRAIqqklgittVFVTHDQEEALSIS-DRIVVMHEGR 211
Cdd:PRK09580 161 VLEPELCILDESDSGLDIDaLKIvadgvnSLRDGKRSF--------IIVTHYQRILDYIKpDYVHVLYQGR 223
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
6-231 3.13e-11

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 64.76  E-value: 3.13e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   6 IKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQRNIGMVfqAYA 85
Cdd:NF033858   4 LEGVSHRYGKTVALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRVEVLGGDMADARHRRAVCPRI--AYM 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  86 -------LFPNMTVAQNVSFGLRVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLD 158
Cdd:NF033858  82 pqglgknLYPTLSVFENLDFFGRLFGQDAAERRRRIDELLRATGLAPFADRPAGKLSGGMKQKLGLCCALIHDPDLLILD 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 159 EPLSALDAKIRI---SLREEIRAiqQKLGITTVFVTHDQEEALSIsDRIVVMHEGRADQIGSPFDIYNRPASR-----FV 230
Cdd:NF033858 162 EPTTGVDPLSRRqfwELIDRIRA--ERPGMSVLVATAYMEEAERF-DWLVAMDAGRVLATGTPAELLARTGADtleaaFI 238


                 .
gi 559158796 231 A 231
Cdd:NF033858 239 A 239
3a01203 TIGR00954
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, ...
 18-192 3.29e-11

Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 273360 [Multi-domain]  Cd Length: 659  Bit Score: 64.38  E-value: 3.29e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   18 VVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQRNIGM-VFQAYALFPnMTVAQNV 96
Cdd:TIGR00954 467 LIESLSFEVPSGNNLLICGPNGCGKSSLFRILGELWPVYGGRLTKPAKGKLFYVPQRPYMTLgTLRDQIIYP-DSSEDMK 545

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   97 SFGLRvsgksrseiDATVKEMLSLIRLDHLADR---------YPYQMSGGQQQRVALARALATKPQVLLLDEPLSAldak 167
Cdd:TIGR00954 546 RRGLS---------DKDLEQILDNVQLTHILEReggwsavqdWMDVLSGGEKQRIAMARLFYHKPQFAILDECTSA---- 612

                         170       180
                  ....*....|....*....|....*
gi 559158796  168 IRISLREEIRAIQQKLGITTVFVTH 192
Cdd:TIGR00954 613 VSVDVEGYMYRLCREFGITLFSVSH 637
PRK10982 PRK10982
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
 19-215 3.31e-11

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional


Pssm-ID: 182880 [Multi-domain]  Cd Length: 491  Bit Score: 64.37  E-value: 3.31e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  19 VHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQR-NIGMVF-----QAYALFPNMTV 92
Cdd:PRK10982 264 IRDVSFDLHKGEILGIAGLVGAKRTDIVETLFGIREKSAGTITLHGKKINNHNANEAiNHGFALvteerRSTGIYAYLDI 343

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  93 AQNV----------SFGLRVSGKSRSEIDATVKEMlsliRLDHLADRYPY-QMSGGQQQRVALARALATKPQVLLLDEPL 161
Cdd:PRK10982 344 GFNSlisnirnyknKVGLLDNSRMKSDTQWVIDSM----RVKTPGHRTQIgSLSGGNQQKVIIGRWLLTQPEILMLDEPT 419

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 559158796 162 SALDAKIRISLREEIRAIQQK-LGIttVFVTHDQEEALSISDRIVVMHEGRADQI 215
Cdd:PRK10982 420 RGIDVGAKFEIYQLIAELAKKdKGI--IIISSEMPELLGITDRILVMSNGLVAGI 472
PRK10982 PRK10982
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
 6-211 3.62e-11

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional


Pssm-ID: 182880 [Multi-domain]  Cd Length: 491  Bit Score: 63.98  E-value: 3.62e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   6 IKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVvNLRPN----QRNIGMVF 81
Cdd:PRK10982   1 MSNISKSFPGVKALDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGSILFQGKEI-DFKSSkealENGISMVH 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  82 QAYALFPNMTVAQNVSFG------LRVS-GKSRSEIDATVKEM-LSLIRLDHLADrypyqMSGGQQQRVALARALATKPQ 153
Cdd:PRK10982  80 QELNLVLQRSVMDNMWLGryptkgMFVDqDKMYRDTKAIFDELdIDIDPRAKVAT-----LSVSQMQMIEIAKAFSYNAK 154

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 559158796 154 VLLLDEPLSALDAKIRISLREEIRAIQQKlGITTVFVTHDQEEALSISDRIVVMHEGR 211
Cdd:PRK10982 155 IVIMDEPTSSLTEKEVNHLFTIIRKLKER-GCGIVYISHKMEEIFQLCDEITILRDGQ 211
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
28-207 6.55e-11

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 63.29  E-value: 6.55e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  28 KGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDG--KDVVnlrpnQRNIGMVFQAYalFPNmtVAQNvsfGLRVSGK 105
Cdd:PRK13409  98 EGKVTGILGPNGIGKTTAVKILSGELIPNLGDYEEEPswDEVL-----KRFRGTELQNY--FKK--LYNG---EIKVVHK 165

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 106 SRsEIDA-------TVKEML-------------SLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSALD 165
Cdd:PRK13409 166 PQ-YVDLipkvfkgKVRELLkkvdergkldevvERLGLENILDRDISELSGGELQRVAIAAALLRDADFYFFDEPTSYLD 244

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 559158796 166 AKIRISLREEIRAIQQklGITTVFVTHDqeeaLSI----SDRIVVM 207
Cdd:PRK13409 245 IRQRLNVARLIRELAE--GKYVLVVEHD----LAVldylADNVHIA 284
PRK10522 PRK10522
multidrug transporter membrane component/ATP-binding component; Provisional
 23-211 8.52e-11

multidrug transporter membrane component/ATP-binding component; Provisional


Pssm-ID: 236707 [Multi-domain]  Cd Length: 547  Bit Score: 63.07  E-value: 8.52e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  23 NLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPN--QRNIGMVFQAYALFPnmtvaqnvsfgl 100
Cdd:PRK10522 343 NLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEILLDGKPVTAEQPEdyRKLFSAVFTDFHLFD------------ 410

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 101 RVSGKSRSEID-ATVKEMLSLIRLDH--------LADrypYQMSGGQQQRVALARALATKPQVLLLDEPLSALDAKIRIS 171
Cdd:PRK10522 411 QLLGPEGKPANpALVEKWLERLKMAHkleledgrISN---LKLSKGQKKRLALLLALAEERDILLLDEWAADQDPHFRRE 487

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 559158796 172 LREEIRAIQQKLGITTVFVTHDqEEALSISDRIVVMHEGR 211
Cdd:PRK10522 488 FYQVLLPLLQEMGKTIFAISHD-DHYFIHADRLLEMRNGQ 526
PvdE COG4615
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion ...
 22-211 9.03e-11

ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion transport and metabolism];


Pssm-ID: 443659 [Multi-domain]  Cd Length: 547  Bit Score: 62.89  E-value: 9.03e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  22 FNLAVGKGEFVsFL-GPSGCGKTTVLRMIAGFETPDNGSIEIDGKDV--VNLRPNQRNIGMVFQAYALFPnmtvaqnvsf 98
Cdd:COG4615  351 IDLTIRRGELV-FIvGGNGSGKSTLAKLLTGLYRPESGEILLDGQPVtaDNREAYRQLFSAVFSDFHLFD---------- 419

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  99 glRVSGKSRSEIDATVKEMLSLIRLDH--------LADRypyQMSGGQQQRVALARALATKPQVLLLDE------Plsal 164
Cdd:COG4615  420 --RLLGLDGEADPARARELLERLELDHkvsvedgrFSTT---DLSQGQRKRLALLVALLEDRPILVFDEwaadqdP---- 490

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 559158796 165 dakiriSLRE--------EIRAiqqkLGITTVFVTHDqEEALSISDRIVVMHEGR 211
Cdd:COG4615  491 ------EFRRvfytellpELKA----RGKTVIAISHD-DRYFDLADRVLKMDYGK 534
CFTR_protein TIGR01271
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...
 4-217 1.39e-10

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]


Pssm-ID: 273530 [Multi-domain]  Cd Length: 1490  Bit Score: 63.01  E-value: 1.39e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796     4 LNIKNL--KKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDnGSIEIDGK--DVVNLRPNQRNIGM 79
Cdd:TIGR01271 1218 MDVQGLtaKYTEAGRAVLQDLSFSVEGGQRVGLLGRTGSGKSTLLSALLRLLSTE-GEIQIDGVswNSVTLQTWRKAFGV 1296

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796    80 VFQAYALFPNmTVAQNVSFGLRVSGKsrsEIDATVKE--MLSLI-----RLDHLADRYPYQMSGGQQQRVALARALATKP 152
Cdd:TIGR01271 1297 IPQKVFIFSG-TFRKNLDPYEQWSDE---EIWKVAEEvgLKSVIeqfpdKLDFVLVDGGYVLSNGHKQLMCLARSILSKA 1372

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 559158796   153 QVLLLDEPLSALDAkirISLREEIRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGS 217
Cdd:TIGR01271 1373 KILLLDEPSAHLDP---VTLQIIRKTLKQSFSNCTVILSEHRVEALLECQQFLVIEGSSVKQYDS 1434
PLN03130 PLN03130
ABC transporter C family member; Provisional
 18-218 1.74e-10

ABC transporter C family member; Provisional


Pssm-ID: 215595 [Multi-domain]  Cd Length: 1622  Bit Score: 62.45  E-value: 1.74e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   18 VVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDV--VNLRPNQRNIGMVFQAYALFpnmtvAQN 95
Cdd:PLN03130 1254 VLHGLSFEISPSEKVGIVGRTGAGKSSMLNALFRIVELERGRILIDGCDIskFGLMDLRKVLGIIPQAPVLF-----SGT 1328

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   96 VSFGLRVSGKSRseiDATVKEMLSLIRLDHLADRYPYQM-----------SGGQQQRVALARALATKPQVLLLDEPLSAL 164
Cdd:PLN03130 1329 VRFNLDPFNEHN---DADLWESLERAHLKDVIRRNSLGLdaevseagenfSVGQRQLLSLARALLRRSKILVLDEATAAV 1405

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 559158796  165 ----DAKIRISLREEIRAiqqklgITTVFVTHDQEEALSiSDRIVVMHEGRADQIGSP 218
Cdd:PLN03130 1406 dvrtDALIQKTIREEFKS------CTMLIIAHRLNTIID-CDRILVLDAGRVVEFDTP 1456
ABCC_CFTR2 cd03289
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ...
 4-217 3.59e-10

ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.


Pssm-ID: 213256 [Multi-domain]  Cd Length: 275  Bit Score: 59.87  E-value: 3.59e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSF--GTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDnGSIEIDGK--DVVNLRPNQRNIGM 79
Cdd:cd03289    3 MTVKDLTAKYteGGNAVLENISFSISPGQRVGLLGRTGSGKSTLLSAFLRLLNTE-GDIQIDGVswNSVPLQKWRKAFGV 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  80 VFQAYALFPNmTVAQNvsfgLRVSGKSRSEIDATVKEMLSLI--------RLDHLADRYPYQMSGGQQQRVALARALATK 151
Cdd:cd03289   82 IPQKVFIFSG-TFRKN----LDPYGKWSDEEIWKVAEEVGLKsvieqfpgQLDFVLVDGGCVLSHGHKQLMCLARSVLSK 156

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 559158796 152 PQVLLLDEPLSALDAKIRISLReeiRAIQQKLGITTVFVTHDQEEALSISDRIVVMHEGRADQIGS 217
Cdd:cd03289  157 AKILLLDEPSAHLDPITYQVIR---KTLKQAFADCTVILSEHRIEAMLECQRFLVIEENKVRQYDS 219
3a01205 TIGR00956
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
 29-167 5.70e-10

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273362 [Multi-domain]  Cd Length: 1394  Bit Score: 60.89  E-value: 5.70e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796    29 GEFVSFLGPSGCGKTTVLRMIAGFETpdNGSIEiDGKDVVNLRPN----QRNIGMVFQAYALFPNMTVAQNVSFG--LRV 102
Cdd:TIGR00956  789 GTLTALMGASGAGKTTLLNVLAERVT--TGVIT-GGDRLVNGRPLdssfQRSIGYVQQQDLHLPTSTVRESLRFSayLRQ 865

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 559158796   103 SGK-SRSEIDATVKEMLSLIRLDHLADRYPYQMSGG----QQQRVALARALATKPQVLL-LDEPLSALDAK 167
Cdd:TIGR00956  866 PKSvSKSEKMEYVEEVIKLLEMESYADAVVGVPGEGlnveQRKRLTIGVELVAKPKLLLfLDEPTSGLDSQ 936
PTZ00243 PTZ00243
ABC transporter; Provisional
 26-257 3.57e-09

ABC transporter; Provisional


Pssm-ID: 240327 [Multi-domain]  Cd Length: 1560  Bit Score: 58.25  E-value: 3.57e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   26 VGKGEFVSFLGPSGCGKTTVL----RMIagfETPdNGSIEIDGKDV--VNLRPNQRNIGMVFQAYALFpNMTVAQNVS-- 97
Cdd:PTZ00243 1333 IAPREKVGIVGRTGSGKSTLLltfmRMV---EVC-GGEIRVNGREIgaYGLRELRRQFSMIPQDPVLF-DGTVRQNVDpf 1407

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   98 --------------FGLRVSGKSRSE-IDATVKEMLSlirldhladrypyQMSGGQQQRVALARALATKPQ-VLLLDEPL 161
Cdd:PTZ00243 1408 leassaevwaalelVGLRERVASESEgIDSRVLEGGS-------------NYSVGQRQLMCMARALLKKGSgFILMDEAT 1474

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  162 S----ALDAKIRISLREEIRAIqqklgitTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNRPASRFvasfvgtL 237
Cdd:PTZ00243 1475 AnidpALDRQIQATVMSAFSAY-------TVITIAHRLHTVAQYDKIIVMDHGAVAEMGSPRELVMNRQSIF-------H 1540

                         250       260
                  ....*....|....*....|
gi 559158796  238 NMLEASVSEPAQNSIDLDGR 257
Cdd:PTZ00243 1541 SMVEALGRSEAKRFLQLVGR 1560
MRP_assoc_pro TIGR00957
multi drug resistance-associated protein (MRP); This model describes multi drug ...
 14-221 3.65e-09

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]


Pssm-ID: 188098 [Multi-domain]  Cd Length: 1522  Bit Score: 58.42  E-value: 3.65e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796    14 GTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDV--VNLRPNQRNIGMVFQAYALFPNmT 91
Cdd:TIGR00957 1297 DLDLVLRHINVTIHGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGLNIakIGLHDLRFKITIIPQDPVLFSG-S 1375

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796    92 VAQNVS-FGlrvsgkSRSEID-------ATVKEMLSLI--RLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPL 161
Cdd:TIGR00957 1376 LRMNLDpFS------QYSDEEvwwalelAHLKTFVSALpdKLDHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEAT 1449

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   162 SALDAKIRISLREEIRAiqQKLGITTVFVTHDQEEALSISdRIVVMHEGRADQIGSPFDI 221
Cdd:TIGR00957 1450 AAVDLETDNLIQSTIRT--QFEDCTVLTIAHRLNTIMDYT-RVIVLDKGEVAEFGAPSNL 1506
PRK10938 PRK10938
putative molybdenum transport ATP-binding protein ModF; Provisional
 6-197 4.18e-09

putative molybdenum transport ATP-binding protein ModF; Provisional


Pssm-ID: 182852 [Multi-domain]  Cd Length: 490  Bit Score: 57.72  E-value: 4.18e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   6 IKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGfETPDNGSIEI--------DGKDVVNLRpnqRNI 77
Cdd:PRK10938 263 LNNGVVSYNDRPILHNLSWQVNPGEHWQIVGPNGAGKSTLLSLITG-DHPQGYSNDLtlfgrrrgSGETIWDIK---KHI 338

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  78 GMVFQAYAL-FPNMTVAQNV-------SFGL--RVSGKSRSEIDatvkEMLSLIRLD-HLADRYPYQMSGGQQQRVALAR 146
Cdd:PRK10938 339 GYVSSSLHLdYRVSTSVRNVilsgffdSIGIyqAVSDRQQKLAQ----QWLDILGIDkRTADAPFHSLSWGQQRLALIVR 414

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 559158796 147 ALATKPQVLLLDEPLSALDAKIRISLReeiRAIQQKLG---ITTVFVTHDQEEA 197
Cdd:PRK10938 415 ALVKHPTLLILDEPLQGLDPLNRQLVR---RFVDVLISegeTQLLFVSHHAEDA 465
PRK10938 PRK10938
putative molybdenum transport ATP-binding protein ModF; Provisional
 1-190 9.08e-09

putative molybdenum transport ATP-binding protein ModF; Provisional


Pssm-ID: 182852 [Multi-domain]  Cd Length: 490  Bit Score: 56.56  E-value: 9.08e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   1 MAFLNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNL--RPNQRNIG 78
Cdd:PRK10938   1 MSSLQISQGTFRLSDTKTLQLPSLTLNAGDSWAFVGANGSGKSALARALAGELPLLSGERQSQFSHITRLsfEQLQKLVS 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  79 MVFQAyalfpNMTvaQNVSFGLRVSGKSRSEI------DATVKEMLS-LIRLDHLADRYPYQMSGGQQQRVALARALATK 151
Cdd:PRK10938  81 DEWQR-----NNT--DMLSPGEDDTGRTTAEIiqdevkDPARCEQLAqQFGITALLDRRFKYLSTGETRKTLLCQALMSE 153

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 559158796 152 PQVLLLDEPLSALDAKIRISLREEIRAIQQKlGITTVFV 190
Cdd:PRK10938 154 PDLLILDEPFDGLDVASRQQLAELLASLHQS-GITLVLV 191
PLN03073 PLN03073
ABC transporter F family; Provisional
 32-224 4.04e-08

ABC transporter F family; Provisional


Pssm-ID: 215558 [Multi-domain]  Cd Length: 718  Bit Score: 54.87  E-value: 4.04e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  32 VSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGKDVVNLRPNQRNIGMVFQAYALFPNMTVAQNV----------SFGlr 101
Cdd:PLN03073 538 IAMVGPNGIGKSTILKLISGELQPSSGTVFRSAKVRMAVFSQHHVDGLDLSSNPLLYMMRCFPGVpeqklrahlgSFG-- 615

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 102 VSGksrseidatvkemlslirldHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSALDAkirislrEEIRAIQQ 181
Cdd:PLN03073 616 VTG--------------------NLALQPMYTLSGGQKSRVAFAKITFKKPHILLLDEPSNHLDL-------DAVEALIQ 668

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 559158796 182 KLGI---TTVFVTHDQEEALSISDRIVVMHEGRADQIGSPFDIYNR 224
Cdd:PLN03073 669 GLVLfqgGVLMVSHDEHLISGSVDELWVVSEGKVTPFHGTFHDYKK 714
PRK13546 PRK13546
teichoic acids export ABC transporter ATP-binding subunit TagH;
21-216 8.47e-08

teichoic acids export ABC transporter ATP-binding subunit TagH;


Pssm-ID: 184131 [Multi-domain]  Cd Length: 264  Bit Score: 52.90  E-value: 8.47e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  21 DFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGkdvvnlrpnqrNIGMVFQAYALFPNMTVAQNVSFGL 100
Cdd:PRK13546  42 DISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTVGKVDRNG-----------EVSVIAISAGLSGQLTGIENIEFKM 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 101 RVSGKSRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSALDAKIRISLREEIRAIQ 180
Cdd:PRK13546 111 LCMGFKRKEIKAMTPKIIEFSELGEFIYQPVKKYSSGMRAKLGFSINITVNPDILVIDEALSVGDQTFAQKCLDKIYEFK 190

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 559158796 181 QKlGITTVFVTHDQEEALSISDRIVVMHEGRADQIG 216
Cdd:PRK13546 191 EQ-NKTIFFVSHNLGQVRQFCTKIAWIEGGKLKDYG 225
tagH PRK13545
teichoic acids export protein ATP-binding subunit; Provisional
 26-216 1.80e-07

teichoic acids export protein ATP-binding subunit; Provisional


Pssm-ID: 184130 [Multi-domain]  Cd Length: 549  Bit Score: 52.59  E-value: 1.80e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  26 VGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIDGkdvvnlrpnqrNIGMVFQAYALFPNMTVAQNVSFGLRVSGK 105
Cdd:PRK13545  47 VPEGEIVGIIGLNGSGKSTLSNLIAGVTMPNKGTVDIKG-----------SAALIAISSGLNGQLTGIENIELKGLMMGL 115

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 106 SRSEIDATVKEMLSLIRLDHLADRYPYQMSGGQQQRVALARALATKPQVLLLDEPLSALDAKIRISLREEIRAIQQKlGI 185
Cdd:PRK13545 116 TKEKIKEIIPEIIEFADIGKFIYQPVKTYSSGMKSRLGFAISVHINPDILVIDEALSVGDQTFTKKCLDKMNEFKEQ-GK 194

                        170       180       190
                 ....*....|....*....|....*....|.
gi 559158796 186 TTVFVTHDQEEALSISDRIVVMHEGRADQIG 216
Cdd:PRK13545 195 TIFFISHSLSQVKSFCTKALWLHYGQVKEYG 225
PRK10636 PRK10636
putative ABC transporter ATP-binding protein; Provisional
 4-220 3.74e-07

putative ABC transporter ATP-binding protein; Provisional


Pssm-ID: 236729 [Multi-domain]  Cd Length: 638  Bit Score: 51.71  E-value: 3.74e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTNTVVHDFNLAVGKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEIdGKDVV----------NLRPN 73
Cdd:PRK10636 313 LKMEKVSAGYGDRIILDSIKLNLVPGSRIGLLGRNGAGKSTLIKLLAGELAPVSGEIGL-AKGIKlgyfaqhqleFLRAD 391

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  74 QRNIGMVFQayaLFPNMTVAQNVSF--GLRVSGKSRSEIDAtvkemlslirldhladrypyQMSGGQQQRVALARALATK 151
Cdd:PRK10636 392 ESPLQHLAR---LAPQELEQKLRDYlgGFGFQGDKVTEETR--------------------RFSGGEKARLVLALIVWQR 448

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 559158796 152 PQVLLLDEPLSALDAKIRISLREEIRAIQQKLgittVFVTHDQEEALSISDRIVVMHEGRADqigsPFD 220
Cdd:PRK10636 449 PNLLLLDEPTNHLDLDMRQALTEALIDFEGAL----VVVSHDRHLLRSTTDDLYLVHDGKVE----PFD 509
PLN03140 PLN03140
ABC transporter G family member; Provisional
 29-167 1.04e-06

ABC transporter G family member; Provisional


Pssm-ID: 215599 [Multi-domain]  Cd Length: 1470  Bit Score: 50.61  E-value: 1.04e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   29 GEFVSFLGPSGCGKTTVLRMIAGFETpdNGSIEIDGKdVVNLRPNQ----RNIGMVFQAYALFPNMTVAQNVSFG--LRV 102
Cdd:PLN03140  906 GVLTALMGVSGAGKTTLMDVLAGRKT--GGYIEGDIR-ISGFPKKQetfaRISGYCEQNDIHSPQVTVRESLIYSafLRL 982

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 559158796  103 SGK-SRSEIDATVKEMLSLIRLDHLADR---YP--YQMSGGQQQRVALARALATKPQVLLLDEPLSALDAK 167
Cdd:PLN03140  983 PKEvSKEEKMMFVDEVMELVELDNLKDAivgLPgvTGLSTEQRKRLTIAVELVANPSIIFMDEPTSGLDAR 1053
ABC_UvrA cd03238
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in ...
 99-207 3.79e-06

ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.


Pssm-ID: 213205 [Multi-domain]  Cd Length: 176  Bit Score: 46.55  E-value: 3.79e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  99 GLRVSGKSRSEIDATVKEMLSLIRLDHLA------------DRYPYQMSGGQQQRVALARALA--TKPQVLLLDEPLSAL 164
Cdd:cd03238   41 GLYASGKARLISFLPKFSRNKLIFIDQLQflidvglgyltlGQKLSTLSGGELQRVKLASELFsePPGTLFILDEPSTGL 120

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 559158796 165 DAKIRISLREEIRAIQQkLGITTVFVTHDqEEALSISDRIVVM 207
Cdd:cd03238  121 HQQDINQLLEVIKGLID-LGNTVILIEHN-LDVLSSADWIIDF 161
ABC_UvrA_I cd03270
ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair ...
 21-207 5.15e-06

ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.


Pssm-ID: 213237 [Multi-domain]  Cd Length: 226  Bit Score: 46.87  E-value: 5.15e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  21 DFNLAVGKGEFVSFLGPSGCGKTTVL---------------------RMIAGFETPDNGSIE-------IDGKdvvNLRP 72
Cdd:cd03270   13 NVDVDIPRNKLVVITGVSGSGKSSLAfdtiyaegqrryveslsayarQFLGQMDKPDVDSIEglspaiaIDQK---TTSR 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  73 NQRN-IGMVFQAYA----LFPNMTVAQNVSFGLRVSgksrseidatvkemlslirLDHLA-DRYPYQMSGGQQQRVALAR 146
Cdd:cd03270   90 NPRStVGTVTEIYDylrlLFARVGIRERLGFLVDVG-------------------LGYLTlSRSAPTLSGGEAQRIRLAT 150

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 559158796 147 ALATKPQVLL--LDEPLSALDAKIRISLREEIRAIQQkLGITTVFVTHDqEEALSISDRIVVM 207
Cdd:cd03270  151 QIGSGLTGVLyvLDEPSIGLHPRDNDRLIETLKRLRD-LGNTVLVVEHD-EDTIRAADHVIDI 211
ABC_Rad50 cd03240
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ...
 133-195 5.57e-06

ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.


Pssm-ID: 213207 [Multi-domain]  Cd Length: 204  Bit Score: 46.45  E-value: 5.57e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 133 QMSGGQQQ------RVALARALATKPQVLLLDEPLSALDA-KIRISLREEIRAIQQKLGITTVFVTHDQE 195
Cdd:cd03240  115 RCSGGEKVlasliiRLALAETFGSNCGILALDEPTTNLDEeNIEESLAEIIEERKSQKNFQLIVITHDEE 184
uvra TIGR00630
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ...
 87-227 3.72e-05

excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273184 [Multi-domain]  Cd Length: 925  Bit Score: 45.77  E-value: 3.72e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   87 FPNMTVAQNVSF--GLRVSGKSRSEIDATVKEMLSLIR------LDHLA-DRYPYQMSGGQQQRVALARALATK-PQVL- 155
Cdd:TIGR00630 433 VSELSIREAHEFfnQLTLTPEEKKIAEEVLKEIRERLGflidvgLDYLSlSRAAGTLSGGEAQRIRLATQIGSGlTGVLy 512

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 559158796  156 LLDEPLSALDAKIRISLREEIRAIqQKLGITTVFVTHDqEEALSISDRIVVM------HEGRADQIGSPFDIYNRPAS 227
Cdd:TIGR00630 513 VLDEPSIGLHQRDNRRLINTLKRL-RDLGNTLIVVEHD-EDTIRAADYVIDIgpgageHGGEVVASGTPEEILANPDS 588
PLN03073 PLN03073
ABC transporter F family; Provisional
 133-224 7.88e-05

ABC transporter F family; Provisional


Pssm-ID: 215558 [Multi-domain]  Cd Length: 718  Bit Score: 44.47  E-value: 7.88e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 133 QMSGGQQQRVALARALATKPQVLLLDEPLSALDAKIRISLREEIraiqQKLGITTVFVTHDQEEALSISDRIVVMHEGRA 212
Cdd:PLN03073 344 TFSGGWRMRIALARALFIEPDLLLLDEPTNHLDLHAVLWLETYL----LKWPKTFIVVSHAREFLNTVVTDILHLHGQKL 419

                         90
                 ....*....|..
gi 559158796 213 DQIGSPFDIYNR 224
Cdd:PLN03073 420 VTYKGDYDTFER 431
ABC_Class2 cd03227
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ...
 133-207 2.05e-04

ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.


Pssm-ID: 213194 [Multi-domain]  Cd Length: 162  Bit Score: 41.19  E-value: 2.05e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 559158796 133 QMSGGQQQRVALARALA---TKP-QVLLLDEPLSALDAKIRISLREEIRAIQQKlGITTVFVTHDQEEALsISDRIVVM 207
Cdd:cd03227   77 QLSGGEKELSALALILAlasLKPrPLYILDEIDRGLDPRDGQALAEAILEHLVK-GAQVIVITHLPELAE-LADKLIHI 153
ABCC_SUR2 cd03288
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The ...
 4-236 2.75e-04

ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The sulfonylurea receptor SUR is an ATP binding cassette (ABC) protein of the ABCC/MRP family. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.


Pssm-ID: 213255 [Multi-domain]  Cd Length: 257  Bit Score: 41.82  E-value: 2.75e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   4 LNIKNLKKSFGTN--TVVHDFNLAVGKGEFVSFLGPSGCGKTTV----LRMIAGFEtpdnGSIEIDGKDV--VNLRPNQR 75
Cdd:cd03288   20 IKIHDLCVRYENNlkPVLKHVKAYIKPGQKVGICGRTGSGKSSLslafFRMVDIFD----GKIVIDGIDIskLPLHTLRS 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  76 NIGMVFQAYALFpnmtvAQNVSFGLRVSGKSrseIDATVKEMLSLIRLDHLADRYP-----------YQMSGGQQQRVAL 144
Cdd:cd03288   96 RLSIILQDPILF-----SGSIRFNLDPECKC---TDDRLWEALEIAQLKNMVKSLPggldavvteggENFSVGQRQLFCL 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796 145 ARALATKPQVLLLDEPLSALD-AKIRISLREEIRAIQQKlgiTTVFVTHDQEEALSiSDRIVVMHEGRADQIGSPFDIYN 223
Cdd:cd03288  168 ARAFVRKSSILIMDEATASIDmATENILQKVVMTAFADR---TVVTIAHRVSTILD-ADLVLVLSRGILVECDTPENLLA 243

                        250
                 ....*....|...
gi 559158796 224 RPASRFvASFVGT 236
Cdd:cd03288  244 QEDGVF-ASLVRT 255
PRK15064 PRK15064
ABC transporter ATP-binding protein; Provisional
 23-165 7.56e-04

ABC transporter ATP-binding protein; Provisional


Pssm-ID: 237894 [Multi-domain]  Cd Length: 530  Bit Score: 41.42  E-value: 7.56e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  23 NLAV--GKGEFVSFLGPSGCGKTTVLRMIAGFETPDNGSIEID-GKDVVNLRPNQ------RNIGMVFQA---------- 83
Cdd:PRK15064  19 NISVkfGGGNRYGLIGANGCGKSTFMKILGGDLEPSAGNVSLDpNERLGKLRQDQfafeefTVLDTVIMGhtelwevkqe 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796  84 ----YALfPNMTVAQnvsfGLRVSgksrsEIDATVKEM-----------LsLIRLDHLADRYPYQMSG---GQQQRVALA 145
Cdd:PRK15064  99 rdriYAL-PEMSEED----GMKVA-----DLEVKFAEMdgytaearageL-LLGVGIPEEQHYGLMSEvapGWKLRVLLA 167

                        170       180
                 ....*....|....*....|
gi 559158796 146 RALATKPQVLLLDEPLSALD 165
Cdd:PRK15064 168 QALFSNPDILLLDEPTNNLD 187
PRK10636 PRK10636
putative ABC transporter ATP-binding protein; Provisional
 135-205 1.86e-03

putative ABC transporter ATP-binding protein; Provisional


Pssm-ID: 236729 [Multi-domain]  Cd Length: 638  Bit Score: 40.15  E-value: 1.86e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 559158796 135 SGGQQQRVALARALATKPQVLLLDEPLSALDAKIRISLREEIRAIQQklgiTTVFVTHDQEEALSISDRIV 205
Cdd:PRK10636 151 SGGWRMRLNLAQALICRSDLLLLDEPTNHLDLDAVIWLEKWLKSYQG----TLILISHDRDFLDPIVDKII 217
PRK00635 PRK00635
excinuclease ABC subunit A; Provisional
 82-205 1.99e-03

excinuclease ABC subunit A; Provisional


Pssm-ID: 234806 [Multi-domain]  Cd Length: 1809  Bit Score: 40.20  E-value: 1.99e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 559158796   82 QAYALFPNMTVAQNVSFGLRVSGKSRS--EIDATVKEMLS-LIRL--DHLA-DRYPYQMSGGQQQRVALARALATKPQ-- 153
Cdd:PRK00635  419 KTFAEFQQMSLQELFIFLSQLPSKSLSieEVLQGLKSRLSiLIDLglPYLTpERALATLSGGEQERTALAKHLGAELIgi 498

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 559158796  154 VLLLDEPLSALDAKIRISLREEIRAIQQKlGITTVFVTHDqEEALSISDRIV 205
Cdd:PRK00635  499 TYILDEPSIGLHPQDTHKLINVIKKLRDQ-GNTVLLVEHD-EQMISLADRII 548
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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