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Conserved domains on  [gi|643028431|gb|AIA90820|]
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transpeptidase, partial [uncultured Marinomonas sp.]

Protein Classification

penicillin-binding protein 2( domain architecture ID 1000616)

penicillin-binding protein (PBP) 2 is a membrane-associated enzyme that is involved in the synthesis of cross-linked peptidoglycan

Gene Ontology:  GO:0008658|GO:0016020|GO:0009252
PubMed:  32762868|32442851

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
FtsI super family cl34037
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell ...
3-168 3.08e-69

Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell cycle control, cell division, chromosome partitioning, Cell wall/membrane/envelope biogenesis];


The actual alignment was detected with superfamily member COG0768:

Pssm-ID: 440531 [Multi-domain]  Cd Length: 568  Bit Score: 219.31  E-value: 3.08e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 643028431   3 KIWRNILVEDSYEPGSTMKIFTVAAAINSGNFNANATFK-SGSFQIDGKNVYDWDRSGWGYITYQDAFIRSSNVGMAHLE 81
Cdd:COG0768  281 EPLRNRAVQGTYEPGSTFKPFTAAAALEEGVITPDTTFDcPGYYRVGGRTIRDWDRGGHGTLTLTEALAKSSNVGFYKLA 360
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 643028431  82 QQMGAKTWLSYIHKFGFLKKTGSKMPNEVAGSI---EYKYPIEQANTAFGQAINVTALQMMQGFSAIANHGTMVKPYLVK 158
Cdd:COG0768  361 LRLGIDKLYDYLKKFGLGQKTGIDLPGEASGLLpspKRWYPGETATMSIGQGLSVTPLQLAQAYAAIANGGVLVKPHLVK 440
                        170
                 ....*....|
gi 643028431 159 KVVDPNNQKV 168
Cdd:COG0768  441 EIVDPDGEVV 450
 
Name Accession Description Interval E-value
FtsI COG0768
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell ...
3-168 3.08e-69

Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell cycle control, cell division, chromosome partitioning, Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440531 [Multi-domain]  Cd Length: 568  Bit Score: 219.31  E-value: 3.08e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 643028431   3 KIWRNILVEDSYEPGSTMKIFTVAAAINSGNFNANATFK-SGSFQIDGKNVYDWDRSGWGYITYQDAFIRSSNVGMAHLE 81
Cdd:COG0768  281 EPLRNRAVQGTYEPGSTFKPFTAAAALEEGVITPDTTFDcPGYYRVGGRTIRDWDRGGHGTLTLTEALAKSSNVGFYKLA 360
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 643028431  82 QQMGAKTWLSYIHKFGFLKKTGSKMPNEVAGSI---EYKYPIEQANTAFGQAINVTALQMMQGFSAIANHGTMVKPYLVK 158
Cdd:COG0768  361 LRLGIDKLYDYLKKFGLGQKTGIDLPGEASGLLpspKRWYPGETATMSIGQGLSVTPLQLAQAYAAIANGGVLVKPHLVK 440
                        170
                 ....*....|
gi 643028431 159 KVVDPNNQKV 168
Cdd:COG0768  441 EIVDPDGEVV 450
strep_PBP2X NF038271
penicillin-binding protein PBP2X;
5-166 3.01e-52

penicillin-binding protein PBP2X;


Pssm-ID: 468442 [Multi-domain]  Cd Length: 748  Bit Score: 177.13  E-value: 3.01e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 643028431   5 WRNILVEDSYEPGSTMKIFTVAAAINSGNFNANATFKSGS-FQIDGKNVYDWD----RSGWGYITYQDAFIRSSNVGMAH 79
Cdd:NF038271 322 WNNLLYQTNYEPGSTMKVMTLASAIDNGTFNPNETYSNSNgLTIADATINDWDvnegLSTGQYMTYAQGFAYSSNVGMTL 401
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 643028431  80 LEQQMGAKTWLSYIHKFGFLKKTGSKMPNEVAGSIEYKYPIEQANTAFGQAINVTALQMMQGFSAIANHGTMVKPYLVKK 159
Cdd:NF038271 402 LEQKMGDDKWLNYLSKFKFGLPTRFGMGDESSGILPSDNIVTIAMSSFGQGISVTQVQMLRAFSAISNDGVMLEPKFISA 481

                 ....*..
gi 643028431 160 VVDPNNQ 166
Cdd:NF038271 482 IYDPNTG 488
Transpeptidase pfam00905
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss: ...
5-169 1.41e-45

Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss:P14677) is conserved in all members of this family.


Pssm-ID: 425939 [Multi-domain]  Cd Length: 296  Bit Score: 151.03  E-value: 1.41e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 643028431    5 WRNILVEDSYEPGSTMKIFTVAAAINSGNFNANATFKSGSFQIDGKNVY-DWDRSGWGYITYQDAFIRSSNVGMAHLEQQ 83
Cdd:pfam00905  31 LRNRAVTSRYEPGSTFKPFTALAALDNGVLKPDETIFDWPGKQQGGKSIgDWNQDQVGIGTLRQALEYSSNWYMQKLAQK 110
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 643028431   84 MGAKTWLSYIHKFGFLKKTGSKMPNEVAGsIEYKYPIEQANTAFGQAINVTALQMMQGFSAIANHGTMVKPYLVKKVVDP 163
Cdd:pfam00905 111 LGADKLRSYLKKFGYGNKTGIGLPGENAG-YLTPYWLEGATASFGIGLTITPLQQAQAYAAIANGGKLVPPHLVKSIEDK 189

                  ....*.
gi 643028431  164 NNQKVI 169
Cdd:pfam00905 190 VDPKVL 195
pbp2_mrdA TIGR03423
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 ...
14-168 3.56e-33

penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 (PBP-2), a protein whose gene (designated pbpA or mrdA) generally is found next to the gene for RodA, a protein required for rod (bacillus) shape in many bacteria. PBP-2 acts as a transpeptidase for cell elongation (hence, rod-shape). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]


Pssm-ID: 274573 [Multi-domain]  Cd Length: 592  Bit Score: 123.40  E-value: 3.56e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 643028431   14 YEPGSTMKIFTVAAAINSGNFNANAT-FKSGSFQIDGKNVYDWDRSGWGYITYQDAFIRSSNVGMAHLEQQMGAKTWLSY 92
Cdd:TIGR03423 304 YPPGSTFKPVVALAALEEGVITPETRiYCPGYFQLGGRRFRCWKRGGHGRVDLRKAIEESCDVYFYQLALRLGIDKIAEY 383
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 643028431   93 IHKFGFLKKTGSKMPNEVAG---SIEYK--------YPIEQANTAFGQ-AINVTALQMMQGFSAIANHGTMVKPYLVKKV 160
Cdd:TIGR03423 384 AKRFGFGQKTGIDLPGEKSGlvpSREWKrkrfgqpwYPGDTLNVSIGQgYVLVTPLQLAVATAALANGGKLYKPHLVKSI 463

                  ....*...
gi 643028431  161 VDPNNQKV 168
Cdd:TIGR03423 464 EDPDGGVV 471
PRK15105 PRK15105
peptidoglycan synthase FtsI; Provisional
6-163 3.77e-15

peptidoglycan synthase FtsI; Provisional


Pssm-ID: 185060 [Multi-domain]  Cd Length: 578  Bit Score: 72.16  E-value: 3.77e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 643028431   6 RNILVEDSYEPGSTMKIFTVAAAINSGNFNANATFKSGSFQIDGKNVYDWDRsgWGYITYQDAFIRSSNVGMAHLEQQMG 85
Cdd:PRK15105 294 RNRAITDVFEPGSTVKPMVVMTALQRGVVKENSVLNTVPYRINGHEIKDVAR--YSELTLTGVLQKSSNVGVSKLALAMP 371
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 643028431  86 AKTWLSYIHKFGFLKKTGSKMPNEVAGSIEYKY---PIEQANTAFGQAINVTALQMMQGFSAIANHGtMVKPYLVKKvVD 162
Cdd:PRK15105 372 SSALVDTYSRFGLGKATNLGLVGERSGLYPQKQrwsDIERATFSFGYGLMVTPLQLARVYATIGSYG-IYRPLSITK-VD 449

                 .
gi 643028431 163 P 163
Cdd:PRK15105 450 P 450
 
Name Accession Description Interval E-value
FtsI COG0768
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell ...
3-168 3.08e-69

Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell cycle control, cell division, chromosome partitioning, Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440531 [Multi-domain]  Cd Length: 568  Bit Score: 219.31  E-value: 3.08e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 643028431   3 KIWRNILVEDSYEPGSTMKIFTVAAAINSGNFNANATFK-SGSFQIDGKNVYDWDRSGWGYITYQDAFIRSSNVGMAHLE 81
Cdd:COG0768  281 EPLRNRAVQGTYEPGSTFKPFTAAAALEEGVITPDTTFDcPGYYRVGGRTIRDWDRGGHGTLTLTEALAKSSNVGFYKLA 360
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 643028431  82 QQMGAKTWLSYIHKFGFLKKTGSKMPNEVAGSI---EYKYPIEQANTAFGQAINVTALQMMQGFSAIANHGTMVKPYLVK 158
Cdd:COG0768  361 LRLGIDKLYDYLKKFGLGQKTGIDLPGEASGLLpspKRWYPGETATMSIGQGLSVTPLQLAQAYAAIANGGVLVKPHLVK 440
                        170
                 ....*....|
gi 643028431 159 KVVDPNNQKV 168
Cdd:COG0768  441 EIVDPDGEVV 450
strep_PBP2X NF038271
penicillin-binding protein PBP2X;
5-166 3.01e-52

penicillin-binding protein PBP2X;


Pssm-ID: 468442 [Multi-domain]  Cd Length: 748  Bit Score: 177.13  E-value: 3.01e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 643028431   5 WRNILVEDSYEPGSTMKIFTVAAAINSGNFNANATFKSGS-FQIDGKNVYDWD----RSGWGYITYQDAFIRSSNVGMAH 79
Cdd:NF038271 322 WNNLLYQTNYEPGSTMKVMTLASAIDNGTFNPNETYSNSNgLTIADATINDWDvnegLSTGQYMTYAQGFAYSSNVGMTL 401
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 643028431  80 LEQQMGAKTWLSYIHKFGFLKKTGSKMPNEVAGSIEYKYPIEQANTAFGQAINVTALQMMQGFSAIANHGTMVKPYLVKK 159
Cdd:NF038271 402 LEQKMGDDKWLNYLSKFKFGLPTRFGMGDESSGILPSDNIVTIAMSSFGQGISVTQVQMLRAFSAISNDGVMLEPKFISA 481

                 ....*..
gi 643028431 160 VVDPNNQ 166
Cdd:NF038271 482 IYDPNTG 488
Transpeptidase pfam00905
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss: ...
5-169 1.41e-45

Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss:P14677) is conserved in all members of this family.


Pssm-ID: 425939 [Multi-domain]  Cd Length: 296  Bit Score: 151.03  E-value: 1.41e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 643028431    5 WRNILVEDSYEPGSTMKIFTVAAAINSGNFNANATFKSGSFQIDGKNVY-DWDRSGWGYITYQDAFIRSSNVGMAHLEQQ 83
Cdd:pfam00905  31 LRNRAVTSRYEPGSTFKPFTALAALDNGVLKPDETIFDWPGKQQGGKSIgDWNQDQVGIGTLRQALEYSSNWYMQKLAQK 110
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 643028431   84 MGAKTWLSYIHKFGFLKKTGSKMPNEVAGsIEYKYPIEQANTAFGQAINVTALQMMQGFSAIANHGTMVKPYLVKKVVDP 163
Cdd:pfam00905 111 LGADKLRSYLKKFGYGNKTGIGLPGENAG-YLTPYWLEGATASFGIGLTITPLQQAQAYAAIANGGKLVPPHLVKSIEDK 189

                  ....*.
gi 643028431  164 NNQKVI 169
Cdd:pfam00905 190 VDPKVL 195
pbp2_mrdA TIGR03423
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 ...
14-168 3.56e-33

penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 (PBP-2), a protein whose gene (designated pbpA or mrdA) generally is found next to the gene for RodA, a protein required for rod (bacillus) shape in many bacteria. PBP-2 acts as a transpeptidase for cell elongation (hence, rod-shape). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]


Pssm-ID: 274573 [Multi-domain]  Cd Length: 592  Bit Score: 123.40  E-value: 3.56e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 643028431   14 YEPGSTMKIFTVAAAINSGNFNANAT-FKSGSFQIDGKNVYDWDRSGWGYITYQDAFIRSSNVGMAHLEQQMGAKTWLSY 92
Cdd:TIGR03423 304 YPPGSTFKPVVALAALEEGVITPETRiYCPGYFQLGGRRFRCWKRGGHGRVDLRKAIEESCDVYFYQLALRLGIDKIAEY 383
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 643028431   93 IHKFGFLKKTGSKMPNEVAG---SIEYK--------YPIEQANTAFGQ-AINVTALQMMQGFSAIANHGTMVKPYLVKKV 160
Cdd:TIGR03423 384 AKRFGFGQKTGIDLPGEKSGlvpSREWKrkrfgqpwYPGDTLNVSIGQgYVLVTPLQLAVATAALANGGKLYKPHLVKSI 463

                  ....*...
gi 643028431  161 VDPNNQKV 168
Cdd:TIGR03423 464 EDPDGGVV 471
MrcB COG0744
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall ...
16-168 3.84e-23

Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440507 [Multi-domain]  Cd Length: 630  Bit Score: 94.99  E-value: 3.84e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 643028431  16 PGSTMKIFTVAAAINSGnFNANATFKSGSFQIDGKN--VYDWDRSGWGYITYQDAFIRSSNVGMAHLEQQMGAKTWLSYI 93
Cdd:COG0744  363 PGSTFKPFVYAAALEQG-YTPATTVDDEPVTFPGGGwsPKNYDGRYRGPVTLREALANSLNTPAVRLAQEVGLDKVVDTA 441
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 643028431  94 HKFGFlkktgsKMPNEVAGSIeykypieqantAFGqAINVTALQMMQGFSAIANHGTMVKPYLVKKVVDPNNQKV 168
Cdd:COG0744  442 RRLGI------TSPLDPNPSL-----------ALG-TSEVSPLEMASAYATFANGGVYVEPHAITKVTDADGKVL 498
MrcA COG5009
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis];
16-171 7.06e-18

Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 444033 [Multi-domain]  Cd Length: 785  Bit Score: 79.82  E-value: 7.06e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 643028431  16 PGSTMKIFTVAAAINSGnFNANATFKSGSFQID---GKNVY---DWDRSGWGYITYQDAFIRSSNVGMAHLEQQMGAKTW 89
Cdd:COG5009  459 PGSSFKPFVYAAALDNG-YTPATIINDAPIVFDdggGGGVWrpkNYSGKFYGPTTLREALEKSRNLVTVRLLQDVGIDYV 537
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 643028431  90 LSYIHKFGFlkktGSKMPNEVA---GSIEykypieqantafgqainVTALQMMQGFSAIANHGTMVKPYLVKKVVDPNNq 166
Cdd:COG5009  538 IDYAERFGI----YSKLPPNLSlalGSGE-----------------VTPLEMARAYAVFANGGYRVEPYLIDRIEDRNG- 595

                 ....*
gi 643028431 167 KVIIR 171
Cdd:COG5009  596 KVIYR 600
PRK15105 PRK15105
peptidoglycan synthase FtsI; Provisional
6-163 3.77e-15

peptidoglycan synthase FtsI; Provisional


Pssm-ID: 185060 [Multi-domain]  Cd Length: 578  Bit Score: 72.16  E-value: 3.77e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 643028431   6 RNILVEDSYEPGSTMKIFTVAAAINSGNFNANATFKSGSFQIDGKNVYDWDRsgWGYITYQDAFIRSSNVGMAHLEQQMG 85
Cdd:PRK15105 294 RNRAITDVFEPGSTVKPMVVMTALQRGVVKENSVLNTVPYRINGHEIKDVAR--YSELTLTGVLQKSSNVGVSKLALAMP 371
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 643028431  86 AKTWLSYIHKFGFLKKTGSKMPNEVAGSIEYKY---PIEQANTAFGQAINVTALQMMQGFSAIANHGtMVKPYLVKKvVD 162
Cdd:PRK15105 372 SSALVDTYSRFGLGKATNLGLVGERSGLYPQKQrwsDIERATFSFGYGLMVTPLQLARVYATIGSYG-IYRPLSITK-VD 449

                 .
gi 643028431 163 P 163
Cdd:PRK15105 450 P 450
PRK10795 PRK10795
penicillin-binding protein 2; Provisional
14-168 2.32e-10

penicillin-binding protein 2; Provisional


Pssm-ID: 236761 [Multi-domain]  Cd Length: 634  Bit Score: 58.24  E-value: 2.32e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 643028431  14 YEPGSTMKIFTVAAAINSGNFNANAT-FKSGSFQIDG--KNVYDWDRSGWGYITYQDAFIRSSNVGMAHLEQQMGAKTWL 90
Cdd:PRK10795 327 YPPASTVKPYVAVSALSAGVITRNTSlFDPGWWQLPGseKRYRDWKKWGHGRLNVTKSLEESADTFFYQVAYDMGIDRLS 406
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 643028431  91 SYIHKFGFLKKTGSKMPNEVAGSI--------EYKYPIEQANT---AFGQAI-NVTALQMMQGFSAIANHGTMVKPYLVK 158
Cdd:PRK10795 407 EWMGKFGYGHYTGIDLAEERSGNMptrewkqkRFKKPWYQGDTipvGIGQGYwTATPIQMSKALMTLINDGIVKVPHLLM 486
                        170
                 ....*....|
gi 643028431 159 KVVDpNNQKV 168
Cdd:PRK10795 487 STAE-DGKQV 495
mrcA PRK11636
penicillin-binding protein 1a; Provisional
71-168 5.45e-05

penicillin-binding protein 1a; Provisional


Pssm-ID: 183248 [Multi-domain]  Cd Length: 850  Bit Score: 42.43  E-value: 5.45e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 643028431  71 RSSNVGMAHLEQQMGAKTWLSYIHKFGFlkktgskmPNEVAGSIEykypieqaNTAFGQAiNVTALQMMQGFSAIANHGT 150
Cdd:PRK11636 523 QSKNVVMVRAMRAMGVDYAAEYLQRFGF--------PAQNIVHTE--------SLALGSA-SFTPMQVARGYAVMANGGF 585
                         90
                 ....*....|....*...
gi 643028431 151 MVKPYLVKKVVDPNNQKV 168
Cdd:PRK11636 586 LVDPYFISKIENDQGGVI 603
PRK14850 PRK14850
penicillin-binding protein 1b; Provisional
17-166 2.53e-03

penicillin-binding protein 1b; Provisional


Pssm-ID: 237835 [Multi-domain]  Cd Length: 764  Bit Score: 37.52  E-value: 2.53e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 643028431  17 GSTMKIFTVAAAINSGN-FNANATFKSGSFQIDGKNVYDW-----DRSGWGYITYQDAFIRSSNVGMAHLEQQMGAKTWL 90
Cdd:PRK14850 453 GSLSKPITYLTALSQPEkYHLNTWISDTPISIKLDNGQYWtpknnNFSFSGKVMLIDALIHSINIPTVHLSINLGLKKLV 532
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 643028431  91 SYIHKFGFLKKTGSKMPNEVAGsieykypieqantafgqAINVTALQMMQGFSAIANHGTMVKPYLVKKVVDPNNQ 166
Cdd:PRK14850 533 DSWILLGISSNYITPLPSISLG-----------------AINLTPMEVAQVFQIIGSGGYKSSLSSIRSIISDDNK 591
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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