|
Name |
Accession |
Description |
Interval |
E-value |
| PRK15121 |
PRK15121 |
MDR efflux pump AcrAB transcriptional activator RobA; |
1-289 |
0e+00 |
|
MDR efflux pump AcrAB transcriptional activator RobA;
Pssm-ID: 185076 [Multi-domain] Cd Length: 289 Bit Score: 649.76 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 732686030 1 MDQAGIIRDLLIWLEGHLDQPLSLDNVAAKAGYSKWHLQRMFKDVTGHAIGAYIRARRLSKSAVALRLTARPILDIALQY 80
Cdd:PRK15121 1 MDQAGIIRDLLIWLEGHLDQPLSLDNVAAKAGYSKWHLQRMFKDVTGHAIGAYIRARRLSKAAVALRLTSRPILDIALQY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 732686030 81 RFDSQQTFTRAFKKQFAQTPALYRRSPEWSAFGIRPPLRLGEFTMPEHKFVTLEDTPLIGVTQSYSCSLEQISDFRHEMR 160
Cdd:PRK15121 81 RFDSQQTFTRAFKKQFAQTPALYRRSPEWSAFGIRPPIRLGEFTLPEHEFVTLPETPLVGVTQSYSCSLEQISDFRHEMR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 732686030 161 YQFWHDFLGNAPTIPPVLYGLNETRPSQDKDDEQEVFYTTALAQDQADGYVLTGHPVMLQGGEYVMFTYEGLGTGVQEFI 240
Cdd:PRK15121 161 VQFWRDFLGNAPTIPPVLYGLHETRPSQEKDDEQEVFYTTALEPDQADGYVQTGHPVMLQGGEYVMFTYEGLGTGLQEFI 240
|
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 732686030 241 LTVYGTCMPMLNLTRRKGQDIERYYPAEDAKAGDRPINLRCELLIPIRR 289
Cdd:PRK15121 241 LTVYGTCMPMLNLTRRKGQDIERYYPAEDAKAGDRPINLRCEYLIPIRR 289
|
|
| RobA_TF |
NF012228 |
MDR efflux pump AcrAB transcriptional activator RobA; The original characterization of RobA as ... |
3-288 |
0e+00 |
|
MDR efflux pump AcrAB transcriptional activator RobA; The original characterization of RobA as a Right side Origin of replication Binding protein A (robA) may be misleading. Characterizations in large numbers of papers since then treat RobA as a transcriptional activator of the AcrAB antibiotic efflux pump.
Pssm-ID: 467958 [Multi-domain] Cd Length: 286 Bit Score: 621.54 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 732686030 3 QAGIIRDLLIWLEGHLDQPLSLDNVAAKAGYSKWHLQRMFKDVTGHAIGAYIRARRLSKSAVALRLTARPILDIALQYRF 82
Cdd:NF012228 1 QAGIIRDLLVWLEGHLDQPLSLDNVAAKAGYSKWHLQRMFKDVTGQAIGAYIRARRLSKAAVALRLTSRPILDIALQYRF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 732686030 83 DSQQTFTRAFKKQFAQTPALYRRSPEWSAFGIRPPLRLGEFTMPEHKFVTLEDTPLIGVTQSYSCSLEQISDFRHEMRYQ 162
Cdd:NF012228 81 DSQQTFTRAFKKQFNQTPALYRRSEDWNAFGICPPIRLGKFTLPEPEFVTLPEQHLVGITQSYSCTLEQISDFRTEMRVQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 732686030 163 FWHDFLGNAPTIPPVLYGLNETRPSQDKDDEQEVFYTTALAQDQADGYVLTGHPVMLQGGEYVMFTYEGLGTGVQEFILT 242
Cdd:NF012228 161 FWRQYLGNTPTIPPVLYGLHHSRPSKEKDDEQEVLYTTALEPEHAPEGVQEGQPVVLEGGEYVQFTYEGPPEGLQDFILT 240
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 732686030 243 VYGTCMPMLNLTRRKGQDIERYYPAEDAKAGDRPINLRCELLIPIR 288
Cdd:NF012228 241 VYGTCMPTLNLTRRKGQDIERFYPHGDKKRDEPPTHIRCEYLIPIR 286
|
|
| HTH_ARAC |
smart00342 |
helix_turn_helix, arabinose operon control protein; |
21-104 |
3.31e-29 |
|
helix_turn_helix, arabinose operon control protein;
Pssm-ID: 197666 [Multi-domain] Cd Length: 84 Bit Score: 106.48 E-value: 3.31e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 732686030 21 PLSLDNVAAKAGYSKWHLQRMFKDVTGHAIGAYIRARRLSKSAVALRLTARPILDIALQYRFDSQQTFTRAFKKQFAQTP 100
Cdd:smart00342 1 PLTLEDLAEALGVSPRHLQRLFKKETGTTPKQYLRDRRLERARRLLRDTDLSVTEIALRVGFSSQSYFSRAFKKLFGVTP 80
|
....
gi 732686030 101 ALYR 104
Cdd:smart00342 81 SEYR 84
|
|
| YdeE |
COG3708 |
Predicted transcriptional regulator YdeE, contains AraC-type DNA-binding domain [Transcription] ... |
126-288 |
9.44e-27 |
|
Predicted transcriptional regulator YdeE, contains AraC-type DNA-binding domain [Transcription];
Pssm-ID: 442922 Cd Length: 157 Bit Score: 102.41 E-value: 9.44e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 732686030 126 PEHKFVTLEDTPLIGVTQSYSCSLEQisdfRHEMRYQFWHDFLGNAP-TIP-----PVLYGLNetrpSQDKDDEQEVFYT 199
Cdd:COG3708 1 MEYRIVEKPAFKLVGLSARTSNSDEE----ANEEIPALWQRFLPEGLaEIPnlsnpGGLYGVC----TDYESDEGEFDYL 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 732686030 200 TALAQDQADGYVLTGHPVMLQGGEYVMFTYEG-LGTGVQEFILTVYGTCMPMLNLTRRKGQDIERYYPAEDAKAgdrpiN 278
Cdd:COG3708 73 AGVEVSSFDEVPEGLETLEIPAGTYAVFTHKGpMPEALQETWQYIYSEWLPSSGYERADGPDFEVYDERDDPSP-----D 147
|
170
....*....|
gi 732686030 279 LRCELLIPIR 288
Cdd:COG3708 148 SEVEIWIPIK 157
|
|
| GyrI-like |
pfam06445 |
GyrI-like small molecule binding domain; This family contains the small molecule binding ... |
127-287 |
6.19e-26 |
|
GyrI-like small molecule binding domain; This family contains the small molecule binding domain of a number of different bacterial transcription activators. This family also contains DNA gyrase inhibitors. The GyrI superfamily contains a diad of the SHS2 module, adapted for small-molecule binding. The GyrI superfamily includes a family of secreted forms that is found only in animals and the bacterial pathogen Leptospira.
Pssm-ID: 428947 Cd Length: 153 Bit Score: 100.18 E-value: 6.19e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 732686030 127 EHKFVTLEDTPLIGVTQSYSCSLEQISDFRHEMRYQFWHDFLGNAPtipPVLYGLNETRPsqDKDDEQEVFYTTALAQDQ 206
Cdd:pfam06445 1 EVEIVELPAFRVAGLRHRGPYNEEGIGALWEELCAWASENGLSPAP---SPLIGVSYDDP--EVTEDEELRYDAGVAVPI 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 732686030 207 ADGYVLTGHPVMLQGGEYVMFTYEGLGTGVQEFILTVYGTCMPMLNLTRRKGQDIERYYPAEDAkagDRPINLRCELLIP 286
Cdd:pfam06445 76 PVEGPEGVEELELPGGEYAVFRHKGPYDDLQETYAKIYGEWLPESGYERRDGPSFEIYLNDPRE---VPEEELKTEIYIP 152
|
.
gi 732686030 287 I 287
Cdd:pfam06445 153 V 153
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK15121 |
PRK15121 |
MDR efflux pump AcrAB transcriptional activator RobA; |
1-289 |
0e+00 |
|
MDR efflux pump AcrAB transcriptional activator RobA;
Pssm-ID: 185076 [Multi-domain] Cd Length: 289 Bit Score: 649.76 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 732686030 1 MDQAGIIRDLLIWLEGHLDQPLSLDNVAAKAGYSKWHLQRMFKDVTGHAIGAYIRARRLSKSAVALRLTARPILDIALQY 80
Cdd:PRK15121 1 MDQAGIIRDLLIWLEGHLDQPLSLDNVAAKAGYSKWHLQRMFKDVTGHAIGAYIRARRLSKAAVALRLTSRPILDIALQY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 732686030 81 RFDSQQTFTRAFKKQFAQTPALYRRSPEWSAFGIRPPLRLGEFTMPEHKFVTLEDTPLIGVTQSYSCSLEQISDFRHEMR 160
Cdd:PRK15121 81 RFDSQQTFTRAFKKQFAQTPALYRRSPEWSAFGIRPPIRLGEFTLPEHEFVTLPETPLVGVTQSYSCSLEQISDFRHEMR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 732686030 161 YQFWHDFLGNAPTIPPVLYGLNETRPSQDKDDEQEVFYTTALAQDQADGYVLTGHPVMLQGGEYVMFTYEGLGTGVQEFI 240
Cdd:PRK15121 161 VQFWRDFLGNAPTIPPVLYGLHETRPSQEKDDEQEVFYTTALEPDQADGYVQTGHPVMLQGGEYVMFTYEGLGTGLQEFI 240
|
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 732686030 241 LTVYGTCMPMLNLTRRKGQDIERYYPAEDAKAGDRPINLRCELLIPIRR 289
Cdd:PRK15121 241 LTVYGTCMPMLNLTRRKGQDIERYYPAEDAKAGDRPINLRCEYLIPIRR 289
|
|
| RobA_TF |
NF012228 |
MDR efflux pump AcrAB transcriptional activator RobA; The original characterization of RobA as ... |
3-288 |
0e+00 |
|
MDR efflux pump AcrAB transcriptional activator RobA; The original characterization of RobA as a Right side Origin of replication Binding protein A (robA) may be misleading. Characterizations in large numbers of papers since then treat RobA as a transcriptional activator of the AcrAB antibiotic efflux pump.
Pssm-ID: 467958 [Multi-domain] Cd Length: 286 Bit Score: 621.54 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 732686030 3 QAGIIRDLLIWLEGHLDQPLSLDNVAAKAGYSKWHLQRMFKDVTGHAIGAYIRARRLSKSAVALRLTARPILDIALQYRF 82
Cdd:NF012228 1 QAGIIRDLLVWLEGHLDQPLSLDNVAAKAGYSKWHLQRMFKDVTGQAIGAYIRARRLSKAAVALRLTSRPILDIALQYRF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 732686030 83 DSQQTFTRAFKKQFAQTPALYRRSPEWSAFGIRPPLRLGEFTMPEHKFVTLEDTPLIGVTQSYSCSLEQISDFRHEMRYQ 162
Cdd:NF012228 81 DSQQTFTRAFKKQFNQTPALYRRSEDWNAFGICPPIRLGKFTLPEPEFVTLPEQHLVGITQSYSCTLEQISDFRTEMRVQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 732686030 163 FWHDFLGNAPTIPPVLYGLNETRPSQDKDDEQEVFYTTALAQDQADGYVLTGHPVMLQGGEYVMFTYEGLGTGVQEFILT 242
Cdd:NF012228 161 FWRQYLGNTPTIPPVLYGLHHSRPSKEKDDEQEVLYTTALEPEHAPEGVQEGQPVVLEGGEYVQFTYEGPPEGLQDFILT 240
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 732686030 243 VYGTCMPMLNLTRRKGQDIERYYPAEDAKAGDRPINLRCELLIPIR 288
Cdd:NF012228 241 VYGTCMPTLNLTRRKGQDIERFYPHGDKKRDEPPTHIRCEYLIPIR 286
|
|
| PRK10219 |
PRK10219 |
superoxide response transcriptional regulator SoxS; |
1-106 |
5.79e-45 |
|
superoxide response transcriptional regulator SoxS;
Pssm-ID: 182314 [Multi-domain] Cd Length: 107 Bit Score: 147.76 E-value: 5.79e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 732686030 1 MDQAGIIRDLLIWLEGHLDQPLSLDNVAAKAGYSKWHLQRMFKDVTGHAIGAYIRARRLSKSAVALRLTARPILDIALQY 80
Cdd:PRK10219 1 MSHQKIIQTLIAWIDEHIDQPLNIDVVAKKSGYSKWYLQRMFRTVTHQTLGDYIRQRRLLLAAVELRTTERPIFDIAMDL 80
|
90 100
....*....|....*....|....*.
gi 732686030 81 RFDSQQTFTRAFKKQFAQTPALYRRS 106
Cdd:PRK10219 81 GYVSQQTFSRVFRRQFDRTPSDYRHR 106
|
|
| PRK11511 |
PRK11511 |
MDR efflux pump AcrAB transcriptional activator MarA; |
7-104 |
3.84e-33 |
|
MDR efflux pump AcrAB transcriptional activator MarA;
Pssm-ID: 236920 [Multi-domain] Cd Length: 127 Bit Score: 117.90 E-value: 3.84e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 732686030 7 IRDLLIWLEGHLDQPLSLDNVAAKAGYSKWHLQRMFKDVTGHAIGAYIRARRLSKSAVALRLTARPILDIALQYRFDSQQ 86
Cdd:PRK11511 11 IHSILDWIEDNLESPLSLEKVSERSGYSKWHLQRMFKKETGHSLGQYIRSRKMTEIAQKLKESNEPILYLAERYGFESQQ 90
|
90
....*....|....*...
gi 732686030 87 TFTRAFKKQFAQTPALYR 104
Cdd:PRK11511 91 TLTRTFKNYFDVPPHKYR 108
|
|
| HTH_ARAC |
smart00342 |
helix_turn_helix, arabinose operon control protein; |
21-104 |
3.31e-29 |
|
helix_turn_helix, arabinose operon control protein;
Pssm-ID: 197666 [Multi-domain] Cd Length: 84 Bit Score: 106.48 E-value: 3.31e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 732686030 21 PLSLDNVAAKAGYSKWHLQRMFKDVTGHAIGAYIRARRLSKSAVALRLTARPILDIALQYRFDSQQTFTRAFKKQFAQTP 100
Cdd:smart00342 1 PLTLEDLAEALGVSPRHLQRLFKKETGTTPKQYLRDRRLERARRLLRDTDLSVTEIALRVGFSSQSYFSRAFKKLFGVTP 80
|
....
gi 732686030 101 ALYR 104
Cdd:smart00342 81 SEYR 84
|
|
| YdeE |
COG3708 |
Predicted transcriptional regulator YdeE, contains AraC-type DNA-binding domain [Transcription] ... |
126-288 |
9.44e-27 |
|
Predicted transcriptional regulator YdeE, contains AraC-type DNA-binding domain [Transcription];
Pssm-ID: 442922 Cd Length: 157 Bit Score: 102.41 E-value: 9.44e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 732686030 126 PEHKFVTLEDTPLIGVTQSYSCSLEQisdfRHEMRYQFWHDFLGNAP-TIP-----PVLYGLNetrpSQDKDDEQEVFYT 199
Cdd:COG3708 1 MEYRIVEKPAFKLVGLSARTSNSDEE----ANEEIPALWQRFLPEGLaEIPnlsnpGGLYGVC----TDYESDEGEFDYL 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 732686030 200 TALAQDQADGYVLTGHPVMLQGGEYVMFTYEG-LGTGVQEFILTVYGTCMPMLNLTRRKGQDIERYYPAEDAKAgdrpiN 278
Cdd:COG3708 73 AGVEVSSFDEVPEGLETLEIPAGTYAVFTHKGpMPEALQETWQYIYSEWLPSSGYERADGPDFEVYDERDDPSP-----D 147
|
170
....*....|
gi 732686030 279 LRCELLIPIR 288
Cdd:COG3708 148 SEVEIWIPIK 157
|
|
| GyrI-like |
pfam06445 |
GyrI-like small molecule binding domain; This family contains the small molecule binding ... |
127-287 |
6.19e-26 |
|
GyrI-like small molecule binding domain; This family contains the small molecule binding domain of a number of different bacterial transcription activators. This family also contains DNA gyrase inhibitors. The GyrI superfamily contains a diad of the SHS2 module, adapted for small-molecule binding. The GyrI superfamily includes a family of secreted forms that is found only in animals and the bacterial pathogen Leptospira.
Pssm-ID: 428947 Cd Length: 153 Bit Score: 100.18 E-value: 6.19e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 732686030 127 EHKFVTLEDTPLIGVTQSYSCSLEQISDFRHEMRYQFWHDFLGNAPtipPVLYGLNETRPsqDKDDEQEVFYTTALAQDQ 206
Cdd:pfam06445 1 EVEIVELPAFRVAGLRHRGPYNEEGIGALWEELCAWASENGLSPAP---SPLIGVSYDDP--EVTEDEELRYDAGVAVPI 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 732686030 207 ADGYVLTGHPVMLQGGEYVMFTYEGLGTGVQEFILTVYGTCMPMLNLTRRKGQDIERYYPAEDAkagDRPINLRCELLIP 286
Cdd:pfam06445 76 PVEGPEGVEELELPGGEYAVFRHKGPYDDLQETYAKIYGEWLPESGYERRDGPSFEIYLNDPRE---VPEEELKTEIYIP 152
|
.
gi 732686030 287 I 287
Cdd:pfam06445 153 V 153
|
|
| GlxA |
COG4977 |
Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH ... |
7-105 |
7.09e-23 |
|
Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH domain [Transcription];
Pssm-ID: 444002 [Multi-domain] Cd Length: 318 Bit Score: 95.61 E-value: 7.09e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 732686030 7 IRDLLIWLEGHLDQPLSLDNVAAKAGYSKWHLQRMFKDVTGHAIGAYIRARRLSKSAVALRLTARPILDIALQYRFDSQQ 86
Cdd:COG4977 212 LARAQAWMEANLEEPLSVDELARRAGMSPRTLERRFRAATGTTPARYLQRLRLERARRLLETTDLSIEEIAAACGFGSAS 291
|
90
....*....|....*....
gi 732686030 87 TFTRAFKKQFAQTPALYRR 105
Cdd:COG4977 292 HFRRAFRRRFGVSPSAYRR 310
|
|
| AraC |
COG2207 |
AraC-type DNA-binding domain and AraC-containing proteins [Transcription]; |
8-106 |
8.11e-23 |
|
AraC-type DNA-binding domain and AraC-containing proteins [Transcription];
Pssm-ID: 441809 [Multi-domain] Cd Length: 258 Bit Score: 94.85 E-value: 8.11e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 732686030 8 RDLLIWLEGHLDQPLSLDNVAAKAGYSKWHLQRMFKDVTGHAIGAYIRARRLSKSAVALRLTARPILDIALQYRFDSQQT 87
Cdd:COG2207 155 LLLLLLLLLLLLLLLTLEELARELGLSPRTLSRLFKEETGTSPKQYLRELRLERAKRLLAETDLSISEIAYELGFSSQSH 234
|
90
....*....|....*....
gi 732686030 88 FTRAFKKQFAQTPALYRRS 106
Cdd:COG2207 235 FSRAFKKRFGVTPSEYRKR 253
|
|
| AraC_E_bind |
smart00871 |
Bacterial transcription activator, effector binding domain; This domain is found in the ... |
127-288 |
4.96e-21 |
|
Bacterial transcription activator, effector binding domain; This domain is found in the probable effector binding domain of a number of different bacterial transcription activators.and is also present in some DNA gyrase inhibitors. The absence of a HTH motif in the DNA gyrase inhibitors is thought to indicate the fact that these do not bind DNA.
Pssm-ID: 214874 [Multi-domain] Cd Length: 158 Bit Score: 87.15 E-value: 4.96e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 732686030 127 EHKFVTLEDTPLIGVTQSYSCSLEQISDFrhEMRYQFWHDFLGNAPTIPP-VLYGLNETRPSQDKDDEQEVFYTTALAQD 205
Cdd:smart00871 1 EVRIVELPAFKVAGLRHRGPNEDEKIPEL--WQRLIQWAKELGLLPVGNSgEPYGVYYDDPDDTPDGEFRYDAGVEVSDE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 732686030 206 QADGYVLtgHPVMLQGGEYVMFTYEGL-GTGVQEFILTVYGTCMPMLNLTRRKGQDIERYYPAEDakAGDRPINLRCELL 284
Cdd:smart00871 79 VEAPEGV--ETKTIPAGKYAVFTHKGGsYDEIQEAWEAIYGEWLPNSGYELRDAGPDFEVYLNDP--PDTDPEELVTEIY 154
|
....
gi 732686030 285 IPIR 288
Cdd:smart00871 155 IPVK 158
|
|
| HTH_18 |
pfam12833 |
Helix-turn-helix domain; |
27-106 |
1.88e-19 |
|
Helix-turn-helix domain;
Pssm-ID: 432818 [Multi-domain] Cd Length: 81 Bit Score: 80.71 E-value: 1.88e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 732686030 27 VAAKAGYSKWHLQRMFKDVTGHAIGAYIRARRLSKSAVAL-RLTARPILDIALQYRFDSQQTFTRAFKKQFAQTPALYRR 105
Cdd:pfam12833 1 LAAALGMSPRTLSRLFKRELGLSPKEYLRRLRLERARRLLlEDTGLSVAEIALALGFSDASHFSRAFRRLFGLTPSEYRR 80
|
.
gi 732686030 106 S 106
Cdd:pfam12833 81 R 81
|
|
| AdaA |
COG2169 |
Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), ... |
3-105 |
1.62e-15 |
|
Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), contains Zn-binding and two AraC-type DNA-binding domains [Replication, recombination and repair];
Pssm-ID: 441772 [Multi-domain] Cd Length: 358 Bit Score: 75.48 E-value: 1.62e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 732686030 3 QAGIIRDLLIWLEGHLDQPLSLDNVAAKAGYSKWHLQRMFKDVTGHAIGAYIRARRLSKSAVALRlTARPILDIALQYRF 82
Cdd:COG2169 82 RADLVARACRLIEAGAEDRPSLEDLAARLGLSPRHLRRLFKAHTGVTPKAYARARRLLRARQLLQ-TGLSVTDAAYAAGF 160
|
90 100
....*....|....*....|...
gi 732686030 83 DSQQTFTRAFKKQFAQTPALYRR 105
Cdd:COG2169 161 GSLSRFYEAFKKLLGMTPSAYRR 183
|
|
| ftrA |
PRK09393 |
transcriptional activator FtrA; Provisional |
10-106 |
1.70e-14 |
|
transcriptional activator FtrA; Provisional
Pssm-ID: 181818 [Multi-domain] Cd Length: 322 Bit Score: 72.30 E-value: 1.70e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 732686030 10 LLIWLEGHLDQPLSLDNVAAKAGYSKWHLQRMFKDVTGHAIGAYIRARRLSKSAVALRLTARPILDIALQYRFDSQQTFT 89
Cdd:PRK09393 223 LIDWMRAHLAEPHTVASLAARAAMSPRTFLRRFEAATGMTPAEWLLRERLARARDLLESSALSIDQIAERAGFGSEESLR 302
|
90
....*....|....*..
gi 732686030 90 RAFKKQFAQTPALYRRS 106
Cdd:PRK09393 303 HHFRRRAATSPAAYRKR 319
|
|
| PRK09685 |
PRK09685 |
DNA-binding transcriptional activator FeaR; Provisional |
17-106 |
2.11e-13 |
|
DNA-binding transcriptional activator FeaR; Provisional
Pssm-ID: 236612 [Multi-domain] Cd Length: 302 Bit Score: 68.90 E-value: 2.11e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 732686030 17 HLDQP-LSLDNVAAKAGYSKWHLQRMFKDvTGHAIGAYIRARRLSKSAVALR--LTARPILDIALQYRFDSQQTFTRAFK 93
Cdd:PRK09685 209 SIQEEiLRPEWIAGELGISVRSLYRLFAE-QGLVVAQYIRNRRLDRCADDLRpaADDEKITSIAYKWGFSDSSHFSTAFK 287
|
90
....*....|...
gi 732686030 94 KQFAQTPALYRRS 106
Cdd:PRK09685 288 QRFGVSPGEYRRK 300
|
|
| PRK10371 |
PRK10371 |
transcriptional regulator MelR; |
7-107 |
3.99e-09 |
|
transcriptional regulator MelR;
Pssm-ID: 182416 [Multi-domain] Cd Length: 302 Bit Score: 56.37 E-value: 3.99e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 732686030 7 IRDLLIWLEGHLDQPLSLDNVAAKAGYSKWHLQRMFKDVTGHAIGAYIRARRLSKSAVALRLTARPILDIALQYRFDSQQ 86
Cdd:PRK10371 193 VSQMLGFIAENYDQALTINDVAEHVKLNANYAMGIFQRVMQLTMKQYITAMRINHVRALLSDTDKSILDIALTAGFRSSS 272
|
90 100
....*....|....*....|.
gi 732686030 87 TFTRAFKKQFAQTPALYRRSP 107
Cdd:PRK10371 273 RFYSTFGKYVGMSPQQYRKLS 293
|
|
| PRK10572 |
PRK10572 |
arabinose operon transcriptional regulator AraC; |
7-108 |
1.02e-06 |
|
arabinose operon transcriptional regulator AraC;
Pssm-ID: 236717 [Multi-domain] Cd Length: 290 Bit Score: 49.20 E-value: 1.02e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 732686030 7 IRDLLIWLEGHLDQPLSLDNVAAKAGYSKWHLQRMFKDVTGHAIGAYIRARRLSKSAVALRLTARPILDIALQYRFDSQQ 86
Cdd:PRK10572 185 VREACQYISDHLASEFDIESVAQHVCLSPSRLAHLFRQQLGISVLRWREDQRISRAKLLLQTTRMPIATIGRNVGYDDQL 264
|
90 100
....*....|....*....|..
gi 732686030 87 TFTRAFKKQFAQTPALYRRSPE 108
Cdd:PRK10572 265 YFSRVFKKCTGASPSEFRARCE 286
|
|
| PRK13503 |
PRK13503 |
HTH-type transcriptional activator RhaS; |
2-100 |
1.50e-06 |
|
HTH-type transcriptional activator RhaS;
Pssm-ID: 184094 [Multi-domain] Cd Length: 278 Bit Score: 48.52 E-value: 1.50e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 732686030 2 DQAGIIRDLLIWLEGHLDQPLSLDNVAAKAGYSKWHLQRMFKDVTGHAIGAYIRARRLSKSAVALRLTARPILDIALQYR 81
Cdd:PRK13503 168 NSDARLNQLLAWLEDHFAEEVNWEALADQFSLSLRTLHRQLKQQTGLTPQRYLNRLRLLKARHLLRHSDASVTDIAYRCG 247
|
90
....*....|....*....
gi 732686030 82 FDSQQTFTRAFKKQFAQTP 100
Cdd:PRK13503 248 FGDSNHFSTLFRREFSWSP 266
|
|
| PRK13501 |
PRK13501 |
HTH-type transcriptional activator RhaR; |
9-105 |
1.88e-06 |
|
HTH-type transcriptional activator RhaR;
Pssm-ID: 184092 [Multi-domain] Cd Length: 290 Bit Score: 48.36 E-value: 1.88e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 732686030 9 DLLI-WLEGHLDQPLSLDNVAAKAGYSKWHLQRMFKDVTGHAIGAYIRARRLSKSAVALRLTARPILDIALQYRFDSQQT 87
Cdd:PRK13501 179 DLIMsALQQSLGAYFDMADFCHKNQLVERSLKQLFRQQTGMSISHYLRQIRLCHAKCLLRGSEHRISDIAARCGFEDSNY 258
|
90
....*....|....*...
gi 732686030 88 FTRAFKKQFAQTPALYRR 105
Cdd:PRK13501 259 FSAVFTREAGMTPRDYRQ 276
|
|
| Cass2 |
pfam14526 |
Integron-associated effector binding protein; This family contains Cass2 from Vibrio cholerae, ... |
131-287 |
3.52e-06 |
|
Integron-associated effector binding protein; This family contains Cass2 from Vibrio cholerae, an integron-associated protein that has been shown to bind cationic drug compounds with submicromolar affinity. Cass2 has been proposed to be representative of a larger family of independent effector-binding proteins associated with lateral gene transfer within Vibrio and other closely-related species.
Pssm-ID: 434016 [Multi-domain] Cd Length: 149 Bit Score: 45.81 E-value: 3.52e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 732686030 131 VTLEDTPLIGV----TQSYSCSLEQISDFRHEmryqFWHDFLGNAPTIPPVLYGLNETRPSQDKDDEQEVFYTTalaqdQ 206
Cdd:pfam14526 3 VELPSFTVAGIryegPNEYEDHNKEIGKFWEE----FNEDGRLPNIKKDDKSYGIYVDYEDEENEFDYYAGVEV-----P 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 732686030 207 ADGYVLTGHPVM-LQGGEYVMFTYEG-LGTGVQEFILTVYGTCMPMLNLTRRKGQDIERYYPAEDAkagdrpiNLRCELL 284
Cdd:pfam14526 74 SFSELPEGLVVIeIPGGKYAVFTIEGdFPDAIAEAWTRIYGWLLPNSGYERAGGPDFEVYKENGDE-------NMKIELY 146
|
...
gi 732686030 285 IPI 287
Cdd:pfam14526 147 IPV 149
|
|
| PRK13500 |
PRK13500 |
HTH-type transcriptional activator RhaR; |
6-104 |
1.74e-05 |
|
HTH-type transcriptional activator RhaR;
Pssm-ID: 184091 [Multi-domain] Cd Length: 312 Bit Score: 45.48 E-value: 1.74e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 732686030 6 IIRDLLIWLEGHLDQPLSLDNVAAKAGYSKWHLQRMFKDVTGHAIGAYIRARRLSKSAVALRLTARPILDIALQYRFDSQ 85
Cdd:PRK13500 207 LLDKLITRLAASLKSPFALDKFCDEASCSERVLRQQFRQQTGMTINQYLRQVRVCHAQYLLQHSRLLISDISTECGFEDS 286
|
90
....*....|....*....
gi 732686030 86 QTFTRAFKKQFAQTPALYR 104
Cdd:PRK13500 287 NYFSVVFTRETGMTPSQWR 305
|
|
| PRK15435 |
PRK15435 |
bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada; |
19-108 |
2.75e-05 |
|
bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada;
Pssm-ID: 185333 [Multi-domain] Cd Length: 353 Bit Score: 45.17 E-value: 2.75e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 732686030 19 DQPLSLDNVAAKAGYSKWHLQRMFKDVTGHAIGAYIRARRLSKSAVALRlTARPILDIALQYRFDSQQTFTRAFKKQFAQ 98
Cdd:PRK15435 97 ETPVTLEALADQVAMSPFHLHRLFKATTGMTPKAWQQAWRARRLREALA-KGESVTTSILNAGFPDSSSYYRKADETLGM 175
|
90
....*....|
gi 732686030 99 TPALYRRSPE 108
Cdd:PRK15435 176 TAKQFRHGGE 185
|
|
| PRK13502 |
PRK13502 |
HTH-type transcriptional activator RhaR; |
6-104 |
5.33e-05 |
|
HTH-type transcriptional activator RhaR;
Pssm-ID: 184093 [Multi-domain] Cd Length: 282 Bit Score: 43.89 E-value: 5.33e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 732686030 6 IIRDLLIWLEGHLDQPLSLDNVAAKAGYSKWHLQRMFKDVTGHAIGAYIRARRLSKSAVALRLTARPILDIALQYRFDSQ 85
Cdd:PRK13502 177 LLDKLITALANSLECPFALDAFCQQEQCSERVLRQQFRAQTGMTINQYLRQVRICHAQYLLQHSPLMISEISMQCGFEDS 256
|
90
....*....|....*....
gi 732686030 86 QTFTRAFKKQFAQTPALYR 104
Cdd:PRK13502 257 NYFSVVFTRETGMTPSQWR 275
|
|
| HTH_AraC |
pfam00165 |
Bacterial regulatory helix-turn-helix proteins, AraC family; In the absence of arabinose, the ... |
73-105 |
9.85e-05 |
|
Bacterial regulatory helix-turn-helix proteins, AraC family; In the absence of arabinose, the N-terminal arm of AraC binds to the DNA binding domain (pfam00165) and helps to hold the two DNA binding domains in a relative orientation that favours DNA looping. In the presence of arabinose, the arms bind over the arabinose on the dimerization domain, thus freeing the DNA-binding domains. The freed DNA-binding domains are then able to assume a conformation suitable for binding to the adjacent DNA sites that are utilized when AraC activates transcription, and hence AraC ceases looping the DNA when arabinose is added.
Pssm-ID: 425497 [Multi-domain] Cd Length: 42 Bit Score: 39.06 E-value: 9.85e-05
10 20 30
....*....|....*....|....*....|...
gi 732686030 73 ILDIALQYRFdSQQTFTRAFKKQFAQTPALYRR 105
Cdd:pfam00165 11 IADIADELGF-SRSYFSRLFKKYTGVTPSQYRH 42
|
|
| HTH_AraC |
pfam00165 |
Bacterial regulatory helix-turn-helix proteins, AraC family; In the absence of arabinose, the ... |
14-55 |
2.77e-04 |
|
Bacterial regulatory helix-turn-helix proteins, AraC family; In the absence of arabinose, the N-terminal arm of AraC binds to the DNA binding domain (pfam00165) and helps to hold the two DNA binding domains in a relative orientation that favours DNA looping. In the presence of arabinose, the arms bind over the arabinose on the dimerization domain, thus freeing the DNA-binding domains. The freed DNA-binding domains are then able to assume a conformation suitable for binding to the adjacent DNA sites that are utilized when AraC activates transcription, and hence AraC ceases looping the DNA when arabinose is added.
Pssm-ID: 425497 [Multi-domain] Cd Length: 42 Bit Score: 37.90 E-value: 2.77e-04
10 20 30 40
....*....|....*....|....*....|....*....|..
gi 732686030 14 LEGHLDQPLSLDNVAAKAGYSKWHLQRMFKDVTGHAIGAYIR 55
Cdd:pfam00165 1 LRENLSTNLTIADIADELGFSRSYFSRLFKKYTGVTPSQYRH 42
|
|
| |
