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Conserved domains on  [gi|760012251|gb|AJO96420|]
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Mak16p [Saccharomyces cerevisiae YJM1381]

Protein Classification

MAK16 family protein( domain architecture ID 11473955)

MAK16 family protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
MAK16 COG5129
Nuclear protein with HMG-like acidic region [General function prediction only];
1-306 1.60e-147

Nuclear protein with HMG-like acidic region [General function prediction only];


:

Pssm-ID: 227458 [Multi-domain]  Cd Length: 303  Bit Score: 416.37  E-value: 1.60e-147
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 760012251   1 MSDEIVWQVINQSFCSHRIKApNGQNFCRNEYNVTGLCTRQSCPLANSKYATVKCDNGKLYLYMKTPERAHTPAKLWERI 80
Cdd:COG5129    1 MSDESLWQVSGENFCSFRIKT-EEQNFCRNEYNVTGLCDRQSCPLANSRYATVRADNGKLYLYMKTPERAHVPRKLWERI 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 760012251  81 KLSKNYTKALQQIDEHLLHWSKFFRHKCKQRFTKLTQVMITERRLALREEERHYVGVAPKVKRREQNRERKALVAAKIEK 160
Cdd:COG5129   80 KLSKNYEKALKQIDESLLFWDEKVIHKCKQRLTKLTQYLLKARRLALFKEHGEYMVRKPKMNRREKLRERKALNAAKFEK 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 760012251 161 AIEKELMDRLKSGAYGDKPLNVDEKVWKKIMGQMeeENSQDEEEDWDEEEESDDGEVEYVADDGEGEYVDVDDLEKWLAD 240
Cdd:COG5129  160 NIEKELMLRLKSGIYGDTPLNVREHLWNKAATER--EKRQDEKERYVEEEEESDTELEAVTDDSEKEKTKKKDLEKWLGS 237
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 760012251 241 SDREASSASESESDSESESDSDSDEENKNSAKRRKKGTSAKTKRPKVEIEYEEEHEVQNAEQEVAQ 306
Cdd:COG5129  238 DQSMETSESEEEESSESESDEDEDEDNKGKIRKRKTDDAKKSRKPHIHIEYEQERENEKIPAVQHS 303
 
Name Accession Description Interval E-value
MAK16 COG5129
Nuclear protein with HMG-like acidic region [General function prediction only];
1-306 1.60e-147

Nuclear protein with HMG-like acidic region [General function prediction only];


Pssm-ID: 227458 [Multi-domain]  Cd Length: 303  Bit Score: 416.37  E-value: 1.60e-147
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 760012251   1 MSDEIVWQVINQSFCSHRIKApNGQNFCRNEYNVTGLCTRQSCPLANSKYATVKCDNGKLYLYMKTPERAHTPAKLWERI 80
Cdd:COG5129    1 MSDESLWQVSGENFCSFRIKT-EEQNFCRNEYNVTGLCDRQSCPLANSRYATVRADNGKLYLYMKTPERAHVPRKLWERI 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 760012251  81 KLSKNYTKALQQIDEHLLHWSKFFRHKCKQRFTKLTQVMITERRLALREEERHYVGVAPKVKRREQNRERKALVAAKIEK 160
Cdd:COG5129   80 KLSKNYEKALKQIDESLLFWDEKVIHKCKQRLTKLTQYLLKARRLALFKEHGEYMVRKPKMNRREKLRERKALNAAKFEK 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 760012251 161 AIEKELMDRLKSGAYGDKPLNVDEKVWKKIMGQMeeENSQDEEEDWDEEEESDDGEVEYVADDGEGEYVDVDDLEKWLAD 240
Cdd:COG5129  160 NIEKELMLRLKSGIYGDTPLNVREHLWNKAATER--EKRQDEKERYVEEEEESDTELEAVTDDSEKEKTKKKDLEKWLGS 237
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 760012251 241 SDREASSASESESDSESESDSDSDEENKNSAKRRKKGTSAKTKRPKVEIEYEEEHEVQNAEQEVAQ 306
Cdd:COG5129  238 DQSMETSESEEEESSESESDEDEDEDNKGKIRKRKTDDAKKSRKPHIHIEYEQERENEKIPAVQHS 303
PLN00040 PLN00040
Protein MAK16 homolog; Provisional
1-191 5.06e-84

Protein MAK16 homolog; Provisional


Pssm-ID: 215038 [Multi-domain]  Cd Length: 233  Bit Score: 252.77  E-value: 5.06e-84
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 760012251   1 MSDEIVWQVINQSFCSHRIKAPNGqNFCRNEYNVTGLCTRQSCPLANSKYATVKCDNGKLYLYMKTPERAHTPAKLWERI 80
Cdd:PLN00040   2 QHDEVIWQVINHNHCSFKAKIDTG-NFCRNKYNVTGLCNRSSCPLANSRYATIREEDGRFYLYMKTIERAHMPNKLWEKV 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 760012251  81 KLSKNYTKALQQIDEHLLHWSKFFRHKCKQRFTKLTQVMITERRLALREEERhYVGVAPKVKRREQNRERKALVAAKIEK 160
Cdd:PLN00040  81 KLSRNYEKALEQIDKHLAYWPKFLVHKNKQRLTKMTQYLIRMRKLALKTREK-IVTTPRKLLKRERRRESKAQKAAQLEK 159
                        170       180       190
                 ....*....|....*....|....*....|.
gi 760012251 161 AIEKELMDRLKSGAYGDKpLNVDEKVWKKIM 191
Cdd:PLN00040 160 SIEKELLERLKSGTYGDI-YNFPSKSYNKVL 189
Ribosomal_L28e pfam01778
Ribosomal L28e protein family;
5-118 1.04e-50

Ribosomal L28e protein family;


Pssm-ID: 460323  Cd Length: 115  Bit Score: 163.46  E-value: 1.04e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 760012251    5 IVWQVI--NQSFcSHRIKAPNGQNFCRNEYNVTGLCTRQSCPLANSKYATVKCDNGKLYLYMKTPERAHTPAKLWERIKL 82
Cdd:pfam01778   1 LIWEIIrnNNSF-LVKTRTGNGQTFSREPYNLTGLCSRKYCGLANSKYATVREDGGGVYLYTKKAERAHKPAKLWEKITL 79
                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 760012251   83 SKNYTKALQQIDEHLLHWSKFFRHKCKQRFTKLTQV 118
Cdd:pfam01778  80 SKNYRKALKQIDNHLKGYRPDLRHAAKQRASAILQS 115
 
Name Accession Description Interval E-value
MAK16 COG5129
Nuclear protein with HMG-like acidic region [General function prediction only];
1-306 1.60e-147

Nuclear protein with HMG-like acidic region [General function prediction only];


Pssm-ID: 227458 [Multi-domain]  Cd Length: 303  Bit Score: 416.37  E-value: 1.60e-147
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 760012251   1 MSDEIVWQVINQSFCSHRIKApNGQNFCRNEYNVTGLCTRQSCPLANSKYATVKCDNGKLYLYMKTPERAHTPAKLWERI 80
Cdd:COG5129    1 MSDESLWQVSGENFCSFRIKT-EEQNFCRNEYNVTGLCDRQSCPLANSRYATVRADNGKLYLYMKTPERAHVPRKLWERI 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 760012251  81 KLSKNYTKALQQIDEHLLHWSKFFRHKCKQRFTKLTQVMITERRLALREEERHYVGVAPKVKRREQNRERKALVAAKIEK 160
Cdd:COG5129   80 KLSKNYEKALKQIDESLLFWDEKVIHKCKQRLTKLTQYLLKARRLALFKEHGEYMVRKPKMNRREKLRERKALNAAKFEK 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 760012251 161 AIEKELMDRLKSGAYGDKPLNVDEKVWKKIMGQMeeENSQDEEEDWDEEEESDDGEVEYVADDGEGEYVDVDDLEKWLAD 240
Cdd:COG5129  160 NIEKELMLRLKSGIYGDTPLNVREHLWNKAATER--EKRQDEKERYVEEEEESDTELEAVTDDSEKEKTKKKDLEKWLGS 237
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 760012251 241 SDREASSASESESDSESESDSDSDEENKNSAKRRKKGTSAKTKRPKVEIEYEEEHEVQNAEQEVAQ 306
Cdd:COG5129  238 DQSMETSESEEEESSESESDEDEDEDNKGKIRKRKTDDAKKSRKPHIHIEYEQERENEKIPAVQHS 303
PLN00040 PLN00040
Protein MAK16 homolog; Provisional
1-191 5.06e-84

Protein MAK16 homolog; Provisional


Pssm-ID: 215038 [Multi-domain]  Cd Length: 233  Bit Score: 252.77  E-value: 5.06e-84
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 760012251   1 MSDEIVWQVINQSFCSHRIKAPNGqNFCRNEYNVTGLCTRQSCPLANSKYATVKCDNGKLYLYMKTPERAHTPAKLWERI 80
Cdd:PLN00040   2 QHDEVIWQVINHNHCSFKAKIDTG-NFCRNKYNVTGLCNRSSCPLANSRYATIREEDGRFYLYMKTIERAHMPNKLWEKV 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 760012251  81 KLSKNYTKALQQIDEHLLHWSKFFRHKCKQRFTKLTQVMITERRLALREEERhYVGVAPKVKRREQNRERKALVAAKIEK 160
Cdd:PLN00040  81 KLSRNYEKALEQIDKHLAYWPKFLVHKNKQRLTKMTQYLIRMRKLALKTREK-IVTTPRKLLKRERRRESKAQKAAQLEK 159
                        170       180       190
                 ....*....|....*....|....*....|.
gi 760012251 161 AIEKELMDRLKSGAYGDKpLNVDEKVWKKIM 191
Cdd:PLN00040 160 SIEKELLERLKSGTYGDI-YNFPSKSYNKVL 189
Ribosomal_L28e pfam01778
Ribosomal L28e protein family;
5-118 1.04e-50

Ribosomal L28e protein family;


Pssm-ID: 460323  Cd Length: 115  Bit Score: 163.46  E-value: 1.04e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 760012251    5 IVWQVI--NQSFcSHRIKAPNGQNFCRNEYNVTGLCTRQSCPLANSKYATVKCDNGKLYLYMKTPERAHTPAKLWERIKL 82
Cdd:pfam01778   1 LIWEIIrnNNSF-LVKTRTGNGQTFSREPYNLTGLCSRKYCGLANSKYATVREDGGGVYLYTKKAERAHKPAKLWEKITL 79
                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 760012251   83 SKNYTKALQQIDEHLLHWSKFFRHKCKQRFTKLTQV 118
Cdd:pfam01778  80 SKNYRKALKQIDNHLKGYRPDLRHAAKQRASAILQS 115
Mak16 pfam04874
Mak16 protein C-terminal region; The precise function of this eukaryotic protein family is ...
138-235 1.05e-30

Mak16 protein C-terminal region; The precise function of this eukaryotic protein family is unknown. The yeast orthologues have been implicated in cell cycle progression and biogenesis of 60S ribosomal subunits. The Schistosoma mansoni Mak16 has been shown to target protein transport to the nucleolus.


Pssm-ID: 461462  Cd Length: 97  Bit Score: 111.13  E-value: 1.05e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 760012251  138 APKVKRREQNRERKALVAAKIEKAIEKELMDRLKSGAYGDkPLNVDEKVWKKIMGQMEEENSQDEEEDWDEEEESDDGEV 217
Cdd:pfam04874   1 KKKVERREERRERKALAAAKLERAIEKELLERLKSGAYGD-PYNFPEEAWDKVLEQEELDEGEEEEEEEEEEEEEEEGEV 79
                          90
                  ....*....|....*...
gi 760012251  218 EYVADDGEGEYVDVDDLE 235
Cdd:pfam04874  80 EYVSDEEEDEDEEEEDLE 97
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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