|
Name |
Accession |
Description |
Interval |
E-value |
| leuS |
PRK12300 |
leucyl-tRNA synthetase; Reviewed |
47-961 |
0e+00 |
|
leucyl-tRNA synthetase; Reviewed
Pssm-ID: 237049 [Multi-domain] Cd Length: 897 Bit Score: 1524.80 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 47 LHAGHTRTFTIGDVVARHKRMLGYNVLYPMGFHVTGTPIVGLAELIANRDPQTMDVYERLHGIPGDILPTLDTPEKIVDY 126
Cdd:PRK12300 1 LHVGHGRTYTIGDVIARYKRMRGYNVLFPMAFHVTGTPILGIAERIARGDPETIELYKSLYGIPEEELEKFKDPEYIVEY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 127 FKRESEKAMRNIGYSIDWRRKFTTTDPTYKKFIEWQYIRLEEKGLIVKGSHPVKWCPNDNNPVEDHDILHGEEATIVEYT 206
Cdd:PRK12300 81 FSEEAKEDMKRIGYSIDWRREFTTTDPEYSKFIEWQFRKLKEKGLIVKGSHPVRYCPNDNNPVGDHDLLDGEEPEIVEYT 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 207 LIKF-RYKDLVLPCATLRPETTYGVTNLWVNPDVTYVKAKVtqgeNEEFWVVSKEAFRKLTFTDRTVEYIEDVPAKSIIG 285
Cdd:PRK12300 161 LIKFeESEDLILPAATLRPETIFGVTNLWVNPDATYVKAEV----DGEKWIVSKEAAEKLSFQDRDVEIIEEIKGSELIG 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 286 IKLTNPVTGDEIISLPASFVRPENGSGIVMSVPAHAPFDYLALRDLYDAdlseygiTEDLRNIKLISLIKVPEFGEFPAK 365
Cdd:PRK12300 237 KKVKNPVTGKEVPILPADFVDPDNGTGVVMSVPAHAPYDYVALRDLKKN-------KELLDVIEPIPLIEVEGYGEFPAK 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 366 EIVESMGITSQKDPKAEEATKIVYRREFHGGVLKELTGKYEGQAVSKIKDILTRDFISSNAGETFYEFSE-PVVCRCGTP 444
Cdd:PRK12300 310 EVVEKLGIKSQEDPELEEATKEVYRAEFHKGVLKENTGEYAGKPVREAREKITKDLIEKGIADIMYEFSNrPVYCRCGTE 389
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 445 CVVNMVKGQWFLNYSNPEWKAKVYKCLDEMRIIPEEYRVEFENKVDWLKDKACARRKGLGTRLPFDKEWLIESLGDSTIY 524
Cdd:PRK12300 390 CVVKVVKDQWFIDYSDPEWKELAHKALDNMEIIPEEYRKEFENTIDWLKDRACARRRGLGTRLPWDEEWIIESLSDSTIY 469
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 525 MSYYVIARFIENGELKIENLTLSFFDYVLLGKSDLAAASADTGLSPELLEEIRRHFNYWYPVDLRSSGKDLVPNHLLFFL 604
Cdd:PRK12300 470 MAYYTIAHKIREYGIKPEQLTPEFFDYVFLGKGDPEEVSKKTGIPKEILEEMREEFLYWYPVDWRHSGKDLIPNHLTFFI 549
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 605 FHHVALFEEEKWPKALAVNGFVSLEGQKMSKSKGPILTMESAVSKYGADITRMYILSTAEQTQDADWQRTGIESARRQVD 684
Cdd:PRK12300 550 FNHVAIFPEEKWPRGIVVNGFVLLEGKKMSKSKGNVIPLRKAIEEYGADVVRLYLTSSAELLQDADWREKEVESVRRQLE 629
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 685 RFYSFANSVIESGKRadlsTELKQIDHWILSRIQNYIRDTNAALYSIQTREAIQNSFFLLQNDVKWYQRRGGE---TLLY 761
Cdd:PRK12300 630 RFYELAKELIEIGGE----EELRFIDKWLLSRLNRIIKETTEAMESFQTRDAVQEAFYELLNDLRWYLRRVGEannKVLR 705
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 762 YVLDNWVRLMSPFTPHLCEEIWEAMGHKDPISLAQYPLYNEDLIDDGAELAEEMIKGTLEDVEEIIRVTKMTPQKVHLYT 841
Cdd:PRK12300 706 EVLEIWIRLLAPFTPHLAEELWHKLGGEGFVSLEKWPEPDESKIDEEAELAEEYVKRLIEDIREILKVAKIKPKKVYIYV 785
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 842 APAWKAEAIRCACEMQlecslEVGTLIKKLMANPDLKRFGKEIPKFVQKIVPEFKSGSADRYEILTgPNIDEQTLLKESI 921
Cdd:PRK12300 786 APDWKYEVLEIAAENG-----DVKEAIKELMKDEELRKHGKEVAKLAQKIVKEVLKLDKEVRKLIL-KNIDEEEVLEEAK 859
|
890 900 910 920
....*....|....*....|....*....|....*....|
gi 805387474 922 SFLEKEIGCPVEVHSADSPafDPEKKSRFAEPLRPAIYIE 961
Cdd:PRK12300 860 DFLEKELGVEVEIYGADDP--GKKKKKKKALPLKPAIYIE 897
|
|
| leuS_arch |
TIGR00395 |
leucyl-tRNA synthetase, archaeal and cytosolic family; The leucyl-tRNA synthetases belong to ... |
9-961 |
0e+00 |
|
leucyl-tRNA synthetase, archaeal and cytosolic family; The leucyl-tRNA synthetases belong to two families so broadly different that they are represented by separate models. This model includes both archaeal and cytosolic eukaryotic leucyl-tRNA synthetases; the eubacterial and mitochondrial forms differ so substantially that some other tRNA ligases score higher by this model than does any eubacterial LeuS. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273056 [Multi-domain] Cd Length: 938 Bit Score: 1162.28 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 9 EIEKKWQKKWNESQIFQAEPDKREKFFITIPYPYLNGNLHAGHTRTFTIGDVVARHKRMLGYNVLYPMGFHVTGTPIVGL 88
Cdd:TIGR00395 2 AIEKKWQKRWEEAHIFEADPDDREKFFLTMAYPYLNGVMHAGHCRTFTIPEVSARFERMKGKNVLFPLGFHVTGTPILGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 89 AELIANRDPQTMDVYERLHGIPGDILPTLDTPEKIVDYFKRESEKAMRNIGYSIDWRRKFTTTDPTYKKFIEWQYIRLEE 168
Cdd:TIGR00395 82 AELIKRRDELTIKNYTEVHAIPREELLKFTDPEYIVEYFSREAESACKSMGYSIDWRRSFKTTDPYYDRFIEWQMNKLKE 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 169 KGLIVKGSHPVKWCPNDNNPVEDHDILHGEEATIVEYTLIKFRYKD--LVLPCATLRPETTYGVTNLWVNPDVTYVKAKV 246
Cdd:TIGR00395 162 LGLIVKGEHPVRYCPKDGNPVEDHDLLSGEGVTIVEYILIKFELEDgaFYFVAATLRPETVYGVTNCWVNPTITYVIAEV 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 247 tqgeNEEFWVVSKEAFRKLTFTDRTVEYIEDVPAKSIIGIKLTNPVTGDEIISLPASFVRPENGSGIVMSVPAHAPFDYL 326
Cdd:TIGR00395 242 ----GGEKWITSKEAFENLSYQKLKYKPIEEVPGKQFIGKKVHNPVVGPEVPILPAEFVDTTKGTGVVMSVPAHAPDDYI 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 327 ALRDLyDADLSEYGITEDLRNIKLISLIKVPEFGEFPAKEIVESMGITSQKD-PKAEEATKIVYRREFHGGVLKELTGKY 405
Cdd:TIGR00395 318 ALEDL-LHDPEYLGIKPVVIDIEPVPLIHTDGYGDLPAKEIVEEKGIKSQKDkNLLEEATKILYKEEYHTGVMIYNIPPY 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 406 EGQAVSKIKDILTRDFISSNAGETFYEFSE-PVVCRCGTPCVVNMVKGQWFLNYSNPEWKAKVYKCLDEMRIIPEEYRVE 484
Cdd:TIGR00395 397 KGMKVSEAKEKVKADLIDAGLADVMYEFSEsPVICRCGTDCIVKVVEDQWFVKYSDESWKELAHECLEGMRIIPEEVKNA 476
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 485 FENKVDWLKDKACARRKGLGTRLPFDKEWLIESLGDSTIYMSYYVIARFIENGELKIENLTLSFFDYVLLGKSDLAAasa 564
Cdd:TIGR00395 477 FEGKIDWLKDWACCRRYGLGTRLPWDEKWLIESLSDSTIYMAYYTIAHYLNKDYYGNEQMTDEFFDYIFLGKGDVKN--- 553
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 565 dTGLSPELLEEIRRHFNYWYPVDLRSSGKDLVPNHLLFFLFHHVALFEEEKWPKALAVNGFVSLEGQKMSKSKGPILTME 644
Cdd:TIGR00395 554 -TNIPLPAIQKLRREFEYWYPLDWRISGKDLIPNHLTFYIFHHVAIFPEKFWPRGIVVNGYVMLEGKKMSKSKGNVLTLE 632
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 645 SAVSKYGADITRMYILSTAEQTQDADWQRTGIESARRQVDRFYSFANsviESGKRADLST--ELKQIDHWILSRIQNYIR 722
Cdd:TIGR00395 633 QAVEKFGADVARLYIADAAETVQDADWKESEVEGTILRLERLYEFAE---EITKESNLETgeETSFIDRWLESRMNAAIK 709
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 723 DTNAALYSIQTREAIQNSFFLLQNDVKWYQRRGGE---TLLYYVLDNWVRLMSPFTPHLCEEIWEAMGHKDPISLAQYPL 799
Cdd:TIGR00395 710 ETYEAMENFQTRKAVKYALFDLQADVDWYRRRGGVnhkDVLARYLETWIKLLAPFAPHFAEEMWEEVGNEGFVSLAKFPE 789
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 800 YNEDLIDDGAELAEEMIKGTLEDVEEIIRVTKMTPQKVHLYTAPAWKAEAIRCACEMQlecSLEVGTLIKKLMANPDLKR 879
Cdd:TIGR00395 790 ASEPAVDKEVEAAEEYLRNLVRDIQEIAKIDASKPKRVYLYTSEDWKSQCLKIVAELF---GEDTGEDMKKVMEEPEERK 866
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 880 FGKEIPKFVQKIVPEFKSGSADRyeiltgpnIDEQTLLKESISFLEKEIGCPVEVHSadSPAFDPEKKSRFAEPLRPAIY 959
Cdd:TIGR00395 867 RGKEVISLVKQIIKDEKKEDELQ--------ISEIEVLKAAARFIKKEVGALVIIEF--SADSFPENKKRNAVPGKPAIY 936
|
..
gi 805387474 960 IE 961
Cdd:TIGR00395 937 LE 938
|
|
| PLN02959 |
PLN02959 |
aminoacyl-tRNA ligase |
9-941 |
0e+00 |
|
aminoacyl-tRNA ligase
Pssm-ID: 215518 [Multi-domain] Cd Length: 1084 Bit Score: 555.06 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 9 EIEKKWQKKWNESQIFQAEPDKR-----EKFFITIPYPYLNGNLHAGHTRTFTIGDVVARHKRMLGYNVLYPMGFHVTGT 83
Cdd:PLN02959 17 EIEVAVQKWWEEEKVFEAEAGDEppkpgEKFFGNFPYPYMNGLLHLGHAFSLSKLEFAAAYHRLRGANVLLPFAFHCTGM 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 84 PIVGLAELIANRDPQ--------TMDVYE------------------------------------------RLHGIPGDI 113
Cdd:PLN02959 97 PIKASADKLAREIQQygnppvfpEEDEDEaaavaaakaeaeaaaappdkfkgkkskavaksgtqkyqweimRSFGLPDSE 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 114 LPTLDTPEKIVDYFKRESEKAMRNIGYSIDWRRKFTTTD--PTYKKFIEWQYIRLEEKGLIVKGSHPVKWCPNDNNPVED 191
Cdd:PLN02959 177 IAKFQDPYHWLSYFPPLAKEDLKAFGLGCDWRRSFITTDvnPYYDAFVRWQFRKLKKKGKIVKDKRYTIYSPLDGQPCAD 256
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 192 HDILHGEEATIVEYTLIKFRY-------------KDLVLPCATLRPETTYGVTNLWVNPDVTYvkaKVTQGENEEFWVVS 258
Cdd:PLN02959 257 HDRASGEGVGPQEYVLIKMEVlppfpgklkalegKKVFLAAATLRPETMYGQTNCWVLPDGKY---GAYEINDTEVFILT 333
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 259 KEAFRKLTFTDRT-----VEYIEDVPAKSIIGIKLTNPVTGDEII-SLPASFVRPENGSGIVMSVPAHAPFDYLALRDLY 332
Cdd:PLN02959 334 ARAALNLAYQNFSkvpgkPTCLVELTGYDLIGLPLKSPLAFNEVIyALPMLTILTDKGTGVVTSVPSDSPDDYMALSDLK 413
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 333 D-ADLSE-YGITED-LRNIKLISLIKVPEFGEFPAKEIVESMGITSQKDP-KAEEATKIVYRREFHGGVLkeLTGKYEGQ 408
Cdd:PLN02959 414 AkPALRAkYGVKDEwVLPFEVVPIINIPEFGDKSAEKVCEDLKIKSQNDKeKLAEAKRLTYLKGFTDGTM--LVGEYAGR 491
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 409 AVSKIKDILTRDFISSNAGETFYEFSEPVVCRCGTPCVVNMVKgQWFLNYSNPEWKAKVYKCLDEMRIIPEEYRVEFENK 488
Cdd:PLN02959 492 KVQEAKPLIKKKLIEAGQAILYSEPEKKVMSRSGDECVVALTD-QWYLTYGEEEWKKKAEKCLSKMNLYSDETRHGFEHT 570
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 489 VDWLKDKACARRKGLGTRLPFDKEWLIESLGDSTIYMSYYVIARFIENGEL--------KIENLTLSFFDYVLLGKSdla 560
Cdd:PLN02959 571 LGWLNQWACSRSFGLGTRIPWDEQFLIESLSDSTIYMAYYTVAHLLQGGDMygkdkssiKPEQMTDEVWDFVFCGGP--- 647
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 561 aASADTGLSPELLEEIRRHFNYWYPVDLRSSGKDLVPNHLLFFLFHHVALFEEEKWPKALAVNGFVSLEGQKMSKSKGPI 640
Cdd:PLN02959 648 -LPKSSDIPAELLEKMKQEFEYWYPFDLRVSGKDLIQNHLTFAIYNHTAIWAEEHWPRGFRCNGHLMLNSEKMSKSTGNF 726
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 641 LTMESAVSKYGADITRMYILSTAEQTQDADWQRTGIESARRQVDRFYSFANSVI--ESGKRADLSTELkqIDHWILSRIQ 718
Cdd:PLN02959 727 LTLRQAIEEFSADATRFALADAGDGVDDANFVFETANAAILRLTKEIAWMEEVLaaESSLRTGPPSTY--ADRVFENEIN 804
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 719 NYIRDTNAALYSIQTREAIQNSFFLLQNDVKWYQRRGGET-----LLYYVLDNWVRLMSPFTPHLCEEIWEAMGHKDPIS 793
Cdd:PLN02959 805 IAIAETEKNYEAMMFREALKSGFYDLQAARDEYRLSCGSGgmnrdLVWRFMDVQTRLITPICPHYAEHVWREILKKEGFA 884
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 794 L-AQYPLYNE-------------DLIDDGAELAEEMIKGTLEDVEEIIRVT-KMTPQKVHLYTA---PAWKAEAIRCace 855
Cdd:PLN02959 885 VtAGWPVAGEpdltlkrankylqDSIVSFRKLLQKQLAGSKKAKKGGAPVTlPEKKLAGLIYVAekyDGWKEECLRI--- 961
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 856 MQLECSLEVGTLIKKLMANPDLKR--FGKEIP-KFVQKIVPEFKSGSADRyEILTGPN-------IDEQTLLKESISFLE 925
Cdd:PLN02959 962 LQSKFDSQSRTFAPDAEILEALKEssVGQEANfKQVQKLCMPFVKFKKDE-AIAVGPQaldlklpFDEIEVLQENLELIK 1040
|
1050
....*....|....*..
gi 805387474 926 KEIGC-PVEVHSADSPA 941
Cdd:PLN02959 1041 RQLGLeEVEILSASDPD 1057
|
|
| valS |
TIGR00422 |
valyl-tRNA synthetase; The valyl-tRNA synthetase (ValS) is a class I amino acyl-tRNA ligase ... |
1-896 |
1.12e-85 |
|
valyl-tRNA synthetase; The valyl-tRNA synthetase (ValS) is a class I amino acyl-tRNA ligase and is particularly closely related to the isoleucyl tRNA synthetase. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273070 [Multi-domain] Cd Length: 861 Bit Score: 294.27 E-value: 1.12e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 1 MEQDYKPHEIEKKWQKKWNESQIFQAEPDK-REKFFITIPYPYLNGNLHAGHTRTFTIGDVVARHKRMLGYNVLYPMGFH 79
Cdd:TIGR00422 1 MPKDYDPHEVEKKWYKKWEKSGFFKPDGNSnKPPFCIDIPPPNVTGSLHIGHALNWSIQDIIARYKRMKGYNVLWLPGTD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 80 VTGTPivglaelianrdpqTMDVYERLHGIPG---DILPTLDTPEKIVDyFKRESEKAMRN----IGYSIDWRRKFTTTD 152
Cdd:TIGR00422 81 HAGIA--------------TQVKVEKKLGAEGktkHDLGREEFREKIWE-WKEESGGTIKNqikrLGASLDWSRERFTMD 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 153 PTYKKFIEWQYIRLEEKGLIVKGSHPVKWCPNDNNPVEDHDILHGEeatiVEYTLIKFRYK-------DLVLpcATLRPE 225
Cdd:TIGR00422 146 EGLSKAVKEAFVRLYEKGLIYRGEYLVNWDPKLNTAISDIEVEYKE----VKGKLYYIRYPlangskdYLVV--ATTRPE 219
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 226 TTYGVTNLWVNPDvtyvkakvtqgeneefwvvskeafrkltftdrtveyieDVPAKSIIGIKLTNPVTGDEIISLPASFV 305
Cdd:TIGR00422 220 TMFGDTAVAVHPE--------------------------------------DERYKHLIGKKVILPLTGRKIPIIADEYV 261
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 306 RPENGSGIVMSVPAHAPFDYlalrdlydadlsEYGITEDLRNIKLISlikvpefgefpakeivesmgitsqkdpkaeeat 385
Cdd:TIGR00422 262 DMEFGTGAVKVTPAHDFNDY------------EWGKRHNLEFINILD--------------------------------- 296
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 386 kivyrrefHGGVLKELTGKYEGQAVSKIKDILTRDFISsnagETFYEFSEPV-----VC-RCGTPcVVNMVKGQWFLNYs 459
Cdd:TIGR00422 297 --------EDGLLNENAGKYQGLTRFEARKKIVEDLKE----EGLLVKIEPHthnvgTCwRSGTV-VEPLLSKQWFVKV- 362
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 460 nPEWKAKVYKCLDE--MRIIPEEYRVEFENKVDWLKDKACARRKGLGTRLPFdkeWLIESLGDstiymsyYVIARfiENG 537
Cdd:TIGR00422 363 -EKLADKALEAAEEgeIKFVPKRMEKRYLNWLRNIKDWCISRQLIWGHRIPV---WYCKECGE-------VYVAK--EEP 429
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 538 ELKIENLTLSFFDYVllGKSDLAAASADTGLSP------ELLEEIRRHFnywYPVDLRSSGKDlvpnhLLFF-----LFH 606
Cdd:TIGR00422 430 LPDDKTNTGPSVELE--QDTDVLDTWFSSSLWPfstlgwPDETKDLKKF---YPTDLLVTGYD-----IIFFwvarmIFR 499
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 607 HVALFEEEKWpKALAVNGFVSLE-GQKMSKSKGPILTMESAVSKYGADITRMYILSTAEQTQDADWQRTGIESARRQVDR 685
Cdd:TIGR00422 500 SLALTGQVPF-KEVYIHGLVRDEqGRKMSKSLGNVIDPLDVIEKYGADALRFTLASLVTPGDDINFDWKRVESARNFLNK 578
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 686 FYSFANSVI--ESGKRADLSTELKQ--IDHWILSRIQNYIRDTNAALYSIQTREAIQNSFFLLQNDV-KWY--------- 751
Cdd:TIGR00422 579 LWNASRFVLmnLSDDLELSGGEEKLslADRWILSKLNRTIKEVRKALDKYRFAEAAKALYEFIWNDFcDWYielvkyrly 658
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 752 -----QRRGGETLLYYVLDNWVRLMSPFTPHLCEEIWEAMGHK-DPISLAQYPLYNEDLIDDGAELAEEMIKGTLEDVEE 825
Cdd:TIGR00422 659 ngneaEKKAARDTLYYVLDKALRLLHPFMPFITEEIWQHFKEGaDSIMLQSYPVVDAEFVDEEAEKAFELLKEIIVSIRN 738
|
890 900 910 920 930 940 950
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 805387474 826 IirvtkmtpqKVHLYTAPAWKAEAIRCACEMQLECSLEVGTLIKKLMANPDLKRFGKEIPKF---VQKIVPEFK 896
Cdd:TIGR00422 739 L---------KAESNIPPNAPLKVLLIYTEAETAERLKLNAVDIKGAINFSEVEVVIEKPEVteaVVELVPGFE 803
|
|
| LeuRS_core |
cd00812 |
catalytic core domain of leucyl-tRNA synthetases; Leucyl tRNA synthetase (LeuRS) catalytic ... |
449-671 |
4.23e-76 |
|
catalytic core domain of leucyl-tRNA synthetases; Leucyl tRNA synthetase (LeuRS) catalytic core domain. This class I enzyme is a monomer which aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. In Aquifex aeolicus, the gene encoding LeuRS is split in two, just before the KMSKS motif. Consequently, LeuRS is a heterodimer, which likely superimposes with the LeuRS monomer found in most other organisms. LeuRS has an insertion in the core domain, which is subject to both deletions and rearrangements and thus differs between prokaryotic LeuRS and archaeal/eukaryotic LeuRS. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids.
Pssm-ID: 173906 [Multi-domain] Cd Length: 314 Bit Score: 251.78 E-value: 4.23e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 449 MVKGQWFLNYSNPEWKAKVYKCLDEMRIIPEEYRVEFENKVDwlkdkaCARRKGLGTRLPFdkEWLIESLGDSTIYMSYY 528
Cdd:cd00812 127 KLLDQWFLKYSETEWKEKLLKDLEKLDGWPEEVRAMQENWIG------CSRQRYWGTPIPW--TDTMESLSDSTWYYARY 198
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 529 VIARFIENGELKIenltlsffdyvllgksdlaaasadtglspelLEEIRRHFNYWYPVDLRSSGKDLVPNHLLFFLFHHV 608
Cdd:cd00812 199 TDAHNLEQPYEGD-------------------------------LEFDREEFEYWYPVDIYIGGKEHAPNHLLYSRFNHK 247
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 805387474 609 ALFEEE----KWPKALAVNGFVSLEGQKMSKSKGPILTMESAVSKYGADITRMYILSTAEQTQDADW 671
Cdd:cd00812 248 ALFDEGlvtdEPPKGLIVQGMVLLEGEKMSKSKGNVVTPDEAIKKYGADAARLYILFAAPPDADFDW 314
|
|
| LeuS |
COG0495 |
Leucyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Leucyl-tRNA ... |
1-812 |
2.15e-69 |
|
Leucyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Leucyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 440261 [Multi-domain] Cd Length: 826 Bit Score: 247.66 E-value: 2.15e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 1 MEQDYKPHEIEKKWQKKWNESQIFQA-EPDKREKFFITIPYPYLNGNLHAGHTRTFTIGDVVARHKRMLGYNVLYPMGFH 79
Cdd:COG0495 1 MQERYNPKEIEKKWQKYWEENGTFKAdEDSSKPKYYVLDMFPYPSGRLHMGHVRNYTIGDVVARYKRMQGYNVLHPMGWD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 80 VTGTPivglAELIAnrdpqtMDvyerlHGIPgdilPTLDTPEKIvDYFKREsekaMRNIGYSIDWRRKFTTTDPTYKKFI 159
Cdd:COG0495 81 AFGLP----AENAA------IK-----NGVH----PAEWTYENI-ANMRRQ----LKRLGLSYDWSREIATCDPEYYKWT 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 160 EWQYIRLEEKGLIVKGSHPVKWCPND-----------------NNPVE--------------------DHDIL------- 195
Cdd:COG0495 137 QWIFLQLYEKGLAYRKEAPVNWCPVDqtvlaneqvidgrcwrcGAPVEkkelpqwflkitdyadelldDLDKLdgwpekv 216
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 196 -----------HGEEativeytlIKFRYKDL--VLPCATLRPETTYGVTNLWVNPDVTYVKAKVTQGENEEFwvvskEAF 262
Cdd:COG0495 217 ktmqrnwigrsEGAE--------VDFPVEGSdeKITVFTTRPDTLFGATFMVLAPEHPLVKELATPEQNAAV-----AAF 283
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 263 ----RKLTFTDRTVEYIEdvpaKS--IIGIKLTNPVTGDEIislP---ASFVRPENGSGIVMSVPAHapfDylaLRDLYD 333
Cdd:COG0495 284 ieeaKKKSEIERTSETKE----KTgvFTGLYAINPLTGEKI---PiwiADYVLMDYGTGAVMAVPAH---D---QRDFEF 350
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 334 AdlSEYGItedlrniklislikvpefgefPAKEIVESmgitsqKDPKAEEATKIVYRREfhgGVL---KELTGKYEGQAV 410
Cdd:COG0495 351 A--KKYGL---------------------PIKQVIAP------EDGDDPDILEEAYTGD---GVLinsGEFDGLDSEEAK 398
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 411 SKIKDILT-------------RDFISSNA---GETFyefsePVV-CRCGTPCVVnmvkgqwflnysnPEwkakvykclDE 473
Cdd:COG0495 399 EAIIEWLEekglgkrkvnyrlRDWLISRQrywGEPI-----PIIhCEDCGVVPV-------------PE---------DQ 451
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 474 MRII-PE--EYRVEFEN---KV-DWLK--DKAC---ARRkglgtrlpfdkE------WlIESlgdstiymS-YYviARFI 534
Cdd:COG0495 452 LPVElPEdvDFDPTGGSplaRApEWVNvtCPKCggpARR-----------EtdtmdtF-VDS--------SwYY--LRYT 509
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 535 engelkienltlsffdyvllgksdlaAASADTG-LSPELLeeirrhfNYWYPVD----------LrssgkdlvpnHLLFF 603
Cdd:COG0495 510 --------------------------DPHNDEApFDPEAA-------NYWLPVDqyiggiehaiL----------HLLYA 546
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 604 LFHHVAL-------FEEekwP----------KALAVNGFVSLEGQKMSKSKGPILTMESAVSKYGADITRMYILSTAEQT 666
Cdd:COG0495 547 RFFTKVLrdlglvsFDE---PfkrlltqgmvLEVGKDGVVIGGIEKMSKSKGNVVDPDEIIEKYGADTLRLFEMFAGPPE 623
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 667 QDADWQRTGIESARRQVDRFYSFANSVIESGKR--ADLSTELKQID---HWILSRIQNYIRDTN-----AALYSI--QTR 734
Cdd:COG0495 624 RDLEWSDSGVEGAYRFLNRVWRLVVDEAEALKLdvADLSEADKELRralHKTIKKVTEDIERLRfntaiAALMELvnALY 703
|
890 900 910 920 930 940 950
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 805387474 735 EAIQNSffllqndvkwyqrRGGETLLYYVLDNWVRLMSPFTPHLCEEIWEAMGHKDPISLAQYPLYNED-LIDDGAELA 812
Cdd:COG0495 704 KAKDSG-------------EADRAVLREALETLVLLLAPFAPHIAEELWERLGHEGSVADAPWPEADEAaLVEDEVTIV 769
|
|
| valS |
PRK13208 |
valyl-tRNA synthetase; Reviewed |
1-820 |
1.11e-63 |
|
valyl-tRNA synthetase; Reviewed
Pssm-ID: 237306 [Multi-domain] Cd Length: 800 Bit Score: 230.85 E-value: 1.11e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 1 MEQDYKPHEIEKKWQKKWNESQIFQAEPDKREK-FFITIPYPYLNGNLHAGHTRTFTIGDVVARHKRMLGYNVLYPMGFH 79
Cdd:PRK13208 6 LPKKYDPEELEEKWQKIWEEEGTYKFDPDERKPvYSIDTPPPTVSGSLHIGHVFSYTHTDFIARYQRMRGYNVFFPQGWD 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 80 VTGTPIvglaelianrdpqtmdvyERL----HGIPGDILPT---LDTPEKIVDYFKRESEKAMRNIGYSIDWRRKFTTTD 152
Cdd:PRK13208 86 DNGLPT------------------ERKvekyYGIRKDDISReefIELCRELTDEDEKKFRELWRRLGLSVDWSLEYQTIS 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 153 PTYKKFIEWQYIRLEEKGLIVKGSHPVKWCPNDNNPVEDHDILHGEEATIVEYtlIKFRYKD-LVLPCATLRPETTYGVT 231
Cdd:PRK13208 148 PEYRRISQKSFLDLYKKGLIYRAEAPVLWCPRCETAIAQAEVEYREREGKLNY--IKFPVEDgEEIEIATTRPELLPACV 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 232 NLWVNPDvtyvkakvtqgeneefwvvskeafrkltfTDRtveYiedvpaKSIIGIKLTNPVTGDEIISLPASFVRPENGS 311
Cdd:PRK13208 226 AVVVHPD-----------------------------DER---Y------KHLVGKTAIVPLFGVEVPILADPLVDPDFGT 267
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 312 GIVMsvpahapfdylalrdlydadLSEYGITEDLR-----NIKLISLIkvpefgefpakeivesmgitsQKDpkaeeatk 386
Cdd:PRK13208 268 GAVM--------------------ICTFGDKTDVTwwrelNLPTRIII---------------------DED-------- 298
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 387 ivyrrefhgGVLKELTGKYEG----QAVSKIKDIL-TRDF------ISSNAGetFYEfsepvvcRCGTPCVVnMVKGQWF 455
Cdd:PRK13208 299 ---------GRMTEAAGKLAGltieEARKKIVEDLkSGGLlgkqepIKHNVK--FCE-------RCDTPLEI-LVTRQWF 359
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 456 LNYsnPEWKAKVYKCLDEMRIIPEEYRVEFENKV-----DWLkdkaCARRKGLGTRLPF------------DKEWL-IES 517
Cdd:PRK13208 360 IKV--LDLKEELLERGKEINWYPEHMRVRLENWIeglnwDWC----ISRQRYFGTPIPVwyckdcghpilpDEEDLpVDP 433
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 518 LGDStiymsyyviARFIENGELKIENLTlsffdyvllGKSDLAAASADTGLSPELL---EEIRRHFNYWYPVDLRSSGKD 594
Cdd:PRK13208 434 TKDE---------PPGYKCPQCGSPGFE---------GETDVMDTWATSSITPLIVtgwERDEDLFEKVFPMDLRPQGHD 495
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 595 LVPnhllFFLFHHV----ALFEEEKWpKALAVNGFVSLE-GQKMSKSKGPILTMESAVSKYGADITRmYILSTAEQTQDA 669
Cdd:PRK13208 496 IIR----TWLFYTIlrayLLTGKLPW-KNIMISGMVLDPdGKKMSKSKGNVVTPEELLEKYGADAVR-YWAASARLGSDT 569
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 670 --DWQrtGIESARRQVDRFYS---FAnSVIESGKRADLSTELKQIDHWILSRIQNYIRDTNAALYSIQ---TREAIQnSF 741
Cdd:PRK13208 570 pfDEK--QVKIGRRLLTKLWNasrFV-LHFSADPEPDKAEVLEPLDRWILAKLAKVVEKATEALENYDfakALEEIE-SF 645
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 742 FL--------------LQNDVKWYQRRGGETLLYYVLDNWVRLMSPFTPHLCEEIWEAMgHKDPISLAQYPLYNEDLIDD 807
Cdd:PRK13208 646 FWhvfcddylelvksrAYGEDEEEEQKSARYTLYTVLDTLLRLLAPFLPFITEEVWSWL-YGGSVHRASWPEPDEELIDE 724
|
890
....*....|...
gi 805387474 808 GAELAEEMIKGTL 820
Cdd:PRK13208 725 EDEELGELAKEIL 737
|
|
| LeuRS_core |
cd00812 |
catalytic core domain of leucyl-tRNA synthetases; Leucyl tRNA synthetase (LeuRS) catalytic ... |
33-182 |
3.00e-58 |
|
catalytic core domain of leucyl-tRNA synthetases; Leucyl tRNA synthetase (LeuRS) catalytic core domain. This class I enzyme is a monomer which aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. In Aquifex aeolicus, the gene encoding LeuRS is split in two, just before the KMSKS motif. Consequently, LeuRS is a heterodimer, which likely superimposes with the LeuRS monomer found in most other organisms. LeuRS has an insertion in the core domain, which is subject to both deletions and rearrangements and thus differs between prokaryotic LeuRS and archaeal/eukaryotic LeuRS. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids.
Pssm-ID: 173906 [Multi-domain] Cd Length: 314 Bit Score: 202.86 E-value: 3.00e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 33 KFFITIPYPYLNGNLHAGHTRTFTIGDVVARHKRMLGYNVLYPMGFHVTGTPIVGLAELIANrdpqtmdvyerlhgipgd 112
Cdd:cd00812 1 KFYILVMFPYPSGALHVGHVRTYTIGDIIARYKRMQGYNVLFPMGFDAFGLPAENAAIKIGR------------------ 62
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 113 ilptldTPEKIVDYFKRESEKAMRNIGYSIDWRRKFTTTDPTYKKFIEWQYIRLEEKGLIVKGSHPVKWC 182
Cdd:cd00812 63 ------DPEDWTEYNIKKMKEQLKRMGFSYDWRREFTTCDPEYYKFTQWLFLKLYEKGLAYKKEAPVNWC 126
|
|
| tRNA-synt_1 |
pfam00133 |
tRNA synthetases class I (I, L, M and V); Other tRNA synthetase sub-families are too ... |
13-662 |
2.10e-52 |
|
tRNA synthetases class I (I, L, M and V); Other tRNA synthetase sub-families are too dissimilar to be included.
Pssm-ID: 459685 [Multi-domain] Cd Length: 602 Bit Score: 194.17 E-value: 2.10e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 13 KWQKKWNESQIFQAEPDKR---EKFFITIPYPYLNGNLHAGHTRTFTIGDVVARHKRMLGYNVLYPMGFHVTGTPIvgla 89
Cdd:pfam00133 1 QIYEFWDEQGYFKPELEKRkgkPSFTIHDGPPNATGSLHIGHALAKTLKDIVIRYKRMKGYYVLWVPGWDHHGLPT---- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 90 ELianrdpqtmdVYERLHGIPG-DILPTLDTPE------KIVDYFKRESEKAMRNIGYSIDWRRKFTTTDPTYKKFIEWQ 162
Cdd:pfam00133 77 EQ----------VVEKKLGIKEkKTRHKYGREEfrekcrEWKMEYADEIRKQFRRLGRSIDWDREYFTMDPELEAAVWEV 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 163 YIRLEEKGLIVKGSHPVKWCPNDNNPVEDHDILHGEeatiVEYTLIKFRY-----KDLVLPCATLRPETTYGVTNLWVNP 237
Cdd:pfam00133 147 FVRLHDKGLIYRGKKLVNWSPALNTALSNLEVEYKD----VKGPSIHVAFpladdEGASLVIWTTTPWTLPGNTAVAVNP 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 238 DVTYVKakvtqgeNEEFWVVSKEAFRKLTFTDRTVEYIEDVPAKSIIGIKLTNPVTGDEIISLPASFVRPENGSGIVMSV 317
Cdd:pfam00133 223 EFDYVI-------TGEGYILAEALLKSLYKKGTDKKILEDFRGKELEGKEAIHPFVNREIPIITDDYVDMEFGTGAVHIA 295
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 318 PAHAPFDYLALRDlydadlseygitedlRNIKLISLIkvpefgefpakeivesmgitsqkDPKaeeatkivyrrefhgGV 397
Cdd:pfam00133 296 PAHGENDYEVGQR---------------HNLEVINPV-----------------------DDD---------------GT 322
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 398 LKELTGKYEGQAVSKIKDILTRDFISSNA--GETFYEFSEPVVCRCGTPcVVNMVKGQWFLNYSnpEWKAKVYKCLDEMR 475
Cdd:pfam00133 323 FTEEAPDFQGVYRFDARKKIVELLTEKGLllKIEPFTHSYPFCWRSGTP-IIPRATPQWFVRMD--ELADQALEAVEKVQ 399
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 476 IIPEEYRVEFENKVDWLKDKACARRKGLGTRLPFdkeWLIESLGDSTIYMSYYVIARFIENGELKIENLTLSFFDYVLLG 555
Cdd:pfam00133 400 FVPKSGEKRYFNWLANIQDWCISRQRWWGHPIPA---WVSKDTEEVVCRGELFELVAGRFEEEGSIKWLHREAKDKLGYG 476
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 556 KSDLAAASA------DTGLSP----ELLEEIRRHFNYWYPVDLRSSGKDlvpnhLLFFLFHH-----VALFEEEKWpKAL 620
Cdd:pfam00133 477 KGTLEQDEDvldtwfSSGSWPfstlGWPFVNTEEFKKFFPADMLLEGSD-----QTRGWFYRmimlsTALTGSVPF-KNV 550
|
650 660 670 680
....*....|....*....|....*....|....*....|...
gi 805387474 621 AVNGFV-SLEGQKMSKSKGPILTMESAVSKYGADITRMYILST 662
Cdd:pfam00133 551 LVHGLVrDEQGRKMSKSLGNVIDPLDVIDKYGADALRLWLANS 593
|
|
| IleS |
COG0060 |
Isoleucyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Isoleucyl-tRNA ... |
5-815 |
1.93e-49 |
|
Isoleucyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Isoleucyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439830 [Multi-domain] Cd Length: 931 Bit Score: 189.91 E-value: 1.93e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 5 YKPHEIEKKWQKKWNESQIFQ---AEPDKREKFFItipY---PYLNGNLHAGHTRTFTIGDVVARHKRMLGYNVLYPMGF 78
Cdd:COG0060 16 ANLPKREPEILKFWEENDIYEksrEARAGRPKFVL---HdgpPYANGDIHIGHALNKILKDIIVRYKTMRGFDVPYVPGW 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 79 --HvtGTPIvglaELIAnrdpqtmdvyERLHGIPGDILPTLDtPEKIV---------------DYFKResekamrnIGYS 141
Cdd:COG0060 93 dcH--GLPI----ELKV----------EKELGIKKKDIEKVG-IAEFRekcreyalkyvdeqrEDFKR--------LGVW 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 142 IDWRRKFTTTDPTY--------KKFIewqyirleEKGLIVKGSHPVKWCPND-----NNPVEDHDIlhgEEATIVeytlI 208
Cdd:COG0060 148 GDWDNPYLTMDPEYeesiwwalKKLY--------EKGLLYKGLKPVPWCPRCgtalaEAEVEYKDV---TSPSIY----V 212
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 209 KFRYKDlvlPCATLRPETTYGV---TNLW---------VNPDVTYVKAKVTqgeNEEFWVVSKE----AFRKLTFTDRTV 272
Cdd:COG0060 213 KFPVKD---EKALLLLEDAYLViwtTTPWtlpanlavaVHPDIDYVLVEVT---GGERLILAEAlveaVLKELGIEDYEV 286
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 273 eyIEDVPAKSIIGIKLTNP---VTGDEIIS--LPASFVRPENGSGIVMSVPAHAPFDYLALRdlydadlsEYGItedlrn 347
Cdd:COG0060 287 --LATFKGAELEGLRYEHPfyyVVGYDRAHpvILGDYVTTEDGTGIVHTAPGHGEDDFEVGK--------KYGL------ 350
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 348 iklislikvpefgefpakEIVESMgitsqkDPKaeeatkivyrrefhgGVLKELTGKYEGQAVSKIKDILTRDFISSNA- 426
Cdd:COG0060 351 ------------------PVLNPV------DDD---------------GRFTEEAPLFAGLFVKDANPAIIEDLKERGAl 391
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 427 -GETFYEFSEPvVC-RCGTPcVVNMVKGQWFlnYSNPEWKAKVYKCLDEMRIIPEEYRVEF----ENKVDW--------- 491
Cdd:COG0060 392 lAREKITHSYP-HCwRCKTP-LIYRATPQWF--ISMDKLRDRALEAIEKVNWIPEWGEGRFgnmlENRPDWcisrqrywg 467
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 492 -----LKDKACarrkglgTRLPFDKEwLIESlgdstiymsyyVIARFIENGELKIENLTLS--FFDyvllgksdlaaasa 564
Cdd:COG0060 468 vpipiWVCEDC-------GELHRTEE-VIGS-----------VAELLEEEGADAWFELDLHrpFLD-------------- 514
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 565 DTGLSPELLEEIRR--------------HF-------NYWYPVDL--------R----SSgkdlvpnHLLfflfhHVALF 611
Cdd:COG0060 515 ETLKCPKCGGTMRRvpdvldvwfdsgsmHFavlenreELHFPADFylegsdqtRgwfySS-------LLT-----STALF 582
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 612 EEEkwP-KALAVNGFVsL--EGQKMSKSKGPILTMESAVSKYGADITRMYILSTAeQTQDadwQRTGIESARRQVDRF-- 686
Cdd:COG0060 583 GRA--PyKNVLTHGFV-LdeDGRKMSKSLGNVVDPQEVIDKYGADILRLWVASSD-YWGD---LRFSDEILKEVRDVYrr 655
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 687 ----YSFANSVIE--SGKRADLST-ELKQIDHWILSRIQNYIRDTNAALYSIQTREAIQ--NSFflLQNDV-KWY----- 751
Cdd:COG0060 656 lrntYRFLLANLDdfDPAEDAVPYeDLPELDRWILSRLNELIKEVTEAYDNYDFHRAYRalHNF--CVEDLsNWYldisk 733
|
890 900 910 920 930 940 950
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 805387474 752 -----------QRRGGETLLYYVLDNWVRLMSPFTPHLCEEIWEAMGHKDPIS--LAQYPLYNEDLIDDgaELAEEM 815
Cdd:COG0060 734 drlyteaadslDRRAAQTTLYEVLETLVRLLAPILPFTAEEIWQNLPGEAEESvhLADWPEVDEELIDE--ELEAKW 808
|
|
| valS |
PRK05729 |
valyl-tRNA synthetase; Reviewed |
1-928 |
2.77e-41 |
|
valyl-tRNA synthetase; Reviewed
Pssm-ID: 235582 [Multi-domain] Cd Length: 874 Bit Score: 164.12 E-value: 2.77e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 1 MEQDYKPHEIEKKWQKKWNESQIFQAEPDKREKFFITIPYPYLNGNLHAGHTRTFTIGDVVARHKRMLGYNVLYpmgfhV 80
Cdd:PRK05729 5 LPKTYDPKEVEAKWYQKWEEKGYFKPDDNSKKPFSIVIPPPNVTGSLHMGHALNNTLQDILIRYKRMQGYNTLW-----L 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 81 TGTPIVGLAelianrdpqTMDVYERL---HGI-PGDIlptldTPEKIVDY---FKRESEKA----MRNIGYSIDWRR-KF 148
Cdd:PRK05729 80 PGTDHAGIA---------TQMVVERQlaaEGKsRHDL-----GREKFLEKvweWKEESGGTitnqLRRLGASCDWSReRF 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 149 TTtDPTYKK-----FIewqyiRLEEKGLIVKGSHPVKWCPNDNNPVEDhdilhgEEatiVEYTLIK-----FRYKdLV-- 216
Cdd:PRK05729 146 TM-DEGLSKavrevFV-----RLYEKGLIYRGKRLVNWDPKLQTALSD------LE---VEYKEVKgklwhIRYP-LAdg 209
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 217 ---LPCATLRPETTYGVTNLWVNPdvtyvkakvtqgeneefwvvskeafrkltftdrtveyiEDVPAKSIIGIKLTNPVT 293
Cdd:PRK05729 210 sdyLVVATTRPETMLGDTAVAVNP--------------------------------------EDERYKHLIGKTVILPLV 251
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 294 GDEIISLPASFVRPENGSGIVMSVPAHAPFDY-LALRdlydadlseygitedlRNIKLISLIkvpefgefpakeivesmg 372
Cdd:PRK05729 252 GREIPIIADEYVDPEFGTGAVKITPAHDPNDFeVGKR----------------HNLPMINIM------------------ 297
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 373 itsqkDPKaeeatkivyrrefhgGVLKELTGKYEGQ-----------------AVSKIKDILtrdfisSNAGetfyeFSE 435
Cdd:PRK05729 298 -----DED---------------GTINENPGEYQGLdrfearkaivadleelgLLVKIEPHT------HSVG-----HSD 346
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 436 pvvcRCGTPcVVNMVKGQWFLNYSNpewKAKvyKCLD-----EMRIIPEE----YRVEFENKVDWlkdkaCARRKgL--G 504
Cdd:PRK05729 347 ----RSGVV-IEPYLSDQWFVKMKP---LAK--PALEavengEIKFVPERwektYFHWMENIQDW-----CISRQ-LwwG 410
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 505 TRLP--FDKewlieslgDSTIYMSyyviarfiENGELKIENLTLSFFDYVLlgksdlaaasaDT----GLSP-------E 571
Cdd:PRK05729 411 HRIPawYDE--------DGEVYVG--------REEPEAREKALLTQDEDVL-----------DTwfssALWPfstlgwpE 463
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 572 LLEEirrhFNYWYPVDLRSSGKDLvpnhlLFFL----------------FHHV---ALFEEEKwpkalavngfvsleGQK 632
Cdd:PRK05729 464 KTED----LKRFYPTSVLVTGFDI-----IFFWvarmimmglhftgqvpFKDVyihGLVRDEQ--------------GRK 520
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 633 MSKSKG----PILTMEsavsKYGADITRMYILSTAEQTQDA--DWQRtgIESARrqvdrfySFAN------------SVI 694
Cdd:PRK05729 521 MSKSKGnvidPLDLID----KYGADALRFTLAALASPGRDIrfDEER--VEGYR-------NFANklwnasrfvlmnLEG 587
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 695 ESGKRADLSTELKQIDHWILSRIQNYIRDTNAAL----YSIQTReAIQNsFFLlqNDV-KWY-----------QRRGGET 758
Cdd:PRK05729 588 ADVGELPDPEELSLADRWILSRLNRTVAEVTEALdkyrFDEAAR-ALYE-FIW--NEFcDWYlelakpvlqeaAKRATRA 663
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 759 LLYYVLDNWVRLMSPFTPHLCEEIWEAMGH---KDPISLAQYPLYNEDLIDDgaelAEEMIkgtlEDVEEIIR------- 828
Cdd:PRK05729 664 TLAYVLEQILRLLHPFMPFITEELWQKLAPlgiEESIMLAPWPEADEAIDEA----AEAEF----EWLKELITairnira 735
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 829 ---VTKMTPQKVHLYTAPAWKAEAIRcacemqlecslEVGTLIKKLmANPDLKRFGKEIPKF----VQKIVPEFKsgsad 901
Cdd:PRK05729 736 emnIPPSKKLPLLLKGADAEDRARLE-----------ANEAYIKRL-ARLESLEILADDEEApegaASAVVGGAE----- 798
|
1050 1060 1070
....*....|....*....|....*....|
gi 805387474 902 rYEILTGPNID---EQTLLKESISFLEKEI 928
Cdd:PRK05729 799 -LFLPLEGLIDveaELARLEKELAKLEKEI 827
|
|
| valS |
PRK14900 |
valyl-tRNA synthetase; Provisional |
5-826 |
3.68e-41 |
|
valyl-tRNA synthetase; Provisional
Pssm-ID: 237855 [Multi-domain] Cd Length: 1052 Bit Score: 164.39 E-value: 3.68e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 5 YKPHEIEKKWQKKWNESQIFQAE--PDKREKFFITIPYPYLNGNLHAGHTRTFTIGDVVARHKRMLGYNVLYpmgfhVTG 82
Cdd:PRK14900 19 YEHREVEARWYPFWQERGYFHGDehDRTRPPFSIVLPPPNVTGSLHLGHALTATLQDVLIRWKRMSGFNTLW-----LPG 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 83 TPIVGLA-ELIANRDPQTMDVYERlH--GIPGDILPTLDTPEKivdYFKRESEKaMRNIGYSIDWRRKFTTTDPTYKKFI 159
Cdd:PRK14900 94 TDHAGIAtQMIVEKELKKTEKKSR-HdlGREAFLERVWAWKEQ---YGSRIGEQ-HKALGASLDWQRERFTMDEGLSRAV 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 160 EWQYIRLEEKGLIVKGSHPVKWCPNDNNPVEDHDILHgEEATIVEytLIKFRYK----DLVLPCATLRPETTYGVTNLWV 235
Cdd:PRK14900 169 REVFVRLHEEGLIYREKKLINWCPDCRTALSDLEVEH-EEAHQGE--LWSFAYPladgSGEIVVATTRPETMLGDTAVAV 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 236 NPDvtyvkakvtqgeneefwvvskeafrkltftdrtveyieDVPAKSIIGIKLTNPVTGDEI-ISLPASFVRPENGSGIV 314
Cdd:PRK14900 246 HPL--------------------------------------DPRYMALHGKKVRHPITGRTFpIVADAILVDPKFGTGAV 287
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 315 MSVPAHAPFDYlalrdlydadlsEYGITEDLRNIKLIslikvpefgefpakeivesmgitsqkDPKAEeatkivyrrefh 394
Cdd:PRK14900 288 KVTPAHDFNDF------------EVGKRHGLEMITVI--------------------------GPDGR------------ 317
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 395 ggvLKELTGKYEG----QAVSKIKDILtrdfissnAGETFYEFSEPVV-----CRCGTPCVVNMVKGQWFLN---YSNPE 462
Cdd:PRK14900 318 ---MTAEAGPLAGldrfEARKEVKRLL--------AEQGLDRGAKPHVlplgrCQRSATILEPLLSDQWYVRiepLARPA 386
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 463 WKAkVYKclDEMRIIPEE----YRVEFENKVDWlkdkACARRKGLGTRLPfdkEWLIESlGDSTIYMSYYVIARFIENGE 538
Cdd:PRK14900 387 IEA-VEQ--GRTRFIPEQwtntYMAWMRNIHDW----CISRQLWWGHQIP---AWYCPD-GHVTVARETPEACSTCGKAE 455
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 539 LKI-ENLTLSFFDYVLLGKSDLAAasadtglsPELLEEIRRhfnyWYPVDLRSSGKDLVpnhllFFLFHHVAL----FEE 613
Cdd:PRK14900 456 LRQdEDVLDTWFSSGLWPFSTMGW--------PEQTDTLRT----FYPTSVMETGHDII-----FFWVARMMMmglhFMG 518
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 614 EKWPKALAVNGFVSLE-GQKMSKSKGPILTMESAVSKYGADITRMYILSTAEQTQDadwqrtgIESARRQVDRFYSFANS 692
Cdd:PRK14900 519 EVPFRTVYLHPMVRDEkGQKMSKTKGNVIDPLVITEQYGADALRFTLAALTAQGRD-------IKLAKERIEGYRAFANK 591
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 693 VIESGKRADLSTE-------------LKQIDHWILSRIQNYIRDTNAALYSIQTREAIQNSF-FLLQNDVKWY------- 751
Cdd:PRK14900 592 LWNASRFALMNLSgyqergedparlaRTPADRWILARLQRAVNETVEALEAFRFNDAANAVYaFVWHELCDWYielakea 671
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 752 -------QRRGGETLLYYVLDNWVRLMSPFTPHLCEEIWE-------AMGHKDPISLAQYPlyNEDLIDDGAELAEEMIK 817
Cdd:PRK14900 672 lasedpeARRSVQAVLVHCLQTSYRLLHPFMPFITEELWHvlraqvgASAWADSVLAAEYP--RKGEADEAAEAAFRPVL 749
|
....*....
gi 805387474 818 GTLEDVEEI 826
Cdd:PRK14900 750 GIIDAVRNI 758
|
|
| PLN02563 |
PLN02563 |
aminoacyl-tRNA ligase |
5-807 |
6.46e-41 |
|
aminoacyl-tRNA ligase
Pssm-ID: 178177 [Multi-domain] Cd Length: 963 Bit Score: 163.07 E-value: 6.46e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 5 YKPHEIEKKWQKKWNESQIFQAePDKRE----KFFITIPYPYLNG-NLHAGHTRTFTIGDVVARHKRMLGYNVLYPMGFH 79
Cdd:PLN02563 80 YPFHEIEPKWQRYWEENRTFRT-PDDVDtskpKFYVLDMFPYPSGaGLHVGHPEGYTATDILARYKRMQGYNVLHPMGWD 158
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 80 VTGTPivglAELIAnrdpqtmdvyerlhgIPGDILPTlDTPEKIVDYFKREsekaMRNIGYSIDWRRKFTTTDPTYKKFI 159
Cdd:PLN02563 159 AFGLP----AEQYA---------------IETGTHPK-ITTLKNIARFRSQ----LKSLGFSYDWDREISTTEPEYYKWT 214
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 160 EWQYIRLEEKGLIVKGSHPVKWCP-------ND----------NNPV--------------------EDHDILHGEEATI 202
Cdd:PLN02563 215 QWIFLQLLKRGLAYQAEVPVNWCPalgtvlaNEevvdglsergGHPVirkpmrqwmlkitayadrllEDLDDLDWPESIK 294
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 203 V---------EYTLIKF-------RYKDLVLPCATLRPETTYGVTNLWVNPDVTYVKAKVTQGENEEFwvvskEAFRKLT 266
Cdd:PLN02563 295 EmqrnwigrsEGAELDFsvldgegKERDEKITVYTTRPDTLFGATYLVVAPEHPLLSSLTTAEQKEAV-----EEYVDAA 369
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 267 FTDRTVEYIEDVPAKSII--GIKLTNPVTGDEIISLPASFVRPENGSGIVMSVPAHAPFDYlalrdlydadlsEYGITED 344
Cdd:PLN02563 370 SRKSDLERTELQKEKTGVftGSYAINPATGEAIPIWVADYVLGSYGTGAIMAVPAHDTRDF------------EFAQKFD 437
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 345 LRNIKLISlikvPEFGEFPAKE--------IVES----MGITSQKDPKAeeATKIVYRREFHGGVLKELTGKYegqavsk 412
Cdd:PLN02563 438 LPIKWVVK----PADGNEDDAEkaytgegvIVNSsssgLDINGLSSKEA--AKKVIEWLEETGNGKKKVNYKL------- 504
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 413 ikdiltRDFISSNA---GETFyefsePVVCRCGTPCVVNMVKGQwfLNYSNPEwkakvykcLDEMRI--IPEEyrvEFEN 487
Cdd:PLN02563 505 ------RDWLFARQrywGEPI-----PVVFLEDSGEPVPVPESD--LPLTLPE--------LDDFTPtgTGEP---PLAK 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 488 KVDWLKdkacarrkglgTRLPFDKEWLIEslgdSTIYMS-------YYViaRFIENgelkienltlsffdyvllgKSDLA 560
Cdd:PLN02563 561 AVSWVN-----------TVDPSSGKPARR----ETNTMPqwagscwYYL--RFMDP-------------------KNSNA 604
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 561 AASADtglspelLEEirrhfnYWYPVDLRSSGKDLVPNHLLFFLFHHVALFE---------------------------- 612
Cdd:PLN02563 605 LVDKE-------KEK------YWMPVDLYVGGAEHAVLHLLYARFWHKVLYDigvvstkepfqclvnqgmilgeveytaf 671
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 613 ---EEKWPKALAVNG-----------------------------FVSLEGQKMSKSKGPILTMESAVSKYGADITRMYIL 660
Cdd:PLN02563 672 kdsDGEYVSADTADRlgelqqekipeekviksgdsfvlkddpsiRLIARAHKMSKSRGNVVNPDDVVSEYGADSLRLYEM 751
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 661 STAEQTQDADWQRTGIESARRQVDRFYS-FANSVIESGKRADLST--------ELKQIDHWILSRIQNYIRDTnaalySI 731
Cdd:PLN02563 752 FMGPLRDSKTWSTSGVEGVHRFLGRTWRlVVGAPLPDGSFRDGTVvtdeepslEQLRLLHKCIAKVTEEIEST-----RF 826
|
890 900 910 920 930 940 950
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 805387474 732 QTreAIQNSFFLLQNDVKWyqrrggETLLYYVLDNWVRLMSPFTPHLCEEIWEAMGHKDPISLAQYPLYNEDLIDD 807
Cdd:PLN02563 827 NT--AISAMMEFTNAAYKW------DKVPREAIEPFVLLLSPYAPHLAEELWFRLGHSNSLAYEPWPEANPSYLVD 894
|
|
| Ile_Leu_Val_MetRS_core |
cd00668 |
catalytic core domain of isoleucyl, leucyl, valyl and methioninyl tRNA synthetases; Catalytic ... |
452-671 |
2.59e-39 |
|
catalytic core domain of isoleucyl, leucyl, valyl and methioninyl tRNA synthetases; Catalytic core domain of isoleucyl, leucyl, valyl and methioninyl tRNA synthetases. These class I enzymes are all monomers. However, in some species, MetRS functions as a homodimer, as a result of an additional C-terminal domain. These enzymes aminoacylate the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. Enzymes in this subfamily share an insertion in the core domain, which is subject to both deletions and rearrangements. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids. MetRS has a significantly shorter insertion, which lacks the editing function.
Pssm-ID: 185674 [Multi-domain] Cd Length: 312 Bit Score: 148.34 E-value: 2.59e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 452 GQWFLnySNPEWKAKVYKCLDEMRIIPEEYRVEFENKVDWLKDKACARRKGLGTRLPfdkEWLIESLGDSTIYMSYYVIA 531
Cdd:cd00668 140 EQWFF--DMPKFKEKLLKALRRGKIVPEHVKNRMEAWLESLLDWAISRQRYWGTPLP---EDVFDVWFDSGIGPLGSLGY 214
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 532 RFIEngelkienltlsffdyvllgksdlaaasadtglspelleeirRHFNYWYPVDLRSSGKDLVPNHLLFFLFHHVALF 611
Cdd:cd00668 215 PEEK------------------------------------------EWFKDSYPADWHLIGKDILRGWANFWITMLVALF 252
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 805387474 612 EEeKWPKALAVNGFVSLE-GQKMSKSKGPILTMESAVSKYGADITRMYILSTAEQTQDADW 671
Cdd:cd00668 253 GE-IPPKNLLVHGFVLDEgGQKMSKSKGNVIDPSDVVEKYGADALRYYLTSLAPYGDDIRL 312
|
|
| Ile_Leu_Val_MetRS_core |
cd00668 |
catalytic core domain of isoleucyl, leucyl, valyl and methioninyl tRNA synthetases; Catalytic ... |
33-179 |
6.48e-39 |
|
catalytic core domain of isoleucyl, leucyl, valyl and methioninyl tRNA synthetases; Catalytic core domain of isoleucyl, leucyl, valyl and methioninyl tRNA synthetases. These class I enzymes are all monomers. However, in some species, MetRS functions as a homodimer, as a result of an additional C-terminal domain. These enzymes aminoacylate the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. Enzymes in this subfamily share an insertion in the core domain, which is subject to both deletions and rearrangements. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids. MetRS has a significantly shorter insertion, which lacks the editing function.
Pssm-ID: 185674 [Multi-domain] Cd Length: 312 Bit Score: 147.18 E-value: 6.48e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 33 KFFITIPYPYLNGNLHAGHTRTFTIGDVVARHKRMLGYNVLYPMGFHVTGTPIVGLAELIANRDPQTMdvyerlhgipgD 112
Cdd:cd00668 1 KFYVTTPPPYANGSLHLGHALTHIIADFIARYKRMRGYEVPFLPGWDTHGLPIELKAERKGGRKKKTI-----------W 69
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 805387474 113 ILPTLDTPEKIVDYFKRESEKAMRNIGYSIDWRRKFTTTDPTYKKFIEWQYIRLEEKGLIVKGSHPV 179
Cdd:cd00668 70 IEEFREDPKEFVEEMSGEHKEDFRRLGISYDWSDEYITTEPEYSKAVELIFSRLYEKGLIYRGTHPV 136
|
|
| Anticodon_Ia_Leu_AEc |
cd07959 |
Anticodon-binding domain of archaeal and eukaryotic cytoplasmic leucyl tRNA synthetases; This ... |
671-786 |
1.08e-37 |
|
Anticodon-binding domain of archaeal and eukaryotic cytoplasmic leucyl tRNA synthetases; This domain is found in leucyl tRNA synthetases (LeuRS), which belong to the class Ia aminoacyl tRNA synthetases. It lies C-terminal to the catalytic core domain. In contrast to other class Ia enzymes, the anticodon is not used as an identity element in LeuRS (with exceptions such as Saccharomyces cerevisiae and some other eukaryotes). No anticodon-binding site can be defined for this family, which includes archaeal and eukaryotic cytoplasmic members. LeuRS catalyzes the transfer of leucine to the 3'-end of its tRNA.
Pssm-ID: 153413 [Multi-domain] Cd Length: 117 Bit Score: 136.95 E-value: 1.08e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 671 WQRTGIESARRQVDRFYSFANSVIESGKRadlSTELKQIDHWILSRIQNYIRDTNAALYSIQTREAIQNSFFLLQNDVKW 750
Cdd:cd07959 1 FREEEANSAILRLERFYELAEELIETEGE---LEELTFIDRWLLSRLNRLIKETTEAYENMQFREALKEGLYELQNDLDW 77
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 805387474 751 YQRRGGET----LLYYVLDNWVRLMSPFTPHLCEEIWEAM 786
Cdd:cd07959 78 YRERGGAGmnkdLLRRFIEVWTRLLAPFAPHLAEEIWHEL 117
|
|
| ValS |
COG0525 |
Valyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Valyl-tRNA synthetase ... |
1-928 |
8.34e-37 |
|
Valyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Valyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 440291 [Multi-domain] Cd Length: 877 Bit Score: 149.82 E-value: 8.34e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 1 MEQDYKPHEIEKKWQKKWNESQIFQAEPDK-REKFFITIPYPYLNGNLHAGHTRTFTIGDVVARHKRMLGYNVLYpmgfh 79
Cdd:COG0525 3 LPKTYDPKEVEAKWYQYWEENGYFKADPDSdKEPFTIVIPPPNVTGSLHMGHALNNTLQDILIRYKRMQGYNTLW----- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 80 VTGTPIVGlaelIAnrdpqTMDVYERL--------HgipgDIlptldTPEKIVDY---FKRESEKA----MRNIGYSIDW 144
Cdd:COG0525 78 QPGTDHAG----IA-----TQAVVERQlaeegksrH----DL-----GREKFLERvweWKEESGGTitnqLRRLGASCDW 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 145 RR-KFtTTDPTYKK-----FiewqyIRLEEKGLIVKGSHPVKWCPNDNNPVEDhdilhgEEatiVEYTLIK-----FRYK 213
Cdd:COG0525 140 SReRF-TMDEGLSKavrevF-----VRLYEKGLIYRGKRLVNWDPKLKTALSD------LE---VEHEEVKghlwhIRYP 204
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 214 dLV-----LPCATLRPETTYGVTNLWVNPDvtyvkakvtqgeneefwvvskeafrkltftD-RtveYiedvpaKSIIGIK 287
Cdd:COG0525 205 -LAdgsgyIVVATTRPETMLGDTAVAVHPE------------------------------DeR---Y------KHLIGKT 244
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 288 LTNPVTGDEIislP--A-SFVRPENGSGIVMSVPAHAPFDY-LALRdlydadlseygitedlRNIKLISLI----KVPEF 359
Cdd:COG0525 245 VILPLVGREI---PiiAdEYVDPEFGTGAVKITPAHDPNDFeVGKR----------------HNLPMINILdedgTINEN 305
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 360 GE-------FPA-KEIVESMgitsqkdpkaEEAtkivyrrefhgGVLKeltgkyegqavsKIKDiltrdfISSNAGetfy 431
Cdd:COG0525 306 AGkyrgldrFEArKAIVADL----------EEL-----------GLLV------------KVEP------HKHSVG---- 342
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 432 eFSEpvvcRCGTpcVVN-MVKGQWFLNYsnPEWKAKVYKCL--DEMRIIPEEYrvefeNKV--DWLKDKacarrkglgtr 506
Cdd:COG0525 343 -HSD----RSGT--VIEpYLSDQWFVKM--KPLAKPAIEAVedGEIKFVPERW-----EKTyfHWMENI----------- 397
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 507 lpfdKEWLIeslgdstiymS-----------YYViarfiENGELkienltlsffdYVllGKSDLAAASA----------- 564
Cdd:COG0525 398 ----RDWCI----------SrqlwwghripaWYC-----PDGEV-----------YV--ARTEPEACAKagsvnltqded 445
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 565 --DTGLS-----------PELLEEirrhFNYWYPVDLRSSGKDlvpnhLLFF---------L-------FHHV---ALFE 612
Cdd:COG0525 446 vlDTWFSsalwpfstlgwPEKTED----LKYFYPTSVLVTGFD-----IIFFwvarmimmgLhftgevpFKDVyihGLVR 516
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 613 EEKwpkalavngfvsleGQKMSKSKG----PILTMEsavsKYGADITRMYILSTAEQTQDA--DWQRtgIESARrqvdrf 686
Cdd:COG0525 517 DEQ--------------GRKMSKSKGnvidPLDLID----KYGADALRFTLAALASPGRDIkfDEER--VEGYR------ 570
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 687 ySFAN------------SVIESGKRADLSTELKQIDHWILSRIQNYIRDTNAAL--YSIQtrEAIQ-------NSF---F 742
Cdd:COG0525 571 -NFANklwnasrfvlmnLEGFDPGLDPDPEELSLADRWILSRLNKTIAEVTEALekYRFD--EAAQalydfvwNEFcdwY 647
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 743 L------LQNDVKwYQRRGGETLLYYVLDNWVRLMSPFTPHLCEEIWEAMG---HKDPISLAQYPLYNEDLIDDGAELAE 813
Cdd:COG0525 648 LelakprLYGGDE-AAKRETRATLVYVLEQILRLLHPFMPFITEEIWQKLPprkEGESIMLAPWPEADEELIDEEAEAEF 726
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 814 EMIKGTledVEEI--IRVTKMTP--QKVHLYtapawkaeaIRCACEMQLECSLEVGTLIKKLmANPD-LKRFGKEIPKF- 887
Cdd:COG0525 727 EWLKEV---ISAIrnIRAEMNIPpsKKLPLL---------LKGADEADRARLEENAAYIKRL-ARLEeITILVDEKPEGa 793
|
1050 1060 1070 1080
....*....|....*....|....*....|....*....|....
gi 805387474 888 VQKIVPEFKsgsadrYEILTGPNID---EQTLLKESISFLEKEI 928
Cdd:COG0525 794 ASAVVGGAE------VFLPLEGLIDveaERARLEKELAKLEKEI 831
|
|
| PTZ00419 |
PTZ00419 |
valyl-tRNA synthetase-like protein; Provisional |
1-839 |
1.85e-32 |
|
valyl-tRNA synthetase-like protein; Provisional
Pssm-ID: 240411 [Multi-domain] Cd Length: 995 Bit Score: 136.29 E-value: 1.85e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 1 MEQDYKPHEIEKKWQKKWNESQIFQAEPD-----KREKFFITIPYPYLNGNLHAGHTRTFTIGDVVARHKRMLGYNVLYp 75
Cdd:PTZ00419 24 MAASYDPKEVESGWYEWWEKSGFFKPAEDakslnSGKKFVIVLPPPNVTGYLHIGHALTGAIQDSLIRYHRMKGDETLW- 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 76 mgfhVTGTPIVGLAelianrdpqTMDVYER-LHGIPGDILPTL---DTPEKIVDYFKRESEK---AMRNIGYSIDWRRKF 148
Cdd:PTZ00419 103 ----VPGTDHAGIA---------TQVVVEKkLMKEENKTRHDLgreEFLKKVWEWKDKHGNNicnQLRRLGSSLDWSREV 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 149 TTTDPTYKKFIEWQYIRLEEKGLIVKGSHPVKWCPNDNNPVEDHDILHGE-----EATI------VEY-TLIKFRYK--- 213
Cdd:PTZ00419 170 FTMDEQRSKAVKEAFVRLYEDGLIYRDTRLVNWCCYLKTAISDIEVEFEEiekptKITIpgydkkVEVgVLWHFAYPled 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 214 --DLVLPCATLRPETTYGVTNLWVNPDvtyvkakvtqgeneefwvvskeafrkltftdrtveyieDVPAKSIIGIKLTNP 291
Cdd:PTZ00419 250 sgQEEIVVATTRIETMLGDVAVAVHPK--------------------------------------DERYKKLHGKELIHP 291
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 292 VTGDEIISLPA--SFVRPENGSGIVMSVPAHAPFDY-LALRdlydadlseygitedlRNIKLISLI----KV-PEFGEFP 363
Cdd:PTZ00419 292 FIPDRKIPIIAddELVDMEFGTGAVKITPAHDPNDYeIAKR----------------HNLPFINIFtldgKInENGGEFA 355
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 364 A-------KEIVE---SMGITSQKDPKAeeatkivYRREFhggvlkeltgkyegqaVSKIKDILtrdfissnagetfyef 433
Cdd:PTZ00419 356 GmhrfdcrRKIEEelkEMGLLRDKVPNP-------MRLPR----------------CSRSGDIV---------------- 396
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 434 sEPvvcrcgtpcvvnMVKGQWFLNYSnpEWKAKVYKCLD--EMRIIPEEYRVEF----ENKVDWlkdkaCARRKgL--GT 505
Cdd:PTZ00419 397 -EP------------MLIPQWYVNCK--DMAKRAVEAVRngELKIIPSSHENVWyhwlENIQDW-----CISRQ-LwwGH 455
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 506 RLPfdkEWLIESLGDSTIY--MSYYVIARFIENGELK-IENLTLSFFDYVLLGKSDLaaasADTGLS-----------PE 571
Cdd:PTZ00419 456 RIP---AYRVISKGPETDPsdEEPWVVARSEEEALEKaKKKFGLSEEDFELEQDEDV----LDTWFSsglfpfstlgwPD 528
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 572 LLEEIRRHFnywyPVDLRSSGKDlvpnhLLFFLfhhVA------LFEEEKWP-KALAVNGFV-SLEGQKMSKSKGPIL-- 641
Cdd:PTZ00419 529 QTDDLQRFF----PTSLLETGSD-----ILFFW---VArmvmmsLHLTDKLPfKTVFLHAMVrDSQGEKMSKSKGNVIdp 596
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 642 ----------TMESAVSKY-------------------------GADITRMYILSTAEQTQDA--DWQRTgieSARRQ-- 682
Cdd:PTZ00419 597 leviegislqDLNQKLYEGnlpekeikraielqkkefpngipecGTDALRFGLLAYTQQGRNInlDINRV---VGYRHfc 673
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 683 ----------VDRFYSFANSVIESGKRADLSTELKQIDHWILSRIQNYIRDTNAALYSIQTREAIQN--SFFL------- 743
Cdd:PTZ00419 674 nklwnavkfaLMKLLKDFNLPNSTLFKPNNVESLPWEDKWILHRLNVAIKEVTEGFKEYDFSEATQAtyNFWLyelcdvy 753
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 744 -------LQNDVKWYQRRGGETLLYYVLDNWVRLMSPFTPHLCEEIWeamgHKDP--------ISLAQYPLYNEDLIDdg 808
Cdd:PTZ00419 754 lelikprLSKQSDGERKQHAQDVLHTVLDIGLRLLHPMMPFITEELY----QRLPnylrksesISIAKYPQPNPGWNN-- 827
|
970 980 990
....*....|....*....|....*....|....
gi 805387474 809 AELAEEMIKgtLEDVEEIIRVTKMT---PQKVHL 839
Cdd:PTZ00419 828 EALDEEMKI--IMSIVKSIRSLIATlgiPNKTKP 859
|
|
| ValRS_core |
cd00817 |
catalytic core domain of valyl-tRNA synthetases; Valine amino-acyl tRNA synthetase (ValRS) ... |
32-194 |
4.12e-28 |
|
catalytic core domain of valyl-tRNA synthetases; Valine amino-acyl tRNA synthetase (ValRS) catalytic core domain. This enzyme is a monomer which aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. ValRS has an insertion in the core domain, which is subject to both deletions and rearrangements. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids.
Pssm-ID: 185677 [Multi-domain] Cd Length: 382 Bit Score: 117.35 E-value: 4.12e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 32 EKFFITIPYPYLNGNLHAGHTRTFTIGDVVARHKRMLGYNVLYPMGFHVTGTPivglaelianrdpqTMDVYERLHGIPG 111
Cdd:cd00817 1 PVFVIDTPPPNVTGSLHMGHALNNTIQDIIARYKRMKGYNVLWPPGTDHAGIA--------------TQVVVEKKLGIEG 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 112 DILPTLDTPE--KIVDYFKRESEKAMRN----IGYSIDWRRKFTTTDPTYKKFIEWQYIRLEEKGLIVKGSHPVKWCPND 185
Cdd:cd00817 67 KTRHDLGREEflEKCWEWKEESGGKIREqlkrLGASVDWSREYFTMDPGLSRAVQEAFVRLYEKGLIYRDNRLVNWCPKL 146
|
....*....
gi 805387474 186 NNPVEDHDI 194
Cdd:cd00817 147 RTAISDIEV 155
|
|
| PLN02943 |
PLN02943 |
aminoacyl-tRNA ligase |
17-789 |
1.27e-26 |
|
aminoacyl-tRNA ligase
Pssm-ID: 215509 [Multi-domain] Cd Length: 958 Bit Score: 117.35 E-value: 1.27e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 17 KWNESQ-IFQAEPDK-REKFFITIPYPYLNGNLHAGHTRTFTIGDVVARHKRMLGYNVLYpmgfhVTGTPIVGLAelian 94
Cdd:PLN02943 71 NWWESQgYFKPNFDRgGDPFVIPMPPPNVTGSLHMGHAMFVTLEDIMVRYNRMKGRPTLW-----IPGTDHAGIA----- 140
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 95 rdpqTMDVYERLHGIPGdILPTLDTPEKIVDYFKRESEK-------AMRNIGYSIDWRRKFTTTDPTYKKFIEWQYIRLE 167
Cdd:PLN02943 141 ----TQLVVEKMLASEG-IKRTDLGRDEFTKRVWEWKEKyggtitnQIKRLGASCDWSRERFTLDEQLSRAVVEAFVRLH 215
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 168 EKGLIVKGSHPVKWCPNDNNPVEDHDILHGEEATIVEYtlIKFRY---KDLVLPCATLRPETTYGVTNLWVNP-DVTYVK 243
Cdd:PLN02943 216 EKGLIYQGSYMVNWSPNLQTAVSDLEVEYSEEPGTLYY--IKYRVaggSEDFLTIATTRPETLFGDVAIAVNPeDDRYSK 293
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 244 akvtqgeneefwVVSKEAFRKLTFtDRTVeyiedvpaksiigikltnPVTGDEiislpasFVRPENGSGIVMSVPAHAPF 323
Cdd:PLN02943 294 ------------YIGKMAIVPMTY-GRHV------------------PIIADR-------YVDKDFGTGVLKISPGHDHN 335
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 324 DYLALRDLydadlseygitedlrniklisliKVPefgefpakeIVESMgitsQKDpkaeeatkivyrrefhgGVLKELTG 403
Cdd:PLN02943 336 DYLLARKL-----------------------GLP---------ILNVM----NKD-----------------GTLNEVAG 362
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 404 KYEGQAVSKIKDILTRDFISSNAgetfyefsEPVVCRC-----GTPCVVNMVKGQWFLNYSNPEWKAKVYKCLDEMRIIP 478
Cdd:PLN02943 363 LYWFEAREKLWSDLEETGLAVKK--------EPHTLRVprsqrGGEVIEPLVSKQWFVTMEPLAEKALKAVENGELTIIP 434
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 479 EEYRVEFENKVDWLKDKACARRKGLGTRLPFdkeWLIESLGDStiymSYYVIAR------------FIENGELKIENLTL 546
Cdd:PLN02943 435 ERFEKIYNHWLSNIKDWCISRQLWWGHRIPV---WYIVGKDCE----EDYIVARsaeealekarekYGKDVEIYQDPDVL 507
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 547 ------SFFDYVLLGKSDLAAasadtglspelleeirRHFNYWYPVDLRSSGKDlvpnhLLFFLFHHVALFEEE---KWP 617
Cdd:PLN02943 508 dtwfssALWPFSTLGWPDVSA----------------EDFKKFYPTTVLETGHD-----ILFFWVARMVMMGIEftgTVP 566
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 618 -KALAVNGFV-SLEGQKMSKSKGPILTMESAVSKYGADITRmYILSTAEQTQDADWQRTGIESARrqvdrfySFANSVIE 695
Cdd:PLN02943 567 fSYVYLHGLIrDSQGRKMSKTLGNVIDPLDTIKEFGTDALR-FTLALGTAGQDLNLSTERLTSNK-------AFTNKLWN 638
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 696 SGK--------RADLSTELKQIDH----------------WILSRIQNYIRDTNAALYSIQTREAIQNSF-FLLQNDVKW 750
Cdd:PLN02943 639 AGKfvlqnlpsQSDTSAWEHILACkfdkeesllslplpecWVVSKLHELIDSVTTSYDKYFFGDVGREIYdFFWSDFADW 718
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|....
gi 805387474 751 Y--------QRRGGET-------LLYYVLDNWVRLMSPFTPHLCEEIWEAMGHK 789
Cdd:PLN02943 719 YieasktrlYHSGDNSalsraqaVLLYVFENILKLLHPFMPFVTEELWQALPYR 772
|
|
| Anticodon_Ia_Ile_ABEc |
cd07961 |
Anticodon-binding domain of archaeal, bacterial, and eukaryotic cytoplasmic isoleucyl tRNA ... |
694-827 |
7.67e-21 |
|
Anticodon-binding domain of archaeal, bacterial, and eukaryotic cytoplasmic isoleucyl tRNA synthetases; This domain is found in isoleucyl tRNA synthetases (IleRS), which belong to the class Ia aminoacyl tRNA synthetases. It lies C-terminal to the catalytic core domain, and recognizes and specifically binds to the tRNA anticodon. This family includes bacterial, archaeal, and eukaryotic cytoplasmic members. IleRS catalyzes the transfer of isoleucine to the 3'-end of its tRNA.
Pssm-ID: 153415 [Multi-domain] Cd Length: 183 Bit Score: 91.07 E-value: 7.67e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 694 IESGKRADLSTELKQIDHWILSRIQNYIRDTNAAL--YSIQT--REAIqnSFFLlqNDVKWYQRR------GGETL---- 759
Cdd:cd07961 33 FDPGKDDDAVASLNVLDRWILSRLNSLIKEVTEEMeaYDLYTavRALL--EFID--ELTNWYIRRnrkrfwGEEGDddkl 108
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 805387474 760 -----LYYVLDNWVRLMSPFTPHLCEEIWEAMGHKDP-----ISLAQYPLYNEDLIDdgAELAEEMikgtlEDVEEII 827
Cdd:cd07961 109 aayatLYEVLLTLSRLMAPFTPFITEEIYQNLRRELGdapesVHLLDWPEVDESLID--EELEEAM-----ELVREIV 179
|
|
| PLN02381 |
PLN02381 |
valyl-tRNA synthetase |
1-821 |
2.13e-19 |
|
valyl-tRNA synthetase
Pssm-ID: 215214 [Multi-domain] Cd Length: 1066 Bit Score: 94.20 E-value: 2.13e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 1 MEQDYKPHEIEKKWQKKWNESQIFQAEPDK-REKFFITIPYPYLNGNLHAGHTRTFTIGDVVARHKRMLGYNVLYPMGFH 79
Cdd:PLN02381 96 MAKQYSPSAVEKSWYAWWEKSGYFGADAKSsKPPFVIVLPPPNVTGALHIGHALTAAIEDTIIRWKRMSGYNALWVPGVD 175
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 80 VTG--TPIVGLAELIANRDPQTMD---------VYERLHGIPGDILptldtpekivdyfkreseKAMRNIGYSIDWRRK- 147
Cdd:PLN02381 176 HAGiaTQVVVEKKLMRERHLTRHDigreefvseVWKWKDEYGGTIL------------------NQLRRLGASLDWSREc 237
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 148 FTTTDPTYKKFIEwQYIRLEEKGLIVKGSHPVKWCPNDNNPVEDHDILHGE--EATI---------VEY-TLIKFRYK-- 213
Cdd:PLN02381 238 FTMDEQRSKAVTE-AFVRLYKEGLIYRDIRLVNWDCTLRTAISDVEVDYIDikERTLlkvpgydkpVEFgVLTSFAYPle 316
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 214 ----DLVLpcATLRPETTYGVTNLWVNPDvtyvkakvtqgeneefwvvskeafrkltftdrtveyieDVPAKSIIGIKLT 289
Cdd:PLN02381 317 gglgEIVV--ATTRIETMLGDTAIAIHPD--------------------------------------DERYKHLHGKFAV 356
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 290 NPVTGDEI-ISLPASFVRPENGSGIVMSVPAHAPFDYlalrdlydadlsEYGITEDLRNIKL------ISLIKVPEFGEF 362
Cdd:PLN02381 357 HPFNGRKLpIICDAILVDPNFGTGAVKITPAHDPNDF------------EVGKRHNLEFINIftddgkINSNGGSEFAGM 424
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 363 PAKEIVESMGITSQKDPKAEEATKivyrREFHGGVlkeltgkyegqaVSKIKDILtrdfissnagetfyefsEPvvcrcg 442
Cdd:PLN02381 425 PRFAAREAVIEALQKKGLYRGAKN----NEMRLGL------------CSRTNDVV-----------------EP------ 465
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 443 tpcvvnMVKGQWFLNYSNPEWKAKVYKCLDE---MRIIPEEYRVEFENKVDWLKDKACARRKGLGTRLPfdkEWLI---- 515
Cdd:PLN02381 466 ------MIKPQWFVNCSSMAKQALDAAIDGEnkkLEFIPKQYLAEWKRWLENIRDWCISRQLWWGHRIP---AWYVtled 536
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 516 ESLGDSTIYMSYYVIARfieNGELKIENLTLSFF--DYVLLGKSDLAAASADTGLSPELL---EEIRRHFNYWYPVDLRS 590
Cdd:PLN02381 537 DQLKELGSYNDHWVVAR---NESDALLEASQKFPgkKFELSQDPDVLDTWFSSGLFPLSVlgwPDDTDDLKAFYPTSVLE 613
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 591 SGKDLvpnhLLFFLFHHVAL---------FEE------------EKWPKALA--------VNGfVSLEGQKMSKSKGPIL 641
Cdd:PLN02381 614 TGHDI----LFFWVARMVMMgmqlggdvpFRKvylhpmirdahgRKMSKSLGnvidplevING-ISLEGLHKRLEEGNLD 688
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 642 TMESAVSKY-------------GADITRMYILSTAEQTQ--DADWQRtgIESARRQVDRFYS---FANSVIESG--KRAD 701
Cdd:PLN02381 689 PKELVVAKEgqkkdfpngiaecGTDALRFALVSYTAQSDkiNLDILR--VVGYRQWCNKLWNavrFAMSKLGDDytPPAT 766
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 702 LSTE-LKQIDHWILSRIQNYIRDTNAALYSIQTR-------------------EAIQNSFFllqNDVKWY--QRRGGETL 759
Cdd:PLN02381 767 LSVEtMPFSCKWILSVLNKAISKTVSSLDAYEFSdaastvyswwqyqfcdvfiEAIKPYFA---GDNPEFasERAAAQDT 843
|
890 900 910 920 930 940
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 805387474 760 LYYVLDNWVRLMSPFTPHLCEEIWE----AMGH--KDPISLAQYPLYNEDLIDDGAELAEEMIKGTLE 821
Cdd:PLN02381 844 LWICLDTGLRLLHPFMPFVTEELWQrlpqPKDHtrKDSIMISEYPSAVEAWTNEKVEYEMDLVLSTVK 911
|
|
| Anticodon_1 |
pfam08264 |
Anticodon-binding domain of tRNA ligase; This domain is found mainly hydrophobic tRNA ... |
710-839 |
2.01e-18 |
|
Anticodon-binding domain of tRNA ligase; This domain is found mainly hydrophobic tRNA synthetases. The domain binds to the anticodon of the tRNA ligase.
Pssm-ID: 400523 [Multi-domain] Cd Length: 141 Bit Score: 82.84 E-value: 2.01e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 710 DHWILSRIQNYIRDTNAALYSIQTREAIQNSFFLLQNDV-KWYQRR------------GGETLLYYVLDNWVRLMSPFTP 776
Cdd:pfam08264 1 DRWILSRLNKLIKEVTEAYENYRFNTAAQALYEFFWNDLsDWYLELikdrlygeepdsRAQTTLYEVLETLLRLLAPFMP 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 805387474 777 HLCEEIWeamgHKDPISLAQYPlynEDLIDDGAELAEEM-----IKGTLEDVEEIIRVTKMTPQKVHL 839
Cdd:pfam08264 81 FITEELW----QKESIHLAPWP---EDAELEEAELEEAFelrqeIVQAIRKLRSELKIKKSLPLEVVI 141
|
|
| tRNA-synt_1g |
pfam09334 |
tRNA synthetases class I (M); This family includes methionyl tRNA synthetases. |
34-186 |
1.65e-16 |
|
tRNA synthetases class I (M); This family includes methionyl tRNA synthetases.
Pssm-ID: 401322 [Multi-domain] Cd Length: 387 Bit Score: 82.72 E-value: 1.65e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 34 FFITIPYPYLNGNLHAGHTRTFTIGDVVARHKRMLGYNVLYPMGFHVTGTPIVGLAElianrdpqtmdvyerLHGIpgdi 113
Cdd:pfam09334 1 ILVTTALPYANGPPHLGHLYSYIPADIFARYLRLRGYDVLFVCGTDEHGTPIELKAE---------------KEGI---- 61
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 805387474 114 lptldTPEKIVDYFKRESEKAMRNIGYSIDwrrKFT-TTDPTYKKFIEWQYIRLEEKGLIVKGSHPVKWCPNDN 186
Cdd:pfam09334 62 -----TPEELVDRYHEIHREDFKKFNISFD---DYGrTTSERHHELVQEFFLKLYENGYIYEKEIEQFYCPSDE 127
|
|
| PLN02843 |
PLN02843 |
isoleucyl-tRNA synthetase |
11-795 |
1.28e-15 |
|
isoleucyl-tRNA synthetase
Pssm-ID: 215452 [Multi-domain] Cd Length: 974 Bit Score: 81.74 E-value: 1.28e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 11 EKKWQKKWNESQIFQAEPDKR--EKFFITIPYPYLNGNLHAGHTRTFTIGDVVARHKRMLGYNVLYPMGFHVTGTPIvgl 88
Cdd:PLN02843 9 EPEIQKLWEENQVYKRVSDRNngESFTLHDGPPYANGDLHIGHALNKILKDFINRYQLLQGKKVHYVPGWDCHGLPI--- 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 89 aELianRDPQTMDVYERlhgipgDILPTLDTPEKIVDYFKRESEKAM---RNIGYSIDWRRKFTTTDPTYkkfiEWQYIR 165
Cdd:PLN02843 86 -EL---KVLQSLDQEAR------KELTPIKLRAKAAKFAKKTVDTQResfKRYGVWGDWENPYLTLDPEY----EAAQIE 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 166 ----LEEKGLIVKGSHPVKWCPNDNNPVEDHDILHGE--------------EATIVEYTLIKFRYKDLVLPCATLRPETT 227
Cdd:PLN02843 152 vfgqMFLNGYIYRGRKPVHWSPSSRTALAEAELEYPEghvsksiyvafpvvSPSETSPEELEEFLPGLSLAIWTTTPWTM 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 228 YGVTNLWVNPDVTYVKAKVTQGENEE---------------------FWVVSKEAFRKL-TFTDRTVEYIEDVPAKSIIG 285
Cdd:PLN02843 232 PANAAVAVNDKLQYSVVEVQSFSEDEstsggnkkkrpgnvlkeqqklFLIVATDLVPALeAKWGVKLVVLKTFPGSDLEG 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 286 IKLTNPVTGDE-IISLPASFVRPENGSGIVMSVPAHAPFDYL-ALRdlydadlseYGitedlrnIKLISliKVPEFGEFp 363
Cdd:PLN02843 312 CRYIHPLYNREsPVVIGGDYITTESGTGLVHTAPGHGQEDYItGLK---------YG-------LPLLS--PVDDAGKF- 372
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 364 akeivesmgitsqkdpkAEEAtkivyrrefhggvlkeltGKYEGQAVSKIKDILTRDFISSNAG---ETFYEFSEPVVCR 440
Cdd:PLN02843 373 -----------------TEEA------------------GQFSGLSVLGEGNAAVVEALDEAGSllmEEAYGHKYPYDWR 417
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 441 CGTPCVVNMVKgQWFLnySNPEWKAKVYKCLDEMRIIPE--EYRVE--FENKVDWlkdkaC-ARRKGLGTRLP--FDKEW 513
Cdd:PLN02843 418 TKKPTIFRATE-QWFA--SVEGFRQAALDAIDKVKWIPAqgENRIRamVSGRSDW-----CiSRQRTWGVPIPvfYHVET 489
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 514 LIESLGDSTIymsYYVIARFIENG-----ELKIENL-----------------TLS-FFDyvlLGKSDLAAASADTGLSp 570
Cdd:PLN02843 490 KEPLMNEETI---AHVKSIVAQKGsdawwYMDVEDLlpekyrdkasdyekgtdTMDvWFD---SGSSWAGVLGSREGLS- 562
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 571 elleeirrhfnywYPVDLRSSGKDlvpNHLLFF---LFHHVAlfEEEKWP-KALAVNGFVSLE-GQKMSKSKG----PIL 641
Cdd:PLN02843 563 -------------YPADLYLEGSD---QHRGWFqssLLTSVA--TKGKAPyKSVLTHGFVLDEkGFKMSKSLGnvvdPRL 624
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 642 TMESAVSK-----YGADITRMYILSTaEQTQDAdwqRTGIESARRQVD---------RF-------YSFANSViesgKRA 700
Cdd:PLN02843 625 VIEGGKNQkqepaYGADVLRLWVASV-DYTGDV---LIGPQILKQMSDiyrklrgtlRYllgnlhdWKPDNAV----PYE 696
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 701 DLSTelkqIDHWILSRIQNYIRDTNAALYSIQTREAIQ--NSF--FLLQN---DV---KWY-------QRRGGETLLYYV 763
Cdd:PLN02843 697 DLPS----IDKYALFQLENVVNEIEESYDNYQFFKIFQilQRFtiVDLSNfylDVakdRLYvggttsfTRRSCQTVLAAH 772
|
890 900 910
....*....|....*....|....*....|..
gi 805387474 764 LDNWVRLMSPFTPHLCEEIWEAMGHKDPISLA 795
Cdd:PLN02843 773 LLSLLRAIAPILPHLAEDAWQNLPFQEDGSAA 804
|
|
| PRK11893 |
PRK11893 |
methionyl-tRNA synthetase; Reviewed |
428-804 |
3.11e-15 |
|
methionyl-tRNA synthetase; Reviewed
Pssm-ID: 237012 [Multi-domain] Cd Length: 511 Bit Score: 79.54 E-value: 3.11e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 428 ETFYEFSE-----PVVCRCGTPCVVNMVKgQWFLNYSNpeWKAKVYKCLDEM--RIIPEEYRVEFENKVdwlkdkacarR 500
Cdd:PRK11893 129 EEFYTESEliedgYRCPPTGAPVEWVEEE-SYFFRLSK--YQDKLLELYEANpdFIQPASRRNEVISFV----------K 195
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 501 KGLG----TRLPFDkeWLIESLGDS--TIYMsyyviarfiengelkienltlsFFDYvLLGKsdLAAAsadtgLSPELLE 574
Cdd:PRK11893 196 SGLKdlsiSRTNFD--WGIPVPGDPkhVIYV----------------------WFDA-LTNY--LTAL-----GYPDDEE 243
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 575 EIRRHFNYWYPVDLRSSGKDLVpnhllffLFHHV-------ALfeEEKWPKALAVNGFVSLEGQKMSKSKGPILTMESAV 647
Cdd:PRK11893 244 LLAELFNKYWPADVHLIGKDIL-------RFHAVywpaflmAA--GLPLPKRVFAHGFLTLDGEKMSKSLGNVIDPFDLV 314
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 648 SKYGADITRMYILSTAEQTQDADWQRTGIEsARRQVDRFYSFAN--SVIESG----------KRADLSTELKQIDHWILS 715
Cdd:PRK11893 315 DEYGVDAVRYFLLREIPFGQDGDFSREAFI-NRINADLANDLGNlaQRTLSMiaknfdgkvpEPGALTEADEALLEAAAA 393
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 716 RIQNYIRDTNAALYSIQTREAIQ-----NSFFLLQNDVKWY--QRRGGETLLYYVLdNWVR----LMSPFTPHLCEEIWE 784
Cdd:PRK11893 394 LLERVRAAMDNLAFDKALEAILAlvraaNKYIDEQAPWSLAktDPERLATVLYTLL-EVLRgiavLLQPVMPELAAKILD 472
|
410 420
....*....|....*....|
gi 805387474 785 AMGHKDPISLAQYPLYNEDL 804
Cdd:PRK11893 473 QLGVEEDENRDFAALSWGRL 492
|
|
| PRK11893 |
PRK11893 |
methionyl-tRNA synthetase; Reviewed |
32-185 |
4.20e-14 |
|
methionyl-tRNA synthetase; Reviewed
Pssm-ID: 237012 [Multi-domain] Cd Length: 511 Bit Score: 76.07 E-value: 4.20e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 32 EKFFITIPYPYLNGNLHAGHTRTFTIGDVVARHKRMLGYNVLYpmgfhVTGT-----PIVGLAELiANRDPQtmdvyerl 106
Cdd:PRK11893 1 KKFYITTPIYYPNGKPHIGHAYTTLAADVLARFKRLRGYDVFF-----LTGTdehgqKIQRKAEE-AGISPQ-------- 66
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 805387474 107 hgipgdilptlDTPEKIVDYFKReSEKAMrNIGYSiDWRRkftTTDPTYKKFIEWQYIRLEEKGLIVKGSHPVKWCPND 185
Cdd:PRK11893 67 -----------ELADRNSAAFKR-LWEAL-NISYD-DFIR---TTDPRHKEAVQEIFQRLLANGDIYLGKYEGWYCVRC 128
|
|
| MetG |
COG0143 |
Methionyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Methionyl-tRNA ... |
592-787 |
1.39e-13 |
|
Methionyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Methionyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439913 [Multi-domain] Cd Length: 544 Bit Score: 74.38 E-value: 1.39e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 592 GKDLVPNHLLFF---LfhhvaLFEEEKWPKALAVNGFVSLEGQKMSKSKGPILTMESAVSKYGADITRMYILSTAEQTQD 668
Cdd:COG0143 289 GKDIIRFHAIIWpamL-----MAAGLPLPKKVFAHGFLTVEGEKMSKSRGNVIDPDDLLDRYGPDALRYYLLREVPFGQD 363
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 669 ADWqrtgieSARRQVDRFYS--------FANSVIE-SGKRAD----LSTELKQIDHWILSRIQNYIRDTNAALYSIQTRE 735
Cdd:COG0143 364 GDF------SWEDFVARVNSdlandlgnLASRTLSmIHKYFDgkvpEPGELTEADEELLAEAEAALEEVAEAMEAFEFRK 437
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 805387474 736 AIQ---------NSFFllqnDVK--W-----YQRRGGETLLYYVLdNWVR----LMSPFTPHLCEEIWEAMG 787
Cdd:COG0143 438 ALEeimalaraaNKYI----DETapWklakdEDPERLATVLYTLL-EALRilaiLLKPFLPETAEKILEQLG 504
|
|
| ValRS_core |
cd00817 |
catalytic core domain of valyl-tRNA synthetases; Valine amino-acyl tRNA synthetase (ValRS) ... |
438-668 |
1.56e-13 |
|
catalytic core domain of valyl-tRNA synthetases; Valine amino-acyl tRNA synthetase (ValRS) catalytic core domain. This enzyme is a monomer which aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. ValRS has an insertion in the core domain, which is subject to both deletions and rearrangements. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids.
Pssm-ID: 185677 [Multi-domain] Cd Length: 382 Bit Score: 73.43 E-value: 1.56e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 438 VC-RCGTPcVVNMVKGQWFLNYSnpEWKAKVYKCLDE--MRIIPEEYRVEFENKVDWLKDKACARRKGLGTRLPFdkeWL 514
Cdd:cd00817 155 VCsRSGDV-IEPLLKPQWFVKVK--DLAKKALEAVKEgdIKFVPERMEKRYENWLENIRDWCISRQLWWGHRIPA---WY 228
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 515 IESLGdstiymsYYVIARFIENGELKIENLtlsffDYVLLGKSDLAAAS------ADTGLSPELL----EEIRRhFNYWY 584
Cdd:cd00817 229 CKDGG-------HWVVAREEDEAIDKAAPE-----ACVPCGGEELKQDEdvldtwFSSSLWPFSTlgwpEETKD-LKKFY 295
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 585 PVDLRSSGKDLvpnhLLFFLFHHVAL---FEEEKWPKALAVNGFV-SLEGQKMSKSKGPILTMESAVSKYGADITRMYIL 660
Cdd:cd00817 296 PTSLLVTGHDI----IFFWVARMIMRglkLTGKLPFKEVYLHGLVrDEDGRKMSKSLGNVIDPLDVIDGYGADALRFTLA 371
|
....*...
gi 805387474 661 STAEQTQD 668
Cdd:cd00817 372 SAATQGRD 379
|
|
| IleRS_core |
cd00818 |
catalytic core domain of isoleucyl-tRNA synthetases; Isoleucine amino-acyl tRNA synthetases ... |
41-181 |
8.46e-13 |
|
catalytic core domain of isoleucyl-tRNA synthetases; Isoleucine amino-acyl tRNA synthetases (IleRS) catalytic core domain . This class I enzyme is a monomer which aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. IleRS has an insertion in the core domain, which is subject to both deletions and rearrangements. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids.
Pssm-ID: 173909 [Multi-domain] Cd Length: 338 Bit Score: 70.72 E-value: 8.46e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 41 PYLNGNLHAGHTRTFTIGDVVARHKRMLGYNVLYPMGFHVTGTPIvglaELIAnrdpqtmdvyERLHGIPGDILPTLDTP 120
Cdd:cd00818 10 PYANGLPHYGHALNKILKDIINRYKTMQGYYVPRRPGWDCHGLPI----ELKV----------EKELGISGKKDIEKMGI 75
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 805387474 121 E-------KIVDYFKRESEKAMRNIGYSIDWRRKFTTTDPTYKKFIEWQYIRLEEKGLIVKGSHPVKW 181
Cdd:cd00818 76 AefnakcrEFALRYVDEQEEQFQRLGVWVDWENPYKTMDPEYMESVWWVFKQLHEKGLLYRGYKVVPW 143
|
|
| Anticodon_Ia_Ile_BEm |
cd07960 |
Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; ... |
705-815 |
4.59e-11 |
|
Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; This domain is found in isoleucyl tRNA synthetases (IleRS), which belong to the class Ia aminoacyl tRNA synthetases. It lies C-terminal to the catalytic core domain, and recognizes and specifically binds to the tRNA anticodon. This family includes bacterial and eukaryotic mitochondrial members. IleRS catalyzes the transfer of isoleucine to the 3'-end of its tRNA.
Pssm-ID: 153414 [Multi-domain] Cd Length: 180 Bit Score: 62.54 E-value: 4.59e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 705 ELKQIDHWILSRIQNYIRDTNAALYSIQTREAIQ--NSFflLQNDVK-WY----------------QRRGGETLLYYVLD 765
Cdd:cd07960 41 ELLELDRYALHRLNELIKEVREAYENYEFHKVYQalNNF--CTVDLSaFYldiikdrlycdakdslERRSAQTVLYHILD 118
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 805387474 766 NWVRLMSPFTPHLCEEIWEAMGHKDPIS---LAQYPLYNEDLIDDgaELAEEM 815
Cdd:cd07960 119 ALLKLLAPILPFTAEEVWEHLPGEKKEEsvfLEDWPELPEEWKDE--ELEEKW 169
|
|
| CysS |
COG0215 |
Cysteinyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Cysteinyl-tRNA ... |
623-760 |
3.34e-10 |
|
Cysteinyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Cysteinyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439985 [Multi-domain] Cd Length: 465 Bit Score: 63.58 E-value: 3.34e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 623 NGFVSLEGQKMSKSKGPILTMESAVSKYGADITRMYILSTAEQTQdADWQRTGIESARRQVDRFYSFANSVIESGKRADL 702
Cdd:COG0215 256 NGFLTVNGEKMSKSLGNFFTVRDLLKKYDPEVLRFFLLSAHYRSP-LDFSEEALEEAEKALERLYNALRRLEEALGAADS 334
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 703 STElkQIDHWI----------------LSRIQNYIRDTNAALYSIQTREAIQ---------NSFF-LLQNDVKWYQRRGG 756
Cdd:COG0215 335 SAE--EIEELReefiaamdddfntpeaLAVLFELVREINKALDEGEDKAALAalaallralGGVLgLLLLEPEAWQGAAE 412
|
....
gi 805387474 757 ETLL 760
Cdd:COG0215 413 DELL 416
|
|
| PRK12267 |
PRK12267 |
methionyl-tRNA synthetase; Reviewed |
33-175 |
4.63e-10 |
|
methionyl-tRNA synthetase; Reviewed
Pssm-ID: 237028 [Multi-domain] Cd Length: 648 Bit Score: 63.28 E-value: 4.63e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 33 KFFITIPYPYLNGNLHAGHTRTFTIGDVVARHKRMLGYNVlypmgFHVTGT-----PIVGLAELiANRDPQTmdvYerlh 107
Cdd:PRK12267 5 TFYITTPIYYPNGKPHIGHAYTTIAADALARYKRLQGYDV-----FFLTGTdehgqKIQQAAEK-AGKTPQE---Y---- 71
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 805387474 108 gipgdilptLDtpeKIVDYFKrESEKAMrNIGYSidwrrKFT-TTDPTYKKFIewQYI--RLEEKGLIVKG 175
Cdd:PRK12267 72 ---------VD---EISAGFK-ELWKKL-DISYD-----KFIrTTDERHKKVV--QKIfeKLYEQGDIYKG 121
|
|
| Anticodon_Ia_Val |
cd07962 |
Anticodon-binding domain of valyl tRNA synthetases; This domain is found in valyl tRNA ... |
670-786 |
1.37e-09 |
|
Anticodon-binding domain of valyl tRNA synthetases; This domain is found in valyl tRNA synthetases (ValRS), which belong to the class Ia aminoacyl tRNA synthetases. It lies C-terminal to the catalytic core domain, and recognizes and specifically binds to the tRNA anticodon. ValRS catalyzes the transfer of valine to the 3'-end of its tRNA.
Pssm-ID: 153416 [Multi-domain] Cd Length: 135 Bit Score: 57.18 E-value: 1.37e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 670 DWQRtgIESARRqvdrF-------YSFANSVIESGKRADLSTE-LKQIDHWILSRIQNYIRDTNAAL----YSIQTReAI 737
Cdd:cd07962 2 DEKR--VEGGRN----FcnklwnaARFVLMNLEDDDEPEEDPEsLSLADRWILSRLNKTVEEVTEALenyrFSEAAT-AL 74
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 805387474 738 QNsFFLlqNDV-KWY--------------QRRGGETLLYYVLDNWVRLMSPFTPHLCEEIWEAM 786
Cdd:cd07962 75 YE-FFW--NDFcDWYlelvkprlygedeeEKKAARATLYYVLETILRLLHPFMPFITEELWQRL 135
|
|
| MetRS_core |
cd00814 |
catalytic core domain of methioninyl-tRNA synthetases; Methionine tRNA synthetase (MetRS) ... |
592-670 |
3.32e-09 |
|
catalytic core domain of methioninyl-tRNA synthetases; Methionine tRNA synthetase (MetRS) catalytic core domain. This class I enzyme aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. MetRS, which consists of the core domain and an anti-codon binding domain, functions as a monomer. However, in some species the anti-codon binding domain is followed by an EMAP domain. In this case, MetRS functions as a homodimer. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. As a result of a deletion event, MetRS has a significantly shorter core domain insertion than IleRS, ValRS, and LeuR. Consequently, the MetRS insertion lacks the editing function.
Pssm-ID: 173907 [Multi-domain] Cd Length: 319 Bit Score: 59.47 E-value: 3.32e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 592 GKDLVPNHLLFF-LFHHVAlfeEEKWPKALAVNGFVSLEGQKMSKSKGPILTMESAVSKYGADITRMYILSTAEQTQDAD 670
Cdd:cd00814 242 GKDIIRFHAIYWpAMLLGA---GLPLPTRIVAHGYLTVEGKKMSKSRGNVVDPDDLLERYGADALRYYLLRERPEGKDSD 318
|
|
| PLN02882 |
PLN02882 |
aminoacyl-tRNA ligase |
3-812 |
4.56e-09 |
|
aminoacyl-tRNA ligase
Pssm-ID: 215477 [Multi-domain] Cd Length: 1159 Bit Score: 60.51 E-value: 4.56e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 3 QDYKPHEIEKKWQKKWNESQIFQAE----PDKREKFFITIPyPYLNGNLHAGHTRTFTIGDVVARHKRMLGYNVLYPMGF 78
Cdd:PLN02882 6 KDFSFPKQEEKILSLWSEIDAFKTQlkrtEGLPEYIFYDGP-PFATGLPHYGHILAGTIKDIVTRYQSMTGHHVTRRFGW 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 79 HVTGTPIVglAEL-----IANRDpqtmDVYERlhGIPgdilPTLDTPEKIVDYFKRESEKAMRNIGYSIDWRRKFTTTDP 153
Cdd:PLN02882 85 DCHGLPVE--YEIdkklgIKRRD----DVLKM--GID----KYNEECRSIVTRYSKEWEKTVTRTGRWIDFENDYKTMDP 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 154 TYKKFIEWQYIRLEEKGLIVKGSHPVKWCPNDNNPvedhdiLHGEEATIveytlikfRYKDL----------VLPCA--- 220
Cdd:PLN02882 153 KFMESVWWVFKQLFEKGLVYKGFKVMPYSTACKTP------LSNFEAGL--------NYKDVsdpavmvsfpIVGDPdna 218
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 221 -----TLRPETTYGVTNLWVNPDVTYVKAK---------VTQGENEEFWVVSKEAFRKLTFTDRTVEY--IEDVPAKSII 284
Cdd:PLN02882 219 sfvawTTTPWTLPSNLALCVNPNFTYVKVRnkytgkvyiVAESRLSALPTAKPKSKKGSKPENAAEGYevLAKVPGSSLV 298
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 285 GIKLTnPV------TGDEIISLPA-SFVRPENGSGIVMSVPAHAPFDY-LALrdlydadlsEYGITEDLRNIklisLIKV 356
Cdd:PLN02882 299 GKKYE-PLfdyfseFSDTAFRVVAdDYVTDDSGTGVVHCAPAFGEDDYrVCL---------ANGIIEKGGNL----PVPV 364
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 357 PEFGEFPAKeivesmgITSQKDPKAEEATKIVyrrefhggvlkeltgkyegqaVSKIKDilTRDFISSNAgetfYEFSEP 436
Cdd:PLN02882 365 DDDGCFTEK-------VTDFSGRYVKDADKDI---------------------IAAIKA--KGRLVKSGS----ITHSYP 410
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 437 VVCRCGTPCVVNMVKgQWFLNYSnpEWKAKVYKCLDEMRIIP---EEYRveFENkvdWL---KDKACARRKGLGTRLPFd 510
Cdd:PLN02882 411 FCWRSDTPLIYRAVP-SWFVKVE--EIKDRLLENNKQTYWVPdyvKEKR--FHN---WLenaRDWAVSRSRFWGTPLPI- 481
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 511 keWLIESlGDSTIYMSyyVIARFIENGELKIENLTLSFFDYVLLGKSdlaaasadTGLSPELLEEIRRHFNYWY------ 584
Cdd:PLN02882 482 --WISDD-GEEVVVIG--SIAELEKLSGVKVTDLHRHFIDHITIPSS--------RGPEFGVLRRVDDVFDCWFesgsmp 548
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 585 ------------------PVDLRSSGKDLVPNHLLFFLFHHVALFEEEKWpKALAVNGFVSLE-GQKMSKSKGPILTMES 645
Cdd:PLN02882 549 yayihypfenkelfeknfPADFVAEGLDQTRGWFYTLMVLSTALFDKPAF-KNLICNGLVLAEdGKKMSKSLKNYPDPNE 627
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 646 AVSKYGADITRMYILST----AEQTQdadWQRTGIESARRQVdrFYSFANS---VIESGKRADLS-------TELKQI-- 709
Cdd:PLN02882 628 VIDKYGADALRLYLINSpvvrAEPLR---FKEEGVFGVVKDV--FLPWYNAyrfLVQNAKRLEVEggapfvpLDLAKLqn 702
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 710 -----DHWILSRIQN---YIRDTNAA--LYSIQTREAiqnSFflLQNDVKWYQR--------RGGE-------TLLYYVL 764
Cdd:PLN02882 703 sanvlDRWINSATQSlvkFVREEMGAyrLYTVVPYLV---KF--IDNLTNIYVRfnrkrlkgRTGEedcrtalSTLYNVL 777
|
890 900 910 920 930
....*....|....*....|....*....|....*....|....*....|...
gi 805387474 765 DNWVRLMSPFTPHLCEEIWEAM-----GHKDPISLAQYPLYNEDLIDDGAELA 812
Cdd:PLN02882 778 LTSCKVMAPFTPFFTEVLYQNLrkvlpGSEESIHYCSFPQVDEGELDERIEQS 830
|
|
| tRNA-synt_1g |
pfam09334 |
tRNA synthetases class I (M); This family includes methionyl tRNA synthetases. |
592-670 |
1.36e-08 |
|
tRNA synthetases class I (M); This family includes methionyl tRNA synthetases.
Pssm-ID: 401322 [Multi-domain] Cd Length: 387 Bit Score: 58.07 E-value: 1.36e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 592 GKDLVPNHLLFFlfhhVALFEEEKW--PKALAVNGFVSLEGQKMSKSKGPILTMESAVSKYGADITRMYILSTAEQTQDA 669
Cdd:pfam09334 286 GKDIIYFHTIFW----PAMLLGAGYrlPTTVFAHGYLTYEGGKMSKSRGNVVWPSEALDRFPPDALRYYLARNRPETKDT 361
|
.
gi 805387474 670 D 670
Cdd:pfam09334 362 D 362
|
|
| metG |
PRK00133 |
methionyl-tRNA synthetase; Reviewed |
592-787 |
1.83e-08 |
|
methionyl-tRNA synthetase; Reviewed
Pssm-ID: 234655 [Multi-domain] Cd Length: 673 Bit Score: 58.24 E-value: 1.83e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 592 GKDLVPNHLLFFlfhhVALFEEEKW--PKALAVNGFVSLEGQKMSKSKGPILTMESAVSKYGADITRMYILSTA-EQTQD 668
Cdd:PRK00133 291 GKDIIYFHTLFW----PAMLEGAGYrlPTNVFAHGFLTVEGAKMSKSRGTFIWARTYLDHLDPDYLRYYLAAKLpETIDD 366
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 669 AD--W----QRTGIEsarrQVDRFYSFANSVIE-SGKRADLSTELKQIDHWILSRIQNYIRDTNAALYSIQTREAIQ--- 738
Cdd:PRK00133 367 LDfnWedfqQRVNSE----LVGKVVNFASRTAGfINKRFDGKLPDALADPELLEEFEAAAEKIAEAYEAREFRKALReim 442
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 805387474 739 ------NSFFllqNDVK-WYQ-----RRGGETLlyYVLDNWVR----LMSPFTPHLCEEIWEAMG 787
Cdd:PRK00133 443 aladfaNKYV---DDNEpWKLakqdgERLQAVC--SVGLNLFRalaiYLKPVLPELAERAEAFLN 502
|
|
| metG |
PRK00133 |
methionyl-tRNA synthetase; Reviewed |
33-186 |
5.25e-08 |
|
methionyl-tRNA synthetase; Reviewed
Pssm-ID: 234655 [Multi-domain] Cd Length: 673 Bit Score: 56.70 E-value: 5.25e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 33 KFFITIPYPYLNGNLHAGHTRTFTIGDVVARHKRMLGYNVLYPMGFHVTGTPIVGLAElianrdpqtmdvyerLHGIpgd 112
Cdd:PRK00133 3 KILVTCALPYANGPIHLGHLVEYIQADIWVRYQRMRGHEVLFVCADDAHGTPIMLKAE---------------KEGI--- 64
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 805387474 113 ilptldTPEKIVDYFKRESEKAMRNIGYSID-WRRkftTTDPTYKKFIEWQYIRLEEKGLIVKGSHPVKWCPNDN 186
Cdd:PRK00133 65 ------TPEELIARYHAEHKRDFAGFGISFDnYGS---THSEENRELAQEIYLKLKENGYIYEKTIEQLYDPEKG 130
|
|
| IleRS_core |
cd00818 |
catalytic core domain of isoleucyl-tRNA synthetases; Isoleucine amino-acyl tRNA synthetases ... |
608-668 |
8.54e-08 |
|
catalytic core domain of isoleucyl-tRNA synthetases; Isoleucine amino-acyl tRNA synthetases (IleRS) catalytic core domain . This class I enzyme is a monomer which aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. IleRS has an insertion in the core domain, which is subject to both deletions and rearrangements. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids.
Pssm-ID: 173909 [Multi-domain] Cd Length: 338 Bit Score: 55.32 E-value: 8.54e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 805387474 608 VALFEEEKWpKALAVNGFVSLE-GQKMSKSKGPILTMESAVSKYGADITRMYILSTAEQTQD 668
Cdd:cd00818 275 TALFGKAPY-KNVIVHGFVLDEdGRKMSKSLGNYVDPQEVVDKYGADALRLWVASSDVYAED 335
|
|
| Anticodon_Ia_Leu_BEm |
cd07958 |
Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; ... |
671-786 |
9.14e-08 |
|
Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; This domain is found in leucyl tRNA synthetases (LeuRS), which belong to the class Ia aminoacyl tRNA synthetases. It lies C-terminal to the catalytic core domain. In contrast to other class Ia enzymes, the anticodon is not used as an identity element in LeuRS (with exceptions such as Saccharomyces cerevisiae and some other eukaryotes). No anticodon-binding site can be defined for this family, which includes bacterial and eukaryotic mitochondrial members, as well as LeuRS from the archaeal Halobacteria. LeuRS catalyzes the transfer of leucine to the 3'-end of its tRNA.
Pssm-ID: 153412 [Multi-domain] Cd Length: 117 Bit Score: 51.45 E-value: 9.14e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 671 WQRTGIESARRQVDRFYSFANSVIESGKRADLSTELKQIDhwilsriQNYIRDTNAALYSIqtREAIQN-SF-------- 741
Cdd:cd07958 1 WSDSGVEGAYRFLNRVWRLVTELAEALAAPAAAAELSEED-------KELRRKLHKTIKKV--TEDIERlRFntaiaalm 71
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 805387474 742 -FLlqNDVKWYQRRGGE--TLLYYVLDNWVRLMSPFTPHLCEEIWEAM 786
Cdd:cd07958 72 eLV--NALYKYKKKDAQhaAVLREALETLVLLLAPFAPHIAEELWEEL 117
|
|
| PTZ00427 |
PTZ00427 |
isoleucine-tRNA ligase, putative; Provisional |
9-786 |
6.71e-07 |
|
isoleucine-tRNA ligase, putative; Provisional
Pssm-ID: 173617 [Multi-domain] Cd Length: 1205 Bit Score: 53.43 E-value: 6.71e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 9 EIEKKWQKKWNESQIF----QAEPDKREKFFITIPyPYLNGNLHAGHTRTFTIGDVVARHKRMLGYNVLYPMGFHVTGTP 84
Cdd:PTZ00427 76 EEEEKVLKYWKSIDAFntsnKLAKNKKAYIFYDGP-PFATGLPHYGHLLAGIIKDCVTRYFYQCGFSVERKFGWDCHGLP 154
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 85 IVGLAELIANRDPQT------MDVYErlhgipgdilptlDTPEKIVDYFKRESEKAMRNIGYSIDWRRKFTTTDPTYKKF 158
Cdd:PTZ00427 155 IEYEIEKENNINKKEdilkmgIDVYN-------------EKCRGIVLKYSNEWVKTVERIGRWIDFKNDYKTMDKTFMES 221
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 159 IEWQYIRLEEKGLIVKGSHPVKWCPNDNNPVEDHDILHGEEAT-----IVEYTL------------IKFRYKDLVLPCAT 221
Cdd:PTZ00427 222 VWWVFSELYKNNYVYKSFKVMPYSCKCNTPISNFELNLNYKDTpdpsiIISFVLcsdfpkveeecnIEEDKQLLGEKYSV 301
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 222 LRPETTygvtNLWVNPDVTYVKAKVTQGENEEF-WVVS------------KEAF-----------RKLTFTDRTVEYIED 277
Cdd:PTZ00427 302 LYNNKR----ENSNNGNNNSTNNVCYAQHSEILaWTTTpwtlpsnlalcvNEHFtylrihhvksnRVVIVGECRLEWIMK 377
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 278 VPAKSIIGIKLTNPVTGDEIISL-----------------------PASFVRPENGSGIVMSVPAHAPFDYLALRDlyda 334
Cdd:PTZ00427 378 ELKWNVEDLKIVNRFKGKELKGLrykplftnfyekynfkeraykilADDFVTDDAGTGIVHCAPTYGEDDFRVCKK---- 453
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 335 dlseYGITEDLRNIkLISLIKVPefGEFPAK-EIVESMGItsqkdpkaEEATKIVYRRefhggvLKEltgkyegqavski 413
Cdd:PTZ00427 454 ----NGVIDPEKNI-FIDPLDAN--GYFTNEvEEVQNLYI--------KEADNVIKKK------LKN------------- 499
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 414 kdilTRDFISSNAgetfYEFSEPVVCRCGTPCVVNMVKGqWFLNYSNPewKAKVYKCLDEMRIIPEEYR-VEFENKVDWL 492
Cdd:PTZ00427 500 ----ENRLLSNNT----IVHSYPFCWRSDTPLIYRAIPA-WFIRVSNS--TNELVKNNETTYWIPAHIKeKKFHNWIKDA 568
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 493 KDKACARRKGLGTRLPFdkeWLIESLGDSTIYMSyyvIARFIE-NGELKIENLTLSFFDYVLL----GK--------SDL 559
Cdd:PTZ00427 569 KDWCISRNRYWGTPIPI---WADEKMETVICVES---IKHLEElSGVKNINDLHRHFIDHIEIknpkGKtypklkriPEV 642
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 560 AAASADTGLSPEL-----LEEIRRHFNYWYPVDLRSSGKDLVPNHLLFFLFHHVALFEEEKWpKALAVNGFV-SLEGQKM 633
Cdd:PTZ00427 643 FDCWFESGSMPYAkvhypFSTEKEDFHKIFPADFIAEGLDQTRGWFYTLLVISTLLFDKAPF-KNLICNGLVlASDGKKM 721
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 634 SKSKGPILTMESAVSKYGADITRMYIL-STAEQTQDADWQRTGIESARRQVD-------RFYSFANSVIESGKRADLSTE 705
Cdd:PTZ00427 722 SKRLKNYPDPLYILDKYGADSLRLYLInSVAVRAENLKFQEKGVNEVVKSFIlpfyhsfRFFSQEVTRYECLNKKQFLFN 801
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 706 LKQI-------DHWILSRIQNYIRDTNAALYSIQTREAIQNSFFLLQNDVKWYQR------RG--GE-------TLLYYV 763
Cdd:PTZ00427 802 TDYIykndnimDQWIFSSVQSLTKSVHTEMKAYKLYNVLPKLLQFIENLTNWYIRlnrdrmRGslGEenclqslCTTYRT 881
|
890 900
....*....|....*....|...
gi 805387474 764 LDNWVRLMSPFTPHLCEEIWEAM 786
Cdd:PTZ00427 882 LHLFTVLMAPFTPFITEYIYQQL 904
|
|
| CysRS_core |
cd00672 |
catalytic core domain of cysteinyl tRNA synthetase; Cysteinyl tRNA synthetase (CysRS) ... |
623-662 |
2.81e-06 |
|
catalytic core domain of cysteinyl tRNA synthetase; Cysteinyl tRNA synthetase (CysRS) catalytic core domain. This class I enzyme is a monomer which aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding.
Pssm-ID: 173899 [Multi-domain] Cd Length: 213 Bit Score: 49.11 E-value: 2.81e-06
10 20 30 40
....*....|....*....|....*....|....*....|
gi 805387474 623 NGFVSLEGQKMSKSKGPILTMESAVSKYGADITRMYILST 662
Cdd:cd00672 165 TGHLTIDGEKMSKSLGNFITVRDALKKYDPEVLRLALLSS 204
|
|
| tRNA-synt_1_2 |
pfam13603 |
Leucyl-tRNA synthetase, Domain 2; This is a family of the conserved region of Leucine-tRNA ... |
221-320 |
3.45e-06 |
|
Leucyl-tRNA synthetase, Domain 2; This is a family of the conserved region of Leucine-tRNA ligase or Leucyl-tRNA synthetase, EC:6.1.1.4.
Pssm-ID: 433342 [Multi-domain] Cd Length: 185 Bit Score: 48.31 E-value: 3.45e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 221 TLRPETTYGVTNLWVNPDVTYVKaKVTQgENEEFwvvskEAF-RKLTFTDRTVEYIEDVPAKSI-IGIKLTNPVTGDEII 298
Cdd:pfam13603 27 TTRPDTLMGVTFVALAPEHPLVE-KLAE-KNPEV-----AAFiEECKNTSEIERTSETKEKEGVfTGLYAIHPITGEKIP 99
|
90 100
....*....|....*....|..
gi 805387474 299 SLPASFVRPENGSGIVMSVPAH 320
Cdd:pfam13603 100 IWIANFVLMEYGTGAVMAVPAH 121
|
|
| tRNA-synt_1e |
pfam01406 |
tRNA synthetases class I (C) catalytic domain; This family includes only cysteinyl tRNA ... |
584-681 |
6.82e-06 |
|
tRNA synthetases class I (C) catalytic domain; This family includes only cysteinyl tRNA synthetases.
Pssm-ID: 396128 [Multi-domain] Cd Length: 301 Bit Score: 48.90 E-value: 6.82e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 584 YPVDLRSSGKDLVPNHLLFFLFHHVALFEEEkWPKALAVNGFVSLEGQKMSKSKGPILTMESAVSKYGADITRMYILSTA 663
Cdd:pfam01406 206 DQIDIHGGGIDLAFPHHENEIAQSEAAFDKQ-LANYWLHNGHVMIDGEKMSKSLGNFFTIRDVLKRYDPEILRYFLLSVH 284
|
90
....*....|....*...
gi 805387474 664 EQTQdADWQRTGIESARR 681
Cdd:pfam01406 285 YRSP-LDFSEELLEQAKS 301
|
|
| Anticodon_Ia_like |
cd07375 |
Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; This ... |
675-775 |
2.19e-05 |
|
Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; This domain is found in a variety of class Ia aminoacyl tRNA synthetases, C-terminal to the catalytic core domain. It recognizes and specifically binds to the anticodon of the tRNA. Aminoacyl tRNA synthetases catalyze the transfer of cognate amino acids to the 3'-end of their tRNAs by specifically recognizing cognate from non-cognate amino acids. Members include valyl-, leucyl-, isoleucyl-, cysteinyl-, arginyl-, and methionyl-tRNA synthethases. This superfamily also includes a domain from MshC, an enzyme in the mycothiol biosynthetic pathway.
Pssm-ID: 153408 [Multi-domain] Cd Length: 117 Bit Score: 44.80 E-value: 2.19e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 675 GIESARRQVDRFY---SFANSVIESGKRADLSTELKQIDHWILSRIQNYIRDTNAALYSIQTREAIQNSFFLLqNDVKWY 751
Cdd:cd07375 3 RLKQARAFLNRLYrllSFFRKALGGTQPKWDNELLEEADRELLARLQEFIKRTTNALEALDPTTAVQELFKFT-NELNWY 81
|
90 100 110
....*....|....*....|....*....|....*.
gi 805387474 752 QRRGGE------------TLLYYVLDNWVRLMSPFT 775
Cdd:cd07375 82 LDELKPalqteelreavlAVLRAALVVLTKLLAPFT 117
|
|
| PRK12267 |
PRK12267 |
methionyl-tRNA synthetase; Reviewed |
580-787 |
2.29e-05 |
|
methionyl-tRNA synthetase; Reviewed
Pssm-ID: 237028 [Multi-domain] Cd Length: 648 Bit Score: 48.26 E-value: 2.29e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 580 FNYWYPVDLRSSGKDLVPNHLLF---FLfhhVALfeEEKWPKALAVNGFVSLEGQKMSKSKGPILTMESAVSKYGADITR 656
Cdd:PRK12267 249 FKKFWPADVHLVGKDILRFHAIYwpiML---MAL--GLPLPKKVFAHGWWLMKDGKMSKSKGNVVDPEELVDRYGLDALR 323
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 657 MYILSTAEQTQDADWqrtgieSARRQVDRF-YSFAN----------SVIE--SGKRADLSTELKQIDHWILSRIQNYIRD 723
Cdd:PRK12267 324 YYLLREVPFGSDGDF------SPEALVERInSDLANdlgnllnrtvAMINkyFDGEIPAPGNVTEFDEELIALAEETLKN 397
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 724 TNAALYSIQTREAIQNSFFL---------------LQNDVKWYQRRGgeTLLYYVLDNwVR----LMSPFTPHLCEEIWE 784
Cdd:PRK12267 398 YEELMEELQFSRALEEVWKLisrankyidetapwvLAKDEGKKERLA--TVMYHLAES-LRkvavLLSPFMPETSKKIFE 474
|
...
gi 805387474 785 AMG 787
Cdd:PRK12267 475 QLG 477
|
|
| PLN02224 |
PLN02224 |
methionine-tRNA ligase |
581-692 |
4.90e-04 |
|
methionine-tRNA ligase
Pssm-ID: 177869 [Multi-domain] Cd Length: 616 Bit Score: 43.93 E-value: 4.90e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 581 NYWYPVDLRSSGKDLVPNHLLFF--LFHHVALfeeeKWPKALAVNGFVSLEGQKMSKSKGPILTMESAVSKYGADITRMY 658
Cdd:PLN02224 317 SFGWPASLHLIGKDILRFHAVYWpaMLMSAGL----ELPKMVFGHGFLTKDGMKMGKSLGNTLEPFELVQKFGPDAVRYF 392
|
90 100 110
....*....|....*....|....*....|....
gi 805387474 659 ILSTAEQTQDADWQRtgiesarrqvDRFYSFANS 692
Cdd:PLN02224 393 FLREVEFGNDGDYSE----------DRFIKIVNA 416
|
|
| PLN02224 |
PLN02224 |
methionine-tRNA ligase |
29-184 |
9.14e-04 |
|
methionine-tRNA ligase
Pssm-ID: 177869 [Multi-domain] Cd Length: 616 Bit Score: 43.16 E-value: 9.14e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 805387474 29 DKREKFFITIPYPYLNGNLHAGHTRTFTIGDVVARHKRMLGYNVLYPMGFHVTGTPIVGLAELIANRDPQTMDVyerlhg 108
Cdd:PLN02224 66 DEADTFVLTTPLYYVNAPPHMGSAYTTIAADSIARFQRLLGKKVIFITGTDEHGEKIATSAAANGRNPPEHCDI------ 139
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 805387474 109 ipgdILPTLDTPEKIVDyfkresekamrnigysIDWRRKFTTTDPTYKKFIEWQYIRLEEKGLIVKGSHPVKWCPN 184
Cdd:PLN02224 140 ----ISQSYRTLWKDLD----------------IAYDKFIRTTDPKHEAIVKEFYARVFANGDIYRADYEGLYCVN 195
|
|
| class_I_aaRS_core |
cd00802 |
catalytic core domain of class I amino acyl-tRNA synthetase; Class I amino acyl-tRNA ... |
36-74 |
3.35e-03 |
|
catalytic core domain of class I amino acyl-tRNA synthetase; Class I amino acyl-tRNA synthetase (aaRS) catalytic core domain. These enzymes are mostly monomers which aminoacylate the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding.
Pssm-ID: 173901 [Multi-domain] Cd Length: 143 Bit Score: 39.00 E-value: 3.35e-03
10 20 30
....*....|....*....|....*....|....*....
gi 805387474 36 ITIPYPYLNGNLHAGHTRTFTIGDVVARHKRMLGYNVLY 74
Cdd:cd00802 1 TTFSGITPNGYLHIGHLRTIVTFDFLAQAYRKLGYKVRC 39
|
|
| cysS |
PRK14535 |
cysteinyl-tRNA synthetase; Provisional |
623-688 |
4.88e-03 |
|
cysteinyl-tRNA synthetase; Provisional
Pssm-ID: 173001 [Multi-domain] Cd Length: 699 Bit Score: 40.86 E-value: 4.88e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 805387474 623 NGFVSLEGQKMSKSKGPILTMESAVSKYGADITRMYILStAEQTQDADWQRTGIESARRQVDRFYS 688
Cdd:PRK14535 499 NGFIRVDGEKMSKSLGNFFTIREVLKQYDPEVVRFFILR-AHYRSPLNYSDAHLDDAKGALTRLYT 563
|
|
| argS |
TIGR00456 |
arginyl-tRNA synthetase; This model recognizes arginyl-tRNA synthetase in every completed ... |
30-73 |
9.33e-03 |
|
arginyl-tRNA synthetase; This model recognizes arginyl-tRNA synthetase in every completed genome to date. An interesting feature of the alignment of all arginyl-tRNA synthetases is a fairly deep split between two families. One family includes archaeal, eukaryotic and organellar, spirochete, E. coli, and Synechocystis sp. The second, sharing a deletion of about 25 residues in the central region relative to the first, includes Bacillus subtilis, Aquifex aeolicus, the Mycoplasmas and Mycobacteria, and the Gram-negative bacterium Helicobacter pylori. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273085 [Multi-domain] Cd Length: 563 Bit Score: 39.63 E-value: 9.33e-03
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 805387474 30 KREKFFITIPYPYLNGNLHAGHTRTFTIGDVVARHKRMLGYNVL 73
Cdd:TIGR00456 110 KNKKIIIEFSSANPAGPLHVGHLRNAIIGDSLARILEFLGYDVI 153
|
|
| |
