NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|913612348|gb|AKU94880|]
View 

Oxidoreductase [Labilithrix luteola]

Protein Classification

isopenicillin N synthase family dioxygenase( domain architecture ID 11466022)

isopenicillin N synthase family oxygenase similar to isopenicillin N synthase, which removes hydrogen atoms from delta-L-(alpha-aminoadipyl)-L-cysteinyl-D-valine (ACV) to form the azetidinone and thiazolidine rings of isopenicillin; may be 2-oxoglutarate and iron-dependent

EC:  1.-.-.-
Gene Ontology:  GO:0046872|GO:0051213|GO:0005506

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
PcbC COG3491
Isopenicillin N synthase and related dioxygenases [Secondary metabolites biosynthesis, ...
 1-344 2.30e-103

Isopenicillin N synthase and related dioxygenases [Secondary metabolites biosynthesis, transport and catabolism];


:

Pssm-ID: 442714 [Multi-domain]  Cd Length: 320  Bit Score: 307.12  E-value: 2.30e-103
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913612348   1 MSQPSIPTVDLADLRSNDPSRIASASAAIREAFGTYGLVYVMNHGVDPNGVSRVYDEFRTLSQQPVAEKQKLARPDLWFQ 80
Cdd:COG3491    2 TSFSSIPVIDLSPLRSGDPADRAAFAAELGEACREVGFFYVTGHGIPAELIDRLYAAARRFFALPEEEKLKYAIPGSPGQ 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913612348  81 RGWTPPNTEIAvAAGGQPDFKECYFMAPY--ESDPvleAQYPELYPPNIWPEGMTAFREEYTKMGRALHEAGLALLRGAA 158
Cdd:COG3491   82 RGYTPFGGETA-KGAKPPDLKEFFDIGRElpPDDP---DAGPPLYGPNQWPEELPGFREAVLAYYAALEALGRRLLRAFA 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913612348 159 HALGLAPNTFTDICEGGAHVTRILHYLALSPEqVNTGILWGEEHTDFNLLTLLPGgrfvdptgnvapkpDDKSGLFLRTR 238
Cdd:COG3491  158 LALGLPEDYFDDLFDDPNSILRLIHYPPQPAP-PPPGQVGAGAHTDYGLLTLLLQ--------------DDVGGLQVLTR 222

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913612348 239 gtpenpAGVQVRGRPPEGCIVAQIGQQLEMLTGGVFVATPHVITAPGvPGWTRDSSAHFMHASANSVLFPLEKFQTPAAR 318
Cdd:COG3491  223 ------DGEWIDAPPVPGAFVVNIGDMLERWTNGRLRSTPHRVVNPA-AGRERYSIPFFLHPNPDAVIEPLPSCVTADDP 295

                        330       340
                 ....*....|....*....|....*.
gi 913612348 319 SAYrPPVLAGTYAIKTLVDIGLAPKA 344
Cdd:COG3491  296 ARY-EPITAGDYLKERLAEIGLYRKA 320
 
Name Accession Description Interval E-value
PcbC COG3491
Isopenicillin N synthase and related dioxygenases [Secondary metabolites biosynthesis, ...
 1-344 2.30e-103

Isopenicillin N synthase and related dioxygenases [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 442714 [Multi-domain]  Cd Length: 320  Bit Score: 307.12  E-value: 2.30e-103
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913612348   1 MSQPSIPTVDLADLRSNDPSRIASASAAIREAFGTYGLVYVMNHGVDPNGVSRVYDEFRTLSQQPVAEKQKLARPDLWFQ 80
Cdd:COG3491    2 TSFSSIPVIDLSPLRSGDPADRAAFAAELGEACREVGFFYVTGHGIPAELIDRLYAAARRFFALPEEEKLKYAIPGSPGQ 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913612348  81 RGWTPPNTEIAvAAGGQPDFKECYFMAPY--ESDPvleAQYPELYPPNIWPEGMTAFREEYTKMGRALHEAGLALLRGAA 158
Cdd:COG3491   82 RGYTPFGGETA-KGAKPPDLKEFFDIGRElpPDDP---DAGPPLYGPNQWPEELPGFREAVLAYYAALEALGRRLLRAFA 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913612348 159 HALGLAPNTFTDICEGGAHVTRILHYLALSPEqVNTGILWGEEHTDFNLLTLLPGgrfvdptgnvapkpDDKSGLFLRTR 238
Cdd:COG3491  158 LALGLPEDYFDDLFDDPNSILRLIHYPPQPAP-PPPGQVGAGAHTDYGLLTLLLQ--------------DDVGGLQVLTR 222

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913612348 239 gtpenpAGVQVRGRPPEGCIVAQIGQQLEMLTGGVFVATPHVITAPGvPGWTRDSSAHFMHASANSVLFPLEKFQTPAAR 318
Cdd:COG3491  223 ------DGEWIDAPPVPGAFVVNIGDMLERWTNGRLRSTPHRVVNPA-AGRERYSIPFFLHPNPDAVIEPLPSCVTADDP 295

                        330       340
                 ....*....|....*....|....*.
gi 913612348 319 SAYrPPVLAGTYAIKTLVDIGLAPKA 344
Cdd:COG3491  296 ARY-EPITAGDYLKERLAEIGLYRKA 320
DIOX_N pfam14226
non-haem dioxygenase in morphine synthesis N-terminal; This is the highly conserved N-terminal ...
 6-130 4.94e-25

non-haem dioxygenase in morphine synthesis N-terminal; This is the highly conserved N-terminal region of proteins with 2-oxoglutarate/Fe(II)-dependent dioxygenase activity.


Pssm-ID: 464110 [Multi-domain]  Cd Length: 116  Bit Score: 97.74  E-value: 4.94e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913612348    6 IPTVDLADLRsnDPSRIASASAAIREAFGTYGLVYVMNHGVDPNGVSRVYDEFRTLSQQPVAEKQKLARPDlwFQRGWTP 85
Cdd:pfam14226   1 IPVIDLSPLG--DPEDRAAVAAQLREACREWGFFQLVNHGVPEELIDELFEAAREFFALPLEEKLKYANPP--SFRGYGR 76

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 913612348   86 PNTEIavAAGGQPDFKECYFMAPYESDPVLEaqypELYPPNIWPE 130
Cdd:pfam14226  77 LGVES--TDGKKLDWKEFFDLGTELPADPPL----PLRGPNQWPE 115
PTZ00273 PTZ00273
oxidase reductase; Provisional
 1-337 7.04e-25

oxidase reductase; Provisional


Pssm-ID: 140299 [Multi-domain]  Cd Length: 320  Bit Score: 102.91  E-value: 7.04e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913612348   1 MSQPSIPTVDLADLRSNDPSRIASASAAIREAFGTYGLVYVMNHGVDPNGVSRVYDEFRTLSQQPVAEKQKLARPDLWFQ 80
Cdd:PTZ00273   1 MTRASLPVIDVSPLFGGESAEKMRVAKQIDEACRTWGFFYIVGHPIPQERIEKVLKMAKTFFSLPMEEKLKIDIRKSRLH 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913612348  81 RGWTPPNTEiAVAAGGQPDFKECYFMAPY--ESDPVLEAQYPeLYPPNIWPEGMTAFREEYTKMGRALHEAGLALLRGAA 158
Cdd:PTZ00273  81 RGYGAFGAE-QLDPSKPYDYKETFDMGCHlpKDHPDVMAGKP-LRGPNNHPTQVEGWMELMETHYRDMQALALVLLRALA 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913612348 159 HALGLAPNTFTDICEGGAHVTRILHYLALsPEQVNTGILWGeEHTDFNLLTLLpggrFVDPTGnvapkpddksGLFLRtr 238
Cdd:PTZ00273 159 LAIGLREDFFDSKFMEPLSVFRMKHYPAL-PQTKKGRTVCG-EHTDYGIITLL----YQDSVG----------GLQVR-- 220

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913612348 239 gtpeNPAGVQVRGRPPEGCIVAQIGQQLEMLTGGVFVATPHVITAPGVpgwTRDSSAHFMHASANSVLFPLEKFQTPAAR 318
Cdd:PTZ00273 221 ----NLSGEWMDVPPLEGSFVVNIGDMMEMWSNGRYRSTPHRVVNTGV---ERYSMPFFCEPNPNVIIKCLDNCHSEENP 293

                        330
                 ....*....|....*....
gi 913612348 319 SAYrPPVLAGTYAIKTLVD 337
Cdd:PTZ00273 294 PKY-PPVRAVDWLLKRFAE 311
 
Name Accession Description Interval E-value
PcbC COG3491
Isopenicillin N synthase and related dioxygenases [Secondary metabolites biosynthesis, ...
 1-344 2.30e-103

Isopenicillin N synthase and related dioxygenases [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 442714 [Multi-domain]  Cd Length: 320  Bit Score: 307.12  E-value: 2.30e-103
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913612348   1 MSQPSIPTVDLADLRSNDPSRIASASAAIREAFGTYGLVYVMNHGVDPNGVSRVYDEFRTLSQQPVAEKQKLARPDLWFQ 80
Cdd:COG3491    2 TSFSSIPVIDLSPLRSGDPADRAAFAAELGEACREVGFFYVTGHGIPAELIDRLYAAARRFFALPEEEKLKYAIPGSPGQ 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913612348  81 RGWTPPNTEIAvAAGGQPDFKECYFMAPY--ESDPvleAQYPELYPPNIWPEGMTAFREEYTKMGRALHEAGLALLRGAA 158
Cdd:COG3491   82 RGYTPFGGETA-KGAKPPDLKEFFDIGRElpPDDP---DAGPPLYGPNQWPEELPGFREAVLAYYAALEALGRRLLRAFA 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913612348 159 HALGLAPNTFTDICEGGAHVTRILHYLALSPEqVNTGILWGEEHTDFNLLTLLPGgrfvdptgnvapkpDDKSGLFLRTR 238
Cdd:COG3491  158 LALGLPEDYFDDLFDDPNSILRLIHYPPQPAP-PPPGQVGAGAHTDYGLLTLLLQ--------------DDVGGLQVLTR 222

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913612348 239 gtpenpAGVQVRGRPPEGCIVAQIGQQLEMLTGGVFVATPHVITAPGvPGWTRDSSAHFMHASANSVLFPLEKFQTPAAR 318
Cdd:COG3491  223 ------DGEWIDAPPVPGAFVVNIGDMLERWTNGRLRSTPHRVVNPA-AGRERYSIPFFLHPNPDAVIEPLPSCVTADDP 295

                        330       340
                 ....*....|....*....|....*.
gi 913612348 319 SAYrPPVLAGTYAIKTLVDIGLAPKA 344
Cdd:COG3491  296 ARY-EPITAGDYLKERLAEIGLYRKA 320
DIOX_N pfam14226
non-haem dioxygenase in morphine synthesis N-terminal; This is the highly conserved N-terminal ...
 6-130 4.94e-25

non-haem dioxygenase in morphine synthesis N-terminal; This is the highly conserved N-terminal region of proteins with 2-oxoglutarate/Fe(II)-dependent dioxygenase activity.


Pssm-ID: 464110 [Multi-domain]  Cd Length: 116  Bit Score: 97.74  E-value: 4.94e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913612348    6 IPTVDLADLRsnDPSRIASASAAIREAFGTYGLVYVMNHGVDPNGVSRVYDEFRTLSQQPVAEKQKLARPDlwFQRGWTP 85
Cdd:pfam14226   1 IPVIDLSPLG--DPEDRAAVAAQLREACREWGFFQLVNHGVPEELIDELFEAAREFFALPLEEKLKYANPP--SFRGYGR 76

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 913612348   86 PNTEIavAAGGQPDFKECYFMAPYESDPVLEaqypELYPPNIWPE 130
Cdd:pfam14226  77 LGVES--TDGKKLDWKEFFDLGTELPADPPL----PLRGPNQWPE 115
PTZ00273 PTZ00273
oxidase reductase; Provisional
 1-337 7.04e-25

oxidase reductase; Provisional


Pssm-ID: 140299 [Multi-domain]  Cd Length: 320  Bit Score: 102.91  E-value: 7.04e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913612348   1 MSQPSIPTVDLADLRSNDPSRIASASAAIREAFGTYGLVYVMNHGVDPNGVSRVYDEFRTLSQQPVAEKQKLARPDLWFQ 80
Cdd:PTZ00273   1 MTRASLPVIDVSPLFGGESAEKMRVAKQIDEACRTWGFFYIVGHPIPQERIEKVLKMAKTFFSLPMEEKLKIDIRKSRLH 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913612348  81 RGWTPPNTEiAVAAGGQPDFKECYFMAPY--ESDPVLEAQYPeLYPPNIWPEGMTAFREEYTKMGRALHEAGLALLRGAA 158
Cdd:PTZ00273  81 RGYGAFGAE-QLDPSKPYDYKETFDMGCHlpKDHPDVMAGKP-LRGPNNHPTQVEGWMELMETHYRDMQALALVLLRALA 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913612348 159 HALGLAPNTFTDICEGGAHVTRILHYLALsPEQVNTGILWGeEHTDFNLLTLLpggrFVDPTGnvapkpddksGLFLRtr 238
Cdd:PTZ00273 159 LAIGLREDFFDSKFMEPLSVFRMKHYPAL-PQTKKGRTVCG-EHTDYGIITLL----YQDSVG----------GLQVR-- 220

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913612348 239 gtpeNPAGVQVRGRPPEGCIVAQIGQQLEMLTGGVFVATPHVITAPGVpgwTRDSSAHFMHASANSVLFPLEKFQTPAAR 318
Cdd:PTZ00273 221 ----NLSGEWMDVPPLEGSFVVNIGDMMEMWSNGRYRSTPHRVVNTGV---ERYSMPFFCEPNPNVIIKCLDNCHSEENP 293

                        330
                 ....*....|....*....
gi 913612348 319 SAYrPPVLAGTYAIKTLVD 337
Cdd:PTZ00273 294 PKY-PPVRAVDWLLKRFAE 311
PLN02485 PLN02485
oxidoreductase
 5-313 1.61e-15

oxidoreductase


Pssm-ID: 215267 [Multi-domain]  Cd Length: 329  Bit Score: 76.32  E-value: 1.61e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913612348   5 SIPTVDLADL--RSNDPSRIASASA---------AIREAfgtyGLVYVMNHGVDPNGVSRVYDEFRTLSQQPVAEKQKLA 73
Cdd:PLN02485   7 SIPVIDISPLvaKCDDPDMAEDPDVaevvrqldkACRDA----GFFYVKGHGISDSLIKKVREVTHEFFELPYEEKLKIK 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913612348  74 -RPDLWFqRGWTPPNTEIAvaaGGQPDFKE---CYfmAPYESDPVLEAQYPeLYPPNIWPEGMTAFR---EEYTKMGRAL 146
Cdd:PLN02485  83 mTPAAGY-RGYQRIGENVT---KGKPDMHEaidCY--REFKPGKYGDLGKV-MEGPNQWPENPQEFKalmEEYIKLCTDL 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913612348 147 HEAglaLLRGAAHALGLAPNTFTDICEGGAH-VTRILHYLALS--PEQVNTGILWGEeHTDFNLLTLLpggrfvdptgnv 223
Cdd:PLN02485 156 SRK---ILRGIALALGGSPDEFEGKMAGDPFwVMRIIGYPGVSnlNGPPENDIGCGA-HTDYGLLTLV------------ 219

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913612348 224 aPKPDDKSGLFLRtrgtpeNPAGVQVRGRPPEGCIVAQIGQQLEMLTGGVFVATPH-VI-TAPGVpgwtRDSSAHFMHAS 301
Cdd:PLN02485 220 -NQDDDITALQVR------NLSGEWIWAIPIPGTFVCNIGDMLKIWSNGVYQSTLHrVInNSPKY----RVCVAFFYETN 288

                        330
                 ....*....|..
gi 913612348 302 ANSVLFPLEKFQ 313
Cdd:PLN02485 289 FDAAVEPLDICK 300
PLN02393 PLN02393
leucoanthocyanidin dioxygenase like protein
 2-323 1.90e-11

leucoanthocyanidin dioxygenase like protein


Pssm-ID: 215220 [Multi-domain]  Cd Length: 362  Bit Score: 64.67  E-value: 1.90e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913612348   2 SQPSIPTVDLADLRSNDPSRIASASAAIREAFGTYGLVYVMNHGVDPNGVSRVYDEFRTLSQQPVAEKQKLARpdlwfqr 81
Cdd:PLN02393  48 AEINIPVIDLSSLFSDDARLRDATLRAISEACREWGFFQVVNHGVRPELMDRAREAWREFFHLPLEVKQRYAN------- 120

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913612348  82 gwTPPNTE-----IAVAAGGQPDFKECYFmapyesdpvLEAQYPELYPPNIWPEGMTAFREEYTKMGRALHEAGLALLRG 156
Cdd:PLN02393 121 --SPATYEgygsrLGVEKGAILDWSDYYF---------LHYLPSSLKDPNKWPSLPPSCRELIEEYGEEVVKLCGRLMKV 189

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913612348 157 AAHALGLAPNTFTDICEG----GAHVtRILHY---------LALSPeqvntgilwgeeHTDFNLLTLLpggrfvdptgnv 223
Cdd:PLN02393 190 LSVNLGLEEDRLQNAFGGedgvGACL-RVNYYpkcpqpdltLGLSP------------HSDPGGMTIL------------ 244

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913612348 224 apKPDDksglflrtrgtpeNPAGVQVRGR-------P-PEGCIVaQIGQQLEMLTGGVFVATPH-VITAPGVpgwTRDSS 294
Cdd:PLN02393 245 --LPDD-------------NVAGLQVRRDdawitvkPvPDAFIV-NIGDQIQVLSNAIYKSVEHrVIVNSAK---ERVSL 305

                        330       340
                 ....*....|....*....|....*....
gi 913612348 295 AHFMHASANSVLFPLEKFQTPAARSAYRP 323
Cdd:PLN02393 306 AFFYNPKSDLPIEPLKELVTPDRPALYPP 334
PLN00417 PLN00417
oxidoreductase, 2OG-Fe(II) oxygenase family protein
 1-323 2.45e-10

oxidoreductase, 2OG-Fe(II) oxygenase family protein


Pssm-ID: 177810 [Multi-domain]  Cd Length: 348  Bit Score: 61.13  E-value: 2.45e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913612348   1 MSQPSIPTVDLADL-RSNDPSRiaSASAAIREAFGTYGLVYVMNHGVDPNGVSRVYDEFRTLSQQPVAEKQKLARPDLWF 79
Cdd:PLN00417  40 VPEMDIPAIDLSLLlSSSDDGR--EELSKLHSALSTWGVVQVMNHGITEAFLDKIYKLTKQFFALPTEEKQKCAREIGSI 117

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913612348  80 QrGWtppNTEIAVAAGGQPDFKECYFMAPYESDpvlEAQYpelyppNIWPEGMTAFRE---EYTKMGRALHEaglALLRG 156
Cdd:PLN00417 118 Q-GY---GNDMILSDDQVLDWIDRLYLTTYPED---QRQL------KFWPQVPVGFREtlhEYTMKQRLVIE---KFFKA 181

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913612348 157 AAHALGLAPNTFTDIC-EGGAHVTRILHYLAL-SPEQVntgiLWGEEHTDFNLLTLLPggrfvdPTGNVAPKPDDKSGLF 234
Cdd:PLN00417 182 MARSLELEENCFLEMYgENATMDTRFNMYPPCpRPDKV----IGVKPHADGSAFTLLL------PDKDVEGLQFLKDGKW 251

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913612348 235 LRTRGTPENpagvqvrgrppegcIVAQIGQQLEMLTGGVFVATPHVITAPGVPgwTRDSSAHFMHASANSVLFPLEKFQT 314
Cdd:PLN00417 252 YKAPIVPDT--------------ILINVGDQMEIMSNGIYKSPVHRVVTNREK--ERISVATFCIPGADKEIQPVDGLVS 315


                 ....*....
gi 913612348 315 PAARSAYRP 323
Cdd:PLN00417 316 EARPRLYKT 324
PLN03178 PLN03178
leucoanthocyanidin dioxygenase; Provisional
 4-323 1.62e-09

leucoanthocyanidin dioxygenase; Provisional


Pssm-ID: 215614 [Multi-domain]  Cd Length: 360  Bit Score: 58.66  E-value: 1.62e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913612348   4 PSIPTVDLADLRSNDPSRIASASAAIREAFGTYGLVYVMNHGVDPNGVSRVYDEFRTLSQQPVAEKQKLAR-PDLWFQRG 82
Cdd:PLN03178  46 PQVPVVDLSNIESDDEVVREACVEAVRAAAAEWGVMHLVGHGIPADLLDRVRKAGEAFFRLPIEEKEKYANdQARGAAQG 125

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913612348  83 WtppNTEIAVAAGGQPDFKECYFmapyesdpvlEAQYPE-LYPPNIWPEGMTAFREEYTKMGRALHEAGLALLRGAAHAL 161
Cdd:PLN03178 126 Y---GSKLAANASGQLEWEDYFF----------HLTLPEdKRDPSLWPKTPPDYVPATSEYSRSLRSLATKLLAILSLGL 192

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913612348 162 GLAPNTFTDICEGGAHV---TRILHYLALSPEQVNTGIlwgEEHTDFNLLTLLpggrfvdptgnvapKPDDKSGLFLRTr 238
Cdd:PLN03178 193 GLPEDRLEKEVGGLEELllqMKINYYPRCPQPDLALGV---EAHTDVSALTFI--------------LHNMVPGLQVLY- 254

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913612348 239 gtpenpAGVQVRGRPPEGCIVAQIGQQLEMLTGGVFVATPH--VITAPGVpgwtRDSSAHFMHASANSVLF-PLEKFQTP 315
Cdd:PLN03178 255 ------EGKWVTAKCVPDSIVVHIGDTLEILSNGRYKSILHrgLVNKEKV----RISWAVFCEPPKEKIILkPLPELVSK 324


                 ....*...
gi 913612348 316 AARSAYRP 323
Cdd:PLN03178 325 EEPPKFPP 332
PLN02276 PLN02276
gibberellin 20-oxidase
 5-74 4.32e-09

gibberellin 20-oxidase


Pssm-ID: 215156 [Multi-domain]  Cd Length: 361  Bit Score: 57.29  E-value: 4.32e-09
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913612348   5 SIPTVDLADLRSNDPSRIASASAAIREAFGTYGLVYVMNHGVDPNGVSRVYDEFRTLSQQPVAEKQKLAR 74
Cdd:PLN02276  40 AVPLIDLGGFLSGDEAATAEAARLVREACLKHGFFQVVNHGVDAALIRAAHEYMDAFFKLPLSEKQRAQR 109
PLN02758 PLN02758
oxidoreductase, 2OG-Fe(II) oxygenase family protein
 2-279 6.43e-09

oxidoreductase, 2OG-Fe(II) oxygenase family protein


Pssm-ID: 215404 [Multi-domain]  Cd Length: 361  Bit Score: 56.76  E-value: 6.43e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913612348   2 SQPSIPTVDLADLRSNDPSRIASASAAIREAFGTYGLVYVMNHGVDPNGVSRVYDEFRTLSQQPVAEKQKLArpdlwfqr 81
Cdd:PLN02758  49 APDDIPVIDFSRLVKGDNDELFSEILKLRLACEEWGFFQVINHGIELELLEEIEKVAREFFMLPLEEKQKYP-------- 120

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913612348  82 gwTPPNTeiaVAAGGQP-DFKE------CYFMApyesdpvLEAQYPELYPPNIWPEGMTAFREEYTKMGRALHEAGLALL 154
Cdd:PLN02758 121 --MAPGT---VQGYGQAfVFSEdqkldwCNMFA-------LGVEPHFIRNPKLWPTKPARFSETLEVYSREIRELCQRLL 188

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913612348 155 RGAAHALGLAPNTFTDICEGGAHVTRILHY---------LALSPeqvntgilwgeeHTDFNLLTLLPGGRfvdptgnvap 225
Cdd:PLN02758 189 KYIAMTLGLKEDRFEEMFGEAVQAVRMNYYppcsrpdlvLGLSP------------HSDGSALTVLQQGK---------- 246

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 913612348 226 kpDDKSGLFLRTRGTpenpagvQVRGRPPEGCIVAQIGQQLEMLTGGVFVATPH 279
Cdd:PLN02758 247 --GSCVGLQILKDNT-------WVPVHPVPNALVINIGDTLEVLTNGKYKSVEH 291
PLN02904 PLN02904
oxidoreductase
 2-318 3.18e-08

oxidoreductase


Pssm-ID: 178492 [Multi-domain]  Cd Length: 357  Bit Score: 54.56  E-value: 3.18e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913612348   2 SQPSIPTVDLADLrsNDPSRIASASAAIREAFGTYGLVYVMNHGVDPNGVSRVYDEFRTLSQQPVAEKQKLARPdlwfqr 81
Cdd:PLN02904  48 STITLPVIDLSLL--HDPLLRSCVIHEIEMACKGFGFFQVINHGIPSSVVKDALDAATRFFDLPVDEKMLLVSD------ 119

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913612348  82 gwtppNTEIAVAAGgqPDFKECYFMAPYESDPVLEAQYPELYPPNIWPEGMTAFREEYTKMGRALHEAGLALLRGAAHAL 161
Cdd:PLN02904 120 -----NVHEPVRYG--TSLNHSTDRVHYWRDFIKHYSHPLSKWINLWPSNPPCYKEKVGKYAEATHVLHKQLIEAISESL 192

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913612348 162 GLAPNTFTDICEGGAHVTRILHYLALSPEQVNTGIlwgEEHTDFNLLTLLPggrfvdptgnvapkpddKSGLFLRTRGTP 241
Cdd:PLN02904 193 GLEKNYLQEEIEEGSQVMAVNCYPACPEPEIALGM---PPHSDFGSLTILL-----------------QSSQGLQIMDCN 252

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 913612348 242 ENPAGVQVrgrpPEGCIVAQIGQQLEMLTGGVFVATPHVITApgvpgwTRDSSaHFMHASANSVlfPLEKFQTPAAR 318
Cdd:PLN02904 253 KNWVCVPY----IEGALIVQLGDQVEVMSNGIYKSVVHRVTV------NKDYK-RLSFASLHSL--PLHKKISPAPE 316
PLN02912 PLN02912
oxidoreductase, 2OG-Fe(II) oxygenase family protein
 2-211 9.35e-08

oxidoreductase, 2OG-Fe(II) oxygenase family protein


Pssm-ID: 178500 [Multi-domain]  Cd Length: 348  Bit Score: 53.11  E-value: 9.35e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913612348   2 SQPSIPTVDLADLRSndPSRiASASAAIREAFGTYGLVYVMNHGVDPNGVSRVYDEFRTLSQQPVAEKQKLARPDlwfQR 81
Cdd:PLN02912  38 SGDSIPLIDLRDLHG--PNR-ADIINQFAHACSSYGFFQIKNHGVPEETIKKMMNVAREFFHQSESERVKHYSAD---TK 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913612348  82 GWTPPNTEIAVAAGGQPDFKE-----CYfmaPYEsDPVLEaqypelyppniWPEGMTAFRE---EYTKMGRALheaGLAL 153
Cdd:PLN02912 112 KTTRLSTSFNVSKEKVSNWRDflrlhCY---PIE-DFIEE-----------WPSTPISFREvtaEYATSVRAL---VLTL 173

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 913612348 154 LRGAAHALGLAPNTFTDICegGAHVTRI-LHYLALSPEQVNTGILWGeeHTDFNLLTLL 211
Cdd:PLN02912 174 LEAISESLGLEKDRVSNTL--GKHGQHMaINYYPPCPQPELTYGLPG--HKDANLITVL 228
PLN02947 PLN02947
oxidoreductase
 5-308 9.87e-08

oxidoreductase


Pssm-ID: 215510 [Multi-domain]  Cd Length: 374  Bit Score: 53.21  E-value: 9.87e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913612348   5 SIPTVDLADLR-SNDPSRIASASAAIREafgtYGLVYVMNHGVDPNGVSRVYDEFRTLSQQPVAEKQKLARPDLWFQ-RG 82
Cdd:PLN02947  66 KLPVIDLAELRgSNRPHVLATLAAACRE----YGFFQVVNHGVPSEVIGGMIDVARRFFELPLEERAKYMSADMRAPvRY 141

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913612348  83 WTPPNtEIAVAAGGQPDFKECYFMApyesdpvLEAQYPElyppniWPEGMTAFREEYTKMGRALHEAGLALLRGAAHALG 162
Cdd:PLN02947 142 GTSFN-QNKDAVFCWRDFLKLVCHP-------LSDVLPH------WPSSPADLRKVAATYAKATKRLFLELMEAILESLG 207

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913612348 163 LAPNTFTDI---CEGGAHVTRILHYLALSPEQVNTGIlwgEEHTDFNLLTLLpggrfvdptgnvapKPDDKSGLflrtrg 239
Cdd:PLN02947 208 IVKRGSDELleeFEAGSQMMVVNCYPACPEPELTLGM---PPHSDYGFLTLL--------------LQDEVEGL------ 264

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 913612348 240 tpenpaGVQVRGR-----PPEGCIVAQIGQQLEMLTGGVFVATPH-VITAPGVPgwtRDSSAHFMHASANSVLFP 308
Cdd:PLN02947 265 ------QIMHAGRwvtvePIPGSFVVNVGDHLEIFSNGRYKSVLHrVRVNSTKP---RISVASLHSLPFERVVGP 330
PLN02997 PLN02997
flavonol synthase
 2-211 1.97e-06

flavonol synthase


Pssm-ID: 178576 [Multi-domain]  Cd Length: 325  Bit Score: 49.22  E-value: 1.97e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913612348   2 SQPSIPTVDLAdlRSNDPSRIASASAAIREafgtYGLVYVMNHGVdPNGVSRvydefrtlsQQPVAEKQKLARPDlwfqr 81
Cdd:PLN02997  29 SAVDVPVVDLS--VSDEDFLVREVVKASEE----WGVFQVVNHGI-PTELMR---------QLQMVGKQFFELPE----- 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913612348  82 gwtpPNTEIAVAAGGQPDFKECYFMAPYESDpvlEAQYPELYPPNI-----WPEGMTAFRE---EYTKMGRALHEAGLAL 153
Cdd:PLN02997  88 ----AEKETVAKEEDFEGYKRNYLGGINNWD---EHLFHRLSPPSIinykyWPKNPPQYREvteEYTKHMKRLTEKILGW 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 913612348 154 LrgaAHALGLAPNTFTDICEG--GAHVTRILHYlalSPEQVNTGILWGEEHTDFNLLTLL 211
Cdd:PLN02997 161 L---SEGLGLPRETFTQSIGGetAEYVLRVNFY---PPTQDTELVIGAAAHSDMGAIALL 214
2OG-FeII_Oxy pfam03171
2OG-Fe(II) oxygenase superfamily; This family contains members of the 2-oxoglutarate (2OG) and ...
 181-299 4.96e-05

2OG-Fe(II) oxygenase superfamily; This family contains members of the 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily. This family includes the C-terminal of prolyl 4-hydroxylase alpha subunit. The holoenzyme has the activity EC:1.14.11.2 catalysing the reaction: Procollagen L-proline + 2-oxoglutarate + O2 <=> procollagen trans- 4-hydroxy-L-proline + succinate + CO2. The full enzyme consists of a alpha2 beta2 complex with the alpha subunit contributing most of the parts of the active site. The family also includes lysyl hydrolases, isopenicillin synthases and AlkB.


Pssm-ID: 397334 [Multi-domain]  Cd Length: 101  Bit Score: 41.67  E-value: 4.96e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913612348  181 ILHYLALSPEqvNTGILWGEEHTDFNLLTLLPGgrfvdptgnvapkpDDKSGLFLRTRGTpenpagvQVRGRPPEGCIVA 260
Cdd:pfam03171   6 VLNYYPPHPD--PDLTLGLGPHTDASILTILLQ--------------DDVGGLQVFKDGK-------WIDVPPLPGALVV 62

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 913612348  261 QIGQQLEMLTGGVFVATPHVITAPGvPGWTRDSSAHFMH 299
Cdd:pfam03171  63 NIGDQLELLSNGRYKSVLHRVLPVN-KGKERISIAFFLR 100
PLN02365 PLN02365
2-oxoglutarate-dependent dioxygenase
 1-213 1.50e-04

2-oxoglutarate-dependent dioxygenase


Pssm-ID: 177993 [Multi-domain]  Cd Length: 300  Bit Score: 43.24  E-value: 1.50e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913612348   1 MSQPSIPTVDLADlrsndpsrIASASAAIREAFGTYGLVYVMNHGVDPNGVSRVYDEFRTLSQQPVAEKQKlarpdlwfq 80
Cdd:PLN02365   1 MAEVNIPTIDLEE--------FPGQIEKLREACERWGCFRVVNHGVSLSLMAEMKKVVRSLFDLPDEVKRR--------- 63

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913612348  81 rgwtppNTEIAVAAGgqpdfkecyFMAPYESDPVLEAQypELYPPNIwPEGMTAF----------REEYTKMGRALHEAG 150
Cdd:PLN02365  64 ------NTDVILGSG---------YMAPSEVNPLYEAL--GLYDMAS-PQAVDTFcsqldasphqRETIKKYAKAIHDLA 125

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 913612348 151 LALLRGAAHALGLAPNtftDICEGGAHVTRILHYlALSPEQVntGILWGEEHTDFNLLTLLPG 213
Cdd:PLN02365 126 MDLARKLAESLGLVEG---DFFQGWPSQFRINKY-NFTPETV--GSSGVQIHTDSGFLTILQD 182
PLN02254 PLN02254
gibberellin 3-beta-dioxygenase
 5-323 1.91e-04

gibberellin 3-beta-dioxygenase


Pssm-ID: 215142 [Multi-domain]  Cd Length: 358  Bit Score: 43.15  E-value: 1.91e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913612348   5 SIPTVDLadlrsNDPSriasASAAIREAFGTYGLVYVMNHGVDPNGVSRVYDEFRTLSQQPVAEKQKLARpdlwfqrgwt 84
Cdd:PLN02254  56 SIPVIDL-----SDPN----ALTLIGHACETWGVFQVTNHGIPLSLLDDIESQTRRLFSLPAQRKLKAAR---------- 116

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913612348  85 PPNteiAVAAGGQPDfkecyfMAPYesdpvleaqypelYPPNIWPEGmtafreeYTKMGRALHeaglallrgaaHALGLA 164
Cdd:PLN02254 117 SPD---GVSGYGVAR------ISSF-------------FNKKMWSEG-------FTIMGSPLE-----------HARQLW 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913612348 165 PNTFTDICE----------GGAH--VTRILHYLALSPEQVN-TGILWGEEHTDFNL-LTLLPggrfvdptgnVAPKPDDK 230
Cdd:PLN02254 157 PQDHTKFCDvmeeyqkemkKLAErlMWLMLGSLGITEEDIKwAGPKSGSQGAQAALqLNSYP----------VCPDPDRA 226

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 913612348 231 SGLFLRTRGT------PENPAGVQVR-------GRPP-EGCIVAQIGQQLEMLTGGVFVATPHVITAPGVPgwTRDSSAH 296
Cdd:PLN02254 227 MGLAPHTDSSlltilyQSNTSGLQVFregvgwvTVPPvPGSLVVNVGDLLHILSNGRFPSVLHRAVVNKTR--HRISVAY 304

                        330       340
                 ....*....|....*....|....*..
gi 913612348 297 FMHASANSVLFPLEKFQTPAARSAYRP 323
Cdd:PLN02254 305 FYGPPSDVQISPLPKLVDPNHPPLYRS 331
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH