NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|985000998|gb|AMC95084|]
View 

osmoprotectant uptake system permease [Escherichia coli str. K-12 substr. MG1655]

Protein Classification

ABC transporter permease( domain architecture ID 10003065)

ABC transporter permease is the transmembrane (TM) subunit of a periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporter responsible for the translocation across the membrane of one or more from a variety of substrates including gylcine betaine, choline, and carnitine

Gene Ontology:  GO:0140359|GO:0042626|GO:0055085|GO:0016020
PubMed:  25750732|24638992|31571164|27273632|26517919|18535149|17723295
TCDB:  3.A.1

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
OpuBB COG1174
ABC-type proline/glycine betaine transport system, permease component [Amino acid transport ...
 160-383 7.21e-72

ABC-type proline/glycine betaine transport system, permease component [Amino acid transport and metabolism];


:

Pssm-ID: 440787 [Multi-domain]  Cd Length: 212  Bit Score: 223.39  E-value: 7.21e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985000998 160 LSLMKEYANRQDVFDDALAQHLTLLFGAVLPALVIGVPLGIWCYFSTARQGAIFSLLNVIQTVPSVALFGLLIAPLaalv 239
Cdd:COG1174    3 LSLIEWLADNRDGILALLLEHLLLVLLALLIALLIAVPLGILITRRRRLAGLVLGVANILQTIPSLALLALLIPLL---- 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985000998 240 tafpwlgtlgiaGTGMTPALIALVLYALLPLVRGVVVGLNQIPRDVLESARAMGMSGAQRFLHVQLPLALPVFLRSLRVV 319
Cdd:COG1174   79 ------------GIGPAPAIIALVLYALLPILRNTYTGLRSVDPAVVEAARGMGMTPWQRLWRVELPLALPVILAGIRTA 146

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 985000998 320 MVQTVGMAVIAALIGAGGFGALVFQGLLSSAIDLVLLGVIPVIVLAVLTDALFDLLIALLKVKR 383
Cdd:COG1174  147 AVQNIGTATLAALIGAGGLGDLIFDGLQLNNTALILAGAILVALLALLVDLLLALLERLLTPRG 210
 
Name Accession Description Interval E-value
OpuBB COG1174
ABC-type proline/glycine betaine transport system, permease component [Amino acid transport ...
 160-383 7.21e-72

ABC-type proline/glycine betaine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440787 [Multi-domain]  Cd Length: 212  Bit Score: 223.39  E-value: 7.21e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985000998 160 LSLMKEYANRQDVFDDALAQHLTLLFGAVLPALVIGVPLGIWCYFSTARQGAIFSLLNVIQTVPSVALFGLLIAPLaalv 239
Cdd:COG1174    3 LSLIEWLADNRDGILALLLEHLLLVLLALLIALLIAVPLGILITRRRRLAGLVLGVANILQTIPSLALLALLIPLL---- 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985000998 240 tafpwlgtlgiaGTGMTPALIALVLYALLPLVRGVVVGLNQIPRDVLESARAMGMSGAQRFLHVQLPLALPVFLRSLRVV 319
Cdd:COG1174   79 ------------GIGPAPAIIALVLYALLPILRNTYTGLRSVDPAVVEAARGMGMTPWQRLWRVELPLALPVILAGIRTA 146

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 985000998 320 MVQTVGMAVIAALIGAGGFGALVFQGLLSSAIDLVLLGVIPVIVLAVLTDALFDLLIALLKVKR 383
Cdd:COG1174  147 AVQNIGTATLAALIGAGGLGDLIFDGLQLNNTALILAGAILVALLALLVDLLLALLERLLTPRG 210
PRK10952 PRK10952
proline/glycine betaine ABC transporter permease ProW;
181-371 1.68e-20

proline/glycine betaine ABC transporter permease ProW;


Pssm-ID: 236805  Cd Length: 355  Bit Score: 91.69  E-value: 1.68e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985000998 181 LTLLFGAVLPALVIGVPLGIWCYFSTARQGAIFSLLNVIQTVPsvalfglliaplaALVTAFPWLGTLGIagtGMTPALI 260
Cdd:PRK10952 150 LALVLTALLFCIVIGLPLGIWLARSPRAAKIIRPLLDAMQTTP-------------AFVYLVPIVMLFGI---GNVPGVV 213

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985000998 261 ALVLYALLPLVRGVVVGLNQIPRDVLESARAMGMSGAQRFLHVQLPLALPVFLRSLRVVMVQTVGMAVIAALIGAGGFGA 340
Cdd:PRK10952 214 VTIIFALPPIVRLTILGINQVPADLIEASRSFGASPRQMLFKVQLPLAMPTIMAGVNQTLMLALSMVVIASMIAVGGLGQ 293

                        170       180       190
                 ....*....|....*....|....*....|.
gi 985000998 341 LVFQGLLSSAIDLVLLGVIPVIVLAVLTDAL 371
Cdd:PRK10952 294 MVLRGIGRLDMGLATVGGVGIVILAIILDRL 324
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 195-379 4.46e-16

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 75.41  E-value: 4.46e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985000998  195 GVPLGIWC--YFSTARQGAIFSLLNVIQTVPSVALFGLLIaplaalvtafpWLGTLGIAGTGMTPALIALVLYALLPLVR 272
Cdd:pfam00528   1 GIPLGIIAalRRGRRLDRLLRPLIDLLQALPSFVLAILLV-----------VIAILSILGHGILPAIILALLGWAGYARL 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985000998  273 GVVVGLNQIPRDVLESARAMGMSGAQRFLHVQLPLALPVFLRSLRVVMVQTVGMAVIAALIGAG-GFGALVFQGLLSSAI 351
Cdd:pfam00528  70 IRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWpGLGLLLIEAILGYDY 149

                         170       180
                  ....*....|....*....|....*...
gi 985000998  352 DLVLLGVIPVIVLAVLTDALFDLLIALL 379
Cdd:pfam00528 150 PEIQGPVLAAALILLLLNLLVDILQRLL 177
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 177-367 4.22e-11

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 61.53  E-value: 4.22e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985000998 177 LAQHLTLLFGAVLPALVIGVPLGIWCYFSTAR-QGAIFSLLNVIQTVPSVALfglliapLAALVTAFPWLGTLGIAGTGM 255
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGKlDRLLRRIIDLLLSLPSLVL-------GLLLVLLFGVLLGWGILPGLG 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985000998 256 TPALIALVLYALLPLVRGVVVGLNQIPRDVLESARAMGMSGAQRFLHVQLPLALPVFLRSLRVVMVQTVGMAVIAALIGA 335
Cdd:cd06261   74 LPALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGG 153

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 985000998 336 G-----GFGALVFQGLLSSAIDLVLLGVIPVIVLAVL 367
Cdd:cd06261  154 GeapgpGTGLLLIFAILFPGDLGVAAAVALILLLLSL 190
 
Name Accession Description Interval E-value
OpuBB COG1174
ABC-type proline/glycine betaine transport system, permease component [Amino acid transport ...
 160-383 7.21e-72

ABC-type proline/glycine betaine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440787 [Multi-domain]  Cd Length: 212  Bit Score: 223.39  E-value: 7.21e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985000998 160 LSLMKEYANRQDVFDDALAQHLTLLFGAVLPALVIGVPLGIWCYFSTARQGAIFSLLNVIQTVPSVALFGLLIAPLaalv 239
Cdd:COG1174    3 LSLIEWLADNRDGILALLLEHLLLVLLALLIALLIAVPLGILITRRRRLAGLVLGVANILQTIPSLALLALLIPLL---- 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985000998 240 tafpwlgtlgiaGTGMTPALIALVLYALLPLVRGVVVGLNQIPRDVLESARAMGMSGAQRFLHVQLPLALPVFLRSLRVV 319
Cdd:COG1174   79 ------------GIGPAPAIIALVLYALLPILRNTYTGLRSVDPAVVEAARGMGMTPWQRLWRVELPLALPVILAGIRTA 146

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 985000998 320 MVQTVGMAVIAALIGAGGFGALVFQGLLSSAIDLVLLGVIPVIVLAVLTDALFDLLIALLKVKR 383
Cdd:COG1174  147 AVQNIGTATLAALIGAGGLGDLIFDGLQLNNTALILAGAILVALLALLVDLLLALLERLLTPRG 210
TauC COG0600
ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion ...
 181-379 1.12e-20

ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440365 [Multi-domain]  Cd Length: 254  Bit Score: 90.21  E-value: 1.12e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985000998 181 LTLLFGAVLPALVIGVPLGIWCYFSTARQGAIFSLLNVIQTVPSVALFGLLIAplaalvtafpWLGTlgiagtGMTPALI 260
Cdd:COG0600   67 LLRVLLGFALAALLGVPLGLLLGLSRLLRRLLDPLLVFLRPIPPLALAPLLIL----------WFGI------GEASKIF 130

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985000998 261 ALVLYALLPLVRGVVVGLNQIPRDVLESARAMGMSGAQRFLHVQLPLALPVFLRSLRVVMVQTVGMAVIAALIGAG-GFG 339
Cdd:COG0600  131 VIFLGAFFPILLNTAAGVRSVDPELLELARSLGASRWQILRKVVLPAALPYIFTGLRIALGLAWIGLVVAELLGASsGLG 210

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 985000998 340 ALVFQGLLSSAIDLVLLGVIPVIVLAVLTDALFDLLIALL 379
Cdd:COG0600  211 YLILDARQLLDTDLVFAAILVIGLLGLLLDLLLRLLERRL 250
PRK10952 PRK10952
proline/glycine betaine ABC transporter permease ProW;
181-371 1.68e-20

proline/glycine betaine ABC transporter permease ProW;


Pssm-ID: 236805  Cd Length: 355  Bit Score: 91.69  E-value: 1.68e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985000998 181 LTLLFGAVLPALVIGVPLGIWCYFSTARQGAIFSLLNVIQTVPsvalfglliaplaALVTAFPWLGTLGIagtGMTPALI 260
Cdd:PRK10952 150 LALVLTALLFCIVIGLPLGIWLARSPRAAKIIRPLLDAMQTTP-------------AFVYLVPIVMLFGI---GNVPGVV 213

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985000998 261 ALVLYALLPLVRGVVVGLNQIPRDVLESARAMGMSGAQRFLHVQLPLALPVFLRSLRVVMVQTVGMAVIAALIGAGGFGA 340
Cdd:PRK10952 214 VTIIFALPPIVRLTILGINQVPADLIEASRSFGASPRQMLFKVQLPLAMPTIMAGVNQTLMLALSMVVIASMIAVGGLGQ 293

                        170       180       190
                 ....*....|....*....|....*....|.
gi 985000998 341 LVFQGLLSSAIDLVLLGVIPVIVLAVLTDAL 371
Cdd:PRK10952 294 MVLRGIGRLDMGLATVGGVGIVILAIILDRL 324
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 195-379 4.46e-16

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 75.41  E-value: 4.46e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985000998  195 GVPLGIWC--YFSTARQGAIFSLLNVIQTVPSVALFGLLIaplaalvtafpWLGTLGIAGTGMTPALIALVLYALLPLVR 272
Cdd:pfam00528   1 GIPLGIIAalRRGRRLDRLLRPLIDLLQALPSFVLAILLV-----------VIAILSILGHGILPAIILALLGWAGYARL 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985000998  273 GVVVGLNQIPRDVLESARAMGMSGAQRFLHVQLPLALPVFLRSLRVVMVQTVGMAVIAALIGAG-GFGALVFQGLLSSAI 351
Cdd:pfam00528  70 IRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWpGLGLLLIEAILGYDY 149

                         170       180
                  ....*....|....*....|....*...
gi 985000998  352 DLVLLGVIPVIVLAVLTDALFDLLIALL 379
Cdd:pfam00528 150 PEIQGPVLAAALILLLLNLLVDILQRLL 177
MetP COG2011
ABC-type methionine transport system, permease component [Amino acid transport and metabolism]; ...
 175-341 7.92e-13

ABC-type methionine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 441614  Cd Length: 220  Bit Score: 67.00  E-value: 7.92e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985000998 175 DALAQHLTLLFGAVLPALVIGVPLGIWCYfSTARQG-----AIFSLL----NVIQTVPSVALFGLLIaPLAALVTafpwl 245
Cdd:COG2011   14 QATGETLYMVGVSTLIAVLLGLPLGVLLV-LTRPGGllpnpVLYRVLgvivNIFRSIPFIILLVALI-PLTRLIV----- 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985000998 246 GTlgiaGTGMTPALIALVLYALLPLVRGVVVGLNQIPRDVLESARAMGMSGAQRFLHVQLPLALPVFLRSLRVVMVQTVG 325
Cdd:COG2011   87 GT----SIGTTAAIVPLTIAAIPFFARLVENALREVDPGVIEAAQAMGASPWQIIFKVLLPEALPSLILGLTVTLISLIG 162

                        170
                 ....*....|....*.
gi 985000998 326 MAVIAALIGAGGFGAL 341
Cdd:COG2011  163 YSAMAGAVGGGGLGDL 178
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 177-367 4.22e-11

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 61.53  E-value: 4.22e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985000998 177 LAQHLTLLFGAVLPALVIGVPLGIWCYFSTAR-QGAIFSLLNVIQTVPSVALfglliapLAALVTAFPWLGTLGIAGTGM 255
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGKlDRLLRRIIDLLLSLPSLVL-------GLLLVLLFGVLLGWGILPGLG 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985000998 256 TPALIALVLYALLPLVRGVVVGLNQIPRDVLESARAMGMSGAQRFLHVQLPLALPVFLRSLRVVMVQTVGMAVIAALIGA 335
Cdd:cd06261   74 LPALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGG 153

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 985000998 336 G-----GFGALVFQGLLSSAIDLVLLGVIPVIVLAVL 367
Cdd:cd06261  154 GeapgpGTGLLLIFAILFPGDLGVAAAVALILLLLSL 190
PRK10782 PRK10782
D-methionine ABC transporter permease MetI;
192-344 9.15e-08

D-methionine ABC transporter permease MetI;


Pssm-ID: 182726  Cd Length: 217  Bit Score: 52.43  E-value: 9.15e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985000998 192 LVIGVPLGIWCYfsTARQGAIFSLLNVIQTVPSVALFGLLIAPLAALVTAFPWlgTLGIAGT--GMTPALIALVLYALLP 269
Cdd:PRK10782  28 FVIGLPVGVLLY--VTRPGQIIANAKLYRTLSALVNIFRSIPFIILLVWMIPF--TRVIVGTsiGLQAAIVPLTVGAAPF 103

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 985000998 270 LVRGVVVGLNQIPRDVLESARAMGMSGAQRFLHVQLPLALPVFLRSLRVVMVQTVGMAVIAALIGAGGFGALVFQ 344
Cdd:PRK10782 104 IARMVENALLEIPTGLIEASRAMGATPMQIVRKVLLPEALPGLVNAATITLITLVGYSAMGGAVGAGGLGQIGYQ 178
PRK10160 PRK10160
taurine ABC transporter permease TauC;
167-365 7.30e-07

taurine ABC transporter permease TauC;


Pssm-ID: 182276  Cd Length: 275  Bit Score: 50.17  E-value: 7.30e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985000998 167 ANRQDVFDDALAQHL----TLLFGAVLPALVIGVPLGIWCYFSTARQGAIFSLLNVIQTVPsvalfglliaPLAALVTAF 242
Cdd:PRK10160  66 AGPQGFMDATLWQHLaaslTRIVLALLAAVVIGIPVGIAMGLSPTVRGILDPLIELYRPVP----------PLAYLPLMV 135

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985000998 243 PWLgtlgiaGTGMTPALIALVLYALLPLVRGVVVGLNQIPRDVLESARAMGMSGAQRFLHVQLPLALPVFLRSLRVVMVQ 322
Cdd:PRK10160 136 IWF------GIGETSKILLIYLAIFAPVAMSALAGVKSAQQVRIRAAQSLGASRAQVLWFVILPGALPEILTGLRIGLGV 209

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 985000998 323 TVGMAVIAALIGAG-GFGALVFQGLLSSAIDLVLLGVIPVIVLA 365
Cdd:PRK10160 210 GWSTLVAAELIAATrGLGFMVQSAGEFLATDVVLAGIAVIAIIA 253
PotC COG1177
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ...
 175-338 1.24e-05

ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];


Pssm-ID: 440790 [Multi-domain]  Cd Length: 262  Bit Score: 46.26  E-value: 1.24e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985000998 175 DALAQHLTLLFGAVLPALVIGVPLGIWCYFSTAR-QGAIFSLLNVIQTVPSVAL-FGLLIaplaalvtafpWLGTLGIAG 252
Cdd:COG1177   61 DALLNSLLIALLSTLLATVLGTPAALALARYRFRgRRLLLALLLLPLVVPGIVLgVALLL-----------LFSALGLSG 129

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985000998 253 tGMTPALIALVLYALLPLVRGVVVGLNQIPRDVLESARAMGMSGAQRFLHVQLPLALPVFLRSLRVVMVQTVGMAVIAAL 332
Cdd:COG1177  130 -GLWGLILAHVVFTLPFVVLVVLARLQGFDPSLEEAARDLGASPWQTFRRVTLPLIAPGILAGALLAFTLSFDEFVITLF 208


                 ....*.
gi 985000998 333 IGAGGF 338
Cdd:COG1177  209 LAGPGV 214
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
175-368 4.06e-05

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 45.54  E-value: 4.06e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985000998 175 DALAQHLTLLFGAVLPALVIGVPLGiwcYFSTARQGAIFSLLNVIQTVPsVALFGLLIAplAALVTAFPWLGTLGIAGTG 254
Cdd:COG1178  338 RALLNSLLLALLAALLAVLLALLLA---YLVRRRRGRLARLLDRLAMLP-YAVPGIVLG--LGLLLLFNRPLPLLLYGTL 411

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985000998 255 mtPALIALVLYALLPL-VRGVVVGLNQIPRDVLESARAMGMSGAQRFLHVQLPLALPVFLRSLRVVMVQTVGMAVIAALI 333
Cdd:COG1178  412 --AILVLAYVVRFLPFaLRSLEAALAQIDPSLEEAARSLGASPLRTLRRVTLPLLRPGLLAAALLVFVTSMKELSATLLL 489

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 985000998 334 GAGGF---GALVFQgLLSS---------AIDLVLLGVIPVIVLAVLT 368
Cdd:COG1178  490 RPPGFetlAVLIYQ-LASSgrygeaaalALLLVLVSLLPVLLLERLL 535
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
230-336 7.23e-05

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 44.77  E-value: 7.23e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985000998 230 LLIAPLA--ALVTAFPWLGTLGIAGT-----------------GMTPALIALVLYaLLPLV-RGVVVGLNQIPRDVLESA 289
Cdd:COG1178   95 LLLLPLAlpPYVVALAWIALFGPNGLlntllralfgleppdiyGLGGIILVLVLF-NYPYVyLLLRAALRSIDASLEEAA 173

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 985000998 290 RAMGMSGAQRFLHVQLPLALPVFLRSLRVVMVQTVGMAVIAALIGAG 336
Cdd:COG1178  174 RSLGASPWRAFRRVTLPLLRPAIAAGALLVFLLCLADFGTPLVLGGG 220
HisM COG0765
ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; ...
 245-316 5.53e-04

ABC-type amino acid transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440528 [Multi-domain]  Cd Length: 218  Bit Score: 40.83  E-value: 5.53e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 985000998 245 LGTLGIAGTGMTPALIALVLYA---LLPLVRGvvvGLNQIPRDVLESARAMGMSGAQRFLHVQLPLALPVFLRSL 316
Cdd:COG0765   78 LPLLGIDLSPFVAAVIALTLNSaayLAEIVRA---GIQSVPKGQWEAARALGLSRWQTMRRIILPQALRIILPPL 149
ssuC PRK11365
aliphatic sulfonate ABC transporter permease SsuC;
194-375 6.88e-04

aliphatic sulfonate ABC transporter permease SsuC;


Pssm-ID: 183100  Cd Length: 263  Bit Score: 41.07  E-value: 6.88e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985000998 194 IGVPLGIWCYFSTARQGAIFSLLNVIQTVPSVALFGLLIAplaalvtafpWLGTlgiagtGMTPALIALVLYALLPLVRG 273
Cdd:PRK11365  79 LGLILGLISGLSRWGERLLDTSIQMLRNVPHLALIPLVIL----------WFGI------DESAKIFLVALGTLFPIYIN 142

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985000998 274 VVVGLNQIPRDVLESARAMGMSGAQRFLHVQLPLALPVFLRSLRVVMVQTVGMAVIAALIGA-GGFGALVFQGLLSSAID 352
Cdd:PRK11365 143 TWHGIRNIDRGLVEMARSYGLSGIPLFIHVILPGALPSIMVGVRFALGLMWLTLIVAETISAnSGIGYLAMNAREFLQTD 222

                        170       180
                 ....*....|....*....|...
gi 985000998 353 LVLLGVIPVIVLAVLTDALFDLL 375
Cdd:PRK11365 223 VVVVAIILYALLGKLADVSAQLL 245
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 166-379 1.84e-03

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 39.67  E-value: 1.84e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985000998 166 YANRQDVFD---DALAQHLTLLFGAVLPALVIGVPLGIWcyfSTARQGAIFSLLNVIQTVPSVALFGLLIAPLAALVTAF 242
Cdd:COG0601   81 FVYGRPVSDliaERLPVTLELALLALLLALLIGIPLGIL---AALRRGSWLDRLITVLALLGISIPSFWLGLLLILLFAV 157

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985000998 243 pWLGTLGIAGTGMTPALIALVLYAL-LPLVRGVVVGLNQIPR-------DVLES-----ARAMGMSGAQRFLHVQLPLAL 309
Cdd:COG0601  158 -KLGWLPVSGRVSPWEDFLDALRHLiLPALTLALGSLAGIARltrssmlEVLGQdyvrtARAKGLSERRVLLRHALRNAL 236

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 985000998 310 pvflrslrVVMVQTVGMAVIAALIGA---------GGFGALVFQGLLSSAIDLVLLGVIPVIVLAVLTDALFDLLIALL 379
Cdd:COG0601  237 --------IPVVTVLGLQLGGLLGGAvvvetvfswPGLGRLLVDAILNRDYPVVQGIVLLIAVLVVLVNLLVDLLYALL 307
potB PRK09497
spermidine/putrescine ABC transporter membrane protein; Reviewed
 258-336 9.72e-03

spermidine/putrescine ABC transporter membrane protein; Reviewed


Pssm-ID: 181910  Cd Length: 285  Bit Score: 37.36  E-value: 9.72e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985000998 258 ALIALVLYALLP-LVRGVVVGLNQIPRDVLESARAMGMSGAQRFLHVQLPLALPVFLRSLRVVMVQTVGMAVIAALIGAG 336
Cdd:PRK09497 152 AVIIGLVYILLPfMVLPLYSSIEKLDKPLLEAARDLGANKLQTFIRIIIPLTMPGIIAGCLLVLLPAMGMFYVSDLLGGA 231
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH