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Conserved domains on  [gi|985003559|gb|AMC97645|]
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preprotein translocase subunit YajC [Escherichia coli str. K-12 substr. MG1655]

Protein Classification

preprotein translocase subunit YajC( domain architecture ID 10012470)

preprotein translocase subunit YajC forms a complex with SecD and SecF and plays a role in stabilizing and regulating secretion through the SecYEG transmembrane complex via SecA

Gene Ontology:  GO:0015031|GO:0005886
PubMed:  20801097

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
yajC PRK05585
preprotein translocase subunit YajC; Validated
 3-110 1.83e-52

preprotein translocase subunit YajC; Validated


:

Pssm-ID: 235518  Cd Length: 106  Bit Score: 160.06  E-value: 1.83e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985003559   3 FFISDAVAATGAPaQGSPMSLILMLVVFGLIFYFMILRPQQKRTKEHKKLMDSIAKGDEVLTNGGLVGRVTKVAENgYIA 82
Cdd:PRK05585   1 FFISNAYAQAAAP-AGSGLSSLLPLVVFFAIFYFLIIRPQQKRQKEHKKMLSSLAKGDEVVTNGGIIGKVTKVSED-FVI 78

                         90       100
                 ....*....|....*....|....*...
gi 985003559  83 IALNDTTEVVIKRDFVAAVLPKGTMKAL 110
Cdd:PRK05585  79 IELNDDTEIKIQKSAIAAVLPKGTLKSL 106
 
Name Accession Description Interval E-value
yajC PRK05585
preprotein translocase subunit YajC; Validated
 3-110 1.83e-52

preprotein translocase subunit YajC; Validated


Pssm-ID: 235518  Cd Length: 106  Bit Score: 160.06  E-value: 1.83e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985003559   3 FFISDAVAATGAPaQGSPMSLILMLVVFGLIFYFMILRPQQKRTKEHKKLMDSIAKGDEVLTNGGLVGRVTKVAENgYIA 82
Cdd:PRK05585   1 FFISNAYAQAAAP-AGSGLSSLLPLVVFFAIFYFLIIRPQQKRQKEHKKMLSSLAKGDEVVTNGGIIGKVTKVSED-FVI 78

                         90       100
                 ....*....|....*....|....*...
gi 985003559  83 IALNDTTEVVIKRDFVAAVLPKGTMKAL 110
Cdd:PRK05585  79 IELNDDTEIKIQKSAIAAVLPKGTLKSL 106
YajC COG1862
Protein translocase subunit YajC [Intracellular trafficking, secretion, and vesicular ...
 11-110 1.15e-37

Protein translocase subunit YajC [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 441467  Cd Length: 102  Bit Score: 122.21  E-value: 1.15e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985003559  11 ATGAPAQGSPMSLILMLVVFGLIFYFMILRPQQKRTKEHKKLMDSIAKGDEVLTNGGLVGRVTKVAENgYIAIALNDTTE 90
Cdd:COG1862    4 ALAQAGGGSGLMSLLPLVLIFVIFYFLMIRPQQKRQKEHKEMLSSLKKGDEVVTIGGIHGTVVKVDDD-TVTLEIADGVK 82

                         90       100
                 ....*....|....*....|
gi 985003559  91 VVIKRDFVAAVLPKGTMKAL 110
Cdd:COG1862   83 VKVERSAIARVLPKGTAKAA 102
yajC TIGR00739
preprotein translocase, YajC subunit; While this protein is part of the preprotein translocase ...
 19-103 7.51e-35

preprotein translocase, YajC subunit; While this protein is part of the preprotein translocase in Escherichia coli, it is not essential for viability or protein secretion. The N-terminus region contains a predicted membrane-spanning region followed by a region consisting almost entirely of residues with charged (acidic, basic, or zwitterionic) side chains. This small protein is about 100 residues in length, and is restricted to bacteria; however, this protein is absent from some lineages, including spirochetes and Mycoplasmas. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273243  Cd Length: 84  Bit Score: 114.71  E-value: 7.51e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985003559   19 SPMSLILMLVVFGLIFYFMILRPQQKRTKEHKKLMDSIAKGDEVLTNGGLVGRVTKVAENGyIAIALNDTTEVVIKRDFV 98
Cdd:TIGR00739   1 SFLTTLLPLVLIFLIFYFLIIRPQRKRRKAHKKLIESLKKGDKVLTIGGIIGTVTKIAENT-IVIELNDNTEITFSKNAI 79


                  ....*
gi 985003559   99 AAVLP 103
Cdd:TIGR00739  80 VEVLP 84
YajC pfam02699
Preprotein translocase subunit; See.
 22-100 2.83e-26

Preprotein translocase subunit; See.


Pssm-ID: 460655  Cd Length: 78  Bit Score: 92.85  E-value: 2.83e-26
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 985003559   22 SLILMLVVFGLIFYFMILRPQQKRTKEHKKLMDSIAKGDEVLTNGGLVGRVTKVAENgYIAIALNDTTEVVIKRDFVAA 100
Cdd:pfam02699   1 SSLLPLVLIFVIFYFLMIRPQQKRQKEHQEMLDSLKKGDEVVTIGGIHGKVVKVDDD-EVTLEIAAGVKIKVERSAIAE 78
 
Name Accession Description Interval E-value
yajC PRK05585
preprotein translocase subunit YajC; Validated
 3-110 1.83e-52

preprotein translocase subunit YajC; Validated


Pssm-ID: 235518  Cd Length: 106  Bit Score: 160.06  E-value: 1.83e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985003559   3 FFISDAVAATGAPaQGSPMSLILMLVVFGLIFYFMILRPQQKRTKEHKKLMDSIAKGDEVLTNGGLVGRVTKVAENgYIA 82
Cdd:PRK05585   1 FFISNAYAQAAAP-AGSGLSSLLPLVVFFAIFYFLIIRPQQKRQKEHKKMLSSLAKGDEVVTNGGIIGKVTKVSED-FVI 78

                         90       100
                 ....*....|....*....|....*...
gi 985003559  83 IALNDTTEVVIKRDFVAAVLPKGTMKAL 110
Cdd:PRK05585  79 IELNDDTEIKIQKSAIAAVLPKGTLKSL 106
YajC COG1862
Protein translocase subunit YajC [Intracellular trafficking, secretion, and vesicular ...
 11-110 1.15e-37

Protein translocase subunit YajC [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 441467  Cd Length: 102  Bit Score: 122.21  E-value: 1.15e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985003559  11 ATGAPAQGSPMSLILMLVVFGLIFYFMILRPQQKRTKEHKKLMDSIAKGDEVLTNGGLVGRVTKVAENgYIAIALNDTTE 90
Cdd:COG1862    4 ALAQAGGGSGLMSLLPLVLIFVIFYFLMIRPQQKRQKEHKEMLSSLKKGDEVVTIGGIHGTVVKVDDD-TVTLEIADGVK 82

                         90       100
                 ....*....|....*....|
gi 985003559  91 VVIKRDFVAAVLPKGTMKAL 110
Cdd:COG1862   83 VKVERSAIARVLPKGTAKAA 102
yajC TIGR00739
preprotein translocase, YajC subunit; While this protein is part of the preprotein translocase ...
 19-103 7.51e-35

preprotein translocase, YajC subunit; While this protein is part of the preprotein translocase in Escherichia coli, it is not essential for viability or protein secretion. The N-terminus region contains a predicted membrane-spanning region followed by a region consisting almost entirely of residues with charged (acidic, basic, or zwitterionic) side chains. This small protein is about 100 residues in length, and is restricted to bacteria; however, this protein is absent from some lineages, including spirochetes and Mycoplasmas. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273243  Cd Length: 84  Bit Score: 114.71  E-value: 7.51e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985003559   19 SPMSLILMLVVFGLIFYFMILRPQQKRTKEHKKLMDSIAKGDEVLTNGGLVGRVTKVAENGyIAIALNDTTEVVIKRDFV 98
Cdd:TIGR00739   1 SFLTTLLPLVLIFLIFYFLIIRPQRKRRKAHKKLIESLKKGDKVLTIGGIIGTVTKIAENT-IVIELNDNTEITFSKNAI 79


                  ....*
gi 985003559   99 AAVLP 103
Cdd:TIGR00739  80 VEVLP 84
YajC pfam02699
Preprotein translocase subunit; See.
 22-100 2.83e-26

Preprotein translocase subunit; See.


Pssm-ID: 460655  Cd Length: 78  Bit Score: 92.85  E-value: 2.83e-26
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 985003559   22 SLILMLVVFGLIFYFMILRPQQKRTKEHKKLMDSIAKGDEVLTNGGLVGRVTKVAENgYIAIALNDTTEVVIKRDFVAA 100
Cdd:pfam02699   1 SSLLPLVLIFVIFYFLMIRPQQKRQKEHQEMLDSLKKGDEVVTIGGIHGKVVKVDDD-EVTLEIAAGVKIKVERSAIAE 78
yajC PRK06531
preprotein translocase subunit YajC; Validated
 20-75 1.40e-08

preprotein translocase subunit YajC; Validated


Pssm-ID: 235822  Cd Length: 113  Bit Score: 48.64  E-value: 1.40e-08
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 985003559  20 PMSLILMLVVF-GLIFYFMilRPQQKRTKEHKKLMDSIAKGDEVLTNGGLVGRVTKV 75
Cdd:PRK06531   2 GIPTIIMFVVMlGLIFFMQ--RQQKKQAQERQNQLNAIQKGDEVVTIGGLYGTVDEV 56
PRK13922 PRK13922
rod shape-determining protein MreC; Provisional
 54-102 5.96e-04

rod shape-determining protein MreC; Provisional


Pssm-ID: 237560  Cd Length: 276  Bit Score: 37.27  E-value: 5.96e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 985003559  54 DSIAKGDEVLTNGGLVGRVTKVAENGYIAIALNDTTE---VVIKRDFVAAVL 102
Cdd:PRK13922 144 DGVKKGMPVIDPGGLVGRVIEVSPNTSRVLLLTDPNSrvpVQVGRNGIRGIL 195
MreC pfam04085
rod shape-determining protein MreC; MreC (murein formation C) is involved in the rod shape ...
 54-78 8.25e-04

rod shape-determining protein MreC; MreC (murein formation C) is involved in the rod shape determination in E. coli, and more generally in cell shape determination of bacteria whether or not they are rod-shaped.


Pssm-ID: 461164  Cd Length: 148  Bit Score: 36.30  E-value: 8.25e-04
                          10        20
                  ....*....|....*....|....*
gi 985003559   54 DSIAKGDEVLTNGGLVGRVTKVAEN 78
Cdd:pfam04085  21 DGIKKGMPVITGNGLVGRVTEVSPN 45
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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