|
Name |
Accession |
Description |
Interval |
E-value |
| PRK01259 |
PRK01259 |
ribose-phosphate diphosphokinase; |
4-314 |
0e+00 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 234929 [Multi-domain] Cd Length: 309 Bit Score: 603.65 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 4 MKLFAGNATPELAQRIANRLYTSLGDAAVGRFSDGEVSVQINENVRGGDIFIIQSTCAPTNDNLMELVVMVDALRRASAG 83
Cdd:PRK01259 1 MKLFAGNANPELAEKIAKYLGIPLGKASVGRFSDGEISVEINENVRGKDVFIIQSTCAPTNDNLMELLIMIDALKRASAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 84 RITAVIPYFGYARQDRRVRSaRVPITAKVVADFLSSVGVDRVLTVDLHAEQIQGFFDVPVDNVFGSPILLEDMLQLNLDN 163
Cdd:PRK01259 81 RITAVIPYFGYARQDRKARS-RVPITAKLVANLLETAGADRVLTMDLHADQIQGFFDIPVDNLYGSPILLEDIKQKNLEN 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 164 PIVVSPDIGGVVRARAIAKLLNdTDMAIIDKRRPRANVSQVMHIIGDVAGRDCVLVDDMIDTGGTLCKAAEALKERGAKR 243
Cdd:PRK01259 160 LVVVSPDVGGVVRARALAKRLD-ADLAIIDKRRPRANVSEVMNIIGDVEGRDCILVDDMIDTAGTLCKAAEALKERGAKS 238
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 985004999 244 VFAYATHPIFSGNAANNLRNSVIDEVVVCDTIPLSDEIKSLPNVRTLTLSGMLAEAIRRISNEESISAMFE 314
Cdd:PRK01259 239 VYAYATHPVLSGGAIERIENSVIDELVVTDSIPLSEEAKKCDKIRVLSVAPLLAEAIRRISNEESVSSLFD 309
|
|
| PrsA |
COG0462 |
Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism]; ... |
1-314 |
0e+00 |
|
Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism]; Phosphoribosylpyrophosphate synthetase is part of the Pathway/BioSystem: Histidine biosynthesis, Purine biosynthesis
Pssm-ID: 440230 [Multi-domain] Cd Length: 311 Bit Score: 540.03 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 1 MPDMKLFAGNATPELAQRIANRLYTSLGDAAVGRFSDGEVSVQINENVRGGDIFIIQSTCAPTNDNLMELVVMVDALRRA 80
Cdd:COG0462 1 MKDLKIFSGNANPELAEEIAEYLGVPLGKAEVRRFSDGEIYVRIEESVRGRDVFVIQSTSPPVNDNLMELLIMIDALKRA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 81 SAGRITAVIPYFGYARQDRRVRsARVPITAKVVADFLSSVGVDRVLTVDLHAEQIQGFFDVPVDNVFGSPILLEDMLQLN 160
Cdd:COG0462 81 SARRITAVIPYYGYARQDRKFR-PREPITAKLVADLLEAAGADRVLTVDLHAPQIQGFFDIPVDHLYAAPLLADYIKSKD 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 161 LDNPIVVSPDIGGVVRARAIAKLLnDTDMAIIDKRRPRANVSQVMHIIGDVAGRDCVLVDDMIDTGGTLCKAAEALKERG 240
Cdd:COG0462 160 LEDLVVVSPDVGGVKRARAFAKRL-GAPLAIIDKRRPGANEVEVMNIIGDVEGKTCIIVDDMIDTGGTLVEAAEALKEAG 238
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 985004999 241 AKRVFAYATHPIFSGNAANNLRNSVIDEVVVCDTIPLSDEiKSLPNVRTLTLSGMLAEAIRRISNEESISAMFE 314
Cdd:COG0462 239 AKSVYAAATHGVLSGPAVERLENSPIDELVVTDTIPLPEE-KRCDKIKVLSVAPLLAEAIRRIHEGESVSSLFD 311
|
|
| ribP_PPkin |
TIGR01251 |
ribose-phosphate pyrophosphokinase; Alternate name: phosphoribosylpyrophosphate synthetase In ... |
4-314 |
6.48e-160 |
|
ribose-phosphate pyrophosphokinase; Alternate name: phosphoribosylpyrophosphate synthetase In some systems, close homologs lacking enzymatic activity exist and perform regulatory functions. The model is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 273523 [Multi-domain] Cd Length: 308 Bit Score: 448.27 E-value: 6.48e-160
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 4 MKLFAGNATPELAQRIANRLYTSLGDAAVGRFSDGEVSVQINENVRGGDIFII-QSTCAPTNDNLMELVVMVDALRRASA 82
Cdd:TIGR01251 1 MKIFSGSSNQELAQKVAKNLGLPLGDVEVKRFPDGELYVRINESVRGKDVFIIqQSTSAPVNDNLMELLIMIDALKRASA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 83 GRITAVIPYFGYARQDRRVRSaRVPITAKVVADFLSSVGVDRVLTVDLHAEQIQGFFDVPVDNVFGSPILLEDMLQLNLD 162
Cdd:TIGR01251 81 KSITAVIPYYGYARQDKKFKS-REPISAKLVANLLETAGADRVLTVDLHSPQIQGFFDVPVDNLYASPVLAEYLKKKILD 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 163 NPIVVSPDIGGVVRARAIAKLLNdTDMAIIDKRRP-RANVSQVMHIIGDVAGRDCVLVDDMIDTGGTLCKAAEALKERGA 241
Cdd:TIGR01251 160 NPVVVSPDAGGVERAKKVADALG-CPLAIIDKRRIsATNEVEVMNLVGDVEGKDVVIVDDIIDTGGTIAKAAEILKSAGA 238
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 985004999 242 KRVFAYATHPIFSGNAANNLRNSVIDEVVVCDTIPLSdeiKSLPNVRTLTLSGMLAEAIRRISNEESISAMFE 314
Cdd:TIGR01251 239 KRVIAAATHGVFSGPAIERIANAGVEEVIVTNTIPHE---KHKPKVSVISVAPLIAEAIRRIHNNESVSSLFD 308
|
|
| Pribosyltran_N |
pfam13793 |
N-terminal domain of ribose phosphate pyrophosphokinase; This family is frequently found ... |
4-121 |
2.25e-71 |
|
N-terminal domain of ribose phosphate pyrophosphokinase; This family is frequently found N-terminal to the Pribosyltran, pfam00156.
Pssm-ID: 433483 [Multi-domain] Cd Length: 117 Bit Score: 216.52 E-value: 2.25e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 4 MKLFAGNATPELAQRIANRLYTSLGDAAVGRFSDGEVSVQINENVRGGDIFIIQSTCAPTNDNLMELVVMVDALRRASAG 83
Cdd:pfam13793 1 LKIFSGNSNPELAEKIAKRLGIPLGKATVSRFSDGEIYVRIEESVRGKDVFIIQSTCPPVNDNLMELLIMIDALKRASAK 80
|
90 100 110
....*....|....*....|....*....|....*...
gi 985004999 84 RITAVIPYFGYARQDRRVRSaRVPITAKVVADFLSSVG 121
Cdd:pfam13793 81 RITAVIPYFGYARQDRKDKP-REPITAKLVADLLEAAG 117
|
|
| PRTases_typeI |
cd06223 |
Phosphoribosyl transferase (PRT)-type I domain; Phosphoribosyl transferase (PRT) domain. The ... |
149-274 |
1.16e-27 |
|
Phosphoribosyl transferase (PRT)-type I domain; Phosphoribosyl transferase (PRT) domain. The type I PRTases are identified by a conserved PRPP binding motif which features two adjacent acidic residues surrounded by one or more hydrophobic residue. PRTases catalyze the displacement of the alpha-1'-pyrophosphate of 5-phosphoribosyl-alpha1-pyrophosphate (PRPP) by a nitrogen-containing nucleophile. The reaction products are an alpha-1 substituted ribose-5'-phosphate and a free pyrophosphate (PP). PRPP, an activated form of ribose-5-phosphate, is a key metabolite connecting nucleotide synthesis and salvage pathways. The type I PRTase family includes a range of diverse phosphoribosyl transferase enzymes and regulatory proteins of the nucleotide synthesis and salvage pathways, including adenine phosphoribosyltransferase EC:2.4.2.7., hypoxanthine-guanine-xanthine phosphoribosyltransferase, hypoxanthine phosphoribosyltransferase EC:2.4.2.8., ribose-phosphate pyrophosphokinase EC:2.7.6.1., amidophosphoribosyltransferase EC:2.4.2.14., orotate phosphoribosyltransferase EC:2.4.2.10., uracil phosphoribosyltransferase EC:2.4.2.9., and xanthine-guanine phosphoribosyltransferase EC:2.4.2.22.
Pssm-ID: 206754 [Multi-domain] Cd Length: 130 Bit Score: 104.40 E-value: 1.16e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 149 SPILLEDMLQLNLDNPIVVSPDIGGVVRARAIAKLLNdTDMAIIDKRRPRANVSQVM------HIIGDVAGRDCVLVDDM 222
Cdd:cd06223 2 GRLLAEEIREDLLEPDVVVGILRGGLPLAAALARALG-LPLAFIRKERKGPGRTPSEpyglelPLGGDVKGKRVLLVDDV 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 985004999 223 IDTGGTLCKAAEALKERGAKRVFAYATHPIFSGNAanNLRNSVIDEVVVCDT 274
Cdd:cd06223 81 IATGGTLLAAIELLKEAGAKVVGVAVLLDKPEGGA--RELASPGDPVYSLFT 130
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK01259 |
PRK01259 |
ribose-phosphate diphosphokinase; |
4-314 |
0e+00 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 234929 [Multi-domain] Cd Length: 309 Bit Score: 603.65 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 4 MKLFAGNATPELAQRIANRLYTSLGDAAVGRFSDGEVSVQINENVRGGDIFIIQSTCAPTNDNLMELVVMVDALRRASAG 83
Cdd:PRK01259 1 MKLFAGNANPELAEKIAKYLGIPLGKASVGRFSDGEISVEINENVRGKDVFIIQSTCAPTNDNLMELLIMIDALKRASAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 84 RITAVIPYFGYARQDRRVRSaRVPITAKVVADFLSSVGVDRVLTVDLHAEQIQGFFDVPVDNVFGSPILLEDMLQLNLDN 163
Cdd:PRK01259 81 RITAVIPYFGYARQDRKARS-RVPITAKLVANLLETAGADRVLTMDLHADQIQGFFDIPVDNLYGSPILLEDIKQKNLEN 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 164 PIVVSPDIGGVVRARAIAKLLNdTDMAIIDKRRPRANVSQVMHIIGDVAGRDCVLVDDMIDTGGTLCKAAEALKERGAKR 243
Cdd:PRK01259 160 LVVVSPDVGGVVRARALAKRLD-ADLAIIDKRRPRANVSEVMNIIGDVEGRDCILVDDMIDTAGTLCKAAEALKERGAKS 238
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 985004999 244 VFAYATHPIFSGNAANNLRNSVIDEVVVCDTIPLSDEIKSLPNVRTLTLSGMLAEAIRRISNEESISAMFE 314
Cdd:PRK01259 239 VYAYATHPVLSGGAIERIENSVIDELVVTDSIPLSEEAKKCDKIRVLSVAPLLAEAIRRISNEESVSSLFD 309
|
|
| PrsA |
COG0462 |
Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism]; ... |
1-314 |
0e+00 |
|
Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism]; Phosphoribosylpyrophosphate synthetase is part of the Pathway/BioSystem: Histidine biosynthesis, Purine biosynthesis
Pssm-ID: 440230 [Multi-domain] Cd Length: 311 Bit Score: 540.03 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 1 MPDMKLFAGNATPELAQRIANRLYTSLGDAAVGRFSDGEVSVQINENVRGGDIFIIQSTCAPTNDNLMELVVMVDALRRA 80
Cdd:COG0462 1 MKDLKIFSGNANPELAEEIAEYLGVPLGKAEVRRFSDGEIYVRIEESVRGRDVFVIQSTSPPVNDNLMELLIMIDALKRA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 81 SAGRITAVIPYFGYARQDRRVRsARVPITAKVVADFLSSVGVDRVLTVDLHAEQIQGFFDVPVDNVFGSPILLEDMLQLN 160
Cdd:COG0462 81 SARRITAVIPYYGYARQDRKFR-PREPITAKLVADLLEAAGADRVLTVDLHAPQIQGFFDIPVDHLYAAPLLADYIKSKD 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 161 LDNPIVVSPDIGGVVRARAIAKLLnDTDMAIIDKRRPRANVSQVMHIIGDVAGRDCVLVDDMIDTGGTLCKAAEALKERG 240
Cdd:COG0462 160 LEDLVVVSPDVGGVKRARAFAKRL-GAPLAIIDKRRPGANEVEVMNIIGDVEGKTCIIVDDMIDTGGTLVEAAEALKEAG 238
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 985004999 241 AKRVFAYATHPIFSGNAANNLRNSVIDEVVVCDTIPLSDEiKSLPNVRTLTLSGMLAEAIRRISNEESISAMFE 314
Cdd:COG0462 239 AKSVYAAATHGVLSGPAVERLENSPIDELVVTDTIPLPEE-KRCDKIKVLSVAPLLAEAIRRIHEGESVSSLFD 311
|
|
| ribP_PPkin |
TIGR01251 |
ribose-phosphate pyrophosphokinase; Alternate name: phosphoribosylpyrophosphate synthetase In ... |
4-314 |
6.48e-160 |
|
ribose-phosphate pyrophosphokinase; Alternate name: phosphoribosylpyrophosphate synthetase In some systems, close homologs lacking enzymatic activity exist and perform regulatory functions. The model is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 273523 [Multi-domain] Cd Length: 308 Bit Score: 448.27 E-value: 6.48e-160
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 4 MKLFAGNATPELAQRIANRLYTSLGDAAVGRFSDGEVSVQINENVRGGDIFII-QSTCAPTNDNLMELVVMVDALRRASA 82
Cdd:TIGR01251 1 MKIFSGSSNQELAQKVAKNLGLPLGDVEVKRFPDGELYVRINESVRGKDVFIIqQSTSAPVNDNLMELLIMIDALKRASA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 83 GRITAVIPYFGYARQDRRVRSaRVPITAKVVADFLSSVGVDRVLTVDLHAEQIQGFFDVPVDNVFGSPILLEDMLQLNLD 162
Cdd:TIGR01251 81 KSITAVIPYYGYARQDKKFKS-REPISAKLVANLLETAGADRVLTVDLHSPQIQGFFDVPVDNLYASPVLAEYLKKKILD 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 163 NPIVVSPDIGGVVRARAIAKLLNdTDMAIIDKRRP-RANVSQVMHIIGDVAGRDCVLVDDMIDTGGTLCKAAEALKERGA 241
Cdd:TIGR01251 160 NPVVVSPDAGGVERAKKVADALG-CPLAIIDKRRIsATNEVEVMNLVGDVEGKDVVIVDDIIDTGGTIAKAAEILKSAGA 238
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 985004999 242 KRVFAYATHPIFSGNAANNLRNSVIDEVVVCDTIPLSdeiKSLPNVRTLTLSGMLAEAIRRISNEESISAMFE 314
Cdd:TIGR01251 239 KRVIAAATHGVFSGPAIERIANAGVEEVIVTNTIPHE---KHKPKVSVISVAPLIAEAIRRIHNNESVSSLFD 308
|
|
| PRK04923 |
PRK04923 |
ribose-phosphate diphosphokinase; |
2-313 |
1.59e-158 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 179893 [Multi-domain] Cd Length: 319 Bit Score: 445.14 E-value: 1.59e-158
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 2 PDMKLFAGNATPELAQRIANRLYTSLGDAAVGRFSDGEVSVQINENVRGGDIFIIQSTCAPTNDNLMELVVMVDALRRAS 81
Cdd:PRK04923 5 RNLLVFSGNANKPLAQSICKELGVRMGKALVTRFSDGEVQVEIEESVRRQEVFVIQPTCAPSAENLMELLVLIDALKRAS 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 82 AGRITAVIPYFGYARQDRRVRSARVPITAKVVADFLSSVGVDRVLTVDLHAEQIQGFFDVPVDNVFGSPILLEDML-QLN 160
Cdd:PRK04923 85 AASVTAVIPYFGYSRQDRRMRSSRVPITAKVAAKMISAMGADRVLTVDLHADQIQGFFDVPVDNVYASPLLLADIWrAYG 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 161 LDNPIVVSPDIGGVVRARAIAKLLNDTDMAIIDKRRPRANVSQVMHIIGDVAGRDCVLVDDMIDTGGTLCKAAEALKERG 240
Cdd:PRK04923 165 TDNLIVVSPDVGGVVRARAVAKRLDDADLAIIDKRRPRANVATVMNIIGDVQGKTCVLVDDLVDTAGTLCAAAAALKQRG 244
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 985004999 241 AKRVFAYATHPIFSGNAANNLRNSVIDEVVVCDTIPLSDEIKSLPNVRTLTLSGMLAEAIRRISNEESISAMF 313
Cdd:PRK04923 245 ALKVVAYITHPVLSGPAVDNINNSQLDELVVTDTIPLSEAARACAKIRQLSVAELLAETIRRIAFGESVSSLY 317
|
|
| PLN02369 |
PLN02369 |
ribose-phosphate pyrophosphokinase |
13-313 |
3.10e-134 |
|
ribose-phosphate pyrophosphokinase
Pssm-ID: 215209 [Multi-domain] Cd Length: 302 Bit Score: 382.89 E-value: 3.10e-134
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 13 PELAQRIANRLYTSLGDAAVGRFSDGEVSVQINENVRGGDIFIIQSTCAPTNDNLMELVVMVDALRRASAGRITAVIPYF 92
Cdd:PLN02369 1 PALSQEIACYLGLELGKITIKRFADGEIYVQLQESVRGCDVFLVQPTCPPANENLMELLIMIDACRRASAKRITAVIPYF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 93 GYARQDRRvRSARVPITAKVVADFLSSVGVDRVLTVDLHAEQIQGFFDVPVDNVFGSPILLEDMLQLNL--DNPIVVSPD 170
Cdd:PLN02369 81 GYARADRK-TQGRESIAAKLVANLITEAGADRVLACDLHSGQSMGYFDIPVDHVYGQPVILDYLASKTIssPDLVVVSPD 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 171 IGGVVRARAIAKLLNDTDMAIIDKRRPRANVSQVMHIIGDVAGRDCVLVDDMIDTGGTLCKAAEALKERGAKRVFAYATH 250
Cdd:PLN02369 160 VGGVARARAFAKKLSDAPLAIVDKRRQGHNVAEVMNLIGDVKGKVAIMVDDMIDTAGTITKGAALLHQEGAREVYACATH 239
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 985004999 251 PIFSGNAANNLRNSVIDEVVVCDTIPLSDEiKSLPNVRTLTLSGMLAEAIRRISNEESISAMF 313
Cdd:PLN02369 240 AVFSPPAIERLSSGLFQEVIVTNTIPVSEK-NYFPQLTVLSVANLLGETIWRVHDDCSVSSIF 301
|
|
| PRK02812 |
PRK02812 |
ribose-phosphate pyrophosphokinase; Provisional |
4-313 |
9.77e-134 |
|
ribose-phosphate pyrophosphokinase; Provisional
Pssm-ID: 235072 [Multi-domain] Cd Length: 330 Bit Score: 382.94 E-value: 9.77e-134
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 4 MKLFAGNATPELAQRIANRLYTSLGDAAVGRFSDGEVSVQINENVRGGDIFIIQSTCAPTNDNLMELVVMVDALRRASAG 83
Cdd:PRK02812 22 LRLFSGSSNPALAQEVARYLGMDLGPMIRKRFADGELYVQIQESIRGCDVYLIQPTCAPVNDHLMELLIMVDACRRASAR 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 84 RITAVIPYFGYARQDRRVrSARVPITAKVVADFLSSVGVDRVLTVDLHAEQIQGFFDVPVDNVFGSPILLEDMLQLNLDN 163
Cdd:PRK02812 102 QITAVIPYYGYARADRKT-AGRESITAKLVANLITKAGADRVLAMDLHSAQIQGYFDIPCDHVYGSPVLLDYLASKNLED 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 164 PIVVSPDIGGVVRARAIAKLLNDTDMAIIDKRRPRANVSQVMHIIGDVAGRDCVLVDDMIDTGGTLCKAAEALKERGAKR 243
Cdd:PRK02812 181 IVVVSPDVGGVARARAFAKKLNDAPLAIIDKRRQAHNVAEVLNVIGDVKGKTAILVDDMIDTGGTICEGARLLRKEGAKQ 260
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 244 VFAYATHPIFSGNAANNLRNSVIDEVVVCDTIPLSDEiKSLPNVRTLTLSGMLAEAIRRISNEESISAMF 313
Cdd:PRK02812 261 VYACATHAVFSPPAIERLSSGLFEEVIVTNTIPVPEE-RRFPQLKVLSVANMLGEAIWRIHEESSVSSMF 329
|
|
| PRK02269 |
PRK02269 |
ribose-phosphate diphosphokinase; |
3-314 |
1.43e-128 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 167353 [Multi-domain] Cd Length: 320 Bit Score: 369.51 E-value: 1.43e-128
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 3 DMKLFAGNATPELAQRIANRLYTSLGDAAVGRFSDGEVSVQINENVRGGDIFIIQSTCAPTNDNLMELVVMVDALRRASA 82
Cdd:PRK02269 5 DLKLFALSSNKELAEKVAQEIGIELGKSSVRQFSDGEIQVNIEESIRGHHVFILQSTSSPVNDNLMEILIMVDALKRASA 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 83 GRITAVIPYFGYARQDRRVRSaRVPITAKVVADFLSSVGVDRVLTVDLHAEQIQGFFDVPVDNVFGSPILLE--DMLQLN 160
Cdd:PRK02269 85 ESINVVMPYYGYARQDRKARS-REPITSKLVANMLEVAGVDRLLTVDLHAAQIQGFFDIPVDHLMGAPLIADyfDRRGLV 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 161 LDNPIVVSPDIGGVVRARAIAKLLNdTDMAIIDKRRP--RANVSQVMHIIGDVAGRDCVLVDDMIDTGGTLCKAAEALKE 238
Cdd:PRK02269 164 GDDVVVVSPDHGGVTRARKLAQFLK-TPIAIIDKRRSvdKMNTSEVMNIIGNVKGKKCILIDDMIDTAGTICHAADALAE 242
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 985004999 239 RGAKRVFAYATHPIFSGNAANNLRNSVIDEVVVCDTIPLSDEiKSLPNVRTLTLSGMLAEAIRRISNEESISAMFE 314
Cdd:PRK02269 243 AGATEVYASCTHPVLSGPALDNIQKSAIEKLVVLDTIYLPEE-RLIDKIEQISIADLLGEAIIRIHEKRPLSPLFE 317
|
|
| PTZ00145 |
PTZ00145 |
phosphoribosylpyrophosphate synthetase; Provisional |
1-313 |
1.56e-122 |
|
phosphoribosylpyrophosphate synthetase; Provisional
Pssm-ID: 240290 [Multi-domain] Cd Length: 439 Bit Score: 358.42 E-value: 1.56e-122
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 1 MPDMKLFAGNATPELAQRIANRLYTSLGDAAVGRFSDGEVSVQINENVRGGDIFIIQSTCAPTNDNLMELVVMVDALRRA 80
Cdd:PTZ00145 117 MENAILFSGSSNPLLSKNIADHLGTILGRVHLKRFADGEVSMQFLESIRGKDVYIIQPTCPPVNENLIELLLMISTCRRA 196
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 81 SAGRITAVIPYFGYARQDRRVrSARVPITAKVVADFLSSVGVDRVLTVDLHAEQIQGFFD--VPVDNVFGSPILLEDMLQ 158
Cdd:PTZ00145 197 SAKKITAVIPYYGYARQDRKL-SSRVPISAADVARMIEAMGVDRVVAIDLHSGQIQGFFGprVPVDNLEAQLIGLDYFTK 275
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 159 LNLDNPIVVSPDIGGVVRARA-----IAKLLNDTDMAIIDKRRPRANVSQVMHIIGDVAGRDCVLVDDMIDTGGTLCKAA 233
Cdd:PTZ00145 276 KDLYKPVIVSPDAGGVYRARKfqdglNHRGISDCGIAMLIKQRTKPNEIEKMDLVGNVYDSDVIIVDDMIDTSGTLCEAA 355
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 234 EALKERGAKRVFAYATHPIFSGNAANNLRNSVIDEVVVCDTIPLSDEIKSLPNVRTLTLSGMLAEAIRRISNEESISAMF 313
Cdd:PTZ00145 356 KQLKKHGARRVFAFATHGLFSGPAIERIEASPLEEVVVTDTVKSNKNIDSCKKITKLSVSVLVADAIRRIHQKESLNDLF 435
|
|
| PRK03092 |
PRK03092 |
ribose-phosphate diphosphokinase; |
15-314 |
5.00e-114 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 179535 [Multi-domain] Cd Length: 304 Bit Score: 331.91 E-value: 5.00e-114
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 15 LAQRIANRLYTSLGDAAVGRFSDGEVSVQINENVRGGDIFIIQSTCAPTNDNLMELVVMVDALRRASAGRITAVIPYFGY 94
Cdd:PRK03092 1 LAEEVAKELGVEVTPTTAYDFANGEIYVRFEESVRGCDAFVLQSHTAPINKWLMEQLIMIDALKRASAKRITVVLPFYPY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 95 ARQDRRVRsARVPITAKVVADFLSSVGVDRVLTVDLHAEQIQGFFDVPVDNVFGSPILLEDMLQ-LNLDNPIVVSPDIGG 173
Cdd:PRK03092 81 ARQDKKHR-GREPISARLVADLFKTAGADRIMTVDLHTAQIQGFFDGPVDHLFAMPLLADYVRDkYDLDNVTVVSPDAGR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 174 VVRARAIAKLLNDTDMAIIDKRRP--RANVSQVMHIIGDVAGRDCVLVDDMIDTGGTLCKAAEALKERGAKRVFAYATHP 251
Cdd:PRK03092 160 VRVAEQWADRLGGAPLAFIHKTRDptVPNQVVANRVVGDVEGRTCVLVDDMIDTGGTIAGAVRALKEAGAKDVIIAATHG 239
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 985004999 252 IFSGNAANNLRNSVIDEVVVCDTIPLSDEiKSLPNVRTLTLSGMLAEAIRRISNEESISAMFE 314
Cdd:PRK03092 240 VLSGPAAERLKNCGAREVVVTDTLPIPEE-KRFDKLTVLSIAPLLARAIREVFEDGSVTSLFD 301
|
|
| PRK02458 |
PRK02458 |
ribose-phosphate pyrophosphokinase; Provisional |
2-315 |
2.63e-103 |
|
ribose-phosphate pyrophosphokinase; Provisional
Pssm-ID: 235039 [Multi-domain] Cd Length: 323 Bit Score: 305.13 E-value: 2.63e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 2 PDMKLFAGNATPELAQRIANRLYTSLGDAAVGRFSDGEVSVQINENVRGGDIFIIQSTCAPTNDNLMELVVMVDALRRAS 81
Cdd:PRK02458 8 KQIKLFSLNSNLEIAEKIAQAAGVPLGKLSSRQFSDGEIMINIEESVRGDDIYIIQSTSFPVNDHLWELLIMIDACKRAS 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 82 AGRITAVIPYFGYARQDrRVRSARVPITAKVVADFLSSVGVDRVLTVDLHAEQIQGFFDVPVDNVFGSPILLEDMLQLNL 161
Cdd:PRK02458 88 ANTVNVVLPYFGYARQD-RIAKPREPITAKLVANMLVKAGVDRVLTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCKKGL 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 162 --DNPIVVSPDIGGVVRARAIAKLLnDTDMAIIDKRRPRANVSQvMHIIGDVAGRDCVLVDDMIDTGGTLCKAAEALKER 239
Cdd:PRK02458 167 sgSDVVVVSPKNSGIKRARSLAEYL-DAPIAIIDYAQDDSEREE-GYIIGDVAGKKAILIDDILNTGKTFAEAAKIVERE 244
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 985004999 240 GAKRVFAYATHPIFSGNAANNLRNSVIDEVVVCDTIPLSDEIKSlpNVRTLTLSGMLAEAIRRISNEESISAMFEH 315
Cdd:PRK02458 245 GATEIYAVASHGLFAGGAAEVLENAPIKEILVTDSVATKERVPK--NVTYLSASELIADAIIRIHERKPLSPLFAY 318
|
|
| PRK00553 |
PRK00553 |
ribose-phosphate pyrophosphokinase; Provisional |
6-314 |
1.44e-100 |
|
ribose-phosphate pyrophosphokinase; Provisional
Pssm-ID: 179062 [Multi-domain] Cd Length: 332 Bit Score: 298.75 E-value: 1.44e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 6 LFAGNATPELAQRIANRLYTSLGDAAVGRFSDGEVSVQINENVRGGDIFIIQSTCAPTNDNLMELVVMVDALRRASAGRI 85
Cdd:PRK00553 12 IFSLSKAKKLVDSICRKLSMKPGEIVIQKFADGETYIRFDESVRNKDVVIFQSTCSPVNDSLMELLIAIDALKRGSAKSI 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 86 TAVIPYFGYARQDRRVRsARVPITAKVVADFLSSVGVDRVLTVDLHAEQIQGFFDVPVDNVFGSPILLEDMLQLN-LDNP 164
Cdd:PRK00553 92 TAILPYYGYARQDRKTA-GREPITSKLVADLLTKAGVTRVTLTDIHSDQTQGFFDIPVDILRTYHVFLSRVLELLgKKDL 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 165 IVVSPDIGGVVRARAIAKLLNdTDMAIIDKRRPRANVSQVMHIIGDVAGRDCVLVDDMIDTGGTLCKAAEALKERGAKRV 244
Cdd:PRK00553 171 VVVSPDYGGVKRARLIAESLE-LPLAIIDKRRPKHNVAESINVLGEVKNKNCLIVDDMIDTGGTVIAAAKLLKKQKAKKV 249
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 985004999 245 FAYATHPIFSGNAANNL----RNSVIDEVVVCDTIPLSdEIKSLPNVRTLTLSGMLAEAIRRISNEESISAMFE 314
Cdd:PRK00553 250 CVMATHGLFNKNAIQLFdeafKKKLIDKLFVSNSIPQT-KFEKKPQFKVVDLAHLYEEVLLCYANGGSISAIYT 322
|
|
| PRK00934 |
PRK00934 |
ribose-phosphate pyrophosphokinase; Provisional |
5-276 |
7.37e-74 |
|
ribose-phosphate pyrophosphokinase; Provisional
Pssm-ID: 234868 [Multi-domain] Cd Length: 285 Bit Score: 228.64 E-value: 7.37e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 5 KLFAGNATPELAQRIANRLYTSLGDAAVGRFSDGEVSVQINENVRGGDIFIIQSTcAPTNDNLMELVVMVDALRRASAGR 84
Cdd:PRK00934 1 MIIGGSASQLLASEVARLLNTELALVETKRFPDGELYVRILGEIDGEDVVIISTT-YPQDENLVELLLLIDALRDEGAKS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 85 ITAVIPYFGYARQDRRVRSARvPITAKVVADFLSSVGvDRVLTVDLHAEQIQGFFDVPVDNVFGSPiLLEDMLQLNLDNP 164
Cdd:PRK00934 80 ITLVIPYLGYARQDKRFKPGE-PISARAIAKIISAYY-DRIITINIHEPSILEFFPIPFINLDAAP-LIAEYIGDKLDDP 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 165 IVVSPDIGGVVRARAIAKLLNdTDMAIIDKRR--PRANVSQVMHIigDVAGRDCVLVDDMIDTGGTLCKAAEALKERGAK 242
Cdd:PRK00934 157 LVLAPDKGALELAKEAAEILG-CEYDYLEKTRisPTEVEIAPKNL--DVKGKDVLIVDDIISTGGTMATAIKILKEQGAK 233
|
250 260 270
....*....|....*....|....*....|....
gi 985004999 243 RVFAYATHPIFSGNAANNLRNSVIDEVVVCDTIP 276
Cdd:PRK00934 234 KVYVACVHPVLVGDAILKLYNAGVDEIIVTDTLE 267
|
|
| Pribosyltran_N |
pfam13793 |
N-terminal domain of ribose phosphate pyrophosphokinase; This family is frequently found ... |
4-121 |
2.25e-71 |
|
N-terminal domain of ribose phosphate pyrophosphokinase; This family is frequently found N-terminal to the Pribosyltran, pfam00156.
Pssm-ID: 433483 [Multi-domain] Cd Length: 117 Bit Score: 216.52 E-value: 2.25e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 4 MKLFAGNATPELAQRIANRLYTSLGDAAVGRFSDGEVSVQINENVRGGDIFIIQSTCAPTNDNLMELVVMVDALRRASAG 83
Cdd:pfam13793 1 LKIFSGNSNPELAEKIAKRLGIPLGKATVSRFSDGEIYVRIEESVRGKDVFIIQSTCPPVNDNLMELLIMIDALKRASAK 80
|
90 100 110
....*....|....*....|....*....|....*...
gi 985004999 84 RITAVIPYFGYARQDRRVRSaRVPITAKVVADFLSSVG 121
Cdd:pfam13793 81 RITAVIPYFGYARQDRKDKP-REPITAKLVADLLEAAG 117
|
|
| PRK06827 |
PRK06827 |
phosphoribosylpyrophosphate synthetase; Provisional |
34-310 |
3.29e-48 |
|
phosphoribosylpyrophosphate synthetase; Provisional
Pssm-ID: 180714 [Multi-domain] Cd Length: 382 Bit Score: 165.51 E-value: 3.29e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 34 RFSDGEVSVQINENVRGGDIFIIQSTC---------------APtNDNLMELVVMVDALRrASAGRITAVIPYFGYARQD 98
Cdd:PRK06827 61 RFSNGEAKGEILESVRGKDIYILQDVGnysvtynmfgeknhmSP-DDHFQDLKRTIDAIR-GKARRITVIMPFLYESRQH 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 99 RRvrSARVPITAKVVADFLSSVGVDRVLTVDLHAEQIQ------GFfdvpvDNVFGS----PILLEDMLQLNLDNP--IV 166
Cdd:PRK06827 139 KR--KGRESLDCALALQELEELGVDNIITFDAHDPRIEnaiplmGF-----ENLYPSyqiiKALLKNEKDLEIDKDhlMV 211
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 167 VSPDIGGVVRARAIAKLLNdTDMAIIDKRRPRANVSQ-----VMH-IIG-DVAGRDCVLVDDMIDTGGTLCKAAEALKER 239
Cdd:PRK06827 212 ISPDTGAMDRAKYYASVLG-VDLGLFYKRRDYSRVVNgrnpiVAHeFLGrDVEGKDVLIVDDMIASGGSMIDAAKELKSR 290
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 985004999 240 GAKRVFAYATHPIFsgnaANNLR-------NSVIDEVVVCDTIPLSDEIKSLPNVRTLTLSGMLAEAIRRISNEESIS 310
Cdd:PRK06827 291 GAKKIIVAATFGFF----TNGLEkfdkayeEGYFDRIIGTNLVYHPEELLSKPWYIEVDMSKLIARIIDALNHDVSLS 364
|
|
| PRK07199 |
PRK07199 |
ribose-phosphate diphosphokinase; |
7-302 |
5.48e-46 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 235960 [Multi-domain] Cd Length: 301 Bit Score: 157.41 E-value: 5.48e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 7 FAGNAtpELAQRIANRLYTSLGDAAVGRFSDGEVSVQINENVRGGDIFIIQSTCAPtNDNLMELVVMVDALRRASAGRIT 86
Cdd:PRK07199 8 LPGNE--AAAGRLAAALGVEVGRIELHRFPDGESYVRLDSPVAGRTVVLVCSLDRP-DEKLLPLLFAAEAARELGARRVG 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 87 AVIPYFGYARQDRRVRSARVpITAKVVADFLSSVgVDRVLTVDLHAEQI---QGFFDVPVDNVFGSPiLLEDMLQLNLDN 163
Cdd:PRK07199 85 LVAPYLAYMRQDIAFHPGEA-ISQRHFARLLSGS-FDRLVTVDPHLHRYpslSEVYPIPAVVLSAAP-AIAAWIRAHVPR 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 164 PIVVSPDIGGVVRARAIAKLLnDTDMAIIDK-RRPRANVSQVMHIIGDVAGRDCVLVDDMIDTGGTLCKAAEALKERGAK 242
Cdd:PRK07199 162 PLLIGPDEESEQWVAAVAERA-GAPHAVLRKtRHGDRDVEISLPDAAPWAGRTPVLVDDIVSTGRTLIEAARQLRAAGAA 240
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 985004999 243 RVFAYATHPIFSGNAANNLRNSVIDEVVVCDTIP-LSDEIkslpnvrtlTLSGMLAEAIRR 302
Cdd:PRK07199 241 SPDCVVVHALFAGDAYSALAAAGIARVVSTDTVPhPSNAI---------SLAPLLAEALRR 292
|
|
| Pribosyl_synth |
pfam14572 |
Phosphoribosyl synthetase-associated domain; This family includes several examples of enzymes ... |
205-313 |
4.81e-30 |
|
Phosphoribosyl synthetase-associated domain; This family includes several examples of enzymes from class EC:2.7.6.1, phosphoribosyl-pyrophosphate transferase.
Pssm-ID: 434046 Cd Length: 184 Bit Score: 112.60 E-value: 4.81e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 205 MHIIGDVAGRDCVLVDDMIDTGGTLCKAAEALKERGAKRVFAYATHPIFSGNAANNLRNSVIDEVVVCDTIPLSDEIKSL 284
Cdd:pfam14572 75 MTVVGDVGGRIAIIVDDMIDDVDSFVAAAELLKERGAYKIYVMATHGLLSSDAPRLLEASPIDEVVVTNTIPHEIQKMQC 154
|
90 100
....*....|....*....|....*....
gi 985004999 285 PNVRTLTLSGMLAEAIRRISNEESISAMF 313
Cdd:pfam14572 155 HKIKTIDISQLIAEAIRRIHNGESMSYLF 183
|
|
| PRTases_typeI |
cd06223 |
Phosphoribosyl transferase (PRT)-type I domain; Phosphoribosyl transferase (PRT) domain. The ... |
149-274 |
1.16e-27 |
|
Phosphoribosyl transferase (PRT)-type I domain; Phosphoribosyl transferase (PRT) domain. The type I PRTases are identified by a conserved PRPP binding motif which features two adjacent acidic residues surrounded by one or more hydrophobic residue. PRTases catalyze the displacement of the alpha-1'-pyrophosphate of 5-phosphoribosyl-alpha1-pyrophosphate (PRPP) by a nitrogen-containing nucleophile. The reaction products are an alpha-1 substituted ribose-5'-phosphate and a free pyrophosphate (PP). PRPP, an activated form of ribose-5-phosphate, is a key metabolite connecting nucleotide synthesis and salvage pathways. The type I PRTase family includes a range of diverse phosphoribosyl transferase enzymes and regulatory proteins of the nucleotide synthesis and salvage pathways, including adenine phosphoribosyltransferase EC:2.4.2.7., hypoxanthine-guanine-xanthine phosphoribosyltransferase, hypoxanthine phosphoribosyltransferase EC:2.4.2.8., ribose-phosphate pyrophosphokinase EC:2.7.6.1., amidophosphoribosyltransferase EC:2.4.2.14., orotate phosphoribosyltransferase EC:2.4.2.10., uracil phosphoribosyltransferase EC:2.4.2.9., and xanthine-guanine phosphoribosyltransferase EC:2.4.2.22.
Pssm-ID: 206754 [Multi-domain] Cd Length: 130 Bit Score: 104.40 E-value: 1.16e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 149 SPILLEDMLQLNLDNPIVVSPDIGGVVRARAIAKLLNdTDMAIIDKRRPRANVSQVM------HIIGDVAGRDCVLVDDM 222
Cdd:cd06223 2 GRLLAEEIREDLLEPDVVVGILRGGLPLAAALARALG-LPLAFIRKERKGPGRTPSEpyglelPLGGDVKGKRVLLVDDV 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 985004999 223 IDTGGTLCKAAEALKERGAKRVFAYATHPIFSGNAanNLRNSVIDEVVVCDT 274
Cdd:cd06223 81 IATGGTLLAAIELLKEAGAKVVGVAVLLDKPEGGA--RELASPGDPVYSLFT 130
|
|
| PLN02297 |
PLN02297 |
ribose-phosphate pyrophosphokinase |
6-300 |
2.68e-23 |
|
ribose-phosphate pyrophosphokinase
Pssm-ID: 177934 [Multi-domain] Cd Length: 326 Bit Score: 97.84 E-value: 2.68e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 6 LFAGNATPELAQRIANR-LYTSLGDAAVGRFSDGEVSVQIN--ENVRGGDIFIIQSTCAPtnDNLMELVVMVDALRRASA 82
Cdd:PLN02297 19 LFYCEETEELARKIAAEsDAIELGSINWRKFPDGFPNLFINnaHGIRGQHVAFLASFSSP--AVIFEQLSVIYALPKLFV 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 83 GRITAVIPYFGYARQDRRVRSARVPiTAKVVADFLSSV-----GVDRVLTVDLHAEQIQGFFDvpvDNVF-----GSPIL 152
Cdd:PLN02297 97 ASFTLVLPFFPTGTSERVEREGDVA-TAFTLARILSNIpisrgGPTSLVIFDIHALQERFYFG---DNVLpcfesGIPLL 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 153 LEDMLQL-NLDNPIVVSPDIGGVVRaraIAKLLNDTDMAIIDKRRpRANVSQVMHIIGDVAGRDCVLVDDMIDTGGTLCK 231
Cdd:PLN02297 173 KKRLQQLpDSDNIVIAFPDDGAWKR---FHKQFEHFPMVVCTKVR-EGDKRIVRIKEGNPAGRHVVIVDDLVQSGGTLIE 248
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 985004999 232 AAEALKERGAKRVFAYATHPIFSG------NAANNLRNSVIDEVVVCDTIPLS-DEIKSLPNVRTLTLSGMLAEAI 300
Cdd:PLN02297 249 CQKVLAAHGAAKVSAYVTHGVFPNeswerfTHDNGGPEAGFAYFWITDSCPQTvKAVRGKAPFEVLSLAGSIADAL 324
|
|
| Pribosyltran |
pfam00156 |
Phosphoribosyl transferase domain; This family includes a range of diverse phosphoribosyl ... |
158-244 |
8.31e-16 |
|
Phosphoribosyl transferase domain; This family includes a range of diverse phosphoribosyl transferase enzymes. This family includes: Adenine phosphoribosyl-transferase EC:2.4.2.7. Hypoxanthine-guanine-xanthine phosphoribosyl-transferase. Hypoxanthine phosphoribosyl-transferase EC:2.4.2.8. Ribose-phosphate pyrophosphokinase i EC:2.7.6.1. Amidophosphoribosyltransferase EC:2.4.2.14. Orotate phosphoribosyl-transferase EC:2.4.2.10. Uracil phosphoribosyl-transferase EC:2.4.2.9. Xanthine-guanine phosphoribosyl-transferase EC:2.4.2.22. In Arabidopsis, At the very N-terminus of this domain is the P-Loop NTPase domain.
Pssm-ID: 425489 [Multi-domain] Cd Length: 150 Bit Score: 73.17 E-value: 8.31e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 158 QLNLDNPIVVSPDIGGVVRARAIAKLLnDTDMAIIDKRRPRANVSQVM---HIIGDVAGRDCVLVDDMIDTGGTLCKAAE 234
Cdd:pfam00156 25 DYGGKPDVVVGILRGGLPFAGILARRL-DVPLAFVRKVSYNPDTSEVMktsSALPDLKGKTVLIVDDILDTGGTLLKVLE 103
|
90
....*....|
gi 985004999 235 ALKERGAKRV 244
Cdd:pfam00156 104 LLKNVGPKEV 113
|
|
| HptA |
COG0634 |
Hypoxanthine-guanine phosphoribosyltransferase [Nucleotide transport and metabolism]; ... |
210-244 |
7.06e-08 |
|
Hypoxanthine-guanine phosphoribosyltransferase [Nucleotide transport and metabolism]; Hypoxanthine-guanine phosphoribosyltransferase is part of the Pathway/BioSystem: Purine salvage
Pssm-ID: 440399 Cd Length: 176 Bit Score: 51.57 E-value: 7.06e-08
10 20 30
....*....|....*....|....*....|....*
gi 985004999 210 DVAGRDCVLVDDMIDTGGTLCKAAEALKERGAKRV 244
Cdd:COG0634 88 DIEGRDVLIVEDIIDTGLTLSYLLELLKSRGPASV 122
|
|
| PRK02277 |
PRK02277 |
orotate phosphoribosyltransferase-like protein; Provisional |
155-244 |
1.49e-07 |
|
orotate phosphoribosyltransferase-like protein; Provisional
Pssm-ID: 235023 [Multi-domain] Cd Length: 200 Bit Score: 51.02 E-value: 1.49e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 155 DMLQLNLDNP-IVVSPDIGGVVRARAIAKLLnDTDMAII--------DKRRPRANVSQVMhiiGDVAGRDCVLVDDMIDT 225
Cdd:PRK02277 77 DMLEKEDEEVdVVVGIAKSGVPLATLVADEL-GKDLAIYhpkkwdhgEGEKKTGSFSRNF---ASVEGKRCVIVDDVITS 152
|
90
....*....|....*....
gi 985004999 226 GGTLCKAAEALKERGAKRV 244
Cdd:PRK02277 153 GTTMKETIEYLKEHGGKPV 171
|
|
| upp |
PRK00129 |
uracil phosphoribosyltransferase; Reviewed |
210-246 |
8.71e-07 |
|
uracil phosphoribosyltransferase; Reviewed
Pssm-ID: 234653 Cd Length: 209 Bit Score: 48.93 E-value: 8.71e-07
10 20 30
....*....|....*....|....*....|....*..
gi 985004999 210 DVAGRDCVLVDDMIDTGGTLCKAAEALKERGAKRVFA 246
Cdd:PRK00129 121 DIDERTVIVVDPMLATGGSAIAAIDLLKKRGAKNIKV 157
|
|
| Hpt1 |
COG2236 |
Hypoxanthine phosphoribosyltransferase [Coenzyme transport and metabolism]; Hypoxanthine ... |
169-244 |
1.19e-06 |
|
Hypoxanthine phosphoribosyltransferase [Coenzyme transport and metabolism]; Hypoxanthine phosphoribosyltransferase is part of the Pathway/BioSystem: Purine salvage
Pssm-ID: 441837 [Multi-domain] Cd Length: 153 Bit Score: 47.53 E-value: 1.19e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985004999 169 PDI------GGVVRARAIAKLLNDTDMAII--------DKRRPRANVSQvmHIIGDVAGRDCVLVDDMIDTGGTLCKAAE 234
Cdd:COG2236 32 PDVivaiarGGLVPARILADALGVPDLASIrvssytgtAKRLEEPVVKG--PLDEDLAGKRVLIVDDVADTGRTLEAVRD 109
|
90
....*....|
gi 985004999 235 ALKERGAKRV 244
Cdd:COG2236 110 LLKEAGPAEV 119
|
|
| PLN02238 |
PLN02238 |
hypoxanthine phosphoribosyltransferase |
210-244 |
8.95e-05 |
|
hypoxanthine phosphoribosyltransferase
Pssm-ID: 215132 Cd Length: 189 Bit Score: 42.72 E-value: 8.95e-05
10 20 30
....*....|....*....|....*....|....*
gi 985004999 210 DVAGRDCVLVDDMIDTGGTLCKAAEALKERGAKRV 244
Cdd:PLN02238 94 DVKGKHVLLVEDIVDTGNTLSALVAHLEAKGAASV 128
|
|
| PyrE |
COG0461 |
Orotate phosphoribosyltransferase [Nucleotide transport and metabolism]; Orotate ... |
165-242 |
5.09e-04 |
|
Orotate phosphoribosyltransferase [Nucleotide transport and metabolism]; Orotate phosphoribosyltransferase is part of the Pathway/BioSystem: Pyrimidine biosynthesis
Pssm-ID: 440229 Cd Length: 201 Bit Score: 40.52 E-value: 5.09e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 985004999 165 IVVSPDIGGVVRARAIAKLLNdTDMAIIdkRRPRANVSQVMHIIGDV-AGRDCVLVDDMIDTGGTLCKAAEALKERGAK 242
Cdd:COG0461 66 AVAGPATGGIPLAAAVARALG-LPAIFV--RKEAKDHGTGGQIEGGLlPGERVLVVEDVITTGGSVLEAVEALREAGAE 141
|
|
| PRK02304 |
PRK02304 |
adenine phosphoribosyltransferase; Provisional |
205-242 |
3.34e-03 |
|
adenine phosphoribosyltransferase; Provisional
Pssm-ID: 235028 Cd Length: 175 Bit Score: 37.75 E-value: 3.34e-03
10 20 30
....*....|....*....|....*....|....*...
gi 985004999 205 MHIIGDVAGRDCVLVDDMIDTGGTLCKAAEALKERGAK 242
Cdd:PRK02304 106 IHKDAIKPGDRVLIVDDLLATGGTLEAAIKLLERLGAE 143
|
|
| PRK09162 |
PRK09162 |
hypoxanthine-guanine phosphoribosyltransferase; Provisional |
194-246 |
3.54e-03 |
|
hypoxanthine-guanine phosphoribosyltransferase; Provisional
Pssm-ID: 181675 Cd Length: 181 Bit Score: 37.92 E-value: 3.54e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 985004999 194 KRRPRANVsqvmhiigdvAGRDCVLVDDMIDTGGTLCKAAEALKERGAKRVFA 246
Cdd:PRK09162 88 KVKPRESL----------KGRTVLVVDDILDEGHTLAAIRDRCLEMGAAEVYS 130
|
|
| PLN02293 |
PLN02293 |
adenine phosphoribosyltransferase |
204-244 |
4.19e-03 |
|
adenine phosphoribosyltransferase
Pssm-ID: 177930 Cd Length: 187 Bit Score: 37.73 E-value: 4.19e-03
10 20 30 40
....*....|....*....|....*....|....*....|.
gi 985004999 204 VMHIIGDVAGRDCVLVDDMIDTGGTLCKAAEALKERGAKRV 244
Cdd:PLN02293 116 EMHVGAVEPGERALVIDDLIATGGTLCAAINLLERAGAEVV 156
|
|
| PTZ00149 |
PTZ00149 |
hypoxanthine phosphoribosyltransferase; Provisional |
205-244 |
7.87e-03 |
|
hypoxanthine phosphoribosyltransferase; Provisional
Pssm-ID: 240293 Cd Length: 241 Bit Score: 37.05 E-value: 7.87e-03
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 985004999 205 MHIIGD----VAGRDCVLVDDMIDTGGTLCKAAEALKERGAKRV 244
Cdd:PTZ00149 138 LEIVSDdlscLKDKHVLIVEDIIDTGNTLVKFCEYLKKFEPKTI 181
|
|
| |
