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Conserved domains on  [gi|1039015507|gb|ANM65048|]
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SKP1 interacting partner 4 [Arabidopsis thaliana]

Protein Classification

F-box/kelch-repeat protein( domain architecture ID 17778853)

F-box/kelch-repeat protein may be a component of SCF(ASK-cullin-F-box) E3 ubiquitin ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins

CATH:  1.20.1280.50|2.120.10.80
Gene Ontology:  GO:0006511|GO:0019005|GO:0005515|GO:0016567
PubMed:  10603472|31898225|11178263|31442578|24959344|10581972
SCOP:  4001927|3000448

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
NanM super family cl34543
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
88-313 1.51e-19

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


The actual alignment was detected with superfamily member COG3055:

Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 87.13  E-value: 1.51e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039015507  88 LHMLNPfsSRRSWKRINDYPyIPMREGMGFAVLGKRLFVLGGCGWLED---ATDEIYCYDAAMNTWfDVVPPLSTKRCYF 164
Cdd:COG3055    40 FEVYDP--ATNTWSELAPLP-GPPRHHAAAVAQDGKLYVFGGFTGANPsstPLNDVYVYDPATNTW-TKLAPMPTPRGGA 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039015507 165 ACETLDGKIIAIGGLGLNPNAKRTWdIYDPLTRTCKSCSDvniVPEMEDS----FVMDGRIYIRGGVGGsstavySASSG 240
Cdd:COG3055   116 TALLLDGKIYVVGGWDDGGNVAWVE-VYDPATGTWTQLAP---LPTPRDHlaaaVLPDGKILVIGGRNG------SGFSN 185

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1039015507 241 IWERMDDDMASGWRGPAVVVAGDLYVLDQTFGAKLTMWCKD--TRMWIHIGKLSQLvmKQPCRLVSIGNSIFVIG 313
Cdd:COG3055   186 TWTTLAPLPTARAGHAAAVLGGKILVFGGESGFSDEVEAYDpaTNTWTALGELPTP--RHGHAAVLTDGKVYVIG 258
F-box_AtAFR-like cd22152
F-box domain found in Arabidopsis thaliana protein ATTENUATED FAR-RED RESPONSE (AtAFR) and ...
 21-65 2.38e-17

F-box domain found in Arabidopsis thaliana protein ATTENUATED FAR-RED RESPONSE (AtAFR) and similar proteins; AtAFR, also called SKP1-interacting partner 29 (AtSKIP29), or F-box protein AFR, is a component of SCF (SKP1/ASK-cullin-F-box protein) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins. It is part of the phyA-mediated signaling transduction pathway leading to the regulation of gene expression and hypocotyl elongation in response to red and far-red light exposure. This subfamily also includes many other Arabidopsis thaliana SKP1-interacting partner proteins. The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression.


:

Pssm-ID: 438923  Cd Length: 45  Bit Score: 74.91  E-value: 2.38e-17
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 1039015507  21 LISGVPDDISKSCLARVPREYHMAMKCVSRRWRDFVCSDEMCDYR 65
Cdd:cd22152     1 LIPGLPDDIALQCLARVPRSSHPSLSLVSKSWRSLLSSPELFRVR 45
 
Name Accession Description Interval E-value
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
88-313 1.51e-19

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 87.13  E-value: 1.51e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039015507  88 LHMLNPfsSRRSWKRINDYPyIPMREGMGFAVLGKRLFVLGGCGWLED---ATDEIYCYDAAMNTWfDVVPPLSTKRCYF 164
Cdd:COG3055    40 FEVYDP--ATNTWSELAPLP-GPPRHHAAAVAQDGKLYVFGGFTGANPsstPLNDVYVYDPATNTW-TKLAPMPTPRGGA 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039015507 165 ACETLDGKIIAIGGLGLNPNAKRTWdIYDPLTRTCKSCSDvniVPEMEDS----FVMDGRIYIRGGVGGsstavySASSG 240
Cdd:COG3055   116 TALLLDGKIYVVGGWDDGGNVAWVE-VYDPATGTWTQLAP---LPTPRDHlaaaVLPDGKILVIGGRNG------SGFSN 185

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1039015507 241 IWERMDDDMASGWRGPAVVVAGDLYVLDQTFGAKLTMWCKD--TRMWIHIGKLSQLvmKQPCRLVSIGNSIFVIG 313
Cdd:COG3055   186 TWTTLAPLPTARAGHAAAVLGGKILVFGGESGFSDEVEAYDpaTNTWTALGELPTP--RHGHAAVLTDGKVYVIG 258
F-box_AtAFR-like cd22152
F-box domain found in Arabidopsis thaliana protein ATTENUATED FAR-RED RESPONSE (AtAFR) and ...
 21-65 2.38e-17

F-box domain found in Arabidopsis thaliana protein ATTENUATED FAR-RED RESPONSE (AtAFR) and similar proteins; AtAFR, also called SKP1-interacting partner 29 (AtSKIP29), or F-box protein AFR, is a component of SCF (SKP1/ASK-cullin-F-box protein) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins. It is part of the phyA-mediated signaling transduction pathway leading to the regulation of gene expression and hypocotyl elongation in response to red and far-red light exposure. This subfamily also includes many other Arabidopsis thaliana SKP1-interacting partner proteins. The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression.


Pssm-ID: 438923  Cd Length: 45  Bit Score: 74.91  E-value: 2.38e-17
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 1039015507  21 LISGVPDDISKSCLARVPREYHMAMKCVSRRWRDFVCSDEMCDYR 65
Cdd:cd22152     1 LIPGLPDDIALQCLARVPRSSHPSLSLVSKSWRSLLSSPELFRVR 45
F-box pfam00646
F-box domain; This domain is approximately 50 amino acids long, and is usually found in the ...
 22-60 6.66e-05

F-box domain; This domain is approximately 50 amino acids long, and is usually found in the N-terminal half of a variety of proteins. Two motifs that are commonly found associated with the F-box domain are the leucine rich repeats (LRRs; pfam00560 and pfam07723) and the WD repeat (pfam00400). The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression.


Pssm-ID: 425796  Cd Length: 43  Bit Score: 39.83  E-value: 6.66e-05
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 1039015507  22 ISGVPDDISKSCLARVPREYHMAMKCVSRRWRDFVCSDE 60
Cdd:pfam00646   1 LLDLPDDLLLEILSRLDPKDLLRLSLVSKRWRSLVDSLK 39
PRK14131 PRK14131
N-acetylneuraminate epimerase;
83-150 1.66e-04

N-acetylneuraminate epimerase;


Pssm-ID: 237617 [Multi-domain]  Cd Length: 376  Bit Score: 43.08  E-value: 1.66e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1039015507  83 SGGVFLHMLNPFSSRRSWKRINDYPYIPmREGMGFAVLGKRLFVLGGCGWLEDAT-----DEIYCYDAAMNTW 150
Cdd:PRK14131   47 SAGTSWYKLDLNAPSKGWTKIAAFPGGP-REQAVAAFIDGKLYVFGGIGKTNSEGspqvfDDVYKYDPKTNSW 118
Kelch smart00612
Kelch domain;
123-171 2.77e-04

Kelch domain;


Pssm-ID: 128874 [Multi-domain]  Cd Length: 47  Bit Score: 38.31  E-value: 2.77e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 1039015507  123 RLFVLGGCgWLEDATDEIYCYDAAMNTWFdVVPPLSTKRCYFACETLDG 171
Cdd:smart00612   1 KIYVVGGF-DGGQRLKSVEVYDPETNKWT-PLPSMPTPRSGHGVAVING 47
Kelch_6 pfam13964
Kelch motif;
161-207 8.22e-04

Kelch motif;


Pssm-ID: 404790 [Multi-domain]  Cd Length: 50  Bit Score: 36.93  E-value: 8.22e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 1039015507 161 RCYFACETLDGKIIAIGGLGLNPNAKRTWDIYDPLTRTCKSCSDVNI 207
Cdd:pfam13964   2 RTFHSVVSVGGYIYVFGGYTNASPALNKLEVYNPLTKSWEELPPLPT 48
FBOX smart00256
A Receptor for Ubiquitination Targets;
26-60 4.27e-03

A Receptor for Ubiquitination Targets;


Pssm-ID: 197608  Cd Length: 41  Bit Score: 34.72  E-value: 4.27e-03
                           10        20        30
                   ....*....|....*....|....*....|....*
gi 1039015507   26 PDDISKSCLARVPREYHMAMKCVSRRWRDFVCSDE 60
Cdd:smart00256   2 PDEILEEILSKLDPKDLLRLRKVSRKWRSLIDSHD 36
 
Name Accession Description Interval E-value
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
88-313 1.51e-19

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 87.13  E-value: 1.51e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039015507  88 LHMLNPfsSRRSWKRINDYPyIPMREGMGFAVLGKRLFVLGGCGWLED---ATDEIYCYDAAMNTWfDVVPPLSTKRCYF 164
Cdd:COG3055    40 FEVYDP--ATNTWSELAPLP-GPPRHHAAAVAQDGKLYVFGGFTGANPsstPLNDVYVYDPATNTW-TKLAPMPTPRGGA 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039015507 165 ACETLDGKIIAIGGLGLNPNAKRTWdIYDPLTRTCKSCSDvniVPEMEDS----FVMDGRIYIRGGVGGsstavySASSG 240
Cdd:COG3055   116 TALLLDGKIYVVGGWDDGGNVAWVE-VYDPATGTWTQLAP---LPTPRDHlaaaVLPDGKILVIGGRNG------SGFSN 185

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1039015507 241 IWERMDDDMASGWRGPAVVVAGDLYVLDQTFGAKLTMWCKD--TRMWIHIGKLSQLvmKQPCRLVSIGNSIFVIG 313
Cdd:COG3055   186 TWTTLAPLPTARAGHAAAVLGGKILVFGGESGFSDEVEAYDpaTNTWTALGELPTP--RHGHAAVLTDGKVYVIG 258
F-box_AtAFR-like cd22152
F-box domain found in Arabidopsis thaliana protein ATTENUATED FAR-RED RESPONSE (AtAFR) and ...
 21-65 2.38e-17

F-box domain found in Arabidopsis thaliana protein ATTENUATED FAR-RED RESPONSE (AtAFR) and similar proteins; AtAFR, also called SKP1-interacting partner 29 (AtSKIP29), or F-box protein AFR, is a component of SCF (SKP1/ASK-cullin-F-box protein) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins. It is part of the phyA-mediated signaling transduction pathway leading to the regulation of gene expression and hypocotyl elongation in response to red and far-red light exposure. This subfamily also includes many other Arabidopsis thaliana SKP1-interacting partner proteins. The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression.


Pssm-ID: 438923  Cd Length: 45  Bit Score: 74.91  E-value: 2.38e-17
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 1039015507  21 LISGVPDDISKSCLARVPREYHMAMKCVSRRWRDFVCSDEMCDYR 65
Cdd:cd22152     1 LIPGLPDDIALQCLARVPRSSHPSLSLVSKSWRSLLSSPELFRVR 45
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
99-266 6.71e-14

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 70.96  E-value: 6.71e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039015507  99 SWKRINDYPyIPMREGMGfAVLGKRLFVLGGCGWlEDATDEIYCYDAAMNTWFdVVPPLSTK-RCYFACETLDGKIIAIG 177
Cdd:COG3055     2 TWSSLPDLP-TPRSEAAA-ALLDGKVYVAGGLSG-GSASNSFEVYDPATNTWS-ELAPLPGPpRHHAAAVAQDGKLYVFG 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039015507 178 GLGLNPNAKRTWD---IYDPLTRTCKSCSDVNIVPEMEDSFVMDGRIYIRGGVGGS----STAVYSASSGIWERMdDDMA 250
Cdd:COG3055    78 GFTGANPSSTPLNdvyVYDPATNTWTKLAPMPTPRGGATALLLDGKIYVVGGWDDGgnvaWVEVYDPATGTWTQL-APLP 156

                         170
                  ....*....|....*...
gi 1039015507 251 SGWRGPAVVVAGD--LYV 266
Cdd:COG3055   157 TPRDHLAAAVLPDgkILV 174
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
149-267 4.70e-08

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 53.62  E-value: 4.70e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039015507 149 TWFDVvPPLSTKRCYFACETLDGKIIAIGGLGLNpNAKRTWDIYDPLTRTCKSCSDVNIVPEMED-SFVMDGRIYIRGGV 227
Cdd:COG3055     2 TWSSL-PDLPTPRSEAAAALLDGKVYVAGGLSGG-SASNSFEVYDPATNTWSELAPLPGPPRHHAaAVAQDGKLYVFGGF 79

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 1039015507 228 GG--------SSTAVYSASSGIWERMdDDMASGWRGP-AVVVAGDLYVL 267
Cdd:COG3055    80 TGanpsstplNDVYVYDPATNTWTKL-APMPTPRGGAtALLLDGKIYVV 127
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
99-193 8.00e-08

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 52.85  E-value: 8.00e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039015507  99 SWKRINDYPYipMREGMGFAVLGKRLFVLGGCGWledATDEIYCYDAAMNTWfDVVPPLSTKRCYFACETLDGKIIAIGG 178
Cdd:COG3055   186 TWTTLAPLPT--ARAGHAAAVLGGKILVFGGESG---FSDEVEAYDPATNTW-TALGELPTPRHGHAAVLTDGKVYVIGG 259

                          90
                  ....*....|....*...
gi 1039015507 179 L---GLNPNAKRTWDIYD 193
Cdd:COG3055   260 EtkpGVRTPLVTSAEVYD 277
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
99-238 2.67e-07

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 51.31  E-value: 2.67e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039015507  99 SWKRINDYPYIpmREGMGFAVLGKRLFVLGGCGWlEDATDEIYCYDAAMNTWfDVVPPLSTKRCYFACETL-DGKIIAIG 177
Cdd:COG3055   101 TWTKLAPMPTP--RGGATALLLDGKIYVVGGWDD-GGNVAWVEVYDPATGTW-TQLAPLPTPRDHLAAAVLpDGKILVIG 176

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039015507 178 GLGlNPNAKRTWD-----------------------------------IYDPLTRTCKSCSDVNIVPEMEDSFVMDGRIY 222
Cdd:COG3055   177 GRN-GSGFSNTWTtlaplptaraghaaavlggkilvfggesgfsdeveAYDPATNTWTALGELPTPRHGHAAVLTDGKVY 255

                         170
                  ....*....|....*....
gi 1039015507 223 IRGGV---GGSSTAVYSAS 238
Cdd:COG3055   256 VIGGEtkpGVRTPLVTSAE 274
F-box pfam00646
F-box domain; This domain is approximately 50 amino acids long, and is usually found in the ...
 22-60 6.66e-05

F-box domain; This domain is approximately 50 amino acids long, and is usually found in the N-terminal half of a variety of proteins. Two motifs that are commonly found associated with the F-box domain are the leucine rich repeats (LRRs; pfam00560 and pfam07723) and the WD repeat (pfam00400). The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression.


Pssm-ID: 425796  Cd Length: 43  Bit Score: 39.83  E-value: 6.66e-05
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 1039015507  22 ISGVPDDISKSCLARVPREYHMAMKCVSRRWRDFVCSDE 60
Cdd:pfam00646   1 LLDLPDDLLLEILSRLDPKDLLRLSLVSKRWRSLVDSLK 39
PRK14131 PRK14131
N-acetylneuraminate epimerase;
83-150 1.66e-04

N-acetylneuraminate epimerase;


Pssm-ID: 237617 [Multi-domain]  Cd Length: 376  Bit Score: 43.08  E-value: 1.66e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1039015507  83 SGGVFLHMLNPFSSRRSWKRINDYPYIPmREGMGFAVLGKRLFVLGGCGWLEDAT-----DEIYCYDAAMNTW 150
Cdd:PRK14131   47 SAGTSWYKLDLNAPSKGWTKIAAFPGGP-REQAVAAFIDGKLYVFGGIGKTNSEGspqvfDDVYKYDPKTNSW 118
PHA03098 PHA03098
kelch-like protein; Provisional
 100-322 2.22e-04

kelch-like protein; Provisional


Pssm-ID: 222983 [Multi-domain]  Cd Length: 534  Bit Score: 42.83  E-value: 2.22e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039015507 100 WKRINDYPYIPMREGMGFAVLGKRLFVLGGCGWLEDATDEIYCYDAAMNTWFDVvPPLSTKRCYFACETLDGKIIAIGGL 179
Cdd:PHA03098  273 LSEINTIIDIHYVYCFGSVVLNNVIYFIGGMNKNNLSVNSVVSYDTKTKSWNKV-PELIYPRKNPGVTVFNNRIYVIGGI 351

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039015507 180 GLNP--NAKRTWDIYDPLTRTCKSCsdvnIVPEMEDSFVM-DGRIYIRGGVGGSSTA-----VYSASSGIWERMDDDMAS 251
Cdd:PHA03098  352 YNSIslNTVESWKPGESKWREEPPL----IFPRYNPCVVNvNNLIYVIGGISKNDELlktveCFSLNTNKWSKGSPLPIS 427

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039015507 252 GWRGPAVVVAGDLYVLDQTFGAKL-----------TMWCKdtrmWIHIGKLSQLVMKQpcRLVSIGNSIFVIGKDCSTVV 320
Cdd:PHA03098  428 HYGGCAIYHDGKIYVIGGISYIDNikvynivesynPVTNK----WTELSSLNFPRINA--SLCIFNNKIYVVGGDKYEYY 501


                  ..
gi 1039015507 321 ID 322
Cdd:PHA03098  502 IN 503
Kelch smart00612
Kelch domain;
123-171 2.77e-04

Kelch domain;


Pssm-ID: 128874 [Multi-domain]  Cd Length: 47  Bit Score: 38.31  E-value: 2.77e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 1039015507  123 RLFVLGGCgWLEDATDEIYCYDAAMNTWFdVVPPLSTKRCYFACETLDG 171
Cdd:smart00612   1 KIYVVGGF-DGGQRLKSVEVYDPETNKWT-PLPSMPTPRSGHGVAVING 47
Kelch_6 pfam13964
Kelch motif;
161-207 8.22e-04

Kelch motif;


Pssm-ID: 404790 [Multi-domain]  Cd Length: 50  Bit Score: 36.93  E-value: 8.22e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 1039015507 161 RCYFACETLDGKIIAIGGLGLNPNAKRTWDIYDPLTRTCKSCSDVNI 207
Cdd:pfam13964   2 RTFHSVVSVGGYIYVFGGYTNASPALNKLEVYNPLTKSWEELPPLPT 48
F-box_AtFBW1-like cd22157
F-box domain found in Arabidopsis thaliana F-box/WD-40 repeat-containing protein 1 (AtFBW1) ...
 23-53 1.04e-03

F-box domain found in Arabidopsis thaliana F-box/WD-40 repeat-containing protein 1 (AtFBW1) and similar proteins; AtFBW1, also called WD-40-associated F-box protein 1, is an F-box protein that contains four WD-40 repeats, which are separated from each other by a spacer region. Like other F-box proteins, AtFBW1 may be a component of SCF (Skp1 Cdc53 F-box protein) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins. This subfamily also contains many F-box only proteins that do not have any WD repeat. The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression.


Pssm-ID: 438928  Cd Length: 39  Bit Score: 36.29  E-value: 1.04e-03
                          10        20        30
                  ....*....|....*....|....*....|.
gi 1039015507  23 SGVPDDISKSCLARVPREYHMAMKCVSRRWR 53
Cdd:cd22157     1 SSLPDDLVEEILSRLPAKSLLRFRCVCKQWN 31
FBOX smart00256
A Receptor for Ubiquitination Targets;
26-60 4.27e-03

A Receptor for Ubiquitination Targets;


Pssm-ID: 197608  Cd Length: 41  Bit Score: 34.72  E-value: 4.27e-03
                           10        20        30
                   ....*....|....*....|....*....|....*
gi 1039015507   26 PDDISKSCLARVPREYHMAMKCVSRRWRDFVCSDE 60
Cdd:smart00256   2 PDEILEEILSKLDPKDLLRLRKVSRKWRSLIDSHD 36
Kelch_4 pfam13418
Galactose oxidase, central domain;
114-150 8.78e-03

Galactose oxidase, central domain;


Pssm-ID: 433191 [Multi-domain]  Cd Length: 49  Bit Score: 34.12  E-value: 8.78e-03
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 1039015507 114 GMGFAVLGKRLFVLGGCGWLEDATDEIYCYDAAMNTW 150
Cdd:pfam13418   5 HTSTSIPDDTIYLFGGEGEDGTLLSDLWVFDLSTNEW 41
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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