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Conserved domains on  [gi|1042059102|gb|ANP80983|]
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transcriptional regulator [Bacillus sp. B25(2016b)]

Protein Classification

MarR family winged helix-turn-helix transcriptional regulator( domain architecture ID 11448790)

MarR family winged helix-turn-helix (wHTH) transcriptional regulator similar to Bacillus thuringiensis DNA-binding transcriptional repressor TubR, a DNA-binding protein that is part of the type III plasmid partition system used to ensure correct segregation of the pBtoxis plasmid

Gene Ontology:  GO:0006355|GO:0003700
PubMed:  10498949|28670937
SCOP:  4000246

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MarR COG1846
DNA-binding transcriptional regulator, MarR family [Transcription];
2-138 4.32e-28

DNA-binding transcriptional regulator, MarR family [Transcription];


:

Pssm-ID: 441451 [Multi-domain]  Cd Length: 142  Bit Score: 100.81  E-value: 4.32e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1042059102   2 RDNTIGSLIWLRLIRFTNQSNQMSNEFLKRFDLTTAQFDVLLQIRTYQPLTQMELAEKVTVTQGGISRMLTRLEKEGYIV 81
Cdd:COG1846     4 EPDPAEERLGLLLRRLARALRRALDRALAELGLTPAQFRVLAALAEAGGLTQSELAERLGLTKSTVSRLLDRLEEKGLVE 83

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1042059102  82 RK---QDWKTKTISLTEQGEAALERALPEQLAFQSSFFDDvLNEEEQKILYELMTKVHKH 138
Cdd:COG1846    84 REpdpEDRRAVLVRLTEKGRALLEEARPALEALLAELLAG-LSEEELEALLRLLRRLAEN 142
 
Name Accession Description Interval E-value
MarR COG1846
DNA-binding transcriptional regulator, MarR family [Transcription];
2-138 4.32e-28

DNA-binding transcriptional regulator, MarR family [Transcription];


Pssm-ID: 441451 [Multi-domain]  Cd Length: 142  Bit Score: 100.81  E-value: 4.32e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1042059102   2 RDNTIGSLIWLRLIRFTNQSNQMSNEFLKRFDLTTAQFDVLLQIRTYQPLTQMELAEKVTVTQGGISRMLTRLEKEGYIV 81
Cdd:COG1846     4 EPDPAEERLGLLLRRLARALRRALDRALAELGLTPAQFRVLAALAEAGGLTQSELAERLGLTKSTVSRLLDRLEEKGLVE 83

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1042059102  82 RK---QDWKTKTISLTEQGEAALERALPEQLAFQSSFFDDvLNEEEQKILYELMTKVHKH 138
Cdd:COG1846    84 REpdpEDRRAVLVRLTEKGRALLEEARPALEALLAELLAG-LSEEELEALLRLLRRLAEN 142
HTH_MARR smart00347
helix_turn_helix multiple antibiotic resistance protein;
27-125 1.61e-21

helix_turn_helix multiple antibiotic resistance protein;


Pssm-ID: 197670 [Multi-domain]  Cd Length: 101  Bit Score: 82.64  E-value: 1.61e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1042059102   27 EFLKRFDLTTAQFDVLLQIRTYQPLTQMELAEKVTVTQGGISRMLTRLEKEGYIVRKQ---DWKTKTISLTEQGEAALER 103
Cdd:smart00347   1 EELKPLGLTPTQFLVLRILYEEGPLSVSELAKRLGVSPSTVTRVLDRLEKKGLVRREPspeDRRSVLVSLTEEGRELIEQ 80

                           90       100
                   ....*....|....*....|..
gi 1042059102  104 ALPEQLAFQSSFFDDvLNEEEQ 125
Cdd:smart00347  81 LLEARSETLAELLAG-LTAEEQ 101
PRK11512 PRK11512
multiple antibiotic resistance transcriptional regulator MarR;
13-103 1.32e-11

multiple antibiotic resistance transcriptional regulator MarR;


Pssm-ID: 183170  Cd Length: 144  Bit Score: 58.37  E-value: 1.32e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1042059102  13 RLIRFTNQS-NQMSNEFLKRFDLTTAQFDVLLQIRTYQPLTQMELAEKVTVTQGGISRMLTRLEKEGYIVR---KQDWKT 88
Cdd:PRK11512   16 RLIHMVNQKkDRLLNEYLSPLDITAAQFKVLCSIRCAACITPVELKKVLSVDLGALTRMLDRLVCKGWVERlpnPNDKRG 95

                          90
                  ....*....|....*
gi 1042059102  89 KTISLTEQGEAALER 103
Cdd:PRK11512   96 VLVKLTTSGAAICEQ 110
MarR_2 pfam12802
MarR family; The Mar proteins are involved in the multiple antibiotic resistance, a ...
 32-85 3.13e-11

MarR family; The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system. The expression of the mar operon is controlled by a repressor, MarR. A large number of compounds induce transcription of the mar operon. This is thought to be due to the compound binding to MarR, and the resulting complex stops MarR binding to the DNA. With the MarR repression lost, transcription of the operon proceeds. The structure of MarR is known and shows MarR as a dimer with each subunit containing a winged-helix DNA binding motif.


Pssm-ID: 432797 [Multi-domain]  Cd Length: 60  Bit Score: 55.29  E-value: 3.13e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1042059102  32 FDLTTAQFDVLLQIRTYQPLTQMELAEKVTVTQGGISRMLTRLEKEGYIVRKQD 85
Cdd:pfam12802   1 LGLTPAQFRVLLALARNPGLTVAELARRLGISKQTVSRLVKRLEAKGLVEREPS 54
HTH_ARSR cd00090
Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric ...
 50-100 5.59e-05

Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.


Pssm-ID: 238042 [Multi-domain]  Cd Length: 78  Bit Score: 39.20  E-value: 5.59e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1042059102  50 PLTQMELAEKVTVTQGGISRMLTRLEKEGYIVRKQDWKTKTISLTEQGEAA 100
Cdd:cd00090    20 PLTVSELAERLGLSQSTVSRHLKKLEEAGLVESRREGRRVYYSLTDAERLL 70
 
Name Accession Description Interval E-value
MarR COG1846
DNA-binding transcriptional regulator, MarR family [Transcription];
2-138 4.32e-28

DNA-binding transcriptional regulator, MarR family [Transcription];


Pssm-ID: 441451 [Multi-domain]  Cd Length: 142  Bit Score: 100.81  E-value: 4.32e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1042059102   2 RDNTIGSLIWLRLIRFTNQSNQMSNEFLKRFDLTTAQFDVLLQIRTYQPLTQMELAEKVTVTQGGISRMLTRLEKEGYIV 81
Cdd:COG1846     4 EPDPAEERLGLLLRRLARALRRALDRALAELGLTPAQFRVLAALAEAGGLTQSELAERLGLTKSTVSRLLDRLEEKGLVE 83

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1042059102  82 RK---QDWKTKTISLTEQGEAALERALPEQLAFQSSFFDDvLNEEEQKILYELMTKVHKH 138
Cdd:COG1846    84 REpdpEDRRAVLVRLTEKGRALLEEARPALEALLAELLAG-LSEEELEALLRLLRRLAEN 142
HTH_MARR smart00347
helix_turn_helix multiple antibiotic resistance protein;
27-125 1.61e-21

helix_turn_helix multiple antibiotic resistance protein;


Pssm-ID: 197670 [Multi-domain]  Cd Length: 101  Bit Score: 82.64  E-value: 1.61e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1042059102   27 EFLKRFDLTTAQFDVLLQIRTYQPLTQMELAEKVTVTQGGISRMLTRLEKEGYIVRKQ---DWKTKTISLTEQGEAALER 103
Cdd:smart00347   1 EELKPLGLTPTQFLVLRILYEEGPLSVSELAKRLGVSPSTVTRVLDRLEKKGLVRREPspeDRRSVLVSLTEEGRELIEQ 80

                           90       100
                   ....*....|....*....|..
gi 1042059102  104 ALPEQLAFQSSFFDDvLNEEEQ 125
Cdd:smart00347  81 LLEARSETLAELLAG-LTAEEQ 101
PRK11512 PRK11512
multiple antibiotic resistance transcriptional regulator MarR;
13-103 1.32e-11

multiple antibiotic resistance transcriptional regulator MarR;


Pssm-ID: 183170  Cd Length: 144  Bit Score: 58.37  E-value: 1.32e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1042059102  13 RLIRFTNQS-NQMSNEFLKRFDLTTAQFDVLLQIRTYQPLTQMELAEKVTVTQGGISRMLTRLEKEGYIVR---KQDWKT 88
Cdd:PRK11512   16 RLIHMVNQKkDRLLNEYLSPLDITAAQFKVLCSIRCAACITPVELKKVLSVDLGALTRMLDRLVCKGWVERlpnPNDKRG 95

                          90
                  ....*....|....*
gi 1042059102  89 KTISLTEQGEAALER 103
Cdd:PRK11512   96 VLVKLTTSGAAICEQ 110
MarR_2 pfam12802
MarR family; The Mar proteins are involved in the multiple antibiotic resistance, a ...
 32-85 3.13e-11

MarR family; The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system. The expression of the mar operon is controlled by a repressor, MarR. A large number of compounds induce transcription of the mar operon. This is thought to be due to the compound binding to MarR, and the resulting complex stops MarR binding to the DNA. With the MarR repression lost, transcription of the operon proceeds. The structure of MarR is known and shows MarR as a dimer with each subunit containing a winged-helix DNA binding motif.


Pssm-ID: 432797 [Multi-domain]  Cd Length: 60  Bit Score: 55.29  E-value: 3.13e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1042059102  32 FDLTTAQFDVLLQIRTYQPLTQMELAEKVTVTQGGISRMLTRLEKEGYIVRKQD 85
Cdd:pfam12802   1 LGLTPAQFRVLLALARNPGLTVAELARRLGISKQTVSRLVKRLEAKGLVEREPS 54
MarR pfam01047
MarR family; The Mar proteins are involved in the multiple antibiotic resistance, a ...
 34-85 2.79e-10

MarR family; The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system. The expression of the mar operon is controlled by a repressor, MarR. A large number of compounds induce transcription of the mar operon. This is thought to be due to the compound binding to MarR, and the resulting complex stops MarR binding to the DNA. With the MarR repression lost, transcription of the operon proceeds. The structure of MarR is known and shows MarR as a dimer with each subunit containing a winged-helix DNA binding motif.


Pssm-ID: 426012 [Multi-domain]  Cd Length: 59  Bit Score: 52.55  E-value: 2.79e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1042059102  34 LTTAQFDVLLQIRTYQPLTQMELAEKVTVTQGGISRMLTRLEKEGYIVRKQD 85
Cdd:pfam01047   1 LTLTQFHILRILYEHGPLTVSELAEKLGVSKSTVTRVLDRLEKKGLIERSRS 52
LexA COG1974
SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase) [Transcription, ...
 33-102 4.46e-07

SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase) [Transcription, Signal transduction mechanisms];


Pssm-ID: 441577 [Multi-domain]  Cd Length: 199  Bit Score: 47.22  E-value: 4.46e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1042059102  33 DLTTAQFDVLLQIRTYQ-----PLTQMELAEKVTVTQGGISRMLTRLEKEGYIvRKQDWKTKTISLTEQGEAALE 102
Cdd:COG1974     3 KLTKRQREILDFIKEYIrergyPPSQREIAEALGLSSSAVHRHLKALEKKGYL-RRDPGKSRAIELLPASPEVVG 76
Rfk COG1339
Archaeal CTP-dependent riboflavin kinase [Coenzyme transport and metabolism]; Archaeal ...
 51-103 1.43e-06

Archaeal CTP-dependent riboflavin kinase [Coenzyme transport and metabolism]; Archaeal CTP-dependent riboflavin kinase is part of the Pathway/BioSystem: Riboflavin/FAD biosynthesis


Pssm-ID: 440950 [Multi-domain]  Cd Length: 219  Bit Score: 45.61  E-value: 1.43e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1042059102  51 LTQMELAEKVTVTQGGISRMLTRLEKEGYIVRKQDWKTKTISLTEQGEAALER 103
Cdd:COG1339    23 ISSSELAKRLGISQQTASRRLQELEDAGLIERDLVGDGQWVKITEKGEELLRR 75
COG2512 COG2512
Predicted transcriptional regulator, contains CW (cell wall-binding) repeats and an HTH domain ...
 51-100 1.71e-05

Predicted transcriptional regulator, contains CW (cell wall-binding) repeats and an HTH domain [General function prediction only];


Pssm-ID: 442002 [Multi-domain]  Cd Length: 80  Bit Score: 40.67  E-value: 1.71e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1042059102  51 LTQMELAEKVTVTQGGISRMLTRLEKEGYIVRKQDWKTKTISLTEQGEAA 100
Cdd:COG2512    31 MTQSEIVKETGWSKSKVSRLLSRLEERGLIEKERVGRENVVELPEDEPEA 80
MntR COG1321
Mn-dependent transcriptional regulator MntR, DtxR family [Transcription];
31-105 2.61e-05

Mn-dependent transcriptional regulator MntR, DtxR family [Transcription];


Pssm-ID: 440932 [Multi-domain]  Cd Length: 135  Bit Score: 41.34  E-value: 2.61e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1042059102  31 RFDLTTAQFDVLLQI----RTYQPLTQMELAEKVTVTQGGISRMLTRLEKEGYIVRKQDwktKTISLTEQGEAALERAL 105
Cdd:COG1321     1 MMMLSESEEDYLKAIyelsEEGGPVRTSDIAERLGVSPPSVTEMLKKLEEKGLVEYEPY---GGITLTEEGRELALRIV 76
HTH_ARSR cd00090
Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric ...
 50-100 5.59e-05

Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.


Pssm-ID: 238042 [Multi-domain]  Cd Length: 78  Bit Score: 39.20  E-value: 5.59e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1042059102  50 PLTQMELAEKVTVTQGGISRMLTRLEKEGYIVRKQDWKTKTISLTEQGEAA 100
Cdd:cd00090    20 PLTVSELAERLGLSQSTVSRHLKKLEEAGLVESRREGRRVYYSLTDAERLL 70
HTH_34 pfam13601
Winged helix DNA-binding domain;
55-103 1.90e-04

Winged helix DNA-binding domain;


Pssm-ID: 463932 [Multi-domain]  Cd Length: 80  Bit Score: 38.00  E-value: 1.90e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1042059102  55 ELAEKVTVTQGGISRMLTRLEKEGYIVRKQDWKTK----TISLTEQGEAALER 103
Cdd:pfam13601  19 ELKEALEATDGNLSVHLRKLEKAGYIECDKSFVGRkprtLYRITPEGREAFED 71
PRK11050 PRK11050
manganese-binding transcriptional regulator MntR;
53-104 2.53e-04

manganese-binding transcriptional regulator MntR;


Pssm-ID: 182927 [Multi-domain]  Cd Length: 152  Bit Score: 38.84  E-value: 2.53e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1042059102  53 QMELAEKVTVTQGGISRMLTRLEKEGYIVRKqdwKTKTISLTEQGEAALERA 104
Cdd:PRK11050   54 QVDIAARLGVSQPTVAKMLKRLARDGLVEMR---PYRGVFLTPEGEKLAQES 102
HTH_DTXR smart00529
Helix-turn-helix diphteria tox regulatory element; iron dependent repressor
 54-105 4.52e-04

Helix-turn-helix diphteria tox regulatory element; iron dependent repressor


Pssm-ID: 197774 [Multi-domain]  Cd Length: 95  Bit Score: 37.20  E-value: 4.52e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1042059102   54 MELAEKVTVTQGGISRMLTRLEKEGYIVRKQDwktKTISLTEQGEAALERAL 105
Cdd:smart00529   2 SEIAERLNVSPPTVTEMLKKLEKMGLVEYEPY---RGITLTEKGRRLARRLL 50
COG2345 COG2345
Predicted transcriptional regulator, ArsR family [Transcription];
24-104 5.37e-04

Predicted transcriptional regulator, ArsR family [Transcription];


Pssm-ID: 441914 [Multi-domain]  Cd Length: 217  Bit Score: 38.37  E-value: 5.37e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1042059102  24 MSNEFLKRFDLTTAQFDVLLQIRTYQPLTQMELAEKVTVTQGGISRMLTRLEKEGYIVRKQDWK-----TKTISLTEQGE 98
Cdd:COG2345     1 MTDTPALAALADPTRRRILELLKRAGPVTAAELAEALGLTPNAVRRHLDALEEEGLVERETERRgrgrpAKLYRLTEAGR 80


                  ....*.
gi 1042059102  99 AALERA 104
Cdd:COG2345    81 ARFPRA 86
COG3398 COG3398
Predicted transcriptional regulator, contains two HTH domains [Transcription];
40-95 1.12e-03

Predicted transcriptional regulator, contains two HTH domains [Transcription];


Pssm-ID: 442625 [Multi-domain]  Cd Length: 159  Bit Score: 37.17  E-value: 1.12e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1042059102  40 DVLLQIRTYQPLTQMELAEKVTVTQGGISRMLTRLEKEGYIVRKQDWKTKTISLTE 95
Cdd:COG3398   101 RILLYLLENPGATNKELAEELGISRSTVSWHLKRLEEDGLVERERDGRNVRYYLNP 156
PRK14165 PRK14165
winged helix-turn-helix domain-containing protein/riboflavin kinase; Provisional
 51-103 1.45e-03

winged helix-turn-helix domain-containing protein/riboflavin kinase; Provisional


Pssm-ID: 184548 [Multi-domain]  Cd Length: 217  Bit Score: 37.35  E-value: 1.45e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1042059102  51 LTQMELAEKVTVTQGGISRMLTRLEKEGYIVRKQDWKTKTISLTEQGEAALER 103
Cdd:PRK14165   22 ISSSEFANHTGTSSKTAARILKQLEDEGYITRTIVPRGQLITITEKGLDVLYN 74
PadR COG1695
DNA-binding transcriptional regulator, PadR family [Transcription];
30-114 1.72e-03

DNA-binding transcriptional regulator, PadR family [Transcription];


Pssm-ID: 441301  Cd Length: 102  Bit Score: 35.68  E-value: 1.72e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1042059102  30 KRFDLTTAQFDVLLQIRTyQPLTQMELAEKV--------TVTQGGISRMLTRLEKEGYIVRKQDWKT-----KTISLTEQ 96
Cdd:COG1695     3 RQLRKGTLELLILALLAE-GPMYGYEIIKELeersggfwKVSEGTLYPALKRLEKEGLVESEWEESEggprrKYYRLTEA 81

                          90
                  ....*....|....*...
gi 1042059102  97 GEAALERALPEQLAFQSS 114
Cdd:COG1695    82 GREELAEWLEEWEKLAEA 99
HTH_CRP cd00092
helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic ...
 50-85 2.04e-03

helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family.


Pssm-ID: 238044 [Multi-domain]  Cd Length: 67  Bit Score: 34.95  E-value: 2.04e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 1042059102  50 PLTQMELAEKVTVTQGGISRMLTRLEKEGYIVRKQD 85
Cdd:cd00092    25 PLTRQEIADYLGLTRETVSRTLKELEEEGLISRRGR 60
LysR COG0583
DNA-binding transcriptional regulator, LysR family [Transcription];
57-104 2.14e-03

DNA-binding transcriptional regulator, LysR family [Transcription];


Pssm-ID: 440348 [Multi-domain]  Cd Length: 256  Bit Score: 36.77  E-value: 2.14e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1042059102  57 AEKVTVTQGGISRMLTRLEKE-GY--IVRkqdwKTKTISLTEQGEAALERA 104
Cdd:COG0583    22 AERLGVSQPAVSRQIRRLEEElGVplFER----TGRGLRLTEAGERLLERA 68
HTH_24 pfam13412
Winged helix-turn-helix DNA-binding;
38-80 2.24e-03

Winged helix-turn-helix DNA-binding;


Pssm-ID: 404317 [Multi-domain]  Cd Length: 45  Bit Score: 33.95  E-value: 2.24e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 1042059102  38 QFDVLLQIRTYQPLTQMELAEKVTVTQGGISRMLTRLEKEGYI 80
Cdd:pfam13412   3 DRKILNLLQENPRISQRELAERLGLSPSTVNRRLKRLEEEGVI 45
DeoR COG2390
DNA-binding transcriptional regulator LsrR, DeoR family [Transcription];
49-105 3.56e-03

DNA-binding transcriptional regulator LsrR, DeoR family [Transcription];


Pssm-ID: 441955 [Multi-domain]  Cd Length: 301  Bit Score: 36.26  E-value: 3.56e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1042059102  49 QPLTQMELAEKVTVTQGGISRMLTRLEKEGyIVRkqdwktktISLTE--QGEAALERAL 105
Cdd:COG2390     9 EGLTQREIAERLGISRRTVSRLLAEAREEG-LVR--------ISITDplAGLLELEREL 58
COG3888 COG3888
Predicted transcriptional regulator [Transcription];
42-105 3.65e-03

Predicted transcriptional regulator [Transcription];


Pssm-ID: 443096 [Multi-domain]  Cd Length: 328  Bit Score: 36.15  E-value: 3.65e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1042059102  42 LLQIRTYQPLTQMELAEKVTVTQGGISRMLTRLEKEGYIVRKQD-WKTKTISLTEQGEAALERAL 105
Cdd:COG3888    11 ILKNYGGEGIPQSELVRLLGASKSRVSEILSELEKEGLIARKKViGKSKRVWLREYYPEPDDKVL 75
pheS PRK04172
phenylalanine--tRNA ligase subunit alpha;
34-107 4.97e-03

phenylalanine--tRNA ligase subunit alpha;


Pssm-ID: 235239 [Multi-domain]  Cd Length: 489  Bit Score: 35.96  E-value: 4.97e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1042059102  34 LTTAQFDVLLQIRTYQPLTQMELAEKVTVTQGGISRMLTRLEKEGYI-VRKQdwKTKTISLTEQGEAALERALPE 107
Cdd:PRK04172    4 LHPNEKKVLKALKELKEATLEELAEKLGLPPEAVMRAAEWLEEKGLVkVEER--VEEVYVLTEEGKKYAEEGLPE 76
COG4742 COG4742
Predicted transcriptional regulator, contains HTH domain [Transcription];
40-106 6.20e-03

Predicted transcriptional regulator, contains HTH domain [Transcription];


Pssm-ID: 443776 [Multi-domain]  Cd Length: 267  Bit Score: 35.64  E-value: 6.20e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1042059102  40 DVLLQIRTyQPLTQMELAEKVTVTQGGISRMLTRLEKEGYIVRKQDwktkTISLTEQGEAALERALP 106
Cdd:COG4742    20 NILLLLAE-GPKTRSELAESLDVSRSTILRQLKELEERGLIERDDG----EYELTTLGRLVVEEMEP 81
HTH_CRP smart00419
helix_turn_helix, cAMP Regulatory protein;
50-83 6.44e-03

helix_turn_helix, cAMP Regulatory protein;


Pssm-ID: 128696 [Multi-domain]  Cd Length: 48  Bit Score: 32.80  E-value: 6.44e-03
                           10        20        30
                   ....*....|....*....|....*....|....
gi 1042059102   50 PLTQMELAEKVTVTQGGISRMLTRLEKEGYIVRK 83
Cdd:smart00419   8 PLTRQEIAELLGLTRETVSRTLKRLEKEGLISRE 41
HTH_Crp_2 pfam13545
Crp-like helix-turn-helix domain; This family represents a crp-like helix-turn-helix domain ...
 50-84 7.92e-03

Crp-like helix-turn-helix domain; This family represents a crp-like helix-turn-helix domain that is likely to bind DNA.


Pssm-ID: 463917 [Multi-domain]  Cd Length: 68  Bit Score: 33.20  E-value: 7.92e-03
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 1042059102  50 PLTQMELAEKVTVTQGGISRMLTRLEKEGYIVRKQ 84
Cdd:pfam13545  22 PLTQEDLADLLGTTRETVSRVLSELRREGLIERGR 56
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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