|
Name |
Accession |
Description |
Interval |
E-value |
| CusA |
COG3696 |
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism]; |
1-996 |
0e+00 |
|
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
Pssm-ID: 442911 [Multi-domain] Cd Length: 1031 Bit Score: 1258.40 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 1 MRKLIAFALSQRLLAAVLAIALVGLGANAFLKLPVDAFPDISPTQVKIILKAPGMTPEEVESQVITPLEMELLGIPKQAM 80
Cdd:COG3696 2 LNRIIRFSLRNRLLVLLLTLLLAAAGIYSLRRLPIDAFPDITNVQVQVITEAPGLSPEEVEQQVTYPIETALNGLPGVKE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 81 LRSTAKYAIADLTIDFAPGTDVYWARQQTAERLSNALGALPAGVSGGLSPISTPLSDVFMFTIEGEG--LTLEQKRTLLD 158
Cdd:COG3696 82 VRSISRFGLSVVTVIFEDGTDIYWARQLVLERLQQVREQLPAGVTPELGPISTGLGEIYQYTLESDPgkYSLMELRTLQD 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 159 WTVRPALRGLPGVADVNVLGGRAKTFEVSPDPAALAASGLTAQAIIDAIPASNRNDGSGRLSEGEEALVVRVAGAITSLD 238
Cdd:COG3696 162 WVIRPQLRSVPGVAEVNSFGGFVKQYQVLVDPAKLRAYGLTLDDVIEALERNNANVGGGYIERGGQEYLVRGIGLIRSLE 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 239 DLRDTAIALPSGGAARLGDLAEVSEGALTRYGAVTENGREEAVQAIVIALRGADAKAVVRSVEARLKELQPSLPKGVTVS 318
Cdd:COG3696 242 DIENIVVKTRNGTPVLLRDVAEVRIGPAPRRGAATLNGEGEVVGGIVLMLKGENALEVIEAVKAKLAELKPSLPEGVKIV 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 319 PFYNRSDLIQRATGTVNKALVEATVLVVILLLLFLGDLRAATVVAVTLPLAALTTFLLMRTFGLSANLMSLGGLAIAIGM 398
Cdd:COG3696 322 PFYDRSDLIDRAIHTVTKNLLEGALLVILVLFLFLGNLRAALIVALAIPLSLLFAFIVMRLFGISANLMSLGGLAIDFGI 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 399 LVDAAVVVVENTVERLDNPNIAGSR--RLHAIYEAVAEVAAPVTSGVLIICLVFLPLLSLQGLEGKLFAPVALTIVFALG 476
Cdd:COG3696 402 IVDGAVVMVENILRRLEENRAAGTPreRLEVVLEAAREVRRPIFFATLIIILVFLPIFTLEGVEGKLFRPMALTVIFALL 481
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 477 SSLLLSFTVIPVLASLLLK-AHPHRESWIMRRIGPFYERQLARSLSRPKPVFAAAGGGMVLAAIAYVLIGKSFMPTMDEG 555
Cdd:COG3696 482 GALLLSLTLVPVLASLLLRgKVPEKENPLVRWLKRLYRPLLRWALRHPKLVLAVALVLLVLALALFPRLGSEFLPELDEG 561
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 556 AILMQLAKLPSINLDASAKQDMAVQRaILAQVPEVKRIVARVGSDELGLDPMGLNETDSFLVLADRKDWRR-KDKAWLTE 634
Cdd:COG3696 562 DLLVMATLPPGISLEESVELGQQVER-ILKSFPEVESVVSRTGRAEDATDPMGVNMSETFVILKPRSEWRSgRTKEELIA 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 635 EIRKVAAQFPGVEATFTQPIEMRVSEMLTGSRGDLAVKVFGPDLQTLGDLAGRIEETLKKTRGASDVYTVAGDSVTYLQL 714
Cdd:COG3696 641 EMREALEQIPGVNFNFSQPIQMRVDELLSGVRADVAVKIFGDDLDVLRRLAEQIEAVLKTVPGAADVQVERVTGLPQLDI 720
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 715 DVDRGAAVRAGLSAQALQQELRAQLEGAPAGVVFEQGKRTPILVRGPQDLREDPVLFEQAQIATPDGGVVRAGDVARIQR 794
Cdd:COG3696 721 RIDRDAAARYGLNVADVQDVVETAIGGKAVGQVYEGERRFDIVVRLPEELRDDPEAIRNLPIPTPSGAQVPLSQVADIEV 800
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 795 REGPVKIDRENASRFAVIQAYVQGRDLVGFVKEAQANVARDVPLPPGYRIAWGGQFENQKRAAARLGVVVPMALCLIFLV 874
Cdd:COG3696 801 VEGPNQISRENGRRRIVVQANVRGRDLGSFVAEAQAKVAEQVKLPPGYYIEWGGQFENLQRATARLAIVVPLALLLIFLL 880
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 875 LFISLKSTRQSLLILANIPFAMIGGLVALWISGEYLSVPASVGLIALLGIAVLNGLVLVSHFNELVQRGCDVATAVTEGA 954
Cdd:COG3696 881 LYLAFGSVRDALLILLNVPFALIGGVLALWLRGMPLSVSAGVGFIALFGVAVLNGVVLVSYINQLRAEGLDLREAIIEGA 960
|
970 980 990 1000
....*....|....*....|....*....|....*....|..
gi 1243374125 955 RRRLRPVLMTASITALGLVPLLTATGPGSEIQRPLAIVVVGG 996
Cdd:COG3696 961 LERLRPVLMTALVAALGLLPMALSTGPGSEVQRPLATVVIGG 1002
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
4-996 |
0e+00 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 813.84 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 4 LIAFALSQRLLAAVLAIALVGLGANAFLKLPVDAFPDISPTQVKIILKAPGMTPEEVESQVITPLEMELLGIPKQAMLRS 83
Cdd:pfam00873 1 MSKFFIRRPIFTLVLAIAILLAGILSFFSLPVDAFPEIAPPTVQVSTSYPGASPEEVEDTVTQPIEQAMNGLDGLKYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 84 TAKYAIADLTIDFAPGTDVYWARQQTAERLSNALGALPAGVS-GGLSPISTPLSDVFMFTIEGEG--LTLEQKRTLLDWT 160
Cdd:pfam00873 81 QSSYGLSSITLTFELGTDIDIARQDVQNRLQLATPLLPEGVQrPGISVIKTSLGPIMVLAVTSPDgsYTQTDLRDYADTN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 161 VRPALRGLPGVADVNVLGGRAKTFEVSPDPAALAASGLTAQAIIDAIPASNRNDGSGRLSEGEEALVVRVAGAITSLDDL 240
Cdd:pfam00873 161 IKPQLSRVPGVGDVQLFGGSEYAMRIWLDPQKLARYGLTLTDVVSALKEQNVNIGAGQLEGQGLQALIRAQGQLQSAEDF 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 241 RDTAIALPSGGAARLGDLAEVSEGALTRYGAVTENGrEEAVQAIVIALRGADAKAVVRSVEARLKELQPSLPKGVTVSPF 320
Cdd:pfam00873 241 EKIIVKNQDGSPVRLRDVATVELGSELYRGFATFNG-KPAVGLGVQKLPGANAIETADAVRAKLAELKPTFPQGVEIVVV 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 321 YNRSDLIQRATGTVNKALVEATVLVVILLLLFLGDLRAATVVAVTLPLAALTTFLLMRTFGLSANLMSLGGLAIAIGMLV 400
Cdd:pfam00873 320 YDTTPFIRASIEEVVKTLLEAIVLVILVMFLFLQNWRATLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGGLVLAIGLVV 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 401 DAAVVVVENTVERLDnpnIAGSRRLHAIYEAVAEVAAPVTSGVLIICLVFLPLLSLQGLEGKLFAPVALTIVFALGSSLL 480
Cdd:pfam00873 400 DDAIVVVENIERVLE---ENGLKPLEAAYKSMGEIGGALVAIALVLSAVFLPILFLGGLTGRIFRQFAITIVLAILLSVL 476
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 481 LSFTVIPVLASLLLKAHPHR-ESWIMRRIGPF-------YERQLARSLSRPKPVFAAAGGGMVLAAIAYVLIGKSFMPTM 552
Cdd:pfam00873 477 VALTLTPALCATLLKPRREPkHGGFFRWFNRMfdrltrgYAKLLAKVLRHTAVVLLVALLLVVGSVWLFVRIPTEFLPEE 556
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 553 DEGAILMQLAKLPSINLDASAKQDMAVQRAILaQVPEVKRIVARVGSDELGlDPMGLNETDSFLVLADRKDWRR--KDKA 630
Cdd:pfam00873 557 DEGVFVTSAQLPPGVSLDQTQRVMKQVEKILK-EKPEVESVFAVTGFAFSG-DNNGPNSGDAFISLKPWKERPGpeKSVQ 634
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 631 WLTEEIRKVAAQFPGVEATFTQPIEMRVSEMLTGSRGDLAVKVFGPDLQTLGDLAGRIEETLKKTRGASDVYTVAGDSVT 710
Cdd:pfam00873 635 ALIERLRKALKQIPGANVFLFQPIQLRGLGTISGFRSDLQVKIFGDDLDALDEARNQILAALAQLPGLSDVRSDGQEDQP 714
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 711 YLQLDVDRGAAVRAGLSAQALQQELRAQLEGAPAGVVFEQGKRTPILVRGPQDLREDPVLFEQAQIATPDGGVVRAGDVA 790
Cdd:pfam00873 715 QLQVNIDREKAARLGVSIQDINDTLSTALGGSYVNDFPEGGRVYDVVVQLPEDFRSSPEDIGQLYVRNPYGKMIPLSAFA 794
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 791 RIQRREGPVKIDRENASRFAVIQAYVQGRDLVGFVKEAQANVARDVPLPPGYRIAWGGQFENQKRAAARLGVVVPMALCL 870
Cdd:pfam00873 795 KIEWGYGPPSINRYNGFRSIVISGNVAAGDSLGDAMEAMAQIAKQVKLPPGYGYTWTGQFEQEQLAGNSLPILIALALLV 874
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 871 IFLVLFISLKSTRQSLLILANIPFAMIGGLVALWISGEYLSVPASVGLIALLGIAVLNGLVLVSHFNELV-QRGCDVATA 949
Cdd:pfam00873 875 VFLVLAALYESWSDPLSIMLTVPLALVGALLALWLRGLPNSVYAQVGLILLIGLAVKNAILMVEFANELReQEGKSLEEA 954
|
970 980 990 1000
....*....|....*....|....*....|....*....|....*..
gi 1243374125 950 VTEGARRRLRPVLMTASITALGLVPLLTATGPGSEIQRPLAIVVVGG 996
Cdd:pfam00873 955 ILEACRLRLRPILMTALAAILGVLPLALSTGAGSELQQPLGIVVFGG 1001
|
|
| 2A0601 |
TIGR00914 |
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation ... |
3-996 |
0e+00 |
|
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 129992 [Multi-domain] Cd Length: 1051 Bit Score: 803.59 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 3 KLIAFALSQRLLAAVLAIALVGLGANAFLKLPVDAFPDISPTQVKIILKAPGMTPEEVESQVITPLEMELLGIPKQAMLR 82
Cdd:TIGR00914 4 RIISFSVAQRWLVLLATLVMAILGIWSYNRLPIDAVPDITNVQVQINTSAPGYSPLEVEQRVTYPIETAMAGLPGLETTR 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 83 STAKYAIADLTIDFAPGTDVYWARQQTAERLSNALGALPAGVSGGLSPISTPLSDVFMFTIE---------GEGLTLEQK 153
Cdd:TIGR00914 84 SLSRYGLSQVTVIFKDGTDLYFARQLVNERLQQARDNLPEGVSPEMGPISTGLGEIFLYTVEaeegarkkdGGAYTLTDL 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 154 RTLLDWTVRPALRGLPGVADVNVLGGRAKTFEVSPDPAALAASGLTAQAIIDAIPASNRNDGSGRLSEGEEALVVRVAGA 233
Cdd:TIGR00914 164 RTIQDWIIRPQLRTVPGVAEVNSIGGYVKQFLVAPDPEKLAAYGLSLADVVNALERNNQNVGAGYIERRGEQYLVRAPGQ 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 234 ITSLDDLRDTAIALPSGGAARLGDLAEVSEGALTRYGAVTENGREEAVqAIVIALRGADAKAVVRSVEARLKELQPSLPK 313
Cdd:TIGR00914 244 VQSMDDIRNIVIATGEGVPIRIRDVARVQIGKELRTGAATENGKEVVL-GTVFMLIGENSRTVAQAVGDKLETINKTLPE 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 314 GVTVSPFYNRSDLIQRATGTVNKALVEATVLVVILLLLFLGDLRAATVVAVTLPLAALTTFLLMRTFGLSANLMSLGglA 393
Cdd:TIGR00914 323 GVEIVTTYDRSQLVDAAIATVKKNLLEGALLVIVILFLFLGNIRAALIAATVIPLSLLITFIGMVFQGISANLMSLG--A 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 394 IAIGMLVDAAVVVVENTVERLDNPNIAGSR------RLHAIYEAVAEVAAPVTSGVLIICLVFLPLLSLQGLEGKLFAPV 467
Cdd:TIGR00914 401 LDFGLIVDGAVVIVENAHRRLAEAQHHHGRqltlkeRLHEVFAASREVRRPLIFGQLIITLVFLPIFTLTGVEGKMFHPM 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 468 ALTIVFALGSSLLLSFTVIPVLASLLLKAH-PHRESWIMRRIGPFYERQLARSLSRPKPVFAAAGGGMVLAAIAYVLIGK 546
Cdd:TIGR00914 481 AFTVVLALAGAMILSLTFVPAAVALFIRGKvAEKENRLMRVLKRRYEPLLERVLAWPAVVLGAAAVSIVLVVWIASRVGG 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 547 SFMPTMDEGAILMQLAKLPSINLDASAKQDMAVQRAILaQVPEVKRIVARVGSDELGLDPMGLNETDSFLVLADRKDWR- 625
Cdd:TIGR00914 561 EFIPSLNEGDLAYQALRIPGTSLAQSVAMQQTLEKLIK-SFPEVARVFAKTGTAEIATDPMPPNASDTYIILKPESQWPe 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 626 -RKDKAWLTEEIRKVAAQFPGVEATFTQPIEMRVSEMLTGSRGDLAVKVFGPDLQTLGDLAGRIEETLKKTRGASDVYTV 704
Cdd:TIGR00914 640 gKKTKEDLIEEIQEATVRIPGNNYEFTQPIQMRFNELISGVRSDVAVKVFGDDLDDLDATAEKISAVLKGVPGAADVKVE 719
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 705 AGDSVTYLQLDVDRGAAVRAGLSAQALQQELRAQLEGAPAGVVFEQGKRTPILVRGPQDLREDPVLFEQAQIATPDGGVV 784
Cdd:TIGR00914 720 QTTGLPYLTVEIDREKAARYGLTVGDVQDTVATAVGGRMSGETFEGDRRFDIVIRLPESLRESPQALRQLPIPLPLSEDA 799
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 785 RA-----GDVARIQRREGPVKIDRENASRFAVIQAYVQGRDLVGFVKEAQANVARDVPLPPGYRIAWGGQFENQKRAAAR 859
Cdd:TIGR00914 800 RKqfiplSDVADLRVSPGPNQISRENGKRRVVVSANVRGRDLGSFVDDAKKAIAEQVKLPPGYWITWGGQFEQLQSATKR 879
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 860 LGVVVPMALCLIFLVLFISLKSTRQSLLILANIPFAMIGGLVALWISGEYLSVPASVGLIALLGIAVLNGLVLVSHFNEL 939
Cdd:TIGR00914 880 LQIVVPVTLLLIFVLLYAAFGNVKDALLVFTGIPFALTGGVFALWLRGIPLSISAAVGFIALSGVAVLNGLVMISFIRKL 959
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|....*..
gi 1243374125 940 VQRGCDVATAVTEGARRRLRPVLMTASITALGLVPLLTATGPGSEIQRPLAIVVVGG 996
Cdd:TIGR00914 960 LEEGPSLDEAVYEGALTRVRPVLMTALVASLGFVPMAIATGTGAEVQRPLATVVIGG 1016
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
25-996 |
2.53e-120 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 393.23 E-value: 2.53e-120
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 25 LGANAFLKLPVDAFPDISPTQVKIILKAPGMTPEEVESQVITPLEMELLGIPKQAMLRSTAKYAIADLTIDFAPGTDVYW 104
Cdd:NF033617 21 LGLLAFRKLPVREYPEVDFPTITVSTSYPGASPELMQSSITQPLEQQLAQIEGIDEMTSQSSLGYSTITLQFRLGTDLDV 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 105 ARQQTAERLSNALGALPAGVSgglSPIST----PLSDVFMF-TIEGEGLTLEQKRTLLDWTVRPALRGLPGVADVNVLGG 179
Cdd:NF033617 101 ALSEVQAAINAAQSLLPSEAP---DPPVYrkanSADTPIMYiGLTSEEMPRGQLTDYAERVLAPKLSQINGVGSVDVSGG 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 180 RAKTFEVSPDPAALAASGLTAQAIIDAIPASNRNDGSGRLSEGEEALVVRVAGAITSLDDLRDTAIALPSGGAA-RLGDL 258
Cdd:NF033617 178 QRPAMRVWLDPEKMAARGLTADDVRSALNSNNVNSPKGAVRGDSVVSTVRANDQLKTAEDYEDLVIKYADNGAPvRLGDV 257
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 259 AEVSEGALTRYGAVTENGREeAVQAIVIALRGADAKAVVRSVEARLKELQPSLPKGVTVSPFYNRSDLIQRATGTVNKAL 338
Cdd:NF033617 258 ATVELGAENVRNRAWANGVP-AVVLGINRQPGANPIEVADEIRALLPELQETLPKNIKVNVLYDRTRFIRASIDEVESTL 336
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 339 VEATVLVVILLLLFLGDLRAATVVAVTLPLAALTTFLLMRTFGLSANLMSLGGLAIAIGMLVDAAVVVVENTVERLDnpn 418
Cdd:NF033617 337 LEAVALVILVVFLFLRNLRATLIPAVTVPLSLIGTFAVMYLFGFSINLLTLMALVLAIGLVVDDAIVVVENIHRHIE--- 413
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 419 iAGSRRLHAIYEAVAEVAAPVTSGVLIICLVFLPLLSLQGLEGKLFAPVALTIVFALGSSLLLSFTVIPVLASLLLKAHP 498
Cdd:NF033617 414 -EGESPLEAALKGAREIGFTVIAMTLTLVAVYLPILFMGGLTGRLFREFAVTLAGAVIISGIVALTLTPMMCSRLLKANE 492
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 499 ------HRESWIMRRIGPFYERQLARSLSRPKPVFAAAGGGMVLAAIAYVLIGKSFMPTMDEGAILMQLAKLPSINLDA- 571
Cdd:NF033617 493 kpgrfaRAVDRFFDGLTARYGRGLKWVLKHRPLTLVVALATLALLPLLYVFIPKELAPSEDRGVIFGMIQAPQSISLDYm 572
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 572 SAKQDMAVQraILAQVPEV---KRIVARVGSDelgldpmGLNETDSFLVLADRKDwRRKDKAWLTEEIRKVAAQFPGVeA 648
Cdd:NF033617 573 SAKMRDVEK--ILSSDPEVqslTSFNGVGGNP-------GDNTGFGIINLKPWDE-RDVSAQEIIDRLRPKLAKVPGM-D 641
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 649 TFTQPiemrVSEMLTGSRGDLAVKVF---GPDLQTLGDLAGRIEETLKKTRGASDVYTVAGDSVTYLQLDVDRGAAVRAG 725
Cdd:NF033617 642 LFLFP----LQDLPGGAGSSLPQYQVtltPSDYDSLFTWAEKLKEKLRKSPQFADVDSDLQDKGPELNVDIDRDKAARLG 717
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 726 LSAQALQQELRAQLEGAPAGVVFEQGKRTPILVRGPQDLREDPVLFEQAQIATPDGGVVRAGDVARIQRREGPVKIDREN 805
Cdd:NF033617 718 ISMQDIGSTLEVAFGQRQVNTIYTDGNQYKVVLEVDRRYRLNPEALNQIYVRSNDGKLVPLSTLAKIEERAAPLSLNHFN 797
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 806 ASRFAVIQAYVQGRDLVGFVKEAQANVARDVpLPPGYRIAWGGQFENQKRAAARLGVVVPMALCLIFLVLFISLKSTRQS 885
Cdd:NF033617 798 QFNSATLSFNLAPGVSLGEAIEALDQAAKEL-LPSGISGSFQGAARAFQEEGSSLLFLFLLALAAIYLVLAIQYESFVDP 876
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 886 LLILANIPFAMIGGLVALWISGEYLSVPASVGLIALLGIAVLNGLVLVSHFNELVQR-GCDVATAVTEGARRRLRPVLMT 964
Cdd:NF033617 877 LTILSTVPLAGCGALLALALGGQSMNIYAQIGLITLIGLVKKNGILMVEFANELQRHqGLSRREAIYQAAALRLRPILMT 956
|
970 980 990
....*....|....*....|....*....|..
gi 1243374125 965 ASITALGLVPLLTATGPGSEIQRPLAIVVVGG 996
Cdd:NF033617 957 TLAMLLGAIPLMLSTGAGAESRFPLGIVIVGG 988
|
|
| PRK10555 |
PRK10555 |
multidrug efflux RND transporter permease AcrD; |
26-996 |
1.75e-62 |
|
multidrug efflux RND transporter permease AcrD;
Pssm-ID: 182544 [Multi-domain] Cd Length: 1037 Bit Score: 230.87 E-value: 1.75e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 26 GANAFLKLPVDAFPDISPTQVKIILKAPGMTPEEVESQVITPLEMELLGIPKQAMLRS-TAKYAIADLTIDFAPGTDVYW 104
Cdd:PRK10555 23 GTLAIFSLPVEQYPDLAPPNVRITANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSSqSSGTGQASVTLSFKAGTDPDE 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 105 ARQQTAERLSNALGALPAGV-SGGLSPISTPLSDVFMFTIEGEGLTLEqKRTLLDWT---VRPALRGLPGVADVNVLGGR 180
Cdd:PRK10555 103 AVQQVQNQLQSAMRKLPQAVqNQGVTVRKTGDTNILTIAFVSTDGSMD-KQDIADYVasnIQDPLSRVNGVGDIDAYGSQ 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 181 AkTFEVSPDPAALAASGLTAQAIIDAIPASNRNDGSGRL----SEGEEAL--VVRVAGAITSLDDLRDTAIAL-PSGGAA 253
Cdd:PRK10555 182 Y-SMRIWLDPAKLNSFQMTTKDVTDAIESQNAQIAVGQLggtpSVDKQALnaTINAQSLLQTPEQFRDITLRVnQDGSEV 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 254 RLGDLAEVSEGA-----LTRYgavteNGREEAVQAIVIAlRGADAKAVVRSVEARLKELQPSLPKGVTVSPFYNRSDLIQ 328
Cdd:PRK10555 261 TLGDVATVELGAekydyLSRF-----NGKPASGLGVKLA-SGANEMATAKLVLNRLDELAQYFPHGLEYKVAYETTSFVK 334
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 329 RATGTVNKALVEATVLVVILLLLFLGDLRAATVVAVTLPLAALTTFLLMRTFGLSANLMSLGGLAIAIGMLVDAAVVVVE 408
Cdd:PRK10555 335 ASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSINTLTMFAMVLAIGLLVDDAIVVVE 414
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 409 NtVERLD-----NPNIAGSRRLHAIYEAVAEVAapvtsgvLIICLVFLPLLSLQGLEGKLFAPVALTIVFALGSSLLLSF 483
Cdd:PRK10555 415 N-VERIMseeglTPREATRKSMGQIQGALVGIA-------MVLSAVFVPMAFFGGTTGAIYRQFSITIVSAMVLSVLVAM 486
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 484 TVIPVLASLLLK----AHPHRE----SWIMR---RIGPFYERQLARSLSRPKP---VFAAAGGGMVLaaiAYVLIGKSFM 549
Cdd:PRK10555 487 ILTPALCATLLKplkkGEHHGQkgffGWFNRmfnRNAERYEKGVAKILHRSLRwilIYVLLLGGMVF---LFLRLPTSFL 563
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 550 PTMDEGAILMQLaKLPSinlDASAKQDMAV-----QRAILAQVPEVKRIVARVGSDELGldpMGLNETDSFLVLadrKDW 624
Cdd:PRK10555 564 PLEDRGMFTTSV-QLPS---GSTQQQTLKVvekveKYYFTHEKDNVMSVFATVGSGPGG---NGQNVARMFIRL---KDW 633
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 625 RRKDKAwlteeIRKVAAQFPGVEATFTQPIEMRVSEMLTGSRGDLAVKVfGPDLQtLGDLAG-----------RIEETLK 693
Cdd:PRK10555 634 DERDSK-----TGTSFAIIERATKAFNKIKEARVIASSPPAISGLGSSA-GFDME-LQDHAGaghdalmaarnQLLALAA 706
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 694 KTRGASDVYTVAGDSVTYLQLDVDRGAAVRAGLSAQALQQELRAQLEGAPAGVVFEQGKRTPILVRGPQDLREDPVLFEQ 773
Cdd:PRK10555 707 KNPELTRVRHNGLDDSPQLQIDIDQRKAQALGVSIDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAPYRMLPDDINL 786
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 774 AQIATPDGGVVRAGDVARIQRREGPVKIDRENasrfaviqayvqGRDLVGFVKEAQANV----ARDV------PLPPGYR 843
Cdd:PRK10555 787 WYVRNKDGGMVPFSAFATSRWETGSPRLERYN------------GYSAVEIVGEAAPGVstgtAMDImeslvkQLPNGFG 854
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 844 IAWGGQFENQKRAAARLGVVVPMALCLIFLVLFISLKSTRQSLLILANIPFAMIGGLVALWISGEYLSVPASVGLIALLG 923
Cdd:PRK10555 855 LEWTAMSYQERLSGAQAPALYAISLLVVFLCLAALYESWSVPFSVMLVVPLGVIGALLATWMRGLENDVYFQVGLLTVIG 934
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1243374125 924 IAVLNGLVLVSHFNELVQRGCDVATAVTEGARRRLRPVLMTASITALGLVPLLTATGPGSEIQRPLAIVVVGG 996
Cdd:PRK10555 935 LSAKNAILIVEFANEMNQKGHDLFEATLHASRQRLRPILMTSLAFIFGVLPMATSTGAGSGSQHAVGTGVMGG 1007
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| CusA |
COG3696 |
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism]; |
1-996 |
0e+00 |
|
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
Pssm-ID: 442911 [Multi-domain] Cd Length: 1031 Bit Score: 1258.40 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 1 MRKLIAFALSQRLLAAVLAIALVGLGANAFLKLPVDAFPDISPTQVKIILKAPGMTPEEVESQVITPLEMELLGIPKQAM 80
Cdd:COG3696 2 LNRIIRFSLRNRLLVLLLTLLLAAAGIYSLRRLPIDAFPDITNVQVQVITEAPGLSPEEVEQQVTYPIETALNGLPGVKE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 81 LRSTAKYAIADLTIDFAPGTDVYWARQQTAERLSNALGALPAGVSGGLSPISTPLSDVFMFTIEGEG--LTLEQKRTLLD 158
Cdd:COG3696 82 VRSISRFGLSVVTVIFEDGTDIYWARQLVLERLQQVREQLPAGVTPELGPISTGLGEIYQYTLESDPgkYSLMELRTLQD 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 159 WTVRPALRGLPGVADVNVLGGRAKTFEVSPDPAALAASGLTAQAIIDAIPASNRNDGSGRLSEGEEALVVRVAGAITSLD 238
Cdd:COG3696 162 WVIRPQLRSVPGVAEVNSFGGFVKQYQVLVDPAKLRAYGLTLDDVIEALERNNANVGGGYIERGGQEYLVRGIGLIRSLE 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 239 DLRDTAIALPSGGAARLGDLAEVSEGALTRYGAVTENGREEAVQAIVIALRGADAKAVVRSVEARLKELQPSLPKGVTVS 318
Cdd:COG3696 242 DIENIVVKTRNGTPVLLRDVAEVRIGPAPRRGAATLNGEGEVVGGIVLMLKGENALEVIEAVKAKLAELKPSLPEGVKIV 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 319 PFYNRSDLIQRATGTVNKALVEATVLVVILLLLFLGDLRAATVVAVTLPLAALTTFLLMRTFGLSANLMSLGGLAIAIGM 398
Cdd:COG3696 322 PFYDRSDLIDRAIHTVTKNLLEGALLVILVLFLFLGNLRAALIVALAIPLSLLFAFIVMRLFGISANLMSLGGLAIDFGI 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 399 LVDAAVVVVENTVERLDNPNIAGSR--RLHAIYEAVAEVAAPVTSGVLIICLVFLPLLSLQGLEGKLFAPVALTIVFALG 476
Cdd:COG3696 402 IVDGAVVMVENILRRLEENRAAGTPreRLEVVLEAAREVRRPIFFATLIIILVFLPIFTLEGVEGKLFRPMALTVIFALL 481
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 477 SSLLLSFTVIPVLASLLLK-AHPHRESWIMRRIGPFYERQLARSLSRPKPVFAAAGGGMVLAAIAYVLIGKSFMPTMDEG 555
Cdd:COG3696 482 GALLLSLTLVPVLASLLLRgKVPEKENPLVRWLKRLYRPLLRWALRHPKLVLAVALVLLVLALALFPRLGSEFLPELDEG 561
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 556 AILMQLAKLPSINLDASAKQDMAVQRaILAQVPEVKRIVARVGSDELGLDPMGLNETDSFLVLADRKDWRR-KDKAWLTE 634
Cdd:COG3696 562 DLLVMATLPPGISLEESVELGQQVER-ILKSFPEVESVVSRTGRAEDATDPMGVNMSETFVILKPRSEWRSgRTKEELIA 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 635 EIRKVAAQFPGVEATFTQPIEMRVSEMLTGSRGDLAVKVFGPDLQTLGDLAGRIEETLKKTRGASDVYTVAGDSVTYLQL 714
Cdd:COG3696 641 EMREALEQIPGVNFNFSQPIQMRVDELLSGVRADVAVKIFGDDLDVLRRLAEQIEAVLKTVPGAADVQVERVTGLPQLDI 720
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 715 DVDRGAAVRAGLSAQALQQELRAQLEGAPAGVVFEQGKRTPILVRGPQDLREDPVLFEQAQIATPDGGVVRAGDVARIQR 794
Cdd:COG3696 721 RIDRDAAARYGLNVADVQDVVETAIGGKAVGQVYEGERRFDIVVRLPEELRDDPEAIRNLPIPTPSGAQVPLSQVADIEV 800
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 795 REGPVKIDRENASRFAVIQAYVQGRDLVGFVKEAQANVARDVPLPPGYRIAWGGQFENQKRAAARLGVVVPMALCLIFLV 874
Cdd:COG3696 801 VEGPNQISRENGRRRIVVQANVRGRDLGSFVAEAQAKVAEQVKLPPGYYIEWGGQFENLQRATARLAIVVPLALLLIFLL 880
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 875 LFISLKSTRQSLLILANIPFAMIGGLVALWISGEYLSVPASVGLIALLGIAVLNGLVLVSHFNELVQRGCDVATAVTEGA 954
Cdd:COG3696 881 LYLAFGSVRDALLILLNVPFALIGGVLALWLRGMPLSVSAGVGFIALFGVAVLNGVVLVSYINQLRAEGLDLREAIIEGA 960
|
970 980 990 1000
....*....|....*....|....*....|....*....|..
gi 1243374125 955 RRRLRPVLMTASITALGLVPLLTATGPGSEIQRPLAIVVVGG 996
Cdd:COG3696 961 LERLRPVLMTALVAALGLLPMALSTGPGSEVQRPLATVVIGG 1002
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
4-996 |
0e+00 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 813.84 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 4 LIAFALSQRLLAAVLAIALVGLGANAFLKLPVDAFPDISPTQVKIILKAPGMTPEEVESQVITPLEMELLGIPKQAMLRS 83
Cdd:pfam00873 1 MSKFFIRRPIFTLVLAIAILLAGILSFFSLPVDAFPEIAPPTVQVSTSYPGASPEEVEDTVTQPIEQAMNGLDGLKYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 84 TAKYAIADLTIDFAPGTDVYWARQQTAERLSNALGALPAGVS-GGLSPISTPLSDVFMFTIEGEG--LTLEQKRTLLDWT 160
Cdd:pfam00873 81 QSSYGLSSITLTFELGTDIDIARQDVQNRLQLATPLLPEGVQrPGISVIKTSLGPIMVLAVTSPDgsYTQTDLRDYADTN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 161 VRPALRGLPGVADVNVLGGRAKTFEVSPDPAALAASGLTAQAIIDAIPASNRNDGSGRLSEGEEALVVRVAGAITSLDDL 240
Cdd:pfam00873 161 IKPQLSRVPGVGDVQLFGGSEYAMRIWLDPQKLARYGLTLTDVVSALKEQNVNIGAGQLEGQGLQALIRAQGQLQSAEDF 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 241 RDTAIALPSGGAARLGDLAEVSEGALTRYGAVTENGrEEAVQAIVIALRGADAKAVVRSVEARLKELQPSLPKGVTVSPF 320
Cdd:pfam00873 241 EKIIVKNQDGSPVRLRDVATVELGSELYRGFATFNG-KPAVGLGVQKLPGANAIETADAVRAKLAELKPTFPQGVEIVVV 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 321 YNRSDLIQRATGTVNKALVEATVLVVILLLLFLGDLRAATVVAVTLPLAALTTFLLMRTFGLSANLMSLGGLAIAIGMLV 400
Cdd:pfam00873 320 YDTTPFIRASIEEVVKTLLEAIVLVILVMFLFLQNWRATLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGGLVLAIGLVV 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 401 DAAVVVVENTVERLDnpnIAGSRRLHAIYEAVAEVAAPVTSGVLIICLVFLPLLSLQGLEGKLFAPVALTIVFALGSSLL 480
Cdd:pfam00873 400 DDAIVVVENIERVLE---ENGLKPLEAAYKSMGEIGGALVAIALVLSAVFLPILFLGGLTGRIFRQFAITIVLAILLSVL 476
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 481 LSFTVIPVLASLLLKAHPHR-ESWIMRRIGPF-------YERQLARSLSRPKPVFAAAGGGMVLAAIAYVLIGKSFMPTM 552
Cdd:pfam00873 477 VALTLTPALCATLLKPRREPkHGGFFRWFNRMfdrltrgYAKLLAKVLRHTAVVLLVALLLVVGSVWLFVRIPTEFLPEE 556
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 553 DEGAILMQLAKLPSINLDASAKQDMAVQRAILaQVPEVKRIVARVGSDELGlDPMGLNETDSFLVLADRKDWRR--KDKA 630
Cdd:pfam00873 557 DEGVFVTSAQLPPGVSLDQTQRVMKQVEKILK-EKPEVESVFAVTGFAFSG-DNNGPNSGDAFISLKPWKERPGpeKSVQ 634
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 631 WLTEEIRKVAAQFPGVEATFTQPIEMRVSEMLTGSRGDLAVKVFGPDLQTLGDLAGRIEETLKKTRGASDVYTVAGDSVT 710
Cdd:pfam00873 635 ALIERLRKALKQIPGANVFLFQPIQLRGLGTISGFRSDLQVKIFGDDLDALDEARNQILAALAQLPGLSDVRSDGQEDQP 714
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 711 YLQLDVDRGAAVRAGLSAQALQQELRAQLEGAPAGVVFEQGKRTPILVRGPQDLREDPVLFEQAQIATPDGGVVRAGDVA 790
Cdd:pfam00873 715 QLQVNIDREKAARLGVSIQDINDTLSTALGGSYVNDFPEGGRVYDVVVQLPEDFRSSPEDIGQLYVRNPYGKMIPLSAFA 794
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 791 RIQRREGPVKIDRENASRFAVIQAYVQGRDLVGFVKEAQANVARDVPLPPGYRIAWGGQFENQKRAAARLGVVVPMALCL 870
Cdd:pfam00873 795 KIEWGYGPPSINRYNGFRSIVISGNVAAGDSLGDAMEAMAQIAKQVKLPPGYGYTWTGQFEQEQLAGNSLPILIALALLV 874
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 871 IFLVLFISLKSTRQSLLILANIPFAMIGGLVALWISGEYLSVPASVGLIALLGIAVLNGLVLVSHFNELV-QRGCDVATA 949
Cdd:pfam00873 875 VFLVLAALYESWSDPLSIMLTVPLALVGALLALWLRGLPNSVYAQVGLILLIGLAVKNAILMVEFANELReQEGKSLEEA 954
|
970 980 990 1000
....*....|....*....|....*....|....*....|....*..
gi 1243374125 950 VTEGARRRLRPVLMTASITALGLVPLLTATGPGSEIQRPLAIVVVGG 996
Cdd:pfam00873 955 ILEACRLRLRPILMTALAAILGVLPLALSTGAGSELQQPLGIVVFGG 1001
|
|
| 2A0601 |
TIGR00914 |
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation ... |
3-996 |
0e+00 |
|
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 129992 [Multi-domain] Cd Length: 1051 Bit Score: 803.59 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 3 KLIAFALSQRLLAAVLAIALVGLGANAFLKLPVDAFPDISPTQVKIILKAPGMTPEEVESQVITPLEMELLGIPKQAMLR 82
Cdd:TIGR00914 4 RIISFSVAQRWLVLLATLVMAILGIWSYNRLPIDAVPDITNVQVQINTSAPGYSPLEVEQRVTYPIETAMAGLPGLETTR 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 83 STAKYAIADLTIDFAPGTDVYWARQQTAERLSNALGALPAGVSGGLSPISTPLSDVFMFTIE---------GEGLTLEQK 153
Cdd:TIGR00914 84 SLSRYGLSQVTVIFKDGTDLYFARQLVNERLQQARDNLPEGVSPEMGPISTGLGEIFLYTVEaeegarkkdGGAYTLTDL 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 154 RTLLDWTVRPALRGLPGVADVNVLGGRAKTFEVSPDPAALAASGLTAQAIIDAIPASNRNDGSGRLSEGEEALVVRVAGA 233
Cdd:TIGR00914 164 RTIQDWIIRPQLRTVPGVAEVNSIGGYVKQFLVAPDPEKLAAYGLSLADVVNALERNNQNVGAGYIERRGEQYLVRAPGQ 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 234 ITSLDDLRDTAIALPSGGAARLGDLAEVSEGALTRYGAVTENGREEAVqAIVIALRGADAKAVVRSVEARLKELQPSLPK 313
Cdd:TIGR00914 244 VQSMDDIRNIVIATGEGVPIRIRDVARVQIGKELRTGAATENGKEVVL-GTVFMLIGENSRTVAQAVGDKLETINKTLPE 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 314 GVTVSPFYNRSDLIQRATGTVNKALVEATVLVVILLLLFLGDLRAATVVAVTLPLAALTTFLLMRTFGLSANLMSLGglA 393
Cdd:TIGR00914 323 GVEIVTTYDRSQLVDAAIATVKKNLLEGALLVIVILFLFLGNIRAALIAATVIPLSLLITFIGMVFQGISANLMSLG--A 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 394 IAIGMLVDAAVVVVENTVERLDNPNIAGSR------RLHAIYEAVAEVAAPVTSGVLIICLVFLPLLSLQGLEGKLFAPV 467
Cdd:TIGR00914 401 LDFGLIVDGAVVIVENAHRRLAEAQHHHGRqltlkeRLHEVFAASREVRRPLIFGQLIITLVFLPIFTLTGVEGKMFHPM 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 468 ALTIVFALGSSLLLSFTVIPVLASLLLKAH-PHRESWIMRRIGPFYERQLARSLSRPKPVFAAAGGGMVLAAIAYVLIGK 546
Cdd:TIGR00914 481 AFTVVLALAGAMILSLTFVPAAVALFIRGKvAEKENRLMRVLKRRYEPLLERVLAWPAVVLGAAAVSIVLVVWIASRVGG 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 547 SFMPTMDEGAILMQLAKLPSINLDASAKQDMAVQRAILaQVPEVKRIVARVGSDELGLDPMGLNETDSFLVLADRKDWR- 625
Cdd:TIGR00914 561 EFIPSLNEGDLAYQALRIPGTSLAQSVAMQQTLEKLIK-SFPEVARVFAKTGTAEIATDPMPPNASDTYIILKPESQWPe 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 626 -RKDKAWLTEEIRKVAAQFPGVEATFTQPIEMRVSEMLTGSRGDLAVKVFGPDLQTLGDLAGRIEETLKKTRGASDVYTV 704
Cdd:TIGR00914 640 gKKTKEDLIEEIQEATVRIPGNNYEFTQPIQMRFNELISGVRSDVAVKVFGDDLDDLDATAEKISAVLKGVPGAADVKVE 719
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 705 AGDSVTYLQLDVDRGAAVRAGLSAQALQQELRAQLEGAPAGVVFEQGKRTPILVRGPQDLREDPVLFEQAQIATPDGGVV 784
Cdd:TIGR00914 720 QTTGLPYLTVEIDREKAARYGLTVGDVQDTVATAVGGRMSGETFEGDRRFDIVIRLPESLRESPQALRQLPIPLPLSEDA 799
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 785 RA-----GDVARIQRREGPVKIDRENASRFAVIQAYVQGRDLVGFVKEAQANVARDVPLPPGYRIAWGGQFENQKRAAAR 859
Cdd:TIGR00914 800 RKqfiplSDVADLRVSPGPNQISRENGKRRVVVSANVRGRDLGSFVDDAKKAIAEQVKLPPGYWITWGGQFEQLQSATKR 879
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 860 LGVVVPMALCLIFLVLFISLKSTRQSLLILANIPFAMIGGLVALWISGEYLSVPASVGLIALLGIAVLNGLVLVSHFNEL 939
Cdd:TIGR00914 880 LQIVVPVTLLLIFVLLYAAFGNVKDALLVFTGIPFALTGGVFALWLRGIPLSISAAVGFIALSGVAVLNGLVMISFIRKL 959
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|....*..
gi 1243374125 940 VQRGCDVATAVTEGARRRLRPVLMTASITALGLVPLLTATGPGSEIQRPLAIVVVGG 996
Cdd:TIGR00914 960 LEEGPSLDEAVYEGALTRVRPVLMTALVASLGFVPMAIATGTGAEVQRPLATVVIGG 1016
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
25-996 |
0e+00 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 689.92 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 25 LGANAFLKLPVDAFPDISPTQVKIILKAPGMTPEEVESQVITPLEMELLGIPKQAMLRSTAKYAIADLTIDFAPGTDVYW 104
Cdd:COG0841 24 AGLLAYLRLPVEQFPDIDPPTVTVSTTYPGASPEEVESTVTTPIEEALNGVEGIKYITSTSSEGSSSITVEFELGTDIDE 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 105 ARQQTAERLSNALGALPAGVSG-GLSPISTPLSDVFMFTIEGEGLTLEQKRTLLDWTVRPALRGLPGVADVNVLGGRAKT 183
Cdd:COG0841 104 ALVDVQNAVDRARSDLPEDVEPpGVTKVNPSDFPVMVLALSSDDLDELELSDYAERNIKDRLERVPGVGQVQIFGGRERE 183
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 184 FEVSPDPAALAASGLTAQAIIDAIPASNRNDGSGRLSEGEEALVVRVAGAITSLDDLRDTAIALPSGGAARLGDLAEVSE 263
Cdd:COG0841 184 IRIWLDPDKLAAYGLTLADVANAIRAQNVDVPAGRIGGGDREYTVRTNGRLKTPEEFENIVIRTNDGSVVRLGDVARVED 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 264 GALTRYGAVTENGREeAVQAIVIALRGADAKAVVRSVEARLKELQPSLPKGVTVSPFYNRSDLIQRATGTVNKALVEATV 343
Cdd:COG0841 264 GAEDYRSIARLNGKP-AVGLAIQKQPGANALEVADAVRAKLEELQASLPEGVELTIVYDQSEFIRASIEEVVKTLLEAIL 342
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 344 LVVILLLLFLGDLRAATVVAVTLPLAALTTFLLMRTFGLSANLMSLGGLAIAIGMLVDAAVVVVENTVERLDNpniaGSR 423
Cdd:COG0841 343 LVVLVVFLFLRSWRATLIPAVAIPVSLIGTFAVMYLLGFSLNILTLFALVLAIGIVVDDAIVVVENIERHMEE----GLS 418
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 424 RLHAIYEAVAEVAAPVTSGVLIICLVFLPLLSLQGLEGKLFAPVALTIVFALGSSLLLSFTVIPVLASLLLKAHPH-RES 502
Cdd:COG0841 419 PLEAAIKGAREVAGAVIASTLTLVAVFLPLAFMGGITGQLFRQFALTVAIALLISLFVALTLTPALCARLLKPHPKgKKG 498
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 503 WIMRRIGPF-------YERQLARSLSRPKPVFAAAGGGMVLAAIAYVLIGKSFMPTMDEGAILMQLAKLPSINLDASAKQ 575
Cdd:COG0841 499 RFFRAFNRGfdrltrgYGRLLRWALRHRKLTLLVALALLALSVLLFGRLPTEFFPEEDQGQIIVSVQLPPGTSLERTEAV 578
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 576 DMAVQrAILAQVPEVKRIVARVGSdelGLDPMGLNETDSFLVLADRKDwRRKDKAWLTEEIRKVAAQFPGVEATFTQPie 655
Cdd:COG0841 579 VRQVE-EILLEVPEVESVFSVVGF---SGGGSGSNSGTIFVTLKPWDE-RDRSADEIIARLREKLAKIPGARVFVFQP-- 651
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 656 mrvSEMLTGSRGDLAVKVFGPDLQTLGDLAGRIEETLKKTRGASDVYTVAGDSVTYLQLDVDRGAAVRAGLSAQALQQEL 735
Cdd:COG0841 652 ---PAGGLGSGAPIEVQLQGDDLEELAAAAEKLLAALRQIPGLVDVRSDLQLGKPELQLDIDREKAAALGVTVADVASTL 728
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 736 RAQLEGAPAGVVFEQGKRTPILVRGPQDLREDPVLFEQAQIATPDGGVVRAGDVARIQRREGPVKIDRENASRFAVIQAY 815
Cdd:COG0841 729 RAALGGRYVNDFNRGGREYDVRVQAPEEDRNSPEDLENLYVRTPDGEMVPLSSVATIEEGTGPSSINRYNGQRSVTVSAN 808
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 816 V-QGRDLVGFVKEAQAnVARDVPLPPGYRIAWGGQFENQKRAAARLGVVVPMALCLIFLVLFISLKSTRQSLLILANIPF 894
Cdd:COG0841 809 LaPGVSLGEALAAIEE-LAAELKLPPGVSIEFTGQAEEEQESFSSLGLAFLLALLLVYLVLAAQFESFIQPLIILLTVPL 887
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 895 AMIGGLVALWISGEYLSVPASVGLIALLGIAVLNGLVLVSHFNELVQRGCDVATAVTEGARRRLRPVLMTASITALGLVP 974
Cdd:COG0841 888 ALIGALLGLLLTGTPLNIYSQIGLIMLIGIVVKNAILLVDFANQLREEGMSLREAILEAARLRLRPILMTSLATILGLLP 967
|
970 980
....*....|....*....|..
gi 1243374125 975 LLTATGPGSEIQRPLAIVVVGG 996
Cdd:COG0841 968 LALGTGAGAEFRQPLGIAVIGG 989
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
25-996 |
2.53e-120 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 393.23 E-value: 2.53e-120
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 25 LGANAFLKLPVDAFPDISPTQVKIILKAPGMTPEEVESQVITPLEMELLGIPKQAMLRSTAKYAIADLTIDFAPGTDVYW 104
Cdd:NF033617 21 LGLLAFRKLPVREYPEVDFPTITVSTSYPGASPELMQSSITQPLEQQLAQIEGIDEMTSQSSLGYSTITLQFRLGTDLDV 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 105 ARQQTAERLSNALGALPAGVSgglSPIST----PLSDVFMF-TIEGEGLTLEQKRTLLDWTVRPALRGLPGVADVNVLGG 179
Cdd:NF033617 101 ALSEVQAAINAAQSLLPSEAP---DPPVYrkanSADTPIMYiGLTSEEMPRGQLTDYAERVLAPKLSQINGVGSVDVSGG 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 180 RAKTFEVSPDPAALAASGLTAQAIIDAIPASNRNDGSGRLSEGEEALVVRVAGAITSLDDLRDTAIALPSGGAA-RLGDL 258
Cdd:NF033617 178 QRPAMRVWLDPEKMAARGLTADDVRSALNSNNVNSPKGAVRGDSVVSTVRANDQLKTAEDYEDLVIKYADNGAPvRLGDV 257
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 259 AEVSEGALTRYGAVTENGREeAVQAIVIALRGADAKAVVRSVEARLKELQPSLPKGVTVSPFYNRSDLIQRATGTVNKAL 338
Cdd:NF033617 258 ATVELGAENVRNRAWANGVP-AVVLGINRQPGANPIEVADEIRALLPELQETLPKNIKVNVLYDRTRFIRASIDEVESTL 336
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 339 VEATVLVVILLLLFLGDLRAATVVAVTLPLAALTTFLLMRTFGLSANLMSLGGLAIAIGMLVDAAVVVVENTVERLDnpn 418
Cdd:NF033617 337 LEAVALVILVVFLFLRNLRATLIPAVTVPLSLIGTFAVMYLFGFSINLLTLMALVLAIGLVVDDAIVVVENIHRHIE--- 413
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 419 iAGSRRLHAIYEAVAEVAAPVTSGVLIICLVFLPLLSLQGLEGKLFAPVALTIVFALGSSLLLSFTVIPVLASLLLKAHP 498
Cdd:NF033617 414 -EGESPLEAALKGAREIGFTVIAMTLTLVAVYLPILFMGGLTGRLFREFAVTLAGAVIISGIVALTLTPMMCSRLLKANE 492
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 499 ------HRESWIMRRIGPFYERQLARSLSRPKPVFAAAGGGMVLAAIAYVLIGKSFMPTMDEGAILMQLAKLPSINLDA- 571
Cdd:NF033617 493 kpgrfaRAVDRFFDGLTARYGRGLKWVLKHRPLTLVVALATLALLPLLYVFIPKELAPSEDRGVIFGMIQAPQSISLDYm 572
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 572 SAKQDMAVQraILAQVPEV---KRIVARVGSDelgldpmGLNETDSFLVLADRKDwRRKDKAWLTEEIRKVAAQFPGVeA 648
Cdd:NF033617 573 SAKMRDVEK--ILSSDPEVqslTSFNGVGGNP-------GDNTGFGIINLKPWDE-RDVSAQEIIDRLRPKLAKVPGM-D 641
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 649 TFTQPiemrVSEMLTGSRGDLAVKVF---GPDLQTLGDLAGRIEETLKKTRGASDVYTVAGDSVTYLQLDVDRGAAVRAG 725
Cdd:NF033617 642 LFLFP----LQDLPGGAGSSLPQYQVtltPSDYDSLFTWAEKLKEKLRKSPQFADVDSDLQDKGPELNVDIDRDKAARLG 717
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 726 LSAQALQQELRAQLEGAPAGVVFEQGKRTPILVRGPQDLREDPVLFEQAQIATPDGGVVRAGDVARIQRREGPVKIDREN 805
Cdd:NF033617 718 ISMQDIGSTLEVAFGQRQVNTIYTDGNQYKVVLEVDRRYRLNPEALNQIYVRSNDGKLVPLSTLAKIEERAAPLSLNHFN 797
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 806 ASRFAVIQAYVQGRDLVGFVKEAQANVARDVpLPPGYRIAWGGQFENQKRAAARLGVVVPMALCLIFLVLFISLKSTRQS 885
Cdd:NF033617 798 QFNSATLSFNLAPGVSLGEAIEALDQAAKEL-LPSGISGSFQGAARAFQEEGSSLLFLFLLALAAIYLVLAIQYESFVDP 876
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 886 LLILANIPFAMIGGLVALWISGEYLSVPASVGLIALLGIAVLNGLVLVSHFNELVQR-GCDVATAVTEGARRRLRPVLMT 964
Cdd:NF033617 877 LTILSTVPLAGCGALLALALGGQSMNIYAQIGLITLIGLVKKNGILMVEFANELQRHqGLSRREAIYQAAALRLRPILMT 956
|
970 980 990
....*....|....*....|....*....|..
gi 1243374125 965 ASITALGLVPLLTATGPGSEIQRPLAIVVVGG 996
Cdd:NF033617 957 TLAMLLGAIPLMLSTGAGAESRFPLGIVIVGG 988
|
|
| 2A0602 |
TIGR00915 |
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins ... |
24-996 |
1.57e-82 |
|
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 273335 [Multi-domain] Cd Length: 1044 Bit Score: 289.71 E-value: 1.57e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 24 GLGANAFLKLPVDAFPDISPTQVKIILKAPGMTPEEVESQVITPLEMELLGIPK-QAMLRSTAKYAIADLTIDFAPGTDV 102
Cdd:TIGR00915 21 LAGTLSILSLPVSQYPSIAPPAITVSASYPGASAQTVQDTVTQVIEQNMNGIDGlRYMSSSSDSDGSMTITLTFEQGTDP 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 103 YWARQQTAERLSNALGALPA-----GVSggLSPISTPLSDVFMFTIEGEGLTLEQKRTLLDWTVRPALRGLPGVADVNVL 177
Cdd:TIGR00915 101 DIAQVQVQNKLQLATPLLPQevqrqGVR--VEKASSNFLMVIGLVSDDGSMTKEDLSDYAASNMVDPLSRLEGVGDVQLF 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 178 GGRaKTFEVSPDPAALAASGLTAQAIIDAIPASNRNDGSGRLS-----EGEE-ALVVRVAGAITSLDDLRDTAI-ALPSG 250
Cdd:TIGR00915 179 GSQ-YAMRIWLDPAKLNSYQLTPADVISAISAQNAQISAGQLGglpavPGQQlNATIIAQTRLQTPEQFENILLkVNTDG 257
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 251 GAARLGDLAEVSEGAlTRYGAVTE-NGREEAVQAIVIALrGADAKAVVRSVEARLKELQPSLPKGVTVSPFYNRSDLIQR 329
Cdd:TIGR00915 258 SQVRLKDVARVELGG-ENYSISARfNGKPASGLAIKLAT-GANALDTAKAVKAELAVLEPFFPQGMKYVYPYDTTPFVEA 335
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 330 ATGTVNKALVEATVLVVILLLLFLGDLRAATVVAVTLPLAALTTFLLMRTFGLSANLMSLGGLAIAIGMLVDAAVVVVEN 409
Cdd:TIGR00915 336 SIEEVVHTLIEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFAMVLAIGLLVDDAIVVVEN 415
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 410 tVERL-----DNPNIAGSRRLHAIYEAVAEVAapvtsgvLIICLVFLPLLSLQGLEGKLFAPVALTIVFALGSSLLLSFT 484
Cdd:TIGR00915 416 -VERVmaeegLPPKEATRKSMGQIQGALVGIA-------MVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMALSVLVALI 487
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 485 VIPVLASLLLKAHPHRE---------SWIMR---RIGPFYERQLARSLSRPKP---VFAAAGGGMVLaaiAYVLIGKSFM 549
Cdd:TIGR00915 488 LTPALCATMLKPIEKGEhhekkggffGWFNRmfdSSTHGYENGVGKILRRRGRyllVYVLLVGGMVF---LFVRLPTSFL 564
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 550 PTMDEGaILMQLAKLPSinlDASAKQDMAVqraiLAQV---------PEVKRIVARVGSDELGldpMGLNETDSFLVLad 620
Cdd:TIGR00915 565 PDEDQG-VFMTIVQLPA---GATAERTQAV----LAQVtkyllakekANVESVFTVNGFSFAG---RGQNMGMAFIRL-- 631
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 621 rKDWRRKDKAWLTEE--IRKVAAQFPGVEATFTQPIEM-RVSEMLTGSrgdlavkvfGPDLQtLGDLAGRIEETLKKTRG 697
Cdd:TIGR00915 632 -KDWEERTGKENSVFaiAGRATGHFMQIKDAMVIAFVPpAILELGNAT---------GFDFF-LQDRAGLGHEALLQARN 700
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 698 A-----------SDVYTVAGDSVTYLQLDVDRGAAVRAGLSAQALQQELRAQLEGAPAGVVFEQGKRTPILVRGPQDLRE 766
Cdd:TIGR00915 701 QllglaaqnpalTRVRPNGLEDEPQLKIDIDREKAQALGVSIADINTTLSTAWGSSYVNDFIDRGRVKRVYVQAEEDARM 780
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 767 DPVLFEQAQIATPDGGVVRAGDVARIQRREGPVKIDRENASRFAVIQAYVQGRDLVGFVKEAQANVARDvpLPPGYRIAW 846
Cdd:TIGR00915 781 SPEDINKWYVRNASGEMVPFSAFATVRWEYGSPQLERYNGLPSMEILGSAAPGVSTGQAMAAMEAIAQK--LPPGFGFSW 858
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 847 GGQFENQKRAAARLGVVVPMALCLIFLVLFISLKSTRQSLLILANIPFAMIGGLVALWISGEYLSVPASVGLIALLGIAV 926
Cdd:TIGR00915 859 TGMSYEERLSGSQAPALYALSLLVVFLCLAALYESWSIPVSVMLVVPLGIIGALLATTLRGLSNDVYFQVGLLTTIGLSA 938
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 927 LNGLVLVSHFNELVQRGCDVATAVTEGARRRLRPVLMTASITALGLVPLLTATGPGSEIQRPLAIVVVGG 996
Cdd:TIGR00915 939 KNAILIVEFAKELMAQGKSIVEAALEAARLRLRPILMTSLAFILGVVPLAISTGAGSGSQHAIGTGVFGG 1008
|
|
| PRK10555 |
PRK10555 |
multidrug efflux RND transporter permease AcrD; |
26-996 |
1.75e-62 |
|
multidrug efflux RND transporter permease AcrD;
Pssm-ID: 182544 [Multi-domain] Cd Length: 1037 Bit Score: 230.87 E-value: 1.75e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 26 GANAFLKLPVDAFPDISPTQVKIILKAPGMTPEEVESQVITPLEMELLGIPKQAMLRS-TAKYAIADLTIDFAPGTDVYW 104
Cdd:PRK10555 23 GTLAIFSLPVEQYPDLAPPNVRITANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSSqSSGTGQASVTLSFKAGTDPDE 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 105 ARQQTAERLSNALGALPAGV-SGGLSPISTPLSDVFMFTIEGEGLTLEqKRTLLDWT---VRPALRGLPGVADVNVLGGR 180
Cdd:PRK10555 103 AVQQVQNQLQSAMRKLPQAVqNQGVTVRKTGDTNILTIAFVSTDGSMD-KQDIADYVasnIQDPLSRVNGVGDIDAYGSQ 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 181 AkTFEVSPDPAALAASGLTAQAIIDAIPASNRNDGSGRL----SEGEEAL--VVRVAGAITSLDDLRDTAIAL-PSGGAA 253
Cdd:PRK10555 182 Y-SMRIWLDPAKLNSFQMTTKDVTDAIESQNAQIAVGQLggtpSVDKQALnaTINAQSLLQTPEQFRDITLRVnQDGSEV 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 254 RLGDLAEVSEGA-----LTRYgavteNGREEAVQAIVIAlRGADAKAVVRSVEARLKELQPSLPKGVTVSPFYNRSDLIQ 328
Cdd:PRK10555 261 TLGDVATVELGAekydyLSRF-----NGKPASGLGVKLA-SGANEMATAKLVLNRLDELAQYFPHGLEYKVAYETTSFVK 334
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 329 RATGTVNKALVEATVLVVILLLLFLGDLRAATVVAVTLPLAALTTFLLMRTFGLSANLMSLGGLAIAIGMLVDAAVVVVE 408
Cdd:PRK10555 335 ASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSINTLTMFAMVLAIGLLVDDAIVVVE 414
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 409 NtVERLD-----NPNIAGSRRLHAIYEAVAEVAapvtsgvLIICLVFLPLLSLQGLEGKLFAPVALTIVFALGSSLLLSF 483
Cdd:PRK10555 415 N-VERIMseeglTPREATRKSMGQIQGALVGIA-------MVLSAVFVPMAFFGGTTGAIYRQFSITIVSAMVLSVLVAM 486
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 484 TVIPVLASLLLK----AHPHRE----SWIMR---RIGPFYERQLARSLSRPKP---VFAAAGGGMVLaaiAYVLIGKSFM 549
Cdd:PRK10555 487 ILTPALCATLLKplkkGEHHGQkgffGWFNRmfnRNAERYEKGVAKILHRSLRwilIYVLLLGGMVF---LFLRLPTSFL 563
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 550 PTMDEGAILMQLaKLPSinlDASAKQDMAV-----QRAILAQVPEVKRIVARVGSDELGldpMGLNETDSFLVLadrKDW 624
Cdd:PRK10555 564 PLEDRGMFTTSV-QLPS---GSTQQQTLKVvekveKYYFTHEKDNVMSVFATVGSGPGG---NGQNVARMFIRL---KDW 633
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 625 RRKDKAwlteeIRKVAAQFPGVEATFTQPIEMRVSEMLTGSRGDLAVKVfGPDLQtLGDLAG-----------RIEETLK 693
Cdd:PRK10555 634 DERDSK-----TGTSFAIIERATKAFNKIKEARVIASSPPAISGLGSSA-GFDME-LQDHAGaghdalmaarnQLLALAA 706
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 694 KTRGASDVYTVAGDSVTYLQLDVDRGAAVRAGLSAQALQQELRAQLEGAPAGVVFEQGKRTPILVRGPQDLREDPVLFEQ 773
Cdd:PRK10555 707 KNPELTRVRHNGLDDSPQLQIDIDQRKAQALGVSIDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAPYRMLPDDINL 786
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 774 AQIATPDGGVVRAGDVARIQRREGPVKIDRENasrfaviqayvqGRDLVGFVKEAQANV----ARDV------PLPPGYR 843
Cdd:PRK10555 787 WYVRNKDGGMVPFSAFATSRWETGSPRLERYN------------GYSAVEIVGEAAPGVstgtAMDImeslvkQLPNGFG 854
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 844 IAWGGQFENQKRAAARLGVVVPMALCLIFLVLFISLKSTRQSLLILANIPFAMIGGLVALWISGEYLSVPASVGLIALLG 923
Cdd:PRK10555 855 LEWTAMSYQERLSGAQAPALYAISLLVVFLCLAALYESWSVPFSVMLVVPLGVIGALLATWMRGLENDVYFQVGLLTVIG 934
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1243374125 924 IAVLNGLVLVSHFNELVQRGCDVATAVTEGARRRLRPVLMTASITALGLVPLLTATGPGSEIQRPLAIVVVGG 996
Cdd:PRK10555 935 LSAKNAILIVEFANEMNQKGHDLFEATLHASRQRLRPILMTSLAFIFGVLPMATSTGAGSGSQHAVGTGVMGG 1007
|
|
| PRK10503 |
PRK10503 |
MdtB/MuxB family multidrug efflux RND transporter permease subunit; |
33-996 |
2.51e-62 |
|
MdtB/MuxB family multidrug efflux RND transporter permease subunit;
Pssm-ID: 182501 [Multi-domain] Cd Length: 1040 Bit Score: 230.39 E-value: 2.51e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 33 LPVDAFPDISPTQVKIILKAPGMTPEEVESQVITPLEMELLGIP--KQAMLRSTAKYAIADLTIDFAPGTDVywARQQTA 110
Cdd:PRK10503 41 LPVSALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSglKQMSSQSSGGASVITLQFQLTLPLDV--AEQEVQ 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 111 ERLSNALGALPAG-----VSGGLSPISTPlsdVFMFTIEGEGLTLEQKRTLLDWTVRPALRGLPGVADVNVLGGRAKTFE 185
Cdd:PRK10503 119 AAINAATNLLPSDlpnppVYSKVNPADPP---IMTLAVTSTAMPMTQVEDMVETRVAQKISQVSGVGLVTLSGGQRPAVR 195
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 186 VSPDPAALAASGLTAQAIIDAIPASNRNDGSGRLSEGEEALVVRVAGAITSLDDLRDTAIALPSGGAARLGDLAEVSEGA 265
Cdd:PRK10503 196 VKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDGPTRAVTLSANDQMQSAEEYRQLIIAYQNGAPIRLGDVATVEQGA 275
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 266 LTRYGAVTENGReeavQAIVIALR---GADAKAVVRSVEARLKELQPSLPKGVTVSPFYNRSDLIQRATGTVNKALVEAT 342
Cdd:PRK10503 276 ENSWLGAWANKQ----QAIVMNVQrqpGANIIATADSIRQMLPQLTESLPKSVKVTVLSDRTTNIRASVDDTQFELMLAI 351
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 343 VLVVILLLLFLGDLRAATVVAVTLPLAALTTFLLMRTFGLSANLMSLGGLAIAIGMLVDAAVVVVENTVERLDNpniaGS 422
Cdd:PRK10503 352 ALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALTIATGFVVDDAIVVIENISRYIEK----GE 427
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 423 RRLHAIYEAVAEVAAPVTSGVLIICLVFLPLLSLQGLEGKLFAPVALTIVFALGSSLLLSFTVIPVLASLLLKAHPHRE- 501
Cdd:PRK10503 428 KPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAVTLAVAILISAVVSLTLTPMMCARMLSQESLRKq 507
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 502 -------SWIMRRIGPFYERQLARSLSRPKPVFAAAGGGMVLAAIAYVLIGKSFMPTMDEGAILMQLAKLPSINLDASAK 574
Cdd:PRK10503 508 nrfsrasERMFDRVIAAYGRGLAKVLNHPWLTLSVALSTLLLTVLLWIFIPKGFFPVQDNGIIQGTLQAPQSSSFANMAQ 587
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 575 QDMAVQRAILaQVPEVKRIVARVGSDelGLDPmGLNETDSFLVL---ADRKDwrRKDKawLTEEIRKVAAQFPGVEaTFT 651
Cdd:PRK10503 588 RQRQVADVIL-QDPAVQSLTSFVGVD--GTNP-SLNSARLQINLkplDERDD--RVQK--VIARLQTAVAKVPGVD-LYL 658
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 652 QPIEMRVSEMlTGSRGDLAVKVFGPDLQTLGDLAGRIEETLKKTRGASDVYTVAGDSVTYLQLDVDRGAAVRAGLSAQAL 731
Cdd:PRK10503 659 QPTQDLTIDT-QVSRTQYQFTLQATSLDALSTWVPKLMEKLQQLPQLSDVSSDWQDKGLVAYVNVDRDSASRLGISMADV 737
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 732 QQELRAQLEGAPAGVVFEQGKRTPILVRgpQDLREDPVL--FEQAQIATPDGGVVRAGDVARIQRREGPVKIDRENASRF 809
Cdd:PRK10503 738 DNALYNAFGQRLISTIYTQANQYRVVLE--HNTENTPGLaaLDTIRLTSSDGGVVPLSSIATIEQRFGPLSINHLDQFPS 815
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 810 AVIQAYVQGRDLVGFVKEAQANVARDVPLPPGYRIAWGGQFENQKRAAARLGVVVPMALCLIFLVLFISLKSTRQSLLIL 889
Cdd:PRK10503 816 TTISFNVPDGYSLGDAVQAIMDTEKTLNLPADITTQFQGSTLAFQSALGSTVWLIVAAVVAMYIVLGVLYESFIHPITIL 895
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 890 ANIPFAMIGGLVALWISGEYLSVPASVGLIALLGIAVLNGLVLVShFNELVQR--GCDVATAVTEGARRRLRPVLMTASI 967
Cdd:PRK10503 896 STLPTAGVGALLALMIAGSELDVIAIIGIILLIGIVKKNAIMMID-FALAAEReqGMSPRDAIYQACLLRFRPILMTTLA 974
|
970 980
....*....|....*....|....*....
gi 1243374125 968 TALGLVPLLTATGPGSEIQRPLAIVVVGG 996
Cdd:PRK10503 975 ALLGALPLMLSTGVGAELRRPLGICMVGG 1003
|
|
| PRK09579 |
PRK09579 |
multidrug efflux RND transporter permease subunit; |
25-996 |
1.19e-60 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169983 [Multi-domain] Cd Length: 1017 Bit Score: 225.10 E-value: 1.19e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 25 LGANAFLKLPVDAFPDISPTQVKIILKAPGMTPEEVESQVITPLEMELLGIPKQAMLRSTAKYAIADLTIDFAPGTDVYW 104
Cdd:PRK09579 24 LGFQAWSKLQIRQYPQMENALITVTTAYPGANAETIQGYITQPLQQSLASAEGIDYMTSVSRQNFSIISIYARIGADSDR 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 105 ARQQTAERLSNALGALPAGVSGG-LSPISTPLSDVFMFTIEGEGLTLEQKRTLLDWTVRPALRGLPGVADVNVLGGRAKT 183
Cdd:PRK09579 104 LFTELLAKANEVKNQLPQDAEDPvLSKEAADASALMYISFYSEEMSNPQITDYLSRVIQPKLATLPGMAEAEILGNQVFA 183
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 184 FEVSPDPAALAASGLTAQAIIDAIPASNRNDGSGRLsEGEeaLVVRVAGAITSLDDLRD-TAIALPSGGAAR--LGDLAE 260
Cdd:PRK09579 184 MRLWLDPVKLAGFGLSAGDVTQAVRRYNFLSAAGEV-KGE--YVVTSINASTELKSAEAfAAIPVKTSGDSRvlLGDVAR 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 261 VSEGAlTRYGAVTENGREEAVQAIVIALRGADAKAVVRSVEARLKELQPSLPKGVTVSPFYNRSDLIQRATGTVNKALVE 340
Cdd:PRK09579 261 VEMGA-ENYDSISSFDGIPSVYIGIKATPSANPLDVIKEVRAIMPELESQLPPNLKVSIAYDATLFIQASIDEVVKTLGE 339
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 341 ATVLVVILLLLFLGDLRAATVVAVTLPLAALTTFLLMRTFGLSANLMSLGGLAIAIGMLVDAAVVVVENTVERLDNpnia 420
Cdd:PRK09579 340 AVLIVIVVVFLFLGALRSVLIPVVTIPLSMIGVLFFMQMMGYSINLLTLLAMVLAIGLVVDDAIVVVENIHRHIEE---- 415
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 421 GSRRLHAIYEAVAEVAAPVTSGVLIICLVFLPLLSLQGLEGKLFAPVALTIVFALGSSLLLSFTVIPVLASLLLKAH--- 497
Cdd:PRK09579 416 GKSPFDAALEGAREIAMPVVSMTITLAAVYAPIGFLTGLTGALFKEFALTLAGAVIISGIVALTLSPMMCALLLRHEenp 495
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 498 ---PHRESWIMRRIGPFYERQLARSL-SRPKP-VFAAagggMVLAAIAYVLI--GKSFMPTMDEGAILMQLAKLPSINLD 570
Cdd:PRK09579 496 sglAHRLDRLFERLKQRYQRALHGTLnTRPVVlVFAV----IVLALIPVLLKftQSELAPEEDQGIIFMMSSSPQPANLD 571
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 571 -ASAKQDMAVQraILAQVPEVKRIVARVGSDELGLDPMGlnetdsFLVladrKDWRRKDKAW--LTEEIRKVAAQFPGVE 647
Cdd:PRK09579 572 yLNAYTDEFTP--IFKSFPEYYSSFQINGFNGVQSGIGG------FLL----KPWNERERTQmeLLPLVQAKLEEIPGLQ 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 648 A-TFTQPiemrvseMLTGSRGDLAvkvFGPDLQTLGDLAGRIE--ETLKKTRGASDVYTVAGDSVTY----LQLDVDRGA 720
Cdd:PRK09579 640 IfGFNLP-------SLPGTGEGLP---FQFVINTANDYESLLQvaQRVKQRAQESGKFAFLDIDLAFdkpeVVVDIDRAK 709
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 721 AVRAGLSAQALQQELRAQLEGAPAGVVFEQGKRTPILVRGPQDLREDPVLFEQAQIATPDGGVVRAGDVARIQRREGPVK 800
Cdd:PRK09579 710 AAQMGVSMQDLGGTLATLLGEGEINRFTIDGRSYKVIAQVERPYRDNPGWLNNYYVKNEQGQLLPLSTLITLSDRARPRQ 789
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 801 IDRENASRFAVIqayvQGRDLV--GFVKEAQANVARDvPLPPGYRIAWGGQFENQKRAAARLGVVVPMALCLIFLVLFIS 878
Cdd:PRK09579 790 LNQFQQLNSAII----SGFPIVsmGEAIETVQQIARE-EAPEGFAFDYAGASRQYVQEGSALWVTFGLALAIIFLVLAAQ 864
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 879 LKSTRQSLLILANIPFAMIGGLVALWISGEYLSVPASVGLIALLGIAVLNGLVLVSHFNEL-VQRGCDVATAVTEGARRR 957
Cdd:PRK09579 865 FESFRDPLVILVTVPLSICGALIPLFLGVSSMNIYTQVGLVTLIGLISKHGILIVEFANQLrHEQGLSRREAIEEAAAIR 944
|
970 980 990
....*....|....*....|....*....|....*....
gi 1243374125 958 LRPVLMTASITALGLVPLLTATGPGSEIQRPLAIVVVGG 996
Cdd:PRK09579 945 LRPVLMTTAAMVFGMVPLILATGAGAVSRFDIGLVIATG 983
|
|
| PRK09577 |
PRK09577 |
multidrug efflux RND transporter permease subunit; |
26-996 |
1.75e-58 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169981 [Multi-domain] Cd Length: 1032 Bit Score: 218.95 E-value: 1.75e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 26 GANAFLKLPVDAFPDISPTQVKIILKAPGMTPEEVESQVITPLEMELLGIPKQAMLRSTAKYAIADLTIDFAPGTDVYWA 105
Cdd:PRK09577 23 GIFAIRALPVAQYPDIAPPVVSIYATYPGASAQVVEESVTALIEREMNGAPGLLYTSATSSAGQASLSLTFKQGVNADLA 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 106 RQQTAERLSNALGALP-----AGVSGGLSPISTPLsdVFMFTIEGEGLTLEQKRTLLDWTVRPALRGLPGVADVNVLGGR 180
Cdd:PRK09577 103 AVEVQNRLKTVEARLPepvrrDGIQVEKAADNIQL--IVSLTSDDGRLTGVELGEYASANVLQALRRVEGVGKVQFWGAE 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 181 AkTFEVSPDPAALAASGLTAQAIIDAIPASNRN---DGSGRLSEGEEALV---VRVAGAITSLDDLRdtAIAL---PSGG 251
Cdd:PRK09577 181 Y-AMRIWPDPVKLAALGLTASDIASAVRAHNARvtiGDIGRSAVPDSAPIaatVFADAPLKTPEDFG--AIALrarADGS 257
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 252 AARLGDLAEVSEGAlTRYGAVTE-NGREEAVQAIVIAlRGADAKAVVRSVEARLKELQPSLPKGVTVSPFYNRSDLIQRA 330
Cdd:PRK09577 258 ALYLRDVARIEFGG-NDYNYPSYvNGKTATGMGIKLA-PGSNAVATEKRVRATMDELSRYFPPGVKYQIPYETSSFVRVS 335
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 331 TGTVNKALVEATVLVVILLLLFLGDLRAATVVAVTLPLAALTTFLLMRTFGLSANLMSLGGLAIAIGMLVDAAVVVVENt 410
Cdd:PRK09577 336 MNKVVTTLIEAGVLVFLVMFLFMQNFRATLIPTLVVPVALLGTFGVMLAAGFSINVLTMFGMVLAIGILVDDAIVVVEN- 414
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 411 VERLDNPNiaGSRRLHAIYEAVAEVAAPVTSGVLIICLVFLPLLSLQGLEGKLFAPVALTIVFALGSSLLLSFTVIPVLA 490
Cdd:PRK09577 415 VERLMVEE--GLSPYDATVKAMKQISGAIVGITVVLTSVFVPMAFFGGAVGNIYRQFALSLAVSIGFSAFLALSLTPALC 492
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 491 SLLLK--AHPHRES-----WIMRRIGPF---YERQLARSLSRPKPVFAAAGGGMVLAAIAYVLIGKSFMPTMDEGAiLMQ 560
Cdd:PRK09577 493 ATLLKpvDGDHHEKrgffgWFNRFVARStqrYATRVGAILKRPLRWLVVYGALTAAAALLFTRLPTAFLPDEDQGN-FMV 571
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 561 LAKLPSINLDASAKQDMAVQRAILAQVPEVKRIVARVGSDELGLDPmglnetDSFLVLADRKDW--RRKDKAWLTEEIRK 638
Cdd:PRK09577 572 MVIRPQGTPLAETMQSVREVESYLRRHEPVAYTFALGGFNLYGEGP------NGGMIFVTLKDWkeRKAARDHVQAIVAR 645
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 639 VAAQFPGVEATFTQPIEMRVSEMLTGSRG-DLAVKVFGP-DLQTLGDLAGRIEETLKKTRGASDVYTVAGDSVTYLQLDV 716
Cdd:PRK09577 646 INERFAGTPNTTVFAMNSPALPDLGSTSGfDFRLQDRGGlGYAAFVAAREQLLAEGAKDPALTDLMFAGTQDAPQLKLDI 725
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 717 DRGAAVRAGLSAQALQQELRAQLEGAPAGVVFEQGKRTPILVRGPQDLREDPVLFEQAQIATPDGGVVRAGDVARIQRRE 796
Cdd:PRK09577 726 DRAKASALGVSMDEINTTLAVMFGSDYIGDFMHGSQVRRVIVQADGRHRLDPDDVKKLRVRNAQGEMVPLAAFATLHWTL 805
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 797 GPVKIDRENA-SRFAVIQAYVQGRDlvgfVKEAQANVARDV-PLPPGYRIAWGGQFENQKRAAARlgvvVPMALCLIFLV 874
Cdd:PRK09577 806 GPPQLTRYNGyPSFTINGSAAPGHS----SGEAMAAIERIAaTLPAGIGYAWSGQSFEERLSGAQ----APMLFALSVLV 877
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 875 LFISLKSTRQSLLI----LANIPFAMIGGLVALWISGEYLSVPASVGLIALLGIAVLNGLVLVSHFNELVQRGCDVATAV 950
Cdd:PRK09577 878 VFLALAALYESWSIpfavMLVVPLGVIGAVLGVTLRGMPNDIYFKVGLIATIGLSAKNAILIVEVAKDLVAQRMSLADAA 957
|
970 980 990 1000
....*....|....*....|....*....|....*....|....*.
gi 1243374125 951 TEGARRRLRPVLMTASITALGLVPLLTATGPGSEIQRPLAIVVVGG 996
Cdd:PRK09577 958 LEAARLRLRPIVMTSLAFGVGVLPLAFASGAASGAQIAIGTGVLGG 1003
|
|
| PRK10614 |
PRK10614 |
multidrug efflux system subunit MdtC; Provisional |
26-996 |
5.30e-54 |
|
multidrug efflux system subunit MdtC; Provisional
Pssm-ID: 182589 [Multi-domain] Cd Length: 1025 Bit Score: 204.96 E-value: 5.30e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 26 GANAFLKLPVDAFPDISPTQVKIILKAPGMTPEEVESQVITPLEMELLGIPKQAMLRSTAKYAIADLTIDFAPGTDVYWA 105
Cdd:PRK10614 25 GILGFRLLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVNEMTSSSSLGSTRIILQFDFDRDINGA 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 106 RQQTAERLSNALGALPAGVSGGLSPISTPLSD--VFMFTIEGEGLTLEQKRTLLDWTVRPALRGLPGVADVNVLGGRAKT 183
Cdd:PRK10614 105 ARDVQAAINAAQSLLPSGMPSRPTYRKANPSDapIMILTLTSDTYSQGQLYDFASTQLAQTISQIDGVGDVDVGGSSLPA 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 184 FEVSPDPAALAASGLTAQAIIDAIPASNRNDGSGRLSEGEEALVVRVAGAITSLDDLRDTAIALPSGGAARLGDLAEVSE 263
Cdd:PRK10614 185 VRVGLNPQALFNQGVSLDDVRQAISNANVRRPQGAVEDGTHRWQIQTNDELKTAAEYQPLIIHYNNGAAVRLGDVATVTD 264
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 264 GALTRYGAVTENGREeavqAIVIALR---GADAKAVVRSVEARLKELQPSLPKGVTVSPFYNRSDLIQRATGTVNKALVE 340
Cdd:PRK10614 265 SVQDVRNAGMTNAKP----AILLMIRklpEANIIQTVDRIRAKLPELRETIPAAIDLQIAQDRSPTIRASLEEVEQTLAI 340
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 341 ATVLVVILLLLFLGDLRAATVVAVTLPLAALTTFLLMRTFGLSANLMSLGGLAIAIGMLVDAAVVVVENTVERLDnpniA 420
Cdd:PRK10614 341 SVALVILVVFLFLRSGRATLIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDDAIVVLENISRHLE----A 416
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 421 GSRRLHAIYEAVAEVAAPVTSGVLIICLVFLPLLSLQGLEGKLFAPVALTIVFALGSSLLLSFTVIPVLASLLLKAHPHR 500
Cdd:PRK10614 417 GMKPLQAALQGVREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLFREFAVTLSVAIGISLLVSLTLTPMMCAWLLKSSKPR 496
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 501 ESWIMRRIGPF-------YERQLARSLSRPKPVFAAAGGGMVLAAIAYVLIGKSFMPTMDEGAILMQLAKLPSINLDAsA 573
Cdd:PRK10614 497 EQKRLRGFGRMlvalqqgYGRSLKWVLNHTRWVGVVLLGTIALNVWLYISIPKTFFPEQDTGRLMGFIQADQSISFQA-M 575
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 574 KQDMAVQRAILAQVPEVKRIVARVGSDELGLDPMglnetdsFLVLADRKDwRRKDKAWLTEEIRKVAAQFPGVEATFtqp 653
Cdd:PRK10614 576 RGKLQDFMKIIRDDPAVDNVTGFTGGSRVNSGMM-------FITLKPLSE-RSETAQQVIDRLRVKLAKEPGANLFL--- 644
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 654 ieMRVSEMLTGSRGDLAVKVF---GPDLQTLGDLAGRIEETLKKTRGASDVYTVAGDSVTYLQLDVDRGAAVRAGLSAQA 730
Cdd:PRK10614 645 --MAVQDIRVGGRQSNASYQYtllSDDLAALREWEPKIRKALAALPELADVNSDQQDKGAEMALTYDRDTMARLGIDVQA 722
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 731 LQQELRAQLEGAPAGVVFEQGKRTPILVRGPQDLREDPVLFEQAQIATPDGGVVRAGDVARIQRREGPVKIDRENASRFA 810
Cdd:PRK10614 723 ANSLLNNAFGQRQISTIYQPLNQYKVVMEVDPRYTQDISALEKMFVINNEGKAIPLSYFAKWQPANAPLSVNHQGLSAAS 802
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 811 VIQAYV-QGRDLvgfvKEAQANVARDVP---LPPGYRIAWGGQFENQKRAAARLGVVVPMALCLIFLVLFISLKSTRQSL 886
Cdd:PRK10614 803 TISFNLpTGKSL----SDASAAIERAMTqlgVPSTVRGSFAGTAQVFQETMNSQLILILAAIATVYIVLGILYESYVHPL 878
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 887 LILANIPFAMIGGLVALWISGEYLSVPASVGLIALLGIAVLNGLVLVShFNELVQR--GCDVATAVTEGARRRLRPVLMT 964
Cdd:PRK10614 879 TILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMMVD-FALEAQRngNLTAQEAIFQACLLRFRPIMMT 957
|
970 980 990
....*....|....*....|....*....|..
gi 1243374125 965 ASITALGLVPLLTATGPGSEIQRPLAIVVVGG 996
Cdd:PRK10614 958 TLAALFGALPLVLSGGDGAELRQPLGITIVGG 989
|
|
| PRK15127 |
PRK15127 |
multidrug efflux RND transporter permease subunit AcrB; |
26-996 |
5.08e-52 |
|
multidrug efflux RND transporter permease subunit AcrB;
Pssm-ID: 185081 [Multi-domain] Cd Length: 1049 Bit Score: 198.97 E-value: 5.08e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 26 GANAFLKLPVDAFPDISPTQVKIILKAPGMTPEEVESQVITPLEMELLGIPKQAMLRSTAKYA-IADLTIDFAPGTDVYW 104
Cdd:PRK15127 23 GGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSSNSDSTgTVQITLTFESGTDADI 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 105 ARQQTAERLSNALGALPAGVSGGLSPISTPLSDVFM---FTIEGEGLTLEQKRTLLDWTVRPALRGLPGVADVNVLGGRA 181
Cdd:PRK15127 103 AQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMvvgVINTDGTMTQEDISDYVAANMKDPISRTSGVGDVQLFGSQY 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 182 kTFEVSPDPAALAASGLTAQAIIDAIPASNRNDGSGRLS-----EGEEALVVRVAGA-ITSLDDLRDTAIALPSGGA-AR 254
Cdd:PRK15127 183 -AMRIWMNPNELNKFQLTPVDVINAIKAQNAQVAAGQLGgtppvKGQQLNASIIAQTrLTSTEEFGKILLKVNQDGSrVR 261
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 255 LGDLAEVSEGAlTRYGAVTE-NGREEAVQAIVIAlRGADAKAVVRSVEARLKELQPSLPKGVTVSPFYNRSDLIQRATGT 333
Cdd:PRK15127 262 LRDVAKIELGG-ENYDIIAEfNGQPASGLGIKLA-TGANALDTAAAIRAELAKMEPFFPSGLKIVYPYDTTPFVKISIHE 339
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 334 VNKALVEATVLVVILLLLFLGDLRAATVVAVTLPLAALTTFLLMRTFGLSANLMSLGGLAIAIGMLVDAAVVVVENtVER 413
Cdd:PRK15127 340 VVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIGLLVDDAIVVVEN-VER 418
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 414 LDN-----PNIAGSRRLHAIYEAVAEVAapvtsgvLIICLVFLPLLSLQGLEGKLFAPVALTIVFALGSSLLLSFTVIPV 488
Cdd:PRK15127 419 VMAeeglpPKEATRKSMGQIQGALVGIA-------MVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPA 491
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 489 LASLLLKA-----HPHRESWIMRRIGPFYERQ----------LARSLSRPKPVFAAAGGGMvlaAIAYVLIGKSFMPTMD 553
Cdd:PRK15127 492 LCATMLKPiakgdHGEGKKGFFGWFNRMFEKSthhytdsvgnILRSTGRYLVLYLIIVVGM---AYLFVRLPSSFLPDED 568
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 554 EGaILMQLAKLPsinldASAKQDMAvqRAILAQVP------EVKRIVARVGSDELGLDPMGLNETDSFLVLadrKDWRRK 627
Cdd:PRK15127 569 QG-VFLTMVQLP-----AGATQERT--QKVLNEVTdyyltkEKNNVESVFAVNGFGFAGRGQNTGIAFVSL---KDWADR 637
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 628 dkawlTEEIRKVAAQFPGVEATFTQPIEMRVSEMLTGSRGDLAVKVfGPDLQtLGDLAGRIEETLKKTRG------ASDV 701
Cdd:PRK15127 638 -----PGEENKVEAITMRATRAFSQIKDAMVFAFNLPAIVELGTAT-GFDFE-LIDQAGLGHEKLTQARNqllgeaAKHP 710
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 702 YTVAG------DSVTYLQLDVDRGAAVRAGLSAQALQQELRAQLEGAPAGVVFEQGKRTPILVRGPQDLREDPVLFEQAQ 775
Cdd:PRK15127 711 DMLVGvrpnglEDTPQFKIDIDQEKAQALGVSISDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGDWY 790
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 776 IATPDGGVVRAGDVARIQRREGPVKIDRENASRFAVIQAYVQGRDLVGFVKEAQANVARDVPLPPGYRiaWGGQFENQKR 855
Cdd:PRK15127 791 VRAADGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEELASKLPTGVGYD--WTGMSYQERL 868
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 856 AAARLGVVVPMALCLIFLVLFISLKSTRQSLLILANIPFAMIGGLVALWISGEYLSVPASVGLIALLGIAVLNGLVLVSH 935
Cdd:PRK15127 869 SGNQAPALYAISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEF 948
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1243374125 936 FNELVQR-GCDVATAVTEGARRRLRPVLMTASITALGLVPLLTATGPGSEIQRPLAIVVVGG 996
Cdd:PRK15127 949 AKDLMDKeGKGLIEATLEAVRMRLRPILMTSLAFILGVMPLVISSGAGSGAQNAVGTGVMGG 1010
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
2-500 |
1.11e-18 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 92.09 E-value: 1.11e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 2 RKLIAFALSQRLLAAVLAIALVGLGANAFLKLPVDAFPDISPTQVKIILKAP-GMTPEEVEsQVITPLEMELLGIPKQAM 80
Cdd:COG0841 516 GRLLRWALRHRKLTLLVALALLALSVLLFGRLPTEFFPEEDQGQIIVSVQLPpGTSLERTE-AVVRQVEEILLEVPEVES 594
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 81 LRSTAKYAI-------ADLTIDFAPGTDVYWARQQTAERLSNALGALPAG------VSGGLSPISTPLSdvfmFTIEGEG 147
Cdd:COG0841 595 VFSVVGFSGggsgsnsGTIFVTLKPWDERDRSADEIIARLREKLAKIPGArvfvfqPPAGGLGSGAPIE----VQLQGDD 670
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 148 LtleqkRTLLDWT--VRPALRGLPGVADVNV-LGGRAKTFEVSPDPAALAASGLTAQAIIDAIPASNRNDGSGRLSEGEE 224
Cdd:COG0841 671 L-----EELAAAAekLLAALRQIPGLVDVRSdLQLGKPELQLDIDREKAAALGVTVADVASTLRAALGGRYVNDFNRGGR 745
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 225 ALVVRV---AGAITSLDDLRDTAIALPSGGAARLGDLAEVSEGA----LTRYgavteNGREEA-VQAIViaLRGADAKAV 296
Cdd:COG0841 746 EYDVRVqapEEDRNSPEDLENLYVRTPDGEMVPLSSVATIEEGTgpssINRY-----NGQRSVtVSANL--APGVSLGEA 818
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 297 VRSVEARLKELQpsLPKGVTVSpFYNRSDLIQRATGTVNKALveatvlvvillllflgdlrAATVVAV------------ 364
Cdd:COG0841 819 LAAIEELAAELK--LPPGVSIE-FTGQAEEEQESFSSLGLAF-------------------LLALLLVylvlaaqfesfi 876
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 365 -------TLPLAALTTFLLMRTFGLSANLMSLGGLAIAIGMLVDAAVVVVENTVERLDnpniAGSRRLHAIYEAVAEVAA 437
Cdd:COG0841 877 qpliillTVPLALIGALLGLLLTGTPLNIYSQIGLIMLIGIVVKNAILLVDFANQLRE----EGMSLREAILEAARLRLR 952
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1243374125 438 PV--TSGVLIICLvfLPLLSLQGLEGKLFAPVALTIVFALGSSLLLSFTVIPVLASLLLKAHPHR 500
Cdd:COG0841 953 PIlmTSLATILGL--LPLALGTGAGAEFRQPLGIAVIGGLLFSTLLTLFVVPVLYVLLDRLRRRL 1015
|
|
| CusA |
COG3696 |
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism]; |
161-502 |
1.53e-12 |
|
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
Pssm-ID: 442911 [Multi-domain] Cd Length: 1031 Bit Score: 71.98 E-value: 1.53e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 161 VRPALRGLPGVADVNV---LGGRakTFEVSPDPAALAASGLTAQAIIDAIPASNRNDGSGRLSEGEE--ALVVRVAGAI- 234
Cdd:COG3696 694 IEAVLKTVPGAADVQVervTGLP--QLDIRIDRDAAARYGLNVADVQDVVETAIGGKAVGQVYEGERrfDIVVRLPEELr 771
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 235 TSLDDLRDTAIALPSGGAARLGDLAEVSEGAltryGAVT---ENGREeaVQAIVIALRGADAKAVVRSVEARLKElQPSL 311
Cdd:COG3696 772 DDPEAIRNLPIPTPSGAQVPLSQVADIEVVE----GPNQisrENGRR--RIVVQANVRGRDLGSFVAEAQAKVAE-QVKL 844
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 312 PKGVTVS---PFYNRsdliQRATgtvnkalveatvlvvillllflgdLRAATVVAVTLplaALTTFLLMRTFG-LSANLM 387
Cdd:COG3696 845 PPGYYIEwggQFENL----QRAT------------------------ARLAIVVPLAL---LLIFLLLYLAFGsVRDALL 893
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 388 SLGGLAIAI--GML----------VDAAV-------VVVENTV---ERLDNPNIAGSRRLHAIYEAVAEVAAPVTSGVLI 445
Cdd:COG3696 894 ILLNVPFALigGVLalwlrgmplsVSAGVgfialfgVAVLNGVvlvSYINQLRAEGLDLREAIIEGALERLRPVLMTALV 973
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1243374125 446 ICLVFLPLLslqglegklFA---------PVALTIVFALGSSLLLSFTVIPVLASLLLKAHPHRES 502
Cdd:COG3696 974 AALGLLPMA---------LStgpgsevqrPLATVVIGGLITSTLLTLLVLPALYLLFGRRRLRRAA 1030
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
2-489 |
4.24e-10 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 63.85 E-value: 4.24e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 2 RKLIAFALSQRLLAAVLAIALVGLGANAFLKLPVDAFPDISPTQVKIILKAPGMTPEEVESQVITPLEMELLGIPKQAML 81
Cdd:pfam00873 517 AKLLAKVLRHTAVVLLVALLLVVGSVWLFVRIPTEFLPEEDEGVFVTSAQLPPGVSLDQTQRVMKQVEKILKEKPEVESV 596
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 82 RSTAKYAI---------ADLTIDFAPGTDVYWA---RQQTAERLSNALGALPAGVSGGLSPIS------TPLSDV-FMFT 142
Cdd:pfam00873 597 FAVTGFAFsgdnngpnsGDAFISLKPWKERPGPeksVQALIERLRKALKQIPGANVFLFQPIQlrglgtISGFRSdLQVK 676
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 143 IEGEGLtleqkRTLLDWT--VRPALRGLPGVADVNVLG-GRAKTFEVSPDPAALAASGLTAQAIIDAIpaSNRNDGS--- 216
Cdd:pfam00873 677 IFGDDL-----DALDEARnqILAALAQLPGLSDVRSDGqEDQPQLQVNIDREKAARLGVSIQDINDTL--STALGGSyvn 749
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 217 -----GRLSEgeeaLVVRVAGAIT-SLDDLRDTAIALPSGGAARLGDLAEVSEGaltrYGAVTENgREEAVQAIVIA--L 288
Cdd:pfam00873 750 dfpegGRVYD----VVVQLPEDFRsSPEDIGQLYVRNPYGKMIPLSAFAKIEWG----YGPPSIN-RYNGFRSIVISgnV 820
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 289 RGADAKAVVRSVEARLKElQPSLPKGVTVSP---FYNRsdliQRATGTVNKALVEATVLVVILLLLFLGDLRAATVVAVT 365
Cdd:pfam00873 821 AAGDSLGDAMEAMAQIAK-QVKLPPGYGYTWtgqFEQE----QLAGNSLPILIALALLVVFLVLAALYESWSDPLSIMLT 895
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 366 LPLAALTTFLLMRTFGLSANLMSLGGLAIAIGMLVDAAVVVVENTVERLDNpniAGSRRLHAIYEAVAEVAAPVTSGVLI 445
Cdd:pfam00873 896 VPLALVGALLALWLRGLPNSVYAQVGLILLIGLAVKNAILMVEFANELREQ---EGKSLEEAILEACRLRLRPILMTALA 972
|
490 500 510 520
....*....|....*....|....*....|....*....|....
gi 1243374125 446 ICLVFLPLLSLQGLEGKLFAPVALTIVFALGSSLLLSFTVIPVL 489
Cdd:pfam00873 973 AILGVLPLALSTGAGSELQQPLGIVVFGGLVTSTVLTLLVVPVF 1016
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
860-978 |
1.87e-08 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 58.33 E-value: 1.87e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 860 LGVVVPMALCLIFLVLFISLKSTRQSLLILANIPFAMIGGLVALWISGEYLSVPASVGLIALLGIAVLNGLVLVSHFNEL 939
Cdd:COG1033 220 LAIFFPLALLLILLLLFLFFRSLRGVLLPLLVVLLAVIWTLGLMGLLGIPLSPLTILVPPLLLAIGIDYGIHLLNRYREE 299
|
90 100 110
....*....|....*....|....*....|....*....
gi 1243374125 940 VQRGCDVATAVTEGARRRLRPVLMTASITALGLVPLLTA 978
Cdd:COG1033 300 RRKGLDKREALREALRKLGPPVLLTSLTTAIGFLSLLFS 338
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
810-982 |
5.38e-07 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 53.71 E-value: 5.38e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 810 AVIQAYVQ---GRDLVGFVKEAQANVARDVPlPPGYRIAWGGQFENQKRAAARLG----VVVPMALCLIFLVLFISLKST 882
Cdd:COG1033 551 ARVTVRLKdldSEEIKALVEEVRAFLAENFP-PDGVEVTLTGSAVLFAAINESVIesqiRSLLLALLLIFLLLLLAFRSL 629
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 883 RQSLLILANIPFAMIGGLVALWISGEYLSvPASVGLIAL-LGIAVLNGLVLVSHFNELVQRGCDVATAVTEGARRRLRPV 961
Cdd:COG1033 630 RLGLISLIPNLLPILLTFGLMGLLGIPLN-IATAVVASIaLGIGVDYTIHFLSRYREERRKGGDLEEAIRRALRTTGKAI 708
|
170 180
....*....|....*....|.
gi 1243374125 962 LMTASITALGLVPLLTATGPG 982
Cdd:COG1033 709 LFTSLTLAAGFGVLLFSSFPP 729
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
357-493 |
6.99e-06 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 50.24 E-value: 6.99e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 357 RAATVVAVTLPLAALTTFLLMRTFGLSANLMSLGGLAIAIGMLVDAAVVVVENTVERLDNpniaGSRRLHAIYEAVAEVA 436
Cdd:COG1033 630 RLGLISLIPNLLPILLTFGLMGLLGIPLNIATAVVASIALGIGVDYTIHFLSRYREERRK----GGDLEEAIRRALRTTG 705
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 1243374125 437 APVTSGVLIICLVFLPL-LSlqglEGKLFAPVALTIVFALGSSLLLSFTVIPVLASLL 493
Cdd:COG1033 706 KAILFTSLTLAAGFGVLlFS----SFPPLADFGLLLALGLLVALLAALLLLPALLLLL 759
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
860-981 |
1.17e-04 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 45.98 E-value: 1.17e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 860 LGVVVPMALCLIFLVLFISLKSTRQSLLILANIPFAMIGGLVALWISGEYLSVPASVGLIALLGIAVLNGLVLVSHFNEL 939
Cdd:TIGR00921 195 MGTTMAISGILVVLVLLLDFKRWWRPLLPLVIILFGVAWVLGIMGWLGIPLYATTLLAVPMLIGVGIDYGIQTLNRYEEE 274
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 1243374125 940 VQRGCDVATAVTEGARRRLRPVLMTASITALGLVPLLTATGP 981
Cdd:TIGR00921 275 RDIGRAKGEAIVTAVRRTGRAVLIALLTTSAGFAALALSEFP 316
|
|
| MMPL |
pfam03176 |
MMPL family; Members of this family are putative integral membrane proteins from bacteria. ... |
806-978 |
6.41e-03 |
|
MMPL family; Members of this family are putative integral membrane proteins from bacteria. Several of the members are mycobacterial proteins. Many of the proteins contain two copies of this aligned region. The function of these proteins is not known, although it has been suggested that they may be involved in lipid transport.
Pssm-ID: 308676 [Multi-domain] Cd Length: 332 Bit Score: 39.97 E-value: 6.41e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 806 ASRFAVIQAYVQGRDLVGFVKEAQANVARDVPLPPGYRIAWGG---QFENQKRAAAR-LGVVVPMALCLIFLVLFISLKS 881
Cdd:pfam03176 86 AAYVVVTLEGDPGTTEADESVAAVRDAVEQAPPPEGLKAYLTGpaaTVADLRDAGDRdLGLIEAVTLVVIFIILLIVYRS 165
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1243374125 882 TRQSLLILANIPFAMIG--GLVALWISGEYLSVPASVGLIA---LLGIAVLNGLVLVSHFNELVQRGCDVATAVTEGARR 956
Cdd:pfam03176 166 VVAALLPLLTVGLSLGAaqGLVAILAHILGIGLSTFALNLLvvlLIAVGTDYALFLVSRYREELRAGEDREEAVIRAVRG 245
|
170 180
....*....|....*....|..
gi 1243374125 957 RLRPVLMTASITALGLVPLLTA 978
Cdd:pfam03176 246 TGKVVTAAGLTVAIAMLALSFA 267
|
|
| |
